A novel AMPA receptor antagonist, YM872, reduces infarct size after middle cerebral artery occlusion in rats

Brain Research

Volumn 793, Issue 1-2, 1998, Pages 39-46

  Kawasaki Yatsugi, Sachiko ^a   Yatsugi, Shin Ichi ^a   Takahashi, Masayasu ^a   Toya, Takashi ^a   Ichiki, Chikako ^a   Shimizu Sasamata, Masao ^a   Yamaguchi, Tokio ^a   Minematsu, Kazuo ^b  

^a Inst for Drug Discovery Research   (Japan)

^b NATIONAL CEREBRAL AND CARDIOVASCULAR CENTER   (Japan)

Author keywords

AMPA antagonist; Focal cerebral ischemia; Rat

Indexed keywords

[2,3 DIOXO 7 (1H IMIDAZOL 1 YL) 6 NITRO 1,2,3,4 TETRAHYDRO 1 QUINOXALINYL] ACETIC ACID; AMPA RECEPTOR ANTAGONIST; UNCLASSIFIED DRUG;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN INFARCTION; BRAIN ISCHEMIA; BRAIN PROTECTION; CONTROLLED STUDY; DRUG EFFECT; INTRAVENOUS DRUG ADMINISTRATION; MALE; NONHUMAN; OCCLUSIVE CEREBROVASCULAR DISEASE; PRIORITY JOURNAL; RAT;

ANIMALS; ARTERIAL OCCLUSIVE DISEASES; BLOOD GAS ANALYSIS; BODY TEMPERATURE; BRAIN; BRAIN ISCHEMIA; CEREBRAL ARTERIES; CEREBRAL INFARCTION; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; IMIDAZOLES; INFUSIONS, INTRAVENOUS; KIDNEY; MALE; NEUROPROTECTIVE AGENTS; QUINOXALINES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, AMPA; TIME FACTORS;

EID: 0032543159     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(98)00108-5     Document Type: Article

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