ZK200775: A phosphonate quinoxalinedione AMPA antagonist for neuroprotection in stroke and trauma

Proceedings of the National Academy of Sciences of the United States of America

Volumn 95, Issue 18, 1998, Pages 10960-10965

  Turski, Lechoslaw ^a,d   Huth, Andreas ^a   Sheardown, Malcolm ^b   Mcdonald, Fiona ^a   Neuhaus, Roland ^a   Schneider, Herbert H ^a   Dirnagl, Ulrich ^c   Wiegand, Frank ^c   Jacobsen, Poul ^b   Ottow, Eckhard ^a  

^a BAYER PHARMA AG   (Germany)

^b NOVO NORDISK A S   (Denmark)

^c HUMBOLDT UNIVERSITY   (Germany)

^d UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

Glutamate antagonists; Ischemic brain damage; Therapeutic time window; Traumatic brain injury

Indexed keywords

[[3,4 DIHYDRO 7 MORPHOLINO 2,3 DIOXO 6 (TRIFLUOROMETHYL) 1(2H) QUINOXALINYL]METHYL]PHOSPHONIC ACID; AMPA RECEPTOR ANTAGONIST; N METHYL DEXTRO ASPARTIC ACID; QUINOXALINE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN ARTERY; BRAIN ISCHEMIA; CAUSE OF DEATH; GERBIL; HEAD INJURY; HIPPOCAMPUS; MOUSE; NEPHROTOXICITY; NEUROPROTECTION; NONHUMAN; PREDICTION; PRIORITY JOURNAL; RAT; REPERFUSION; STROKE;

ALPHA-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID; ANIMALS; CELLS, CULTURED; CEREBROVASCULAR DISORDERS; CRANIOCEREBRAL TRAUMA; EVOKED POTENTIALS; EXCITATORY AMINO ACID ANTAGONISTS; GERBILLINAE; MICE; NEUROPROTECTIVE AGENTS; PHOSPHONIC ACIDS; QUINOXALINES; RADIOLIGAND ASSAY; RATS;

ANIMALIA; GERBILLINAE;

EID: 13144306063     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.95.18.10960     Document Type: Article

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