The Chk1/Cdc25A pathway as activators of the cell cycle in neuronal death induced by camptothecin

Journal of Neuroscience

Volumn 26, Issue 34, 2006, Pages 8819-8828

  Zhang, Yi ^a   Qu, Dianbo ^a   Morris, Erick J ^c   O'Hare, Michael J ^a   Callaghan, Steven M ^a   Slack, Ruth S ^a   Geller, Herbert M ^b   Park, David S ^a  

^a OTTAWA HOSPITAL RESEARCH INSTITUTE   (Canada)

^b NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

^c MASSACHUSETTS GENERAL HOSPITAL CANCER CENTER   (United States)

Author keywords

Apoptosis; Cdc25A; Cell cycle; Chk1; DNA damage; Neurons

Indexed keywords

CAMPTOTHECIN; CHECKPOINT KINASE 1; CYCLIN D1; PROTEIN TYROSINE PHOSPHATASE;

ANIMAL CELL; ARTICLE; BRAIN CELL; CELL CULTURE; CELL CYCLE; CELL CYCLE ARREST; CELL CYCLE REGULATION; CELL DEATH; CELL SURVIVAL; CONTROLLED STUDY; DNA DAMAGE; EMBRYO; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; MOUSE; NERVE CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; WILD TYPE;

ANIMALS; APOPTOSIS; CAMPTOTHECIN; CDC25 PHOSPHATASE; CELL CYCLE; CELLS, CULTURED; CYCLIN-DEPENDENT KINASES; DNA DAMAGE; MICE; MICE, INBRED STRAINS; NEURONS; PROTEIN KINASES; RNA INTERFERENCE;

EID: 33748256674     PISSN: 02706474     EISSN: 02706474     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.2593-06.2006     Document Type: Article

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