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Volumn 14, Issue 7, 2000, Pages 955-967

Oxidative DNA damage precedes DNA fragmentation after experimental stroke in rat brain

Author keywords

Hydroxyl radicals; Neurotoxicity; Oxidative DNA damage; Reactive oxygen species; Stroke

Indexed keywords

DNA FRAGMENT;

EID: 0034014316     PISSN: 08926638     EISSN: None     Source Type: Journal    
DOI: 10.1096/fasebj.14.7.955     Document Type: Article
Times cited : (155)

References (66)
  • 1
    • 0032845121 scopus 로고    scopus 로고
    • Ischemic cell death in brain neurons
    • Lipton, P. (1999) Ischemic cell death in brain neurons. Physiol. Rev. 79, 1431-1568
    • (1999) Physiol. Rev. , vol.79 , pp. 1431-1568
    • Lipton, P.1
  • 3
    • 0031441165 scopus 로고    scopus 로고
    • Differential hydrylation of salicylate in core and penumbra regions during focal reversible cerebral ischemia
    • Solenske, N. J., Kwan, A. L., Yanamoto, H., Benneet, J. P., Kassell, N. F., and Lee, K. S. (1997) Differential hydrylation of salicylate in core and penumbra regions during focal reversible cerebral ischemia. Stroke 28, 2545-2551
    • (1997) Stroke , vol.28 , pp. 2545-2551
    • Solenske, N.J.1    Kwan, A.L.2    Yanamoto, H.3    Benneet, J.P.4    Kassell, N.F.5    Lee, K.S.6
  • 4
    • 0027245908 scopus 로고
    • Nitric oxide measured by a porphyrinic microsensor in rat brain after transient middle cerebral artery occlusion
    • Malinski, T., Bailey, F., Zhang, Z. G., and Chopp, M. (1993) Nitric oxide measured by a porphyrinic microsensor in rat brain after transient middle cerebral artery occlusion. J. Cereb. Blood Flow Metab. 13, 355-358
    • (1993) J. Cereb. Blood Flow Metab. , vol.13 , pp. 355-358
    • Malinski, T.1    Bailey, F.2    Zhang, Z.G.3    Chopp, M.4
  • 5
    • 0028851010 scopus 로고
    • Nitric oxide changes in the rat brain after transient middle cerebral artery occlusion
    • Zhang, Z. G., Chopp, M., Bailey, F., and Malinski, T. (1995) Nitric oxide changes in the rat brain after transient middle cerebral artery occlusion. J. Neurol. Sci. 128, 22-27
    • (1995) J. Neurol. Sci. , vol.128 , pp. 22-27
    • Zhang, Z.G.1    Chopp, M.2    Bailey, F.3    Malinski, T.4
  • 7
    • 0033565586 scopus 로고    scopus 로고
    • Neuronal nitric oxide synthase activation and peroxynitrite formation in ischemic stroke linked to neuronal damage
    • Eliasson, M. L., Huang, Z., Ferrante, R. J., Sasamata, M., Molliver, M. E., Snyder, S. H., and Moskowitz, M. A. (1999) Neuronal nitric oxide synthase activation and peroxynitrite formation in ischemic stroke linked to neuronal damage. J. Neurosci. 19, 5910-5918
    • (1999) J. Neurosci. , vol.19 , pp. 5910-5918
    • Eliasson, M.L.1    Huang, Z.2    Ferrante, R.J.3    Sasamata, M.4    Molliver, M.E.5    Snyder, S.H.6    Moskowitz, M.A.7
  • 8
    • 0029862775 scopus 로고    scopus 로고
    • DNA damage by peroxynitrite characterized with DNA repair enzymes
    • Epe, B., Ballmaier, D., Roussyn, I., Briviba, K., and Sies, H. (1996) DNA damage by peroxynitrite characterized with DNA repair enzymes. Nucleic Acids Res. 24, 4105-4110
    • (1996) Nucleic Acids Res. , vol.24 , pp. 4105-4110
    • Epe, B.1    Ballmaier, D.2    Roussyn, I.3    Briviba, K.4    Sies, H.5
  • 10
    • 0032866416 scopus 로고    scopus 로고
    • Oxidative damage to the c-fos gene and reduction of its transcription after focal cerebral ischemia
    • Cui, J., Holmes, E. H., and Liu, P. K. (1999) Oxidative damage to the c-fos gene and reduction of its transcription after focal cerebral ischemia. J. Neurochem. 73, 1164-1174
    • (1999) J. Neurochem. , vol.73 , pp. 1164-1174
    • Cui, J.1    Holmes, E.H.2    Liu, P.K.3
  • 11
    • 0033973876 scopus 로고    scopus 로고
    • In situ detection of AP sites and DNA strand breaks with 3′-phosphate ends in ischemic mouse brain
    • Huang, D., Shenoy, A., Cui, J. K., Huang, W., and Liu, P. K. (2000) In situ detection of AP sites and DNA strand breaks with 3′-phosphate ends in ischemic mouse brain. FASEB J. 14, 407-417
    • (2000) FASEB J. , vol.14 , pp. 407-417
    • Huang, D.1    Shenoy, A.2    Cui, J.K.3    Huang, W.4    Liu, P.K.5
  • 12
    • 0030916417 scopus 로고    scopus 로고
    • DFF: A heterodimeric protein that functions downstream of caspase-3 to trigger DNA fragmentation during apoptosis
    • Liu, X. S., Zou, H., Slaughter, C., and Wang, X. D. (1997) DFF: a heterodimeric protein that functions downstream of caspase-3 to trigger DNA fragmentation during apoptosis. Cell 89, 175-184
    • (1997) Cell , vol.89 , pp. 175-184
    • Liu, X.S.1    Zou, H.2    Slaughter, C.3    Wang, X.D.4
  • 13
    • 0031888955 scopus 로고    scopus 로고
    • A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD
    • Enari, M., Sakahira, H., Yokoyama, H., Okawa, K., Iwamatsu, A., and Nagata, S. (1998) A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD. Nature (London) 391, 43-50
    • (1998) Nature (London) , vol.391 , pp. 43-50
    • Enari, M.1    Sakahira, H.2    Yokoyama, H.3    Okawa, K.4    Iwamatsu, A.5    Nagata, S.6
  • 14
    • 0026648674 scopus 로고
    • Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation
    • Gavrieli, Y., Sherman, Y., and Ben-Sasson, S. A. (1992) Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation. J. Cell Biol. 119, 493-501
    • (1992) J. Cell Biol. , vol.119 , pp. 493-501
    • Gavrieli, Y.1    Sherman, Y.2    Ben-Sasson, S.A.3
  • 15
    • 0030943111 scopus 로고    scopus 로고
    • Early detection of DNA strand breaks in the brain after transient focal ischemia: Implications for the role of DNA damage in apoptosis and neuronal cell death
    • Chen, J., Jin K., Chen, M., Pei, W., Kawaguchi, K., Greenberg, D. A., and Simon R. P. (1997) Early detection of DNA strand breaks in the brain after transient focal ischemia: implications for the role of DNA damage in apoptosis and neuronal cell death. J. Neurochem. 69, 232-245
    • (1997) J. Neurochem. , vol.69 , pp. 232-245
    • Chen, J.1    Jin, K.2    Chen, M.3    Pei, W.4    Kawaguchi, K.5    Greenberg, D.A.6    Simon R, P.7
  • 16
    • 0027942138 scopus 로고
    • The NOS inhibitor, 7-nitroindazole, decreases focal infract volume but not the response to topical acetylcholine in pial vessels
    • Yoshida, T., Limmroth, V., Irikura, K., and Moskowitz, M. A. (1994) The NOS inhibitor, 7-nitroindazole, decreases focal infract volume but not the response to topical acetylcholine in pial vessels. J. Cereb. Blood Flow Metab. 14, 924-929
    • (1994) J. Cereb. Blood Flow Metab. , vol.14 , pp. 924-929
    • Yoshida, T.1    Limmroth, V.2    Irikura, K.3    Moskowitz, M.A.4
  • 19
    • 0030605974 scopus 로고    scopus 로고
    • Neuroprotective of 7-nitroindazole in the gerbil model of global cerebral ischemia
    • O'Neill, M. J., Hicks, C., and Ward, M. (1996) Neuroprotective of 7-nitroindazole in the gerbil model of global cerebral ischemia. Eur. J. Pharmacol. 310, 115-122
    • (1996) Eur. J. Pharmacol. , vol.310 , pp. 115-122
    • O'Neill, M.J.1    Hicks, C.2    Ward, M.3
  • 20
    • 0030839865 scopus 로고    scopus 로고
    • Oxidative decay of DNA
    • Beckman, K. B., and Ames, B. N. (1997) Oxidative decay of DNA. J. Biol Chem. 272, 19633-19636
    • (1997) J. Biol Chem. , vol.272 , pp. 19633-19636
    • Beckman, K.B.1    Ames, B.N.2
  • 21
    • 0033968085 scopus 로고    scopus 로고
    • Up-regulation of base excision repair activity for 8-2′ deoxyhydroxyl guanosine in the mouse brain after forebrain ischemia-reperfusion
    • Lin, L., Cao, S., Yu, L., Cui, J., Hamilton, W. J., and Liu, P. K. (2000) Up-regulation of base excision repair activity for 8-2′ deoxyhydroxyl guanosine in the mouse brain after forebrain ischemia-reperfusion. J. Neurochem. 74, 101-108
    • (2000) J. Neurochem. , vol.74 , pp. 101-108
    • Lin, L.1    Cao, S.2    Yu, L.3    Cui, J.4    Hamilton, W.J.5    Liu, P.K.6
  • 24
    • 0028596398 scopus 로고
    • Transcription-coupled repair and human disease
    • Hanawalt, P.C. ( 1994) Transcription-coupled repair and human disease. Science 266, 1957-1958
    • (1994) Science , vol.266 , pp. 1957-1958
    • Hanawalt, P.C.1
  • 26
    • 0031032817 scopus 로고    scopus 로고
    • Mitochondrial DNA damage is more extensive and persists longer than nuclear DNA damage in human cells following oxidative stress
    • Yakes, F. M., and Van Houten, B. (1997) Mitochondrial DNA damage is more extensive and persists longer than nuclear DNA damage in human cells following oxidative stress. Proc. Natl. Acad. Sci. USA 94, 514-519
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 514-519
    • Yakes, F.M.1    Van Houten, B.2
  • 28
    • 0025373259 scopus 로고
    • Oxidative damage to DNA during aging: 8-hydroxy-2′-deoxyguanosine in rat organ DNA and urine
    • Fraga, C. G., Shigenaga, M. K., Park, J-W., Degan, P., and Ames, B. N. (1990) Oxidative damage to DNA during aging: 8-hydroxy-2′-deoxyguanosine in rat organ DNA and urine. Proc. Natl. Acad. Sci. USA 87, 4533-4537
    • (1990) Proc. Natl. Acad. Sci. USA , vol.87 , pp. 4533-4537
    • Fraga, C.G.1    Shigenaga, M.K.2    Park, J.-W.3    Degan, P.4    Ames, B.N.5
  • 29
    • 0033559462 scopus 로고    scopus 로고
    • RNA oxidation is a prominent feature of vulnerable neurons in Alzheimer's disease
    • Nunomura, A., Perry, G., Pappolla, M. A., Wade, R., Hirai, K., Chiba, S., and Smith, M. A. (1999) RNA oxidation is a prominent feature of vulnerable neurons in Alzheimer's disease. J. Neurosci. 19, 1959-1964
    • (1999) J. Neurosci. , vol.19 , pp. 1959-1964
    • Nunomura, A.1    Perry, G.2    Pappolla, M.A.3    Wade, R.4    Hirai, K.5    Chiba, S.6    Smith, M.A.7
  • 30
    • 0344298999 scopus 로고    scopus 로고
    • Immunohistochemical detection of oxidative DNA damage induced by ischemia-reperfusion insults in gerbil hippocampus in vivo
    • Won, M. H., Kang, T. C., Jeon, G. S., Lee, J. C., Kim, D. Y., Choi, E. M., Lee, K. H., Choi, C. D., Chung, M. H., and Cho, S. S. (1999) Immunohistochemical detection of oxidative DNA damage induced by ischemia-reperfusion insults in gerbil hippocampus in vivo. Brain Res. 836, 70-78
    • (1999) Brain Res. , vol.836 , pp. 70-78
    • Won, M.H.1    Kang, T.C.2    Jeon, G.S.3    Lee, J.C.4    Kim, D.Y.5    Choi, E.M.6    Lee, K.H.7    Choi, C.D.8    Chung, M.H.9    Cho, S.S.10
  • 31
    • 0026533905 scopus 로고
    • Substrate specificity of the Escherichia coli Fpg protein (formamidopyrimidine-DNA glycoslyase): Excision of purine lesions in DNA produced by ionizing radiation or photosensitization
    • Boiteux, S., Gajewski, E., Laval, J., and Dizdaroglu, M. (1992) Substrate specificity of the Escherichia coli Fpg protein (formamidopyrimidine-DNA glycoslyase): excision of purine lesions in DNA produced by ionizing radiation or photosensitization. Biochemistry 31, 106-110
    • (1992) Biochemistry , vol.31 , pp. 106-110
    • Boiteux, S.1    Gajewski, E.2    Laval, J.3    Dizdaroglu, M.4
  • 32
    • 0022545394 scopus 로고
    • A model of focal ischemic stroke in the rat: Reproducible extensive cortical infarction
    • Chen, S. T., Hsu, C. Y., Hogan, E. L., Maricq, H., and Balentine, J. D. (1986) A model of focal ischemic stroke in the rat: reproducible extensive cortical infarction. Stroke 17, 738-743
    • (1986) Stroke , vol.17 , pp. 738-743
    • Chen, S.T.1    Hsu, C.Y.2    Hogan, E.L.3    Maricq, H.4    Balentine, J.D.5
  • 33
    • 0024571782 scopus 로고
    • Polyethylene glycol-conjugated superoxide dismutase and catalase reduce ischemic brain injury
    • Liu, T. H., Beckman, J. S., Freeman, B. A., Hogan, E. L., and Hsu C. Y. (1989) Polyethylene glycol-conjugated superoxide dismutase and catalase reduce ischemic brain injury. Am. J. Physiol. 256, H589-H593
    • (1989) Am. J. Physiol. , vol.256
    • Liu, T.H.1    Beckman, J.S.2    Freeman, B.A.3    Hogan, E.L.4    Hsu, C.Y.5
  • 34
    • 0027283310 scopus 로고
    • Expression of c-fos and c-jun family genes after focal cerebral ischemia
    • An, G., Lin, T. N., Liu, J. S., Xue, J. J., He, Y. Y., and Hsu, C. Y. (1993) Expression of c-fos and c-jun family genes after focal cerebral ischemia. Ann. Neurol. 33, 457-464
    • (1993) Ann. Neurol. , vol.33 , pp. 457-464
    • An, G.1    Lin, T.N.2    Liu, J.S.3    Xue, J.J.4    He, Y.Y.5    Hsu, C.Y.6
  • 35
    • 0028170006 scopus 로고
    • Suppression of ischemia-induced Fos expression and AP-1 activity by an antisense oligodeoxynucleotide to c-fos mRNA
    • Liu, P. K., Salminen, A., He, Y., Jiang, M. H., Xue, J. J., Liu, J. S., and Hsu, C. Y. (1994) Suppression of ischemia-induced Fos expression and AP-1 activity by an antisense oligodeoxynucleotide to c-fos mRNA. Ann. Neurol. 36, 566-576
    • (1994) Ann. Neurol. , vol.36 , pp. 566-576
    • Liu, P.K.1    Salminen, A.2    He, Y.3    Jiang, M.H.4    Xue, J.J.5    Liu, J.S.6    Hsu, C.Y.7
  • 36
    • 0343662589 scopus 로고
    • Exonuclease III
    • W. H. Freeman, San Francisco
    • Kornberg, A. (1980) Exonuclease III. In DNA Replication, pp. 324-327, W. H. Freeman, San Francisco
    • (1980) DNA Replication , pp. 324-327
    • Kornberg, A.1
  • 37
    • 0025191508 scopus 로고
    • Nuclear magnetic resonance studies on the tautomerism of 8-hydroxy-2′-deoxyguanosine, 8-hydroxyguanosine and c8-substituted guanine nucleosides
    • Cho, B. P., Kadlubar, F. F., Culp, S. J., and Evans, F. E. (1990) Nuclear magnetic resonance studies on the tautomerism of 8-hydroxy-2′-deoxyguanosine, 8-hydroxyguanosine and C8-substituted guanine nucleosides. Chem. Res. Toxicol. 3, 445-452
    • (1990) Chem. Res. Toxicol. , vol.3 , pp. 445-452
    • Cho, B.P.1    Kadlubar, F.F.2    Culp, S.J.3    Evans, F.E.4
  • 38
    • 0025981824 scopus 로고
    • Structure of oxidatively damaged nucleic acid adducts: Tautomerism, ionization and protonation of 8-hydroxy adenosine study by NMR spectroscopy
    • Cho, B. P., and Evans, F. E. (1991) Structure of oxidatively damaged nucleic acid adducts: tautomerism, ionization and protonation of 8-hydroxy adenosine study by NMR spectroscopy. Nucleic Acids Res. 19, 1041-1047
    • (1991) Nucleic Acids Res. , vol.19 , pp. 1041-1047
    • Cho, B.P.1    Evans, F.E.2
  • 39
    • 78651158488 scopus 로고
    • Antibodies specific for ribonucleosides and ribonucleotides and their reaction with DNA
    • Erlanger, B. F., and Beiser, S. M. (1964) Antibodies specific for ribonucleosides and ribonucleotides and their reaction with DNA. Proc. Natl. Acad. Sci. USA 52, 68-74
    • (1964) Proc. Natl. Acad. Sci. USA , vol.52 , pp. 68-74
    • Erlanger, B.F.1    Beiser, S.M.2
  • 40
    • 0026568631 scopus 로고
    • Assay of excised oxidative DNA lesions: Isolation of 8-oxoguanine and ils nucleoside derivatives from biological fluids with a monoclonal antibody column
    • Park, E-M., Shigenaga, M. K., Degan, P., Korn, T. S., Kitzler, J. W., Wehr, C. M., Kolachana, P., and Ames, B. N. (1992) Assay of excised oxidative DNA lesions: isolation of 8-oxoguanine and ils nucleoside derivatives from biological fluids with a monoclonal antibody column. Proc. Natl. Acad. Sci. USA 89, 3375-3379
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 3375-3379
    • Park, E.-M.1    Shigenaga, M.K.2    Degan, P.3    Korn, T.S.4    Kitzler, J.W.5    Wehr, C.M.6    Kolachana, P.7    Ames, B.N.8
  • 41
    • 0030047274 scopus 로고    scopus 로고
    • Very delayed infraction after middle focal cerebral ischemia: A role for apoptosis?
    • Du, C., Hu, R., Csernansky, C. A., Hsu, C. Y., and Choi, D. W. (1996) Very delayed infraction after middle focal cerebral ischemia: a role for apoptosis? J. Cereb. Blood Flow Metab. 16, 195-201
    • (1996) J. Cereb. Blood Flow Metab. , vol.16 , pp. 195-201
    • Du, C.1    Hu, R.2    Csernansky, C.A.3    Hsu, C.Y.4    Choi, D.W.5
  • 42
    • 0027272975 scopus 로고
    • Spectrum of spontaneous mutation in animal cells containing an aphidicolin-resistant DNA polymerase-a
    • Liu, P. K., Trujillo, J. M., and Monnat, R. J. (1993) Spectrum of spontaneous mutation in animal cells containing an aphidicolin-resistant DNA polymerase-a. Mutation Res. 288, 229-236
    • (1993) Mutation Res. , vol.288 , pp. 229-236
    • Liu, P.K.1    Trujillo, J.M.2    Monnat, R.J.3
  • 43
    • 0030247006 scopus 로고    scopus 로고
    • Mixed signals in Alzheimer's disease
    • Neve, R. L. (1996) Mixed signals in Alzheimer's disease. Trends Neurosci. 19, 371-372
    • (1996) Trends Neurosci. , vol.19 , pp. 371-372
    • Neve, R.L.1
  • 44
    • 0026635461 scopus 로고
    • Oxidative stress as a cause of nigral cell death in Parkinson's disease and incidental Lewy body disease
    • Jenner, P., Dexter, D. T., Sian, J., Schapira, A. H., and Marsden, C. D. (1992) Oxidative stress as a cause of nigral cell death in Parkinson's disease and incidental Lewy body disease. Ann. Neurol. 32, S82-87
    • (1992) Ann. Neurol. , vol.32
    • Jenner, P.1    Dexter, D.T.2    Sian, J.3    Schapira, A.H.4    Marsden, C.D.5
  • 46
    • 0027686249 scopus 로고
    • Oxidative stress, glutamate, and neurodegenerative disorders
    • Coyle, J. T., and Puttfarcken, P. (1993) Oxidative stress, glutamate, and neurodegenerative disorders. Science 262, 689-694
    • (1993) Science , vol.262 , pp. 689-694
    • Coyle, J.T.1    Puttfarcken, P.2
  • 47
    • 0031975026 scopus 로고    scopus 로고
    • Response of postmitotic neurons to x-irradiation: Implications for the role of DNA damage in neuronal apoptosis
    • Gobbel, G. T., Bellinzona, M., Vogt, A. R., Gupta, N., Fike, J. R., and Chan, P. (1998) Response of postmitotic neurons to x-irradiation: implications for the role of DNA damage in neuronal apoptosis. J. Neurosci. 18, 147-155
    • (1998) J. Neurosci. , vol.18 , pp. 147-155
    • Gobbel, G.T.1    Bellinzona, M.2    Vogt, A.R.3    Gupta, N.4    Fike, J.R.5    Chan, P.6
  • 48
    • 0033557658 scopus 로고    scopus 로고
    • Suppression of post-ischemic hippocampal NGF expression by a c-fos antisense ODN
    • Cui, J. K., Hsu, C. Y., and Liu, P. K. (1999) Suppression of post-ischemic hippocampal NGF expression by a c-fos antisense ODN. J. Neurosci. 19, 1335-1344
    • (1999) J. Neurosci. , vol.19 , pp. 1335-1344
    • Cui, J.K.1    Hsu, C.Y.2    Liu, P.K.3
  • 49
    • 0029834603 scopus 로고    scopus 로고
    • Immediate early gene expression in response to cerebral ischemia: Friend or foe?
    • Akins, P. T., Liu, P. K., and Hsu, C. Y. (1996) Immediate early gene expression in response to cerebral ischemia: friend or foe? Stroke 27, 1682-1687
    • (1996) Stroke , vol.27 , pp. 1682-1687
    • Akins, P.T.1    Liu, P.K.2    Hsu, C.Y.3
  • 50
    • 0028170006 scopus 로고
    • Suppression of ischemia-induced Fos expression and AP-1 activity by an antisense oligodeoxynucleotide to c-fos mRNA
    • Liu, P. K., Salminen, A., He, Y. Y., Jiang, M. H., Xue, J. J., Liu, J. S., and Hsu, C. Y. (1994) Suppression of ischemia-induced Fos expression and AP-1 activity by an antisense oligodeoxynucleotide to c-fos mRNA. Ann. Neurol. 36, 566-576
    • (1994) Ann. Neurol. , vol.36 , pp. 566-576
    • Liu, P.K.1    Salminen, A.2    He, Y.Y.3    Jiang, M.H.4    Xue, J.J.5    Liu, J.S.6    Hsu, C.Y.7
  • 52
    • 0030570517 scopus 로고    scopus 로고
    • Oxidative DNA damage in human respiratory tract epithelial cells: Time course in relation to DNA strand breakage
    • Spencer, J. P., Jenner, A., Aruoma, O. I., Cross, C. E., Wu, R., and Halliwell, B. (1996) Oxidative DNA damage in human respiratory tract epithelial cells: time course in relation to DNA strand breakage. Biochem. Biophys. Res. Commun. 224, 17-22
    • (1996) Biochem. Biophys. Res. Commun. , vol.224 , pp. 17-22
    • Spencer, J.P.1    Jenner, A.2    Aruoma, O.I.3    Cross, C.E.4    Wu, R.5    Halliwell, B.6
  • 53
    • 0020354447 scopus 로고
    • Sites and structure of gamma radiation-induced DNA strand breaks
    • Henner, W. D., Grunberg, S. M., and Haseltine, W. A. (1982) Sites and structure of gamma radiation-induced DNA strand breaks. J. Biol. Chem. 257, 11750-11754
    • (1982) J. Biol. Chem. , vol.257 , pp. 11750-11754
    • Henner, W.D.1    Grunberg, S.M.2    Haseltine, W.A.3
  • 54
    • 0029875519 scopus 로고    scopus 로고
    • Repair of products of oxidative DNA base damage in human cells
    • Jaruga, P., and Dizdaroglu, M. (1996) Repair of products of oxidative DNA base damage in human cells. Nucleic Acids Res. 24, 1389-94
    • (1996) Nucleic Acids Res. , vol.24 , pp. 1389-1394
    • Jaruga, P.1    Dizdaroglu, M.2
  • 55
    • 0033000268 scopus 로고    scopus 로고
    • Temporal patterns of poly(ADP-ribose) polymerase activation in the cortex following experimental brain injury in the rat
    • LaPlaca, M. C., Raghupathi, R., Verma, A., Pieper, A. A., Saatman, K. E., Snyder, S. H., and McIntosh, T. K. (1999) Temporal patterns of poly(ADP-ribose) polymerase activation in the cortex following experimental brain injury in the rat. J. Neurochem. 73, 205-213
    • (1999) J. Neurochem. , vol.73 , pp. 205-213
    • LaPlaca, M.C.1    Raghupathi, R.2    Verma, A.3    Pieper, A.A.4    Saatman, K.E.5    Snyder, S.H.6    McIntosh, T.K.7
  • 56
    • 0029944285 scopus 로고    scopus 로고
    • Fluorescence light-induced chromatid breaks distinguish Alzheimer disease cells from normal cells in tissue culture
    • Parshad, R., Sanford, K. K., and Price, F. M. (1996) Fluorescence light-induced chromatid breaks distinguish Alzheimer disease cells from normal cells in tissue culture. Proc. Natl. Acad. Sci. USA 93, 5146-5150
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 5146-5150
    • Parshad, R.1    Sanford, K.K.2    Price, F.M.3
  • 57
    • 0021019873 scopus 로고
    • Iron and oxygen radicals in tissue damage: Implications for the neuronal ceroid lipofuscinoses
    • Gutteridge, J. M., Westermarck, T., and Santavvori, P. (1983) Iron and oxygen radicals in tissue damage: implications for the neuronal ceroid lipofuscinoses. J. Acta Neurol. Scand. 68, 365-370
    • (1983) J. Acta Neurol. Scand. , vol.68 , pp. 365-370
    • Gutteridge, J.M.1    Westermarck, T.2    Santavvori, P.3
  • 58
    • 0028900092 scopus 로고
    • Involvement of free radicals in excitotoxicity in vivo
    • Schulz, J. B., Henshow, D. R., and Siwek, D. (1995) Involvement of free radicals in excitotoxicity in vivo. J. Neurochem. 64, 2239-2247
    • (1995) J. Neurochem. , vol.64 , pp. 2239-2247
    • Schulz, J.B.1    Henshow, D.R.2    Siwek, D.3
  • 59
    • 0024589421 scopus 로고
    • Central nervous system trauma and stroke. II. Physiological and pharmacological evidence for involvement of oxygen radicals and lipid peroxidation
    • Hall, E. D., and Braughler, J. M. (1989) Central nervous system trauma and stroke. II. Physiological and pharmacological evidence for involvement of oxygen radicals and lipid peroxidation. Free Rad. Med. Biol. 6, 303-313
    • (1989) Free Rad. Med. Biol. , vol.6 , pp. 303-313
    • Hall, E.D.1    Braughler, J.M.2
  • 60
    • 0026602663 scopus 로고
    • Prevention of post-ischemic brain lipid conjugated diene production and neurological injury by hydroxyethylstarch-conjugated deferoxamine
    • Rosenthal, R. E., Chanderbahn, R., Marshall, G., and Fiskum, G. (1992) Prevention of post-ischemic brain lipid conjugated diene production and neurological injury by hydroxyethylstarch-conjugated deferoxamine. Free Rad. Biol. Med. 12, 29-33
    • (1992) Free Rad. Biol. Med. , vol.12 , pp. 29-33
    • Rosenthal, R.E.1    Chanderbahn, R.2    Marshall, G.3    Fiskum, G.4
  • 61
    • 0020308323 scopus 로고
    • Parkinson's disease: A disorder due to nigral glutathione deficiency
    • Perry, T. L., Godin, D. V., and Hansen, S. (1982) Parkinson's disease: a disorder due to nigral glutathione deficiency. Neurosci. Lett. 33, 305-310
    • (1982) Neurosci. Lett. , vol.33 , pp. 305-310
    • Perry, T.L.1    Godin, D.V.2    Hansen, S.3
  • 63
    • 0030916372 scopus 로고    scopus 로고
    • Evidence of reduced DNA repair in amyotrophic lateral sclerosis brain tissue
    • Kisby, G. E., Milne, J., and Sweatt, C. (1997) Evidence of reduced DNA repair in amyotrophic lateral sclerosis brain tissue. Neuroreport 8, 1337-1340
    • (1997) Neuroreport , vol.8 , pp. 1337-1340
    • Kisby, G.E.1    Milne, J.2    Sweatt, C.3
  • 64
    • 0025285843 scopus 로고
    • The molecular basis of brain injury and brain edema: The role of oxygen free radicals
    • Ikeda, Y., and Long, D. L. (1990) The molecular basis of brain injury and brain edema: the role of oxygen free radicals. Neurosurgery 27, 1-11
    • (1990) Neurosurgery , vol.27 , pp. 1-11
    • Ikeda, Y.1    Long, D.L.2
  • 66
    • 0001885914 scopus 로고    scopus 로고
    • Prokaryotic base excision repair
    • Nickoloff, J. A. and Hoekstra, M F., eds Hamana Press, Totowa, N.J.
    • Wilson, D. M., Engelwood, B. P., and Samson, L. (1998) Prokaryotic base excision repair, In DNA Damage and Repair (Nickoloff, J. A. and Hoekstra, M F., eds) Vol. 1, pp. 29-64, Hamana Press, Totowa, N.J.
    • (1998) DNA Damage and Repair , vol.1 , pp. 29-64
    • Wilson, D.M.1    Engelwood, B.P.2    Samson, L.3


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