E2F1 mediates death of B-amyloid-treated cortical neurons in a manner independent of p53 and dependent on Bax and caspase 3

Journal of Biological Chemistry

Volumn 275, Issue 16, 2000, Pages 11553-11560

  Giovanni, Andrew ^a   Keramaris, Elizabeth ^e   Morris, Erick J ^b   Hou, Sheng T ^c   O'Hare, Michael ^e   Dyson, Nick ^b   Robertson, George S ^d   Slack, Ruth S ^e   Park, David S ^e  

^a SANOFI   (France)

^b MASSACHUSETTS GENERAL HOSPITAL CANCER CENTER   (United States)

^c NATIONAL RESEARCH COUNCIL CANADA   (Canada)

^d MERCK FROSST CENTRE FOR THERAPEUTIC RESEARCH   (Canada)

^e UNIVERSITY OF OTTAWA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN; CASPASE 3; PROTEIN BAX; PROTEIN P53; RETINOBLASTOMA PROTEIN; TRANSCRIPTION FACTOR;

ALZHEIMER DISEASE; ANIMAL CELL; ARTICLE; BRAIN CELL; CELL DEATH; ENZYME ACTIVITY; MOUSE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

AMYLOID BETA-PROTEIN; ANIMALS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CARRIER PROTEINS; CASPASE 3; CASPASES; CELL CYCLE PROTEINS; CELLS, CULTURED; CEREBRAL CORTEX; COUMARINS; DNA-BINDING PROTEINS; E2F TRANSCRIPTION FACTORS; E2F1 TRANSCRIPTION FACTOR; ENZYME ACTIVATION; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NEURONS; OLIGOPEPTIDES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2; TRANSCRIPTION FACTOR DP1; TRANSCRIPTION FACTORS; TUMOR SUPPRESSOR PROTEIN P53;

ANIMALIA;

EID: 0034697299     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.275.16.11553     Document Type: Article

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