메뉴 건너뛰기




Volumn 71, Issue 5, 1998, Pages 2034-2040

Increased nuclear DNA oxidation in the brain in Alzheimer' s disease

Author keywords

Alzheimer's disease; DNA oxidation; Gas chromatography mass spectrometry; Oxidative stress

Indexed keywords

CELL NUCLEUS DNA;

EID: 0031754202     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.1998.71052034.x     Document Type: Article
Times cited : (418)

References (39)
  • 1
    • 0028148336 scopus 로고
    • Energy, oxidative damage, Alzheimer's disease: Clues to the underlying puzzle
    • Beal M. F. (1994) Energy, oxidative damage, Alzheimer's disease: clues to the underlying puzzle. Neurobiol. Aging 15, S171-S174.
    • (1994) Neurobiol. Aging , vol.15
    • Beal, M.F.1
  • 2
    • 0030839865 scopus 로고    scopus 로고
    • Oxidative decay of DNA
    • Beckman K. and Ames B. N. (1997) Oxidative decay of DNA. J. Biol. Chem. 272, 19633-19636.
    • (1997) J. Biol. Chem. , vol.272 , pp. 19633-19636
    • Beckman, K.1    Ames, B.N.2
  • 3
    • 0031800225 scopus 로고    scopus 로고
    • Imbalances of trace elements related to oxidative damage in Alzheimer's disease brains
    • Cornett C. R., Markesbery W. R., and Ehmann W. D. (1998) Imbalances of trace elements related to oxidative damage in Alzheimer's disease brains. Neurotoxicology 19, 339-346.
    • (1998) Neurotoxicology , vol.19 , pp. 339-346
    • Cornett, C.R.1    Markesbery, W.R.2    Ehmann, W.D.3
  • 4
    • 0030297178 scopus 로고    scopus 로고
    • Copper, iron, and zinc imbalances in severely degenerated brain regions in Alzheimer's disease: Possible relation to oxidative stress
    • Diebel M. A., Ehmann W. D., and Markesbery W. R. (1996) Copper, iron, and zinc imbalances in severely degenerated brain regions in Alzheimer's disease: possible relation to oxidative stress. J. Neurol. Sci. 143, 137-142.
    • (1996) J. Neurol. Sci. , vol.143 , pp. 137-142
    • Diebel, M.A.1    Ehmann, W.D.2    Markesbery, W.R.3
  • 5
    • 0027391867 scopus 로고
    • Quantitative determination of oxidative base damage in DNA by stable isotope-dilution mass spectrometry
    • Dizdaroglu M. (1993) Quantitative determination of oxidative base damage in DNA by stable isotope-dilution mass spectrometry. FEBS Lett. 315, 1-6.
    • (1993) FEBS Lett. , vol.315 , pp. 1-6
    • Dizdaroglu, M.1
  • 6
    • 0025869755 scopus 로고
    • Damage to the DNA bases in mammalian chromatin by hydrogen peroxide in the presence of ferric and cupric ions
    • Dizdaroglu M., Rao G., Halliwell B., and Gajewski E. (1991) Damage to the DNA bases in mammalian chromatin by hydrogen peroxide in the presence of ferric and cupric ions. Arch. Biochem. Biophys. 285, 317-324.
    • (1991) Arch. Biochem. Biophys. , vol.285 , pp. 317-324
    • Dizdaroglu, M.1    Rao, G.2    Halliwell, B.3    Gajewski, E.4
  • 7
    • 0029923474 scopus 로고    scopus 로고
    • Observation and prevention of an artifactual formation of oxidized DNA bases and nucleosides in the GC-EIMS method
    • Douki T., Delatour T., Bianchini F., and Cadet J. (1996) Observation and prevention of an artifactual formation of oxidized DNA bases and nucleosides in the GC-EIMS method. Carcinogenesis 17, 347-353.
    • (1996) Carcinogenesis , vol.17 , pp. 347-353
    • Douki, T.1    Delatour, T.2    Bianchini, F.3    Cadet, J.4
  • 9
    • 0026573467 scopus 로고
    • Selective accumulation of aluminum and iron in neurofibrillary tangles of Alzheimer's disease: A laser microprobe (LAMMA) study
    • Good P. F., Perl D. P., Bierer L. M., and Schmeidler J. (1992) Selective accumulation of aluminum and iron in neurofibrillary tangles of Alzheimer's disease: a laser microprobe (LAMMA) study. Ann. Neurol. 31, 286-292.
    • (1992) Ann. Neurol. , vol.31 , pp. 286-292
    • Good, P.F.1    Perl, D.P.2    Bierer, L.M.3    Schmeidler, J.4
  • 10
    • 0029902166 scopus 로고    scopus 로고
    • Evidence for neuronal oxidative damage in Alzheimer's disease
    • Good P. F., Werner P., Hsu A., Olanow C. W., and Perl D. P. (1996) Evidence for neuronal oxidative damage in Alzheimer's disease. Am. J. Pathol. 149, 21-28.
    • (1996) Am. J. Pathol. , vol.149 , pp. 21-28
    • Good, P.F.1    Werner, P.2    Hsu, A.3    Olanow, C.W.4    Perl, D.P.5
  • 11
    • 0025069762 scopus 로고
    • How to characterize a biological antioxidant
    • Halliwell B. (1990) How to characterize a biological antioxidant. Free Radic. Res. Commun. 9, 1-32.
    • (1990) Free Radic. Res. Commun. , vol.9 , pp. 1-32
    • Halliwell, B.1
  • 12
    • 0026456852 scopus 로고
    • The measurement of oxidative damage to DNA by HPLC and GC/MS techniques
    • Halliwell B. and Dizdaroglu M. (1992) The measurement of oxidative damage to DNA by HPLC and GC/MS techniques. Free Radic. Res. Commun. 16, 75-87.
    • (1992) Free Radic. Res. Commun. , vol.16 , pp. 75-87
    • Halliwell, B.1    Dizdaroglu, M.2
  • 14
    • 0026501562 scopus 로고
    • Kunitz protease inhibitor-containing amyloid β protein precursor immunoreactivity in Alzheimer's disease
    • Hyman B. T., Tanzi R. E., Marzloff K., Barbour R., and Schenk D. (1992) Kunitz protease inhibitor-containing amyloid β protein precursor immunoreactivity in Alzheimer's disease. J. Neuropathol. Exp. Neurol. 51, 76-83.
    • (1992) J. Neuropathol. Exp. Neurol. , vol.51 , pp. 76-83
    • Hyman, B.T.1    Tanzi, R.E.2    Marzloff, K.3    Barbour, R.4    Schenk, D.5
  • 15
    • 0029073455 scopus 로고
    • Elevated thiobarbituric acid-reactive substances and antioxidant enzyme activity in the brain in Alzheimer's disease
    • Lovell M. A., Ehmann W. D., Butler S. M., and Markesbery W. R. (1995) Elevated thiobarbituric acid-reactive substances and antioxidant enzyme activity in the brain in Alzheimer's disease. Neurology 45, 1594-1601.
    • (1995) Neurology , vol.45 , pp. 1594-1601
    • Lovell, M.A.1    Ehmann, W.D.2    Butler, S.M.3    Markesbery, W.R.4
  • 16
    • 0030714092 scopus 로고    scopus 로고
    • Elevated 4-hydroxynonenal in ventricular fluid in Alzheimer's disease
    • Lovell M. A., Ehmann W. D., Mattson M. P., and Markesbery W. R. (1997) Elevated 4-hydroxynonenal in ventricular fluid in Alzheimer's disease. Neurobiol. Aging 18, 457-461.
    • (1997) Neurobiol. Aging , vol.18 , pp. 457-461
    • Lovell, M.A.1    Ehmann, W.D.2    Mattson, M.P.3    Markesbery, W.R.4
  • 18
    • 0030898724 scopus 로고    scopus 로고
    • An assessment of oxidative damage to proteins, lipids, and DNA in brain from patients with Alzheimer's disease
    • Lyras L., Cairns N. J., Jenner A., Jenner P., and Halliwell B. (1997) An assessment of oxidative damage to proteins, lipids, and DNA in brain from patients with Alzheimer's disease. J. Neurochem. 68, 2061-2069.
    • (1997) J. Neurochem. , vol.68 , pp. 2061-2069
    • Lyras, L.1    Cairns, N.J.2    Jenner, A.3    Jenner, P.4    Halliwell, B.5
  • 19
    • 0030915855 scopus 로고    scopus 로고
    • Oxidative stress hypothesis in Alzheimer's disease
    • Markesbery W. R. (1997) Oxidative stress hypothesis in Alzheimer's disease. Free Radic. Biol. Med. 23, 134-147.
    • (1997) Free Radic. Biol. Med. , vol.23 , pp. 134-147
    • Markesbery, W.R.1
  • 20
    • 0031980065 scopus 로고    scopus 로고
    • Four-hydroxynonenal, a product of lipid peroxidation, is increased in the brain in Alzheimer's disease
    • Markesbery W. R. and Lovell M. A. (1998) Four-hydroxynonenal, a product of lipid peroxidation, is increased in the brain in Alzheimer's disease. Neurobiol. Aging 19, 33-36.
    • (1998) Neurobiol. Aging , vol.19 , pp. 33-36
    • Markesbery, W.R.1    Lovell, M.A.2
  • 21
    • 0345513785 scopus 로고
    • Clinical diagnosis of Alzheimer's disease: Report of the NINCDS-ADRDA Work Group under the auspices of the Department of Health and Human Services Task Force on Alzheimer's disease
    • McKhann G. D., Drachman D. A., Holstein M. F., Katzman R., Price D., and Stadlan E. M. (1991) Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of the Department of Health and Human Services Task Force on Alzheimer's disease. Neurology 41, 479-486.
    • (1991) Neurology , vol.41 , pp. 479-486
    • McKhann, G.D.1    Drachman, D.A.2    Holstein, M.F.3    Katzman, R.4    Price, D.5    Stadlan, E.M.6
  • 23
    • 0028152717 scopus 로고
    • Oxidative damage to mitochondrial DNA is increased in Alzheimer's disease
    • Mecocci P., MacGarvey U., and Beal M. F. (1994) Oxidative damage to mitochondrial DNA is increased in Alzheimer's disease. Ann. Neurol. 36, 747-751.
    • (1994) Ann. Neurol. , vol.36 , pp. 747-751
    • Mecocci, P.1    MacGarvey, U.2    Beal, M.F.3
  • 25
    • 0025908356 scopus 로고
    • The Consortium to Establish a Registry for Alzheimer's Disease (CERAD). II. Standardization of the neuropathologic assessment of Alzheimer's disease
    • Mirra S. S., Heyman A., McKeel D., Sumi S. M., Cram B. J., Brownlee L. M., Vogel F. S., Hughes J. P., Van Belle G., and Berg L. (1991) The Consortium to Establish a Registry for Alzheimer's Disease (CERAD). II. Standardization of the neuropathologic assessment of Alzheimer's disease. Neurology 41, 479-486.
    • (1991) Neurology , vol.41 , pp. 479-486
    • Mirra, S.S.1    Heyman, A.2    McKeel, D.3    Sumi, S.M.4    Cram, B.J.5    Brownlee, L.M.6    Vogel, F.S.7    Hughes, J.P.8    Van Belle, G.9    Berg, L.10
  • 26
    • 0030040310 scopus 로고    scopus 로고
    • E-4-Hydroxy-2-nonenal is cytotoxic and cross-links cytoskeletal proteins in P19 neuroglial cultures
    • Montine T. J., Amarnath V., Martin M. E., Strittmatter W. J., and Graham D. G. (1996) E-4-Hydroxy-2-nonenal is cytotoxic and cross-links cytoskeletal proteins in P19 neuroglial cultures. Am. J. Pathol. 184, 89-93.
    • (1996) Am. J. Pathol. , vol.184 , pp. 89-93
    • Montine, T.J.1    Amarnath, V.2    Martin, M.E.3    Strittmatter, W.J.4    Graham, D.G.5
  • 27
    • 0030681215 scopus 로고    scopus 로고
    • Consensus recommendations for the postmortem diagnosis of Alzheimer's disease
    • National Institute on Aging and the Reagan Institute Working Group on Diagnostic Criteria for the Neuropathological Assessment of Alzheimer's Disease (1997) Consensus recommendations for the postmortem diagnosis of Alzheimer's disease. Neurobiol. Aging 18, S1-S2.
    • (1997) Neurobiol. Aging , vol.18
  • 29
    • 0028889564 scopus 로고
    • Determination of 8-oxoguanine by gas chromatography-mass spectrometry and HPLC-electrochemical detection: Over-estimation of the background level of the oxidized base by the gas chromatography-mass spectrometry assay
    • Ravanat J., Turesky R. J., Gremaud E., Trudel L. J., and Stadler R. H. (1995) Determination of 8-oxoguanine by gas chromatography-mass spectrometry and HPLC-electrochemical detection: over-estimation of the background level of the oxidized base by the gas chromatography-mass spectrometry assay. Chem. Res. Toxicol. 8, 1039-1045.
    • (1995) Chem. Res. Toxicol. , vol.8 , pp. 1039-1045
    • Ravanat, J.1    Turesky, R.J.2    Gremaud, E.3    Trudel, L.J.4    Stadler, R.H.5
  • 31
    • 0030989545 scopus 로고    scopus 로고
    • 4-Hydroxynonenal-derived advanced lipid peroxidation end products are increased in Alzheimer's disease
    • Sayre L. M., Zelasko D. A., Harris P. L. R., Perry G., Salomon R. G., and Smith M. A. (1997) 4-Hydroxynonenal-derived advanced lipid peroxidation end products are increased in Alzheimer's disease. J. Neurochem. 68, 2092-2097.
    • (1997) J. Neurochem. , vol.68 , pp. 2092-2097
    • Sayre, L.M.1    Zelasko, D.A.2    Harris, P.L.R.3    Perry, G.4    Salomon, R.G.5    Smith, M.A.6
  • 35
    • 0346386580 scopus 로고    scopus 로고
    • Widespread peroxynitrite-mediated damage in Alzheimer's disease
    • Smith M. A., Harris P. L., Sayre L. M., Beckman J. S., and Perry G. (1997a) Widespread peroxynitrite-mediated damage in Alzheimer's disease. J. Neurosci. 17, 2653-2657.
    • (1997) J. Neurosci. , vol.17 , pp. 2653-2657
    • Smith, M.A.1    Harris, P.L.2    Sayre, L.M.3    Beckman, J.S.4    Perry, G.5
  • 36
    • 0030885482 scopus 로고    scopus 로고
    • Iron accumulation in Alzheimer's disease is a source of redox-generated free radicals
    • Smith M. A., Harris P. L., Sayre L. M., and Perry G. (1997b) Iron accumulation in Alzheimer's disease is a source of redox-generated free radicals. Proc. Natl. Acad. Sci. USA 94, 9866-9868.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 9866-9868
    • Smith, M.A.1    Harris, P.L.2    Sayre, L.M.3    Perry, G.4
  • 37
    • 0028157335 scopus 로고
    • Membrane lipids, selectively diminished in Alzheimer brains, suggest synapse loss as a primary event in early-onset form (type 1) and demyelination in late-onset form (type II)
    • Svennerholm L. and Gottfries C. G. (1994) Membrane lipids, selectively diminished in Alzheimer brains, suggest synapse loss as a primary event in early-onset form (type 1) and demyelination in late-onset form (type II). J. Neurochem. 62, 1039-1047.
    • (1994) J. Neurochem. , vol.62 , pp. 1039-1047
    • Svennerholm, L.1    Gottfries, C.G.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.