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Volumn 26, Issue 2, 2006, Pages 207-231

Mechanisms of Allergen-Specific Immunotherapy: T-Regulatory Cells and More

Author keywords

[No Author keywords available]

Indexed keywords

ALLERGEN; ANTIBODY; ANTIGEN; ANTIHISTAMINIC AGENT; ANTITOXIN; AUTOANTIGEN; BACTERIAL ANTIGEN; BEE VENOM; BETA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; CASPASE; COLECALCIFEROL; CORTICOSTEROID; CYTOKINE; DEATH RECEPTOR; DEXAMETHASONE; FOOD ANTIGEN; GRASS POLLEN EXTRACT; HISTAMINE H2 RECEPTOR; IMMUNOGLOBULIN G; INTERLEUKIN 10; INTERLEUKIN 2; LEUKOTRIENE RECEPTOR BLOCKING AGENT; LIPOPOLYSACCHARIDE; TERFENADINE; TRANSFORMING GROWTH FACTOR BETA; TUBERCULIN;

EID: 33646410154     PISSN: 08898561     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.iac.2006.02.008     Document Type: Review
Times cited : (47)

References (180)
  • 1
    • 0005984244 scopus 로고
    • Actively acquired tolerance of foreign cells
    • Billingham R.E., Brent L., and Medawar P.B. Actively acquired tolerance of foreign cells. Nature 172 (1953) 603-606
    • (1953) Nature , vol.172 , pp. 603-606
    • Billingham, R.E.1    Brent, L.2    Medawar, P.B.3
  • 2
    • 0025930522 scopus 로고
    • The Nobel Lectures in Immunology. The Nobel Prize for Physiology or Medicine, 1960. Immunologic recognition of self
    • Burnet F. The Nobel Lectures in Immunology. The Nobel Prize for Physiology or Medicine, 1960. Immunologic recognition of self. Scand J Immunol 33 (1991) 3-13
    • (1991) Scand J Immunol , vol.33 , pp. 3-13
    • Burnet, F.1
  • 4
    • 84910424466 scopus 로고
    • Das Verhalten der kutaanen Tuberkülin-reaktion wahrend der Masern
    • Pirquet V. Das Verhalten der kutaanen Tuberkülin-reaktion wahrend der Masern. Munch Med Wochenschr 34 (1908) 1297-1300
    • (1908) Munch Med Wochenschr , vol.34 , pp. 1297-1300
    • Pirquet, V.1
  • 5
    • 0011869916 scopus 로고
    • Clonal anergy: persistence in tolerant mice of antigen-binding B lymphocytes incapable of responding to antigen or mitogen
    • Nossal G.J., and Pike B.L. Clonal anergy: persistence in tolerant mice of antigen-binding B lymphocytes incapable of responding to antigen or mitogen. Proc Natl Acad Sci USA 77 (1980) 1602-1606
    • (1980) Proc Natl Acad Sci USA , vol.77 , pp. 1602-1606
    • Nossal, G.J.1    Pike, B.L.2
  • 6
    • 0020569052 scopus 로고
    • Induction of tolerance in influenza virus-immune T lymphocyte clones with synthetic peptides of influenza hemagglutinin
    • Lamb J.R., Skidmore B.J., Green N., et al. Induction of tolerance in influenza virus-immune T lymphocyte clones with synthetic peptides of influenza hemagglutinin. J Exp Med 157 (1983) 1434-1447
    • (1983) J Exp Med , vol.157 , pp. 1434-1447
    • Lamb, J.R.1    Skidmore, B.J.2    Green, N.3
  • 7
    • 0028795758 scopus 로고
    • Autocrine T-cell suicide mediated by APO-1(Fas/CD95)
    • Dhein J., Walczak H., Bäumler C., et al. Autocrine T-cell suicide mediated by APO-1(Fas/CD95). Nature 373 (1995) 438-441
    • (1995) Nature , vol.373 , pp. 438-441
    • Dhein, J.1    Walczak, H.2    Bäumler, C.3
  • 8
    • 0028983657 scopus 로고
    • Cell-autonomous Fas (CD95)/Fas-ligand interaction mediates activation-induced apoptosis in T-cell hybridomas
    • Brunner T., Mogil R.J., LaFace D., et al. Cell-autonomous Fas (CD95)/Fas-ligand interaction mediates activation-induced apoptosis in T-cell hybridomas. Nature 373 (1995) 441-444
    • (1995) Nature , vol.373 , pp. 441-444
    • Brunner, T.1    Mogil, R.J.2    LaFace, D.3
  • 9
  • 10
    • 7044286403 scopus 로고    scopus 로고
    • Apoptosis in tissue inflammation and allergic disease
    • Akdis C.A., Blaser K., and Akdis M. Apoptosis in tissue inflammation and allergic disease. Curr Opin Immunol 16 (2004) 717-723
    • (2004) Curr Opin Immunol , vol.16 , pp. 717-723
    • Akdis, C.A.1    Blaser, K.2    Akdis, M.3
  • 11
    • 0033168615 scopus 로고    scopus 로고
    • + T cells respond to superantigen and contribute to eosinophilia and IgE production in atopic dermatitis
    • + T cells respond to superantigen and contribute to eosinophilia and IgE production in atopic dermatitis. J Immunol 163 (1999) 466-475
    • (1999) J Immunol , vol.163 , pp. 466-475
    • Akdis, M.1    Simon, H.-U.2    Weigl, L.3
  • 12
    • 0028804437 scopus 로고
    • Milk-induced eczema is associated with the expansion of T cells expressing cutaneous lymphocyte antigen
    • Abernathy-Carver K.J., Sampson H.A., Picker L.J., et al. Milk-induced eczema is associated with the expansion of T cells expressing cutaneous lymphocyte antigen. J Clin Invest 95 (1995) 913-918
    • (1995) J Clin Invest , vol.95 , pp. 913-918
    • Abernathy-Carver, K.J.1    Sampson, H.A.2    Picker, L.J.3
  • 13
    • 0038108805 scopus 로고    scopus 로고
    • A second step of chemotaxis after transendothelial migration: keratinocytes undergoing apoptosis release IP-10, Mig and iTac for T cell chemotaxis towards epidermis in atopic dermatitis
    • Klunker S., Trautmann A., Akdis M., et al. A second step of chemotaxis after transendothelial migration: keratinocytes undergoing apoptosis release IP-10, Mig and iTac for T cell chemotaxis towards epidermis in atopic dermatitis. J Immunol 171 (2003) 1078-1084
    • (2003) J Immunol , vol.171 , pp. 1078-1084
    • Klunker, S.1    Trautmann, A.2    Akdis, M.3
  • 14
    • 0036467505 scopus 로고    scopus 로고
    • The role of chemokines in linking innate and adaptive immunity
    • Luster A.D. The role of chemokines in linking innate and adaptive immunity. Curr Opin Immunol 14 (2002) 129-135
    • (2002) Curr Opin Immunol , vol.14 , pp. 129-135
    • Luster, A.D.1
  • 15
    • 0033647212 scopus 로고    scopus 로고
    • Non-redundant functional groups of chemokines operate in a coordinate manner during the inflammatory response in the lung
    • Gutierrez-Ramos J.C., Lloyd C., Kapsenberg M.L., et al. Non-redundant functional groups of chemokines operate in a coordinate manner during the inflammatory response in the lung. Immunol Rev 177 (2000) 31-42
    • (2000) Immunol Rev , vol.177 , pp. 31-42
    • Gutierrez-Ramos, J.C.1    Lloyd, C.2    Kapsenberg, M.L.3
  • 16
    • 0038387249 scopus 로고    scopus 로고
    • T helper (Th) 2 predominance in atopic diseases is due to preferential apoptosis of circulating memory/effector Th1 cells
    • Akdis M., Trautmann A., Klunker S., et al. T helper (Th) 2 predominance in atopic diseases is due to preferential apoptosis of circulating memory/effector Th1 cells. FASEB J 17 (2003) 1026-1035
    • (2003) FASEB J , vol.17 , pp. 1026-1035
    • Akdis, M.1    Trautmann, A.2    Klunker, S.3
  • 17
    • 0028878377 scopus 로고
    • Inhibition of programmed eosinophil death: a key pathogenic event for eosinophilia
    • Simon H.-U., and Blaser K. Inhibition of programmed eosinophil death: a key pathogenic event for eosinophilia. Immunol Today 16 (1995) 53-55
    • (1995) Immunol Today , vol.16 , pp. 53-55
    • Simon, H.-U.1    Blaser, K.2
  • 18
    • 0036846875 scopus 로고    scopus 로고
    • Interleukin-13 mediates a fundamental pathway for airway epithelial mucus induced by CD4 T cells and interleukin-9
    • Whittaker L., Niu N., Temann U.A., et al. Interleukin-13 mediates a fundamental pathway for airway epithelial mucus induced by CD4 T cells and interleukin-9. Am J Respir Cell Mol Biol 27 (2002) 593-602
    • (2002) Am J Respir Cell Mol Biol , vol.27 , pp. 593-602
    • Whittaker, L.1    Niu, N.2    Temann, U.A.3
  • 19
    • 0033932896 scopus 로고    scopus 로고
    • T cell-mediated Fas-induced keratinocyte apoptosis plays a key pathogenetic role in eczematous dermatitis
    • Trautmann A., Akdis M., Kleemann D., et al. T cell-mediated Fas-induced keratinocyte apoptosis plays a key pathogenetic role in eczematous dermatitis. J Clin Invest 106 (2000) 25-35
    • (2000) J Clin Invest , vol.106 , pp. 25-35
    • Trautmann, A.1    Akdis, M.2    Kleemann, D.3
  • 20
    • 0036169602 scopus 로고    scopus 로고
    • T cells and eosinophils cooperate in the induction of bronchial epithelial apoptosis in asthma
    • Trautmann A., Schmid-Grendelmeier P., Krüger K., et al. T cells and eosinophils cooperate in the induction of bronchial epithelial apoptosis in asthma. J Allergy Clin Immunol 109 (2002) 329-337
    • (2002) J Allergy Clin Immunol , vol.109 , pp. 329-337
    • Trautmann, A.1    Schmid-Grendelmeier, P.2    Krüger, K.3
  • 21
    • 0035471964 scopus 로고    scopus 로고
    • New insights into the role of T cells in atopic dermatitis and allergic contact dermatitis
    • Trautmann A., Akdis M., Brocker E.B., et al. New insights into the role of T cells in atopic dermatitis and allergic contact dermatitis. Trends Immunol 22 (2001) 530-532
    • (2001) Trends Immunol , vol.22 , pp. 530-532
    • Trautmann, A.1    Akdis, M.2    Brocker, E.B.3
  • 22
    • 0035188843 scopus 로고    scopus 로고
    • Targeting keratinocyte apoptosis in the treatment of atopic dermatitis and allergic contact dermatitis
    • Trautmann A., Akdis M., Schmid-Grendelmeier P., et al. Targeting keratinocyte apoptosis in the treatment of atopic dermatitis and allergic contact dermatitis. J Allergy Clin Immunol 108 (2001) 839-846
    • (2001) J Allergy Clin Immunol , vol.108 , pp. 839-846
    • Trautmann, A.1    Akdis, M.2    Schmid-Grendelmeier, P.3
  • 23
    • 0028288179 scopus 로고
    • Lymphokine production by human T cells in disease states
    • Romagnani S. Lymphokine production by human T cells in disease states. Annu Rev Immunol 12 (1994) 227-257
    • (1994) Annu Rev Immunol , vol.12 , pp. 227-257
    • Romagnani, S.1
  • 24
    • 0029928417 scopus 로고    scopus 로고
    • The expanding universe of T-cell subsets: Th1, Th2 and more
    • Mosmann T.R., and Sad S. The expanding universe of T-cell subsets: Th1, Th2 and more. Immunol Today 17 (1996) 142-146
    • (1996) Immunol Today , vol.17 , pp. 142-146
    • Mosmann, T.R.1    Sad, S.2
  • 25
    • 0031058726 scopus 로고    scopus 로고
    • Interleukin (IL)-6 directs the differentiation of IL-4-producing CD4 + T cells
    • Rincon M., Anguita J., Nakamura T., et al. Interleukin (IL)-6 directs the differentiation of IL-4-producing CD4 + T cells. J Exp Med 185 (1997) 461-469
    • (1997) J Exp Med , vol.185 , pp. 461-469
    • Rincon, M.1    Anguita, J.2    Nakamura, T.3
  • 26
    • 0032749783 scopus 로고    scopus 로고
    • IL-13 in allergy: home at last
    • Corry D.B. IL-13 in allergy: home at last. Curr Opin Immunol 11 (1999) 610-614
    • (1999) Curr Opin Immunol , vol.11 , pp. 610-614
    • Corry, D.B.1
  • 27
    • 0033961847 scopus 로고    scopus 로고
    • Characterization of T cell subpopulations involved in the pathogenesis of asthma and allergic diseases
    • Yssel H., and Groux H. Characterization of T cell subpopulations involved in the pathogenesis of asthma and allergic diseases. Int Arch Allergy Immunol 121 (2000) 10-18
    • (2000) Int Arch Allergy Immunol , vol.121 , pp. 10-18
    • Yssel, H.1    Groux, H.2
  • 28
    • 0042827302 scopus 로고    scopus 로고
    • T cell activation, from atopy to asthma: more a paradox than a paradigm
    • El Biaze M., Boniface S., Koscher V., et al. T cell activation, from atopy to asthma: more a paradox than a paradigm. Allergy 58 (2003) 844-853
    • (2003) Allergy , vol.58 , pp. 844-853
    • El Biaze, M.1    Boniface, S.2    Koscher, V.3
  • 29
    • 0028037782 scopus 로고
    • Regulatory T cell clones induced by oral tolerance: suppression of autoimmune encephalomyelitis
    • Chen Y., Kuchroo V.K., Inobe J., et al. Regulatory T cell clones induced by oral tolerance: suppression of autoimmune encephalomyelitis. Science 265 (1994) 1237-1240
    • (1994) Science , vol.265 , pp. 1237-1240
    • Chen, Y.1    Kuchroo, V.K.2    Inobe, J.3
  • 30
    • 0028179230 scopus 로고
    • low CD4 + T cells are important for the balance between protective and pathogenic cell- mediated immunity
    • low CD4 + T cells are important for the balance between protective and pathogenic cell- mediated immunity. J Exp Med 179 (1994) 589-600
    • (1994) J Exp Med , vol.179 , pp. 589-600
    • Powrie, F.1    Correa-Oliveira, R.2    Mauze, S.3
  • 31
    • 0030704726 scopus 로고    scopus 로고
    • CD4 + T-cell subset inhibits antigen-specific T-cell responses and prevents colitis
    • Groux H., O'Garra A., Bigler M., et al. CD4 + T-cell subset inhibits antigen-specific T-cell responses and prevents colitis. Nature 389 (1997) 737-742
    • (1997) Nature , vol.389 , pp. 737-742
    • Groux, H.1    O'Garra, A.2    Bigler, M.3
  • 32
    • 0032128421 scopus 로고    scopus 로고
    • Role of IL-10 in specific immunotherapy
    • Akdis C.A., Blesken T., Akdis M., et al. Role of IL-10 in specific immunotherapy. J Clin Invest 102 (1998) 98-106
    • (1998) J Clin Invest , vol.102 , pp. 98-106
    • Akdis, C.A.1    Blesken, T.2    Akdis, M.3
  • 33
    • 0035062581 scopus 로고    scopus 로고
    • Human anergic/suppressive CD4(+)CD25(+) T cells: a highly differentiated and apoptosis-prone population
    • Taams L.S., Smith J., Rustin M.H., et al. Human anergic/suppressive CD4(+)CD25(+) T cells: a highly differentiated and apoptosis-prone population. Eur J Immunol 31 (2001) 1122-1131
    • (2001) Eur J Immunol , vol.31 , pp. 1122-1131
    • Taams, L.S.1    Smith, J.2    Rustin, M.H.3
  • 34
    • 0034613767 scopus 로고    scopus 로고
    • Induction of interleukin 10-producing, nonproliferating CD4(+) T cells with regulatory properties by repetitive stimulation with allogeneic immature human dendritic cells
    • Jonuleit H., Schmitt E., Schuler G., et al. Induction of interleukin 10-producing, nonproliferating CD4(+) T cells with regulatory properties by repetitive stimulation with allogeneic immature human dendritic cells. J Exp Med 192 (2000) 1213-1222
    • (2000) J Exp Med , vol.192 , pp. 1213-1222
    • Jonuleit, H.1    Schmitt, E.2    Schuler, G.3
  • 35
    • 0034327264 scopus 로고    scopus 로고
    • T regulatory cells 1 inhibit a Th2-specific response in vivo
    • Cottrez F., Hurst S.D., Coffman R.L., et al. T regulatory cells 1 inhibit a Th2-specific response in vivo. J Immunol 165 (2000) 4848-4853
    • (2000) J Immunol , vol.165 , pp. 4848-4853
    • Cottrez, F.1    Hurst, S.D.2    Coffman, R.L.3
  • 36
    • 0038363534 scopus 로고    scopus 로고
    • IL-10 and TGF-β cooperate in regulatory T cell response to mucosal allergens in normal immunity and specific immunotherapy
    • Jutel M., Akdis M., Budak F., et al. IL-10 and TGF-β cooperate in regulatory T cell response to mucosal allergens in normal immunity and specific immunotherapy. Eur J Immunol 33 (2003) 1205-1214
    • (2003) Eur J Immunol , vol.33 , pp. 1205-1214
    • Jutel, M.1    Akdis, M.2    Budak, F.3
  • 37
    • 0034119451 scopus 로고    scopus 로고
    • Global initiative for asthma (GINA) and its objectives
    • Bousquet J. Global initiative for asthma (GINA) and its objectives. Clin Exp Allergy 30 Suppl 1 (2000) 2-5
    • (2000) Clin Exp Allergy , vol.30 , Issue.SUPPL. 1 , pp. 2-5
    • Bousquet, J.1
  • 38
    • 0035959904 scopus 로고    scopus 로고
    • Histamine regulates T-cell and antibody responses by differential expression of H1 and H2 receptors
    • Jutel M., Watanabe T., Klunker S., et al. Histamine regulates T-cell and antibody responses by differential expression of H1 and H2 receptors. Nature 413 (2001) 420-425
    • (2001) Nature , vol.413 , pp. 420-425
    • Jutel, M.1    Watanabe, T.2    Klunker, S.3
  • 39
    • 0036205047 scopus 로고    scopus 로고
    • Asthma: more than an inflammatory disease
    • Holgate S.T. Asthma: more than an inflammatory disease. Curr Opin Allergy Clin Immunol 2 (2002) 27-29
    • (2002) Curr Opin Allergy Clin Immunol , vol.2 , pp. 27-29
    • Holgate, S.T.1
  • 40
    • 4344634262 scopus 로고    scopus 로고
    • Advances in immunological treatment of allergy
    • Kussebi F., Karamloo F., Akdis M., et al. Advances in immunological treatment of allergy. Curr Med Chem 2 (2003) 297-308
    • (2003) Curr Med Chem , vol.2 , pp. 297-308
    • Kussebi, F.1    Karamloo, F.2    Akdis, M.3
  • 41
    • 0027296010 scopus 로고
    • Position paper: Immunotherapy with hymenoptera venoms
    • Müller U.R., and Mosbech H. Position paper: Immunotherapy with hymenoptera venoms. Allergy 48 (1993) 36-46
    • (1993) Allergy , vol.48 , pp. 36-46
    • Müller, U.R.1    Mosbech, H.2
  • 42
    • 2442648797 scopus 로고    scopus 로고
    • Allergen immunotherapy: therapeutic vaccines for allergic diseases. World Health Organization. American academy of Allergy, Asthma and Immunology
    • Bousquet J., Lockey R., Malling H.J., et al. Allergen immunotherapy: therapeutic vaccines for allergic diseases. World Health Organization. American academy of Allergy, Asthma and Immunology. Ann Allergy Asthma Immunol 81 (1998) 401-405
    • (1998) Ann Allergy Asthma Immunol , vol.81 , pp. 401-405
    • Bousquet, J.1    Lockey, R.2    Malling, H.J.3
  • 43
    • 0029013533 scopus 로고
    • Grass pollen immunotherapy: efficacy and safety during a 4-year follow- up study
    • Walker S.M., Varney V.A., Gaga M., et al. Grass pollen immunotherapy: efficacy and safety during a 4-year follow- up study. Allergy 50 (1995) 405-413
    • (1995) Allergy , vol.50 , pp. 405-413
    • Walker, S.M.1    Varney, V.A.2    Gaga, M.3
  • 44
    • 0025979907 scopus 로고
    • Usefulness of immunotherapy in patients with severe summer hay fever uncontrolled by antiallergic drugs
    • Varney V.A., Gaga M., Frew A.J., et al. Usefulness of immunotherapy in patients with severe summer hay fever uncontrolled by antiallergic drugs. BMJ 302 (1991) 265-269
    • (1991) BMJ , vol.302 , pp. 265-269
    • Varney, V.A.1    Gaga, M.2    Frew, A.J.3
  • 45
    • 0033549827 scopus 로고    scopus 로고
    • Long-term clinical efficacy of grass-pollen immunotherapy
    • Durham S.R., Walker S.M., Varga E.M., et al. Long-term clinical efficacy of grass-pollen immunotherapy. N Engl J Med 341 (1999) 468-475
    • (1999) N Engl J Med , vol.341 , pp. 468-475
    • Durham, S.R.1    Walker, S.M.2    Varga, E.M.3
  • 46
    • 50249230114 scopus 로고
    • Prophylactic inoculation against hay fever
    • Noon L. Prophylactic inoculation against hay fever. Lancet 1 (1911) 1572-1573
    • (1911) Lancet , vol.1 , pp. 1572-1573
    • Noon, L.1
  • 47
    • 34247569209 scopus 로고
    • Serological evidence of immunity with coexisting sensitization in a type of human allergy (hay fever)
    • Cooke R., Banard J.H., Hebald S., et al. Serological evidence of immunity with coexisting sensitization in a type of human allergy (hay fever). J Exp Med 62 (1935) 733-751
    • (1935) J Exp Med , vol.62 , pp. 733-751
    • Cooke, R.1    Banard, J.H.2    Hebald, S.3
  • 48
    • 0001461109 scopus 로고
    • In vitro studies of human ragweed allergy: changes in cellular and humoral activity associated with specific desensitization
    • Lichtenstein L., Norman P.S., Winkenwerder W.L., et al. In vitro studies of human ragweed allergy: changes in cellular and humoral activity associated with specific desensitization. J Clin Invest 45 (1966) 1126-1136
    • (1966) J Clin Invest , vol.45 , pp. 1126-1136
    • Lichtenstein, L.1    Norman, P.S.2    Winkenwerder, W.L.3
  • 49
    • 0029820287 scopus 로고    scopus 로고
    • Epitope-specific T cell tolerance to phospholipase A2 in bee venom immunotherapy and recovery by IL-2 and IL-15 in vitro
    • Akdis C.A., Akdis M., Blesken T., et al. Epitope-specific T cell tolerance to phospholipase A2 in bee venom immunotherapy and recovery by IL-2 and IL-15 in vitro. J Clin Invest 98 (1996) 1676-1683
    • (1996) J Clin Invest , vol.98 , pp. 1676-1683
    • Akdis, C.A.1    Akdis, M.2    Blesken, T.3
  • 50
    • 0031784380 scopus 로고    scopus 로고
    • Immunological changes associated with allergen immunotherapy
    • Durham S.R., and Till S.J. Immunological changes associated with allergen immunotherapy. J Allergy Clin Immunol 102 (1998) 157-164
    • (1998) J Allergy Clin Immunol , vol.102 , pp. 157-164
    • Durham, S.R.1    Till, S.J.2
  • 51
  • 52
    • 0032921181 scopus 로고    scopus 로고
    • IL-10-induced anergy in peripheral T cell and reactivation by microenvironmental cytokines: two key steps in specific immunotherapy
    • Akdis C.A., and Blaser K. IL-10-induced anergy in peripheral T cell and reactivation by microenvironmental cytokines: two key steps in specific immunotherapy. FASEB J 13 (1999) 603-609
    • (1999) FASEB J , vol.13 , pp. 603-609
    • Akdis, C.A.1    Blaser, K.2
  • 53
    • 0032910288 scopus 로고    scopus 로고
    • Immunological mechanisms operative in allergen-specific immunotherapy
    • Ebner C. Immunological mechanisms operative in allergen-specific immunotherapy. Int Arch Allergy Immunol 119 (1999) 1-5
    • (1999) Int Arch Allergy Immunol , vol.119 , pp. 1-5
    • Ebner, C.1
  • 54
    • 0034110867 scopus 로고    scopus 로고
    • Mechanisms of allergen-specific immunotherapy
    • Akdis C.A., and Blaser K. Mechanisms of allergen-specific immunotherapy. Allergy 55 (2000) 522-530
    • (2000) Allergy , vol.55 , pp. 522-530
    • Akdis, C.A.1    Blaser, K.2
  • 55
    • 0036687715 scopus 로고    scopus 로고
    • Conversion of grass pollen allergen-specific human IgE into a protective IgG(1) antibody
    • Flicker S., Steinberger P., Norderhaug L., et al. Conversion of grass pollen allergen-specific human IgE into a protective IgG(1) antibody. Eur J Immunol 32 (2002) 2156-2162
    • (2002) Eur J Immunol , vol.32 , pp. 2156-2162
    • Flicker, S.1    Steinberger, P.2    Norderhaug, L.3
  • 56
    • 0021881052 scopus 로고
    • Isotypic and idiotypic characterization of anti-bee venom phospholipase A2 antibodies
    • Wetterwald A., Skvaril F., Muller U., et al. Isotypic and idiotypic characterization of anti-bee venom phospholipase A2 antibodies. Int Arch Allergy Appl Immunol 77 (1985) 195-197
    • (1985) Int Arch Allergy Appl Immunol , vol.77 , pp. 195-197
    • Wetterwald, A.1    Skvaril, F.2    Muller, U.3
  • 57
    • 0033197966 scopus 로고    scopus 로고
    • Blocking antibodies induced by specific allergy vaccination prevent the activation of CD4 + T cells by inhibiting serum-IgE-facilitated allergen presentation
    • van Neerven R.J., Wikborg T., Lund G., et al. Blocking antibodies induced by specific allergy vaccination prevent the activation of CD4 + T cells by inhibiting serum-IgE-facilitated allergen presentation. J Immunol 163 (1999) 2944-2952
    • (1999) J Immunol , vol.163 , pp. 2944-2952
    • van Neerven, R.J.1    Wikborg, T.2    Lund, G.3
  • 58
    • 0018875627 scopus 로고
    • Generation of antigen-specific suppressor cells during allergy desensitization
    • Rocklin R.E., Sheffer A., Greineder D.K., et al. Generation of antigen-specific suppressor cells during allergy desensitization. N Engl J Med 302 (1980) 1213-1219
    • (1980) N Engl J Med , vol.302 , pp. 1213-1219
    • Rocklin, R.E.1    Sheffer, A.2    Greineder, D.K.3
  • 59
    • 0022337169 scopus 로고
    • Nasal challenge with ragweed pollen in hay fever patients. Effect of immunotherapy
    • Creticos P.S., Adkinson Jr. N.F., Kagey-Sobotka A., et al. Nasal challenge with ragweed pollen in hay fever patients. Effect of immunotherapy. J Clin Invest 76 (1985) 2247-2253
    • (1985) J Clin Invest , vol.76 , pp. 2247-2253
    • Creticos, P.S.1    Adkinson Jr., N.F.2    Kagey-Sobotka, A.3
  • 60
    • 0023722274 scopus 로고
    • The effect of immunotherapy on bronchial hyperresponsiveness and eosinophil cationic protein in pollen-allergic patients
    • Rak S., Lowhagen O., and Venge P. The effect of immunotherapy on bronchial hyperresponsiveness and eosinophil cationic protein in pollen-allergic patients. J Allergy Clin Immunol 82 (1988) 470-480
    • (1988) J Allergy Clin Immunol , vol.82 , pp. 470-480
    • Rak, S.1    Lowhagen, O.2    Venge, P.3
  • 61
    • 0026093155 scopus 로고
    • Changes in nasal metachromatic cells during allergen immunotherapy
    • Otsuka H., Mezawa A., Ohnishi M., et al. Changes in nasal metachromatic cells during allergen immunotherapy. Clin Exp Allergy 21 (1991) 115-119
    • (1991) Clin Exp Allergy , vol.21 , pp. 115-119
    • Otsuka, H.1    Mezawa, A.2    Ohnishi, M.3
  • 62
    • 0028901793 scopus 로고
    • Bee venom immunotherapy results in decrease of IL-4 and IL-5 and increase of IFN-gamma secretion in specific allergen-stimulated T cell cultures
    • Jutel M., Pichler W.J., Skrbic D., et al. Bee venom immunotherapy results in decrease of IL-4 and IL-5 and increase of IFN-gamma secretion in specific allergen-stimulated T cell cultures. J Immunol 154 (1995) 4187-4194
    • (1995) J Immunol , vol.154 , pp. 4187-4194
    • Jutel, M.1    Pichler, W.J.2    Skrbic, D.3
  • 63
    • 0027443372 scopus 로고
    • Allergen immunotherapy decreases interleukin 4 production in CD4 + T cells from allergic individuals
    • Secrist H., Chelen C.J., Wen Y., et al. Allergen immunotherapy decreases interleukin 4 production in CD4 + T cells from allergic individuals. J Exp Med 178 (1993) 2123-2130
    • (1993) J Exp Med , vol.178 , pp. 2123-2130
    • Secrist, H.1    Chelen, C.J.2    Wen, Y.3
  • 64
    • 0030956363 scopus 로고    scopus 로고
    • Insect venom immunotherapy induces interleukin-10 production and a Th2- to-Th1 shift, and changes surface marker expression in venom-allergic subjects
    • Bellinghausen I., Metz G., Enk A.H., et al. Insect venom immunotherapy induces interleukin-10 production and a Th2- to-Th1 shift, and changes surface marker expression in venom-allergic subjects. Eur J Immunol 27 (1997) 1131-1139
    • (1997) Eur J Immunol , vol.27 , pp. 1131-1139
    • Bellinghausen, I.1    Metz, G.2    Enk, A.H.3
  • 65
    • 0027222095 scopus 로고
    • Influence of grass pollen immunotherapy on cellular infiltration and cytokine mRNA expression during allergen-induced late-phase cutaneous responses
    • Varney V.A., Hamid Q.A., Gaga M., et al. Influence of grass pollen immunotherapy on cellular infiltration and cytokine mRNA expression during allergen-induced late-phase cutaneous responses. J Clin Invest 92 (1993) 644-651
    • (1993) J Clin Invest , vol.92 , pp. 644-651
    • Varney, V.A.1    Hamid, Q.A.2    Gaga, M.3
  • 66
    • 0034283675 scopus 로고    scopus 로고
    • T cells from human allergen-induced late asthmatic responses express IL-12 receptor beta 2 subunit mRNA and respond to IL-12 in vitro
    • Varga E.M., Wachholz P., Nouri-Aria K.T., et al. T cells from human allergen-induced late asthmatic responses express IL-12 receptor beta 2 subunit mRNA and respond to IL-12 in vitro. J Immunol 165 (2000) 2877-2885
    • (2000) J Immunol , vol.165 , pp. 2877-2885
    • Varga, E.M.1    Wachholz, P.2    Nouri-Aria, K.T.3
  • 67
    • 0031041686 scopus 로고    scopus 로고
    • Increases in IL-12 messenger RNA + cells accompany inhibition of allergen-induced late skin responses after successful grass pollen immunotherapy
    • Hamid Q.A., Schotman E., Jacobson M.R., et al. Increases in IL-12 messenger RNA + cells accompany inhibition of allergen-induced late skin responses after successful grass pollen immunotherapy. J Allergy Clin Immunol 99 (1997) 254-260
    • (1997) J Allergy Clin Immunol , vol.99 , pp. 254-260
    • Hamid, Q.A.1    Schotman, E.2    Jacobson, M.R.3
  • 68
    • 0030003889 scopus 로고    scopus 로고
    • Grass pollen immunotherapy inhibits allergen-induced infiltration of CD4 + T lymphocytes and eosinophils in the nasal mucosa and increases the number of cells expressing messenger RNA for interferon-gamma
    • Durham S.R., Ying S., Varney V.A., et al. Grass pollen immunotherapy inhibits allergen-induced infiltration of CD4 + T lymphocytes and eosinophils in the nasal mucosa and increases the number of cells expressing messenger RNA for interferon-gamma. J Allergy Clin Immunol 97 (1996) 1356-1365
    • (1996) J Allergy Clin Immunol , vol.97 , pp. 1356-1365
    • Durham, S.R.1    Ying, S.2    Varney, V.A.3
  • 69
    • 0036164580 scopus 로고    scopus 로고
    • Grass pollen immunotherapy for hayfever is associated with increases in local nasal but not peripheral Th1:Th2 cytokine ratios
    • Wachholz P.A., Nouri-Aria K.T., Wilson D.R., et al. Grass pollen immunotherapy for hayfever is associated with increases in local nasal but not peripheral Th1:Th2 cytokine ratios. Immunology 105 (2002) 56-62
    • (2002) Immunology , vol.105 , pp. 56-62
    • Wachholz, P.A.1    Nouri-Aria, K.T.2    Wilson, D.R.3
  • 70
    • 2942685507 scopus 로고    scopus 로고
    • Immune responses in healthy and allergic individuals are characterized by a fine balance between allergen-specific T regulatory 1 and T helper 2 cells
    • Akdis M., Verhagen J., Taylor A., et al. Immune responses in healthy and allergic individuals are characterized by a fine balance between allergen-specific T regulatory 1 and T helper 2 cells. J Exp Med 199 (2004) 1567-1575
    • (2004) J Exp Med , vol.199 , pp. 1567-1575
    • Akdis, M.1    Verhagen, J.2    Taylor, A.3
  • 71
    • 32944473854 scopus 로고    scopus 로고
    • Regulation of T cells and cytokines by the interleukin-10 (IL-10)-family cytokines IL-19, IL-20, IL-22, IL-24 andIL-26
    • Oral H.B., Kotenko S.V., Yilmaz M., et al. Regulation of T cells and cytokines by the interleukin-10 (IL-10)-family cytokines IL-19, IL-20, IL-22, IL-24 andIL-26. Eur J Immunol 36 (2006) 380-388
    • (2006) Eur J Immunol , vol.36 , pp. 380-388
    • Oral, H.B.1    Kotenko, S.V.2    Yilmaz, M.3
  • 72
    • 0029984767 scopus 로고    scopus 로고
    • Interleukin-10 regulation in normal subjects and patients with asthma
    • Borish L., Aarons A., Rumbyrt J., et al. Interleukin-10 regulation in normal subjects and patients with asthma. J Allergy Clin Immunol 97 (1996) 1288-1296
    • (1996) J Allergy Clin Immunol , vol.97 , pp. 1288-1296
    • Borish, L.1    Aarons, A.2    Rumbyrt, J.3
  • 73
    • 0031150153 scopus 로고    scopus 로고
    • T cells subsets and cytokines in allergic and non-allergic children. II. Analysis and IL-5 and IL-10 mRNA expression and protein production
    • Koning H., Neijens H.J., Baert M.R., et al. T cells subsets and cytokines in allergic and non-allergic children. II. Analysis and IL-5 and IL-10 mRNA expression and protein production. Cytokine 9 (1997) 427-436
    • (1997) Cytokine , vol.9 , pp. 427-436
    • Koning, H.1    Neijens, H.J.2    Baert, M.R.3
  • 74
    • 8544230635 scopus 로고    scopus 로고
    • Transforming growth factor-beta expression in mucosal biopsies in asthma and chronic bronchitis
    • Vignola A.M., Chanez P., Chiappara G., et al. Transforming growth factor-beta expression in mucosal biopsies in asthma and chronic bronchitis. Am J Respir Crit Care Med 156 (1997) 591-599
    • (1997) Am J Respir Crit Care Med , vol.156 , pp. 591-599
    • Vignola, A.M.1    Chanez, P.2    Chiappara, G.3
  • 75
    • 0036177295 scopus 로고    scopus 로고
    • Blockade of CTLA-4 enhances allergic sensitization and eosinophilic airway inflammation in genetically predisposed mice
    • Hellings P.W., Vandenberghe P., Kasran A., et al. Blockade of CTLA-4 enhances allergic sensitization and eosinophilic airway inflammation in genetically predisposed mice. Eur J Immunol 32 (2002) 585-594
    • (2002) Eur J Immunol , vol.32 , pp. 585-594
    • Hellings, P.W.1    Vandenberghe, P.2    Kasran, A.3
  • 76
    • 0027171964 scopus 로고
    • IL-10 and viral IL-10 prevent IL-4-indiced IgE synthesis by inhibiting the accessory cell function of monocytes
    • Punnonen J., De Waal Malefyt R., Van Vlasselaer P., et al. IL-10 and viral IL-10 prevent IL-4-indiced IgE synthesis by inhibiting the accessory cell function of monocytes. J Immunol 151 (1993) 1280-1289
    • (1993) J Immunol , vol.151 , pp. 1280-1289
    • Punnonen, J.1    De Waal Malefyt, R.2    Van Vlasselaer, P.3
  • 77
    • 0024445451 scopus 로고
    • Transforming growth factor beta induces IgA production and acts additively with interleukin 5 for IgA production
    • Sonoda E., Matsumoto R., Hitoshi Y., et al. Transforming growth factor beta induces IgA production and acts additively with interleukin 5 for IgA production. J Exp Med 170 (1989) 1415-1420
    • (1989) J Exp Med , vol.170 , pp. 1415-1420
    • Sonoda, E.1    Matsumoto, R.2    Hitoshi, Y.3
  • 78
    • 0141958643 scopus 로고    scopus 로고
    • Renaissance of the blocking antibody concept in type I allergy
    • Flicker S., and Valenta R. Renaissance of the blocking antibody concept in type I allergy. Int Arch Allergy Immunol 132 (2003) 13-24
    • (2003) Int Arch Allergy Immunol , vol.132 , pp. 13-24
    • Flicker, S.1    Valenta, R.2
  • 80
    • 0019976840 scopus 로고
    • Clinical relevance of the venom-specific immunoglobulin G antibody level during immunotherapy
    • Golden D.B., Meyers D.A., Kagey-Sobotka A., et al. Clinical relevance of the venom-specific immunoglobulin G antibody level during immunotherapy. J Allergy Clin Immunol 69 (1982) 489-493
    • (1982) J Allergy Clin Immunol , vol.69 , pp. 489-493
    • Golden, D.B.1    Meyers, D.A.2    Kagey-Sobotka, A.3
  • 81
    • 0024324363 scopus 로고
    • Predictive value of venom-specific IgE, IgG and IgG subclass antibodies in patients on immunotherapy with honey bee venom
    • Müller U.R., Helbling A., and Bischof M. Predictive value of venom-specific IgE, IgG and IgG subclass antibodies in patients on immunotherapy with honey bee venom. Allergy 44 (1989) 412-418
    • (1989) Allergy , vol.44 , pp. 412-418
    • Müller, U.R.1    Helbling, A.2    Bischof, M.3
  • 82
    • 10744232817 scopus 로고    scopus 로고
    • Grass pollen immunotherapy induces mucosal and peripheral IL-10 responses and blocking IgG activity
    • Nouri-Aria K.T., Wachholz P.A., Francis J.N., et al. Grass pollen immunotherapy induces mucosal and peripheral IL-10 responses and blocking IgG activity. J Immunol 172 (2004) 3252-3259
    • (2004) J Immunol , vol.172 , pp. 3252-3259
    • Nouri-Aria, K.T.1    Wachholz, P.A.2    Francis, J.N.3
  • 83
    • 24644509434 scopus 로고    scopus 로고
    • Allergen-specific immunotherapy with recombinant grass pollen allergens
    • Jutel M., Jaeger L., Suck R., et al. Allergen-specific immunotherapy with recombinant grass pollen allergens. J Allergy Clin Immunol 116 (2005) 608-613
    • (2005) J Allergy Clin Immunol , vol.116 , pp. 608-613
    • Jutel, M.1    Jaeger, L.2    Suck, R.3
  • 84
    • 4644326199 scopus 로고    scopus 로고
    • Evaluation of recombinant and native timothy pollen (rPhl p 1, 2, 5, 6, 7, 11, 12 and nPhl p 4)- specific IgG4 antibodies induced by subcutaneous immunotherapy with timothy pollen extract in allergic patients
    • Rossi R.E., and Monasterolo G. Evaluation of recombinant and native timothy pollen (rPhl p 1, 2, 5, 6, 7, 11, 12 and nPhl p 4)- specific IgG4 antibodies induced by subcutaneous immunotherapy with timothy pollen extract in allergic patients. Int Arch Allergy Immunol 135 (2004) 44-53
    • (2004) Int Arch Allergy Immunol , vol.135 , pp. 44-53
    • Rossi, R.E.1    Monasterolo, G.2
  • 85
    • 0025805857 scopus 로고
    • T cell subsets and their soluble products regulate eosinophilia in allergic and nonallergic asthma
    • Walker C., Virchow J.-C., Bruijnzeel P.L.B., et al. T cell subsets and their soluble products regulate eosinophilia in allergic and nonallergic asthma. J Immunol 146 (1991) 1829-1835
    • (1991) J Immunol , vol.146 , pp. 1829-1835
    • Walker, C.1    Virchow, J.-C.2    Bruijnzeel, P.L.B.3
  • 86
    • 0024323445 scopus 로고
    • Regulation of human basophil mediator release by cytokines. I. Interaction with anti-inflammatory steroids
    • Schleimer R.P., Derse C.P., Friedman B., et al. Regulation of human basophil mediator release by cytokines. I. Interaction with anti-inflammatory steroids. J Immunol 143 (1989) 1310-1327
    • (1989) J Immunol , vol.143 , pp. 1310-1327
    • Schleimer, R.P.1    Derse, C.P.2    Friedman, B.3
  • 87
    • 0030025471 scopus 로고    scopus 로고
    • Interleukin (IL)-10 Inhibits long-term IL-6 production but not preformed mediator release from rat peritoneal mast cells
    • Marshall J.S., Leal-Berumen I., Nielsen L., et al. Interleukin (IL)-10 Inhibits long-term IL-6 production but not preformed mediator release from rat peritoneal mast cells. J Clin Invest 97 (1996) 1122-1128
    • (1996) J Clin Invest , vol.97 , pp. 1122-1128
    • Marshall, J.S.1    Leal-Berumen, I.2    Nielsen, L.3
  • 88
    • 0028181890 scopus 로고
    • B7/CD28-dependent IL-5 production by human resting T cells is inhibited by IL-10
    • Schandane L., Alonso-Vega C., Willems F., et al. B7/CD28-dependent IL-5 production by human resting T cells is inhibited by IL-10. J Immunol 152 (1994) 4368-4374
    • (1994) J Immunol , vol.152 , pp. 4368-4374
    • Schandane, L.1    Alonso-Vega, C.2    Willems, F.3
  • 89
    • 0030008077 scopus 로고    scopus 로고
    • CD40 expression by human peripheral blood eosinophils
    • Ohkawara Y., Lim K.G., Glibetic M., et al. CD40 expression by human peripheral blood eosinophils. J Clin Invest 97 (1996) 1761-1766
    • (1996) J Clin Invest , vol.97 , pp. 1761-1766
    • Ohkawara, Y.1    Lim, K.G.2    Glibetic, M.3
  • 90
    • 0035672339 scopus 로고    scopus 로고
    • Tolerance and near-tolerance strategies in monkeys and their application to human renal transplantation
    • Knechtle S.J., Hamawy M.M., Hu H., et al. Tolerance and near-tolerance strategies in monkeys and their application to human renal transplantation. Immunol Rev 183 (2001) 205-213
    • (2001) Immunol Rev , vol.183 , pp. 205-213
    • Knechtle, S.J.1    Hamawy, M.M.2    Hu, H.3
  • 91
    • 0034921235 scopus 로고    scopus 로고
    • The expanding world of co-stimulation: the two-signal model revisited
    • Chambers C.A. The expanding world of co-stimulation: the two-signal model revisited. Trends Immunol 22 (2001) 217-223
    • (2001) Trends Immunol , vol.22 , pp. 217-223
    • Chambers, C.A.1
  • 92
    • 0030056468 scopus 로고    scopus 로고
    • Models of T cell anergy: is there a common molecular mechanism?
    • Schwartz R.H. Models of T cell anergy: is there a common molecular mechanism?. J Exp Med 184 (1996) 1-8
    • (1996) J Exp Med , vol.184 , pp. 1-8
    • Schwartz, R.H.1
  • 93
  • 94
    • 0027451437 scopus 로고
    • Inhibition of T cell and antibody responses to house dust mite allergen by inhalation of the dominant T cell epitope in naive and sensitized mice
    • Hoyne G.F., O'Hehir R., Wraith D.C., et al. Inhibition of T cell and antibody responses to house dust mite allergen by inhalation of the dominant T cell epitope in naive and sensitized mice. J Exp Med 178 (1993) 1783-1788
    • (1993) J Exp Med , vol.178 , pp. 1783-1788
    • Hoyne, G.F.1    O'Hehir, R.2    Wraith, D.C.3
  • 95
    • 0032914146 scopus 로고    scopus 로고
    • Anti-CD86 (B7.2) treatment abolishes allergic airway hyperresponsiveness in mice
    • Haczku A., Takeda K., Redai I., et al. Anti-CD86 (B7.2) treatment abolishes allergic airway hyperresponsiveness in mice. Am J Respir Crit Care Med 159 (1999) 1638-1643
    • (1999) Am J Respir Crit Care Med , vol.159 , pp. 1638-1643
    • Haczku, A.1    Takeda, K.2    Redai, I.3
  • 96
    • 0031228810 scopus 로고    scopus 로고
    • Murine CTLA4-IgG treatment inhibits airway eosinophilia and hyperresponsiveness and attenuates IgE upregulation in a murine model of allergic asthma
    • Van Oosterhout A.J., Hofstra C.L., Shields R., et al. Murine CTLA4-IgG treatment inhibits airway eosinophilia and hyperresponsiveness and attenuates IgE upregulation in a murine model of allergic asthma. Am J Respir Cell Mol Biol 17 (1997) 386-392
    • (1997) Am J Respir Cell Mol Biol , vol.17 , pp. 386-392
    • Van Oosterhout, A.J.1    Hofstra, C.L.2    Shields, R.3
  • 97
    • 0031867521 scopus 로고    scopus 로고
    • Requirement of CD28-CD86 costimulation for allergen-specific T cell proliferation and cytokine expression
    • Van Neerven R.J., Van de Pol M.M., Van der Zee J.S., et al. Requirement of CD28-CD86 costimulation for allergen-specific T cell proliferation and cytokine expression. Clin Exp Allergy 28 (1998) 808-816
    • (1998) Clin Exp Allergy , vol.28 , pp. 808-816
    • Van Neerven, R.J.1    Van de Pol, M.M.2    Van der Zee, J.S.3
  • 98
    • 0034912364 scopus 로고    scopus 로고
    • ICOS is critical for T helper cell-mediated lung mucosal inflammatory responses
    • Gonzalo J.A., Tian J., Delaney T., et al. ICOS is critical for T helper cell-mediated lung mucosal inflammatory responses. Nat Immunol 2 (2001) 597-604
    • (2001) Nat Immunol , vol.2 , pp. 597-604
    • Gonzalo, J.A.1    Tian, J.2    Delaney, T.3
  • 99
    • 0035804254 scopus 로고    scopus 로고
    • ICOS co-stimulatory receptor is essential for T-cell activation and function
    • Dong C., Juedes A.E., Temann U.A., et al. ICOS co-stimulatory receptor is essential for T-cell activation and function. Nature 409 (2001) 97-101
    • (2001) Nature , vol.409 , pp. 97-101
    • Dong, C.1    Juedes, A.E.2    Temann, U.A.3
  • 100
    • 0033813696 scopus 로고    scopus 로고
    • A molecular basis for T cell suppression by IL-10: CD28-associated IL-10 receptor inhibits CD28 tyrosine phosphorylation and phosphatidylinositol 3-kinase binding
    • Akdis C.A., Joss A., Akdis M., et al. A molecular basis for T cell suppression by IL-10: CD28-associated IL-10 receptor inhibits CD28 tyrosine phosphorylation and phosphatidylinositol 3-kinase binding. FASEB J 14 (2000) 1666-1669
    • (2000) FASEB J , vol.14 , pp. 1666-1669
    • Akdis, C.A.1    Joss, A.2    Akdis, M.3
  • 101
    • 0034039840 scopus 로고    scopus 로고
    • IL-10 directly acts on T cells by specifically altering the CD28 co-stimulation pathway
    • Joss A., Akdis M., Faith A., et al. IL-10 directly acts on T cells by specifically altering the CD28 co-stimulation pathway. Eur J Immunol 30 (2000) 1683-1690
    • (2000) Eur J Immunol , vol.30 , pp. 1683-1690
    • Joss, A.1    Akdis, M.2    Faith, A.3
  • 102
    • 0028221022 scopus 로고
    • T-cell antigen CD28 interacts with the lipid kinase phosphatidylinositol 3-kinase by a cytoplasmic Tyr(P)-Met-Xaa-Met motif
    • Prasad K.V.S., Cai Y.-C., Raab M., et al. T-cell antigen CD28 interacts with the lipid kinase phosphatidylinositol 3-kinase by a cytoplasmic Tyr(P)-Met-Xaa-Met motif. Proc Natl Acad Sci USA 91 (1994) 2834-2838
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 2834-2838
    • Prasad, K.V.S.1    Cai, Y.-C.2    Raab, M.3
  • 103
    • 0035339884 scopus 로고    scopus 로고
    • IFN-alpha and IL-10 induce the differentiation of human type 1 T regulatory cells
    • Levings M.K., Sangregorio R., Galbiati F., et al. IFN-alpha and IL-10 induce the differentiation of human type 1 T regulatory cells. J Immunol 166 (2001) 5530-5539
    • (2001) J Immunol , vol.166 , pp. 5530-5539
    • Levings, M.K.1    Sangregorio, R.2    Galbiati, F.3
  • 104
    • 0036687184 scopus 로고    scopus 로고
    • Growth and expansion of human T regulatory type 1 cells are independent from TCR activation but require exogenous cytokines
    • Bacchetta R., Sartirana C., Levings M.K., et al. Growth and expansion of human T regulatory type 1 cells are independent from TCR activation but require exogenous cytokines. Eur J Immunol 32 (2002) 2237-2245
    • (2002) Eur J Immunol , vol.32 , pp. 2237-2245
    • Bacchetta, R.1    Sartirana, C.2    Levings, M.K.3
  • 107
    • 0037018104 scopus 로고    scopus 로고
    • In vitro generation of interleukin 10-producing regulatory CD4(+) T cells is induced by immunosuppressive drugs and inhibited by T helper type 1 (Th1)- and Th2-inducing cytokines
    • Barrat F.J., Cua D.J., Boonstra A., et al. In vitro generation of interleukin 10-producing regulatory CD4(+) T cells is induced by immunosuppressive drugs and inhibited by T helper type 1 (Th1)- and Th2-inducing cytokines. J Exp Med 195 (2002) 603-616
    • (2002) J Exp Med , vol.195 , pp. 603-616
    • Barrat, F.J.1    Cua, D.J.2    Boonstra, A.3
  • 108
    • 0035666653 scopus 로고    scopus 로고
    • Interleukin-10 levels increase in cutaneous biopsies of patients undergoing wasp venom immunotherapy
    • Nasser S.M., Ying S., Meng O., et al. Interleukin-10 levels increase in cutaneous biopsies of patients undergoing wasp venom immunotherapy. Eur J Immunol 31 (2001) 3704-3713
    • (2001) Eur J Immunol , vol.31 , pp. 3704-3713
    • Nasser, S.M.1    Ying, S.2    Meng, O.3
  • 109
    • 0030043855 scopus 로고    scopus 로고
    • Oral tolerance in myelin basic protein T-cell receptor transgenic mice: suppression of autoimmune encephalomyelitis and dose-dependent induction of regulatory cells
    • Chen Y., Inobe J., Kuchroo V.K., et al. Oral tolerance in myelin basic protein T-cell receptor transgenic mice: suppression of autoimmune encephalomyelitis and dose-dependent induction of regulatory cells. Proc Natl Acad Sci USA 93 (1996) 388-391
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 388-391
    • Chen, Y.1    Inobe, J.2    Kuchroo, V.K.3
  • 110
    • 0029150110 scopus 로고
    • Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases
    • Sakaguchi S., Sakaguchi N., Asano M., et al. Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases. J Immunol 155 (1995) 1151-1164
    • (1995) J Immunol , vol.155 , pp. 1151-1164
    • Sakaguchi, S.1    Sakaguchi, N.2    Asano, M.3
  • 111
    • 0036597371 scopus 로고    scopus 로고
    • CD4 + CD25 + suppressor T cells: more questions than answers
    • Shevach E.M. CD4 + CD25 + suppressor T cells: more questions than answers. Nat Rev Immunol 2 (2002) 389-400
    • (2002) Nat Rev Immunol , vol.2 , pp. 389-400
    • Shevach, E.M.1
  • 112
    • 0037364976 scopus 로고    scopus 로고
    • Regulatory T cells in transplantation tolerance
    • Wood K.J., and Sakaguchi S. Regulatory T cells in transplantation tolerance. Nat Rev Immunol 3 (2003) 199-210
    • (2003) Nat Rev Immunol , vol.3 , pp. 199-210
    • Wood, K.J.1    Sakaguchi, S.2
  • 113
    • 0035546070 scopus 로고    scopus 로고
    • CD4(+) regulatory T cells
    • Read S., and Powrie F. CD4(+) regulatory T cells. Curr Opin Immunol 13 (2001) 644-649
    • (2001) Curr Opin Immunol , vol.13 , pp. 644-649
    • Read, S.1    Powrie, F.2
  • 114
    • 0347785480 scopus 로고    scopus 로고
    • Control of regulatory T cell development by the transcription factor Foxp3
    • Hori S., Nomura T., and Sakaguchi S. Control of regulatory T cell development by the transcription factor Foxp3. Science 299 (2003) 1057-1061
    • (2003) Science , vol.299 , pp. 1057-1061
    • Hori, S.1    Nomura, T.2    Sakaguchi, S.3
  • 115
    • 0031739410 scopus 로고    scopus 로고
    • CD38 + CD45RB(low) CD4 + T cells: a population of T cells with immune regulatory activities in vitro
    • Read S., Mauze S., Asseman C., et al. CD38 + CD45RB(low) CD4 + T cells: a population of T cells with immune regulatory activities in vitro. Eur J Immunol 28 (1998) 3435-3447
    • (1998) Eur J Immunol , vol.28 , pp. 3435-3447
    • Read, S.1    Mauze, S.2    Asseman, C.3
  • 116
    • 0030060229 scopus 로고    scopus 로고
    • Oral antigen inhibits priming of CD8 + CTL, CD4 + T cells, and antibody responses while activating CD8 + suppressor T cells
    • Ke Y., and Kapp J.A. Oral antigen inhibits priming of CD8 + CTL, CD4 + T cells, and antibody responses while activating CD8 + suppressor T cells. J Immunol 156 (1996) 916-921
    • (1996) J Immunol , vol.156 , pp. 916-921
    • Ke, Y.1    Kapp, J.A.2
  • 117
    • 0031055406 scopus 로고    scopus 로고
    • Oral tolerance for the treatment of autoimmune diseases
    • Weiner H.L. Oral tolerance for the treatment of autoimmune diseases. Annu Rev Med 48 (1997) 341-351
    • (1997) Annu Rev Med , vol.48 , pp. 341-351
    • Weiner, H.L.1
  • 118
    • 0032533472 scopus 로고    scopus 로고
    • Specific suppression of human CD4 + Th cell responses to pig MHC antigens by CD8 + CD28- regulatory T cells
    • Ciubotariu R., Colovai A.I., Pennesi G., et al. Specific suppression of human CD4 + Th cell responses to pig MHC antigens by CD8 + CD28- regulatory T cells. J Immunol 161 (1998) 5193-5202
    • (1998) J Immunol , vol.161 , pp. 5193-5202
    • Ciubotariu, R.1    Colovai, A.I.2    Pennesi, G.3
  • 119
    • 0141449974 scopus 로고    scopus 로고
    • CD4 + CD25 + T cells regulate virus-specific primary and memory CD8 + T cell responses
    • Suvas S., Kumaraguru U., Pack C.D., et al. CD4 + CD25 + T cells regulate virus-specific primary and memory CD8 + T cell responses. J Exp Med 198 (2003) 889-901
    • (2003) J Exp Med , vol.198 , pp. 889-901
    • Suvas, S.1    Kumaraguru, U.2    Pack, C.D.3
  • 120
    • 0029659058 scopus 로고    scopus 로고
    • Double negative (CD4-CD8- alpha beta +) T cells which promote tolerance induction and regulate autoimmunity
    • Strober S., Cheng L., Zeng D., et al. Double negative (CD4-CD8- alpha beta +) T cells which promote tolerance induction and regulate autoimmunity. Immunol Rev 149 (1996) 217-230
    • (1996) Immunol Rev , vol.149 , pp. 217-230
    • Strober, S.1    Cheng, L.2    Zeng, D.3
  • 121
    • 0033929005 scopus 로고    scopus 로고
    • Identification of a previously unknown antigen-specific regulatory T cell and its mechanism of suppression
    • Zhang Z.X., Yang L., Young K.J., et al. Identification of a previously unknown antigen-specific regulatory T cell and its mechanism of suppression. Nat Med 6 (2000) 782-789
    • (2000) Nat Med , vol.6 , pp. 782-789
    • Zhang, Z.X.1    Yang, L.2    Young, K.J.3
  • 122
    • 0033981213 scopus 로고    scopus 로고
    • Gamma delta T cells as mediators of mucosal tolerance: the autoimmune diabetes model
    • Hanninen A., and Harrison L.C. Gamma delta T cells as mediators of mucosal tolerance: the autoimmune diabetes model. Immunol Rev 173 (2000) 109-119
    • (2000) Immunol Rev , vol.173 , pp. 109-119
    • Hanninen, A.1    Harrison, L.C.2
  • 123
    • 0033168162 scopus 로고    scopus 로고
    • Depletion of IL-10- and TGF-beta-producing regulatory gamma delta T cells by administering a daunomycin-conjugated specific monoclonal antibody in early tumor lesions augments the activity of CTLs and NK cells
    • Seo N., Tokura Y., Takigawa M., et al. Depletion of IL-10- and TGF-beta-producing regulatory gamma delta T cells by administering a daunomycin-conjugated specific monoclonal antibody in early tumor lesions augments the activity of CTLs and NK cells. J Immunol 163 (1999) 242-249
    • (1999) J Immunol , vol.163 , pp. 242-249
    • Seo, N.1    Tokura, Y.2    Takigawa, M.3
  • 124
    • 0031569452 scopus 로고    scopus 로고
    • Gamma delta T lymphocytes regulate the induction and maintenance of oral tolerance
    • Ke Y., Pearce K., Lake J.P., et al. Gamma delta T lymphocytes regulate the induction and maintenance of oral tolerance. J Immunol 158 (1997) 3610-3618
    • (1997) J Immunol , vol.158 , pp. 3610-3618
    • Ke, Y.1    Pearce, K.2    Lake, J.P.3
  • 125
    • 0032473551 scopus 로고    scopus 로고
    • Aerosol-induced immunoglobulin (Ig)-E unresponsiveness to ovalbumin does not require CD8 + or T cell receptor (TCR)-gamma/delta + T cells or interferon (IFN)-gamma in a murine model of allergen sensitization
    • Seymour B.W., Gershwin L.J., and Coffman R.L. Aerosol-induced immunoglobulin (Ig)-E unresponsiveness to ovalbumin does not require CD8 + or T cell receptor (TCR)-gamma/delta + T cells or interferon (IFN)-gamma in a murine model of allergen sensitization. J Exp Med 187 (1998) 721-731
    • (1998) J Exp Med , vol.187 , pp. 721-731
    • Seymour, B.W.1    Gershwin, L.J.2    Coffman, R.L.3
  • 126
    • 0037450740 scopus 로고    scopus 로고
    • Prevention of arthritis by interleukin 10-producing B cells
    • Mauri C., Gray D., Mushtaq N., et al. Prevention of arthritis by interleukin 10-producing B cells. J Exp Med 197 (2003) 489-501
    • (2003) J Exp Med , vol.197 , pp. 489-501
    • Mauri, C.1    Gray, D.2    Mushtaq, N.3
  • 127
    • 0034890907 scopus 로고    scopus 로고
    • Pulmonary dendritic cells producing IL-10 mediate tolerance induced by respiratory exposure to antigen
    • Akbari O., DeKruyff R.H., and Umetsu D.T. Pulmonary dendritic cells producing IL-10 mediate tolerance induced by respiratory exposure to antigen. Nat Immunol 2 (2001) 725-731
    • (2001) Nat Immunol , vol.2 , pp. 725-731
    • Akbari, O.1    DeKruyff, R.H.2    Umetsu, D.T.3
  • 128
    • 0031573204 scopus 로고    scopus 로고
    • Induction of tolerance by IL-10-treated dendritic cells
    • Steinbrink K., Wolfl M., Jonuleit H., et al. Induction of tolerance by IL-10-treated dendritic cells. J Immunol 159 (1997) 4772-4780
    • (1997) J Immunol , vol.159 , pp. 4772-4780
    • Steinbrink, K.1    Wolfl, M.2    Jonuleit, H.3
  • 129
    • 0026633935 scopus 로고
    • Autocrine and paracrine regulation of astrocyte function by transforming growth factor-beta
    • Morganti-Kossmann M.C., Kossmann T., Brandes M.E., et al. Autocrine and paracrine regulation of astrocyte function by transforming growth factor-beta. J Neuroimmunol 39 (1992) 163-173
    • (1992) J Neuroimmunol , vol.39 , pp. 163-173
    • Morganti-Kossmann, M.C.1    Kossmann, T.2    Brandes, M.E.3
  • 130
    • 0037379315 scopus 로고    scopus 로고
    • Tumor-derived TGF-beta reduces the efficacy of dendritic cell/tumor fusion vaccine
    • Kao J.Y., Gong Y., Chen C.M., et al. Tumor-derived TGF-beta reduces the efficacy of dendritic cell/tumor fusion vaccine. J Immunol 170 (2003) 3806-3811
    • (2003) J Immunol , vol.170 , pp. 3806-3811
    • Kao, J.Y.1    Gong, Y.2    Chen, C.M.3
  • 131
    • 0027056242 scopus 로고
    • Systemic suppression of delayed-type hypersensitivity by supernatants from UV-irradiated keratinocytes. An essential role for keratinocyte-derived IL-10
    • Rivas J.M., and Ullrich S.E. Systemic suppression of delayed-type hypersensitivity by supernatants from UV-irradiated keratinocytes. An essential role for keratinocyte-derived IL-10. J Immunol 149 (1992) 3865-3871
    • (1992) J Immunol , vol.149 , pp. 3865-3871
    • Rivas, J.M.1    Ullrich, S.E.2
  • 132
    • 0345392603 scopus 로고    scopus 로고
    • Cytokine secretion patterns of NK cells and macrophages in early human pregnancy decidua and blood: implications for suppressor macrophages in decidua
    • Lidstrom C., Matthiesen L., Berg G., et al. Cytokine secretion patterns of NK cells and macrophages in early human pregnancy decidua and blood: implications for suppressor macrophages in decidua. Am J Reprod Immunol 50 (2003) 444-452
    • (2003) Am J Reprod Immunol , vol.50 , pp. 444-452
    • Lidstrom, C.1    Matthiesen, L.2    Berg, G.3
  • 133
    • 0038205944 scopus 로고    scopus 로고
    • NK cells regulate CD4 responses prior to antigen encounter
    • Dowdell K.C., Cua D.J., Kirtkman E., et al. NK cells regulate CD4 responses prior to antigen encounter. J Immunol 171 (2003) 234-239
    • (2003) J Immunol , vol.171 , pp. 234-239
    • Dowdell, K.C.1    Cua, D.J.2    Kirtkman, E.3
  • 134
    • 0030584697 scopus 로고    scopus 로고
    • Transforming growth factor-beta 1 is the predominant paracrine inhibitor of macrophage cytokine synthesis produced by glomerular mesangial cells
    • Kitamura M., Suto T., Yokoo T., et al. Transforming growth factor-beta 1 is the predominant paracrine inhibitor of macrophage cytokine synthesis produced by glomerular mesangial cells. J Immunol 156 (1996) 2964-2971
    • (1996) J Immunol , vol.156 , pp. 2964-2971
    • Kitamura, M.1    Suto, T.2    Yokoo, T.3
  • 135
    • 0035186416 scopus 로고    scopus 로고
    • Induction and mechanism of action of transforming growth factor-beta- secreting Th3 regulatory cells
    • Weiner H.L. Induction and mechanism of action of transforming growth factor-beta- secreting Th3 regulatory cells. Immunol Rev 182 (2001) 207-214
    • (2001) Immunol Rev , vol.182 , pp. 207-214
    • Weiner, H.L.1
  • 136
    • 0033988289 scopus 로고    scopus 로고
    • Anergy and suppression regulate CD4(+) T cell responses to a self peptide
    • Jordan M.S., Riley M.P., von Boehmer H., et al. Anergy and suppression regulate CD4(+) T cell responses to a self peptide. Eur J Immunol 30 (2000) 136-144
    • (2000) Eur J Immunol , vol.30 , pp. 136-144
    • Jordan, M.S.1    Riley, M.P.2    von Boehmer, H.3
  • 137
    • 0035177431 scopus 로고    scopus 로고
    • Specific migratory dendritic cells rapidly transport antigen from the airways to the thoracic lymph nodes
    • Vermaelen K.Y., Carro-Muino I., Lambrecht B.N., et al. Specific migratory dendritic cells rapidly transport antigen from the airways to the thoracic lymph nodes. J Exp Med 193 (2001) 51-60
    • (2001) J Exp Med , vol.193 , pp. 51-60
    • Vermaelen, K.Y.1    Carro-Muino, I.2    Lambrecht, B.N.3
  • 138
    • 0034654008 scopus 로고    scopus 로고
    • Induction of rapid T cell activation, division, and recirculation by intratracheal injection of dendritic cells in a TCR transgenic model
    • Lambrecht B.N., Pauwels R.A., and Fazekas De St Groth B. Induction of rapid T cell activation, division, and recirculation by intratracheal injection of dendritic cells in a TCR transgenic model. J Immunol 164 (2000) 2937-2946
    • (2000) J Immunol , vol.164 , pp. 2937-2946
    • Lambrecht, B.N.1    Pauwels, R.A.2    Fazekas De St Groth, B.3
  • 139
    • 3142720367 scopus 로고    scopus 로고
    • Essential role of lung plasmacytoid dendritic cells in preventing asthmatic reactions to harmless inhaled antigen
    • de Heer H.J., Hammad H., Soullie T., et al. Essential role of lung plasmacytoid dendritic cells in preventing asthmatic reactions to harmless inhaled antigen. J Exp Med 200 (2004) 89-98
    • (2004) J Exp Med , vol.200 , pp. 89-98
    • de Heer, H.J.1    Hammad, H.2    Soullie, T.3
  • 140
    • 21844445109 scopus 로고    scopus 로고
    • Interleukin-10-secreting "regulatory" T cells induced by glucocorticoids and beta2-agonists
    • Peek E.J., Richards D.F., Faith A., et al. Interleukin-10-secreting "regulatory" T cells induced by glucocorticoids and beta2-agonists. Am J Respir Cell Mol Biol 33 (2005) 105-111
    • (2005) Am J Respir Cell Mol Biol , vol.33 , pp. 105-111
    • Peek, E.J.1    Richards, D.F.2    Faith, A.3
  • 141
    • 20844432359 scopus 로고    scopus 로고
    • Glucocorticoids upregulate FOXP3 expression and regulatory T cells in asthma
    • Karagiannidis C., Akdis M., Holopainen P., et al. Glucocorticoids upregulate FOXP3 expression and regulatory T cells in asthma. J Allergy Clin Immunol 114 (2004) 1425-1433
    • (2004) J Allergy Clin Immunol , vol.114 , pp. 1425-1433
    • Karagiannidis, C.1    Akdis, M.2    Holopainen, P.3
  • 142
    • 0027479685 scopus 로고
    • "Infectious" transplantation tolerance
    • Qin S., Cobbold S.P., Pope H., et al. "Infectious" transplantation tolerance. Science 259 (1993) 974-977
    • (1993) Science , vol.259 , pp. 974-977
    • Qin, S.1    Cobbold, S.P.2    Pope, H.3
  • 143
    • 29544440569 scopus 로고    scopus 로고
    • Absence of T-regulatory cell expression and function in atopic dermatitis skin
    • Verhagen J., Akdis M., Traidl-Hoffmann C., et al. Absence of T-regulatory cell expression and function in atopic dermatitis skin. J Allergy Clin Immunol 117 (2006) 176-183
    • (2006) J Allergy Clin Immunol , vol.117 , pp. 176-183
    • Verhagen, J.1    Akdis, M.2    Traidl-Hoffmann, C.3
  • 144
    • 0031821875 scopus 로고    scopus 로고
    • CD4 + CD25 + immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production
    • Thornton A.M., and Shevach E.M. CD4 + CD25 + immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production. J Exp Med 188 (1998) 287-296
    • (1998) J Exp Med , vol.188 , pp. 287-296
    • Thornton, A.M.1    Shevach, E.M.2
  • 145
    • 0035801335 scopus 로고    scopus 로고
    • Cell contact-dependent immunosuppression by CD4(+)CD25(+) regulatory T cells is mediated by cell surface-bound transforming growth factor beta
    • Nakamura K., Kitani A., and Strober W. Cell contact-dependent immunosuppression by CD4(+)CD25(+) regulatory T cells is mediated by cell surface-bound transforming growth factor beta. J Exp Med 194 (2001) 629-644
    • (2001) J Exp Med , vol.194 , pp. 629-644
    • Nakamura, K.1    Kitani, A.2    Strober, W.3
  • 146
    • 0036886390 scopus 로고    scopus 로고
    • The role of IL-10 and TGF-beta in the differentiation and effector function of T regulatory cells
    • Levings M.K., Bachetta R., Schulz U., et al. The role of IL-10 and TGF-beta in the differentiation and effector function of T regulatory cells. Int Arch Allergy Appl Immunol 129 (2002) 263-276
    • (2002) Int Arch Allergy Appl Immunol , vol.129 , pp. 263-276
    • Levings, M.K.1    Bachetta, R.2    Schulz, U.3
  • 147
    • 0033136302 scopus 로고    scopus 로고
    • Thymus and autoimmunity: production of CD25 + CD4 + naturally anergic and suppressive T cells as a key function of the thymus in maintaining immunologic self-tolerance
    • Itoh M., Takahashi T., Sakaguchi N., et al. Thymus and autoimmunity: production of CD25 + CD4 + naturally anergic and suppressive T cells as a key function of the thymus in maintaining immunologic self-tolerance. J Immunol 162 (1999) 5317-5326
    • (1999) J Immunol , vol.162 , pp. 5317-5326
    • Itoh, M.1    Takahashi, T.2    Sakaguchi, N.3
  • 148
    • 0027509812 scopus 로고
    • Evidence that the T cell repertoire of normal rats contains cells with the potential to cause diabetes. Characterization of the CD4 + T cell subset that inhibits this autoimmune potential
    • Fowell D., and Mason D. Evidence that the T cell repertoire of normal rats contains cells with the potential to cause diabetes. Characterization of the CD4 + T cell subset that inhibits this autoimmune potential. J Exp Med 177 (1993) 627-636
    • (1993) J Exp Med , vol.177 , pp. 627-636
    • Fowell, D.1    Mason, D.2
  • 149
    • 0029788211 scopus 로고    scopus 로고
    • Autoimmune disease as a consequence of developmental abnormality of a T cell subpopulation
    • Asano M., Toda M., Sakaguchi N., et al. Autoimmune disease as a consequence of developmental abnormality of a T cell subpopulation. J Exp Med 184 (1996) 387-396
    • (1996) J Exp Med , vol.184 , pp. 387-396
    • Asano, M.1    Toda, M.2    Sakaguchi, N.3
  • 150
    • 0037026003 scopus 로고    scopus 로고
    • Phenotype, localization, and mechanism of suppression of CD4 + CD25 + human thymocytes
    • Annunziato F., Cosmi L., Liotta F., et al. Phenotype, localization, and mechanism of suppression of CD4 + CD25 + human thymocytes. J Exp Med 196 (2002) 379-387
    • (2002) J Exp Med , vol.196 , pp. 379-387
    • Annunziato, F.1    Cosmi, L.2    Liotta, F.3
  • 151
    • 0034679560 scopus 로고    scopus 로고
    • Immunologic self-tolerance maintained by CD25(+)CD4(+) regulatory T cells constitutively expressing cytotoxic T lymphocyte-associated antigen 4
    • Takahashi T., Tagami T., Yamazaki S., et al. Immunologic self-tolerance maintained by CD25(+)CD4(+) regulatory T cells constitutively expressing cytotoxic T lymphocyte-associated antigen 4. J Exp Med 192 (2000) 303-310
    • (2000) J Exp Med , vol.192 , pp. 303-310
    • Takahashi, T.1    Tagami, T.2    Yamazaki, S.3
  • 152
    • 0034679567 scopus 로고    scopus 로고
    • Cytotoxic T lymphocyte-associated antigen 4 plays an essential role in the function of CD25(+)CD4(+) regulatory cells that control intestinal inflammation
    • Read S., Malmstrom V., and Powrie F. Cytotoxic T lymphocyte-associated antigen 4 plays an essential role in the function of CD25(+)CD4(+) regulatory cells that control intestinal inflammation. J Exp Med 192 (2000) 295-302
    • (2000) J Exp Med , vol.192 , pp. 295-302
    • Read, S.1    Malmstrom, V.2    Powrie, F.3
  • 153
    • 0033180181 scopus 로고    scopus 로고
    • Development of lupus-like autoimmune diseases by disruption of the PD-1 gene encoding an ITIM motif-carrying immunoreceptor
    • Nishimura H., Nose M., Hiai H., et al. Development of lupus-like autoimmune diseases by disruption of the PD-1 gene encoding an ITIM motif-carrying immunoreceptor. Immunity 11 (1999) 141-151
    • (1999) Immunity , vol.11 , pp. 141-151
    • Nishimura, H.1    Nose, M.2    Hiai, H.3
  • 154
    • 0036207926 scopus 로고    scopus 로고
    • PD-1:PD-L inhibitory pathway affects both CD4(+) and CD8(+) T cells and is overcome by IL-2
    • Carter L., Fouser L.A., Jussif J., et al. PD-1:PD-L inhibitory pathway affects both CD4(+) and CD8(+) T cells and is overcome by IL-2. Eur J Immunol 32 (2002) 634-643
    • (2002) Eur J Immunol , vol.32 , pp. 634-643
    • Carter, L.1    Fouser, L.A.2    Jussif, J.3
  • 155
    • 0036195161 scopus 로고    scopus 로고
    • CD4(+)CD25(+) immunoregulatory T cells: gene expression analysis reveals a functional role for the glucocorticoid-induced TNF receptor
    • McHugh R.S., Whitters M.J., and Piccirillov C.A. CD4(+)CD25(+) immunoregulatory T cells: gene expression analysis reveals a functional role for the glucocorticoid-induced TNF receptor. Immunity 16 (2002) 311-323
    • (2002) Immunity , vol.16 , pp. 311-323
    • McHugh, R.S.1    Whitters, M.J.2    Piccirillov, C.A.3
  • 156
    • 0036170938 scopus 로고    scopus 로고
    • Stimulation of CD25(+)CD4(+) regulatory T cells through GITR breaks immunological self-tolerance
    • Shimizu J., Yamazaki S., Takahashi T., et al. Stimulation of CD25(+)CD4(+) regulatory T cells through GITR breaks immunological self-tolerance. Nat Immunol 3 (2002) 135-142
    • (2002) Nat Immunol , vol.3 , pp. 135-142
    • Shimizu, J.1    Yamazaki, S.2    Takahashi, T.3
  • 157
    • 0030962132 scopus 로고    scopus 로고
    • A new member of the tumor necrosis factor/nerve growth factor receptor family inhibits T cell receptor-induced apoptosis
    • Nocentini G., Giunchi L., Ronchetti S., et al. A new member of the tumor necrosis factor/nerve growth factor receptor family inhibits T cell receptor-induced apoptosis. Proc Natl Acad Sci USA 94 (1997) 6216-6221
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 6216-6221
    • Nocentini, G.1    Giunchi, L.2    Ronchetti, S.3
  • 158
    • 0036791004 scopus 로고    scopus 로고
    • Expression of the integrin alpha E beta 7 identifies unique subsets of CD25 + as well as CD25- regulatory T cells
    • Lehmann J., Huehn J., de la Rosa M., et al. Expression of the integrin alpha E beta 7 identifies unique subsets of CD25 + as well as CD25- regulatory T cells. Proc Natl Acad Sci USA 99 (2002) 13031-13036
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 13031-13036
    • Lehmann, J.1    Huehn, J.2    de la Rosa, M.3
  • 159
    • 0035806323 scopus 로고    scopus 로고
    • Human CD25(+)CD4(+) T regulatory cells suppress naive and memory T cell proliferation and can be expanded in vitro without loss of function
    • Levings M.K., Sangregorio R., and Roncarolo M.G. Human CD25(+)CD4(+) T regulatory cells suppress naive and memory T cell proliferation and can be expanded in vitro without loss of function. J Exp Med 193 (2001) 1295-1302
    • (2001) J Exp Med , vol.193 , pp. 1295-1302
    • Levings, M.K.1    Sangregorio, R.2    Roncarolo, M.G.3
  • 160
    • 0037385314 scopus 로고    scopus 로고
    • An essential role for Scurfin in CD4 + CD25 + T regulatory cells
    • Khattri R., Cox T., Yasayko S.A., et al. An essential role for Scurfin in CD4 + CD25 + T regulatory cells. Nat Immunol 4 (2003) 337-342
    • (2003) Nat Immunol , vol.4 , pp. 337-342
    • Khattri, R.1    Cox, T.2    Yasayko, S.A.3
  • 161
    • 0037385330 scopus 로고    scopus 로고
    • Foxp3 programs the development and function of CD4 + CD25 + regulatory T cells
    • Fontenot J.D., Gavin M.A., and Rudensky A.Y. Foxp3 programs the development and function of CD4 + CD25 + regulatory T cells. Nat Immunol 4 (2003) 330-336
    • (2003) Nat Immunol , vol.4 , pp. 330-336
    • Fontenot, J.D.1    Gavin, M.A.2    Rudensky, A.Y.3
  • 162
    • 0030069074 scopus 로고    scopus 로고
    • Disease in the scurfy (sf) mouse is associated with overexpression of cytokine genes
    • Kanangat S., Blair P., Reddy R., et al. Disease in the scurfy (sf) mouse is associated with overexpression of cytokine genes. Eur J Immunol 26 (1996) 161-165
    • (1996) Eur J Immunol , vol.26 , pp. 161-165
    • Kanangat, S.1    Blair, P.2    Reddy, R.3
  • 163
    • 0035813231 scopus 로고    scopus 로고
    • Scurfin (FOXP3) acts as a repressor of transcription and regulates T cell activation
    • Schubert L.A., Jeffrey E., Zhang Y., et al. Scurfin (FOXP3) acts as a repressor of transcription and regulates T cell activation. J Biol Chem 276 (2001) 37672-37679
    • (2001) J Biol Chem , vol.276 , pp. 37672-37679
    • Schubert, L.A.1    Jeffrey, E.2    Zhang, Y.3
  • 164
    • 0035163909 scopus 로고    scopus 로고
    • X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome is the human equivalent of mouse scurfy
    • Wildin R.S., Ramsdell F., Peake J., et al. X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome is the human equivalent of mouse scurfy. Nat Genet 27 (2001) 18-20
    • (2001) Nat Genet , vol.27 , pp. 18-20
    • Wildin, R.S.1    Ramsdell, F.2    Peake, J.3
  • 165
    • 0043244867 scopus 로고    scopus 로고
    • Antigen-dependent proliferation of CD4 + CD25 + regulatory T cells in vivo
    • Walker L.S., Chodos A., Eggena M., et al. Antigen-dependent proliferation of CD4 + CD25 + regulatory T cells in vivo. J Exp Med 198 (2003) 249-258
    • (2003) J Exp Med , vol.198 , pp. 249-258
    • Walker, L.S.1    Chodos, A.2    Eggena, M.3
  • 166
    • 0024589097 scopus 로고
    • Organ-specific autoimmune disease induced in mice by elimination of T cell subsets. V. Neonatal administration of cyclosporin A causes autoimmune disease
    • Sakaguchi S., and Sakaguchi N. Organ-specific autoimmune disease induced in mice by elimination of T cell subsets. V. Neonatal administration of cyclosporin A causes autoimmune disease. J Immunol 142 (1989) 471-480
    • (1989) J Immunol , vol.142 , pp. 471-480
    • Sakaguchi, S.1    Sakaguchi, N.2
  • 167
    • 0029150110 scopus 로고
    • Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases
    • Sakaguchi S., Sakaguchi N., Asano M., et al. Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases. J Immunol 155 (1995) 1151-1164
    • (1995) J Immunol , vol.155 , pp. 1151-1164
    • Sakaguchi, S.1    Sakaguchi, N.2    Asano, M.3
  • 168
    • 0031255003 scopus 로고    scopus 로고
    • CD4 + T-cells in the regulation of inflammatory responses in the intestine
    • Powrie F., Mauze S., and Coffman R.L. CD4 + T-cells in the regulation of inflammatory responses in the intestine. Res Immunol 148 (1997) 576-581
    • (1997) Res Immunol , vol.148 , pp. 576-581
    • Powrie, F.1    Mauze, S.2    Coffman, R.L.3
  • 169
    • 0033682056 scopus 로고    scopus 로고
    • B7/CD28 costimulation is essential for the homeostasis of the CD4 + CD25 + immunoregulatory T cells that control autoimmune diabetes
    • Salomon B., Lenschow D.J., Rhee L., et al. B7/CD28 costimulation is essential for the homeostasis of the CD4 + CD25 + immunoregulatory T cells that control autoimmune diabetes. Immunity 12 (2000) 431-440
    • (2000) Immunity , vol.12 , pp. 431-440
    • Salomon, B.1    Lenschow, D.J.2    Rhee, L.3
  • 170
    • 0037446531 scopus 로고    scopus 로고
    • Cutting edge: cure of colitis by CD4 + CD25 + regulatory T cells
    • Mottet C., Uhlig H.H., and Powrie F. Cutting edge: cure of colitis by CD4 + CD25 + regulatory T cells. J Immunol 170 (2003) 3939-3943
    • (2003) J Immunol , vol.170 , pp. 3939-3943
    • Mottet, C.1    Uhlig, H.H.2    Powrie, F.3
  • 171
    • 0035903324 scopus 로고    scopus 로고
    • Synergism of cytotoxic T lymphocyte-associated antigen 4 blockade and depletion of CD25(+) regulatory T cells in antitumor therapy reveals alternative pathways for suppression of autoreactive cytotoxic T lymphocyte responses
    • Sutmuller R.P., van Duivenvoorde L.M., van Elsas A., et al. Synergism of cytotoxic T lymphocyte-associated antigen 4 blockade and depletion of CD25(+) regulatory T cells in antitumor therapy reveals alternative pathways for suppression of autoreactive cytotoxic T lymphocyte responses. J Exp Med 194 (2001) 823-832
    • (2001) J Exp Med , vol.194 , pp. 823-832
    • Sutmuller, R.P.1    van Duivenvoorde, L.M.2    van Elsas, A.3
  • 172
    • 0033571105 scopus 로고    scopus 로고
    • Induction of tumor immunity by removing CD25 + CD4 + T cells: a common basis between tumor immunity and autoimmunity
    • Shimizu J., Yamazaki S., and Sakaguchi S. Induction of tumor immunity by removing CD25 + CD4 + T cells: a common basis between tumor immunity and autoimmunity. J Immunol 163 (1999) 5211-5218
    • (1999) J Immunol , vol.163 , pp. 5211-5218
    • Shimizu, J.1    Yamazaki, S.2    Sakaguchi, S.3
  • 174
    • 0037999835 scopus 로고    scopus 로고
    • Histamine in the immune regulation of allergic inflammation
    • Akdis C.A., and Blaser K. Histamine in the immune regulation of allergic inflammation. J Allergy Clin Immunol 112 (2003) 15-22
    • (2003) J Allergy Clin Immunol , vol.112 , pp. 15-22
    • Akdis, C.A.1    Blaser, K.2
  • 175
    • 0030664856 scopus 로고    scopus 로고
    • Novel insights into histamine H2 receptor biology
    • Del Valle J., and Gantz I. Novel insights into histamine H2 receptor biology. Am J Physiol 273 (1997) G987-G996
    • (1997) Am J Physiol , vol.273
    • Del Valle, J.1    Gantz, I.2
  • 176
    • 0035668614 scopus 로고    scopus 로고
    • Histamine regulates cytokine production in maturing dendritic cells, resulting in altered T cell polarization
    • Mazzoni A., Young H.A., Spitzer J.H., et al. Histamine regulates cytokine production in maturing dendritic cells, resulting in altered T cell polarization. J Clin Invest 108 (2001) 1865-1873
    • (2001) J Clin Invest , vol.108 , pp. 1865-1873
    • Mazzoni, A.1    Young, H.A.2    Spitzer, J.H.3
  • 177
    • 0035124146 scopus 로고    scopus 로고
    • Regulation of interleukin-10 secretion by histamine in TH2 cells and splenocytes
    • Osna N., Elliott K., and Khan M.M. Regulation of interleukin-10 secretion by histamine in TH2 cells and splenocytes. Int Immunopharmacol 1 (2001) 85-96
    • (2001) Int Immunopharmacol , vol.1 , pp. 85-96
    • Osna, N.1    Elliott, K.2    Khan, M.M.3
  • 178
    • 0037709966 scopus 로고    scopus 로고
    • Histamine enhances TGF-beta1-mediated suppression of Th2 responses
    • Kunzmann S., Mantel P.-Y., Wohlfahrt J., et al. Histamine enhances TGF-beta1-mediated suppression of Th2 responses. FASEB J 17 (2003) 1089-1095
    • (2003) FASEB J , vol.17 , pp. 1089-1095
    • Kunzmann, S.1    Mantel, P.-Y.2    Wohlfahrt, J.3
  • 179
    • 0035141765 scopus 로고    scopus 로고
    • Premedication with antihistamines may enhance efficacy of specific- allergen immunotherapy
    • Müller U., Hari Y., and Berchtold E. Premedication with antihistamines may enhance efficacy of specific- allergen immunotherapy. J Allergy Clin Immunol 107 (2001) 81-86
    • (2001) J Allergy Clin Immunol , vol.107 , pp. 81-86
    • Müller, U.1    Hari, Y.2    Berchtold, E.3
  • 180
    • 0006267373 scopus 로고    scopus 로고
    • Histamine receptor expression on peripheral blood CD4 + lymphocytes is influenced by ultrarush bee venom immunotherapy
    • Jutel M., Zak-Nejmark T., Wrzyyszcz M., et al. Histamine receptor expression on peripheral blood CD4 + lymphocytes is influenced by ultrarush bee venom immunotherapy. Allergy 52 Suppl 37 (1997) 88
    • (1997) Allergy , vol.52 , Issue.SUPPL. 37 , pp. 88
    • Jutel, M.1    Zak-Nejmark, T.2    Wrzyyszcz, M.3


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