PD-1:PD-L inhibitory pathway affects both CD4+ and CD8+ T cells and is overcome by IL-2

European Journal of Immunology

Volumn 32, Issue 3, 2002, Pages 634-643

  Carter, Laura L ^a   Fouser, Lynette A ^a   Jussif, Jason ^a   Fitz, Lori ^a   Deng, Bija ^a   Wood, Clive R ^a   Collins, Mary ^a   Honjo, Tasuku ^b   Freeman, Gordon J ^c   Carreno, Beatriz M ^a  

^a PFIZER INC   (United States)

^b KYOTO UNIVERSITY   (Japan)

^c HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Inhibitory receptor; PD 1; PD L1

Indexed keywords

APOPTOSIS INHIBITOR; B7 ANTIGEN; CD28 ANTIGEN; CD4 ANTIGEN; CD8 ANTIGEN; INTERLEUKIN 2; LIGAND; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY CD3;

ANIMAL CELL; APOPTOSIS; ARTICLE; AUTOIMMUNE DISEASE; CELL DIVISION; CELL INTERACTION; CELL PROLIFERATION; CELL STIMULATION; CELL TRANSPORT; CONTROLLED STUDY; CYTOKINE PRODUCTION; FEMALE; IMMUNE RESPONSE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FAMILY; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN MOTIF; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION;

AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES, MONOCLONAL; ANTIGEN PRESENTATION; ANTIGENS, CD29; ANTIGENS, CD3; ANTIGENS, CD80; ANTIGENS, SURFACE; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; BLOOD PROTEINS; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CELL DIVISION; CELL LINE; FEMALE; IMMUNOGLOBULIN FC FRAGMENTS; INTERLEUKIN-2; KINETICS; LIGANDS; LYMPHOCYTE ACTIVATION; MEMBRANE GLYCOPROTEINS; MICE; MICE, INBRED BALB C; MICE, TRANSGENIC; MICROSPHERES; MOLECULAR SEQUENCE DATA; PEPTIDES; PROTEINS; RECEPTORS, ANTIGEN, T-CELL;

EID: 0036207926     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/1521-4141(200203)32:3<634::AID-IMMU634>3.0.CO;2-9     Document Type: Article

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