메뉴 건너뛰기




Volumn 30, Issue 6, 2000, Pages 1683-1690

IL-10 directly acts on T cells by specifically altering the CD28 co-stimulation pathway

Author keywords

CD28; IL 10; Phosphatidylinositol 3 kinase; Suppression; T lymphocyte

Indexed keywords

CD28 ANTIGEN; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 13; INTERLEUKIN 2; INTERLEUKIN 4; INTERLEUKIN 5; MONOCLONAL ANTIBODY; PHOSPHATIDYLINOSITOL 3 KINASE; SUPERANTIGEN;

EID: 0034039840     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/1521-4141(200006)30:6<1683::AID-IMMU1683>3.0.CO;2-A     Document Type: Article
Times cited : (191)

References (47)
  • 1
  • 2
    • 0025322552 scopus 로고
    • T-cell antigen CD28 mediates adhesion with B cells by interacting with activation antigen B7/BB-1
    • Linsley, P. S., Clark, E. A., and Ledbetter, J.A., T-cell antigen CD28 mediates adhesion with B cells by interacting with activation antigen B7/BB-1. Proc. Natl. Acad. Sci. USA 1990. 87: 5031-5035.
    • (1990) Proc. Natl. Acad. Sci. USA , vol.87 , pp. 5031-5035
    • Linsley, P.S.1    Clark, E.A.2    Ledbetter, J.A.3
  • 3
    • 0025963594 scopus 로고
    • Binding of the B cell activation antigen B7 to CD28 costimulates T cell proliferation and interleukin2 mRNA accumulation
    • Linsley, P. S., Brady, W., Grosmaire, L., Aruffo, A., Damle, N. K. and Ledbetter, J. A., Binding of the B cell activation antigen B7 to CD28 costimulates T cell proliferation and interleukin2 mRNA accumulation. J. Exp. Med. 1991. 173: 721-730.
    • (1991) J. Exp. Med. , vol.173 , pp. 721-730
    • Linsley, P.S.1    Brady, W.2    Grosmaire, L.3    Aruffo, A.4    Damle, N.K.5    Ledbetter, J.A.6
  • 5
    • 0027397169 scopus 로고
    • Induction of alloantigen-specific hyporesponsiveness in human T lymphocytes by blocking interaction of CD28 with its natural ligand B7/BB1
    • Tan, P., Anasetti, C., Hansen, J. A., Melrose, J., Brunvand, M., Bradshaw, J., Ledbetter, J. A. and Linsley, P. S. Induction of alloantigen-specific hyporesponsiveness in human T lymphocytes by blocking interaction of CD28 with its natural ligand B7/BB1.J. Exp. Med. 1993. 177: 165-173.
    • (1993) J. Exp. Med. , vol.177 , pp. 165-173
    • Tan, P.1    Anasetti, C.2    Hansen, J.A.3    Melrose, J.4    Brunvand, M.5    Bradshaw, J.6    Ledbetter, J.A.7    Linsley, P.S.8
  • 6
    • 0026537347 scopus 로고
    • CD28-mediated signaling co-stimulates murine T cells and prevents induction of anergy in T-cell clones
    • Harding, F. A., McArthur, J. G., Gross, J. A., Raulet, D. H. and Allison, J. P., CD28-mediated signaling co-stimulates murine T cells and prevents induction of anergy in T-cell clones. Nature 1992. 356: 607-609.
    • (1992) Nature , vol.356 , pp. 607-609
    • Harding, F.A.1    McArthur, J.G.2    Gross, J.A.3    Raulet, D.H.4    Allison, J.P.5
  • 7
    • 0028182749 scopus 로고
    • Binding of phosphatidyl-inositol-3-OH kinase to CD28 is required for T-cell signaling
    • Pagès, F., Ragueneau, M, Rottapel, R., Truneh, A., Nunes, J., Imbert, J. and Olive, D., Binding of phosphatidyl-inositol-3-OH kinase to CD28 is required for T-cell signaling. Nature 1994. 369: 327-329.
    • (1994) Nature , vol.369 , pp. 327-329
    • Pagès, F.1    Ragueneau, M.2    Rottapel, R.3    Truneh, A.4    Nunes, J.5    Imbert, J.6    Olive, D.7
  • 8
    • 0028221022 scopus 로고
    • T-cell antigen CD28 interacts with the lipid kinase phosphatidylinositol 3-kinase by a cytoplasmic tyr(P)-Met-Xaa-Met motif
    • Prasad, K. V., Cai, Y-C., Raab, M., Duckworth, B., Cantley, L., Shoelson, S. and Rudd, C. E., T-cell antigen CD28 interacts with the lipid kinase phosphatidylinositol 3-kinase by a cytoplasmic Tyr(P)-Met-Xaa-Met motif. Proc. Natl. Acad. Sci. USA 1994. 91: 2834-2838.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 2834-2838
    • Prasad, K.V.1    Cai, Y.-C.2    Raab, M.3    Duckworth, B.4    Cantley, L.5    Shoelson, S.6    Rudd, C.E.7
  • 9
    • 0029965232 scopus 로고    scopus 로고
    • Pl 3-kinase: A pivotal pathway in T-cell activation?
    • Ward, S. G., June, C. H. and Olive, D., Pl 3-kinase: a pivotal pathway in T-cell activation?. Immunol. Today 1996. 17: 187-197.
    • (1996) Immunol. Today , vol.17 , pp. 187-197
    • Ward, S.G.1    June, C.H.2    Olive, D.3
  • 10
    • 0024408824 scopus 로고
    • Two types of mouse T helper cell. IV. Th2 clones secrete a factor that inhibits cytokine production by Th1 clones
    • Fiorentino, D. F., Bond, M. W. and Mosmann, T. R., Two types of mouse T helper cell. IV. Th2 clones secrete a factor that inhibits cytokine production by Th1 clones. J. Exp. Med. 1989. 170: 2081-2095.
    • (1989) J. Exp. Med. , vol.170 , pp. 2081-2095
    • Fiorentino, D.F.1    Bond, M.W.2    Mosmann, T.R.3
  • 11
    • 0026094306 scopus 로고
    • Interleukin 10 (IL-10) inhibits cytokine synthesis by human monocytes: An autoregulalory role of IL-10 produced by monocytes
    • de Waal Malefyt, R., Abrams, J., Bennett, B., Figdor, C. G. and Vries, J. E., Interleukin 10 (IL-10) inhibits cytokine synthesis by human monocytes: An autoregulalory role of IL-10 produced by monocytes. J. Exp. Med. 1991. 174: 1209-1220.
    • (1991) J. Exp. Med. , vol.174 , pp. 1209-1220
    • De Waal Malefyt, R.1    Abrams, J.2    Bennett, B.3    Figdor, C.G.4    Vries, J.E.5
  • 13
    • 0026514309 scopus 로고
    • Differential effects of IL-4 and IL-10 on IL-2-induced IFN-gamma synthesis and lymphokine-activated killer activity
    • Hsu, D.-H., Moore, K. W. and Spits, H., Differential effects of IL-4 and IL-10 on IL-2-induced IFN-gamma synthesis and lymphokine-activated killer activity. Int. Immunol. 1992. 4: 563-569.
    • (1992) Int. Immunol. , vol.4 , pp. 563-569
    • Hsu, D.-H.1    Moore, K.W.2    Spits, H.3
  • 15
    • 0028158319 scopus 로고
    • High levels of interleukin 10 production in vivo are associated with tolerance in scid patients transplanted with HLA mismatched hematopoietic stem cells
    • Bacchetta, R., Bigler, M., Touraine, J.-L., Parkman, R., Tovo, P.-A., Abrams, J., de Waal Malefyt, R., de Vries, J. E. and Roncarolo, M.-G., High levels of interleukin 10 production in vivo are associated with tolerance in SCID patients transplanted with HLA mismatched hematopoietic stem cells. J. Exp. Med. 1994. 179: 493-502.
    • (1994) J. Exp. Med. , vol.179 , pp. 493-502
    • Bacchetta, R.1    Bigler, M.2    Touraine, J.-L.3    Parkman, R.4    Tovo, P.-A.5    Abrams, J.6    De Waal Malefyt, R.7    De Vries, J.E.8    Roncarolo, M.-G.9
  • 16
    • 0027960758 scopus 로고
    • Maintenance of clonal anergy by endogeneously produced IL-10
    • Becker, J. C., Czerny, C. and Bröcker, E.-B. Maintenance of clonal anergy by endogeneously produced IL-10. Int. Immunol. 1994. 6: 1605-1612.
    • (1994) Int. Immunol. , vol.6 , pp. 1605-1612
    • Becker, J.C.1    Czerny, C.2    Bröcker, E.-B.3
  • 19
    • 0027204621 scopus 로고
    • Human IL-10 is produced by both type 1 helper (Th1) and type 2 helper (Th2) T cell clones and inhibits their antigen-specific proliferation and cytokine production
    • Del Prete, G., de Carli, M., Almerigogna, F., Giudizi, M. G., Biagiotti, R. and Romagnani, S., Human IL-10 is produced by both type 1 helper (Th1) and type 2 helper (Th2) T cell clones and inhibits their antigen-specific proliferation and cytokine production. J. Immunol. 1993. 150: 363-360.
    • (1993) J. Immunol. , vol.150 , pp. 363-1360
    • Del Prete, G.1    De Carli, M.2    Almerigogna, F.3    Giudizi, M.G.4    Biagiotti, R.5    Romagnani, S.6
  • 20
    • 0026000892 scopus 로고
    • Interleukin 10 (IL-10) and viral IL-10 strongly reduce antigen-specific human T cell proliferation by diminishing the antigen-presenting capacity of monocytes via downregulation of class II major histocompatibility complex expression
    • de Waal Malefyt, R., Haanen, J., Spits, H., Roncarolo, M.-G., te Velde, A., Figdor, C. G., Johnson, K. E., Kastelein, R., Yssel, H. and de Vries, J. E., Interleukin 10 (IL-10) and viral IL-10 strongly reduce antigen-specific human T cell proliferation by diminishing the antigen-presenting capacity of monocytes via downregulation of class II major histocompatibility complex expression. J. Exp. Med. 1991. 174: 915-924.
    • (1991) J. Exp. Med. , vol.174 , pp. 915-924
    • De Waal Malefyt, R.1    Haanen, J.2    Spits, H.3    Roncarolo, M.-G.4    Te Velde, A.5    Figdor, C.G.6    Johnson, K.E.7    Kastelein, R.8    Yssel, H.9    De Vries, J.E.10
  • 21
    • 0029034075 scopus 로고
    • Comparative analysis of B7-1 and B7-2 expression in Langerhans cells: Differential regulation by T helper type 1 and T helper type 2 cytokines
    • Kawamura, T. and Furue, M., Comparative analysis of B7-1 and B7-2 expression in Langerhans cells: differential regulation by T helper type 1 and T helper type 2 cytokines. Eur. J. Immunol. 1995. 25: 1913-1917.
    • (1995) Eur. J. Immunol. , vol.25 , pp. 1913-1917
    • Kawamura, T.1    Furue, M.2
  • 22
    • 0028948225 scopus 로고
    • Psoriatic skin-derived dendritic cell function is inhibited by exogenous IL-10. Differential modulation of B7-1 (CD80) and B7-2 (CD86) expression
    • Mitra, R. S., Judge., T. A., Nestle, F. O., Turka, L. A. and Nickoloff, B. J., Psoriatic skin-derived dendritic cell function is inhibited by exogenous IL-10. Differential modulation of B7-1 (CD80) and B7-2 (CD86) expression. J. Immunol. 1995. 154: 2668-2677.
    • (1995) J. Immunol. , vol.154 , pp. 2668-2677
    • Mitra, R.S.1    Judge, T.A.2    Nestle, F.O.3    Turka, L.A.4    Nickoloff, B.J.5
  • 24
    • 0027239842 scopus 로고
    • IL-10 inhibits macrophage costimulatory activity by selectively inhibiting the up-regulation of B7 expression
    • Ding, L., Linsley, P. S., Huang, L. Y., Germain, R. N. and Shevach, E. M., IL-10 inhibits macrophage costimulatory activity by selectively inhibiting the up-regulation of B7 expression. J. Immunol. 1993. 151: 1224-1234.
    • (1993) J. Immunol. , vol.151 , pp. 1224-1234
    • Ding, L.1    Linsley, P.S.2    Huang, L.Y.3    Germain, R.N.4    Shevach, E.M.5
  • 25
    • 0033977156 scopus 로고    scopus 로고
    • High-sensitivity immunofluorescence for detection of the pro- and anti-inflammatory cytokines gamma interferon and interleukin-10 on the surface of cytokine-secreting cells
    • Scheffold, A., Assenmacher, M., Reiners-Schramm., L., Lauster, R. and Radbruch, A., High-sensitivity immunofluorescence for detection of the pro- and anti-inflammatory cytokines gamma interferon and interleukin-10 on the surface of cytokine-secreting cells. Nature Med. 2000. : 107-110.
    • (2000) Nature Med. , pp. 107-110
    • Scheffold, A.1    Assenmacher, M.2    Reiners-Schramm, L.3    Lauster, R.4    Radbruch, A.5
  • 26
    • 0032502801 scopus 로고    scopus 로고
    • Homeostasis and self-tolerance the immune system: Turning lymphocytes off
    • Parijs, L. V. and Abbas, A. K., Homeostasis and self-tolerance the immune system: turning lymphocytes off. Science 1998. 280: 243-248.
    • (1998) Science , vol.280 , pp. 243-248
    • Parijs, L.V.1    Abbas, A.K.2
  • 27
    • 0023914792 scopus 로고
    • Interleukin-2 can prevent and reverse antigen-induced unresponsiveness in cloned human T lymphocytes
    • Essery, ., Feldman, M. and Lamb, J. R., Interleukin-2 can prevent and reverse antigen-induced unresponsiveness in cloned human T lymphocytes. Immunology 1988. 64: 413-417.
    • (1988) Immunology , vol.64 , pp. 413-417
    • Essery1    Feldman, M.2    Lamb, J.R.3
  • 28
    • 0030025598 scopus 로고    scopus 로고
    • Comparison of CD28-B7.1 and B7.2 functional interaction in resting human T cells: Phosphatidylinositol 3-kinase association to CD28 and cytokine production
    • Ghiotto-Ragueneau, M., Battifora, M., Truneh, A., Waterfield, M. D. and Olive, D., Comparison of CD28-B7.1 and B7.2 functional interaction in resting human T cells: phosphatidylinositol 3-kinase association to CD28 and cytokine production. Eur. J. Immunol. 1996. 26: 34-41.
    • (1996) Eur. J. Immunol. , vol.26 , pp. 34-41
    • Ghiotto-Ragueneau, M.1    Battifora, M.2    Truneh, A.3    Waterfield, M.D.4    Olive, D.5
  • 29
    • 0030057218 scopus 로고    scopus 로고
    • T cell activation determined by T cell receptor number and tunable thresholds
    • Viola, A. and Lanzavecchia, A., T cell activation determined by T cell receptor number and tunable thresholds. Science 1996. 273: 104-106.
    • (1996) Science , vol.273 , pp. 104-106
    • Viola, A.1    Lanzavecchia, A.2
  • 30
    • 0023143676 scopus 로고
    • Antigen presentation by chemically modified splenocytes induces antigen-specific T cell unresponsiveness in vitro and in vivo
    • Jenkins, M. K. and Schwartz, R., Antigen presentation by chemically modified splenocytes induces antigen-specific T cell unresponsiveness in vitro and in vivo. J. Exp. Med. 1987. 165: 302-319.
    • (1987) J. Exp. Med. , vol.165 , pp. 302-319
    • Jenkins, M.K.1    Schwartz, R.2
  • 31
    • 0020569052 scopus 로고
    • Induction of tolerance in influenza virus-immune T lymphocyte clones with synthetic peptides of influenza hemagglutinin
    • Lamb, J.R., Skidmore, N., Green, N., Chiller, J. M. and Feldman, M., Induction of tolerance in influenza virus-immune T lymphocyte clones with synthetic peptides of influenza hemagglutinin. J. Exp. Med. 1983. 157: 1434-1447.
    • (1983) J. Exp. Med. , vol.157 , pp. 1434-1447
    • Lamb, J.R.1    Skidmore, N.2    Green, N.3    Chiller, J.M.4    Feldman, M.5
  • 32
    • 0026687519 scopus 로고
    • Reversal of in vitro T cell clonal anergy by IL-2 stimulation
    • Beverly, B., Kang, S.-M., Lenardo, M. J. and Schwartz, R. H., Reversal of in vitro T cell clonal anergy by IL-2 stimulation. Int. Immunol. 1992. 4: 661-671.
    • (1992) Int. Immunol. , vol.4 , pp. 661-671
    • Beverly, B.1    Kang, S.-M.2    Lenardo, M.J.3    Schwartz, R.H.4
  • 33
    • 0026316280 scopus 로고
    • Clonal anergy blocks the response to IL-4, as well as the production of IL-2 in dual-producing helper T cell clones
    • Müller, D. L., Chiodetti, L., Bacon, P. A. and Schwartz, R. H., Clonal anergy blocks the response to IL-4, as well as the production of IL-2 in dual-producing helper T cell clones. J. Immunol 1991. 147: 4118-4125.
    • (1991) J. Immunol , vol.147 , pp. 4118-4125
    • Müller, D.L.1    Chiodetti, L.2    Bacon, P.A.3    Schwartz, R.H.4
  • 35
    • 0033083289 scopus 로고    scopus 로고
    • An altered peptide ligand specifically inhibits Th2 cytokine synthesis by abrogating TCR signaling
    • Faith, A., Akdis, C. A., Akdis, M., Joss, A., Wymann, D. and Blaser, K., An altered peptide ligand specifically inhibits Th2 cytokine synthesis by abrogating TCR signaling. J. Immunol. 1999. 162: 1836-1842.
    • (1999) J. Immunol. , vol.162 , pp. 1836-1842
    • Faith, A.1    Akdis, C.A.2    Akdis, M.3    Joss, A.4    Wymann, D.5    Blaser, K.6
  • 37
    • 0032921181 scopus 로고    scopus 로고
    • IL-10 induced anergy in peripheral T cell and reactivation by microenvironmental cytokines: Two key steps in specific immunotherapy
    • Akdis, C. A. and Blaser, K., IL-10 induced anergy in peripheral T cell and reactivation by microenvironmental cytokines: Two key steps in specific immunotherapy. FASEB J. 1999. 13: 603-609.
    • (1999) FASEB J. , vol.13 , pp. 603-609
    • Akdis, C.A.1    Blaser, K.2
  • 38
    • 0031569098 scopus 로고    scopus 로고
    • CD28 ligation prevents bacterial toxin-induced septic shock in mice by inducing IL-10 expression
    • Wang, R., Fang, Q., Zhang, L., Radvany, L., Sharma, A., Noben-Trauth, N., Mills, G. B. and Shi, Y., CD28 ligation prevents bacterial toxin-induced septic shock in mice by inducing IL-10 expression. J. Immunol. 1997. 158: 2856-2861.
    • (1997) J. Immunol. , vol.158 , pp. 2856-2861
    • Wang, R.1    Fang, Q.2    Zhang, L.3    Radvany, L.4    Sharma, A.5    Noben-Trauth, N.6    Mills, G.B.7    Shi, Y.8
  • 39
    • 0032960255 scopus 로고    scopus 로고
    • Mechanism of interleukin-10 inhibition of T-helper cell activation by superantigen at the level of the cell cycle
    • Perrin, G. Q., Johnson, H. M. and Subramaniam, P. S., Mechanism of interleukin-10 inhibition of T-helper cell activation by superantigen at the level of the cell cycle. Blood 1999. 93: 208-216.
    • (1999) Blood , vol.93 , pp. 208-216
    • Perrin, G.Q.1    Johnson, H.M.2    Subramaniam, P.S.3
  • 40
    • 0029118395 scopus 로고
    • IL-10 induces the tyrosine phosphorylation of tyk2 and Jak1 and the differential assembly of STAT1α and STAT3 complexes in human T cells and monocytes
    • Finbloom, D. S. and Winestock, K. D., IL-10 induces the tyrosine phosphorylation of tyk2 and Jak1 and the differential assembly of STAT1α and STAT3 complexes in human T cells and monocytes. J. Immunol. 1995. 155: 1079-1090.
    • (1995) J. Immunol. , vol.155 , pp. 1079-1090
    • Finbloom, D.S.1    Winestock, K.D.2
  • 45
    • 0031567973 scopus 로고    scopus 로고
    • The Epstein-Barr virus interleukin-10 (IL-10) homolog is a selective agonist with impaired binding to the IL-10 receptor
    • Liu, Y., de Waal Malefyt, R., Briere, R, Parham, C., Bridon, J.-M., Banchereau, J., Moore, K. W. and Xu, J., The Epstein-Barr virus interleukin-10 (IL-10) homolog is a selective agonist with impaired binding to the IL-10 receptor. J. Immunol. 1997. 158: 604-613.
    • (1997) J. Immunol. , vol.158 , pp. 604-613
    • Liu, Y.1    De Waal Malefyt, R.2    Briere, R.3    Parham, C.4    Bridon, J.-M.5    Banchereau, J.6    Moore, K.W.7    Xu, J.8
  • 46
    • 0031278414 scopus 로고    scopus 로고
    • Skin-homing, CLA+ memory T cells are activated in atopic dermatitis and regulate IgE by an IL-13-dominated cytokine pattern
    • Akdis, M., Akdis, C. A., Weigl, L., Disch, R. and Blaser, K., Skin-homing, CLA+ memory T cells are activated in atopic dermatitis and regulate IgE by an IL-13-dominated cytokine pattern. J. Immunol. 1997. 159: 4611-4619.
    • (1997) J. Immunol. , vol.159 , pp. 4611-4619
    • Akdis, M.1    Akdis, C.A.2    Weigl, L.3    Disch, R.4    Blaser, K.5
  • 47


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.