CD4+ regulatory T cells

Current Opinion in Immunology

Volumn 13, Issue 6, 2001, Pages 644-649

  Read, S ^a   Powrie, F ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; CYTOKINE; IMMUNOSUPPRESSIVE AGENT;

CELL CONTACT; CELL FUNCTION; CELL LINE; HUMAN; IMMUNE MEDIATED INJURY; IMMUNE RESPONSE; IMMUNOPATHOLOGY; NONHUMAN; REGULATORY MECHANISM; REVIEW; T LYMPHOCYTE; THYMUS;

EID: 0035546070     PISSN: 09527915     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0952-7915(01)00273-4     Document Type: Review

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2. + naturally anergic and suppressive T cells: Induction of autoimmune disease by breaking their anergic/suppressive state
3. + Immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production
4. Regulatory T cell clones induced by oral tolerance: Suppression of autoimmune encephalomyelitis
5. + T cells
6. Anergic T cells as suppressor cells in vitro
7. The role of different subsets of T regulatory cells in controlling autoimmunity
8. Regulatory T cells in autoimmmunity
9. Policing the regulators
10. Regulatory T cells in the control of immune pathology
11. Autoimmune oophoritis in thymectomized mice: T cell requirement in adoptive cell transfer
12. Murine autoimmune oophoritis, epididymoorchitis, and gastritis induced by day 3 thymectomy. Immunopathology
13. + T cell subset that inhibits this autoimmune potential
14. + immunoregulatory T cells that control autoimmune diabetes
15. - subpopulations
16. + regulatory cells that control intestinal inflammation
17. + T cells: A common basis between tumor immunity and autoimmunity
18. + T cells regulate the expansion of peripheral CD4 T cells through the production of IL-10
19. IL-10 is required for regulatory T cells to mediate tolerance to alloantigens in vivo
20. + immune regulatory cells are required for induction of tolerance to alloantigen via costimulatory blockade
21. + thymocytes and peripheral T cells have immune suppressive activity in vitro
22. + T cells: A highly differentiated and apoptosis-prone population
23. + T cells with regulatory properties isolated from peripheral blood
24. + T regulatory cells suppress naive and memory T cell proliferation and can be expanded in vitro without loss of function
25. + T cells with regulatory properties from human blood
26. high regulatory cells in human peripheral blood
27. Biology of the interleukin-2 receptor
28. Recognition and function of Vα14 NKT cells
29. Activation of natural killer T cells by alpha-galactosylceramide in the presence of CD1d provides protection against colitis in mice
30. Germ line deletion of the CD1 locus exacerbates diabetes in the NOD mouse
31. CD1-restricted NK T cells protect nonobese diabetic mice from developing diabetes
32. Activation of natural killer T cells by alpha-galactosylceramide treatment prevents the onset and recurrence of autoimmune Type 1 diabetes
33. The natural killer T-cell ligand alpha-galactosylceramide prevents autoimmune diabetes in non-obese diabetic mice
34. + T-cell subset inhibits antigen-specific T-cell responses and prevents colitis
35. T regulatory cells 1 inhibit a Th2-specific response in vivo
36. IFN-alpha and IL-10 induce the differentiation of human type 1 T regulatory cells
37. Oral tolerance: Mechanisms and therapeutic applications
38. Anergic T cells act as suppressor cells in vitro and in vivo
39. Anergic T cells actively suppress T cell responses via the antigen-presenting cell
40. Anergic T cells inhibit the antigen-presenting function of dendritic cells
41. + naturally anergic and suppressive T cells as a key function of the thymus in maintaining immunologic self-tolerance
42. Control of intestinal inflammation by regulatory T cells
43. + T cell responses to a self peptide
44. + regulatory T cells induced by an agonist self-peptide
45. A model for developmentally acquired thymus-dependent tolerance to central and peripheral antigens
46. Peripheral-antigen-expressing cells in thymic medulla: Factors in self-tolerance and autoimmunity
47. Shaping of the autoreactive T-cell repertoire by a splice variant of self protein expressed in thymic epithelial cells
48. + immunoregulatory T cells
49. + T cells in vivo after induction of peripheral tolerance with intravenous or oral antigen
50. Induction of interleukin 10-producing, nonproliferating CD4(+) T cells with regulatory properties by repetitive stimulation with allogeneic immature human dendritic cells
51. Antigen-specific inhibition of effector T cell function in humans after injection of immature dendritic cells
52. Induction of tolerance by IL-10-treated dendritic cells
53. Induction of human T helper cell type 1 differentiation results in loss of IFN-gamma receptor beta-chain expression
54. Regulatory T cells induced by 1α,25-dihydroxyvitamin D3 and mycophenolate mofetil treatment mediate transplantation tolerance
55. 1 α,25-dihydroxyvitamin D3 inhibits differentiation, maturation, activation, and survival of dendritic cells leading to impaired alloreactive T cell activation
56. Pulmonary dendritic cells producing IL-10 mediate tolerance induced by respiratory exposure to antigen
57. Peptide-induced T cell regulation of experimental autoimmune encephalomyelitis: A role for IL-10
58. Suppressor T cells generated by oral tolerization to myelin basic protein suppress both in vitro and in vivo immune responses by the release of transforming growth factor beta after antigen-specific triggering
59. Peripheral autoantigen induces regulatory T cells that prevent autoimmunity
60. Persistence of physiological self antigen is required for the regulation of self tolerance
61. Regulatory CD4 T cells: Expression of IL-2R alpha chain, resistance to clonal deletion and IL-2 dependency
62. Increased T cell autoreactivity in the absence of CD40-CD40 ligand interactions: A role of CD40 in regulatory T cell development
63. B7 interactions with CD28 and CTLA-4 control tolerance or induction of mucosal inflammation in chronic experimental colitis
64. + regulatory T cells from human peripheral blood
65. + immunoregulatory T cells is antigen nonspecific
66. + immunoregulatory cells
67. + regulatory T cells down-regulate co-stimulatory molecules on antigen-presenting cells
68. Anergic' T cells modulate the T-cell activating capacity of antigen-presenting cells
69. CD152 ligation by CD80 on T cells is required for the induction of unresponsiveness by costimulation-deficient antigen presentation
70. + regulatory T cells constitutively expressing cytotoxic T lymphocyte-associated antigen 4
71. + T cells
72. + regulatory T cells is mediated by cell surface-bound transforming growth factor β
73. An essential role for interleukin 10 in the function of regulatory T cells that inhibit intestinal inflammation
74. CD134L expression on dendritic cells in the mesenteric lymph nodes drives colitis in T cell-restored SCID mice
75. Interleukin-10-deficient mice develop chronic enterocolitis
76. Abrogation of TGFβ signalling in T cells leads to spontaneous T cell differentiation and autoimmune disease