-
1
-
-
0025095550
-
Role of lymphotoxin in expression of interleukin 6 in human fibroblasts. Stimulation and regulation
-
Akashi M., Loussararian A.H., Adelman D.C., Saito M., and Koeffler H.P. Role of lymphotoxin in expression of interleukin 6 in human fibroblasts. Stimulation and regulation. J. Clin. Invest. 85 (1990) 121-129
-
(1990)
J. Clin. Invest.
, vol.85
, pp. 121-129
-
-
Akashi, M.1
Loussararian, A.H.2
Adelman, D.C.3
Saito, M.4
Koeffler, H.P.5
-
2
-
-
0037101945
-
Stressful initiations
-
Anderson P., and Kedersha N. Stressful initiations. J. Cell Sci. 115 (2002) 3227-3234
-
(2002)
J. Cell Sci.
, vol.115
, pp. 3227-3234
-
-
Anderson, P.1
Kedersha, N.2
-
3
-
-
0036556757
-
Visibly stressed: The role of eIF2, TIA-1, and stress granules in protein translation
-
Anderson P., and Kedersha N. Visibly stressed: The role of eIF2, TIA-1, and stress granules in protein translation. Cell Stress Chaperones 7 (2002) 213-221
-
(2002)
Cell Stress Chaperones
, vol.7
, pp. 213-221
-
-
Anderson, P.1
Kedersha, N.2
-
4
-
-
0030867877
-
Embryonic lethal abnormal visual RNA-binding proteins involved in growth, differentiation, and posttranscriptional gene expression
-
Antic D., and Keene J.D. Embryonic lethal abnormal visual RNA-binding proteins involved in growth, differentiation, and posttranscriptional gene expression. Am. J. Hum. Genet. 61 (1997) 273-278
-
(1997)
Am. J. Hum. Genet.
, vol.61
, pp. 273-278
-
-
Antic, D.1
Keene, J.D.2
-
5
-
-
0141889091
-
Regulation of eotaxin gene expression by TNF-alpha and IL-4 through mRNA stabilization: Involvement of the RNA-binding protein HuR
-
Atasoy U., Curry S.L., Lopez de Silanes I., Shyu A.B., Casolaro V., Gorospe M., and Stellato C. Regulation of eotaxin gene expression by TNF-alpha and IL-4 through mRNA stabilization: Involvement of the RNA-binding protein HuR. J. Immunol. 171 (2003) 4369-4378
-
(2003)
J. Immunol.
, vol.171
, pp. 4369-4378
-
-
Atasoy, U.1
Curry, S.L.2
Lopez de Silanes, I.3
Shyu, A.B.4
Casolaro, V.5
Gorospe, M.6
Stellato, C.7
-
7
-
-
0041965736
-
Regulation of IL-11 expression in intestinal myofibroblasts: Role of c-Jun AP-1- and MAPK-dependent pathways
-
Bamba S., Andoh A., Yasui H., Makino J., Kim S., and Fujiyama Y. Regulation of IL-11 expression in intestinal myofibroblasts: Role of c-Jun AP-1- and MAPK-dependent pathways. Am. J. Physiol. Gastrointest. Liver Physiol. 285 (2003) G529-G538
-
(2003)
Am. J. Physiol. Gastrointest. Liver Physiol.
, vol.285
-
-
Bamba, S.1
Andoh, A.2
Yasui, H.3
Makino, J.4
Kim, S.5
Fujiyama, Y.6
-
8
-
-
0014193191
-
Regulation of the lac operon. Recent studies on the regulation of lactose metabolism in Escherichia coli support the operon model
-
Beckwith J.R. Regulation of the lac operon. Recent studies on the regulation of lactose metabolism in Escherichia coli support the operon model. Science 156 (1967) 597-604
-
(1967)
Science
, vol.156
, pp. 597-604
-
-
Beckwith, J.R.1
-
9
-
-
0025293278
-
Post-transcriptional regulation of granulocyte-macrophage colony-stimulating factor synthesis in murine T cells
-
Bickel M., Cohen R.B., and Pluznik D.H. Post-transcriptional regulation of granulocyte-macrophage colony-stimulating factor synthesis in murine T cells. J. Immunol. 145 (1990) 840-845
-
(1990)
J. Immunol.
, vol.145
, pp. 840-845
-
-
Bickel, M.1
Cohen, R.B.2
Pluznik, D.H.3
-
10
-
-
0042061323
-
Ajulemic acid, a nonpsychoactive cannabinoid acid, induces apoptosis in human T lymphocytes
-
Bidinger B., Torres R., Rossetti R.G., Brown L., Beltre R., Burstein S., Lian J.B., Stein G.S., and Zurier R.B. Ajulemic acid, a nonpsychoactive cannabinoid acid, induces apoptosis in human T lymphocytes. Clin. Immunol. 108 (2003) 95-102
-
(2003)
Clin. Immunol.
, vol.108
, pp. 95-102
-
-
Bidinger, B.1
Torres, R.2
Rossetti, R.G.3
Brown, L.4
Beltre, R.5
Burstein, S.6
Lian, J.B.7
Stein, G.S.8
Zurier, R.B.9
-
11
-
-
0037942875
-
Regulation of chemokine mRNA stability by lipopolysaccharide and IL-10
-
Biswas R., Datta S., Gupta J.D., Novotny M., Tebo J., and Hamilton T.A. Regulation of chemokine mRNA stability by lipopolysaccharide and IL-10. J. Immunol. 170 (2003) 6202-6208
-
(2003)
J. Immunol.
, vol.170
, pp. 6202-6208
-
-
Biswas, R.1
Datta, S.2
Gupta, J.D.3
Novotny, M.4
Tebo, J.5
Hamilton, T.A.6
-
12
-
-
0036863118
-
Tristetraprolin and other CCCH tandem zinc-finger proteins in the regulation of mRNA turnover
-
Blackshear P.J. Tristetraprolin and other CCCH tandem zinc-finger proteins in the regulation of mRNA turnover. Biochem. Soc. Trans. 30 (2002) 945-952
-
(2002)
Biochem. Soc. Trans.
, vol.30
, pp. 945-952
-
-
Blackshear, P.J.1
-
13
-
-
0038504080
-
Characteristics of the interaction of a synthetic human tristetraprolin tandem zinc finger peptide with AU-rich element-containing RNA substrates
-
Blackshear P.J., Lai W.S., Kennington E.A., Brewer G., Wilson G.M., Guan X., and Zhou P. Characteristics of the interaction of a synthetic human tristetraprolin tandem zinc finger peptide with AU-rich element-containing RNA substrates. J. Biol. Chem. 278 (2003) 19947-19955
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 19947-19955
-
-
Blackshear, P.J.1
Lai, W.S.2
Kennington, E.A.3
Brewer, G.4
Wilson, G.M.5
Guan, X.6
Zhou, P.7
-
15
-
-
0026457998
-
Contrasting mechanisms for suppression of macrophage cytokine release by transforming growth factor-beta and interleukin-10
-
Bogdan C., Paik J., Vodovotz Y., and Nathan C. Contrasting mechanisms for suppression of macrophage cytokine release by transforming growth factor-beta and interleukin-10. J. Biol. Chem. 267 (1992) 23301-23308
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 23301-23308
-
-
Bogdan, C.1
Paik, J.2
Vodovotz, Y.3
Nathan, C.4
-
16
-
-
0026337150
-
An A+U-rich element RNA-binding factor regulates c-myc stability in vitro
-
Brewer G. An A+U-rich element RNA-binding factor regulates c-myc stability in vitro. Mol. Cell. Biol. 11 (1991) 2460-2466
-
(1991)
Mol. Cell. Biol.
, vol.11
, pp. 2460-2466
-
-
Brewer, G.1
-
17
-
-
0345276462
-
The Wnt/beta-catenin->Pitx2 pathway controls the turnover of Pitx2 and other unstable mRNAs
-
Briata P., Ilengo C., Corte G., Moroni C., Rosenfeld M.G., Chen C.Y., and Gherzi R. The Wnt/beta-catenin->Pitx2 pathway controls the turnover of Pitx2 and other unstable mRNAs. Mol. Cell 12 (2003) 1201-1211
-
(2003)
Mol. Cell
, vol.12
, pp. 1201-1211
-
-
Briata, P.1
Ilengo, C.2
Corte, G.3
Moroni, C.4
Rosenfeld, M.G.5
Chen, C.Y.6
Gherzi, R.7
-
18
-
-
0034644837
-
Regulation of tumour necrosis factor alpha mRNA stability by the mitogen-activated protein kinase p38 signalling cascade
-
Brook M., Sully G., Clark A.R., and Saklatvala J. Regulation of tumour necrosis factor alpha mRNA stability by the mitogen-activated protein kinase p38 signalling cascade. FEBS Lett. 483 (2000) 57-61
-
(2000)
FEBS Lett.
, vol.483
, pp. 57-61
-
-
Brook, M.1
Sully, G.2
Clark, A.R.3
Saklatvala, J.4
-
19
-
-
0030451211
-
A cytokine mRNA-destabilizing element that is structurally and functionally distinct from A + U-rich elements
-
Brown C.Y., Lagnado C.A., and Goodall G.J. A cytokine mRNA-destabilizing element that is structurally and functionally distinct from A + U-rich elements. Proc. Natl. Acad. Sci. USA 93 (1996) 13721-13725
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 13721-13725
-
-
Brown, C.Y.1
Lagnado, C.A.2
Goodall, G.J.3
-
20
-
-
0029786910
-
Differential regulation of the stability of cytokine mRNAs in lipopolysaccharide-activated blood monocytes in response to interleukin-10
-
Brown C.Y., Lagnado C.A., Vadas M.A., and Goodall G.J. Differential regulation of the stability of cytokine mRNAs in lipopolysaccharide-activated blood monocytes in response to interleukin-10. J. Biol. Chem. 271 (1996) 20108-20112
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 20108-20112
-
-
Brown, C.Y.1
Lagnado, C.A.2
Vadas, M.A.3
Goodall, G.J.4
-
21
-
-
3242790036
-
Interleukin-1 homologues IL-1F7b and IL-18 contain functional mRNA instability elements within the coding region responsive to lipopolysaccharide
-
Bufler P., Gamboni-Robertson F., Azam T., Kim S.H., and Dinarello C.A. Interleukin-1 homologues IL-1F7b and IL-18 contain functional mRNA instability elements within the coding region responsive to lipopolysaccharide. Biochem. J. 381 (2004) 503-510
-
(2004)
Biochem. J.
, vol.381
, pp. 503-510
-
-
Bufler, P.1
Gamboni-Robertson, F.2
Azam, T.3
Kim, S.H.4
Dinarello, C.A.5
-
22
-
-
0034655161
-
Thalidomide: Current and potential clinical applications
-
Calabrese L., and Fleischer A.B. Thalidomide: Current and potential clinical applications. Am. J. Med. 108 (2000) 487-495
-
(2000)
Am. J. Med.
, vol.108
, pp. 487-495
-
-
Calabrese, L.1
Fleischer, A.B.2
-
23
-
-
2442656756
-
Immunological characterization of tristetraprolin as a low abundance, inducible, stable cytosolic protein
-
Cao H., Tuttle J.S., and Blackshear P.J. Immunological characterization of tristetraprolin as a low abundance, inducible, stable cytosolic protein. J. Biol. Chem. 279 (2004) 21489-21499
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 21489-21499
-
-
Cao, H.1
Tuttle, J.S.2
Blackshear, P.J.3
-
24
-
-
0035889956
-
Y box-binding factor promotes eosinophil survival by stabilizing granulocyte-macrophage colony-stimulating factor mRNA
-
Capowski E.E., Esnault S., Bhattacharya S., and Malter J.S. Y box-binding factor promotes eosinophil survival by stabilizing granulocyte-macrophage colony-stimulating factor mRNA. J. Immunol. 167 (2001) 5970-5976
-
(2001)
J. Immunol.
, vol.167
, pp. 5970-5976
-
-
Capowski, E.E.1
Esnault, S.2
Bhattacharya, S.3
Malter, J.S.4
-
25
-
-
0000370303
-
Identification of a common nucleotide sequence in the 3′-untranslated region of mRNA molecules specifying inflammatory mediators
-
Caput D., Beutler B., Hartog K., Thayer R., Brown-Shimer S., and Cerami A. Identification of a common nucleotide sequence in the 3′-untranslated region of mRNA molecules specifying inflammatory mediators. Proc. Natl. Acad. Sci. USA 83 (1986) 1670-1674
-
(1986)
Proc. Natl. Acad. Sci. USA
, vol.83
, pp. 1670-1674
-
-
Caput, D.1
Beutler, B.2
Hartog, K.3
Thayer, R.4
Brown-Shimer, S.5
Cerami, A.6
-
26
-
-
0035889121
-
Roles of tumor necrosis factor-alpha receptor subtypes in the pathogenesis of the tristetraprolin-deficiency syndrome
-
Carballo E., and Blackshear P.J. Roles of tumor necrosis factor-alpha receptor subtypes in the pathogenesis of the tristetraprolin-deficiency syndrome. Blood 98 (2001) 2389-2395
-
(2001)
Blood
, vol.98
, pp. 2389-2395
-
-
Carballo, E.1
Blackshear, P.J.2
-
27
-
-
0035834741
-
Decreased sensitivity of tristetraprolin-deficient cells to p38 inhibitors suggests the involvement of tristetraprolin in the p38 signaling pathway
-
Carballo E., Cao H., Lai W.S., Kennington E.A., Campbell D., and Blackshear P.J. Decreased sensitivity of tristetraprolin-deficient cells to p38 inhibitors suggests the involvement of tristetraprolin in the p38 signaling pathway. J. Biol. Chem. 276 (2001) 42580-42587
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 42580-42587
-
-
Carballo, E.1
Cao, H.2
Lai, W.S.3
Kennington, E.A.4
Campbell, D.5
Blackshear, P.J.6
-
28
-
-
0032516626
-
Feedback inhibition of macrophage tumor necrosis factor-alpha production by tristetraprolin
-
Carballo E., Lai W.S., and Blackshear P.J. Feedback inhibition of macrophage tumor necrosis factor-alpha production by tristetraprolin. Science 281 (1998) 1001-1005
-
(1998)
Science
, vol.281
, pp. 1001-1005
-
-
Carballo, E.1
Lai, W.S.2
Blackshear, P.J.3
-
29
-
-
0034653560
-
Evidence that tristetraprolin is a physiological regulator of granulocyte-macrophage colony-stimulating factor messenger RNA deadenylation and stability
-
Carballo E., Lai W.S., and Blackshear P.J. Evidence that tristetraprolin is a physiological regulator of granulocyte-macrophage colony-stimulating factor messenger RNA deadenylation and stability. Blood 95 (2000) 1891-1899
-
(2000)
Blood
, vol.95
, pp. 1891-1899
-
-
Carballo, E.1
Lai, W.S.2
Blackshear, P.J.3
-
30
-
-
0035895998
-
Protein kinase Cdelta activation by interleukin-1beta stabilizes inducible nitric-oxide synthase mRNA in pancreatic beta-cells
-
Carpenter L., Cordery D., and Biden T.J. Protein kinase Cdelta activation by interleukin-1beta stabilizes inducible nitric-oxide synthase mRNA in pancreatic beta-cells. J. Biol. Chem. 276 (2001) 5368-5374
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 5368-5374
-
-
Carpenter, L.1
Cordery, D.2
Biden, T.J.3
-
31
-
-
0028788194
-
AU-rich elements: Characterization and importance in mRNA degradation
-
Chen C.-Y.A., and Shyu A.-B. AU-rich elements: Characterization and importance in mRNA degradation. Trends Biochem. Sci. 20 (1995) 465-470
-
(1995)
Trends Biochem. Sci.
, vol.20
, pp. 465-470
-
-
Chen, C.-Y.A.1
Shyu, A.-B.2
-
32
-
-
0032546972
-
Stabilization of interleukin-2 mRNA by the c-Jun NH2-terminal kinase pathway
-
Chen C.Y., Del Gatto-Konczak F., Wu Z., and Karin M. Stabilization of interleukin-2 mRNA by the c-Jun NH2-terminal kinase pathway. Science 280 (1998) 1945-1949
-
(1998)
Science
, vol.280
, pp. 1945-1949
-
-
Chen, C.Y.1
Del Gatto-Konczak, F.2
Wu, Z.3
Karin, M.4
-
33
-
-
0034657357
-
Nucleolin and YB-1 are required for JNK-mediated interleukin-2 mRNA stabilization during T-cell activation
-
Chen C.Y., Gherzi R., Andersen J.S., Gaietta G., Jurchott K., Royer H.D., Mann M., and Karin M. Nucleolin and YB-1 are required for JNK-mediated interleukin-2 mRNA stabilization during T-cell activation. Genes Dev. 14 (2000) 1236-1248
-
(2000)
Genes Dev.
, vol.14
, pp. 1236-1248
-
-
Chen, C.Y.1
Gherzi, R.2
Andersen, J.S.3
Gaietta, G.4
Jurchott, K.5
Royer, H.D.6
Mann, M.7
Karin, M.8
-
34
-
-
18044371822
-
AU Binding Proteins Recruit the Exosome to Degrade ARE-Containing mRNAs
-
Chen C.Y., Gherzi R., Ong S.E., Chan E.L., Raijmakers R., Pruijn G.J., Stoecklin G., Moroni C., Mann M., and Karin M. AU Binding Proteins Recruit the Exosome to Degrade ARE-Containing mRNAs. Cell 107 (2001) 451-464
-
(2001)
Cell
, vol.107
, pp. 451-464
-
-
Chen, C.Y.1
Gherzi, R.2
Ong, S.E.3
Chan, E.L.4
Raijmakers, R.5
Pruijn, G.J.6
Stoecklin, G.7
Moroni, C.8
Mann, M.9
Karin, M.10
-
35
-
-
0029126879
-
mRNA decay mediated by two distinct AU-rich elements from c-fos and granulocyte-macrophage colony-stimulating factor transcripts: Different deadenylation kinetics and uncoupling from translation
-
Chen C.Y., Xu N., and Shyu A.B. mRNA decay mediated by two distinct AU-rich elements from c-fos and granulocyte-macrophage colony-stimulating factor transcripts: Different deadenylation kinetics and uncoupling from translation. Mol. Cell. Biol. 15 (1995) 5777-5788
-
(1995)
Mol. Cell. Biol.
, vol.15
, pp. 5777-5788
-
-
Chen, C.Y.1
Xu, N.2
Shyu, A.B.3
-
36
-
-
0036787920
-
Highly selective actions of HuR in antagonizing AU-rich element-mediated mRNA destabilization
-
Chen C.Y., Xu N., and Shyu A.B. Highly selective actions of HuR in antagonizing AU-rich element-mediated mRNA destabilization. Mol. Cell. Biol. 22 (2002) 7268-7278
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 7268-7278
-
-
Chen, C.Y.1
Xu, N.2
Shyu, A.B.3
-
37
-
-
1642332899
-
MAPKAP kinase 2 phosphorylates tristetraprolin on in vivo sites including Ser 178, a site required for 14-3-3 binding
-
10174-1084.
-
Chrestensen C.A., Schroeder M.J., Shabanowitz J., Hunt D.F., Pelo J.W., Worthington M.T., and Sturgill T.W. MAPKAP kinase 2 phosphorylates tristetraprolin on in vivo sites including Ser 178, a site required for 14-3-3 binding. J. Biol. Chem. 279 (2004) 10174-1084.
-
(2004)
J. Biol. Chem.
, vol.279
-
-
Chrestensen, C.A.1
Schroeder, M.J.2
Shabanowitz, J.3
Hunt, D.F.4
Pelo, J.W.5
Worthington, M.T.6
Sturgill, T.W.7
-
38
-
-
0141815718
-
The proximal region of the 3′-untranslated region of cyclooxygenase-2 is recognized by a multimeric protein complex containing HuR, TIA-1, TIAR, and the heterogeneous nuclear ribonucleoprotein U
-
Cok S.J., Acton S.J., and Morrison A.R. The proximal region of the 3′-untranslated region of cyclooxygenase-2 is recognized by a multimeric protein complex containing HuR, TIA-1, TIAR, and the heterogeneous nuclear ribonucleoprotein U. J. Biol. Chem. 278 (2003) 36157-36162
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 36157-36162
-
-
Cok, S.J.1
Acton, S.J.2
Morrison, A.R.3
-
39
-
-
0842330531
-
A multi-protein complex containing cold shock domain (Y-box) and polypyrimidine tract binding proteins forms on the vascular endothelial growth factor mRNA. Potential role in mRNA stabilization
-
Coles L.S., Bartley M.A., Bert A., Hunter J., Polyak S., Diamond P., Vadas M.A., and Goodall G.J. A multi-protein complex containing cold shock domain (Y-box) and polypyrimidine tract binding proteins forms on the vascular endothelial growth factor mRNA. Potential role in mRNA stabilization. Eur. J. Biochem. 271 (2004) 648-660
-
(2004)
Eur. J. Biochem.
, vol.271
, pp. 648-660
-
-
Coles, L.S.1
Bartley, M.A.2
Bert, A.3
Hunter, J.4
Polyak, S.5
Diamond, P.6
Vadas, M.A.7
Goodall, G.J.8
-
40
-
-
0034851864
-
Blockade of collagen-induced arthritis post-onset by antibody to granulocyte-macrophage colony-stimulating factor (GM-CSF): Requirement for GM-CSF in the effector phase of disease
-
Cook A.D., Braine E.L., Campbell I.K., Rich M.J., and Hamilton J.A. Blockade of collagen-induced arthritis post-onset by antibody to granulocyte-macrophage colony-stimulating factor (GM-CSF): Requirement for GM-CSF in the effector phase of disease. Arthritis Res. 3 (2001) 293-298
-
(2001)
Arthritis Res.
, vol.3
, pp. 293-298
-
-
Cook, A.D.1
Braine, E.L.2
Campbell, I.K.3
Rich, M.J.4
Hamilton, J.A.5
-
41
-
-
2442566370
-
Cytoplasmic foci are sites of mRNA decay in human cells
-
Cougot N., Babajko S., and Seraphin B. Cytoplasmic foci are sites of mRNA decay in human cells. J. Cell Biol. 165 (2004) 31-40
-
(2004)
J. Cell Biol.
, vol.165
, pp. 31-40
-
-
Cougot, N.1
Babajko, S.2
Seraphin, B.3
-
43
-
-
0032901194
-
Sustained elevated levels of VCAM-1 in cultured fibroblast-like synoviocytes can be achieved by TNF-alpha in combination with either IL-4 or IL-13 through increased mRNA stability
-
Croft D., McIntyre P., Wibulswas A., and Kramer I. Sustained elevated levels of VCAM-1 in cultured fibroblast-like synoviocytes can be achieved by TNF-alpha in combination with either IL-4 or IL-13 through increased mRNA stability. Am. J. Pathol. 154 (1999) 1149-1158
-
(1999)
Am. J. Pathol.
, vol.154
, pp. 1149-1158
-
-
Croft, D.1
McIntyre, P.2
Wibulswas, A.3
Kramer, I.4
-
44
-
-
0035900649
-
Fragile X mental retardation protein targets G quartet mRNAs important for neuronal function
-
Darnell J.C., Jensen K.B., Jin P., Brown V., Warren S.T., and Darnell R.B. Fragile X mental retardation protein targets G quartet mRNAs important for neuronal function. Cell 107 (2001) 489-499
-
(2001)
Cell
, vol.107
, pp. 489-499
-
-
Darnell, J.C.1
Jensen, K.B.2
Jin, P.3
Brown, V.4
Warren, S.T.5
Darnell, R.B.6
-
45
-
-
1642264316
-
The fragile X mental retardation protein, FMRP, recognizes G-quartets
-
Darnell J.C., Warren S.T., and Darnell R.B. The fragile X mental retardation protein, FMRP, recognizes G-quartets. Ment. Retard. Dev. Disabil. Res. Rev. 10 (2004) 49-52
-
(2004)
Ment. Retard. Dev. Disabil. Res. Rev.
, vol.10
, pp. 49-52
-
-
Darnell, J.C.1
Warren, S.T.2
Darnell, R.B.3
-
46
-
-
0032951716
-
p38 mitogen-activated protein kinase regulates cyclooxygenase-2 mRNA stability and transcription in lipopolysaccharide-treated human monocytes
-
Dean J.L., Brook M., Clark A.R., and Saklatvala J. p38 mitogen-activated protein kinase regulates cyclooxygenase-2 mRNA stability and transcription in lipopolysaccharide-treated human monocytes. J. Biol. Chem. 274 (1999) 264-269
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 264-269
-
-
Dean, J.L.1
Brook, M.2
Clark, A.R.3
Saklatvala, J.4
-
47
-
-
0037106453
-
Identification of a novel AU-rich-element-binding protein which is related to AUF1
-
Dean J.L., Sully G., Wait R., Rawlinson L., Clark A.R., and Saklatvala J. Identification of a novel AU-rich-element-binding protein which is related to AUF1. Biochem. J. 366 (2002) 709-719
-
(2002)
Biochem. J.
, vol.366
, pp. 709-719
-
-
Dean, J.L.1
Sully, G.2
Wait, R.3
Rawlinson, L.4
Clark, A.R.5
Saklatvala, J.6
-
48
-
-
0037093989
-
Evidence for a dual mechanism for IL-10 suppression of TNF-alpha production that does not involve inhibition of p38 mitogen-activated protein kinase or NF-kappa B in primary human macrophages
-
Denys A., Udalova I.A., Smith C., Williams L.M., Ciesielski C.J., Campbell J., Andrews C., Kwaitkowski D., and Foxwell B.M. Evidence for a dual mechanism for IL-10 suppression of TNF-alpha production that does not involve inhibition of p38 mitogen-activated protein kinase or NF-kappa B in primary human macrophages. J. Immunol. 168 (2002) 4837-4845
-
(2002)
J. Immunol.
, vol.168
, pp. 4837-4845
-
-
Denys, A.1
Udalova, I.A.2
Smith, C.3
Williams, L.M.4
Ciesielski, C.J.5
Campbell, J.6
Andrews, C.7
Kwaitkowski, D.8
Foxwell, B.M.9
-
49
-
-
0037154965
-
Gene-specific regulation by general translation factors
-
Dever T.E. Gene-specific regulation by general translation factors. Cell 108 (2002) 545-556
-
(2002)
Cell
, vol.108
, pp. 545-556
-
-
Dever, T.E.1
-
50
-
-
0032941747
-
Hypoxic regulation of vascular endothelial growth factor mRNA stability requires the cooperation of multiple RNA elements
-
Dibbens J.A., Miller D.L., Damert A., Risau W., Vadas M.A., and Goodall G.J. Hypoxic regulation of vascular endothelial growth factor mRNA stability requires the cooperation of multiple RNA elements. Mol. Biol. Cell 10 (1999) 907-919
-
(1999)
Mol. Biol. Cell
, vol.10
, pp. 907-919
-
-
Dibbens, J.A.1
Miller, D.L.2
Damert, A.3
Risau, W.4
Vadas, M.A.5
Goodall, G.J.6
-
51
-
-
22544452988
-
NF-κ B-mediated MyoD decay during muscle wasting requires nitric oxide synthase mRNA stabilization, HuR protein, and nitric oxide release
-
Di Marco S., Mazroui R., Dallaire P., Chittur S., Tenenbaum S.A., Radzioch D., Marette A., and Gallouzi I.E. NF-κ B-mediated MyoD decay during muscle wasting requires nitric oxide synthase mRNA stabilization, HuR protein, and nitric oxide release. Mol. Cell. Biol. 25 (2005) 6533-6545
-
(2005)
Mol. Cell. Biol.
, vol.25
, pp. 6533-6545
-
-
Di Marco, S.1
Mazroui, R.2
Dallaire, P.3
Chittur, S.4
Tenenbaum, S.A.5
Radzioch, D.6
Marette, A.7
Gallouzi, I.E.8
-
52
-
-
0041622806
-
Regulation of cyclooxygenase-2 expression by the translational silencer TIA-1
-
Dixon D.A., Balch G.C., Kedersha N., Anderson P., Zimmerman G.A., Beauchamp R.D., and Prescott S.M. Regulation of cyclooxygenase-2 expression by the translational silencer TIA-1. J. Exp. Med. 198 (2003) 475-481
-
(2003)
J. Exp. Med.
, vol.198
, pp. 475-481
-
-
Dixon, D.A.1
Balch, G.C.2
Kedersha, N.3
Anderson, P.4
Zimmerman, G.A.5
Beauchamp, R.D.6
Prescott, S.M.7
-
53
-
-
0030737716
-
Seeing the wood for the trees: The forgotten role of neutrophils in rheumatoid arthritis
-
Edwards S., and Hallett M. Seeing the wood for the trees: The forgotten role of neutrophils in rheumatoid arthritis. Immunol. Today 18 (1997) 320-324
-
(1997)
Immunol. Today
, vol.18
, pp. 320-324
-
-
Edwards, S.1
Hallett, M.2
-
54
-
-
0033571755
-
Primary peripheral blood eosinophils rapidly degrade transfected granulocyte-macrophage colony-stimulating factor mRNA
-
Esnault S., and Malter J.S. Primary peripheral blood eosinophils rapidly degrade transfected granulocyte-macrophage colony-stimulating factor mRNA. J. Immunol. 163 (1999) 5228-5234
-
(1999)
J. Immunol.
, vol.163
, pp. 5228-5234
-
-
Esnault, S.1
Malter, J.S.2
-
55
-
-
0032526427
-
Overexpression of HuR, a nuclear-cytoplasmic shuttling protein, increases the in vivo stability of ARE-containing mRNAs
-
Fan X.C., and Steitz J.A. Overexpression of HuR, a nuclear-cytoplasmic shuttling protein, increases the in vivo stability of ARE-containing mRNAs. EMBO J. 17 (1998) 3448-3460
-
(1998)
EMBO J.
, vol.17
, pp. 3448-3460
-
-
Fan, X.C.1
Steitz, J.A.2
-
56
-
-
0023904804
-
Human pro-IL-1 beta gene expression in monocytic cells is regulated by two distinct pathways
-
Fenton M.J., Vermeulen M.W., Clark B.D., Webb A.C., and Auron P.E. Human pro-IL-1 beta gene expression in monocytic cells is regulated by two distinct pathways. J. Immunol. 140 (1988) 2267-2273
-
(1988)
J. Immunol.
, vol.140
, pp. 2267-2273
-
-
Fenton, M.J.1
Vermeulen, M.W.2
Clark, B.D.3
Webb, A.C.4
Auron, P.E.5
-
57
-
-
19344362627
-
RNA decapping inside and outside of processing bodies
-
Fillman C., and Lykke-Andersen J. RNA decapping inside and outside of processing bodies. Curr. Opin. Cell Biol. 17 (2005) 326-331
-
(2005)
Curr. Opin. Cell Biol.
, vol.17
, pp. 326-331
-
-
Fillman, C.1
Lykke-Andersen, J.2
-
58
-
-
0033555659
-
ELAV proteins stabilize deadenylated intermediates in a novel in vitro mRNA deadenylation/degradation system
-
Ford L.P., Watson J., Keene J.D., and Wilusz J. ELAV proteins stabilize deadenylated intermediates in a novel in vitro mRNA deadenylation/degradation system. Genes Dev. 13 (1999) 188-201
-
(1999)
Genes Dev.
, vol.13
, pp. 188-201
-
-
Ford, L.P.1
Watson, J.2
Keene, J.D.3
Wilusz, J.4
-
59
-
-
0035282971
-
A novel mRNA-decapping activity in HeLa cytoplasmic extracts is regulated by AU-rich elements
-
Gao M., Wilusz C.J., Peltz S.W., and Wilusz J. A novel mRNA-decapping activity in HeLa cytoplasmic extracts is regulated by AU-rich elements. EMBO J. 20 (2001) 1134-1143
-
(2001)
EMBO J.
, vol.20
, pp. 1134-1143
-
-
Gao, M.1
Wilusz, C.J.2
Peltz, S.W.3
Wilusz, J.4
-
60
-
-
14044275840
-
Fragile X-related protein FXR1P regulates proinflammatory cytokine tumor necrosis factor expression at the post-transcriptional level
-
Garnon J., Lachance C., Di Marco S., Hel Z., Marion D., Ruiz M.C., Newkirk M.M., Khandjian E.W., and Radzioch D. Fragile X-related protein FXR1P regulates proinflammatory cytokine tumor necrosis factor expression at the post-transcriptional level. J. Biol. Chem. 280 (2005) 5750-5763
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 5750-5763
-
-
Garnon, J.1
Lachance, C.2
Di Marco, S.3
Hel, Z.4
Marion, D.5
Ruiz, M.C.6
Newkirk, M.M.7
Khandjian, E.W.8
Radzioch, D.9
-
61
-
-
19344365947
-
Extensive association of functionally and cytotopically related mRNAs with Puf family RNA-binding proteins in yeast
-
Gerber A.P., Herschlag D., and Brown P.O. Extensive association of functionally and cytotopically related mRNAs with Puf family RNA-binding proteins in yeast. PLoS Biol. 2 (2004) E79
-
(2004)
PLoS Biol.
, vol.2
-
-
Gerber, A.P.1
Herschlag, D.2
Brown, P.O.3
-
62
-
-
2942612333
-
A KH domain RNA binding protein, KSRP, promotes ARE-directed mRNA turnover by recruiting the degradation machinery
-
Gherzi R., Lee K.Y., Briata P., Wegmuller D., Moroni C., Karin M., and Chen C.Y. A KH domain RNA binding protein, KSRP, promotes ARE-directed mRNA turnover by recruiting the degradation machinery. Mol. Cell 14 (2004) 571-583
-
(2004)
Mol. Cell
, vol.14
, pp. 571-583
-
-
Gherzi, R.1
Lee, K.Y.2
Briata, P.3
Wegmuller, D.4
Moroni, C.5
Karin, M.6
Chen, C.Y.7
-
63
-
-
1842778846
-
In vivo studies of translational repression mediated by the granulocyte-macrophage colony-stimulating factor AU-rich element
-
Grosset C., Boniface R., Duchez P., Solanilla A., Cosson B., and Ripoche J. In vivo studies of translational repression mediated by the granulocyte-macrophage colony-stimulating factor AU-rich element. J. Biol. Chem. 279 (2004) 13354-13362
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 13354-13362
-
-
Grosset, C.1
Boniface, R.2
Duchez, P.3
Solanilla, A.4
Cosson, B.5
Ripoche, J.6
-
64
-
-
0036679853
-
GM-CSF in inflammation and autoimmunity
-
Hamilton J.A. GM-CSF in inflammation and autoimmunity. Trends Immunol. 23 (2002) 403-408
-
(2002)
Trends Immunol.
, vol.23
, pp. 403-408
-
-
Hamilton, J.A.1
-
65
-
-
0025098538
-
Endotoxin-responsive sequences control cachectin/tumor necrosis factor biosynthesis at the translational level
-
Han J., Brown T., and Beutler B. Endotoxin-responsive sequences control cachectin/tumor necrosis factor biosynthesis at the translational level. J. Exp. Med. 171 (1990) 465-475
-
(1990)
J. Exp. Med.
, vol.171
, pp. 465-475
-
-
Han, J.1
Brown, T.2
Beutler, B.3
-
66
-
-
0033634654
-
Regulated translation initiation controls stress-induced gene expression in mammalian cells
-
Harding H., Novoa Y., Zhang H., Zeng R., Wek M., Schapira M., and Ron D. Regulated translation initiation controls stress-induced gene expression in mammalian cells. Mol. Cell 6 (2000) 1099-1108
-
(2000)
Mol. Cell
, vol.6
, pp. 1099-1108
-
-
Harding, H.1
Novoa, Y.2
Zhang, H.3
Zeng, R.4
Wek, M.5
Schapira, M.6
Ron, D.7
-
67
-
-
0033634641
-
Perk is essential for translational regulation and cell survival during the unfolded protein response
-
Harding H.P., Zhang Y., Bertolotti A., Zeng H., and Ron D. Perk is essential for translational regulation and cell survival during the unfolded protein response. Mol. Cell 5 (2000) 897-904
-
(2000)
Mol. Cell
, vol.5
, pp. 897-904
-
-
Harding, H.P.1
Zhang, Y.2
Bertolotti, A.3
Zeng, H.4
Ron, D.5
-
68
-
-
0036183618
-
Regulation of nuclear gamma interferon gene expression by interleukin 12 (IL-12) and IL-2 represents a novel form of posttranscriptional control
-
Hodge D.L., Martinez A., Julias J.G., Taylor L.S., and Young H.A. Regulation of nuclear gamma interferon gene expression by interleukin 12 (IL-12) and IL-2 represents a novel form of posttranscriptional control. Mol. Cell. Biol. 22 (2002) 1742-1753
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 1742-1753
-
-
Hodge, D.L.1
Martinez, A.2
Julias, J.G.3
Taylor, L.S.4
Young, H.A.5
-
69
-
-
0032823313
-
Induction of interleukin-8 synthesis integrates effects on transcription and mRNA degradation from at least three different cytokine- or stress-activated signal transduction pathways
-
Holtmann H., Winzen R., Holland P., Eickemeier S., Hoffmann E., Wallach D., Malinin N.L., Cooper J.A., Resch K., and Kracht M. Induction of interleukin-8 synthesis integrates effects on transcription and mRNA degradation from at least three different cytokine- or stress-activated signal transduction pathways. Mol. Cell. Biol. 19 (1999) 6742-6753
-
(1999)
Mol. Cell. Biol.
, vol.19
, pp. 6742-6753
-
-
Holtmann, H.1
Winzen, R.2
Holland, P.3
Eickemeier, S.4
Hoffmann, E.5
Wallach, D.6
Malinin, N.L.7
Cooper, J.A.8
Resch, K.9
Kracht, M.10
-
70
-
-
0035469811
-
Regulated control by granulocyte-macrophage colony-stimulating factor AU-rich element during mouse embryogenesis
-
Houzet L., Morello D., Defrance P., Mercier P., Huez G., and Kruys V. Regulated control by granulocyte-macrophage colony-stimulating factor AU-rich element during mouse embryogenesis. Blood 98 (2001) 1281-1288
-
(2001)
Blood
, vol.98
, pp. 1281-1288
-
-
Houzet, L.1
Morello, D.2
Defrance, P.3
Mercier, P.4
Huez, G.5
Kruys, V.6
-
72
-
-
0347064348
-
ATP potentiates interleukin-1 beta-induced MMP-9 expression in mesangial cells via recruitment of the ELAV protein HuR
-
Huwiler A., Akool el S., Aschrafi A., Hamada F.M., Pfeilschifter J., and Eberhardt W. ATP potentiates interleukin-1 beta-induced MMP-9 expression in mesangial cells via recruitment of the ELAV protein HuR. J. Biol. Chem. 278 (2003) 51758-51769
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 51758-51769
-
-
Huwiler, A.1
Akool el, S.2
Aschrafi, A.3
Hamada, F.M.4
Pfeilschifter, J.5
Eberhardt, W.6
-
73
-
-
0028861841
-
Regulation of vascular cell adhesion molecule-1 expression by IL-4 and TNF-alpha in cultured endothelial cells
-
Iademarco M.F., Barks J.L., and Dean D.C. Regulation of vascular cell adhesion molecule-1 expression by IL-4 and TNF-alpha in cultured endothelial cells. J. Clin. Invest. 95 (1995) 264-271
-
(1995)
J. Clin. Invest.
, vol.95
, pp. 264-271
-
-
Iademarco, M.F.1
Barks, J.L.2
Dean, D.C.3
-
74
-
-
0029117223
-
Hypoxia-induced transcriptional activation and increased mRNA stability of vascular endothelial growth factor in C6 glioma cells
-
Ikeda E., Achen M.G., Breier G., and Risau W. Hypoxia-induced transcriptional activation and increased mRNA stability of vascular endothelial growth factor in C6 glioma cells. J. Biol. Chem. 270 (1995) 19761-19766
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 19761-19766
-
-
Ikeda, E.1
Achen, M.G.2
Breier, G.3
Risau, W.4
-
75
-
-
0036909093
-
The human LSm1-7 proteins colocalize with the mRNA-degrading enzymes Dcp1/2 and Xrnl in distinct cytoplasmic foci
-
Ingelfinger D., Arndt-Jovin D.J., Luhrmann R., and Achsel T. The human LSm1-7 proteins colocalize with the mRNA-degrading enzymes Dcp1/2 and Xrnl in distinct cytoplasmic foci. RNA 8 (2002) 1489-1501
-
(2002)
RNA
, vol.8
, pp. 1489-1501
-
-
Ingelfinger, D.1
Arndt-Jovin, D.J.2
Luhrmann, R.3
Achsel, T.4
-
76
-
-
20044388720
-
Involvement of microRNA in AU-rich element-mediated mRNA instability
-
Jing Q., Huang S., Guth S., Zarubin T., Motoyama A., Chen J., Di Padova F., Lin S.C., Gram H., and Han J. Involvement of microRNA in AU-rich element-mediated mRNA instability. Cell 120 (2005) 623-634
-
(2005)
Cell
, vol.120
, pp. 623-634
-
-
Jing, Q.1
Huang, S.2
Guth, S.3
Zarubin, T.4
Motoyama, A.5
Chen, J.6
Di Padova, F.7
Lin, S.C.8
Gram, H.9
Han, J.10
-
77
-
-
0037142608
-
Multiple tristetraprolin sequence domains required to induce apoptosis and modulate responses to TNFalpha through distinct pathways
-
Johnson B.A., and Blackwell T.K. Multiple tristetraprolin sequence domains required to induce apoptosis and modulate responses to TNFalpha through distinct pathways. Oncogene 21 (2002) 4237-4246
-
(2002)
Oncogene
, vol.21
, pp. 4237-4246
-
-
Johnson, B.A.1
Blackwell, T.K.2
-
78
-
-
0034704847
-
Similar but distinct effects of the tristetraprolin/TIS11 immediate-early proteins on cell survival
-
Johnson B.A., Geha M., and Blackwell T.K. Similar but distinct effects of the tristetraprolin/TIS11 immediate-early proteins on cell survival. Oncogene 19 (2000) 1657-1664
-
(2000)
Oncogene
, vol.19
, pp. 1657-1664
-
-
Johnson, B.A.1
Geha, M.2
Blackwell, T.K.3
-
79
-
-
0037124067
-
Cytoplasmic localization of Tristetraprolin involves 14-3-3-dependent and -independent mechanisms
-
Johnson B.A., Stehn J.R., Yaffe M.B., and Blackwell T.K. Cytoplasmic localization of Tristetraprolin involves 14-3-3-dependent and -independent mechanisms. J. Biol. Chem. 277 (2002) 18029-18036
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 18029-18036
-
-
Johnson, B.A.1
Stehn, J.R.2
Yaffe, M.B.3
Blackwell, T.K.4
-
80
-
-
20944443597
-
Inflammatory arthritis requires Foxo3a to prevent Fas ligand-induced neutrophil apoptosis
-
Jonsson H., Allen P., and Peng S.L. Inflammatory arthritis requires Foxo3a to prevent Fas ligand-induced neutrophil apoptosis. Nat. Med. 11 (2005) 666-671
-
(2005)
Nat. Med.
, vol.11
, pp. 666-671
-
-
Jonsson, H.1
Allen, P.2
Peng, S.L.3
-
81
-
-
0030267257
-
Induction of rapid IL-1 beta mRNA degradation in THP-1 cells mediated through the AU-rich region in the 3′UTR by a radicicol analogue
-
Kastelic T., Schnyder J., Leutwiler A., Traber R., Streit B., Niggli H., Mac Kenzie A., and Cheneval D. Induction of rapid IL-1 beta mRNA degradation in THP-1 cells mediated through the AU-rich region in the 3′UTR by a radicicol analogue. Cytokine 8 (1996) 751-761
-
(1996)
Cytokine
, vol.8
, pp. 751-761
-
-
Kastelic, T.1
Schnyder, J.2
Leutwiler, A.3
Traber, R.4
Streit, B.5
Niggli, H.6
Mac Kenzie, A.7
Cheneval, D.8
-
82
-
-
0036569806
-
Molecular phenotype of Fragile X syndrome: FMRP, FXRPs, and protein targets
-
Kaufmann W.E., Cohen S., Sun H.T., and Ho G. Molecular phenotype of Fragile X syndrome: FMRP, FXRPs, and protein targets. Microsc. Res. Tech. 57 (2002) 135-144
-
(2002)
Microsc. Res. Tech.
, vol.57
, pp. 135-144
-
-
Kaufmann, W.E.1
Cohen, S.2
Sun, H.T.3
Ho, G.4
-
83
-
-
0036863320
-
Stress granules: Sites of mRNA triage that regulate mRNA stability and translatability
-
Kedersha N., and Anderson P. Stress granules: Sites of mRNA triage that regulate mRNA stability and translatability. Biochem. Soc. Trans 30 (2001) 963-969
-
(2001)
Biochem. Soc. Trans
, vol.30
, pp. 963-969
-
-
Kedersha, N.1
Anderson, P.2
-
84
-
-
0036154218
-
Evidence that ternary complex (eIF2-GTP-tRNA(i)(Met))-deficient preinitiation complexes are core constituents of mammalian stress granules
-
Kedersha N., Chen S., Gilks N., Li W., Miller I.J., Stahl J., and Anderson P. Evidence that ternary complex (eIF2-GTP-tRNA(i)(Met))-deficient preinitiation complexes are core constituents of mammalian stress granules. Mol. Biol. Cell 13 (2002) 195-210
-
(2002)
Mol. Biol. Cell
, vol.13
, pp. 195-210
-
-
Kedersha, N.1
Chen, S.2
Gilks, N.3
Li, W.4
Miller, I.J.5
Stahl, J.6
Anderson, P.7
-
85
-
-
0034638837
-
Dynamic shuttling of TIA-1 accompanies the recruitment of mRNA to mammalian stress granules
-
Kedersha N., Cho M.R., Li W., Yacono P.W., Chen S., Gilks N., Golan D.E., and Anderson P. Dynamic shuttling of TIA-1 accompanies the recruitment of mRNA to mammalian stress granules. J. Cell Biol. 151 (2000) 1257-1268
-
(2000)
J. Cell Biol.
, vol.151
, pp. 1257-1268
-
-
Kedersha, N.1
Cho, M.R.2
Li, W.3
Yacono, P.W.4
Chen, S.5
Gilks, N.6
Golan, D.E.7
Anderson, P.8
-
86
-
-
0033611157
-
RNA-binding proteins TIA-1 and TIAR link the phosphorylation of eIF-2 alpha to the assembly of mammalian stress granules
-
Kedersha N.L., Gupta M., Li W., Miller I., and Anderson P. RNA-binding proteins TIA-1 and TIAR link the phosphorylation of eIF-2 alpha to the assembly of mammalian stress granules. J. Cell Biol. 147 (1999) 1431-1442
-
(1999)
J. Cell Biol.
, vol.147
, pp. 1431-1442
-
-
Kedersha, N.L.1
Gupta, M.2
Li, W.3
Miller, I.4
Anderson, P.5
-
87
-
-
22344455246
-
Stress granules and processing bodies are dynamically linked sites of mRNP remodeling
-
Kedersha N., Stoecklin G., Ayodele M., Yacono P., Lykke-Andersen J., Fitzler M.J., Scheuner D., Kaufman R.J., Golan D.E., and Andersen P. Stress granules and processing bodies are dynamically linked sites of mRNP remodeling. J. Cell Biol. 169 (2005) 871-884
-
(2005)
J. Cell Biol.
, vol.169
, pp. 871-884
-
-
Kedersha, N.1
Stoecklin, G.2
Ayodele, M.3
Yacono, P.4
Lykke-Andersen, J.5
Fitzler, M.J.6
Scheuner, D.7
Kaufman, R.J.8
Golan, D.E.9
Andersen, P.10
-
88
-
-
0036289532
-
Eukaryotic mRNPs may represent posttranscriptional operons
-
Keene J.D., and Tenenbaum S.A. Eukaryotic mRNPs may represent posttranscriptional operons. Mol. Cell 9 (2002) 1161-1167
-
(2002)
Mol. Cell
, vol.9
, pp. 1161-1167
-
-
Keene, J.D.1
Tenenbaum, S.A.2
-
89
-
-
0026039673
-
Transgenic mice expressing human tumour necrosis factor: A predictive genetic model of arthritis
-
Keffer J., Probert L., Cazlaris H., Georgopoulos S., Kaslaris E., Kioussis D., and Kollias G. Transgenic mice expressing human tumour necrosis factor: A predictive genetic model of arthritis. EMBO J. 10 (1991) 4025-4031
-
(1991)
EMBO J.
, vol.10
, pp. 4025-4031
-
-
Keffer, J.1
Probert, L.2
Cazlaris, H.3
Georgopoulos, S.4
Kaslaris, E.5
Kioussis, D.6
Kollias, G.7
-
90
-
-
0141957295
-
Chemically modified tetracyclines selectively inhibit IL-6 expression in osteoblasts by decreasing mRNA stability
-
Kirkwood K., Martin T., Andreadis S.T., and Kim Y.J. Chemically modified tetracyclines selectively inhibit IL-6 expression in osteoblasts by decreasing mRNA stability. Biochem. Pharmacol. 66 (2003) 1809-1819
-
(2003)
Biochem. Pharmacol.
, vol.66
, pp. 1809-1819
-
-
Kirkwood, K.1
Martin, T.2
Andreadis, S.T.3
Kim, Y.J.4
-
91
-
-
0033104734
-
Cutting edge: Clustered AU-rich elements are the target of IL-10-mediated mRNA destabilization in mouse macrophages
-
Kishore R., Tebo J.M., Kolosov M., and Hamilton T.A. Cutting edge: Clustered AU-rich elements are the target of IL-10-mediated mRNA destabilization in mouse macrophages. J. Immunol. 162 (1999) 2457-2461
-
(1999)
J. Immunol.
, vol.162
, pp. 2457-2461
-
-
Kishore, R.1
Tebo, J.M.2
Kolosov, M.3
Hamilton, T.A.4
-
92
-
-
0023812166
-
Transcriptional and posttranscriptional modulation of myeloid colony-stimulating factor expression by tumor necrosis factor and other agents
-
Koeffler H.P., Gasson J., and Tobler A. Transcriptional and posttranscriptional modulation of myeloid colony-stimulating factor expression by tumor necrosis factor and other agents. Mol. Cell. Biol. 8 (1988) 3432-3438
-
(1988)
Mol. Cell. Biol.
, vol.8
, pp. 3432-3438
-
-
Koeffler, H.P.1
Gasson, J.2
Tobler, A.3
-
93
-
-
9944233058
-
Nitric oxide in inflammatory bowel disease: A universal messenger in an unsolved puzzle
-
Kolios G., Valatas V., and Ward S.G. Nitric oxide in inflammatory bowel disease: A universal messenger in an unsolved puzzle. Immunology 113 (2004) 427-437
-
(2004)
Immunology
, vol.113
, pp. 427-437
-
-
Kolios, G.1
Valatas, V.2
Ward, S.G.3
-
94
-
-
16644384082
-
Modeling the function of tumor necrosis factor in immune pathophysiology
-
Kollias G. Modeling the function of tumor necrosis factor in immune pathophysiology. Autoimmun. Rev. 3 Suppl. 1 (2004) S24-S25
-
(2004)
Autoimmun. Rev.
, vol.3
, Issue.SUPPL. 1
-
-
Kollias, G.1
-
95
-
-
0037121941
-
Genetic dissection of the cellular pathways and signaling mechanisms in modeled tumor necrosis factor-induced Crohn's-like inflammatory bowel disease
-
Kontoyiannis D., Boulougouris G., Manoloukos M., Armaka M., Apostolaki M., Pizarro T., Kotlyarov A., Forster I., Flavell R., Gaestel M., Tsichlis P., Cominelli F., and Kollias G. Genetic dissection of the cellular pathways and signaling mechanisms in modeled tumor necrosis factor-induced Crohn's-like inflammatory bowel disease. J. Exp. Med. 196 (2002) 1563-1574
-
(2002)
J. Exp. Med.
, vol.196
, pp. 1563-1574
-
-
Kontoyiannis, D.1
Boulougouris, G.2
Manoloukos, M.3
Armaka, M.4
Apostolaki, M.5
Pizarro, T.6
Kotlyarov, A.7
Forster, I.8
Flavell, R.9
Gaestel, M.10
Tsichlis, P.11
Cominelli, F.12
Kollias, G.13
-
96
-
-
0035898647
-
Interleukin-10 targets p38 MAPK to modulate ARE-dependent TNF mRNA translation and limit intestinal pathology
-
Kontoyiannis D., Kotlyarov A., Carballo E., Alexopoulou L., Blackshear P.J., Gaestel M., Davis R., Flavell R., and Kollias G. Interleukin-10 targets p38 MAPK to modulate ARE-dependent TNF mRNA translation and limit intestinal pathology. EMBO J. 20 (2001) 3760-3770
-
(2001)
EMBO J.
, vol.20
, pp. 3760-3770
-
-
Kontoyiannis, D.1
Kotlyarov, A.2
Carballo, E.3
Alexopoulou, L.4
Blackshear, P.J.5
Gaestel, M.6
Davis, R.7
Flavell, R.8
Kollias, G.9
-
97
-
-
0033103805
-
Impaired on/off regulation of TNF biosynthesis in mice lacking TNF AU-rich elements: Implications for joint and gut-associated immunopathologies
-
Kontoyiannis D., Pasparakis M., Pizarro T.T., Cominelli F., and Kollias G. Impaired on/off regulation of TNF biosynthesis in mice lacking TNF AU-rich elements: Implications for joint and gut-associated immunopathologies. Immunity 10 (1999) 387-398
-
(1999)
Immunity
, vol.10
, pp. 387-398
-
-
Kontoyiannis, D.1
Pasparakis, M.2
Pizarro, T.T.3
Cominelli, F.4
Kollias, G.5
-
98
-
-
0032790226
-
Collagenase-3 (MMP-13) and its activators in rheumatoid arthritis: Localization in the pannus-hard tissue junction and inhibition by alendronate
-
Konttinen Y.T., Salo T., Hanemaaijer R., Valleala H., Sorsa T., Sutinen M., Ceponis A., Xu J.W., Santavirta S., Teronen O., and Lopez-Otin C. Collagenase-3 (MMP-13) and its activators in rheumatoid arthritis: Localization in the pannus-hard tissue junction and inhibition by alendronate. Matrix Biol. 18 (1999) 401-412
-
(1999)
Matrix Biol.
, vol.18
, pp. 401-412
-
-
Konttinen, Y.T.1
Salo, T.2
Hanemaaijer, R.3
Valleala, H.4
Sorsa, T.5
Sutinen, M.6
Ceponis, A.7
Xu, J.W.8
Santavirta, S.9
Teronen, O.10
Lopez-Otin, C.11
-
99
-
-
0033145354
-
MAPKAP kinase 2 is essential for LPS-induced TNF-alpha biosynthesis
-
Kotlyarov A., Neininger A., Schubert C., Eckert R., Birchmeier C., Volk H.D., and Gaestel M. MAPKAP kinase 2 is essential for LPS-induced TNF-alpha biosynthesis. Nat. Cell Biol. 1 (1999) 94-97
-
(1999)
Nat. Cell Biol.
, vol.1
, pp. 94-97
-
-
Kotlyarov, A.1
Neininger, A.2
Schubert, C.3
Eckert, R.4
Birchmeier, C.5
Volk, H.D.6
Gaestel, M.7
-
100
-
-
0034960171
-
Tight binding of the phosphorylated alpha subunit of initiation factor 2 (eIF2alpha) to the regulatory subunits of guanine nucleotide exchange factor eIF2B is required for inhibition of translation initiation
-
Krishnamoorthy T., Pavitt G.D., Zhang F., Dever T.E., and Hinnebusch A.G. Tight binding of the phosphorylated alpha subunit of initiation factor 2 (eIF2alpha) to the regulatory subunits of guanine nucleotide exchange factor eIF2B is required for inhibition of translation initiation. Mol. Cell. Biol. 21 (2001) 5018-5030
-
(2001)
Mol. Cell. Biol.
, vol.21
, pp. 5018-5030
-
-
Krishnamoorthy, T.1
Pavitt, G.D.2
Zhang, F.3
Dever, T.E.4
Hinnebusch, A.G.5
-
101
-
-
0036669583
-
Mammalian arachidonate 15-lipoxygenases structure, function, and biological implications
-
Kuhn H., Walther M., and Kuban R.J. Mammalian arachidonate 15-lipoxygenases structure, function, and biological implications. Prostaglandins Other Lipid Mediat. 68-69 (2002) 263-290
-
(2002)
Prostaglandins Other Lipid Mediat.
, vol.68-69
, pp. 263-290
-
-
Kuhn, H.1
Walther, M.2
Kuban, R.J.3
-
102
-
-
0036894711
-
ELAV/Hu proteins inhibit p27 translation via an IRES element in the p27 5′UTR
-
Kullmann M., Gopfert U., Siewe B., and Hengst L. ELAV/Hu proteins inhibit p27 translation via an IRES element in the p27 5′UTR. Genes Dev. 16 (2002) 3087-3099
-
(2002)
Genes Dev.
, vol.16
, pp. 3087-3099
-
-
Kullmann, M.1
Gopfert, U.2
Siewe, B.3
Hengst, L.4
-
103
-
-
0028089754
-
AUUUA is not sufficient to promote poly(A) shortening and degradation of an mRNA: The functional sequence within AU-rich elements may be UUAUUUA(U/A)(U/A)
-
Lagnado C.A., Brown C.Y., and Goodall G.J. AUUUA is not sufficient to promote poly(A) shortening and degradation of an mRNA: The functional sequence within AU-rich elements may be UUAUUUA(U/A)(U/A). Mol. Cell. Biol. 14 (1994) 7984-7995
-
(1994)
Mol. Cell. Biol.
, vol.14
, pp. 7984-7995
-
-
Lagnado, C.A.1
Brown, C.Y.2
Goodall, G.J.3
-
104
-
-
0042844654
-
c-Jun NH2-terminal kinase inhibitor anthra(1,9-cd)pyrazol-6(2H)-one reduces inducible nitric-oxide synthase expression by destabilizing mRNA in activated macrophages
-
Lahti A., Jalonen U., Kankaanranta H., and Moilanen E. c-Jun NH2-terminal kinase inhibitor anthra(1,9-cd)pyrazol-6(2H)-one reduces inducible nitric-oxide synthase expression by destabilizing mRNA in activated macrophages. Mol. Pharmacol. 64 (2003) 308-315
-
(2003)
Mol. Pharmacol.
, vol.64
, pp. 308-315
-
-
Lahti, A.1
Jalonen, U.2
Kankaanranta, H.3
Moilanen, E.4
-
105
-
-
0033049125
-
Evidence that tristetraprolin binds to AU-rich elements and promotes the deadenylation and destabilization of tumor necrosis factor alpha mRNA
-
Lai W.S., Carballo E., Strum J.R., Kennington E.A., Phillips R.S., and Blackshear P.J. Evidence that tristetraprolin binds to AU-rich elements and promotes the deadenylation and destabilization of tumor necrosis factor alpha mRNA. Mol. Cell. Biol. 19 (1999) 4311-4323
-
(1999)
Mol. Cell. Biol.
, vol.19
, pp. 4311-4323
-
-
Lai, W.S.1
Carballo, E.2
Strum, J.R.3
Kennington, E.A.4
Phillips, R.S.5
Blackshear, P.J.6
-
106
-
-
0034625369
-
Interactions of CCCH zinc finger proteins with mRNA. Binding of tristetraprolin-related zinc finger proteins to Au-rich elements and destabilization of mRNA
-
Lai W.S., Carballo E., Thorn J.M., Kennington E.A., and Blackshear P.J. Interactions of CCCH zinc finger proteins with mRNA. Binding of tristetraprolin-related zinc finger proteins to Au-rich elements and destabilization of mRNA. J. Biol. Chem. 275 (2000) 17827-17837
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 17827-17837
-
-
Lai, W.S.1
Carballo, E.2
Thorn, J.M.3
Kennington, E.A.4
Blackshear, P.J.5
-
107
-
-
0038751970
-
Tristetraprolin and its family members can promote the cell-free deadenylation of AU-rich element-containing mRNAs by poly(A) ribonuclease
-
Lai W.S., Kennington E.A., and Blackshear P.J. Tristetraprolin and its family members can promote the cell-free deadenylation of AU-rich element-containing mRNAs by poly(A) ribonuclease. Mol. Cell. Biol. 23 (2003) 3798-3812
-
(2003)
Mol. Cell. Biol.
, vol.23
, pp. 3798-3812
-
-
Lai, W.S.1
Kennington, E.A.2
Blackshear, P.J.3
-
108
-
-
4143122397
-
Concurrent versus individual binding of HuR and AUF1 to common labile target mRNAs
-
Lal A., Mazan-Mamczarz K., Kawai T., Yang X., Martindale J.L., and Gorospe M. Concurrent versus individual binding of HuR and AUF1 to common labile target mRNAs. EMBO J. 23 (2004) 3092-3102
-
(2004)
EMBO J.
, vol.23
, pp. 3092-3102
-
-
Lal, A.1
Mazan-Mamczarz, K.2
Kawai, T.3
Yang, X.4
Martindale, J.L.5
Gorospe, M.6
-
109
-
-
0034077529
-
Regulation of cyclooxygenase 2 mRNA stability by the mitogen-activated protein kinase p38 signaling cascade
-
Lasa M., Mahtani K.R., Finch A., Brewer G., Saklatvala J., and Clark A.R. Regulation of cyclooxygenase 2 mRNA stability by the mitogen-activated protein kinase p38 signaling cascade. Mol. Cell. Biol. 20 (2000) 4265-4274
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 4265-4274
-
-
Lasa, M.1
Mahtani, K.R.2
Finch, A.3
Brewer, G.4
Saklatvala, J.5
Clark, A.R.6
-
110
-
-
3843092621
-
Critical role for granulocyte colony-stimulating factor in inflammatory arthritis
-
Lawlor K.E., Campbell I.K., Metcalf D., O'Donnell K., van Nieuwenhuijze A., Roberts A.W., and Wicks I.P. Critical role for granulocyte colony-stimulating factor in inflammatory arthritis. Proc. Natl. Acad. Sci. USA 101 (2004) 11398-11403
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 11398-11403
-
-
Lawlor, K.E.1
Campbell, I.K.2
Metcalf, D.3
O'Donnell, K.4
van Nieuwenhuijze, A.5
Roberts, A.W.6
Wicks, I.P.7
-
111
-
-
0030044039
-
Post-transcriptional regulation of vascular endothelial growth factor by hypoxia
-
Levy A.P., Levy N.S., and Goldberg M.A. Post-transcriptional regulation of vascular endothelial growth factor by hypoxia. J. Biol. Chem. 271 (1996) 2746-2753
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 2746-2753
-
-
Levy, A.P.1
Levy, N.S.2
Goldberg, M.A.3
-
112
-
-
0032513043
-
Hypoxic stabilization of vascular endothelial growth factor mRNA by the RNA-binding protein HuR
-
Levy N.S., Chung S., Furneaux H., and Levy A.P. Hypoxic stabilization of vascular endothelial growth factor mRNA by the RNA-binding protein HuR. J. Biol. Chem. 273 (1998) 6417-6423
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 6417-6423
-
-
Levy, N.S.1
Chung, S.2
Furneaux, H.3
Levy, A.P.4
-
113
-
-
0024506159
-
Regulation of lymphokine messenger RNA stability by a surface-mediated T cell activation pathway
-
Lindsten T., June C.H., Ledbetter J.A., Stella G., and Thompson G.B. Regulation of lymphokine messenger RNA stability by a surface-mediated T cell activation pathway. Science 244 (1989) 339-343
-
(1989)
Science
, vol.244
, pp. 339-343
-
-
Lindsten, T.1
June, C.H.2
Ledbetter, J.A.3
Stella, G.4
Thompson, G.B.5
-
114
-
-
22144478256
-
MicroRNA-dependent localization of targeted mRNAs to mammalian P-bodies
-
Liu J., Valencia-Sanchez M.A., Hannon G.J., and Parker R. MicroRNA-dependent localization of targeted mRNAs to mammalian P-bodies. Nat. Cell Biol. 7 (2005) 719-723
-
(2005)
Nat. Cell Biol.
, vol.7
, pp. 719-723
-
-
Liu, J.1
Valencia-Sanchez, M.A.2
Hannon, G.J.3
Parker, R.4
-
115
-
-
0033565383
-
Unraveling a cytoplasmic role for hnRNP D in the in vivo mRNA destabilization directed by the AU-rich element
-
Loflin P., Chen C.Y., and Shyu A.B. Unraveling a cytoplasmic role for hnRNP D in the in vivo mRNA destabilization directed by the AU-rich element. Genes Dev. 13 (1999) 1884-1897
-
(1999)
Genes Dev.
, vol.13
, pp. 1884-1897
-
-
Loflin, P.1
Chen, C.Y.2
Shyu, A.B.3
-
116
-
-
27144434377
-
Identification and functional outcome of mRNAs associated with RNA-binding protein TIA-1
-
Lopez de Silanes I., Galban S., Martindale J.L., Yang X., Mazan-Mamczarz K., Indig F.E., Falco G., Zhan M., and Gorospe M. Identification and functional outcome of mRNAs associated with RNA-binding protein TIA-1. Mol. Cell. Biol. 25 (2005) 9520-9531
-
(2005)
Mol. Cell. Biol.
, vol.25
, pp. 9520-9531
-
-
Lopez de Silanes, I.1
Galban, S.2
Martindale, J.L.3
Yang, X.4
Mazan-Mamczarz, K.5
Indig, F.E.6
Falco, G.7
Zhan, M.8
Gorospe, M.9
-
117
-
-
1842529308
-
Tissue distribution of AU-rich mRNA-binding proteins involved in regulation of mRNA decay
-
Lu J.Y., and Schneider R.J. Tissue distribution of AU-rich mRNA-binding proteins involved in regulation of mRNA decay. J. Biol. Chem. 279 (2004) 12974-12979
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 12974-12979
-
-
Lu, J.Y.1
Schneider, R.J.2
-
118
-
-
13244298460
-
Recruitment and activation of mRNA decay enzymes by two ARE-mediated decay activation domains in the proteins TTP and BRF-1
-
Lykke-Andersen J., and Wagner E. Recruitment and activation of mRNA decay enzymes by two ARE-mediated decay activation domains in the proteins TTP and BRF-1. Genes Dev. 19 (2005) 351-361
-
(2005)
Genes Dev.
, vol.19
, pp. 351-361
-
-
Lykke-Andersen, J.1
Wagner, E.2
-
119
-
-
0029873536
-
Cloning and characterization of HuR, a ubiquitously expressed Elav-like protein
-
Ma W.-J., Cheng S., Campbell C., Wright A., and Furneaux H. Cloning and characterization of HuR, a ubiquitously expressed Elav-like protein. J. Biol. Chem. 271 (1996) 8144-8151
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 8144-8151
-
-
Ma, W.-J.1
Cheng, S.2
Campbell, C.3
Wright, A.4
Furneaux, H.5
-
121
-
-
0034816062
-
Mitogen-activated protein kinase p38 controls the expression and posttranslational modification of tristetraprolin, a regulator of tumor necrosis factor alpha mRNA stability
-
Mahtani K.R., Brook M., Dean J.L., Sully G., Saklatvala J., and Clark A.R. Mitogen-activated protein kinase p38 controls the expression and posttranslational modification of tristetraprolin, a regulator of tumor necrosis factor alpha mRNA stability. Mol. Cell. Biol. 21 (2001) 6461-6469
-
(2001)
Mol. Cell. Biol.
, vol.21
, pp. 6461-6469
-
-
Mahtani, K.R.1
Brook, M.2
Dean, J.L.3
Sully, G.4
Saklatvala, J.5
Clark, A.R.6
-
122
-
-
11144244014
-
Stabilization of IFN-gamma mRNA by MAPK p38 in IL-12- and IL-18-stimulated human NK cells
-
Mavropoulos A., Sully G., Cope A.P., and Clark A.R. Stabilization of IFN-gamma mRNA by MAPK p38 in IL-12- and IL-18-stimulated human NK cells. Blood 105 (2005) 282-288
-
(2005)
Blood
, vol.105
, pp. 282-288
-
-
Mavropoulos, A.1
Sully, G.2
Cope, A.P.3
Clark, A.R.4
-
123
-
-
0038153919
-
RNA-binding protein HuR enhances p53 translation in response to ultraviolet light irradiation
-
Mazan-Mamczarz K., Galban S., Lopez de Silanes I., Martindale J.L., Atasoy U., Keene J.D., and Gorospe M. RNA-binding protein HuR enhances p53 translation in response to ultraviolet light irradiation. Proc. Natl. Acad. Sci. USA 100 (2003) 8354-8359
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 8354-8359
-
-
Mazan-Mamczarz, K.1
Galban, S.2
Lopez de Silanes, I.3
Martindale, J.L.4
Atasoy, U.5
Keene, J.D.6
Gorospe, M.7
-
124
-
-
0030969572
-
A new regulatory protein, KSRP, mediates exon inclusion through an intronic splicing enhancer
-
Min H., Turck C.W., Nikolic J.M., and Black D.L. A new regulatory protein, KSRP, mediates exon inclusion through an intronic splicing enhancer. Genes Dev. 11 (1997) 1023-1036
-
(1997)
Genes Dev.
, vol.11
, pp. 1023-1036
-
-
Min, H.1
Turck, C.W.2
Nikolic, J.M.3
Black, D.L.4
-
125
-
-
0032531907
-
c-jun N-terminal kinase is involved in AUUUA-mediated interleukin-3 mRNA turnover in mast cells
-
Ming X.F., Kaiser M., and Moroni C. c-jun N-terminal kinase is involved in AUUUA-mediated interleukin-3 mRNA turnover in mast cells. EMBO J. 17 (1998) 6039-6048
-
(1998)
EMBO J.
, vol.17
, pp. 6039-6048
-
-
Ming, X.F.1
Kaiser, M.2
Moroni, C.3
-
126
-
-
0034907223
-
Parallel and Independent Regulation of Interleukin-3 mRNA Turnover by Phosphatidylinositol 3-Kinase and p38 Mitogen-Activated Protein Kinase
-
Ming X.F., Stoecklin G., Lu M., Looser R., and Moroni C. Parallel and Independent Regulation of Interleukin-3 mRNA Turnover by Phosphatidylinositol 3-Kinase and p38 Mitogen-Activated Protein Kinase. Mol. Cell. Biol. 21 (2001) 5778-5789
-
(2001)
Mol. Cell. Biol.
, vol.21
, pp. 5778-5789
-
-
Ming, X.F.1
Stoecklin, G.2
Lu, M.3
Looser, R.4
Moroni, C.5
-
127
-
-
0033785798
-
Musing on the structural organization of the exosome complex
-
Mitchell P., and Tollervey D. Musing on the structural organization of the exosome complex. Nat. Struct. Biol. 7 (2000) 843-846
-
(2000)
Nat. Struct. Biol.
, vol.7
, pp. 843-846
-
-
Mitchell, P.1
Tollervey, D.2
-
128
-
-
0034684283
-
Induction of collagenase-3 (MMP-13) in rheumatoid arthritis synovial fibroblasts
-
Moore B.A., Aznavoorian S., Engler J.A., and Windsor L.J. Induction of collagenase-3 (MMP-13) in rheumatoid arthritis synovial fibroblasts. Biochim. Biophys. Acta 1502 (2000) 307-318
-
(2000)
Biochim. Biophys. Acta
, vol.1502
, pp. 307-318
-
-
Moore, B.A.1
Aznavoorian, S.2
Engler, J.A.3
Windsor, L.J.4
-
130
-
-
0026751496
-
Alpha 4/beta 1 integrin (VLA-4) ligands in arthritis. Vascular cell adhesion molecule-1 expression in synovium and on fibroblast-like synoviocytes
-
Morales-Ducret J., Wayner E., Elices M.J., Alvaro-Gracia J.M., Zvaifler N.J., and Firestein G.S. Alpha 4/beta 1 integrin (VLA-4) ligands in arthritis. Vascular cell adhesion molecule-1 expression in synovium and on fibroblast-like synoviocytes. J. Immunol. 149 (1992) 1424-1431
-
(1992)
J. Immunol.
, vol.149
, pp. 1424-1431
-
-
Morales-Ducret, J.1
Wayner, E.2
Elices, M.J.3
Alvaro-Gracia, J.M.4
Zvaifler, N.J.5
Firestein, G.S.6
-
131
-
-
0037080834
-
The mammalian exosome mediates the efficient degradation of mRNAs that contain AU-rich elements
-
Mukherjee D., Gao M., O'Connor J.P., Raijmakers R., Pruijn G., Lutz C.S., and Wilusz J. The mammalian exosome mediates the efficient degradation of mRNAs that contain AU-rich elements. EMBO J. 21 (2002) 165-174
-
(2002)
EMBO J.
, vol.21
, pp. 165-174
-
-
Mukherjee, D.1
Gao, M.2
O'Connor, J.P.3
Raijmakers, R.4
Pruijn, G.5
Lutz, C.S.6
Wilusz, J.7
-
132
-
-
0037245474
-
Coupled mRNA stabilization and translational silencing of cyclooxygenase-2 by a novel RNA binding protein, CUGBP2
-
Mukhopadhyay D., Houchen C.W., Kennedy S., Dieckgraefe B.K., and Anant S. Coupled mRNA stabilization and translational silencing of cyclooxygenase-2 by a novel RNA binding protein, CUGBP2. Mol. Cell 11 (2003) 113-126
-
(2003)
Mol. Cell
, vol.11
, pp. 113-126
-
-
Mukhopadhyay, D.1
Houchen, C.W.2
Kennedy, S.3
Dieckgraefe, B.K.4
Anant, S.5
-
133
-
-
0035231369
-
DNA recognition by NF kappa B and STAT transcription factors
-
Muller C.W. DNA recognition by NF kappa B and STAT transcription factors. Ernst Schering Res. Found. Workshop 14 (2001) 3-166
-
(2001)
Ernst Schering Res. Found. Workshop
, vol.14
, pp. 3-166
-
-
Muller, C.W.1
-
134
-
-
4344598963
-
CD2-CD48 interactions promote interleukin-2 and interferon-gamma synthesis by stabilizing cytokine mRNA
-
Musgrave B.L., Watson C.L., Haeryfar S.M., Barnes C.A., and Hoskin D.W. CD2-CD48 interactions promote interleukin-2 and interferon-gamma synthesis by stabilizing cytokine mRNA. Cell. Immunol. 229 (2004) 1-12
-
(2004)
Cell. Immunol.
, vol.229
, pp. 1-12
-
-
Musgrave, B.L.1
Watson, C.L.2
Haeryfar, S.M.3
Barnes, C.A.4
Hoskin, D.W.5
-
135
-
-
0028357909
-
Cyclosporin A inhibits growth of autocrine tumour cell lines by destabilizing interleukin-3 mRNA
-
Nair A.P., Hahn S., Banholzer R., Hirsch H.H., and Moroni C. Cyclosporin A inhibits growth of autocrine tumour cell lines by destabilizing interleukin-3 mRNA. Nature 369 (1994) 239-242
-
(1994)
Nature
, vol.369
, pp. 239-242
-
-
Nair, A.P.1
Hahn, S.2
Banholzer, R.3
Hirsch, H.H.4
Moroni, C.5
-
136
-
-
0036479125
-
MK2 targets AU-rich elements and regulates biosynthesis of tumor necrosis factor and interleukin-6 independently at different post-transcriptional levels
-
Neininger A., Kontoyiannis D., Kotlyarov A., Winzen R., Eckert R., Volk H.D., Holtmann H., Kollias G., and Gaestel M. MK2 targets AU-rich elements and regulates biosynthesis of tumor necrosis factor and interleukin-6 independently at different post-transcriptional levels. J. Biol. Chem. 277 (2002) 3065-3068
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 3065-3068
-
-
Neininger, A.1
Kontoyiannis, D.2
Kotlyarov, A.3
Winzen, R.4
Eckert, R.5
Volk, H.D.6
Holtmann, H.7
Kollias, G.8
Gaestel, M.9
-
137
-
-
11844278314
-
Tristetraprolin down-regulates IL-2 gene expression through AU-rich element-mediated mRNA decay
-
Ogilvie R.L., Abelson M., Hau H.H., Vlasova I., Blackshear P.J., and Bohjanen P.R. Tristetraprolin down-regulates IL-2 gene expression through AU-rich element-mediated mRNA decay. J. Immunol. 174 (2005) 953-961
-
(2005)
J. Immunol.
, vol.174
, pp. 953-961
-
-
Ogilvie, R.L.1
Abelson, M.2
Hau, H.H.3
Vlasova, I.4
Blackshear, P.J.5
Bohjanen, P.R.6
-
138
-
-
0035951373
-
Lipoxygense mRNA silencing in erythroid differentiation: The 3′ UTR regulatory complex controls 60S ribosomal subunit joining
-
Ostareck D., Ostareck-Lederer A., Shatsky I., and Hentze M. Lipoxygense mRNA silencing in erythroid differentiation: The 3′ UTR regulatory complex controls 60S ribosomal subunit joining. Cell 104 (2001) 281-290
-
(2001)
Cell
, vol.104
, pp. 281-290
-
-
Ostareck, D.1
Ostareck-Lederer, A.2
Shatsky, I.3
Hentze, M.4
-
139
-
-
0030772963
-
mRNA silencing in erythroid differentiation: hnRNP K and hnRNP E1 regulate 15-lipoxygenase translation from the 3′ end
-
Ostareck D.H., Ostareck-Lederer A., Wilm M., Thiele B.J., Mann M., and Hentze M.W. mRNA silencing in erythroid differentiation: hnRNP K and hnRNP E1 regulate 15-lipoxygenase translation from the 3′ end. Cell 89 (1997) 597-606
-
(1997)
Cell
, vol.89
, pp. 597-606
-
-
Ostareck, D.H.1
Ostareck-Lederer, A.2
Wilm, M.3
Thiele, B.J.4
Mann, M.5
Hentze, M.W.6
-
140
-
-
0037380693
-
Single-dose pharmacokinetics and pharmacodynamics of RWJ 67657, a specific p38 mitogen-activated protein kinase inhibitor: A first-in-human study
-
Parasrampuria D.A., de Boer P., Desai-Krieger D., Chow A.T., and Jones C.R. Single-dose pharmacokinetics and pharmacodynamics of RWJ 67657, a specific p38 mitogen-activated protein kinase inhibitor: A first-in-human study. J. Clin. Pharmacol. 43 (2003) 406-413
-
(2003)
J. Clin. Pharmacol.
, vol.43
, pp. 406-413
-
-
Parasrampuria, D.A.1
de Boer, P.2
Desai-Krieger, D.3
Chow, A.T.4
Jones, C.R.5
-
141
-
-
0038179379
-
Inhibitors of p38 mitogen-activated protein kinase for the treatment of rheumatoid arthritis
-
Pargellis C., and Regan J. Inhibitors of p38 mitogen-activated protein kinase for the treatment of rheumatoid arthritis. Curr. Opin. Investig. Drugs 4 (2003) 566-571
-
(2003)
Curr. Opin. Investig. Drugs
, vol.4
, pp. 566-571
-
-
Pargellis, C.1
Regan, J.2
-
142
-
-
0742288008
-
The enzymes and control of eukaryotic mRNA turnover
-
Parker R., and Song H. The enzymes and control of eukaryotic mRNA turnover. Nat. Struct. Mol. Biol. 11 (2004) 121-127
-
(2004)
Nat. Struct. Mol. Biol.
, vol.11
, pp. 121-127
-
-
Parker, R.1
Song, H.2
-
143
-
-
17044392271
-
ERK1/2 regulates epidermal chemokine expression and skin inflammation
-
Pastore S., Mascia F., Mariotti F., Dattilo C., Mariani V., and Girolomoni G. ERK1/2 regulates epidermal chemokine expression and skin inflammation. J. Immunol. 174 (2005) 5047-5056
-
(2005)
J. Immunol.
, vol.174
, pp. 5047-5056
-
-
Pastore, S.1
Mascia, F.2
Mariotti, F.3
Dattilo, C.4
Mariani, V.5
Girolomoni, G.6
-
144
-
-
0032526417
-
RNA stabilization by the AU-rich element binding protein, HuR, an ELAV protein
-
Peng S.S., Chen C.Y., Xu N., and Shyu A.B. RNA stabilization by the AU-rich element binding protein, HuR, an ELAV protein. EMBO J. 17 (1998) 3461-3470
-
(1998)
EMBO J.
, vol.17
, pp. 3461-3470
-
-
Peng, S.S.1
Chen, C.Y.2
Xu, N.3
Shyu, A.B.4
-
145
-
-
0034990918
-
Posttranscriptional regulation of human iNOS by the NO/cGMP pathway
-
Perez-Sala D., Cernuda-Morollon E., Diaz-Cazorla M., Rodriguez-Pascual F., and Lamas S. Posttranscriptional regulation of human iNOS by the NO/cGMP pathway. Am. J. Physiol. Renal Physiol. 280 (2001) F466-F473
-
(2001)
Am. J. Physiol. Renal Physiol.
, vol.280
-
-
Perez-Sala, D.1
Cernuda-Morollon, E.2
Diaz-Cazorla, M.3
Rodriguez-Pascual, F.4
Lamas, S.5
-
146
-
-
1242341962
-
Arthritis suppressor genes TIA-1 and TTP dampen the expression of tumor necrosis factor alpha, cyclooxygenase 2, and inflammatory arthritis
-
Phillips K., Kedersha N., Shen L., Blackshear P.J., and Anderson P. Arthritis suppressor genes TIA-1 and TTP dampen the expression of tumor necrosis factor alpha, cyclooxygenase 2, and inflammatory arthritis. Proc. Natl. Acad. Sci. USA 101 (2004) 2011-2016
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 2011-2016
-
-
Phillips, K.1
Kedersha, N.2
Shen, L.3
Blackshear, P.J.4
Anderson, P.5
-
147
-
-
0034254553
-
TIA-1 is a translational silencer that selectively regulates the expression of TNF-alpha
-
Piecyk M., Wax S., Beck A.R., Kedersha N., Gupta M., Maritim B., Chen S., Gueydan C., Kruys V., Streuli M., and Anderson P. TIA-1 is a translational silencer that selectively regulates the expression of TNF-alpha. EMBO J. 19 (2000) 4154-4163
-
(2000)
EMBO J.
, vol.19
, pp. 4154-4163
-
-
Piecyk, M.1
Wax, S.2
Beck, A.R.3
Kedersha, N.4
Gupta, M.5
Maritim, B.6
Chen, S.7
Gueydan, C.8
Kruys, V.9
Streuli, M.10
Anderson, P.11
-
149
-
-
0036183551
-
RNA destabilization by the granulocyte colony-stimulating factor stem-loop destabilizing element involves a single stem-loop that promotes deadenylation
-
Putland R.A., Sassinis T.A., Harvey J.S., Diamond P., Coles L.S., Brown C.Y., and Goodall G.J. RNA destabilization by the granulocyte colony-stimulating factor stem-loop destabilizing element involves a single stem-loop that promotes deadenylation. Mol. Cell. Biol. 22 (2002) 1664-1673
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 1664-1673
-
-
Putland, R.A.1
Sassinis, T.A.2
Harvey, J.S.3
Diamond, P.4
Coles, L.S.5
Brown, C.Y.6
Goodall, G.J.7
-
150
-
-
0037109118
-
Expression of the human RNA-binding protein HuR in Trypanosoma brucei increases the abundance of mRNAs containing AU-rich regulatory elements
-
Quijada L., Guerra-Giraldez C., Drozdz M., Hartmann C., Irmer H., Ben-Dov C., Cristodero M., Ding M., and Clayton C. Expression of the human RNA-binding protein HuR in Trypanosoma brucei increases the abundance of mRNAs containing AU-rich regulatory elements. Nucleic Acids Res. 30 (2002) 4414-4424
-
(2002)
Nucleic Acids Res.
, vol.30
, pp. 4414-4424
-
-
Quijada, L.1
Guerra-Giraldez, C.2
Drozdz, M.3
Hartmann, C.4
Irmer, H.5
Ben-Dov, C.6
Cristodero, M.7
Ding, M.8
Clayton, C.9
-
151
-
-
0035930565
-
HuA and tristetraprolin are induced following T cell activation and display distinct but overlapping RNA binding specificities
-
Raghavan A., Robison R.L., McNabb J., Miller C.R., Williams D.A., and Bohjanen P.R. HuA and tristetraprolin are induced following T cell activation and display distinct but overlapping RNA binding specificities. J. Biol. Chem. 276 (2001) 47958-47965
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 47958-47965
-
-
Raghavan, A.1
Robison, R.L.2
McNabb, J.3
Miller, C.R.4
Williams, D.A.5
Bohjanen, P.R.6
-
152
-
-
4344573414
-
The exosome, a molecular machine for controlled RNA degradation in both nucleus and cytoplasm
-
Raijmakers R., Schilders G., and Pruijn G.J. The exosome, a molecular machine for controlled RNA degradation in both nucleus and cytoplasm. Eur. J. Cell Biol. 83 (2004) 175-183
-
(2004)
Eur. J. Cell Biol.
, vol.83
, pp. 175-183
-
-
Raijmakers, R.1
Schilders, G.2
Pruijn, G.J.3
-
153
-
-
2542596992
-
Roles of AUF1 isoforms, HuR and BRF1 in ARE-dependent mRNA turnover studied by RNA interference
-
Raineri I., Wegmueller D., Gross B., Certa U., and Moroni C. Roles of AUF1 isoforms, HuR and BRF1 in ARE-dependent mRNA turnover studied by RNA interference. Nucleic Acids Res. 32 (2004) 1279-1288
-
(2004)
Nucleic Acids Res.
, vol.32
, pp. 1279-1288
-
-
Raineri, I.1
Wegmueller, D.2
Gross, B.3
Certa, U.4
Moroni, C.5
-
154
-
-
0000150893
-
Two levels of regulation of beta-interferon gene expression in human cells
-
Raj N.B., and Pitha P.M. Two levels of regulation of beta-interferon gene expression in human cells. Proc. Natl. Acad. Sci. USA 80 (1983) 3923-3927
-
(1983)
Proc. Natl. Acad. Sci. USA
, vol.80
, pp. 3923-3927
-
-
Raj, N.B.1
Pitha, P.M.2
-
155
-
-
7244254455
-
The CCCH tandem zinc-finger protein Zfp36l2 is crucial for female fertility and early embryonic development
-
Ramos S.B., Stumpo D.J., Kennington E.A., Phillips R.S., Bock C.B., Ribeiro-Neto F., and Blackshear P.J. The CCCH tandem zinc-finger protein Zfp36l2 is crucial for female fertility and early embryonic development. Development 131 (2004) 4883-4893
-
(2004)
Development
, vol.131
, pp. 4883-4893
-
-
Ramos, S.B.1
Stumpo, D.J.2
Kennington, E.A.3
Phillips, R.S.4
Bock, C.B.5
Ribeiro-Neto, F.6
Blackshear, P.J.7
-
156
-
-
0032515186
-
A p38 MAP kinase inhibitor regulates stability of interleukin-1-induced cyclooxygenase-2 mRNA
-
Ridley S.H., Dean J.L., Sarsfield S.J., Brook M., Clark A.R., and Saklatvala J. A p38 MAP kinase inhibitor regulates stability of interleukin-1-induced cyclooxygenase-2 mRNA. FEBS Lett. 439 (1998) 75-80
-
(1998)
FEBS Lett.
, vol.439
, pp. 75-80
-
-
Ridley, S.H.1
Dean, J.L.2
Sarsfield, S.J.3
Brook, M.4
Clark, A.R.5
Saklatvala, J.6
-
157
-
-
20444414937
-
Structure/Function Analysis of Tristetraprolin (TTP): p38 Stress-Activated Protein Kinase and Lipopolysaccharide Stimulation Do Not Alter TTP Function
-
Rigby W.F., Roy K., Collins J., Rigby S., Connolly J.E., Bloch D.B., and Brooks S.A. Structure/Function Analysis of Tristetraprolin (TTP): p38 Stress-Activated Protein Kinase and Lipopolysaccharide Stimulation Do Not Alter TTP Function. J. Immunol. 174 (2005) 7883-7893
-
(2005)
J. Immunol.
, vol.174
, pp. 7883-7893
-
-
Rigby, W.F.1
Roy, K.2
Collins, J.3
Rigby, S.4
Connolly, J.E.5
Bloch, D.B.6
Brooks, S.A.7
-
158
-
-
0028180129
-
Induction of cyclooxygenase-2 by interleukin-1 alpha. Evidence for post-transcriptional regulation
-
Ristimaki A., Garfinkel S., Wessendorf J., Maciag T., and Hla T. Induction of cyclooxygenase-2 by interleukin-1 alpha. Evidence for post-transcriptional regulation. J. Biol. Chem. 269 (1994) 11769-11775
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 11769-11775
-
-
Ristimaki, A.1
Garfinkel, S.2
Wessendorf, J.3
Maciag, T.4
Hla, T.5
-
159
-
-
0034714259
-
Complex contribution of the 3′-untranslated region to the expressional regulation of the human inducible nitric-oxide synthase gene. Involvement of the RNA-binding protein HuR
-
Rodriguez-Pascual F., Hausding M., Ihrig-Biedert I., Furneaux H., Levy A.P., Forstermann U., and Kleinert H. Complex contribution of the 3′-untranslated region to the expressional regulation of the human inducible nitric-oxide synthase gene. Involvement of the RNA-binding protein HuR. J. Biol. Chem. 275 (2000) 26040-26049
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 26040-26049
-
-
Rodriguez-Pascual, F.1
Hausding, M.2
Ihrig-Biedert, I.3
Furneaux, H.4
Levy, A.P.5
Forstermann, U.6
Kleinert, H.7
-
160
-
-
0037011121
-
Inhibition of SAPK2a/p38 prevents hnRNP A0 phosphorylation by MAPKAP-K2 and its interaction with cytokine mRNAs
-
Rousseau S., Morrice N., Peggie M., Campbell D.G., Gaestel M., and Cohen P. Inhibition of SAPK2a/p38 prevents hnRNP A0 phosphorylation by MAPKAP-K2 and its interaction with cytokine mRNAs. EMBO J. 21 (2002) 6505-6514
-
(2002)
EMBO J.
, vol.21
, pp. 6505-6514
-
-
Rousseau, S.1
Morrice, N.2
Peggie, M.3
Campbell, D.G.4
Gaestel, M.5
Cohen, P.6
-
161
-
-
0035677246
-
TIA-1 regulates the production of tumor necrosis factor alpha in macrophages, but not in lymphocytes
-
Saito K., Chen S., Piecyk M., and Anderson P. TIA-1 regulates the production of tumor necrosis factor alpha in macrophages, but not in lymphocytes. Arthritis Rheum. 44 (2001) 2879-2887
-
(2001)
Arthritis Rheum.
, vol.44
, pp. 2879-2887
-
-
Saito, K.1
Chen, S.2
Piecyk, M.3
Anderson, P.4
-
162
-
-
0041689753
-
Selective degradation of AU-rich mRNAs promoted by the p37 AUF1 protein isoform
-
Sarkar B., Xi Q., He C., and Schneider R.J. Selective degradation of AU-rich mRNAs promoted by the p37 AUF1 protein isoform. Mol. Cell. Biol. 23 (2003) 6685-6693
-
(2003)
Mol. Cell. Biol.
, vol.23
, pp. 6685-6693
-
-
Sarkar, B.1
Xi, Q.2
He, C.3
Schneider, R.J.4
-
163
-
-
19944426618
-
The ARE-dependent mRNA-destabilizing activity of BRF1 is regulated by protein kinase B
-
Schmidlin M., Lu M., Leuenberger S.A., Stoecklin G., Mallaun M., Gross B., Gherzi R., Hess D., Hemmings B.A., and Moroni C. The ARE-dependent mRNA-destabilizing activity of BRF1 is regulated by protein kinase B. EMBO J. 23 (2004) 4760-4769
-
(2004)
EMBO J.
, vol.23
, pp. 4760-4769
-
-
Schmidlin, M.1
Lu, M.2
Leuenberger, S.A.3
Stoecklin, G.4
Mallaun, M.5
Gross, B.6
Gherzi, R.7
Hess, D.8
Hemmings, B.A.9
Moroni, C.10
-
164
-
-
0038016230
-
COX-2-selective inhibitors in the treatment of arthritis
-
Schnitzer T.J., and Hochberg M.C. COX-2-selective inhibitors in the treatment of arthritis. Cleve. Clin. J. Med. 69 Suppl. 1 (2002) SI20-SI30
-
(2002)
Cleve. Clin. J. Med.
, vol.69
, Issue.SUPPL. 1
-
-
Schnitzer, T.J.1
Hochberg, M.C.2
-
165
-
-
0034910202
-
Lipoxins and aspirin-triggered 15-epi-lipoxins are endogenous components of antiinflammation: Emergence of the counterregulatory side
-
Serhan C.N. Lipoxins and aspirin-triggered 15-epi-lipoxins are endogenous components of antiinflammation: Emergence of the counterregulatory side. Arch. Immunol. Ther. Exp. (Warsz) 49 (2001) 177-188
-
(2001)
Arch. Immunol. Ther. Exp. (Warsz)
, vol.49
, pp. 177-188
-
-
Serhan, C.N.1
-
166
-
-
0023058975
-
A conserved AU sequence from the 3′untranslated region of GM-CSF mRNA mediates selective mRNA degradation
-
Shaw G., and Kamen R. A conserved AU sequence from the 3′untranslated region of GM-CSF mRNA mediates selective mRNA degradation. Cell 46 (1986) 659-667
-
(1986)
Cell
, vol.46
, pp. 659-667
-
-
Shaw, G.1
Kamen, R.2
-
167
-
-
0030978801
-
Adhesion-dependent regulation of an A + U-rich element-binding activity associated with AUF1
-
Sirenko O.I., Lofquist A.K., De Maria C.T., Morris J.S., Brewer G., and Haskill J.S. Adhesion-dependent regulation of an A + U-rich element-binding activity associated with AUF1. Mol. Cell. Biol. 17 (1997) 3898-3906
-
(1997)
Mol. Cell. Biol.
, vol.17
, pp. 3898-3906
-
-
Sirenko, O.I.1
Lofquist, A.K.2
De Maria, C.T.3
Morris, J.S.4
Brewer, G.5
Haskill, J.S.6
-
168
-
-
0033962298
-
A mammalian homologue of GCN2 protein kinase important for translational control by phosphorylation of eukaryotic initiation factor-2alpha
-
Sood R., Porter A.C., Olsen D.A., Cavener D.R., and Wek R.C. A mammalian homologue of GCN2 protein kinase important for translational control by phosphorylation of eukaryotic initiation factor-2alpha. Genetics 154 (2000) 787-801
-
(2000)
Genetics
, vol.154
, pp. 787-801
-
-
Sood, R.1
Porter, A.C.2
Olsen, D.A.3
Cavener, D.R.4
Wek, R.C.5
-
169
-
-
0029082384
-
Stabilization of vascular endothelial growth factor mRNA by hypoxia and hypoglycemia and coregulation with other ischemia-induced genes
-
Stein I., Neeman M., Shweiki D., Itin A., and Keshet E. Stabilization of vascular endothelial growth factor mRNA by hypoxia and hypoglycemia and coregulation with other ischemia-induced genes. Mol. Cell. Biol. 15 (1995) 5363-5368
-
(1995)
Mol. Cell. Biol.
, vol.15
, pp. 5363-5368
-
-
Stein, I.1
Neeman, M.2
Shweiki, D.3
Itin, A.4
Keshet, E.5
-
170
-
-
0026018987
-
Post-transcriptional regulation of gro alpha, beta, gamma, and IL-8 mRNAs by IL-1 beta
-
Stoeckle M.Y. Post-transcriptional regulation of gro alpha, beta, gamma, and IL-8 mRNAs by IL-1 beta. Nucleic Acids Res. 19 (1991) 917-920
-
(1991)
Nucleic Acids Res.
, vol.19
, pp. 917-920
-
-
Stoeckle, M.Y.1
-
171
-
-
18544370404
-
Functional cloning of BRF1, a regulator of ARE-dependent mRNA turnover
-
Stoecklin G., Colombi M., Raineri I., Leuenberger S., Mallaun M., Schmidlin M., Gross B., Lu M., Kitamura T., and Moroni C. Functional cloning of BRF1, a regulator of ARE-dependent mRNA turnover. EMBO J. 21 (2002) 4709-4718
-
(2002)
EMBO J.
, vol.21
, pp. 4709-4718
-
-
Stoecklin, G.1
Colombi, M.2
Raineri, I.3
Leuenberger, S.4
Mallaun, M.5
Schmidlin, M.6
Gross, B.7
Lu, M.8
Kitamura, T.9
Moroni, C.10
-
172
-
-
0028172176
-
Functional hierarchy of AUUUA motifs in mediating rapid interleukin-3 mRNA decay
-
Stoecklin G., Hahn S., and Moroni C. Functional hierarchy of AUUUA motifs in mediating rapid interleukin-3 mRNA decay. J. Biol. Chem. 269 (1994) 28591-28597
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 28591-28597
-
-
Stoecklin, G.1
Hahn, S.2
Moroni, C.3
-
173
-
-
0038641941
-
A constitutive decay element promotes tumor necrosis factor alpha mRNA degradation via an AU-rich element-independent pathway
-
Stoecklin G., Lu M., Rattenbacher B., and Moroni C. A constitutive decay element promotes tumor necrosis factor alpha mRNA degradation via an AU-rich element-independent pathway. Mol. Cell. Biol. 23 (2003) 3506-3515
-
(2003)
Mol. Cell. Biol.
, vol.23
, pp. 3506-3515
-
-
Stoecklin, G.1
Lu, M.2
Rattenbacher, B.3
Moroni, C.4
-
174
-
-
33646200678
-
ARE-mRNA degradation requires the 5′-3′ decay pathway
-
In Press.
-
Stoecklin G., Mayo T., and Anderson P. ARE-mRNA degradation requires the 5′-3′ decay pathway. EMBO Rep. (2005) In Press.
-
(2005)
EMBO Rep.
-
-
Stoecklin, G.1
Mayo, T.2
Anderson, P.3
-
175
-
-
0034073984
-
Somatic mRNA turnover mutants implicate tristetraprolin in the interleukin-3 mRNA degradation pathway
-
Stoecklin G., Ming X.F., Looser R., and Moroni C. Somatic mRNA turnover mutants implicate tristetraprolin in the interleukin-3 mRNA degradation pathway. Mol. Cell. Biol. 20 (2000) 3753-3763
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 3753-3763
-
-
Stoecklin, G.1
Ming, X.F.2
Looser, R.3
Moroni, C.4
-
176
-
-
0035161588
-
Cellular mutants define a common mRNA degradation pathway targeting cytokine AU-rich elements
-
Stoecklin G., Stoeckle P., Lu M., Muehlemann O., and Moroni C. Cellular mutants define a common mRNA degradation pathway targeting cytokine AU-rich elements. RNA 7 (2001) 1578-1588
-
(2001)
RNA
, vol.7
, pp. 1578-1588
-
-
Stoecklin, G.1
Stoeckle, P.2
Lu, M.3
Muehlemann, O.4
Moroni, C.5
-
177
-
-
1942471656
-
MK2-induced tristetraprolin:14-3-3 complexes prevent stress granule association and ARE-mRNA decay
-
Stoecklin G., Stubbs T., Kedersha N., Wax S., Rigby W.F., Blackwell T.K., and Anderson P. MK2-induced tristetraprolin:14-3-3 complexes prevent stress granule association and ARE-mRNA decay. EMBO J. 23 (2004) 1313-1324
-
(2004)
EMBO J.
, vol.23
, pp. 1313-1324
-
-
Stoecklin, G.1
Stubbs, T.2
Kedersha, N.3
Wax, S.4
Rigby, W.F.5
Blackwell, T.K.6
Anderson, P.7
-
178
-
-
3042714493
-
Chorioallantoic fusion defects and embryonic lethality resulting from disruption of Zfp36L1, a gene encoding a CCCH tandem zinc finger protein of the Tristetraprolin family
-
Stumpo D.J., Byrd N.A., Phillips R.S., Ghosh S., Maronpot R.R., Castranio T., Meyers E.N., Mishina Y., and Blackshear P.J. Chorioallantoic fusion defects and embryonic lethality resulting from disruption of Zfp36L1, a gene encoding a CCCH tandem zinc finger protein of the Tristetraprolin family. Mol. Cell. Biol. 24 (2004) 6445-6455
-
(2004)
Mol. Cell. Biol.
, vol.24
, pp. 6445-6455
-
-
Stumpo, D.J.1
Byrd, N.A.2
Phillips, R.S.3
Ghosh, S.4
Maronpot, R.R.5
Castranio, T.6
Meyers, E.N.7
Mishina, Y.8
Blackshear, P.J.9
-
179
-
-
0035260745
-
COX-2 inhibitors in rheumatoid arthritis
-
Sundy J.S. COX-2 inhibitors in rheumatoid arthritis. Curr. Rheumatol. Rep. 3 (2001) 86-91
-
(2001)
Curr. Rheumatol. Rep.
, vol.3
, pp. 86-91
-
-
Sundy, J.S.1
-
180
-
-
0033034365
-
Enhanced Th1 activity and development of chronic enterocolitis in mice devoid of Stat3 in macrophages and neutrophils
-
Takeda K., Clausen B.E., Kaisho T., Tsujimura T., Terada N., Forster I., and Akira S. Enhanced Th1 activity and development of chronic enterocolitis in mice devoid of Stat3 in macrophages and neutrophils. Immunity 10 (1999) 39-49
-
(1999)
Immunity
, vol.10
, pp. 39-49
-
-
Takeda, K.1
Clausen, B.E.2
Kaisho, T.3
Tsujimura, T.4
Terada, N.5
Forster, I.6
Akira, S.7
-
181
-
-
16044369031
-
A pathogenetic role for TNF alpha in the syndrome of cachexia, arthritis, and autoimmunity resulting from tristetraprolin (TTP) deficiency
-
Taylor G.A., Carballo E., Lee D.M., Lai W.S., Thompson M.J., Patel D.D., Schenkman D.I., Gilkeson G.S., Broxmeyer H.E., Haynes B.F., and Blackshear P.J. A pathogenetic role for TNF alpha in the syndrome of cachexia, arthritis, and autoimmunity resulting from tristetraprolin (TTP) deficiency. Immunity 4 (1996) 445-454
-
(1996)
Immunity
, vol.4
, pp. 445-454
-
-
Taylor, G.A.1
Carballo, E.2
Lee, D.M.3
Lai, W.S.4
Thompson, M.J.5
Patel, D.D.6
Schenkman, D.I.7
Gilkeson, G.S.8
Broxmeyer, H.E.9
Haynes, B.F.10
Blackshear, P.J.11
-
182
-
-
1642523679
-
Facilitation of mRNA deadenylation and decay by the exosome-bound, DExH protein RHAU
-
Tran H., Schilling M., Wirbelauer C., Hess D., and Nagamine Y. Facilitation of mRNA deadenylation and decay by the exosome-bound, DExH protein RHAU. Mol. Cell 13 (2004) 101-111
-
(2004)
Mol. Cell
, vol.13
, pp. 101-111
-
-
Tran, H.1
Schilling, M.2
Wirbelauer, C.3
Hess, D.4
Nagamine, Y.5
-
183
-
-
0037121926
-
Human Dcp2: A catalytically active mRNA decapping enzyme located in specific cytoplasmic structures
-
van Dijk E., Cougot N., Meyer S., Babajko S., Wahle E., and Seraphin B. Human Dcp2: A catalytically active mRNA decapping enzyme located in specific cytoplasmic structures. EMBO J. 21 (2002) 6915-6924
-
(2002)
EMBO J.
, vol.21
, pp. 6915-6924
-
-
van Dijk, E.1
Cougot, N.2
Meyer, S.3
Babajko, S.4
Wahle, E.5
Seraphin, B.6
-
184
-
-
0032563812
-
A function for lipoxygenase in programmed organelle degradation
-
van Leyen K., Duvoisin R.M., Engelhardt H., and Wiedmann M. A function for lipoxygenase in programmed organelle degradation. Nature 395 (1998) 392-395
-
(1998)
Nature
, vol.395
, pp. 392-395
-
-
van Leyen, K.1
Duvoisin, R.M.2
Engelhardt, H.3
Wiedmann, M.4
-
185
-
-
0026031875
-
The TIS11 primary response gene is a member of a gene family that encodes proteins with a highly conserved sequence containing an unusual Cys-His repeat
-
Varnum B.C., Ma Q.F., Chi T.H., Fletcher B., and Herschman H.R. The TIS11 primary response gene is a member of a gene family that encodes proteins with a highly conserved sequence containing an unusual Cys-His repeat. Mol. Cell. Biol. 11 (1991) 1754-1758
-
(1991)
Mol. Cell. Biol.
, vol.11
, pp. 1754-1758
-
-
Varnum, B.C.1
Ma, Q.F.2
Chi, T.H.3
Fletcher, B.4
Herschman, H.R.5
-
186
-
-
0034964525
-
Regulated ARE-mediated mRNA decay in Saccharomyces cerevisiae
-
Vasudevan S., and Peltz S.W. Regulated ARE-mediated mRNA decay in Saccharomyces cerevisiae. Mol. Cell 7 (2001) 1191-1200
-
(2001)
Mol. Cell
, vol.7
, pp. 1191-1200
-
-
Vasudevan, S.1
Peltz, S.W.2
-
187
-
-
0036240838
-
Transcriptional regulation of collagenase (MMP-1, MMP-13) genes in arthritis: Integration of complex signaling pathways for the recruitment of gene-specific transcription factors
-
Vincenti M.P., and Brinckerhoff C.E. Transcriptional regulation of collagenase (MMP-1, MMP-13) genes in arthritis: Integration of complex signaling pathways for the recruitment of gene-specific transcription factors. Arthritis Res. 4 (2002) 157-164
-
(2002)
Arthritis Res.
, vol.4
, pp. 157-164
-
-
Vincenti, M.P.1
Brinckerhoff, C.E.2
-
188
-
-
14844312896
-
The Epstein-Barr virus oncoprotein latent membrane protein 1 induces expression of the chemokine IP-10: Importance of mRNA half-life regulation
-
Vockerodt M., Pinkert D., Smola-Hess S., Michels A., Ransohoff R.M., Tesch H., and Kube D. The Epstein-Barr virus oncoprotein latent membrane protein 1 induces expression of the chemokine IP-10: Importance of mRNA half-life regulation. Int. J. Cancer 114 (2005) 598-605
-
(2005)
Int. J. Cancer
, vol.114
, pp. 598-605
-
-
Vockerodt, M.1
Pinkert, D.2
Smola-Hess, S.3
Michels, A.4
Ransohoff, R.M.5
Tesch, H.6
Kube, D.7
-
189
-
-
11844298901
-
Transcriptional regulation of the metazoan stress protein response
-
Voellmy R. Transcriptional regulation of the metazoan stress protein response. Prog. Nucleic Acid Res. Mol. Biol. 78 (2004) 143-185
-
(2004)
Prog. Nucleic Acid Res. Mol. Biol.
, vol.78
, pp. 143-185
-
-
Voellmy, R.1
-
190
-
-
0032033151
-
Structure and genomic organization of the human AUF1 gene: Alternative pre-mRNA splicing generates four protein isoforms
-
Wagner B.J., De Maria C.T., Sun Y., Wilson G.M., and Brewer G. Structure and genomic organization of the human AUF1 gene: Alternative pre-mRNA splicing generates four protein isoforms. Genomics 48 (1998) 195-202
-
(1998)
Genomics
, vol.48
, pp. 195-202
-
-
Wagner, B.J.1
De Maria, C.T.2
Sun, Y.3
Wilson, G.M.4
Brewer, G.5
-
191
-
-
0034657686
-
HuR regulates cyclin A and cyclin B1 mRNA stability during cell proliferation
-
Wang W., Caldwell M.C., Lin S., Furneaux H., and Gorospe M. HuR regulates cyclin A and cyclin B1 mRNA stability during cell proliferation. EMBO J. 19 (2000) 2340-2350
-
(2000)
EMBO J.
, vol.19
, pp. 2340-2350
-
-
Wang, W.1
Caldwell, M.C.2
Lin, S.3
Furneaux, H.4
Gorospe, M.5
-
192
-
-
0037197892
-
Precision and functional specificity in mRNA decay
-
Wang Y., Liu C., Storey J., Tibshirani R., Herschlag D., and Brown P. Precision and functional specificity in mRNA decay. Proc. Natl. Acad. Sci. USA 99 (2002) 5860-5865
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 5860-5865
-
-
Wang, Y.1
Liu, C.2
Storey, J.3
Tibshirani, R.4
Herschlag, D.5
Brown, P.6
-
193
-
-
0036161788
-
Stimulation of collagenase 3 expression in synovial fibroblasts of patients with rheumatoid arthritis by contact with a three-dimensional collagen matrix or with normal cartilage when coimplanted in NOD/SCID mice
-
Wernicke D., Schulze-Westhoff C., Brauer R., Petrow P., Zacher J., Gay S., and Gromnica-Ihle E. Stimulation of collagenase 3 expression in synovial fibroblasts of patients with rheumatoid arthritis by contact with a three-dimensional collagen matrix or with normal cartilage when coimplanted in NOD/SCID mice. Arthritis Rheum. 46 (2002) 64-74
-
(2002)
Arthritis Rheum.
, vol.46
, pp. 64-74
-
-
Wernicke, D.1
Schulze-Westhoff, C.2
Brauer, R.3
Petrow, P.4
Zacher, J.5
Gay, S.6
Gromnica-Ihle, E.7
-
194
-
-
7244243748
-
Strong inhibition of TNF-alpha production and inhibition of IL-8 and COX-2 mRNA expression in monocyte-derived macrophages by RWJ 67657, a p38 mitogen-activated protein kinase (MAPK) inhibitor
-
Westra J., Doornbos-van der Meer B., de Boer P., van Leeuwen M.A., van Rijswijk M.H., and Limburg P.C. Strong inhibition of TNF-alpha production and inhibition of IL-8 and COX-2 mRNA expression in monocyte-derived macrophages by RWJ 67657, a p38 mitogen-activated protein kinase (MAPK) inhibitor. Arthritis Res. Ther. 6 (2004) R384-R392
-
(2004)
Arthritis Res. Ther.
, vol.6
-
-
Westra, J.1
Doornbos-van der Meer, B.2
de Boer, P.3
van Leeuwen, M.A.4
van Rijswijk, M.H.5
Limburg, P.C.6
-
195
-
-
19444379617
-
Chemokine production and E-selectin expression in activated endothelial cells are inhibited by p38 MAPK (mitogen activated protein kinase) inhibitor RWJ 67657
-
Westra J., Kuldo J.M., van Rijswijk M.H., Molema G., and Limburg P.C. Chemokine production and E-selectin expression in activated endothelial cells are inhibited by p38 MAPK (mitogen activated protein kinase) inhibitor RWJ 67657. Int. Immunopharmacol. 5 (2005) 1259-1269
-
(2005)
Int. Immunopharmacol.
, vol.5
, pp. 1259-1269
-
-
Westra, J.1
Kuldo, J.M.2
van Rijswijk, M.H.3
Molema, G.4
Limburg, P.C.5
-
196
-
-
7244254315
-
Effects of RWJ 67657, a p38 mitogen activated protein kinase (MAPK) inhibitor, on the production of inflammatory mediators by rheumatoid synovial fibroblasts
-
Westra J., Limburg P.C., de Boer P., and van Rijswijk M.H. Effects of RWJ 67657, a p38 mitogen activated protein kinase (MAPK) inhibitor, on the production of inflammatory mediators by rheumatoid synovial fibroblasts. Ann. Rheum. Dis. 63 (2004) 1453-1459
-
(2004)
Ann. Rheum. Dis.
, vol.63
, pp. 1453-1459
-
-
Westra, J.1
Limburg, P.C.2
de Boer, P.3
van Rijswijk, M.H.4
-
197
-
-
0025212710
-
Postinduction turnoff of beta-interferon gene expression
-
Whittemore L.-A., and Maniatis T. Postinduction turnoff of beta-interferon gene expression. Mol. Cell. Biol. 64 (1990) 1329-1337
-
(1990)
Mol. Cell. Biol.
, vol.64
, pp. 1329-1337
-
-
Whittemore, L.-A.1
Maniatis, T.2
-
199
-
-
0033230617
-
PKR; a sentinel kinase for cellular stress
-
Williams B.R. PKR; a sentinel kinase for cellular stress. Oncogene 18 (1999) 6112-6120
-
(1999)
Oncogene
, vol.18
, pp. 6112-6120
-
-
Williams, B.R.1
-
200
-
-
0346103717
-
Signal transducer and activator of transcription 3 is the dominant mediator of the anti-inflammatory effects of IL-10 in human macrophages
-
Williams L., Bradley L., Smith A., and Foxwell B. Signal transducer and activator of transcription 3 is the dominant mediator of the anti-inflammatory effects of IL-10 in human macrophages. J. Immunol. 172 (2004) 567-576
-
(2004)
J. Immunol.
, vol.172
, pp. 567-576
-
-
Williams, L.1
Bradley, L.2
Smith, A.3
Foxwell, B.4
-
201
-
-
8144226985
-
Interleukin-10 suppression of myeloid cell activation-a continuing puzzle
-
Williams L.M., Ricchetti G., Sarma U., Smallie T., and Foxwell B.M. Interleukin-10 suppression of myeloid cell activation-a continuing puzzle. Immunology 113 (2004) 281-292
-
(2004)
Immunology
, vol.113
, pp. 281-292
-
-
Williams, L.M.1
Ricchetti, G.2
Sarma, U.3
Smallie, T.4
Foxwell, B.M.5
-
202
-
-
2442647813
-
Distinct domains of AU-rich elements exert different functions in mRNA destabilization and stabilization by p38 mitogen-activated protein kinase or HuR
-
Winzen R., Gowrishankar G., Bollig F., Redich N., Resch K., and Holtmann H. Distinct domains of AU-rich elements exert different functions in mRNA destabilization and stabilization by p38 mitogen-activated protein kinase or HuR. Mol. Cell. Biol. 24 (2004) 4835-4847
-
(2004)
Mol. Cell. Biol.
, vol.24
, pp. 4835-4847
-
-
Winzen, R.1
Gowrishankar, G.2
Bollig, F.3
Redich, N.4
Resch, K.5
Holtmann, H.6
-
203
-
-
0033568608
-
The p38 MAP kinase pathway signals for cytokine-induced mRNA stabilization via MAP kinase-activated protein kinase 2 and an AU-rich region-targeted mechanism
-
Winzen R., Kracht M., Ritter B., Wilhelm A., Chen C.Y., Shyu A.B., Muller M., Gaestel M., Resch K., and Holtmann H. The p38 MAP kinase pathway signals for cytokine-induced mRNA stabilization via MAP kinase-activated protein kinase 2 and an AU-rich region-targeted mechanism. EMBO J. 18 (1999) 4969-4980
-
(1999)
EMBO J.
, vol.18
, pp. 4969-4980
-
-
Winzen, R.1
Kracht, M.2
Ritter, B.3
Wilhelm, A.4
Chen, C.Y.5
Shyu, A.B.6
Muller, M.7
Gaestel, M.8
Resch, K.9
Holtmann, H.10
-
204
-
-
0035423403
-
Essential role of neutrophils in the initiation and progression of a murine model of rheumatoid arthritis
-
Wipke B.T., and Allen P.M. Essential role of neutrophils in the initiation and progression of a murine model of rheumatoid arthritis. J. Immunol. 167 (2001) 1601-1608
-
(2001)
J. Immunol.
, vol.167
, pp. 1601-1608
-
-
Wipke, B.T.1
Allen, P.M.2
-
205
-
-
0025177186
-
Regulation of interleukin 3 mRNA expression in mast cells occurs at the posttranscriptional level and is mediated by calcium ions
-
Wodnar-Filipowicz A., and Moroni C. Regulation of interleukin 3 mRNA expression in mast cells occurs at the posttranscriptional level and is mediated by calcium ions. Proc. Natl. Acad. Sci. USA 87 (1990) 777-781
-
(1990)
Proc. Natl. Acad. Sci. USA
, vol.87
, pp. 777-781
-
-
Wodnar-Filipowicz, A.1
Moroni, C.2
-
206
-
-
0037073701
-
RNA Binding Properties of the AU-rich Element-binding Recombinant Nup475/TIS11/Tristetraprolin Protein
-
Worthington M.T., Pelo J.W., Sachedina M.A., Applegate J.L., Arseneau K.O., and Pizarro T.T. RNA Binding Properties of the AU-rich Element-binding Recombinant Nup475/TIS11/Tristetraprolin Protein. J. Biol. Chem. 277 (2002) 48558-48564
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 48558-48564
-
-
Worthington, M.T.1
Pelo, J.W.2
Sachedina, M.A.3
Applegate, J.L.4
Arseneau, K.O.5
Pizarro, T.T.6
-
207
-
-
0034806974
-
Versatile role for hnRNP D isoforms in the differential regulation of cytoplasmic mRNA turnover
-
Xu N., Chen C.Y., and Shyu A.B. Versatile role for hnRNP D isoforms in the differential regulation of cytoplasmic mRNA turnover. Mol. Cell. Biol. 21 (2001) 6960-6971
-
(2001)
Mol. Cell. Biol.
, vol.21
, pp. 6960-6971
-
-
Xu, N.1
Chen, C.Y.2
Shyu, A.B.3
-
208
-
-
0028609042
-
Regulation of interleukin (IL)-11 gene expression in IL-1 induced primate bone marrow stromal cells
-
Yang L., and Yang Y.C. Regulation of interleukin (IL)-11 gene expression in IL-1 induced primate bone marrow stromal cells. J. Biol. Chem. 269 (1994) 32732-32739
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 32732-32739
-
-
Yang, L.1
Yang, Y.C.2
-
209
-
-
0035154448
-
Dependence of interleukin-1-induced arthritis on granulocyte-macrophage colony-stimulating factor
-
Yang Y.H., and Hamilton J.A. Dependence of interleukin-1-induced arthritis on granulocyte-macrophage colony-stimulating factor. Arthritis Rheum. 44 (2001) 111-119
-
(2001)
Arthritis Rheum.
, vol.44
, pp. 111-119
-
-
Yang, Y.H.1
Hamilton, J.A.2
-
210
-
-
0037449716
-
Translational repression of human matrix metalloproteinases-13 by an alternatively spliced form of T-cell-restricted intracellular antigen-related protein (TIAR)
-
Yu Q., Cok S.J., Zeng C., and Morrison A.R. Translational repression of human matrix metalloproteinases-13 by an alternatively spliced form of T-cell-restricted intracellular antigen-related protein (TIAR). J. Biol. Chem. 278 (2003) 1579-1584
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 1579-1584
-
-
Yu, Q.1
Cok, S.J.2
Zeng, C.3
Morrison, A.R.4
-
211
-
-
0027496464
-
Purification, characterization, and cDNA cloning of an AU-rich element RNA-binding protein, AUF1
-
Zhang W., Wagner B.J., Ehrenman K., Schaefer A.W., De Maria C.T., Crater D., De Haven K., Long L., and Brewer G. Purification, characterization, and cDNA cloning of an AU-rich element RNA-binding protein, AUF1. Mol. Cell. Biol. 13 (1993) 7652-7665
-
(1993)
Mol. Cell. Biol.
, vol.13
, pp. 7652-7665
-
-
Zhang, W.1
Wagner, B.J.2
Ehrenman, K.3
Schaefer, A.W.4
De Maria, C.T.5
Crater, D.6
De Haven, K.7
Long, L.8
Brewer, G.9
-
212
-
-
0034885141
-
Gene suppression by tristetraprolin and release by the p38 pathway
-
Zhu W., Brauchle M.A., Di Padova F., Gram H., New L., Ono K., Downey J.S., and Han J. Gene suppression by tristetraprolin and release by the p38 pathway. Am. J. Lung Cell Mol. Physiol. 281 (2001) L499-L508
-
(2001)
Am. J. Lung Cell Mol. Physiol.
, vol.281
-
-
Zhu, W.1
Brauchle, M.A.2
Di Padova, F.3
Gram, H.4
New, L.5
Ono, K.6
Downey, J.S.7
Han, J.8
-
213
-
-
0028900073
-
The nonamer UUAUUUAUU is the key AU-rich sequence motif that mediates mRNA degradation
-
Zubiaga A.M., Belasco J.G., and Greenberg M.E. The nonamer UUAUUUAUU is the key AU-rich sequence motif that mediates mRNA degradation. Mol. Cell. Biol. 15 (1995) 2219-2230
-
(1995)
Mol. Cell. Biol.
, vol.15
, pp. 2219-2230
-
-
Zubiaga, A.M.1
Belasco, J.G.2
Greenberg, M.E.3
|