메뉴 건너뛰기




Volumn 105, Issue 1, 2005, Pages 282-288

Stabilization of IFN-γ mRNA by MAPK p38 in IL-12- and IL-18-stimulated human NK cells

Author keywords

[No Author keywords available]

Indexed keywords

4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; CD56 ANTIGEN; GAMMA INTERFERON; INTERLEUKIN 12; INTERLEUKIN 18; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE P38;

EID: 11144244014     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood-2004-07-2782     Document Type: Article
Times cited : (99)

References (70)
  • 1
    • 0028071932 scopus 로고
    • Macrophage activation and innate resistance to infection in SCID mice
    • Bancroft GJ, Kelly JP. Macrophage activation and innate resistance to infection in SCID mice. Immunobiology. 1994;191:424-431.
    • (1994) Immunobiology , vol.191 , pp. 424-431
    • Bancroft, G.J.1    Kelly, J.P.2
  • 3
    • 0037105590 scopus 로고    scopus 로고
    • Innate immune response to malaria: Rapid induction of IFN-gamma from human NK cells by live Plasmodium falciparum-infected erythrocytes
    • Artavanis-Tsakonas K, Riley EM. Innate immune response to malaria: rapid induction of IFN-gamma from human NK cells by live Plasmodium falciparum-infected erythrocytes. J Immunol. 2002;169:2956-2963.
    • (2002) J Immunol , vol.169 , pp. 2956-2963
    • Artavanis-Tsakonas, K.1    Riley, E.M.2
  • 4
    • 0030025945 scopus 로고    scopus 로고
    • Regulation of Trypanosoma cruzi infection in mice by gamma Interferon and interleukin 10: Role of NK cells
    • Cardillo F, Voltarelli JC, Reed SG, Silva JS. Regulation of Trypanosoma cruzi infection in mice by gamma Interferon and interleukin 10: role of NK cells. Infect Immun. 1996;64:128-134.
    • (1996) Infect Immun , vol.64 , pp. 128-134
    • Cardillo, F.1    Voltarelli, J.C.2    Reed, S.G.3    Silva, J.S.4
  • 6
    • 0842266786 scopus 로고    scopus 로고
    • Interferon-gamma: An overview of signals, mechanisms and functions
    • Schroder K, Hertzog PJ, Ravasi T, Hume DA. Interferon-gamma: an overview of signals, mechanisms and functions. J Leukoc Biol. 2004;75:163-189.
    • (2004) J Leukoc Biol , vol.75 , pp. 163-189
    • Schroder, K.1    Hertzog, P.J.2    Ravasi, T.3    Hume, D.A.4
  • 7
    • 0024957277 scopus 로고
    • Inflammatory destruction of pancreatic beta cells in gamma-interteron transgenic mice
    • Sarvetnick N, Shizuru J, Liggitt D, Stewart T. Inflammatory destruction of pancreatic beta cells in gamma-interteron transgenic mice. Cold Spring Harb Symp Quant Biol. 1989;54(pt 2):837-842.
    • (1989) Cold Spring Harb Symp Quant Biol , vol.54 , Issue.PART 2 , pp. 837-842
    • Sarvetnick, N.1    Shizuru, J.2    Liggitt, D.3    Stewart, T.4
  • 8
    • 0034663047 scopus 로고    scopus 로고
    • Coadministration of interleukin-18 and interleukin-12 induces a fatal inflammatory response in mice: Critical role of natural killer cell interferon-gamma production and STAT-mediated signal transduction
    • Carson WE, Dierksheide JE, Jabbour S, et al. Coadministration of interleukin-18 and interleukin-12 induces a fatal inflammatory response in mice: critical role of natural killer cell interferon-gamma production and STAT-mediated signal transduction. Blood. 2000;96:1465-1473.
    • (2000) Blood , vol.96 , pp. 1465-1473
    • Carson, W.E.1    Dierksheide, J.E.2    Jabbour, S.3
  • 9
    • 0036772485 scopus 로고    scopus 로고
    • Contribution of CD8+ T cells to innate immunity: IFN-gamma secretion induced by IL-12 and IL-18
    • Berg RE, Cordes CJ, Forman J. Contribution of CD8+ T cells to innate immunity: IFN-gamma secretion induced by IL-12 and IL-18. Eur J Immunol. 2002;32:2807-2816.
    • (2002) Eur J Immunol , vol.32 , pp. 2807-2816
    • Berg, R.E.1    Cordes, C.J.2    Forman, J.3
  • 12
    • 0035949237 scopus 로고    scopus 로고
    • Cytokine expression by murine DX5+ cells in response to IL-12, IL-18, or the combination of IL-12 and IL-18
    • Chakir H, Lemay AM, Webb JR. Cytokine expression by murine DX5+ cells in response to IL-12, IL-18, or the combination of IL-12 and IL-18. Cell Immunol. 2001;212:71-81.
    • (2001) Cell Immunol , vol.212 , pp. 71-81
    • Chakir, H.1    Lemay, A.M.2    Webb, J.R.3
  • 13
    • 0036932388 scopus 로고    scopus 로고
    • Regulatory pathways involved in the infection-induced production of IFN-gamma by NK cells
    • Lieberman LA, Hunter CA. Regulatory pathways involved in the infection-induced production of IFN-gamma by NK cells. Microbes Infect. 2002;4: 1531-1538.
    • (2002) Microbes Infect , vol.4 , pp. 1531-1538
    • Lieberman, L.A.1    Hunter, C.A.2
  • 15
    • 0037428675 scopus 로고    scopus 로고
    • Natural killer, but not natural killer T, cells play a necessary role in the promotion of an innate antitumor response induced by IL-18
    • Hashimoto W, Tanaka F, Robbins PD, et al. Natural killer, but not natural killer T, cells play a necessary role in the promotion of an innate antitumor response induced by IL-18. Int J Cancer. 2003;103:508-513.
    • (2003) Int J Cancer , vol.103 , pp. 508-513
    • Hashimoto, W.1    Tanaka, F.2    Robbins, P.D.3
  • 16
    • 0033084021 scopus 로고    scopus 로고
    • IL-18 up-regulates perforin-mediated Nκ activity without increasing perform messenger RNA expression by binding to constitutively expressed IL-18 receptor
    • Hyodo Y, Matsui K, Hayashi N, et al. IL-18 up-regulates perforin-mediated Nκ activity without increasing perform messenger RNA expression by binding to constitutively expressed IL-18 receptor. J Immunol. 1999;162:1662-1668.
    • (1999) J Immunol , vol.162 , pp. 1662-1668
    • Hyodo, Y.1    Matsui, K.2    Hayashi, N.3
  • 17
    • 0033970867 scopus 로고    scopus 로고
    • Synergistic effects of IL-4 and IL-18 on IL-12-dependent IFN- gamma production by dendritic cells
    • Fukao T, Matsuda S, Koyasu S. Synergistic effects of IL-4 and IL-18 on IL-12-dependent IFN- gamma production by dendritic cells. J Immunol. 2000;164:64-71.
    • (2000) J Immunol , vol.164 , pp. 64-71
    • Fukao, T.1    Matsuda, S.2    Koyasu, S.3
  • 18
    • 0035284905 scopus 로고    scopus 로고
    • The production of IFN-gamma by IL-12/IL-18-activated macrophages requires STAT4 signaling and is inhibited by IL-4
    • Schindler H, Lutz MB, Rollinghoff M, Bogdan C. The production of IFN-gamma by IL-12/IL-18-activated macrophages requires STAT4 signaling and is inhibited by IL-4. J Immunol. 2001;166: 3075-3082.
    • (2001) J Immunol , vol.166 , pp. 3075-3082
    • Schindler, H.1    Lutz, M.B.2    Rollinghoff, M.3    Bogdan, C.4
  • 19
    • 0032526840 scopus 로고    scopus 로고
    • Murine macrophages secrete interferon gamma upon combined stimulation with interleukin (IL)-12 and IL-18: A novel pathway of autocrine macrophage activation
    • Munder M, Mallo M, Eichmann K, Modolell M. Murine macrophages secrete interferon gamma upon combined stimulation with interleukin (IL)-12 and IL-18: a novel pathway of autocrine macrophage activation. J Exp Med. 1998;187: 2103-2108.
    • (1998) J Exp Med , vol.187 , pp. 2103-2108
    • Munder, M.1    Mallo, M.2    Eichmann, K.3    Modolell, M.4
  • 20
    • 0032193770 scopus 로고    scopus 로고
    • IL-12 up-regulates IL-18 receptor expression on T cells, Th1 cells, and B cells: Synergism with IL-18 for IFN-gamma production
    • Yoshimoto T, Takeda K, Tanaka T, et al. IL-12 up-regulates IL-18 receptor expression on T cells, Th1 cells, and B cells: synergism with IL-18 for IFN-gamma production. J Immunol. 1998;161: 3400-3407.
    • (1998) J Immunol , vol.161 , pp. 3400-3407
    • Yoshimoto, T.1    Takeda, K.2    Tanaka, T.3
  • 21
    • 0035261399 scopus 로고    scopus 로고
    • IL-18-stimulated GADD45 beta required in cytokine-induced, but not TCP-induced, IFN-gamma production
    • Yang J, Zhu H, Murphy TL, Ouyang W, Murphy KM. IL-18-stimulated GADD45 beta required in cytokine-induced, but not TCP-induced, IFN-gamma production. Nat Immunol. 2001;2:157-164.
    • (2001) Nat Immunol , vol.2 , pp. 157-164
    • Yang, J.1    Zhu, H.2    Murphy, T.L.3    Ouyang, W.4    Murphy, K.M.5
  • 22
    • 0344585412 scopus 로고    scopus 로고
    • Regulation and phenotype of an innate Th1 cell: Role of cytokines and the p38 kinase pathway
    • Yu JJ, Tripp CS, Russell JH. Regulation and phenotype of an innate Th1 cell: role of cytokines and the p38 kinase pathway. J Immunol. 2003;171: 6112-6118.
    • (2003) J Immunol , vol.171 , pp. 6112-6118
    • Yu, J.J.1    Tripp, C.S.2    Russell, J.H.3
  • 23
    • 0037929186 scopus 로고    scopus 로고
    • Defining the involvement of p38alpha MAPK in the production of anti- and proinflammatory cytokines using an SB 203580-resistant form of the kinase
    • Guo X, Gerl RE, Schrader JW. Defining the involvement of p38alpha MAPK in the production of anti- and proinflammatory cytokines using an SB 203580-resistant form of the kinase. J Biol Chem. 2003;278:22237-22242.
    • (2003) J Biol Chem , vol.278 , pp. 22237-22242
    • Guo, X.1    Gerl, R.E.2    Schrader, J.W.3
  • 24
    • 0033558986 scopus 로고    scopus 로고
    • A specific inhibitor of the p38 mitogen activated protein kinase affects differentially the production of various cytokines by activated human T cells: Dependence on CD28 signaling and preferential inhibition of IL-10 production
    • Koprak S, Staruch MJ, Dumont FJ. A specific inhibitor of the p38 mitogen activated protein kinase affects differentially the production of various cytokines by activated human T cells: dependence on CD28 signaling and preferential inhibition of IL-10 production. Cell Immunol. 1999;192:87-95.
    • (1999) Cell Immunol , vol.192 , pp. 87-95
    • Koprak, S.1    Staruch, M.J.2    Dumont, F.J.3
  • 25
    • 0032525233 scopus 로고    scopus 로고
    • Interferon-gamma expression by Th1 effector T cells mediated by the p38 MAP kinase signaling pathway
    • Rincon M, Enslen H, Raingeaud J, et al. Interferon-gamma expression by Th1 effector T cells mediated by the p38 MAP kinase signaling pathway. EMBO J. 1998;17:2817-2829.
    • (1998) EMBO J , vol.17 , pp. 2817-2829
    • Rincon, M.1    Enslen, H.2    Raingeaud, J.3
  • 26
    • 0035881573 scopus 로고    scopus 로고
    • Cutting edge: Induction of IFN-gamma production but not cytotoxicity by the killer cell Ig-like receptor KIR2DL4 (CD158d) in resting NK cells
    • Rajagopalan S, Fu J, Long EO. Cutting edge: induction of IFN-gamma production but not cytotoxicity by the killer cell Ig-like receptor KIR2DL4 (CD158d) in resting NK cells. J Immunol. 2001; 167:1877-1881.
    • (2001) J Immunol , vol.167 , pp. 1877-1881
    • Rajagopalan, S.1    Fu, J.2    Long, E.O.3
  • 27
    • 0035575998 scopus 로고    scopus 로고
    • 2B4 (CD244)-mediated activation of cytotoxicity and IFN-gamma release in human NK cells involves distinct pathways
    • Chuang SS, Kumaresan PR, Mathew PA. 2B4 (CD244)-mediated activation of cytotoxicity and IFN-gamma release in human NK cells involves distinct pathways. J Immunol. 2001;167:6210-6216.
    • (2001) J Immunol , vol.167 , pp. 6210-6216
    • Chuang, S.S.1    Kumaresan, P.R.2    Mathew, P.A.3
  • 28
    • 0033145354 scopus 로고    scopus 로고
    • MAPKAP kinase 2 is essential for LPS-induced TNF-alpha biosynthesis
    • Kotlyarov A, Neininger A, Schubert C, et al. MAPKAP kinase 2 is essential for LPS-induced TNF-alpha biosynthesis. Nat Cell Biol. 1999;1:94-97.
    • (1999) Nat Cell Biol , vol.1 , pp. 94-97
    • Kotlyarov, A.1    Neininger, A.2    Schubert, C.3
  • 29
    • 0036569435 scopus 로고    scopus 로고
    • Mitogen-activated protein kinase-activated protein kinase 2-deficient mice show increased susceptibility to Listeria monocytogenes infection
    • Lehner MD, Schwoebel F, Kotlyarov A, Leist M, Gaestel M, Hartung T. Mitogen-activated protein kinase-activated protein kinase 2-deficient mice show increased susceptibility to Listeria monocytogenes infection. J Immunol. 2002;168:4667-4673.
    • (2002) J Immunol , vol.168 , pp. 4667-4673
    • Lehner, M.D.1    Schwoebel, F.2    Kotlyarov, A.3    Leist, M.4    Gaestel, M.5    Hartung, T.6
  • 30
  • 31
    • 0026592604 scopus 로고
    • Mechanisms of IFN-gamma induction by natural killer cell stimulatory factor (NKSF/IL-12): Role of transcription and mRNA stability in the synergistic interaction between NKSF and IL-2
    • Chan SH, Kobayashi M, Santoli D, Perussia B, Trinchieri G. Mechanisms of IFN-gamma induction by natural killer cell stimulatory factor (NKSF/IL-12): role of transcription and mRNA stability in the synergistic interaction between NKSF and IL-2. J Immunol. 1992;148:92-98.
    • (1992) J Immunol , vol.148 , pp. 92-98
    • Chan, S.H.1    Kobayashi, M.2    Santoli, D.3    Perussia, B.4    Trinchieri, G.5
  • 32
    • 0029100898 scopus 로고
    • Cellular and molecular mechanisms of IFN-gamma production induced by IL-2 and IL-12 in a human NK cell line
    • Ye J, Ortaldo JR, Conlon K, Winkler-Pickett R, Young HA. Cellular and molecular mechanisms of IFN-gamma production induced by IL-2 and IL-12 in a human NK cell line. J Leukoc Biol. 1995;58: 225-233.
    • (1995) J Leukoc Biol , vol.58 , pp. 225-233
    • Ye, J.1    Ortaldo, J.R.2    Conlon, K.3    Winkler-Pickett, R.4    Young, H.A.5
  • 33
    • 0034077529 scopus 로고    scopus 로고
    • Regulation of cyclooxygenase 2 mRNA stability by the mitogen-activated protein kinase p38 signaling cascade
    • Lasa M, Mahtani KR, Finch A, Brewer G, Saklatvala J, Clark AR. Regulation of cyclooxygenase 2 mRNA stability by the mitogen-activated protein kinase p38 signaling cascade. Mol Cell Biol. 2000;20:4265-4274.
    • (2000) Mol Cell Biol , vol.20 , pp. 4265-4274
    • Lasa, M.1    Mahtani, K.R.2    Finch, A.3    Brewer, G.4    Saklatvala, J.5    Clark, A.R.6
  • 34
    • 0032518175 scopus 로고    scopus 로고
    • A broader role for AU-rich element-mediated mRNA turnover revealed by a new transcriptional pulse strategy
    • Xu N, Loflin P, Chen CY, Shyu AB. A broader role for AU-rich element-mediated mRNA turnover revealed by a new transcriptional pulse strategy. Nucleic Acids Res. 1998;26:558-565.
    • (1998) Nucleic Acids Res , vol.26 , pp. 558-565
    • Xu, N.1    Loflin, P.2    Chen, C.Y.3    Shyu, A.B.4
  • 35
    • 0034644837 scopus 로고    scopus 로고
    • Regulation of tumour necrosis factor alpha mRNA stability by the mitogen-activated protein kinase p38 signalling cascade
    • Brook M, Sully G, Clark AR, Saklatvala J. Regulation of tumour necrosis factor alpha mRNA stability by the mitogen-activated protein kinase p38 signalling cascade. FEBS Lett. 2000;483:57-61.
    • (2000) FEBS Lett , vol.483 , pp. 57-61
    • Brook, M.1    Sully, G.2    Clark, A.R.3    Saklatvala, J.4
  • 36
    • 0035138742 scopus 로고    scopus 로고
    • Dexamethasone destabilizes cyclooxygenase 2 mRNA by inhibiting mitogen-activated protein kinase p38
    • Lasa M, Brook M, Saklatvala J, Clark AR. Dexamethasone destabilizes cyclooxygenase 2 mRNA by inhibiting mitogen-activated protein kinase p38. Mol Cell Biol. 2001;21:771-780.
    • (2001) Mol Cell Biol , vol.21 , pp. 771-780
    • Lasa, M.1    Brook, M.2    Saklatvala, J.3    Clark, A.R.4
  • 37
    • 0242643740 scopus 로고    scopus 로고
    • IFN-gamma production in human NK cells through the engagement of CD8 by soluble or surface HLA class I molecules
    • Spaggiari GM, Contini P, Negrini S, et al. IFN-gamma production in human NK cells through the engagement of CD8 by soluble or surface HLA class I molecules. Eur J Immunol. 2003;33:3049-3059.
    • (2003) Eur J Immunol , vol.33 , pp. 3049-3059
    • Spaggiari, G.M.1    Contini, P.2    Negrini, S.3
  • 39
    • 3543003469 scopus 로고    scopus 로고
    • The stability of tristetraprolin mRNA is regulated by mitogen-activated protein kinase p38 and by tristetraprolin itself
    • Tchen CR, Brook M, Saklatvala J, Clark AR. The stability of tristetraprolin mRNA is regulated by mitogen-activated protein kinase p38 and by tristetraprolin itself. J Biol Chem. 2004;279:32393-32400.
    • (2004) J Biol Chem , vol.279 , pp. 32393-32400
    • Tchen, C.R.1    Brook, M.2    Saklatvala, J.3    Clark, A.R.4
  • 40
    • 0033568608 scopus 로고    scopus 로고
    • The p38 MAP kinase pathway signals for cytokine-induced mRNA stabilization via MAP kinase-activated protein kinase 2 and an AU-rich region-targeted mechanism
    • Winzen R, Kracht M, Ritter B, et al. The p38 MAP kinase pathway signals for cytokine-induced mRNA stabilization via MAP kinase-activated protein kinase 2 and an AU-rich region-targeted mechanism. EMBO J. 1999;18:4969-4980.
    • (1999) EMBO J , vol.18 , pp. 4969-4980
    • Winzen, R.1    Kracht, M.2    Ritter, B.3
  • 41
    • 0036435213 scopus 로고    scopus 로고
    • Transcriptional and post-transcriptional control of gene expression in inflammation
    • Kracht M, Saklatvala J. Transcriptional and post-transcriptional control of gene expression in inflammation. Cytokine. 2002;20:91-106.
    • (2002) Cytokine , vol.20 , pp. 91-106
    • Kracht, M.1    Saklatvala, J.2
  • 42
    • 0038538477 scopus 로고    scopus 로고
    • Post-transcriptional regulation of gene expression by mitogen-activated protein kinase p38
    • Clark AR, Dean JL, Saklatvala J. Post-transcriptional regulation of gene expression by mitogen-activated protein kinase p38. FEBS Lett. 2003; 546:37-44.
    • (2003) FEBS Lett , vol.546 , pp. 37-44
    • Clark, A.R.1    Dean, J.L.2    Saklatvala, J.3
  • 43
    • 0037223402 scopus 로고    scopus 로고
    • p38 mitogen-activated protein kinase-dependent and -independent signaling of mRNA stability of AU-rich element-containing transcripts
    • Frevel MA, Bakheet T, Silva AM, Hissong JG, Khabar KS, Williams BR. p38 Mitogen-activated protein kinase-dependent and -independent signaling of mRNA stability of AU-rich element-containing transcripts. Mol Cell Biol. 2003;23:425-436.
    • (2003) Mol Cell Biol , vol.23 , pp. 425-436
    • Frevel, M.A.1    Bakheet, T.2    Silva, A.M.3    Hissong, J.G.4    Khabar, K.S.5    Williams, B.R.6
  • 44
    • 0141960214 scopus 로고    scopus 로고
    • p38 mitogen-activated protein kinase stabilizes mRNAs that contain cyclooxygenase-2 and tumor necrosis factor AU-rich elements by inhibiting deadenylation
    • Dean JL, Sarsfield SJ, Tsounakou E, Saklatvala J. p38 Mitogen-activated protein kinase stabilizes mRNAs that contain cyclooxygenase-2 and tumor necrosis factor AU-rich elements by inhibiting deadenylation. J Biol Chem. 2003;278:39470-39476.
    • (2003) J Biol Chem , vol.278 , pp. 39470-39476
    • Dean, J.L.1    Sarsfield, S.J.2    Tsounakou, E.3    Saklatvala, J.4
  • 45
    • 0032951716 scopus 로고    scopus 로고
    • p38 mitogen-activated protein kinase regulates cyclooxygenase-2 mRNA stability and transcription in lipopolysaccharide-treated human monocytes
    • Dean JL, Brook M, Clark AR, Saklatvala J. p38 mitogen-activated protein kinase regulates cyclooxygenase-2 mRNA stability and transcription in lipopolysaccharide-treated human monocytes. J Biol Chem. 1999;274:264-269.
    • (1999) J Biol Chem , vol.274 , pp. 264-269
    • Dean, J.L.1    Brook, M.2    Clark, A.R.3    Saklatvala, J.4
  • 46
    • 0032544234 scopus 로고    scopus 로고
    • Regulation of interleukin-1 beta-induced interleukin-6 gene expression in human fibroblast-like synoviocytes by p38 mitogen-activated protein kinase
    • Miyazawa K, Mori A, Miyata H, Akahane M, Ajisawa Y, Okudaira H. Regulation of interleukin-1 beta-induced interleukin-6 gene expression in human fibroblast-like synoviocytes by p38 mitogen-activated protein kinase. J Biol Chem. 1998; 273:24832-24838.
    • (1998) J Biol Chem , vol.273 , pp. 24832-24838
    • Miyazawa, K.1    Mori, A.2    Miyata, H.3    Akahane, M.4    Ajisawa, Y.5    Okudaira, H.6
  • 47
    • 0032422182 scopus 로고    scopus 로고
    • Binding of interleukin-18 to the interleukin-1 receptor homologous receptor IL-1Rrp1 leads to activation of signaling pathways similar to those used by interleukin-1
    • Thomassen E, Bird TA, Renshaw BR, Kennedy MK, Sims JE. Binding of interleukin-18 to the interleukin-1 receptor homologous receptor IL-1Rrp1 leads to activation of signaling pathways similar to those used by interleukin-1. J Interferon Cytokine Res. 1998;18:1077-1088.
    • (1998) J Interferon Cytokine Res , vol.18 , pp. 1077-1088
    • Thomassen, E.1    Bird, T.A.2    Renshaw, B.R.3    Kennedy, M.K.4    Sims, J.E.5
  • 49
    • 0031230444 scopus 로고    scopus 로고
    • A mechanism underlying synergy between IL-12 and IFN-gamma-inducing factor in enhanced production of IFN-gamma
    • Ahn HJ, Maruo S, Tomura M, et al. A mechanism underlying synergy between IL-12 and IFN-gamma-inducing factor in enhanced production of IFN-gamma. J Immunol. 1997;159:2125-2131.
    • (1997) J Immunol , vol.159 , pp. 2125-2131
    • Ahn, H.J.1    Maruo, S.2    Tomura, M.3
  • 50
    • 0034284088 scopus 로고    scopus 로고
    • Importance of the MKK6/p38 pathway for interleukin-12-induced STAT4 serine phosphorylation and transcriptional activity
    • Visconti R, Gadina M, Chiariello M, et al. Importance of the MKK6/p38 pathway for interleukin-12-induced STAT4 serine phosphorylation and transcriptional activity. Blood. 2000;96:1844-1852.
    • (2000) Blood , vol.96 , pp. 1844-1852
    • Visconti, R.1    Gadina, M.2    Chiariello, M.3
  • 51
    • 0034254177 scopus 로고    scopus 로고
    • The p38 mitogen-activated protein kinase is required for IL-12-induced IFN-gamma expression
    • Zhang S, Kaplan MH. The p38 mitogen-activated protein kinase is required for IL-12-induced IFN-gamma expression. J Immunol. 2000;165:1374-1380.
    • (2000) J Immunol , vol.165 , pp. 1374-1380
    • Zhang, S.1    Kaplan, M.H.2
  • 52
    • 0034743912 scopus 로고    scopus 로고
    • GADD45gamma mediates the activation of the p38 and JNK MAP kinase pathways and cytokine production in effector TH1 cells
    • Lu B, Yu H, Chow C, et al. GADD45gamma mediates the activation of the p38 and JNK MAP kinase pathways and cytokine production in effector TH1 cells. Immunity. 2001;14:583-590.
    • (2001) Immunity , vol.14 , pp. 583-590
    • Lu, B.1    Yu, H.2    Chow, C.3
  • 53
    • 2342486760 scopus 로고    scopus 로고
    • GADD45beta/GADD45gamma and MEKK4 comprise a genetic pathway mediating STAT4-independent IFNgamma production in T cells
    • Chi H, Lu B, Takekawa M, Davis RJ, Flavell RA. GADD45beta/GADD45gamma and MEKK4 comprise a genetic pathway mediating STAT4-independent IFNgamma production in T cells. EMBO J. 2004;23:1576-1586.
    • (2004) EMBO J , vol.23 , pp. 1576-1586
    • Chi, H.1    Lu, B.2    Takekawa, M.3    Davis, R.J.4    Flavell, R.A.5
  • 54
    • 0032521933 scopus 로고    scopus 로고
    • IL-12 and IL-18 differentially regulate the transcriptional activity of the human IFN-gamma promoter in primary CD4+ T lymphocytes
    • Barbulescu K, Becker C, Schlaak JF, Schmitt E, Meyer zum Buschenfelde KH, Neurath MF. IL-12 and IL-18 differentially regulate the transcriptional activity of the human IFN-gamma promoter in primary CD4+ T lymphocytes. J Immunol. 1998; 160:3642-3647.
    • (1998) J Immunol , vol.160 , pp. 3642-3647
    • Barbulescu, K.1    Becker, C.2    Schlaak, J.F.3    Schmitt, E.4    Meyer Zum Buschenfelde, K.H.5    Neurath, M.F.6
  • 55
    • 0036467440 scopus 로고    scopus 로고
    • Synergy of IL-12 and IL-18 for IFN-gamma gene expression: IL-12-induced STAT4 contributes to IFN-gamma promoter activation by up-regulating the binding activity of IL-18-induced activator protein 1
    • Nakahira M, Ahn HJ, Park WR, et al. Synergy of IL-12 and IL-18 for IFN-gamma gene expression: IL-12-induced STAT4 contributes to IFN-gamma promoter activation by up-regulating the binding activity of IL-18-induced activator protein 1. J Immunol. 2002;168:1146-1153.
    • (2002) J Immunol , vol.168 , pp. 1146-1153
    • Nakahira, M.1    Ahn, H.J.2    Park, W.R.3
  • 56
    • 15844396183 scopus 로고    scopus 로고
    • Requirement for Stat4 in interleukin-12-mediated responses of natural killer and T cells
    • Thierfelder WE, van Deursen JM, Yamamoto K, et al. Requirement for Stat4 in interleukin-12-mediated responses of natural killer and T cells. Nature. 1996;382:171-174.
    • (1996) Nature , vol.382 , pp. 171-174
    • Thierfelder, W.E.1    Van Deursen, J.M.2    Yamamoto, K.3
  • 57
    • 0034046605 scopus 로고    scopus 로고
    • STAT family of transcription factors in cytokine-mediated biological responses
    • Takeda K, Akira S. STAT family of transcription factors in cytokine-mediated biological responses. Cytokine Growth Factor Rev. 2000;11: 199-207.
    • (2000) Cytokine Growth Factor Rev , vol.11 , pp. 199-207
    • Takeda, K.1    Akira, S.2
  • 58
    • 0037514399 scopus 로고    scopus 로고
    • IL-21 in synergy with IL-15 or IL-18 enhances IFN-gamma production in human NK and T cells
    • Strengell M, Matikainen S, Siren J, et al. IL-21 in synergy with IL-15 or IL-18 enhances IFN-gamma production in human NK and T cells. J Immunol. 2003;170:5464-5469.
    • (2003) J Immunol , vol.170 , pp. 5464-5469
    • Strengell, M.1    Matikainen, S.2    Siren, J.3
  • 59
    • 0037125988 scopus 로고    scopus 로고
    • STAT4 serine phosphorylation is critical for IL-12-induced IFN-gamma production but not for cell proliferation
    • Morinobu A, Gadina M, Strober W, et al. STAT4 serine phosphorylation is critical for IL-12-induced IFN-gamma production but not for cell proliferation. Proc Natl Acad Sci USA. 2002;99: 12281-12286.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 12281-12286
    • Morinobu, A.1    Gadina, M.2    Strober, W.3
  • 60
    • 3242771189 scopus 로고    scopus 로고
    • Cutting edge: Innate production of IFN-gamma by NK cells is independent of epigenetic modification of the IFN-gamma promoter
    • Tato CM, Martins GA, High FA, DiCioccio CB, Reiner SL, Hunter CA. Cutting edge: innate production of IFN-gamma by NK cells is independent of epigenetic modification of the IFN-gamma promoter. J Immunol. 2004;173:1514-1517.
    • (2004) J Immunol , vol.173 , pp. 1514-1517
    • Tato, C.M.1    Martins, G.A.2    High, F.A.3    DiCioccio, C.B.4    Reiner, S.L.5    Hunter, C.A.6
  • 61
    • 0141924778 scopus 로고    scopus 로고
    • Constitutive cytokine mRNAs mark natural killer (NK) and NKT cells poised for rapid effector function
    • Stetson DB, Mohrs M, Reinhardt RU, et al. Constitutive cytokine mRNAs mark natural killer (NK) and NKT cells poised for rapid effector function. J Exp Med. 2003;198:1069-1076.
    • (2003) J Exp Med , vol.198 , pp. 1069-1076
    • Stetson, D.B.1    Mohrs, M.2    Reinhardt, R.U.3
  • 62
    • 0032794651 scopus 로고    scopus 로고
    • The mechanism of activation of NK-cell IFN-gamma production by ligation of CD28
    • Cheung JC, Koh CY, Gordon BE, Wilder JA, Yuan D. The mechanism of activation of NK-cell IFN-gamma production by ligation of CD28. Mol Immunol. 1999;36:361-372.
    • (1999) Mol Immunol , vol.36 , pp. 361-372
    • Cheung, J.C.1    Koh, C.Y.2    Gordon, B.E.3    Wilder, J.A.4    Yuan, D.5
  • 63
    • 1642463417 scopus 로고    scopus 로고
    • Analysis of protein phosphorylation and cellular signaling events by flow cytometry: Techniques and clinical applications
    • Krutzik PO, Irish JM, Nolan GP, Perez OD. Analysis of protein phosphorylation and cellular signaling events by flow cytometry: techniques and clinical applications. Clin Immunol. 2004;110:206-221.
    • (2004) Clin Immunol , vol.110 , pp. 206-221
    • Krutzik, P.O.1    Irish, J.M.2    Nolan, G.P.3    Perez, O.D.4
  • 64
    • 0033561762 scopus 로고    scopus 로고
    • Differential cytokine and chemokine gene expression by human NK cells following activation with IL-18 or IL-15 in combination with IL-12: Implications for the innate immune response
    • Fehniger TA, Shah MH, Turner MJ, et al. Differential cytokine and chemokine gene expression by human NK cells following activation with IL-18 or IL-15 in combination with IL-12: implications for the innate immune response. J Immunol. 1999; 162:4511-4520.
    • (1999) J Immunol , vol.162 , pp. 4511-4520
    • Fehniger, T.A.1    Shah, M.H.2    Turner, M.J.3
  • 65
    • 0035874522 scopus 로고    scopus 로고
    • Human natural killer cells: A unique innate immuno-regulatory role for the CD56(bright) subset
    • Cooper MA, Fehniger TA, Turner SC, et al. Human natural killer cells: a unique innate immuno-regulatory role for the CD56(bright) subset. Blood. 2001;97:3146-3151.
    • (2001) Blood , vol.97 , pp. 3146-3151
    • Cooper, M.A.1    Fehniger, T.A.2    Turner, S.C.3
  • 66
    • 0034740653 scopus 로고    scopus 로고
    • CD56bright cells differ in their KIR repertoire and cytotoxic features from CD56dim NK cells
    • Jacobs R, Hintzen G, Kemper A, et al. CD56bright cells differ in their KIR repertoire and cytotoxic features from CD56dim NK cells: Eur J Immunol. 2001;31:3121-3127.
    • (2001) Eur J Immunol , vol.31 , pp. 3121-3127
    • Jacobs, R.1    Hintzen, G.2    Kemper, A.3
  • 67
    • 0035863737 scopus 로고    scopus 로고
    • Bystander activation of CD8+ T cells contributes to the rapid production of IFN-gamma in response to bacterial pathogens
    • Lertmemongkolchai G, Cai G, Hunter CA, Bancroft GJ. Bystander activation of CD8+ T cells contributes to the rapid production of IFN-gamma in response to bacterial pathogens. J Immunol. 2001;166:1097-1105.
    • (2001) J Immunol , vol.166 , pp. 1097-1105
    • Lertmemongkolchai, G.1    Cai, G.2    Hunter, C.A.3    Bancroft, G.J.4
  • 68
    • 0035862335 scopus 로고    scopus 로고
    • Misregulated posttranscriptional checkpoints: Inflammation and tumorigenesis
    • Brewer G. Misregulated posttranscriptional checkpoints: inflammation and tumorigenesis. J Exp Med. 2001;193:F1-F4.
    • (2001) J Exp Med , vol.193
    • Brewer, G.1
  • 69
    • 0034016053 scopus 로고    scopus 로고
    • Polymorphisms of the human IFNG gene noncoding regions
    • Bream JH, Carrington M, O'Toole S, et al. Polymorphisms of the human IFNG gene noncoding regions. Immunogenetics. 2000;51:50-58.
    • (2000) Immunogenetics , vol.51 , pp. 50-58
    • Bream, J.H.1    Carrington, M.2    O'Toole, S.3
  • 70
    • 0036482349 scopus 로고    scopus 로고
    • Description of three new polymorphisms in the intronic and 3'UTR regions of the human interferon gamma gene
    • Henri S, Stefani F, Parzy D, Eboumbou C, Dessein A, Chevillard C. Description of three new polymorphisms in the intronic and 3'UTR regions of the human interferon gamma gene. Genes Immun. 2002;3:1-4.
    • (2002) Genes Immun , vol.3 , pp. 1-4
    • Henri, S.1    Stefani, F.2    Parzy, D.3    Eboumbou, C.4    Dessein, A.5    Chevillard, C.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.