TIA-1 regulates the production of tumor necrosis factor α in macrophages, but not in lymphocytes

Arthritis and Rheumatism

Volumn 44, Issue 12, 2001, Pages 2879-2887

  Saito, Keiko ^a   Chen, Samantha ^a   Piecyk, Monica ^a   Anderson, Paul ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CONCANAVALIN A; IONOMYCIN; LIPOPOLYSACCHARIDE; PHORBOL 13 ACETATE 12 MYRISTATE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG TARGETING; IMMUNOBLOTTING; LYMPHOCYTE; MACROPHAGE; MOUSE; NONHUMAN; PERITONEUM MACROPHAGE; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY MECHANISM; SPLEEN CELL; T LYMPHOCYTE;

ANIMALS; ANTIBODIES; ANTIGENS, CD28; ANTIGENS, CD3; CARCINOGENS; CONCANAVALIN A; FEMALE; FLOW CYTOMETRY; IONOMYCIN; IONOPHORES; LIPOPOLYSACCHARIDES; MACROPHAGES; MALE; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; MICE, MUTANT STRAINS; PROTEINS; RNA-BINDING PROTEINS; T-LYMPHOCYTES; TETRADECANOYLPHORBOL ACETATE; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0035677246     PISSN: 00043591     EISSN: None     Source Type: Journal    
DOI: 10.1002/1529-0131(200112)44:12<2879::AID-ART476>3.0.CO;2-4     Document Type: Article

References (38)

1. The role of tumor necrosis factor in health and disease
2. The role of cytokines in the pathogenesis of rheumatoid arthritis
3. The function of tumor necrosis factor and receptors in models of multi-organ inflammation, rheumatoid arthritis, multiple scleroisis and inflammatory bowel disease
4. The mechanisms of action of disease-modifying antirheumatic drugs: A review with emphasis on macrophage signal transduction and the induction of proinflammatory cytokines
5. Localization of tumor necrosis factor α in synovial tissues and at the cartilage-pannus junction in patients with rheumatoid arthritis
6. Quantitative analysis of cytokine gene expression in rheumatoid arthritis
7. Regulation of interleukin-1β-induced interleukin-6 gene expression in human fibroblast-like synoviocytes by p38 mitogen-activated protein kinase
8. Detection of tumor necrosis factor α but not tumor necrosis factor β in rheumatoid arthritis synovial fluid and serum
9. Randomised double-blind comparison of chimeric monoclonal antibody to tumour necrosis factor alpha (cA2) versus placebo in rheumatoid arthritis
10. Therapeutic efficacy of multiple intravenous infusions of anti-tumor necrosis factor α monoclonal antibody combined with low-dose weekly methotrexate in rheumatoid arthritis
11. Treatment of rheumatoid arthritis with a recombinant human tumor necrosis factor receptor (p75)-Fc fusion protein
12. Etanercept therapy in rheumatoid arthritis: A randomized, controlled trial
13. Endotoxin-responsive sequences control cachectin/tumor necrosis factor biosynthesis at the translational level
14. The essential role of the UA-rich sequence in endotoxin-induced cachectin/TNF synthesis
15. Posttranscriptional regulation of protein expression in human epithelial carcinoma cells by adenine-uridine-rich elements in the 3′-untranslated region of tumor necrosis factor-α messenger RNA
16. Identification of a common nucleotide sequence in the 3′-untranslated region of mRNA molecules specifying inflammatory mediators
17. Translational blockade imposed by cytokine-derived UA-rich sequences
18. Mapping of a minimal AU-rich sequence required for lipopolysaccharide-induced binding of a 55-kDa protein on tumor necrosis factor-α mRNA
19. Impaired on/off regulation of TNF biosynthesis in mice lacking TNF AU-rich elements: Implications for joint and gut-associated immunopathologies
20. Feedback inhibition of macrophage tumor necrosis factor α production by tristetraprolin
21. Evidence that tristetraprolin binds to AU-rich elements and promotes the deadenylation and destabilization of tumor necrosis factor alpha mRNA
22. A pathogenetic role for TNFα in the syndrome of cachexia, arthritis, and autoimmunity resulting from tristetraprolin (TTP) deficiency
23. Overexpression of HuR, a nuclear-cytoplasmic shuttling protein, increases the in vivo stability of ARE-containing mRNAs
24. Identification of HuR as a protein implicated in AUUUA-mediated mRNA decay
25. RNA stabilization by the AU-rich element binding protein, HuR, an ELAV protein
26. The inhibitory activity of the AU-rich RNA element in the human papillomavirus type 1 late 3′ untranslated region correlates with its affinity for the elav-like HuR protein
27. RNA-binding protein TIAR is essential for primordial germ cell development
28. Individual RNA recognition motifs of TIA-1 and TIAR have different RNA binding specificities
29. Identification and functional characterization of a TIA-1-related nucleolysin
30. TIA-1 is a translational silencer that selectively regulates the expression of TNF-alpha
31. A polyadenylate binding protein localized to the granules of cytolytic lymphocytes induces DNA fragmentation in target cells
32. Human host response to Mycobacterium tuberculosis
33. Functions of T-cell subsets and cytokines in mycobacterial infections
34. Cytokines in mycobacterial infections: In vitro and ex vivo studies
35. Identification of TIAR as a protein binding to the translational regulatory AU-rich element of tumor necrosis factor α mRNA
36. Patterns of cytokine production by mycobacterium-reactive human T-cell clones
37. Role of cytokines in tuberculosis
38. Host defense against nontuberculous mycobacterial infections