Genetic dissection of the cellular pathways and signaling mechanisms in modeled tumor necrosis factor-induced Crohn's-like inflammatory bowel disease

Journal of Experimental Medicine

Volumn 196, Issue 12, 2002, Pages 1563-1574

  Kontoyiannis, Dimitris ^a   Boulougouris, George ^a   Manoloukos, Menelaos ^a   Armaka, Maria ^a   Apostolaki, Maria ^a   Pizarro, Theresa ^b   Kotlyarov, Alexey ^c   Forster, Irmgard ^d   Flavell, Richard ^e   Gaestel, Matthias ^c   Tsichlis, Philip ^f   Cominelli, Fabio ^b   Kollias, George ^a  

^a BIOMEDICAL SCIENCES RESEARCH CENTER ALEXANDER FLEMING   (Greece)

^b UNIVERSITY OF VIRGINIA HEALTH SYSTEM   (United States)

^c HANNOVER MEDICAL SCHOOL   (Germany)

^d TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^e YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^f TUFTS MEDICAL CENTER   (United States)

Author keywords

Apoptosis; CD8+ lymphocytes; Intestine; MAPK SAPK; Targeted mutants

Indexed keywords

CRE RECOMBINASE; GAMMA INTERFERON; INTERLEUKIN 12; MITOGEN ACTIVATED PROTEIN KINASE 1; MUTANT PROTEIN; PHOSPHOTRANSFERASE; STRESS ACTIVATED PROTEIN KINASE; TUMOR NECROSIS FACTOR; TUMOR NECROSIS FACTOR RECEPTOR;

ALLELE; ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATTENUATION; BONE MARROW CELL; BONE MARROW TRANSPLANTATION; CONTROLLED STUDY; CROHN DISEASE; DISEASE COURSE; DISEASE EXACERBATION; DISEASE MODEL; ENTERITIS; FEMALE; GENE ACTIVATION; GENETIC RECOMBINATION; MOUSE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; STROMA CELL; T LYMPHOCYTE; TARGET CELL; TISSUE SPECIFICITY;

ANIMALS; APOPTOSIS; BONE MARROW TRANSPLANTATION; CROHN DISEASE; DISEASE MODELS, ANIMAL; FEMALE; FLOW CYTOMETRY; HUMANS; ILEUM; IN SITU NICK-END LABELING; MICE; MICE, INBRED BALB C; MICE, TRANSGENIC; MITOGEN-ACTIVATED PROTEIN KINASES; RECEPTORS, TUMOR NECROSIS FACTOR; SIGNAL TRANSDUCTION; SPLEEN; T-LYMPHOCYTE SUBSETS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0037121941     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.20020281     Document Type: Article

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