메뉴 건너뛰기




Volumn 113, Issue 3, 2004, Pages 281-292

Interleukin-10 suppression of myeloid cell activation - A continuing puzzle

Author keywords

Cytokines interleukins; Inflammation inflammatory mediators including eicosanoids; Signalling signal transduction

Indexed keywords

INTERLEUKIN 10; JANUS KINASE; JANUS KINASE 1; STAT3 PROTEIN; UNCLASSIFIED DRUG;

EID: 8144226985     PISSN: 00192805     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1365-2567.2004.01988.x     Document Type: Review
Times cited : (178)

References (133)
  • 1
    • 0024408824 scopus 로고
    • Two types of mouse T helper cell. IV. Th2 clones secrete a factor that inhibits cytokine production by Th1 clones
    • Fiorentino DF, Bond MW, Mosmann TR. Two types of mouse T helper cell. IV. Th2 clones secrete a factor that inhibits cytokine production by Th1 clones. J Exp Med 1989; 170:2081-95.'
    • (1989) J Exp Med , vol.170 , pp. 2081-2095
    • Fiorentino, D.F.1    Bond, M.W.2    Mosmann, T.R.3
  • 3
    • 0038283161 scopus 로고    scopus 로고
    • Interleukin-10 therapy - Review of a new approach
    • Asadullah K, Sterry W, Volk HD. Interleukin-10 therapy - review of a new approach. Pharmacol Rev 2003; 55:241-69.
    • (2003) Pharmacol Rev , vol.55 , pp. 241-269
    • Asadullah, K.1    Sterry, W.2    Volk, H.D.3
  • 4
    • 0025224135 scopus 로고
    • Expression of interleukin-10 activity by Epstein-Barr virus protein BCRF1
    • Hsu DH, de Waal Malefyt R, Fiorentino DF et al. Expression of interleukin-10 activity by Epstein-Barr virus protein BCRF1. Science 1990; 250:830-2.
    • (1990) Science , vol.250 , pp. 830-832
    • Hsu, D.H.1    De Waal Malefyt, R.2    Fiorentino, D.F.3
  • 6
    • 0027317738 scopus 로고
    • Interleukin-10 production by human carcinoma cell lines and its relationship to interleukin-6 expression
    • Gastl GA, Abrams JS, Nanus DM et al. Interleukin-10 production by human carcinoma cell lines and its relationship to interleukin-6 expression. Int J Cancer 1993; 55:96-101.
    • (1993) Int J Cancer , vol.55 , pp. 96-101
    • Gastl, G.A.1    Abrams, J.S.2    Nanus, D.M.3
  • 7
    • 0029121415 scopus 로고
    • IL-10 production in cutaneous basal and squamous cell carcinomas. A mechanism for evading the local T cell immune response
    • Kim J, Modlin RL, Moy RL, Dubinett SM, McHugh T, Nickoloff BJ, Uyemura K. IL-10 production in cutaneous basal and squamous cell carcinomas. A mechanism for evading the local T cell immune response. J Immunol 1995; 155:2240-7.
    • (1995) J Immunol , vol.155 , pp. 2240-2247
    • Kim, J.1    Modlin, R.L.2    Moy, R.L.3    Dubinett, S.M.4    McHugh, T.5    Nickoloff, B.J.6    Uyemura, K.7
  • 8
    • 0034763562 scopus 로고    scopus 로고
    • Cytokines and immune response in the tumor microenvironment
    • Mocellin S, Wang E, Marincola FM. Cytokines and immune response in the tumor microenvironment. J Immunother 2001; 24:392-407.
    • (2001) J Immunother , vol.24 , pp. 392-407
    • Mocellin, S.1    Wang, E.2    Marincola, F.M.3
  • 9
    • 17744373448 scopus 로고    scopus 로고
    • Interleukin 20: Discovery, receptor identification, and role in epidermal function
    • Blumberg H, Conklin D, Xu WF et al. Interleukin 20: discovery, receptor identification, and role in epidermal function. Cell 2001; 104:9-19.
    • (2001) Cell , vol.104 , pp. 9-19
    • Blumberg, H.1    Conklin, D.2    Xu, W.F.3
  • 10
    • 0034303102 scopus 로고    scopus 로고
    • Cloning, expression and initial characterization of interleukin-19 (IL-19), a novel homologue of human interleukin-10 (IL-10)
    • Gallagher G, Dickensheets H, Eskdale J et al. Cloning, expression and initial characterization of interleukin-19 (IL-19), a novel homologue of human interleukin-10 (IL-10). Genes Immun 2000; 1:442-50.
    • (2000) Genes Immun , vol.1 , pp. 442-450
    • Gallagher, G.1    Dickensheets, H.2    Eskdale, J.3
  • 11
    • 0035877222 scopus 로고    scopus 로고
    • Cloning and characterization of IL-22 binding protein, a natural antagonist of IL-10-related T cell-derived inducible factor/IL-22
    • Dumoutier L, Lejeune D, Colau D, Renauld JC. Cloning and characterization of IL-22 binding protein, a natural antagonist of IL-10-related T cell-derived inducible factor/ IL-22. J Immunol 2001; 166:7090-5.
    • (2001) J Immunol , vol.166 , pp. 7090-7095
    • Dumoutier, L.1    Lejeune, D.2    Colau, D.3    Renauld, J.C.4
  • 12
    • 0029558740 scopus 로고
    • Subtraction hybridization identifies a novel melanoma differentiation associated gene, mda-7, modulated during human melanoma differentiation, growth and progression
    • Jiang H, Lin JJ, Su ZZ, Goldstein NI, Fisher PB. Subtraction hybridization identifies a novel melanoma differentiation associated gene, mda-7, modulated during human melanoma differentiation, growth and progression. Oncogene 1995; 11:2477-86.
    • (1995) Oncogene , vol.11 , pp. 2477-2486
    • Jiang, H.1    Lin, J.J.2    Su, Z.Z.3    Goldstein, N.I.4    Fisher, P.B.5
  • 13
    • 0342803595 scopus 로고    scopus 로고
    • Induction of a novel cellular homolog of interleukin-10, AK155, by transformation of T lymphocytes with herpesvirus saimiri
    • Knappe A, Hor S, Wittmann S, Fickenscher H. Induction of a novel cellular homolog of interleukin-10, AK155, by transformation of T lymphocytes with herpesvirus saimiri. J Virol 2000; 74:3881-7.
    • (2000) J Virol , vol.74 , pp. 3881-3887
    • Knappe, A.1    Hor, S.2    Wittmann, S.3    Fickenscher, H.4
  • 14
    • 0027959650 scopus 로고
    • Two inhibitors of pro-inflammatory cytokine release, interleukin-10 and interleukin-4, have contrasting effects on release of soluble p75 tumor necrosis factor receptor by cultured monocytes
    • Joyce DA, Gibbons DP, Green P, Steer JH, Feldmann M, Brennan FM. Two inhibitors of pro-inflammatory cytokine release, interleukin-10 and interleukin-4, have contrasting effects on release of soluble p75 tumor necrosis factor receptor by cultured monocytes. Eur J Immunol 1994; 24:2699-705.
    • (1994) Eur J Immunol , vol.24 , pp. 2699-2705
    • Joyce, D.A.1    Gibbons, D.P.2    Green, P.3    Steer, J.H.4    Feldmann, M.5    Brennan, F.M.6
  • 15
    • 0028261520 scopus 로고
    • The effects of interleukin-10 on interleukin-1 receptor antagonist and interleukin-1 beta production in human monocytes and neutrophils
    • Jenkins JK, Malyak M, Arend WP. The effects of interleukin-10 on interleukin-1 receptor antagonist and interleukin-1 beta production in human monocytes and neutrophils. Lymphokine Cytokine Res 1994; 13:47-54.
    • (1994) Lymphokine Cytokine Res , vol.13 , pp. 47-54
    • Jenkins, J.K.1    Malyak, M.2    Arend, W.P.3
  • 16
    • 0028855894 scopus 로고
    • IL-10 inhibits metalloproteinase and stimulates TIMP-1 production in human mononuclear phagocytes
    • Lacraz S, Nicod LP, Chicheportiche R, Welgus HG, Dayer JM. IL-10 inhibits metalloproteinase and stimulates TIMP-1 production in human mononuclear phagocytes. J Clin Invest 1995; 96:2304-10.
    • (1995) J Clin Invest , vol.96 , pp. 2304-2310
    • Lacraz, S.1    Nicod, L.P.2    Chicheportiche, R.3    Welgus, H.G.4    Dayer, J.M.5
  • 17
    • 0028937751 scopus 로고
    • B7-1 expression of Langerhans cells is up-regulated by proinflammatory cytokines, and is down-regulated by interferon-gamma or by interleukin-10
    • Chang CH, Furue M, Tamaki K. B7-1 expression of Langerhans cells is up-regulated by proinflammatory cytokines, and is down-regulated by interferon-gamma or by interleukin-10. Eur J Immunol 1995; 25:394-8.
    • (1995) Eur J Immunol , vol.25 , pp. 394-398
    • Chang, C.H.1    Furue, M.2    Tamaki, K.3
  • 18
    • 0027239842 scopus 로고
    • IL-10 inhibits macrophage costimulatory activity by selectively inhibiting the up-regulation of B7 expression
    • Ding L, Linsley PS, Huang LY, Germain RN, Shevach EM. IL-10 inhibits macrophage costimulatory activity by selectively inhibiting the up-regulation of B7 expression. J Immunol 1993; 151:1224-34.
    • (1993) J Immunol , vol.151 , pp. 1224-1234
    • Ding, L.1    Linsley, P.S.2    Huang, L.Y.3    Germain, R.N.4    Shevach, E.M.5
  • 19
    • 0027232788 scopus 로고
    • + T cell clones and resting T cells. Specific inhibition of IL-2 production and proliferation
    • + T cell clones and resting T cells. Specific inhibition of IL-2 production and proliferation. J Immunol 1993; 150:4754-65.
    • (1993) J Immunol , vol.150 , pp. 4754-4765
    • De Waal Malefyt, R.1    Yssel, H.2    De Vries, J.E.3
  • 20
    • 0027281346 scopus 로고
    • Human interleukin-10 can directly inhibit T-cell growth
    • Taga K, Mostowski H, Tosato G. Human interleukin-10 can directly inhibit T-cell growth. Blood 1993; 81:2964-71.
    • (1993) Blood , vol.81 , pp. 2964-2971
    • Taga, K.1    Mostowski, H.2    Tosato, G.3
  • 21
    • 0028181890 scopus 로고
    • B7/CD28-dependent IL-5 production by human resting T cells is inhibited by IL-10
    • Schandene L, Alonso-Vega C, Willems F et al. B7/CD28-dependent IL-5 production by human resting T cells is inhibited by IL-10. J Immunol 1994; 152:4368-74.
    • (1994) J Immunol , vol.152 , pp. 4368-4374
    • Schandene, L.1    Alonso-Vega, C.2    Willems, F.3
  • 23
    • 0038273853 scopus 로고    scopus 로고
    • Blockade of B7-H1 improves myeloid dendritic cell-mediated antitumor immunity
    • Curiel TJ, Wei S, Dong H et al. Blockade of B7-H1 improves myeloid dendritic cell-mediated antitumor immunity. Nat Med 2003; 9:562-7.
    • (2003) Nat Med , vol.9 , pp. 562-567
    • Curiel, T.J.1    Wei, S.2    Dong, H.3
  • 24
    • 0037987977 scopus 로고    scopus 로고
    • Characterization of dendritic cells that induce tolerance and T regulatory 1 cell differentiation in vivo
    • Wakkach A, Fournier N, Brun V, Breittmayer JP, Cottrez F, Groux H. Characterization of dendritic cells that induce tolerance and T regulatory 1 cell differentiation in vivo. Immunity 2003; 18:605-17.
    • (2003) Immunity , vol.18 , pp. 605-617
    • Wakkach, A.1    Fournier, N.2    Brun, V.3    Breittmayer, J.P.4    Cottrez, F.5    Groux, H.6
  • 25
    • 0034890907 scopus 로고    scopus 로고
    • Pulmonary dendritic cells producing IL-10 mediate tolerance induced by respiratory exposure to antigen
    • Akbari O, DeKruyff RH, Umetsu DT. Pulmonary dendritic cells producing IL-10 mediate tolerance induced by respiratory exposure to antigen. Nat Immunol 2001; 2:725-31.
    • (2001) Nat Immunol , vol.2 , pp. 725-731
    • Akbari, O.1    DeKruyff, R.H.2    Umetsu, D.T.3
  • 26
    • 0027301117 scopus 로고
    • Human B cell precursors proliferate and express CD23 after CD40 ligation
    • Saeland S, Ouvert V, Moreau I, Banchereau J. Human B cell precursors proliferate and express CD23 after CD40 ligation. J Exp Med 1993; 178:113-20.
    • (1993) J Exp Med , vol.178 , pp. 113-120
    • Saeland, S.1    Ouvert, V.2    Moreau, I.3    Banchereau, J.4
  • 27
    • 0026584291 scopus 로고
    • Interleukin 10 is a potent growth and differentiation factor for activated human B lymphocytes
    • Roussel F, Garcia E, Defrance T et al. Interleukin 10 is a potent growth and differentiation factor for activated human B lymphocytes. Proc Natl Acad Sci USA 1992; 89:1890-3.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 1890-1893
    • Roussel, F.1    Garcia, E.2    Defrance, T.3
  • 29
    • 0028962115 scopus 로고
    • Role of interleukin 10 in the B lymphocyte hyperactivity and autoantibody production of human systemic lupus erythematosus
    • Llorente L, Zou W, Levy Y et al. Role of interleukin 10 in the B lymphocyte hyperactivity and autoantibody production of human systemic lupus erythematosus. J Exp Med 1995; 181:839-44.
    • (1995) J Exp Med , vol.181 , pp. 839-844
    • Llorente, L.1    Zou, W.2    Levy, Y.3
  • 30
    • 0033883903 scopus 로고    scopus 로고
    • Clinical and biologic effects of anti-interleukin-10 monoclonal antibody administration in systemic lupus erythematosus
    • Llorente L, Richaud-Patin Y, Garcia-Padilla C et al. Clinical and biologic effects of anti-interleukin-10 monoclonal antibody administration in systemic lupus erythematosus. Arthritis Rheum 2000; 43:1790-1800.
    • (2000) Arthritis Rheum , vol.43 , pp. 1790-1800
    • Llorente, L.1    Richaud-Patin, Y.2    Garcia-Padilla, C.3
  • 31
    • 0027478367 scopus 로고
    • Interleukin 10 reduces the release of tumor necrosis factor and prevents lethality in experimental endotoxemia
    • Gerard C, Bruyns C, Marchant A et al. Interleukin 10 reduces the release of tumor necrosis factor and prevents lethality in experimental endotoxemia. J Exp Med 1993; 177:547-50.
    • (1993) J Exp Med , vol.177 , pp. 547-550
    • Gerard, C.1    Bruyns, C.2    Marchant, A.3
  • 33
    • 0037369649 scopus 로고    scopus 로고
    • Local delivery of adenoviral vectors encoding murine interleukin 10 induces colonic interleukin 10 production and is therapeutic for murine colitis
    • Lindsay JO, Ciesielski CJ, Scheinin T, Brennan FM, Hodgson HJ. Local delivery of adenoviral vectors encoding murine interleukin 10 induces colonic interleukin 10 production and is therapeutic for murine colitis. Gut 2003; 52:363-9.
    • (2003) Gut , vol.52 , pp. 363-369
    • Lindsay, J.O.1    Ciesielski, C.J.2    Scheinin, T.3    Brennan, F.M.4    Hodgson, H.J.5
  • 35
    • 0030267816 scopus 로고    scopus 로고
    • Exposure to T helper 2 cytokines in vivo before encounter with antigen selects for T helper subsets via alterations in antigen-presenting cell function
    • Cua DJ, Coffman RL, Stohlman SA. Exposure to T helper 2 cytokines in vivo before encounter with antigen selects for T helper subsets via alterations in antigen-presenting cell function. J Immunol 1996; 157:2830-6.
    • (1996) J Immunol , vol.157 , pp. 2830-2836
    • Cua, D.J.1    Coffman, R.L.2    Stohlman, S.A.3
  • 36
    • 0033559981 scopus 로고    scopus 로고
    • Transgenic interleukin 10 prevents induction of experimental autoimmune encephalomyelitis
    • Cua DJ, Groux H, Hinton DR, Stohlman SA, Coffman RL. Transgenic interleukin 10 prevents induction of experimental autoimmune encephalomyelitis. J Exp Med 1999; 189:1005-10.
    • (1999) J Exp Med , vol.189 , pp. 1005-1010
    • Cua, D.J.1    Groux, H.2    Hinton, D.R.3    Stohlman, S.A.4    Coffman, R.L.5
  • 38
    • 0034463305 scopus 로고    scopus 로고
    • Recombinant human interleukin 10 in the treatment of patients with mild to moderately active Crohn's disease
    • The Interleukin 10 Inflammatory Bowel Disease Cooperative Study Group
    • Fedorak RN, Gangl A, Elson CO et al. Recombinant human interleukin 10 in the treatment of patients with mild to moderately active Crohn's disease. The Interleukin 10 Inflammatory Bowel Disease Cooperative Study Group. Gastroenterology 2000; 119:1473-82.
    • (2000) Gastroenterology , vol.119 , pp. 1473-1482
    • Fedorak, R.N.1    Gangl, A.2    Elson, C.O.3
  • 39
    • 0031697062 scopus 로고    scopus 로고
    • IL-10 as a therapeutic strategy in the treatment of rheumatoid arthritis
    • Keystone E, Wherry J, Grint P. IL-10 as a therapeutic strategy in the treatment of rheumatoid arthritis. Rheum Dis Clin North Am 1998; 24:629-39.
    • (1998) Rheum Dis Clin North Am , vol.24 , pp. 629-639
    • Keystone, E.1    Wherry, J.2    Grint, P.3
  • 40
    • 0028350053 scopus 로고
    • Expression cloning and characterization of a human IL-10 receptor
    • Liu Y, Wei SH, Ho AS, de Waal Malefyt R, Moore KW. Expression cloning and characterization of a human IL-10 receptor. J Immunol 1994; 152:1821-9.
    • (1994) J Immunol , vol.152 , pp. 1821-1829
    • Liu, Y.1    Wei, S.H.2    Ho, A.S.3    De Waal Malefyt, R.4    Moore, K.W.5
  • 41
    • 0030799157 scopus 로고    scopus 로고
    • Identification and functional characterization of a second chain of the interleukin-10 receptor complex
    • Kotenko S, Krause CD, Izotova LS, Pollack BP, Wu W, Pestka S. Identification and functional characterization of a second chain of the interleukin-10 receptor complex. EMBO J 1997; 16:5894-903.
    • (1997) EMBO J , vol.16 , pp. 5894-5903
    • Kotenko, S.1    Krause, C.D.2    Izotova, L.S.3    Pollack, B.P.4    Wu, W.5    Pestka, S.6
  • 42
    • 0032536530 scopus 로고    scopus 로고
    • The orphan receptor CRF2-4 is an essential subunit of the interleukin 10 receptor
    • Spencer SD, Di Marco F, Hooley J et al. The orphan receptor CRF2-4 is an essential subunit of the interleukin 10 receptor. J Exp Med 1998; 187:571-8.
    • (1998) J Exp Med , vol.187 , pp. 571-578
    • Spencer, S.D.1    Di Marco, F.2    Hooley, J.3
  • 43
    • 0037452789 scopus 로고    scopus 로고
    • STAT3 deletion during hematopoiesis causes Crohn's disease-like pathogenesis and lethality: A critical role of STAT3 in innate immunity
    • Weite T, Zhang SS, Wang T et al. STAT3 deletion during hematopoiesis causes Crohn's disease-like pathogenesis and lethality: a critical role of STAT3 in innate immunity. Proc Natl Acad Sci USA 2003; 100:1879-84.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 1879-1884
    • Weite, T.1    Zhang, S.S.2    Wang, T.3
  • 44
    • 0033696404 scopus 로고    scopus 로고
    • Partial impairment of cytokine responses in Tyk2-deficient mice
    • Karaghiosoff M, Neubauer H, Lassnig C et al. Partial impairment of cytokine responses in Tyk2-deficient mice. Immunity 2000; 13:549-60.
    • (2000) Immunity , vol.13 , pp. 549-560
    • Karaghiosoff, M.1    Neubauer, H.2    Lassnig, C.3
  • 46
    • 0032481383 scopus 로고    scopus 로고
    • IL-10 inhibits macrophage activation and proliferation by distinct signaling mechanisms, evidence for Stat3-dependent and -independent pathways
    • O'Farrell AM, Liu Y, Moore KW, Mui AL. IL-10 inhibits macrophage activation and proliferation by distinct signaling mechanisms, evidence for Stat3-dependent and -independent pathways. EMBO J 1998; 17:1006-18.
    • (1998) EMBO J , vol.17 , pp. 1006-1018
    • O'Farrell, A.M.1    Liu, Y.2    Moore, K.W.3    Mui, A.L.4
  • 47
    • 0033523019 scopus 로고    scopus 로고
    • Interleukin-10 receptor signaling through the JAK-STAT pathway. Requirement for two distinct receptor-derived signals for anti-inflammatory action
    • Riley JK, Takeda K, Akira S, Schreiber RD. Interleukin-10 receptor signaling through the JAK-STAT pathway. Requirement for two distinct receptor-derived signals for anti-inflammatory action. J Biol Chem 1999; 274:16513-21.
    • (1999) J Biol Chem , vol.274 , pp. 16513-16521
    • Riley, J.K.1    Takeda, K.2    Akira, S.3    Schreiber, R.D.4
  • 48
    • 17544375691 scopus 로고    scopus 로고
    • Receptors for interleukin (IL)-10 and IL-6-type cytokines use similar signaling mechanisms for inducing transcription through IL-6 response elements
    • Lai CF, Ripperger J, Morella KK et al. Receptors for interleukin (IL)-10 and IL-6-type cytokines use similar signaling mechanisms for inducing transcription through IL-6 response elements. J Biol Chem 1996; 271:13968-75.
    • (1996) J Biol Chem , vol.271 , pp. 13968-13975
    • Lai, C.F.1    Ripperger, J.2    Morella, K.K.3
  • 49
    • 0035951795 scopus 로고    scopus 로고
    • Identification of the functional interleukin-22 (IL-22) receptor complex. The IL-10R2 chain (IL-10Rbeta) is a common chain of both the IL-10 and IL-22 (IL-10-related T cell-derived inducible factor, IL-TIF) receptor complexes
    • Kotenko SV, Izotova LS, Mirochnitchenko OV, Esterova E, Dickensheets H, Donnelly RP, Pestka S. Identification of the functional interleukin-22 (IL-22) receptor complex. The IL-10R2 chain (IL-10Rbeta) is a common chain of both the IL-10 and IL-22 (IL-10-related T cell-derived inducible factor, IL-TIF) receptor complexes. J Biol Chem 2001; 276:2725-32.
    • (2001) J Biol Chem , vol.276 , pp. 2725-2732
    • Kotenko, S.V.1    Izotova, L.S.2    Mirochnitchenko, O.V.3    Esterova, E.4    Dickensheets, H.5    Donnelly, R.P.6    Pestka, S.7
  • 50
    • 0035992506 scopus 로고    scopus 로고
    • The family of IL-10-related cytokines and their receptors; related, but to what extent?
    • Kotenko SV. The family of IL-10-related cytokines and their receptors; related, but to what extent? Cytokine Growth Factor Rev 2002; 13:223-40.
    • (2002) Cytokine Growth Factor Rev , vol.13 , pp. 223-240
    • Kotenko, S.V.1
  • 51
    • 0034613201 scopus 로고    scopus 로고
    • Interleukin (IL) -22, a novel human cytokine that signals through the interferon receptor-related proteins CRF2-4 and IL-22R
    • Xie MH, Aggarwal S, Ho WH et al. Interleukin (IL) -22, a novel human cytokine that signals through the interferon receptor-related proteins CRF2-4 and IL-22R. J Biol Chem 2000; 275:31335-9.
    • (2000) J Biol Chem , vol.275 , pp. 31335-31339
    • Xie, M.H.1    Aggarwal, S.2    Ho, W.H.3
  • 52
    • 2342444617 scopus 로고    scopus 로고
    • Full house: 12 Receptors for 27 cytokines
    • Kotenko SV, Langer JA. Full house: 12 receptors for 27 cytokines. Int Immunopharmacol 2004; 4:593-608.
    • (2004) Int Immunopharmacol , vol.4 , pp. 593-608
    • Kotenko, S.V.1    Langer, J.A.2
  • 53
    • 3442888513 scopus 로고    scopus 로고
    • The expanded family of class II cytokines that share the IL-10 receptor-2 (IL-10R2) chain
    • Donnelly RP, Sheikh F, Kotenko SV, Dickensheets H. The expanded family of class II cytokines that share the IL-10 receptor-2 (IL-10R2) chain. J Leukoc Biol 2004; 76:314-21.
    • (2004) J Leukoc Biol , vol.76 , pp. 314-321
    • Donnelly, R.P.1    Sheikh, F.2    Kotenko, S.V.3    Dickensheets, H.4
  • 54
    • 10744224062 scopus 로고    scopus 로고
    • Cutting edge. IL-26 signals through a novel receptor complex composed of IL-20 receptor 1 and IL-10 receptor 2
    • Sheikh F, Baurin VV, Lewis-Antes A et al. Cutting edge. IL-26 signals through a novel receptor complex composed of IL-20 receptor 1 and IL-10 receptor 2. J Immunol 2004; 172:2006-10.
    • (2004) J Immunol , vol.172 , pp. 2006-2010
    • Sheikh, F.1    Baurin, V.V.2    Lewis-Antes, A.3
  • 55
    • 0037072796 scopus 로고    scopus 로고
    • Interleukin-22 (IL-22) activates the JAK/STAT, ERK, JNK, and p38 MAP kinase pathways in a rat hepatoma cell line. Pathways that are shared with and distinct from IL-10
    • Lejeune D, Dumoutier L, Constantinescu S, Kruijer W, Schuringa JJ, Renauld JC. Interleukin-22 (IL-22) activates the JAK/STAT, ERK, JNK, and p38 MAP kinase pathways in a rat hepatoma cell line. Pathways that are shared with and distinct from IL-10. J Biol Chem 2002; 277:33676-82.
    • (2002) J Biol Chem , vol.277 , pp. 33676-33682
    • Lejeune, D.1    Dumoutier, L.2    Constantinescu, S.3    Kruijer, W.4    Schuringa, J.J.5    Renauld, J.C.6
  • 56
    • 4043164894 scopus 로고    scopus 로고
    • The T-cell lymphokine interleukin-26 targets epithelial cells through the interleukin-20 receptor 1 and interleukin-10 receptor 2 chains
    • Hor S, Pirzer H, Dumoutier L et al. The T-cell lymphokine interleukin-26 targets epithelial cells through the interleukin-20 receptor 1 and interleukin-10 receptor 2 chains. J Biol Chem 2004; 279:33343-51.
    • (2004) J Biol Chem , vol.279 , pp. 33343-33351
    • Hor, S.1    Pirzer, H.2    Dumoutier, L.3
  • 57
    • 0034730141 scopus 로고    scopus 로고
    • Human interleukin-10-related T cell-derived inducible factor: Molecular cloning and functional characterization as an hepatocyte-stimulating factor
    • Dumoutier L, Van Roost E, Colau D, Renauld JC. Human interleukin-10- related T cell-derived inducible factor: molecular cloning and functional characterization as an hepatocyte-stimulating factor. Proc Natl Acad Sci USA 2000; 97:10144-9.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 10144-10149
    • Dumoutier, L.1    Van Roost, E.2    Colau, D.3    Renauld, J.C.4
  • 58
    • 2142653517 scopus 로고    scopus 로고
    • Expression patterns of IL-10 ligand and receptor gene families provide leads for biological characterization
    • Nagalakshmi ML, Murphy E, McClanahan T, de Waal Malefyt R. Expression patterns of IL-10 ligand and receptor gene families provide leads for biological characterization. Int Immunopharmacol 2004; 4:577-92.
    • (2004) Int Immunopharmacol , vol.4 , pp. 577-592
    • Nagalakshmi, M.L.1    Murphy, E.2    McClanahan, T.3    De Waal Malefyt, R.4
  • 60
    • 2342462460 scopus 로고    scopus 로고
    • Interleukin 22 (IL-22) plays a protective role in T cell-mediated murine hepatitis: IL-22 is a survival factor for hepatocytes via STAT3 activation
    • Radaeva S, Sun R, Pan HN, Hong F, Gao B. Interleukin 22 (IL-22) plays a protective role in T cell-mediated murine hepatitis: IL-22 is a survival factor for hepatocytes via STAT3 activation. Hepatology 2004; 39:1332-42.
    • (2004) Hepatology , vol.39 , pp. 1332-1342
    • Radaeva, S.1    Sun, R.2    Pan, H.N.3    Hong, F.4    Gao, B.5
  • 62
    • 0036681629 scopus 로고    scopus 로고
    • Two distinct domains within the N-terminal region of Janus kinase 1 interact with cytokine receptors
    • Usacheva A, Kotenko S, Witte MM, Colamonici OR. Two distinct domains within the N-terminal region of Janus kinase 1 interact with cytokine receptors. J Immunol 2002; 169:1302-8.
    • (2002) J Immunol , vol.169 , pp. 1302-1308
    • Usacheva, A.1    Kotenko, S.2    Witte, M.M.3    Colamonici, O.R.4
  • 64
    • 0029148046 scopus 로고
    • Functional regions of the mouse interleukin-10 receptor cytoplasmic domain
    • Ho AS, Wei SH, Mui AL, Miyajima A, Moore KW. Functional regions of the mouse interleukin-10 receptor cytoplasmic domain. Mol Cell Biol 1995; 15:5043-53.
    • (1995) Mol Cell Biol , vol.15 , pp. 5043-5053
    • Ho, A.S.1    Wei, S.H.2    Mui, A.L.3    Miyajima, A.4    Moore, K.W.5
  • 65
    • 0038528224 scopus 로고    scopus 로고
    • Novel variants of the IL-10 receptor 1 affect inhibition of monocyte TNF-alpha production
    • Gasche C, Grundtner P, Zwirn P et al. Novel variants of the IL-10 receptor 1 affect inhibition of monocyte TNF-alpha production. J Immunol 2003; 170:5578-82.
    • (2003) J Immunol , vol.170 , pp. 5578-5582
    • Gasche, C.1    Grundtner, P.2    Zwirn, P.3
  • 66
    • 0029118395 scopus 로고
    • IL-10 induces the tyrosine phosphorylation of Tyk2 and Jak1 and the differential assembly of STAT1 alpha and STAT3 complexes in human T cells and monocytes
    • Finbloom DS, Winestock KD. IL-10 induces the tyrosine phosphorylation of Tyk2 and Jak1 and the differential assembly of STAT1 alpha and STAT3 complexes in human T cells and monocytes. J Immunol 1995; 155:1079-90.
    • (1995) J Immunol , vol.155 , pp. 1079-1090
    • Finbloom, D.S.1    Winestock, K.D.2
  • 67
    • 0027446710 scopus 로고
    • Tyrosine phosphorylation of DNA binding proteins by multiple cytokines
    • Lamer A, David M, Feldman GM et al. Tyrosine phosphorylation of DNA binding proteins by multiple cytokines. Science 1993; 261:1730-3.
    • (1993) Science , vol.261 , pp. 1730-1733
    • Lamer, A.1    David, M.2    Feldman, G.M.3
  • 68
    • 0030573991 scopus 로고    scopus 로고
    • IL-10 induces DNA binding activity of three STAT proteins (Stat1, Stat3, and Stat5) and their distinct combinatorial assembly in the promoters of selected genes
    • Wehinger J, Gouilleux F, Groner B, Finke J, Mertelsmann R. Weber-Nordt RM. IL-10 induces DNA binding activity of three STAT proteins (Stat1, Stat3, and Stat5) and their distinct combinatorial assembly in the promoters of selected genes. FEBS Lett 1996; 394:365-70.
    • (1996) FEBS Lett , vol.394 , pp. 365-370
    • Wehinger, J.1    Gouilleux, F.2    Groner, B.3    Finke, J.4    Mertelsmann, R.5    Weber-Nordt, R.M.6
  • 70
    • 0030024563 scopus 로고    scopus 로고
    • Targeted disruption of the mouse Stat1 gene results in compromised innate immunity to viral disease
    • Durbin JE, Hackenmiller R, Simon MC, Levy DE. Targeted disruption of the mouse Stat1 gene results in compromised innate immunity to viral disease. Cell 1996; 84:443-50.
    • (1996) Cell , vol.84 , pp. 443-450
    • Durbin, J.E.1    Hackenmiller, R.2    Simon, M.C.3    Levy, D.E.4
  • 71
    • 0037443661 scopus 로고    scopus 로고
    • Activation of STAT3 by IL-6 and IL-10 in primary human macrophages is differentially modulated by suppressor of cytokine signaling 3
    • Niemand C, Nimmesgern A, Haan S, Fischer P, Schaper F, Rossaint R, Heinrich PC, Muller-Newen G. Activation of STAT3 by IL-6 and IL-10 in primary human macrophages is differentially modulated by suppressor of cytokine signaling 3. J Immunol 2003; 170:3263-72.
    • (2003) J Immunol , vol.170 , pp. 3263-3272
    • Niemand, C.1    Nimmesgern, A.2    Haan, S.3    Fischer, P.4    Schaper, F.5    Rossaint, R.6    Heinrich, P.C.7    Muller-Newen, G.8
  • 72
    • 0346103717 scopus 로고    scopus 로고
    • Signal transducer and activator of transcription 3 is the dominant mediator of the anti-inflammatory effects of IL-10 in human macrophages
    • Williams L, Bradley L, Smith A, Foxwell B. Signal transducer and activator of transcription 3 is the dominant mediator of the anti-inflammatory effects of IL-10 in human macrophages. J Immunol 2004; 172:567-76.
    • (2004) J Immunol , vol.172 , pp. 567-576
    • Williams, L.1    Bradley, L.2    Smith, A.3    Foxwell, B.4
  • 74
    • 0037938816 scopus 로고    scopus 로고
    • SOCS3 negatively regulates IL-6 signaling in vivo
    • Croker BA, Krebs DL, Zhang JG et al. SOCS3 negatively regulates IL-6 signaling in vivo. Nat Immunol 2003; 4:540-5.
    • (2003) Nat Immunol , vol.4 , pp. 540-545
    • Croker, B.A.1    Krebs, D.L.2    Zhang, J.G.3
  • 75
    • 0037600741 scopus 로고    scopus 로고
    • IL-6 induces an anti-inflammatory response in the absence of SOCS3 in macrophages
    • Yasukawa H, Ohishi M, Mori H et al. IL-6 induces an anti-inflammatory response in the absence of SOCS3 in macrophages. Nat Immunol 2003; 4:551-6.
    • (2003) Nat Immunol , vol.4 , pp. 551-556
    • Yasukawa, H.1    Ohishi, M.2    Mori, H.3
  • 76
    • 0035898647 scopus 로고    scopus 로고
    • Interleukin-10 targets p38 MAPK to modulate ARE-dependent TNF mRNA translation and limit intestinal pathology
    • Kontoyiannis D, Kotlyarov A, Carballo E et al. Interleukin-10 targets p38 MAPK to modulate ARE-dependent TNF mRNA translation and limit intestinal pathology. EMBO J 2001; 20:3760-70.
    • (2001) EMBO J , vol.20 , pp. 3760-3770
    • Kontoyiannis, D.1    Kotlyarov, A.2    Carballo, E.3
  • 78
    • 0026094306 scopus 로고
    • Interleukin 10 (IL-10) inhibits cytokine synthesis by human monocytes. An autoregulatory role of IL-10 produced by monocytes
    • de Waal Malefyt R, Abrams J, Bennett B, Figdor CG, de Vries JE. Interleukin 10 (IL-10) inhibits cytokine synthesis by human monocytes. an autoregulatory role of IL-10 produced by monocytes. J Exp Med 1991; 174:1209-20.
    • (1991) J Exp Med , vol.174 , pp. 1209-1220
    • De Waal Malefyt, R.1    Abrams, J.2    Bennett, B.3    Figdor, C.G.4    De Vries, J.E.5
  • 79
    • 0037093989 scopus 로고    scopus 로고
    • Evidence for a dual mechanism for IL-10 suppression of TNF-alpha production that does not involve inhibition of p38 mitogen-activated protein kinase or NF-kappa B in primary human macrophages
    • Denys A, Udalova IA, Smith C, Williams LM, Campbell J, Andrews C, Kwaitkowski D, Foxwell BM. Evidence for a dual mechanism for IL-10 suppression of TNF-alpha production that does not involve inhibition of p38 mitogen-activated protein kinase or NF-kappa B in primary human macrophages. J Immunol 2002; 168:4837-45.
    • (2002) J Immunol , vol.168 , pp. 4837-4845
    • Denys, A.1    Udalova, I.A.2    Smith, C.3    Williams, L.M.4    Campbell, J.5    Andrews, C.6    Kwaitkowski, D.7    Foxwell, B.M.8
  • 80
    • 0031569474 scopus 로고    scopus 로고
    • Attenuation of proinflammatory response by recombinant human IL-10 in human endotoxemia: Effect of timing of recombinant human IL-10 administration
    • Pajkrt D, Camoglio L, Tiel-van Buul MC et al. Attenuation of proinflammatory response by recombinant human IL-10 in human endotoxemia: effect of timing of recombinant human IL-10 administration. J Immunol 1997; 158:3971-7.
    • (1997) J Immunol , vol.158 , pp. 3971-3977
    • Pajkrt, D.1    Camoglio, L.2    Tiel-Van Buul, M.C.3
  • 81
  • 82
    • 0029874138 scopus 로고    scopus 로고
    • The NF-kappa B and I kappa B proteins: New discoveries and insights
    • Baldwin AS Jr. The NF-kappa B and I kappa B proteins: new discoveries and insights. Annu Rev Immunol 1996; 14:649-83.
    • (1996) Annu Rev Immunol , vol.14 , pp. 649-683
    • Baldwin Jr., A.S.1
  • 83
    • 0028972845 scopus 로고
    • Mechanistic aspects of NF-kappa B regulation: The emerging role of phosphorylation and proteolysis
    • Finco TS, Baldwin AS. Mechanistic aspects of NF-kappa B regulation: the emerging role of phosphorylation and proteolysis. Immunity 1995; 3:263-72.
    • (1995) Immunity , vol.3 , pp. 263-272
    • Finco, T.S.1    Baldwin, A.S.2
  • 84
    • 0036781052 scopus 로고    scopus 로고
    • NF-kappaB regulation in the immune system
    • Li Q, Verma IM. NF-kappaB regulation in the immune system. Nat Rev Immunol 2002; 2:725-34.
    • (2002) Nat Rev Immunol , vol.2 , pp. 725-734
    • Li, Q.1    Verma, I.M.2
  • 85
    • 0025186678 scopus 로고
    • Kappa B-type enhancers are involved in lipopolysaccharide-mediated transcriptional activation of the tumor necrosis factor alpha gene in primary macrophages
    • Shakhov AN, Collart MA, Vassalli P, Nedospasov SA, Jongeneel CV. Kappa B-type enhancers are involved in lipopolysaccharide-mediated transcriptional activation of the tumor necrosis factor alpha gene in primary macrophages. J Exp Med 1990; 171:35-47.
    • (1990) J Exp Med , vol.171 , pp. 35-47
    • Shakhov, A.N.1    Collart, M.A.2    Vassalli, P.3    Nedospasov, S.A.4    Jongeneel, C.V.5
  • 86
    • 0032516519 scopus 로고    scopus 로고
    • Complex NF-kappaB interactions at the distal tumor necrosis factor promoter region in human monocytes
    • Udalova IA, Knight JC, Vidal V, Nedospasov SA, Kwiatkowski D. Complex NF-kappaB interactions at the distal tumor necrosis factor promoter region in human monocytes. J Biol Chem 1998; 273:21178-86.
    • (1998) J Biol Chem , vol.273 , pp. 21178-21186
    • Udalova, I.A.1    Knight, J.C.2    Vidal, V.3    Nedospasov, S.A.4    Kwiatkowski, D.5
  • 87
  • 88
    • 0034746919 scopus 로고    scopus 로고
    • NF-kappaB; a key role in inflammatory diseases
    • Tak PP, Firestein GS. NF-kappaB; a key role in inflammatory diseases. J Clin Invest 2001; 107:7-11.
    • (2001) J Clin Invest , vol.107 , pp. 7-11
    • Tak, P.P.1    Firestein, G.S.2
  • 89
    • 0033104615 scopus 로고    scopus 로고
    • Selective regulation of cytokine induction by adenoviral gene transfer of IkappaBalpha into human macrophages: Lipopolysaccharide-induced, but not zymosan-induced, proinflammatory cytokines are inhibited, but IL-10 is nuclear factor-kappaB independent
    • Bondeson J, Browne KA, Brennan FM, Foxwell BM, Feldmann M. Selective regulation of cytokine induction by adenoviral gene transfer of IkappaBalpha into human macrophages: lipopolysaccharide-induced, but not zymosan-induced, proinflammatory cytokines are inhibited, but IL-10 is nuclear factor-kappaB independent. J Immunol 1999; 162:2939-45.
    • (1999) J Immunol , vol.162 , pp. 2939-2945
    • Bondeson, J.1    Browne, K.A.2    Brennan, F.M.3    Foxwell, B.M.4    Feldmann, M.5
  • 90
    • 0028948176 scopus 로고
    • Interleukin (IL)-10 inhibits nuclear factor kappa B (NF kappa B) activation in human monocytes. IL-10 and IL-4 suppress cytokine synthesis by different mechanisms
    • Wang P, Wu P, Siegel MI, Egan RW, Billah MM. Interleukin (IL)-10 inhibits nuclear factor kappa B (NF kappa B) activation in human monocytes. IL-10 and IL-4 suppress cytokine synthesis by different mechanisms. J Biol Chem 1995; 270:9558-63.
    • (1995) J Biol Chem , vol.270 , pp. 9558-9563
    • Wang, P.1    Wu, P.2    Siegel, M.I.3    Egan, R.W.4    Billah, M.M.5
  • 92
    • 0033527549 scopus 로고    scopus 로고
    • Interleukin-10 signaling blocks inhibitor of kappaB kinase activity and nuclear factor kappaB DNA binding
    • Schottelius AJ, Mayo MW, Sartor RB, Baldwin AS Jr. Interleukin-10 signaling blocks inhibitor of kappaB kinase activity and nuclear factor kappaB DNA binding. J Biol Chem 1999; 274:31868-74.
    • (1999) J Biol Chem , vol.274 , pp. 31868-31874
    • Schottelius, A.J.1    Mayo, M.W.2    Sartor, R.B.3    Baldwin Jr., A.S.4
  • 93
    • 3843104695 scopus 로고    scopus 로고
    • Immunoregulation of dendritic cells by IL-10 is mediated through suppression of the PI3K/Akt pathway and I{kappa} B kinase activity
    • Bhattacharyya S, Sen P, Wallet M, Long B, Baldwin AS, Tisch R. Immunoregulation of dendritic cells by IL-10 is mediated through suppression of the PI3K/Akt pathway and I{kappa} B kinase activity. Blood 2004; 10:1100-9.
    • (2004) Blood , vol.10 , pp. 1100-1109
    • Bhattacharyya, S.1    Sen, P.2    Wallet, M.3    Long, B.4    Baldwin, A.S.5    Tisch, R.6
  • 94
    • 1542314248 scopus 로고    scopus 로고
    • Interleukin-10 inhibits interleukin-12 p40 gene transcription by targeting a late event in the activation pathway
    • Zhou L, Nazarian AA, Smale ST. Interleukin-10 inhibits interleukin-12 p40 gene transcription by targeting a late event in the activation pathway. Mol Cell Biol 2004; 24:2385-96.
    • (2004) Mol Cell Biol , vol.24 , pp. 2385-2396
    • Zhou, L.1    Nazarian, A.A.2    Smale, S.T.3
  • 95
    • 0031944393 scopus 로고    scopus 로고
    • IL-10-mediated suppression of TNF-alpha production is independent of its ability to inhibit NF kappa B activity
    • Clarke CJ, Hales A, Hunt A, Foxwell BM. IL-10-mediated suppression of TNF-alpha production is independent of its ability to inhibit NF kappa B activity. Eur J Immunol 1998; 28:1719-26.
    • (1998) Eur J Immunol , vol.28 , pp. 1719-1726
    • Clarke, C.J.1    Hales, A.2    Hunt, A.3    Foxwell, B.M.4
  • 96
    • 0027144465 scopus 로고
    • Protein tyrosine kinase activation is required for lipopolysaccharide induction of cytokines in human blood monocytes
    • Geng Y, Zhang B, Lotz M. Protein tyrosine kinase activation is required for lipopolysaccharide induction of cytokines in human blood monocytes. J Immunol 1993; 151:6692-700.
    • (1993) J Immunol , vol.151 , pp. 6692-6700
    • Geng, Y.1    Zhang, B.2    Lotz, M.3
  • 97
    • 0028364801 scopus 로고
    • Lipopolysaccharide-induced cytokine production in human monocytes: Role of tyrosine phosphorylation in transmembrane signal transduction
    • Beaty CD, Franklin TL, Uehara Y, Wilson CB. Lipopolysaccharide-induced cytokine production in human monocytes: role of tyrosine phosphorylation in transmembrane signal transduction. Eur J Immunol 1994; 24:1278-84.
    • (1994) Eur J Immunol , vol.24 , pp. 1278-1284
    • Beaty, C.D.1    Franklin, T.L.2    Uehara, Y.3    Wilson, C.B.4
  • 98
    • 0031985903 scopus 로고    scopus 로고
    • Regulation of monocyte IL-10 synthesis by endogenous IL-1 and TNF-α: Role of the p38 and p42/44 mitogen-activated protein kinases
    • Foey AD, Parry SL, Williams LM, Feldmann M, Foxwell BMJ, Brennan FM. Regulation of monocyte IL-10 synthesis by endogenous IL-1 and TNF-α: Role of the p38 and p42/44 mitogen-activated protein kinases. J Immunol 1998; 160:920-8.
    • (1998) J Immunol , vol.160 , pp. 920-928
    • Foey, A.D.1    Parry, S.L.2    Williams, L.M.3    Feldmann, M.4    Foxwell, B.M.J.5    Brennan, F.M.6
  • 99
    • 0027934846 scopus 로고
    • Monocyte deactivation by interleukin 10 via inhibition of tyrosine kinase activity and the Ras signaling pathway
    • Geng Y, Gulbins E, Altman A. Lotz M. Monocyte deactivation by interleukin 10 via inhibition of tyrosine kinase activity and the Ras signaling pathway. Proc Natl Acad Sci USA 1994; 91:8602-6.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 8602-8606
    • Geng, Y.1    Gulbins, E.2    Altman, A.3    Lotz, M.4
  • 100
    • 0028605318 scopus 로고
    • A protein kinase involved in the regulation of inflammatory cytokine biosynthesis
    • Lee JC, Laydon JT, McDonnell PC et al. A protein kinase involved in the regulation of inflammatory cytokine biosynthesis. Nature 1994; 372:739-46.
    • (1994) Nature , vol.372 , pp. 739-746
    • Lee, J.C.1    Laydon, J.T.2    McDonnell, P.C.3
  • 101
    • 0038538477 scopus 로고    scopus 로고
    • Post-transcriptional regulation of gene expression by mitogen-activated protein kinase p38
    • Clark AR, Dean JL, Saklatvala J. Post-transcriptional regulation of gene expression by mitogen-activated protein kinase p38. FEBS Lett 2003; 546:37-44.
    • (2003) FEBS Lett , vol.546 , pp. 37-44
    • Clark, A.R.1    Dean, J.L.2    Saklatvala, J.3
  • 103
    • 0033103805 scopus 로고    scopus 로고
    • Impaired on/off regulation of TNF biosynthesis in mice lacking TNF AU-rich elements: Implications for joint and gut-associated immunopathologies
    • Kontoyiannis D, Pasparakis M, Pizarro TT, Cominelli F, Kollias G. Impaired on/off regulation of TNF biosynthesis in mice lacking TNF AU-rich elements: implications for joint and gut-associated immunopathologies. Immunity 1999; 10:387-88.
    • (1999) Immunity , vol.10 , pp. 387-388
    • Kontoyiannis, D.1    Pasparakis, M.2    Pizarro, T.T.3    Cominelli, F.4    Kollias, G.5
  • 104
    • 0032779561 scopus 로고    scopus 로고
    • The interleukin-10 signal transduction pathway and regulation of gene expression in mononuclear phagocytes
    • Donnelly RP, Dickensheets H, Finbloom DS. The interleukin-10 signal transduction pathway and regulation of gene expression in mononuclear phagocytes. J Interferon Cytokine Res 1999; 19:563-73.
    • (1999) J Interferon Cytokine Res , vol.19 , pp. 563-573
    • Donnelly, R.P.1    Dickensheets, H.2    Finbloom, D.S.3
  • 106
    • 0033104734 scopus 로고    scopus 로고
    • Cutting edge, clustered AU-rich elements are the target of IL-10-mediated mRNA destabilization in mouse macrophages
    • Kishore R, Tebo JM, Kolosov M, Hamilton TA. Cutting edge, clustered AU-rich elements are the target of IL-10-mediated mRNA destabilization in mouse macrophages. J Immunol 1999; 162:2457-61.
    • (1999) J Immunol , vol.162 , pp. 2457-2461
    • Kishore, R.1    Tebo, J.M.2    Kolosov, M.3    Hamilton, T.A.4
  • 107
    • 0032076183 scopus 로고    scopus 로고
    • Disruption of the Jak1 gene demonstrates obligatory and nonredundant roles of the Jaks in cytokine-induced biologic responses
    • Rodig SJ, Meraz MA, White JM et al. Disruption of the Jak1 gene demonstrates obligatory and nonredundant roles of the Jaks in cytokine-induced biologic responses. Cell 1998; 93:373-83.
    • (1998) Cell , vol.93 , pp. 373-383
    • Rodig, S.J.1    Meraz, M.A.2    White, J.M.3
  • 108
    • 0033034365 scopus 로고    scopus 로고
    • Enhanced Th1 activity and development of chronic enterocolitis in mice devoid of Stat3 in macrophages and neutrophils
    • Takeda K, Clausen BE, Kaisho T, Tsujimura T, Terada N, Forster I, Akira S. Enhanced Th1 activity and development of chronic enterocolitis in mice devoid of Stat3 in macrophages and neutrophils. Immunity 1999; 10:39-49.
    • (1999) Immunity , vol.10 , pp. 39-49
    • Takeda, K.1    Clausen, B.E.2    Kaisho, T.3    Tsujimura, T.4    Terada, N.5    Forster, I.6    Akira, S.7
  • 109
    • 4644261307 scopus 로고    scopus 로고
    • The STAT3 isoforms alpha and beta have unique and specific functions
    • Maritano D, Sugrue ML, Tininini S et al. The STAT3 isoforms alpha and beta have unique and specific functions. Nat Immunol 2004; 5:401-9.
    • (2004) Nat Immunol , vol.5 , pp. 401-409
    • Maritano, D.1    Sugrue, M.L.2    Tininini, S.3
  • 110
    • 0030037906 scopus 로고    scopus 로고
    • Interleukin-10 stimulation of phosphatidylinositol 3-kinase and p70, S6 kinase is required for the proliferative but not the antiinflammatory effects of the cytokine
    • Crawley JB, Williams LM, Mander T, Brennan FM, Foxwell BM. Interleukin-10 stimulation of phosphatidylinositol 3-kinase and p70, S6 kinase is required for the proliferative but not the antiinflammatory effects of the cytokine. J Biol Chem 1996; 271:16357-62.
    • (1996) J Biol Chem , vol.271 , pp. 16357-16362
    • Crawley, J.B.1    Williams, L.M.2    Mander, T.3    Brennan, F.M.4    Foxwell, B.M.5
  • 111
    • 0035887654 scopus 로고    scopus 로고
    • IL-10 inhibits apoptosis of promyeloid cells by activating insulin receptor substrate-2 and phosphatidylinositol 3′-kinase
    • Zhou JH, Broussard SR, Strle K, Freund GG, Johnson RW, Dantzer R, Kelley KW. IL-10 inhibits apoptosis of promyeloid cells by activating insulin receptor substrate-2 and phosphatidylinositol 3′-kinase. J Immunol 2001; 167:4436-42.
    • (2001) J Immunol , vol.167 , pp. 4436-4442
    • Zhou, J.H.1    Broussard, S.R.2    Strle, K.3    Freund, G.G.4    Johnson, R.W.5    Dantzer, R.6    Kelley, K.W.7
  • 112
    • 0033915344 scopus 로고    scopus 로고
    • Interleukin-10 and interleukin-13 inhibit proinflammatory cytokine-induced ceramide production through the activation of phosphatidylinositol 3-kinase
    • Pahan K, Khan M, Singh I. Interleukin-10 and interleukin-13 inhibit proinflammatory cytokine-induced ceramide production through the activation of phosphatidylinositol 3-kinase. J Neurochem 2000; 75:576-82.
    • (2000) J Neurochem , vol.75 , pp. 576-582
    • Pahan, K.1    Khan, M.2    Singh, I.3
  • 113
    • 0030070975 scopus 로고    scopus 로고
    • Bacterial lipopolysaccharide induces the association and coordinate activation of p53/561yn and phosphatidylinositol 3-kinase in human monocytes
    • Herrera-Velit P, Reiner NE. Bacterial lipopolysaccharide induces the association and coordinate activation of p53/561yn and phosphatidylinositol 3-kinase in human monocytes. J Immunol 1996; 156:1157-65.
    • (1996) J Immunol , vol.156 , pp. 1157-1165
    • Herrera-Velit, P.1    Reiner, N.E.2
  • 114
    • 0037199972 scopus 로고    scopus 로고
    • The Phosphatidylinositol 3-kinase-Akt pathway limits lipopolysaccheride activation of signalling pathways and expression of inflammatory mediators in human monocytic cells
    • Guha M, Mackman N. The Phosphatidylinositol 3-kinase-Akt pathway limits lipopolysaccheride activation of signalling pathways and expression of inflammatory mediators in human monocytic cells. J Biol Chem 2002; 277:32124-32.
    • (2002) J Biol Chem , vol.277 , pp. 32124-32132
    • Guha, M.1    Mackman, N.2
  • 115
    • 0346103719 scopus 로고    scopus 로고
    • Modulation of the phosphoinositide 3-kinase pathway alters innate resistance to polymicrobial sepsis
    • Williams DL, Li C, Ha T et al. Modulation of the phosphoinositide 3-kinase pathway alters innate resistance to polymicrobial sepsis. J Immunol 2004; 172:449-56.
    • (2004) J Immunol , vol.172 , pp. 449-456
    • Williams, D.L.1    Li, C.2    Ha, T.3
  • 116
    • 0032526338 scopus 로고    scopus 로고
    • Molecular mechanisms of the induction of IL-12 and its inhibition by IL-10
    • Aste-Amezaga M, Ma X, Sartori A, Trinchieri G. Molecular mechanisms of the induction of IL-12 and its inhibition by IL-10. J Immunol 1998; 160:5936-44.
    • (1998) J Immunol , vol.160 , pp. 5936-5944
    • Aste-Amezaga, M.1    Ma, X.2    Sartori, A.3    Trinchieri, G.4
  • 117
    • 0026457998 scopus 로고
    • Contrasting mechanisms for suppression of macrophage cytokine release by transforming growth factor-beta and interleukin 10
    • Bogdan C, Paik J, Vodovotz Y, Nathan C. Contrasting mechanisms for suppression of macrophage cytokine release by transforming growth factor-beta and interleukin 10. J Biol Chem 1992; 267:23301-8.
    • (1992) J Biol Chem , vol.267 , pp. 23301-23308
    • Bogdan, C.1    Paik, J.2    Vodovotz, Y.3    Nathan, C.4
  • 118
    • 0030587146 scopus 로고    scopus 로고
    • T helper 2 cytokines differently regulate monocyte chemoattractant protein-1 production by human peripheral blood monocytes and alveolar macrophages
    • Yano S, Yanagawa H, Nishioka Y, Mukaida N, Matsushima K. Sone S. T helper 2 cytokines differently regulate monocyte chemoattractant protein-1 production by human peripheral blood monocytes and alveolar macrophages. J Immunol 1996; 157:2660-5.
    • (1996) J Immunol , vol.157 , pp. 2660-2665
    • Yano, S.1    Yanagawa, H.2    Nishioka, Y.3    Mukaida, N.4    Matsushima, K.5    Sone, S.6
  • 119
    • 0032472865 scopus 로고    scopus 로고
    • Interleukin 10 increases CCR5 expression and HIV infection in human monocytes
    • Sozzani S, Ghezzi S, Iannolo G et al. Interleukin 10 increases CCR5 expression and HIV infection in human monocytes. J Exp Med 1998; 187:439-44.
    • (1998) J Exp Med , vol.187 , pp. 439-444
    • Sozzani, S.1    Ghezzi, S.2    Iannolo, G.3
  • 120
    • 0342905414 scopus 로고    scopus 로고
    • The scavenger receptor CD163: Regulation, promoter structure and genomic organization
    • Ritter M, Buechler C, Langmann T, Orso E, Klucken J, Schmitz G. The scavenger receptor CD163: regulation, promoter structure and genomic organization. Pathobiology 1999; 67:257-61.
    • (1999) Pathobiology , vol.67 , pp. 257-261
    • Ritter, M.1    Buechler, C.2    Langmann, T.3    Orso, E.4    Klucken, J.5    Schmitz, G.6
  • 121
    • 0030781492 scopus 로고    scopus 로고
    • Interleukin-10 upregulates tumor necrosis factor receptor type-II (p75) gene expression in endotoxin-stimulated human monocytes
    • Dickensheets HL, Freeman SL, Smith MF, Donnelly RP. Interleukin-10 upregulates tumor necrosis factor receptor type-II (p75) gene expression in endotoxin-stimulated human monocytes. Blood 1997; 90:4162-71.
    • (1997) Blood , vol.90 , pp. 4162-4171
    • Dickensheets, H.L.1    Freeman, S.L.2    Smith, M.F.3    Donnelly, R.P.4
  • 122
    • 0033104946 scopus 로고    scopus 로고
    • Interleukin-10 inhibits expression of both interferon alpha- and interferon gamma- induced genes by suppressing tyrosine phosphorylation of STAT1
    • Ito S, Ansari P, Sakatsume M, Dickensheets H, Vazquez N, Donnelly RP, Lamer AC, Finbloom DS. Interleukin-10 inhibits expression of both interferon alpha- and interferon gamma- induced genes by suppressing tyrosine phosphorylation of STAT1. Blood 1999; 93:1456-63.
    • (1999) Blood , vol.93 , pp. 1456-1463
    • Ito, S.1    Ansari, P.2    Sakatsume, M.3    Dickensheets, H.4    Vazquez, N.5    Donnelly, R.P.6    Lamer, A.C.7    Finbloom, D.S.8
  • 123
  • 124
    • 0036721716 scopus 로고    scopus 로고
    • Shaping gene expression in activated and resting primary macrophages by IL-10
    • Lang R, Patel D, Morris JJ, Rutschman RL, Murray PJ. Shaping gene expression in activated and resting primary macrophages by IL-10. J Immunol 2002; 169:2253-63.
    • (2002) J Immunol , vol.169 , pp. 2253-2263
    • Lang, R.1    Patel, D.2    Morris, J.J.3    Rutschman, R.L.4    Murray, P.J.5
  • 125
    • 1642402217 scopus 로고    scopus 로고
    • Expression profiling of IL-10-regulated genes in human monocytes and peripheral blood mononuclear cells from psoriatic patients during IL-10 therapy
    • Jung M, Sabat R, Kratzschmar J et al. Expression profiling of IL-10-regulated genes in human monocytes and peripheral blood mononuclear cells from psoriatic patients during IL-10 therapy. Eur J Immunol 2004; 34:481-493
    • (2004) Eur J Immunol , vol.34 , pp. 481-493
    • Jung, M.1    Sabat, R.2    Kratzschmar, J.3
  • 126
    • 0242433137 scopus 로고    scopus 로고
    • IL-10-inducible Bcl-3 negatively regulates LPS-induced TNF-alpha production in macrophages
    • Kuwata H, Watanabe Y, Miyoshi H, Yamamoto M, Kaisho T, Takeda K, Akira S. IL-10-inducible Bcl-3 negatively regulates LPS-induced TNF-alpha production in macrophages. Blood 2003; 102:4123-9.
    • (2003) Blood , vol.102 , pp. 4123-4129
    • Kuwata, H.1    Watanabe, Y.2    Miyoshi, H.3    Yamamoto, M.4    Kaisho, T.5    Takeda, K.6    Akira, S.7
  • 127
    • 2442694078 scopus 로고    scopus 로고
    • Distinct transcriptional programs activated by interleukin-10 with or without lipopolysaccharide in dendritic cells: Induction of the B cell-activating chemokine, CXC chemokine ligand 13
    • Perrier P, Martinez FO, Locati M et al. Distinct transcriptional programs activated by interleukin-10 with or without lipopolysaccharide in dendritic cells: induction of the B cell-activating chemokine, CXC chemokine ligand 13. J Immunol 2004; 172:7031-42.
    • (2004) J Immunol , vol.172 , pp. 7031-7042
    • Perrier, P.1    Martinez, F.O.2    Locati, M.3
  • 128
    • 0001487328 scopus 로고    scopus 로고
    • A novel family of Ig-like receptors for HLA class I molecules that modulate function of lymphoid and myeloid cells
    • Colonna M, Nakajima H, Navarro F, Lopez-Botet M. A novel family of Ig-like receptors for HLA class I molecules that modulate function of lymphoid and myeloid cells. J Leukoc Biol 1999; 66:375-81.
    • (1999) J Leukoc Biol , vol.66 , pp. 375-381
    • Colonna, M.1    Nakajima, H.2    Navarro, F.3    Lopez-Botet, M.4
  • 130
    • 0036122891 scopus 로고    scopus 로고
    • Tolerization of dendritic cells by T (S) cells: The crucial role of inhibitory receptors ILT3 and ILT4
    • Chang CC, Ciubotariu R, Manavalan JS et al. Tolerization of dendritic cells by T (S) cells: the crucial role of inhibitory receptors ILT3 and ILT4. Nat Immunol 2002; 3:237-43.
    • (2002) Nat Immunol , vol.3 , pp. 237-243
    • Chang, C.C.1    Ciubotariu, R.2    Manavalan, J.S.3
  • 131
    • 0036127426 scopus 로고    scopus 로고
    • Heme oxygenase-1 mediates the antiinflammatory effect of IL-10 in mice
    • Lee TS, Chau LY. Heme oxygenase-1 mediates the antiinflammatory effect of IL-10 in mice. Nat Med 2002; 8:240-6.
    • (2002) Nat Med , vol.8 , pp. 240-246
    • Lee, T.S.1    Chau, L.Y.2
  • 133
    • 4344584558 scopus 로고    scopus 로고
    • Heme oxygenase 1 expression induced by IL-10 requires STAT-3 and phosphoinositol-3 kinase and is inhibited by lipopolysaccharide
    • Ricchetti G, Williams LM, Foxwell BM. Heme oxygenase 1 expression induced by IL-10 requires STAT-3 and phosphoinositol-3 kinase and is inhibited by lipopolysaccharide. J Leukoc Biol 2004; 76:719-26.
    • (2004) J Leukoc Biol , vol.76 , pp. 719-726
    • Ricchetti, G.1    Williams, L.M.2    Foxwell, B.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.