메뉴 건너뛰기




Volumn 1, Issue 2, 1999, Pages 94-97

MAPKAP kinase 2 is essential for LPS-induced TNF-α biosynthesis

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; LIPOPOLYSACCHARIDE; MAP KINASE ACTIVATED KINASE 2; MAP-KINASE-ACTIVATED KINASE 2; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN SERINE THREONINE KINASE; TUMOR NECROSIS FACTOR ALPHA;

EID: 0033145354     PISSN: 14657392     EISSN: None     Source Type: Journal    
DOI: 10.1038/10061     Document Type: Article
Times cited : (708)

References (33)
  • 1
    • 0028022750 scopus 로고
    • A novel kinase cascade triggered by stress and heat shock that stimulates MAPKAP kinase-2 and phosphorylation of the small heat shock proteins
    • Rouse, J. et al. A novel kinase cascade triggered by stress and heat shock that stimulates MAPKAP kinase-2 and phosphorylation of the small heat shock proteins. Cell 78, 1027-1037 (1994).
    • (1994) Cell , vol.78 , pp. 1027-1037
    • Rouse, J.1
  • 2
    • 0028015872 scopus 로고
    • Interleukin-1 activates a novel protein kinase cascade that results in the phosphorylation of Hsp27
    • Freshney, N. W. et al. Interleukin-1 activates a novel protein kinase cascade that results in the phosphorylation of Hsp27. Cell 78, 1039-1049 (1994).
    • (1994) Cell , vol.78 , pp. 1039-1049
    • Freshney, N.W.1
  • 3
    • 0027936755 scopus 로고
    • A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells
    • Han, J., Lee, J. D., Bibbs, L. & Ulevitch, R. J. A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells. Science 265, 808-811 (1994).
    • (1994) Science , vol.265 , pp. 808-811
    • Han, J.1    Lee, J.D.2    Bibbs, L.3    Ulevitch, R.J.4
  • 4
    • 0030051528 scopus 로고    scopus 로고
    • MKK3- and MKK6-regulated gene expression is mediated by the p38 mitogen-activated protein kinase signal transduction pathway
    • Raingeaud, J., Whitmarsh, A. J., Barrett, T., Derijard, B. & Davis, R. J. MKK3- and MKK6-regulated gene expression is mediated by the p38 mitogen-activated protein kinase signal transduction pathway. Mol. Cell. Biol. 16, 1247-1255 (1996).
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 1247-1255
    • Raingeaud, J.1    Whitmarsh, A.J.2    Barrett, T.3    Derijard, B.4    Davis, R.J.5
  • 5
    • 0032540244 scopus 로고    scopus 로고
    • The phosphorylation of eukaryotic initiation factor eIF4E in response to phorbol esters, cell stresses, and cytokines is mediated by distinct MAP kinase pathways
    • Wang, X. et al. The phosphorylation of eukaryotic initiation factor eIF4E in response to phorbol esters, cell stresses, and cytokines is mediated by distinct MAP kinase pathways. J. Biol. Chem. 273, 9373-9377 (1998).
    • (1998) J. Biol. Chem. , vol.273 , pp. 9373-9377
    • Wang, X.1
  • 6
    • 0028880006 scopus 로고
    • Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis
    • Xia, Z., Dickens, M., Raingeaud, J., Davis, R. J. & Greenberg, M. E. Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis. Science 270, 1326-1331 (1995).
    • (1995) Science , vol.270 , pp. 1326-1331
    • Xia, Z.1    Dickens, M.2    Raingeaud, J.3    Davis, R.J.4    Greenberg, M.E.5
  • 7
    • 0032562716 scopus 로고    scopus 로고
    • Activation of the protein kinase p38 in the spindle assembly checkpoint and mitotic arrest
    • Takenaka, K., Moriguchi, T. & Nishida, E. Activation of the protein kinase p38 in the spindle assembly checkpoint and mitotic arrest. Science 280, 599-602 (1998).
    • (1998) Science , vol.280 , pp. 599-602
    • Takenaka, K.1    Moriguchi, T.2    Nishida, E.3
  • 8
    • 0028605318 scopus 로고
    • A protein kinase involved in the regulation of inflammatory cytokine biosynthesis
    • Lee, J.C. et al. A protein kinase involved in the regulation of inflammatory cytokine biosynthesis. Nature 372, 739-746 (1994).
    • (1994) Nature , vol.372 , pp. 739-746
    • Lee, J.C.1
  • 9
    • 0032520916 scopus 로고    scopus 로고
    • Inhibition of the p38 mitogen-activated protein kinase by SB203580 blocks PMA-induced Mr 92,000 type IV collagenase secretion and in vitro invasion
    • Simon, C., Goepfert, H. & Boyd, D. Inhibition of the p38 mitogen-activated protein kinase by SB203580 blocks PMA-induced Mr 92,000 type IV collagenase secretion and in vitro invasion. Cancer Res. 58, 1135-1139 (1998).
    • (1998) Cancer Res. , vol.58 , pp. 1135-1139
    • Simon, C.1    Goepfert, H.2    Boyd, D.3
  • 10
    • 0027761036 scopus 로고
    • Bicyclic imidazoles as a novel class of cytokine biosynthesis inhibitors
    • Lee, J.C. et al. Bicyclic imidazoles as a novel class of cytokine biosynthesis inhibitors. Ann. N.Y. Acad. Sci. 696, 149-170 (1993).
    • (1993) Ann. N.Y. Acad. Sci. , vol.696 , pp. 149-170
    • Lee, J.C.1
  • 11
    • 0032538817 scopus 로고    scopus 로고
    • The JNK pathway regulates the in vivo deletion of immature CD4(+)CD8(+) thymocytes
    • Rincon, M. et al. The JNK pathway regulates the in vivo deletion of immature CD4(+)CD8(+) thymocytes. J. Exp. Med. 188, 1817-3011.
    • J. Exp. Med. , vol.188 , pp. 1817-3011
    • Rincon, M.1
  • 12
    • 0026733636 scopus 로고
    • MAPKAP kinase-2; a novel protein kinase activated by mitogen-activated protein kinase
    • Stokoe, D. et al. MAPKAP kinase-2; a novel protein kinase activated by mitogen-activated protein kinase. EMBO J. 11, 3985-3994 (1992).
    • (1992) EMBO J. , vol.11 , pp. 3985-3994
    • Stokoe, D.1
  • 13
    • 9044220225 scopus 로고    scopus 로고
    • 3pK, a new mitogen-activated protein kinase-activated protein kinase located in the small cell lung cancer tumor suppressor gene
    • Sithanandam, G. et al. 3pK, a new mitogen-activated protein kinase-activated protein kinase located in the small cell lung cancer tumor suppressor gene. Mol. Cell. Biol. 16, 868-876 (1996).
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 868-876
    • Sithanandam, G.1
  • 14
    • 0030977270 scopus 로고    scopus 로고
    • MNK1, a new MAP kinase-activated protein kinase, isolated by a novel expression screening method for identifying protein kinase substrates
    • Fukunaga, R. & Hunter, T. MNK1, a new MAP kinase-activated protein kinase, isolated by a novel expression screening method for identifying protein kinase substrates. EMBO J. 16, 1921-1933 (1997).
    • (1997) EMBO J. , vol.16 , pp. 1921-1933
    • Fukunaga, R.1    Hunter, T.2
  • 15
    • 0030977269 scopus 로고    scopus 로고
    • Mitogen-activated protein kinases activate the serine/threonine kinases Mnk1 and Mnk2
    • Waskiewicz, A. J., Flynn, A., Proud, C. G. & Cooper, J. A. Mitogen-activated protein kinases activate the serine/threonine kinases Mnk1 and Mnk2. EMBO J. 16, 1909-1920 (1997).
    • (1997) EMBO J. , vol.16 , pp. 1909-1920
    • Waskiewicz, A.J.1    Flynn, A.2    Proud, C.G.3    Cooper, J.A.4
  • 16
    • 0032526694 scopus 로고    scopus 로고
    • PRAK, a novel protein kinase regulated by the p38 MAP kinase
    • New, L. et al. PRAK, a novel protein kinase regulated by the p38 MAP kinase. EMBO J. 17, 3372-3384 (1998).
    • (1998) EMBO J. , vol.17 , pp. 3372-3384
    • New, L.1
  • 17
    • 0032479983 scopus 로고    scopus 로고
    • Mitogen-and stress-activated protein kinase-1 (MSK1) is directly activated by MAPK and SAPK2/p38, and may mediate activation of CREB
    • Deak, M., Clifton, A. D., Lucocq, J. M. & Alessi, D. R. Mitogen-and stress-activated protein kinase-1 (MSK1) is directly activated by MAPK and SAPK2/p38, and may mediate activation of CREB. EMBO J. 17, 4426-4441 (1998).
    • (1998) EMBO J. , vol.17 , pp. 4426-4441
    • Deak, M.1    Clifton, A.D.2    Lucocq, J.M.3    Alessi, D.R.4
  • 18
    • 0029982565 scopus 로고    scopus 로고
    • Characterization of the structure and function of a new mitogen-activated protein kinase (p38beta)
    • Jiang, Y. et al. Characterization of the structure and function of a new mitogen-activated protein kinase (p38beta). J. Biol. Chem. 271, 17920-17926 (1996).
    • (1996) J. Biol. Chem. , vol.271 , pp. 17920-17926
    • Jiang, Y.1
  • 19
    • 0029938805 scopus 로고    scopus 로고
    • Stress-induced phosphorylation and activation of the transcription factor CHOP (GADD153) by p38 MAP kinase
    • Wang, X. Z. & Ron, D. Stress-induced phosphorylation and activation of the transcription factor CHOP (GADD153) by p38 MAP kinase. Science 272, 1347-1349 (1996).
    • (1996) Science , vol.272 , pp. 1347-1349
    • Wang, X.Z.1    Ron, D.2
  • 20
    • 0030894683 scopus 로고    scopus 로고
    • Activation of the transcription factor MEF2C by the MAP kinase p38 in inflammation
    • Han, J., Jiang, Y., Li, Z., Kravchenko, V. V. & Ulevitch, R. J. Activation of the transcription factor MEF2C by the MAP kinase p38 in inflammation. Nature 386, 296-299 (1997).
    • (1997) Nature , vol.386 , pp. 296-299
    • Han, J.1    Jiang, Y.2    Li, Z.3    Kravchenko, V.V.4    Ulevitch, R.J.5
  • 21
    • 0026457201 scopus 로고
    • Identification of MAPKAP kinase 2 as a major enzyme responsible for the phosphorylation of the small mammalian heat shock proteins
    • Stokoe, D., Engel, K., Campbell, D. G., Cohen, P. & Gaestel, M. Identification of MAPKAP kinase 2 as a major enzyme responsible for the phosphorylation of the small mammalian heat shock proteins. FEBS Lett. 313, 307-313 (1992).
    • (1992) FEBS Lett. , vol.313 , pp. 307-313
    • Stokoe, D.1    Engel, K.2    Campbell, D.G.3    Cohen, P.4    Gaestel, M.5
  • 22
    • 0030045453 scopus 로고    scopus 로고
    • Identification of anisomycin-activated kinases p45 and p55 in murine cells as MAPKAP kinase-2
    • Cano, E., Doza, Y. N., Ben-Levy, R., Cohen, P. & Mahadevan, L. C. Identification of anisomycin-activated kinases p45 and p55 in murine cells as MAPKAP kinase-2. Oncogene 12, 805-812 (1996).
    • (1996) Oncogene , vol.12 , pp. 805-812
    • Cano, E.1    Doza, Y.N.2    Ben-Levy, R.3    Cohen, P.4    Mahadevan, L.C.5
  • 23
    • 0000352873 scopus 로고
    • Galactosamine-induced sensitization to the lethal effects of endotoxin
    • Galanos, C., Freudenberg, M. A., & Reutter, W. Galactosamine-induced sensitization to the lethal effects of endotoxin. Proc. Natl Acad. Sci. USA 76, 5939-5943 (1979).
    • (1979) Proc. Natl Acad. Sci. USA , vol.76 , pp. 5939-5943
    • Galanos, C.1    Freudenberg, M.A.2    Reutter, W.3
  • 24
    • 0030685133 scopus 로고    scopus 로고
    • Lipopolysaccharide-binding protein is required to combat a murine gram-negative bacterial infection
    • Jack, R. S. et al. Lipopolysaccharide-binding protein is required to combat a murine gram-negative bacterial infection. Nature 389, 742-745 (1997).
    • (1997) Nature , vol.389 , pp. 742-745
    • Jack, R.S.1
  • 25
    • 0027327619 scopus 로고
    • Mice lacking the tumour necrosis factor receptor 1 are resistant to TNF-mediated toxicity but highly susceptible to infection by Listeria monocytogenes
    • Rothe, J. et al. Mice lacking the tumour necrosis factor receptor 1 are resistant to TNF-mediated toxicity but highly susceptible to infection by Listeria monocytogenes. Nature 364, 798-802 (1993).
    • (1993) Nature , vol.364 , pp. 798-802
    • Rothe, J.1
  • 26
    • 0345609037 scopus 로고    scopus 로고
    • Characterization of tumor necrosis factor-deficient mice
    • Marino, M.W. et al. Characterization of tumor necrosis factor-deficient mice. Proc. Natl Acad. Sci. USA 94, 8093-8098 (1997).
    • (1997) Proc. Natl Acad. Sci. USA , vol.94 , pp. 8093-8098
    • Marino, M.W.1
  • 27
    • 0029991923 scopus 로고    scopus 로고
    • Role of lymphotoxin and the type I TNF receptor in the formation of germinal centers
    • Matsumoto, M. et al. Role of lymphotoxin and the type I TNF receptor in the formation of germinal centers. Science 271, 1289-1291 (1996).
    • (1996) Science , vol.271 , pp. 1289-1291
    • Matsumoto, M.1
  • 28
    • 0020644413 scopus 로고
    • Monensin inhibits initial spreading of cultured human fibroblasts
    • Pizzey, J. A., Bennett, F. A. & Jones, G. E. Monensin inhibits initial spreading of cultured human fibroblasts. Nature 305, 315-317 (1983).
    • (1983) Nature , vol.305 , pp. 315-317
    • Pizzey, J.A.1    Bennett, F.A.2    Jones, G.E.3
  • 29
    • 0032526988 scopus 로고    scopus 로고
    • Leptomycin B-sensitive nuclear export of MAPKAP kinase 2 is regulated by phosphorylation
    • Engel, K., Kotlyarov, A. & Gaestel, M. Leptomycin B-sensitive nuclear export of MAPKAP kinase 2 is regulated by phosphorylation. EMBO J. 17, 3363-3371 (1998).
    • (1998) EMBO J. , vol.17 , pp. 3363-3371
    • Engel, K.1    Kotlyarov, A.2    Gaestel, M.3
  • 30
    • 0032563807 scopus 로고    scopus 로고
    • Nuclear export of the stress-activated protein kinase p38 mediated by its substrate MAPKAP kinase-2
    • Ben-Levy, R., Hooper, S., Wilson, R., Paterson, H. F. & Marshall, C. J. Nuclear export of the stress-activated protein kinase p38 mediated by its substrate MAPKAP kinase-2. Curr. Biol. 8, 1049-1057 (1998).
    • (1998) Curr. Biol. , vol.8 , pp. 1049-1057
    • Ben-Levy, R.1    Hooper, S.2    Wilson, R.3    Paterson, H.F.4    Marshall, C.J.5
  • 31
    • 1842410677 scopus 로고    scopus 로고
    • PMA-induced activation of the p42/44ERK-and p38RK-MAP kinase cascades in HL-60 cells is PKC dependent but not essential for differentiation to the macrophage-like phenotype
    • Schultz, H., Engel, K. & Gaestel, M. PMA-induced activation of the p42/44ERK-and p38RK-MAP kinase cascades in HL-60 cells is PKC dependent but not essential for differentiation to the macrophage-like phenotype. J. Cell. Physiol. 173, 310-318 (1997).
    • (1997) J. Cell. Physiol. , vol.173 , pp. 310-318
    • Schultz, H.1    Engel, K.2    Gaestel, M.3
  • 32
    • 0029030855 scopus 로고
    • ATF-2 is preferentially activated by stress-activated protein kinases to mediate c-jun induction in response to genotoxic agents
    • van Dam, H. et al. ATF-2 is preferentially activated by stress-activated protein kinases to mediate c-jun induction in response to genotoxic agents. EMBO J. 14, 1798-1811 (1995).
    • (1995) EMBO J. , vol.14 , pp. 1798-1811
    • Van Dam, H.1
  • 33
    • 0026497315 scopus 로고
    • Functional and molecular characterization of single, (4-hydroxy-3-nitrophenyl) acetyl (NP)-specific, IgG + B cells from antibody-secreting and memory B cell pathways in the C57BL/6 immune response to NP
    • Lalor, P. A., Nelson, G. J. V., Sanderson, R. D. & McHeyzer-Williams, M. G. Functional and molecular characterization of single, (4-hydroxy-3-nitrophenyl) acetyl (NP)-specific, IgG + B cells from antibody-secreting and memory B cell pathways in the C57BL/6 immune response to NP. Eur. J. Immunol. 22, 3001-3011 (1992).
    • (1992) Eur. J. Immunol. , vol.22 , pp. 3001-3011
    • Lalor, P.A.1    Nelson, G.J.V.2    Sanderson, R.D.3    McHeyzer-Williams, M.G.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.