The p38 MAP kinase pathway signals for cytokine-induced mRNA stabilization via MAP kinase-activated protein kinase 2 and an AU-rich region-targeted mechanism

EMBO Journal

Volumn 18, Issue 18, 1999, Pages 4969-4980

  Winzen, Reinhard ^c   Kracht, Michael ^c   Ritter, Birgit ^c   Wilhelm, Arno ^c   Chen, Chyi Ying A ^a   Shyu, Ann Bin ^a   Müller, Monika ^b   Gaestel, Matthias ^b   Resch, Klaus ^c   Holtmann, Helmut ^d  

^a UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

^b MARTIN LUTHER UNIVERSITY HALLE WITTENBERG   (Germany)

^c HANNOVER MEDICAL SCHOOL   (Germany)

^d NONE

Author keywords

Cytokines; Kinase cascade; MAPKAP kinase 2; mRNA degradation; Signal transduction

Indexed keywords

BETA GLOBIN; CYTOKINE; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 1; INTERLEUKIN 6; INTERLEUKIN 8; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE ACTIVATED PROTEIN KINASE 2; PROTEIN KINASE; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; GENE INDUCTION; HELA CELL; HUMAN; HUMAN CELL; INFLAMMATION; NUCLEOTIDE SEQUENCE; ONCOGENE C FOS; PRIORITY JOURNAL; RNA DEGRADATION; RNA STRUCTURE; RNA TRANSCRIPTION; SIGNAL TRANSDUCTION;

3' UNTRANSLATED REGIONS; BASE SEQUENCE; CYTOKINES; DNA PRIMERS; GENE EXPRESSION; GENES, REPORTER; HELA CELLS; HUMANS; INTERLEUKIN-1; INTERLEUKIN-6; INTERLEUKIN-8; MITOGEN-ACTIVATED PROTEIN KINASES; MOLECULAR SEQUENCE DATA; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PROTEIN-SERINE-THREONINE KINASES; RNA STABILITY; RNA, MESSENGER; SIGNAL TRANSDUCTION; TRANSFECTION;

EID: 0033568608     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/18.18.4969     Document Type: Article

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