Interleukin-10 targets p38 MAPK to modulate ARE-dependent TNF mRNA translation and limit intestinal pathology

EMBO Journal

Volumn 20, Issue 14, 2001, Pages 3760-3770

  Kontoyiannis, Dimitris ^a   Kotlyarov, Alexey ^b   Carballo, Ester ^c   Alexopoulou, Lena ^a,d   Blackshear, Perry J ^c   Gaestel, Matthias ^b   Davis, Roger ^e   Flavell, Richard ^d   Kollias, George ^a  

^a BIOMEDICAL SCIENCES RESEARCH CENTER ALEXANDER FLEMING   (Greece)

^b MARTIN LUTHER UNIVERSITY HALLE WITTENBERG   (Germany)

^c NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^d YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

Author keywords

Animal model; Anti inflammatory; Crohn's disease; Gene expression; Knockout

Indexed keywords

BINDING PROTEIN; INTERLEUKIN 10; INTERLEUKIN 10 RECEPTOR; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE; STRESS ACTIVATED PROTEIN KINASE; SYNAPTOPHYSIN; TRISTETRAPROLIN; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENTERITIS; ENTEROPATHY; IMMUNE SYSTEM; INFLAMMATION; MOUSE; MUCOSAL IMMUNITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN STABILITY; RNA TRANSLATION; SIGNAL TRANSDUCTION;

ANIMALS; CELL SEPARATION; ENZYME-LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; INTERLEUKIN-10; INTESTINES; LIPOPOLYSACCHARIDES; MACROPHAGE ACTIVATION; MACROPHAGES; MICE; MICE, KNOCKOUT; MITOGEN-ACTIVATED PROTEIN KINASES; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PROTEIN BIOSYNTHESIS; PROTEIN-SERINE-THREONINE KINASES; RNA, MESSENGER; SUBSTRATE SPECIFICITY; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0035898647     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/20.14.3760     Document Type: Article

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