Decreased Sensitivity of Tristetraprolin-deficient Cells to p38 Inhibitors Suggests the Involvement of Tristetraprolin in the p38 Signaling Pathway

Journal of Biological Chemistry

Volumn 276, Issue 45, 2001, Pages 42580-42587

  Carballo, Ester ^a,b,d   Cao, Heping ^a,b   Lai, Wi S ^a,b   Kennington, Elizabeth A ^a,b   Campbell, Douglas ^c   Blackshear, Perry J ^a,b  

^a NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^b DUKE UNIVERSITY MEDICAL CENTER   (United States)

^c ASTRAZENECA   (United Kingdom)

^d MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; ENZYME IMMOBILIZATION; ENZYME KINETICS; ONCOLOGY; PROTEINS;

PHOSPHORYLATION;

ENZYME INHIBITION;

4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; 5 (2 AMINO 4 PYRIMIDINYL) 4 (4 FLUOROPHENYL) 1 (4 PIPERIDINYL)IMIDAZOLE; CELL PROTEIN; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; IMIDAZOLE DERIVATIVE; LIPOPOLYSACCHARIDE; MESSENGER RNA; PROTEIN KINASE INHIBITOR; PYRIDINE DERIVATIVE; TRISTETRAPROLIN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; DNA BINDING PROTEIN; ENZYME INHIBITOR; HYBRID PROTEIN; IMMEDIATE EARLY PROTEIN; INTERLEUKIN 3; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; ZFP36 PROTEIN, MOUSE;

3' UNTRANSLATED REGION; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; CYTOKINE RELEASE; DEPHOSPHORYLATION; DRUG SENSITIVITY; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; INFLAMMATION; MACROPHAGE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RNA PROBE; RNA STABILITY; SIGNAL TRANSDUCTION; ANIMAL; BIOSYNTHESIS; DRUG ANTAGONISM; GENETICS; METABOLISM; MOUSE MUTANT; PHOSPHORYLATION; PHYSIOLOGY;

ANIMALIA; MAMMALIA;

3' UNTRANSLATED REGIONS; ANIMALS; DNA-BINDING PROTEINS; ENZYME INHIBITORS; IMMEDIATE-EARLY PROTEINS; INTERLEUKIN-3; MACROPHAGES; MICE; MICE, KNOCKOUT; MITOGEN-ACTIVATED PROTEIN KINASES; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; RECOMBINANT FUSION PROTEINS; RNA, MESSENGER; TRISTETRAPROLIN; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0035834741     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M104953200     Document Type: Article

References (43)

1. Xu, N., Chen, C. Y., and Shyu, A. B. (1997) Mol. Cell. Biol. 17, 4611-4621
2. Dean, J. L., Wait, R., Mahtani, K. R., Sully, G., Clark, A. R., and Saklatvala, J. (2001) Mol. Cell. Biol. 21, 721-730
3. Piecyk, M., Wax, S., Beck, A. R., Kedersha, N., Gupta, M., Maritim, B., Chen, S., Gueydan, C., Kruys, V., Streuli, M., and Anderson, P. (2000) EMBO J. 19, 4154-4163
4. Kontoyiannis, D., Pasparakis, M., Pizarro, T. T., Cominelli, F., and Kollias, G. (1999) Immunity 10, 387-398
5. Brook, M., Sully, G., Clark, A. R., and Saklatvala, J. (2000) FEBS Lett. 483, 57-61
6. Wang, S. W., Pawlowski, J., Wathen, S. T., Kinney, S. D., Lichenstein, H. S., and Manthey, C. L. (1999) Inflamm. Res. 48, 533-538
7. Badger, A. M., Bradbeer, J. N., Votta, B., Lee, J. C., Adams, J. L., and Griswold, D. E. (1996) J. Pharmacol. Exp. Ther. 279, 1453-1461
8. Prichett, W., Hand, A., Sheilds, J., and Dunnington, D. (1995) J. Inflamm. 45, 97-105
9. Young, P., McDonnell, P., Dunnington, D., Hand, A., Laydon, J., and Lee, J. (1993) Agents Actions 39, C67-C69
10. Lee, J. C., Laydon, J. T., McDonnell, P. C., Gallagher, T. F., Kumar, S., Green, D., McNulty, D., Blumenthal, M. J., Heys, J. R., Landvatter, S. W., Strickler, J. E., McLaughlin, M. M., Siemens, I. R., Fisher, S. M., Livi, G. P. White, J. R., Adams, J. L., and Young, P. R. (1994) Nature 372, 739-746
11. Kotlyarov, A., Neininger, A., Schubert, C., Eckert, R., Birchmeier, C., Volk, H. D., and Gaestel, M. (1999) Nat. Cell Biol. 1, 94-97
12. Obata, T., Brown, G. E., and Yaffe, M. B. (2000) Crit. Care Med. 28, N67-N77
13. Waskiewicz, A. J., and Cooper, J. A. (1995) Curr. Opin. Cell Biol. 7, 798-805
14. Herlaar, E., and Brown, Z. (1999) Mol. Med. Today 5, 439-447
15. Carballo, E., Lai, W. S., and Blackshear, P. J. (1998) Science 281, 1001-1005
16. Taylor, G. A., Carballo, E., Lee, D. M., Lai, W. S., Thompson, M. J., Patel, D. D., Schenkman, D. I., Gilkeson, G. S., Broxmeyer, H. E., Haynes, B. F., and Blackshear, P. J. (1996) Immunity 4, 445-454
17. Carballo, E., Gilkeson, G. S., and Blackshear, P. J. (1997) J. Clin. Invest. 100, 986-995
18. Carballo, E., Lai, W. S., and Blackshear, P. J. (2000) Blood 95, 1891-1899
19. Taylor, G. A., Thompson, M. J., Lai, W. S., and Blackshear, P. J. (1995) J. Biol. Chem. 270, 13341-13347
20. Jackson, J. R., Bolognese, B., Hillegass, L., Kassis, S., Adams, J., Griswold, D. E., and Winkler, J. D. (1998) J. Pharmacol. Exp. Ther. 284, 687-692
21. Barlaam, B., Bird, T. G., Lambert-Van Der Brempt, C., Campbell, D., Foster, S. J., and Maciewicz, R. (1999) J. Med. Chem. 42, 4890-4908
22. Paine, E., Palmantier, R., Akiyama, S. K., Olden, K., and Roberts, J. D. (2000) J. Biol. Chem. 275, 11284-11290
23. Maina, C. V., Riggs, P. D., Grandea, A. G., Slatko, B. E., Moran, L. S., Tagliamonte, J. A., McReynolds, L. A., and Guan, C. D. (1988) Gene (Amst.) 74, 365-373
24. Lai, W. S., Carballo, E., Strum, J. R., Kennington, E. A., Phillips, R. S., and Blackshear, P. J. (1999) Mol. Cell. Biol. 19, 4311-4323
25. Lai, W. S., Thompson, M. J., and Blackshear, P. J. (1998) J. Biol. Chem. 273, 506-517
26. Lai, W. S., Carballo, E., Thorn, J. M., Kennington, E. A., and Blackshear, P. J. (2000) J. Biol. Chem. 275, 17827-17837
27. van den Blink, B., Juffermans, N. P., ten Hove, T., Schultz, M. J., van Deventer, S. J., van der Poll, T., and Peppelenbosch, M. P. (2001) J. Immunol. 166, 582-587
28. Wadsworth, S. A., Cavender, D. E., Beers, S. A., Lalan, P., Schafer, P. H., Malloy, E. A., Wu, W., Fahmy, B., Olini, G. C., Davis, J. E., Pellegrino-Gensey, J. L., Wachter, M. P., and Siekierka, J. J. (1999) J. Pharmacol. Exp. Ther. 291, 680-687
29. Winzen, R., Kracht, M., Ritter, B., Wilhelm, A., Chen, C. Y., Shyu, A. B., Muller, M., Gaestel, M., Resch, K., and Holtmann, H. (1999) EMBO J. 18, 4969-4980
30. Clerk, A., and Sugden, P. H. (1998) FEBS Lett. 426, 93-96
31. Whitmarsh, A. J., Yang, S. H., Su, M. S., Sharrocks, A. D., and Davis, R. J. (1997) Mol. Cell. Biol. 17, 2360-2371
32. Glaser, K. B., Pease, L., Li, J., and Morgan, D. W. (1999) Biochem. Pharmacol. 57, 291-302
33. Hale, K. K., Trollinger, D., Rihanek, M., and Manthey, C. L. (1999) J. Immunol. 162, 4246-4252
34. Kumar, S., McDonnell, P. C., Gum, R. J., Hand, A. T., Lee, J. C., and Young, P. R. (1997) Biochem. Biophys. Res. Commun. 235, 533-538
35. Holtmann, H., Winzen, R., Holland, P., Eickemeier, S., Hoffmann, E., Wallach, D., Malinin, N. L., Cooper, J. A., Resch, K., and Kracht, M. (1999) Mol. Cell. Biol. 19, 6742-6753
36. Beyaert, R., Cuenda, A., Vanden Berghe, W., Plaisance, S., Lee, J. C., Haegeman, G., Cohen, P., and Fiers, W. (1996) EMBO J. 15, 1914-1923
37. Chin, J., and Kostura, M. J. (1993) J. Immunol. 151, 5574-5585
38. Taylor, G. A., Thompson, M. J., Lai, W. S., and Blackshear, P. J. (1996) Mol. Endocrinol. 10, 140-146
39. Ben-Levy, R., Hooper, S., Wilson, R., Paterson, H. F., and Marshall, C. J. (1998) Curr. Biol. 8, 1049-1057
40. Zhu, W., Brauchle, M. A., Di Padova, F., Gram, H., New, L., Ono, K., Downey, J. S., and Han, J. (2001) Am. J. Physiol. 281, L499-L508
41. Ming, X. F., Stoecklin, G., Lu, M., Looser, R., and Moroni, C. (2001) Mol. Cell. Biol. 21, 5778-5789
42. Stoecklin, G., Ming, X. F., Looser, R., and Moroni, C. (2000) Mol. Cell. Biol. 20, 3753-3763
43. Kontoyiannis, D., Kotlyarov, A., Carballo, E., Alexopoulou, L., Blackshear, P. J., Gaestel, M., Davis, R., Flavell, R., and Kollias, G. (2001) EMBO J. 20, 3760-3770