-
1
-
-
2342547059
-
Ribosome formation from subunits studied by stopped-flow and Rayleigh light scattering
-
. .
-
Antoun A. Pavlov M.Y. Tenson T. Ehrenberg M.M. 2004 Ribosome formation from subunits studied by stopped-flow and Rayleigh light scattering. Biol Proced Online 6 35 54.
-
(2004)
Biol Proced Online
, vol.6
, pp. 35-54
-
-
Antoun, A.1
Pavlov, M.Y.2
Tenson, T.3
Ehrenberg, M.M.4
-
2
-
-
3042810717
-
Comparison of tetracycline and tigecycline binding to ribosomes mapped by dimethylsulphate and drug-directed Fe2+ cleavage of 16S rRNA
-
.
-
Bauer G. Berens C. Projan S.J. Hillen W. 2004 Comparison of tetracycline and tigecycline binding to ribosomes mapped by dimethylsulphate and drug-directed Fe2+ cleavage of 16S rRNA. J Antimicrob Chemother 53 592 599.
-
(2004)
J Antimicrob Chemother
, vol.53
, pp. 592-599
-
-
Bauer, G.1
Berens, C.2
Projan, S.J.3
Hillen, W.4
-
3
-
-
0035957387
-
A novel site of antibiotic action in the ribosome: Interaction of evernimicin with the large ribosomal subunit
-
.
-
Belova L. Tenson T. Xiong L. McNicholas P.M. Mankin A.S. 2001 A novel site of antibiotic action in the ribosome: interaction of evernimicin with the large ribosomal subunit. Proc Natl Acad Sci USA 98 3726 3731.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 3726-3731
-
-
Belova, L.1
Tenson, T.2
Xiong, L.3
McNicholas, P.M.4
Mankin, A.S.5
-
8
-
-
0842263829
-
Oxazolidinones: Activity, mode of action, and mechanism of resistance
-
.
-
Bozdogan B. Appelbaum P.C. 2004 Oxazolidinones: activity, mode of action, and mechanism of resistance. Int J Antimicrob Agents 23 113 119.
-
(2004)
Int J Antimicrob Agents
, vol.23
, pp. 113-119
-
-
Bozdogan, B.1
Appelbaum, P.C.2
-
9
-
-
0034704217
-
The structural basis for the action of the antibiotics tetracycline, pactamycin, and hygromycin B on the 30S ribosomal subunit
-
. Jr
-
Brodersen D.E. Clemons W.M. Jr Carter A.P. Morgan-Warren R.J. Wimberly B.T. Ramakrishnan V. 2000 The structural basis for the action of the antibiotics tetracycline, pactamycin, and hygromycin B on the 30S ribosomal subunit. Cell 103 1143 1154.
-
(2000)
Cell
, vol.103
, pp. 1143-1154
-
-
Brodersen, D.E.1
Clemons, W.M.2
Carter, A.P.3
Morgan-Warren, R.J.4
Wimberly, B.T.5
Ramakrishnan, V.6
-
10
-
-
0034583884
-
Ketolides-telithromycin, an example of a new class of antibacterial agents
-
.
-
Bryskier A. 2000 Ketolides-telithromycin, an example of a new class of antibacterial agents. Clin Microbiol Infect 6 661 669.
-
(2000)
Clin Microbiol Infect
, vol.6
, pp. 661-669
-
-
Bryskier, A.1
-
12
-
-
0029991408
-
50S ribosomal subunit synthesis and translation are equivalent targets for erythromycin inhibition in Staphylococcus aureus
-
.
-
Champney W.S. Burdine R. 1996 50S ribosomal subunit synthesis and translation are equivalent targets for erythromycin inhibition in Staphylococcus aureus. Antimicrob Agents Chemother 40 1301 1303.
-
(1996)
Antimicrob Agents Chemother
, vol.40
, pp. 1301-1303
-
-
Champney, W.S.1
Burdine, R.2
-
13
-
-
0036617086
-
Inhibition of 50S ribosomal subunit assembly in Haemophilus influenzae cells by azithromycin and erythromycin
-
.
-
Champney W.S. Miller M. 2002a Inhibition of 50S ribosomal subunit assembly in Haemophilus influenzae cells by azithromycin and erythromycin. Curr Microbiol 44 418 424.
-
(2002)
Curr Microbiol
, vol.44
, pp. 418-424
-
-
Champney, W.S.1
Miller, M.2
-
14
-
-
0036582340
-
Linezolid is a specific inhibitor of 50S ribosomal subunit formation in Staphylococcus aureus cells
-
.
-
Champney W.S. Miller M. 2002b Linezolid is a specific inhibitor of 50S ribosomal subunit formation in Staphylococcus aureus cells. Curr Microbiol 44 350 356.
-
(2002)
Curr Microbiol
, vol.44
, pp. 350-356
-
-
Champney, W.S.1
Miller, M.2
-
15
-
-
0041671051
-
A 50S ribosomal subunit precursor particle is a substrate for the ErmC methyltransferase in Staphylococcus aureus cells
-
.
-
Champney W.S. Chittum H.S. Tober C.L. 2003 A 50S ribosomal subunit precursor particle is a substrate for the ErmC methyltransferase in Staphylococcus aureus cells. Curr Microbiol 46 453 460.
-
(2003)
Curr Microbiol
, vol.46
, pp. 453-460
-
-
Champney, W.S.1
Chittum, H.S.2
Tober, C.L.3
-
17
-
-
23044445236
-
Features of ribosome-peptidyl-tRNA interactions essential for tryptophan induction of tna operon expression
-
.
-
Cruz-Vera L.R. Rajagopal S. Squires C. Yanofsky C. 2005 Features of ribosome-peptidyl-tRNA interactions essential for tryptophan induction of tna operon expression. Mol Cell 19 333 343.
-
(2005)
Mol Cell
, vol.19
, pp. 333-343
-
-
Cruz-Vera, L.R.1
Rajagopal, S.2
Squires, C.3
Yanofsky, C.4
-
19
-
-
0018127586
-
Antibiotic susceptibility of the peptidyl transferase locus of bovine mitochondrial ribosomes
-
.
-
Denslow N.D. O'Brien T.W. 1978 Antibiotic susceptibility of the peptidyl transferase locus of bovine mitochondrial ribosomes. Eur J Biochem 91 441 448.
-
(1978)
Eur J Biochem
, vol.91
, pp. 441-448
-
-
Denslow, N.D.1
O'Brien, T.W.2
-
20
-
-
1642564526
-
Dissecting the ribosomal inhibition mechanisms of edeine and pactamycin: The universally conserved residues G693 and C795 regulate P-site RNA binding
-
.
-
Dinos G. Wilson D.N. Teraoka Y. Szaflarski W. Fucini P. Kalpaxis D. Nierhaus K.H. 2004 Dissecting the ribosomal inhibition mechanisms of edeine and pactamycin: the universally conserved residues G693 and C795 regulate P-site RNA binding. Mol Cell 13 113 124.
-
(2004)
Mol Cell
, vol.13
, pp. 113-124
-
-
Dinos, G.1
Wilson, D.N.2
Teraoka, Y.3
Szaflarski, W.4
Fucini, P.5
Kalpaxis, D.6
Nierhaus, K.H.7
-
21
-
-
0025912716
-
Lack of complete cooperativity of ribosome assembly in vitro and its possible relevance to in vivo ribosome assembly and the regulation of ribosomal gene expression
-
.
-
Dodd J. Kolb J.M. Nomura M. 1991 Lack of complete cooperativity of ribosome assembly in vitro and its possible relevance to in vivo ribosome assembly and the regulation of ribosomal gene expression. Biochimie 73 757 767.
-
(1991)
Biochimie
, vol.73
, pp. 757-767
-
-
Dodd, J.1
Kolb, J.M.2
Nomura, M.3
-
22
-
-
1842471295
-
The tylosin-resistance methyltransferase RlmA(II) (TlrB) modifies the N-1 position of 23S rRNA nucleotide G748
-
.
-
Douthwaite S. Crain P.F. Liu M. Poehlsgaard J. 2004 The tylosin-resistance methyltransferase RlmA(II) (TlrB) modifies the N-1 position of 23S rRNA nucleotide G748. J Mol Biol 337 1073 1077.
-
(2004)
J Mol Biol
, vol.337
, pp. 1073-1077
-
-
Douthwaite, S.1
Crain, P.F.2
Liu, M.3
Poehlsgaard, J.4
-
23
-
-
26944438340
-
Ketolide resistance in Streptococcus pyogenes correlates with the degree of rRNA dimethylation by Erm
-
.
-
Douthwaite S. Jalava J. Jakobsen L. 2005 Ketolide resistance in Streptococcus pyogenes correlates with the degree of rRNA dimethylation by Erm. Mol Microbiol 58 613 622.
-
(2005)
Mol Microbiol
, vol.58
, pp. 613-622
-
-
Douthwaite, S.1
Jalava, J.2
Jakobsen, L.3
-
24
-
-
0021305839
-
Translational attenuation: The regulation of bacterial resistance to the macrolide-lincosamide-streptogramin B antibiotics
-
.
-
Dubnau D. 1984 Translational attenuation: the regulation of bacterial resistance to the macrolide-lincosamide-streptogramin B antibiotics. CRC Crit Rev Biochem 16 103 132.
-
(1984)
CRC Crit Rev Biochem
, vol.16
, pp. 103-132
-
-
Dubnau, D.1
-
25
-
-
0035317875
-
Mechanism-related changes in the gene transcription and protein synthesis patterns of Haemophilus influenzae after treatment with transcriptional and translational inhibitors
-
.
-
Evers S. Di Padova K. Meyer M. Langen H. Fountoulakis M. Keck W. Gray C.P. 2001 Mechanism-related changes in the gene transcription and protein synthesis patterns of Haemophilus influenzae after treatment with transcriptional and translational inhibitors. Proteomics 1 522 544.
-
(2001)
Proteomics
, vol.1
, pp. 522-544
-
-
Evers, S.1
Di Padova, K.2
Meyer, M.3
Langen, H.4
Fountoulakis, M.5
Keck, W.6
Gray, C.P.7
-
27
-
-
0347766000
-
Identification of antibiotic stress-inducible promoters: A systematic approach to novel pathway-specific reporter assays for antibacterial drug discovery
-
.
-
Fischer H.P. Brunner N.A. Wieland B. Paquette J. Macko L. Ziegelbauer K. Freiberg C. 2004 Identification of antibiotic stress-inducible promoters: a systematic approach to novel pathway-specific reporter assays for antibacterial drug discovery. Genome Res 14 90 98.
-
(2004)
Genome Res
, vol.14
, pp. 90-98
-
-
Fischer, H.P.1
Brunner, N.A.2
Wieland, B.3
Paquette, J.4
MacKo, L.5
Ziegelbauer, K.6
Freiberg, C.7
-
28
-
-
0029825658
-
Structure of the a site of Escherichia coli 16S ribosomal RNA complexed with an aminoglycoside antibiotic
-
.
-
Fourmy D. Recht M.I. Blanchard S.C. Puglisi J.D. 1996 Structure of the A site of Escherichia coli 16S ribosomal RNA complexed with an aminoglycoside antibiotic. Science 274 1367 1371.
-
(1996)
Science
, vol.274
, pp. 1367-1371
-
-
Fourmy, D.1
Recht, M.I.2
Blanchard, S.C.3
Puglisi, J.D.4
-
29
-
-
27244458194
-
Crystal structures of complexes between aminoglycosides and decoding a site oligonucleotides: Role of the number of rings and positive charges in the specific binding leading to miscoding
-
.
-
Francois B. Russell R.J. Murray J.B. Aboul-ela F. Masquida B. Vicens Q. Westhof E. 2005 Crystal structures of complexes between aminoglycosides and decoding A site oligonucleotides: role of the number of rings and positive charges in the specific binding leading to miscoding. Nucleic Acids Res 33 5677 5690.
-
(2005)
Nucleic Acids Res
, vol.33
, pp. 5677-5690
-
-
Francois, B.1
Russell, R.J.2
Murray, J.B.3
Aboul-Ela, F.4
Masquida, B.5
Vicens, Q.6
Westhof, E.7
-
30
-
-
0030949960
-
Release factor RF3 in E. coli accelerates the dissociation of release factors RF1 and RF2 from the ribosome in a GTP-dependent manner
-
.
-
Freistroffer D.V. Pavlov M.Y. MacDougall J. Buckingham R.H. Ehrenberg M. 1997 Release factor RF3 in E. coli accelerates the dissociation of release factors RF1 and RF2 from the ribosome in a GTP-dependent manner. EMBO J 16 4126 4133.
-
(1997)
EMBO J
, vol.16
, pp. 4126-4133
-
-
Freistroffer, D.V.1
Pavlov, M.Y.2
MacDougall, J.3
Buckingham, R.H.4
Ehrenberg, M.5
-
31
-
-
0035162904
-
Binding site of macrolide antibiotics on the ribosome: New resistance mutation identifies a specific interaction of ketolides with rRNA
-
.
-
Garza-Ramos G. Xiong L. Zhong P. Mankin A. 2001 Binding site of macrolide antibiotics on the ribosome: new resistance mutation identifies a specific interaction of ketolides with rRNA. J Bacteriol 183 6898 6907.
-
(2001)
J Bacteriol
, vol.183
, pp. 6898-6907
-
-
Garza-Ramos, G.1
Xiong, L.2
Zhong, P.3
Mankin, A.4
-
32
-
-
0037168560
-
Transcriptional modulation of bacterial gene expression by subinhibitory concentrations of antibiotics
-
.
-
Goh E.B. Yim G. Tsui W. McClure J. Surette M.G. Davies J. 2002 Transcriptional modulation of bacterial gene expression by subinhibitory concentrations of antibiotics. Proc Natl Acad Sci USA 99 17025 17030.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 17025-17030
-
-
Goh, E.B.1
Yim, G.2
Tsui, W.3
McClure, J.4
Surette, M.G.5
Davies, J.6
-
33
-
-
1842420639
-
Streptomycin interferes with conformational coupling between codon recognition and GTPase activation on the ribosome
-
.
-
Gromadski K.B. Rodnina M.V. 2004 Streptomycin interferes with conformational coupling between codon recognition and GTPase activation on the ribosome. Nat Struct Mol Biol 11 316 322.
-
(2004)
Nat Struct Mol Biol
, vol.11
, pp. 316-322
-
-
Gromadski, K.B.1
Rodnina, M.V.2
-
34
-
-
0032950956
-
The macrolide-ketolide antibiotic binding site is formed by structures in domains II and V of 23S ribosomal RNA
-
.
-
Hansen L.H. Mauvais P. Douthwaite S. 1999 The macrolide-ketolide antibiotic binding site is formed by structures in domains II and V of 23S ribosomal RNA. Mol Microbiol 31 623 631.
-
(1999)
Mol Microbiol
, vol.31
, pp. 623-631
-
-
Hansen, L.H.1
Mauvais, P.2
Douthwaite, S.3
-
35
-
-
0035958741
-
Recognition of nucleotide G745 in 23S ribosomal RNA by the rrmA methyltransferase
-
.
-
Hansen L.H. Kirpekar F. Douthwaite S. 2001 Recognition of nucleotide G745 in 23S ribosomal RNA by the rrmA methyltransferase. J Mol Biol 310 1001 1010.
-
(2001)
J Mol Biol
, vol.310
, pp. 1001-1010
-
-
Hansen, L.H.1
Kirpekar, F.2
Douthwaite, S.3
-
37
-
-
0038013670
-
Structures of five antibiotics bound at the peptidyl transferase center of the large ribosomal subunit
-
.
-
Hansen J.L. Moore P.B. Steitz T.A. 2003 Structures of five antibiotics bound at the peptidyl transferase center of the large ribosomal subunit. J Mol Biol 330 1061 1075.
-
(2003)
J Mol Biol
, vol.330
, pp. 1061-1075
-
-
Hansen, J.L.1
Moore, P.B.2
Steitz, T.A.3
-
38
-
-
0035977093
-
High resolution structure of the large ribosomal subunit from a mesophilic eubacterium
-
.
-
Harms J. Schluenzen F. Zarivach R. Bashan A. Gat S. Agmon I. et al. 2001 High resolution structure of the large ribosomal subunit from a mesophilic eubacterium. Cell 107 679 688.
-
(2001)
Cell
, vol.107
, pp. 679-688
-
-
Harms, J.1
Schluenzen, F.2
Zarivach, R.3
Bashan, A.4
Gat, S.5
Agmon, I.6
-
40
-
-
33645472689
-
-
. In Program and Abstracts of the 45th Interscience Conference on Antimicrobial Agents and Chemotherapy. American Society for Microbiology Washington, DC abst. F-1254.
-
Ippolito J. Kanyo Z. Wimberly B. Wang D. Skripkin E. Devito J. et al. 2005 Structural basis for the binding Rx-01, a novel oxazolidinone class, to bacterial ribosomes. In Program and Abstracts of the 45th Interscience Conference on Antimicrobial Agents and Chemotherapy. Washington, DC American Society for Microbiology abst. F-1254.
-
(2005)
Structural Basis for the Binding Rx-01, a Novel Oxazolidinone Class, to Bacterial Ribosomes
-
-
Ippolito, J.1
Kanyo, Z.2
Wimberly, B.3
Wang, D.4
Skripkin, E.5
Devito, J.6
-
41
-
-
0141925696
-
Disorders of mitochondrial protein synthesis
-
.
-
Jacobs H.T. 2003 Disorders of mitochondrial protein synthesis. Hum Mol Genet 12 Spec No 2 R293 R301.
-
(2003)
Hum Mol Genet
, vol.12
, Issue.2 SPEC. NO.
-
-
Jacobs, H.T.1
-
42
-
-
0023993221
-
Translational attenuation control of ermSF, an inducible resistance determinant encoding rRNA N-methyltransferase from Streptomyces fradiae
-
.
-
Kamimiya S. Weisblum B. 1988 Translational attenuation control of ermSF, an inducible resistance determinant encoding rRNA N-methyltransferase from Streptomyces fradiae. J Bacteriol 170 1800 1811.
-
(1988)
J Bacteriol
, vol.170
, pp. 1800-1811
-
-
Kamimiya, S.1
Weisblum, B.2
-
43
-
-
0033584879
-
Resistance mutations in 23S rRNA identify the site of action of the protein synthesis inhibitor linezolid in the ribosomal peptidyl transferase center
-
.
-
Kloss P. Xiong L. Shinabarger D.L. Mankin A.S. 1999 Resistance mutations in 23S rRNA identify the site of action of the protein synthesis inhibitor linezolid in the ribosomal peptidyl transferase center. J Mol Biol 294 93 101.
-
(1999)
J Mol Biol
, vol.294
, pp. 93-101
-
-
Kloss, P.1
Xiong, L.2
Shinabarger, D.L.3
Mankin, A.S.4
-
44
-
-
0034885097
-
Hematologic effects of antimicrobials: Focus on the oxazolidinone linezolid
-
.
-
Kuter D.J. Tillotson G.S. 2001 Hematologic effects of antimicrobials: focus on the oxazolidinone linezolid. Pharmacotherapy 21 1010 1013.
-
(2001)
Pharmacotherapy
, vol.21
, pp. 1010-1013
-
-
Kuter, D.J.1
Tillotson, G.S.2
-
46
-
-
33645466718
-
-
. In Program and Abstracts of the 45th Interscience Conference on Antimicrobial Agents and Chemotherapy. American Society for Microbiology Washington, DC abst. F-1256.
-
Lawrence L. Sutcliffe J. 2005 In vitro activity of designer oxazolidinones against respiratory pathogens. In Program and Abstracts of the 45th Interscience Conference on Antimicrobial Agents and Chemotherapy. Washington, DC American Society for Microbiology abst. F-1256.
-
(2005)
In Vitro Activity of Designer Oxazolidinones Against Respiratory Pathogens
-
-
Lawrence, L.1
Sutcliffe, J.2
-
47
-
-
20344407298
-
Mutational analysis of the mitochondrial 12S rRNA gene in Chinese pediatric subjects with aminoglycoside-induced and non-syndromic hearing loss
-
.
-
Li Z. Li R. Chen J. Liao Z. Zhu Y. Qian Y. et al. 2005 Mutational analysis of the mitochondrial 12S rRNA gene in Chinese pediatric subjects with aminoglycoside-induced and non-syndromic hearing loss. Hum Genet 117 9 15.
-
(2005)
Hum Genet
, vol.117
, pp. 9-15
-
-
Li, Z.1
Li, R.2
Chen, J.3
Liao, Z.4
Zhu, Y.5
Qian, Y.6
-
48
-
-
0942290554
-
Ribosomal alterations contribute to bacterial resistance against the dipeptide antibiotic TAN 1057
-
.
-
Limburg E. Gahlmann R. Kroll H.P. Beyer D. 2004 Ribosomal alterations contribute to bacterial resistance against the dipeptide antibiotic TAN 1057. Antimicrob Agents Chemother 48 619 622.
-
(2004)
Antimicrob Agents Chemother
, vol.48
, pp. 619-622
-
-
Limburg, E.1
Gahlmann, R.2
Kroll, H.P.3
Beyer, D.4
-
49
-
-
0030773903
-
The oxazolidinone eperezolid binds to the 50S ribosomal subunit and competes with binding of chloramphenicol and lincomycin
-
.
-
Lin A.H. Murray R.W. Vidmar T.J. Marotti K.R. 1997 The oxazolidinone eperezolid binds to the 50S ribosomal subunit and competes with binding of chloramphenicol and lincomycin. Antimicrob Agents Chemother 41 2127 2131.
-
(1997)
Antimicrob Agents Chemother
, vol.41
, pp. 2127-2131
-
-
Lin, A.H.1
Murray, R.W.2
Vidmar, T.J.3
Marotti, K.R.4
-
50
-
-
0037069328
-
Resistance to the macrolide antibiotic tylosin is conferred by single methylations at 23S rRNA nucleotides G748 and A2058 acting in synergy
-
.
-
Liu M. Douthwaite S. 2002 Resistance to the macrolide antibiotic tylosin is conferred by single methylations at 23S rRNA nucleotides G748 and A2058 acting in synergy. Proc Natl Acad Sci USA 99 14658 14663.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 14658-14663
-
-
Liu, M.1
Douthwaite, S.2
-
51
-
-
0029982204
-
Ribosome regulation by the nascent peptide
-
.
-
Lovett P.S. Rogers E.J. 1996 Ribosome regulation by the nascent peptide. Microbiol Rev 60 366 385.
-
(1996)
Microbiol Rev
, vol.60
, pp. 366-385
-
-
Lovett, P.S.1
Rogers, E.J.2
-
52
-
-
11144238888
-
Kinetics of macrolide action: The josamycin and erythromycin cases
-
.
-
Lovmar M. Tenson T. Ehrenberg M. 2004 Kinetics of macrolide action: the josamycin and erythromycin cases. J Biol Chem 279 53506 53515.
-
(2004)
J Biol Chem
, vol.279
, pp. 53506-53515
-
-
Lovmar, M.1
Tenson, T.2
Ehrenberg, M.3
-
53
-
-
25444509798
-
TmRNA decreases the bactericidal activity of aminoglycosides and the susceptibility to inhibitors of cell wall synthesis
-
.
-
Luidalepp H. Hallier M. Felden B. Tenson T. 2005 tmRNA decreases the bactericidal activity of aminoglycosides and the susceptibility to inhibitors of cell wall synthesis. RNA Biol 2 70 74.
-
(2005)
RNA Biol
, vol.2
, pp. 70-74
-
-
Luidalepp, H.1
Hallier, M.2
Felden, B.3
Tenson, T.4
-
54
-
-
0037229886
-
Comparison of X-ray crystal structure of the 30S subunit-antibiotic complex with NMR structure of decoding site oligonucleotide-paromomycin complex
-
.
-
Lynch S.R. Gonzalez R.L. Puglisi J.D. 2003 Comparison of X-ray crystal structure of the 30S subunit-antibiotic complex with NMR structure of decoding site oligonucleotide-paromomycin complex. Structure (Camb) 11 43 53.
-
(2003)
Structure (Camb)
, vol.11
, pp. 43-53
-
-
Lynch, S.R.1
Gonzalez, R.L.2
Puglisi, J.D.3
-
55
-
-
20444392722
-
Hyper-susceptibility of a fusidic acid-resistant mutant of Salmonella to different classes of antibiotics
-
.
-
Macvanin M. Hughes D. 2005 Hyper-susceptibility of a fusidic acid-resistant mutant of Salmonella to different classes of antibiotics. FEMS Microbiol Lett 247 215 220.
-
(2005)
FEMS Microbiol Lett
, vol.247
, pp. 215-220
-
-
MacVanin, M.1
Hughes, D.2
-
56
-
-
4644286240
-
Fusidic acid-resistant mutants of Salmonella enterica serovar typhimurium have low levels of heme and a reduced rate of respiration and are sensitive to oxidative stress
-
.
-
Macvanin M. Ballagi A. Hughes D. 2004 Fusidic acid-resistant mutants of Salmonella enterica serovar typhimurium have low levels of heme and a reduced rate of respiration and are sensitive to oxidative stress. Antimicrob Agents Chemother 48 3877 3883.
-
(2004)
Antimicrob Agents Chemother
, vol.48
, pp. 3877-3883
-
-
MacVanin, M.1
Ballagi, A.2
Hughes, D.3
-
58
-
-
27644598282
-
A protein component at the heart of an RNA machine: The importance of protein L27 for the function of the bacterial ribosome
-
.
-
Maguire B.A. Beniaminov A.D. Ramu H. Mankin A.S. Zimmermann R.A. 2005 A protein component at the heart of an RNA machine: the importance of protein L27 for the function of the bacterial ribosome. Mol Cell 20 427 435.
-
(2005)
Mol Cell
, vol.20
, pp. 427-435
-
-
Maguire, B.A.1
Beniaminov, A.D.2
Ramu, H.3
Mankin, A.S.4
Zimmermann, R.A.5
-
59
-
-
0033032414
-
Ribosomal RNA is the target for oxazolidinones, a novel class of translational inhibitors
-
.
-
Matassova N.B. Rodnina M.V. Endermann R. Kroll H.P. Pleiss U. Wild H. Wintermeyer W. 1999 Ribosomal RNA is the target for oxazolidinones, a novel class of translational inhibitors. RNA 5 939 946.
-
(1999)
RNA
, vol.5
, pp. 939-946
-
-
Matassova, N.B.1
Rodnina, M.V.2
Endermann, R.3
Kroll, H.P.4
Pleiss, U.5
Wild, H.6
Wintermeyer, W.7
-
60
-
-
0043026695
-
Neomycin and paromomycin inhibit 30S ribosomal subunit assembly in Staphylococcus aureus
-
.
-
Mehta R. Champney W.S. 2003 Neomycin and paromomycin inhibit 30S ribosomal subunit assembly in Staphylococcus aureus. Curr Microbiol 47 237 243.
-
(2003)
Curr Microbiol
, vol.47
, pp. 237-243
-
-
Mehta, R.1
Champney, W.S.2
-
61
-
-
4744364598
-
Antimicrobial resistance to linezolid
-
.
-
Meka V.G. Gold H.S. 2004 Antimicrobial resistance to linezolid. Clin Infect Dis 39 1010 1015.
-
(2004)
Clin Infect Dis
, vol.39
, pp. 1010-1015
-
-
Meka, V.G.1
Gold, H.S.2
-
62
-
-
3242683097
-
Linezolid resistance in sequential Staphylococcus aureus isolates associated with a T2500A mutation in the 23S rRNA gene and loss of a single copy of rRNA
-
.
-
Meka V.G. Pillai S.K. Sakoulas G. Wennersten C. Venkataraman L. DeGirolami P.C. et al. 2004 Linezolid resistance in sequential Staphylococcus aureus isolates associated with a T2500A mutation in the 23S rRNA gene and loss of a single copy of rRNA. J Infect Dis 190 311 317.
-
(2004)
J Infect Dis
, vol.190
, pp. 311-317
-
-
Meka, V.G.1
Pillai, S.K.2
Sakoulas, G.3
Wennersten, C.4
Venkataraman, L.5
Degirolami, P.C.6
-
63
-
-
0020322533
-
Erythromycin, carbomycin, and spiramycin inhibit protein synthesis by stimulating the dissociation of peptidyl-tRNA from ribosomes
-
.
-
Menninger J.R. Otto D.P. 1982 Erythromycin, carbomycin, and spiramycin inhibit protein synthesis by stimulating the dissociation of peptidyl-tRNA from ribosomes. Antimicrob Agents Chemother 21 811 818.
-
(1982)
Antimicrob Agents Chemother
, vol.21
, pp. 811-818
-
-
Menninger, J.R.1
Otto, D.P.2
-
64
-
-
0037062958
-
The involvement of RNA in ribosome function
-
.
-
Moore P.B. Steitz T.A. 2002 The involvement of RNA in ribosome function. Nature 418 229 235.
-
(2002)
Nature
, vol.418
, pp. 229-235
-
-
Moore, P.B.1
Steitz, T.A.2
-
65
-
-
0035029364
-
Biological cost and compensatory evolution in fusidic acid-resistant Staphylococcus aureus
-
.
-
Nagaev I. Bjorkman J. Andersson D.I. Hughes D. 2001 Biological cost and compensatory evolution in fusidic acid-resistant Staphylococcus aureus. Mol Microbiol 40 433 439.
-
(2001)
Mol Microbiol
, vol.40
, pp. 433-439
-
-
Nagaev, I.1
Bjorkman, J.2
Andersson, D.I.3
Hughes, D.4
-
67
-
-
18844413446
-
Structural insights into translational fidelity
-
.
-
Ogle J.M. Ramakrishnan V. 2005 Structural insights into translational fidelity. Annu Rev Biochem 74 129 177.
-
(2005)
Annu Rev Biochem
, vol.74
, pp. 129-177
-
-
Ogle, J.M.1
Ramakrishnan, V.2
-
69
-
-
0033961143
-
Conformational switch in the decoding region of 16S rRNA during aminoacyl-tRNA selection on the ribosome
-
.
-
Pape T. Wintermeyer W. Rodnina M.V. 2000 Conformational switch in the decoding region of 16S rRNA during aminoacyl-tRNA selection on the ribosome. Nature Struct Biol 7 104 107.
-
(2000)
Nature Struct Biol
, vol.7
, pp. 104-107
-
-
Pape, T.1
Wintermeyer, W.2
Rodnina, M.V.3
-
70
-
-
17044425907
-
23S rRNA base pair 2057-2611 determines ketolide susceptibility and fitness cost of the macrolide resistance mutation 2058A - >g
-
.
-
Pfister P. Corti N. Hobbie S. Bruell C. Zarivach R. Yonath A. Bottger E.C. 2005 23S rRNA base pair 2057-2611 determines ketolide susceptibility and fitness cost of the macrolide resistance mutation 2058A - >G. Proc Natl Acad Sci USA 102 5180 5185.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 5180-5185
-
-
Pfister, P.1
Corti, N.2
Hobbie, S.3
Bruell, C.4
Zarivach, R.5
Yonath, A.6
Bottger, E.C.7
-
71
-
-
0026031835
-
The conformation of nascent polylysine and polyphenylalanine peptides on ribosomes
-
.
-
Picking W.D. Odom O.W. Tsalkova T. Serdyuk I. Hardesty B. 1991 The conformation of nascent polylysine and polyphenylalanine peptides on ribosomes. J Biol Chem 266 1534 1542.
-
(1991)
J Biol Chem
, vol.266
, pp. 1534-1542
-
-
Picking, W.D.1
Odom, O.W.2
Tsalkova, T.3
Serdyuk, I.4
Hardesty, B.5
-
72
-
-
0036786261
-
SPARK - A novel method to monitor ribosomal peptidyl transferase activity
-
.
-
Polacek N. Swaney S. Shinabarger D. Mankin A.S. 2002 SPARK - a novel method to monitor ribosomal peptidyl transferase activity. Biochemistry 41 11602 11610.
-
(2002)
Biochemistry
, vol.41
, pp. 11602-11610
-
-
Polacek, N.1
Swaney, S.2
Shinabarger, D.3
Mankin, A.S.4
-
74
-
-
0141925858
-
Interfering with different steps of protein synthesis explored by transcriptional profiling of Escherichia coli K-12
-
.
-
Sabina J. Dover N. Templeton L.J. Smulski D.R. Soll D. LaRossa R.A. 2003 Interfering with different steps of protein synthesis explored by transcriptional profiling of Escherichia coli K-12. J Bacteriol 185 6158 6170.
-
(2003)
J Bacteriol
, vol.185
, pp. 6158-6170
-
-
Sabina, J.1
Dover, N.2
Templeton, L.J.3
Smulski, D.R.4
Soll, D.5
Larossa, R.A.6
-
75
-
-
0036886952
-
Ribosomal and non-ribosomal resistance to oxazolidinones: Species-specific idiosyncrasy of ribosomal alterations
-
.
-
Sander P. Belova L. Kidan Y.G. Pfister P. Mankin A.S. Bottger E.C. 2002 Ribosomal and non-ribosomal resistance to oxazolidinones: species-specific idiosyncrasy of ribosomal alterations. Mol Microbiol 46 1295 1304.
-
(2002)
Mol Microbiol
, vol.46
, pp. 1295-1304
-
-
Sander, P.1
Belova, L.2
Kidan, Y.G.3
Pfister, P.4
Mankin, A.S.5
Bottger, E.C.6
-
76
-
-
0035950132
-
Structural basis for the interaction of antibiotics with the peptidyl transferase centre in eubacteria
-
.
-
Schlunzen F. Zarivach R. Harms J. Bashan A. Tocilj A. Albrecht R. et al. 2001 Structural basis for the interaction of antibiotics with the peptidyl transferase centre in eubacteria. Nature 413 814 821.
-
(2001)
Nature
, vol.413
, pp. 814-821
-
-
Schlunzen, F.1
Zarivach, R.2
Harms, J.3
Bashan, A.4
Tocilj, A.5
Albrecht, R.6
-
78
-
-
9644281855
-
Inhibition of peptide bond formation by pleuromutilins: The structure of the 50S ribosomal subunit from Deinococcus radiodurans in complex with tiamulin
-
.
-
Schlunzen F. Pyetan E. Fucini P. Yonath A. Harms J.M. 2004 Inhibition of peptide bond formation by pleuromutilins: the structure of the 50S ribosomal subunit from Deinococcus radiodurans in complex with tiamulin. Mol Microbiol 54 1287 1294.
-
(2004)
Mol Microbiol
, vol.54
, pp. 1287-1294
-
-
Schlunzen, F.1
Pyetan, E.2
Fucini, P.3
Yonath, A.4
Harms, J.M.5
-
79
-
-
0036177483
-
A pre-translocational intermediate in protein synthesis observed in crystals of enzymatically active 50S subunits
-
.
-
Schmeing T.M. Seila A.C. Hansen J.L. Freeborn B. Soukup J.K. Scaringe S.A. et al. 2002 A pre-translocational intermediate in protein synthesis observed in crystals of enzymatically active 50S subunits. Nat Struct Biol 9 225 230.
-
(2002)
Nat Struct Biol
, vol.9
, pp. 225-230
-
-
Schmeing, T.M.1
Seila, A.C.2
Hansen, J.L.3
Freeborn, B.4
Soukup, J.K.5
Scaringe, S.A.6
-
80
-
-
21744455460
-
The need for new therapeutic agents: What is the pipeline?
-
Shah P.M. 2005 The need for new therapeutic agents: what is the pipeline? Clin Microbiol Infect 11 Suppl. 3 36 42.
-
(2005)
Clin Microbiol Infect
, vol.11
, Issue.3 SUPPL.
, pp. 36-42
-
-
Shah, P.M.1
-
81
-
-
0035991865
-
Stress-based identification and classification of antibacterial agents: Second-generation Escherichia coli reporter strains and optimization of detection
-
.
-
Shapiro E. Baneyx F. 2002 Stress-based identification and classification of antibacterial agents: second-generation Escherichia coli reporter strains and optimization of detection. Antimicrob Agents Chemother 46 2490 2497.
-
(2002)
Antimicrob Agents Chemother
, vol.46
, pp. 2490-2497
-
-
Shapiro, E.1
Baneyx, F.2
-
83
-
-
0021064473
-
Site of action of a ribosomal RNA methylase responsible for resistance to erythromycin and other antibiotics
-
.
-
Skinner R. Cundliffe E. Schmidt F.J. 1983 Site of action of a ribosomal RNA methylase responsible for resistance to erythromycin and other antibiotics. J Biol Chem 258 12702 12706.
-
(1983)
J Biol Chem
, vol.258
, pp. 12702-12706
-
-
Skinner, R.1
Cundliffe, E.2
Schmidt, F.J.3
-
84
-
-
0029745623
-
Throwing a spanner in the works: Antibiotics and the translation apparatus
-
.
-
Spahn C.M. Prescott C.D. 1996 Throwing a spanner in the works: antibiotics and the translation apparatus. J Mol Med 74 423 439.
-
(1996)
J Mol Med
, vol.74
, pp. 423-439
-
-
Spahn, C.M.1
Prescott, C.D.2
-
85
-
-
25144480034
-
Improving on nature: Antibiotics that target the ribosome
-
.
-
Sutcliffe J.A. 2005 Improving on nature: antibiotics that target the ribosome. Curr Opin Microbiol 8 534 542.
-
(2005)
Curr Opin Microbiol
, vol.8
, pp. 534-542
-
-
Sutcliffe, J.A.1
-
87
-
-
0037040406
-
Regulatory nascent peptides in the ribosomal tunnel
-
.
-
Tenson T. Ehrenberg M. 2002 Regulatory nascent peptides in the ribosomal tunnel. Cell 108 591 594.
-
(2002)
Cell
, vol.108
, pp. 591-594
-
-
Tenson, T.1
Ehrenberg, M.2
-
88
-
-
0029402674
-
Comparison of functional peptide encoded in the Escherichia coli 23S rRNA with other peptides involved in cis-regulation of translation
-
.
-
Tenson T. Mankin A. 1995 Comparison of functional peptide encoded in the Escherichia coli 23S rRNA with other peptides involved in cis-regulation of translation. Biochem Cell Biol 73 1061 1070.
-
(1995)
Biochem Cell Biol
, vol.73
, pp. 1061-1070
-
-
Tenson, T.1
Mankin, A.2
-
89
-
-
0034817784
-
Short peptides conferring resistance to macrolide antibiotics
-
.
-
Tenson T. Mankin A.S. 2001 Short peptides conferring resistance to macrolide antibiotics. Peptides 22 1661 1668.
-
(2001)
Peptides
, vol.22
, pp. 1661-1668
-
-
Tenson, T.1
Mankin, A.S.2
-
90
-
-
0038690158
-
The mechanism of action of macrolides, lincosamides and streptogramin B reveals the nascent peptide exit path in the ribosome
-
.
-
Tenson T. Lovmar M. Ehrenberg M. 2003 The mechanism of action of macrolides, lincosamides and streptogramin B reveals the nascent peptide exit path in the ribosome. J Mol Biol 330 1005 1014.
-
(2003)
J Mol Biol
, vol.330
, pp. 1005-1014
-
-
Tenson, T.1
Lovmar, M.2
Ehrenberg, M.3
-
91
-
-
0036384314
-
The protein synthesis inhibitors, oxazolidinones and chloramphenicol, cause extensive translational inaccuracy in vivo
-
.
-
Thompson J. O'Connor M. Mills J.A. Dahlberg A.E. 2002 The protein synthesis inhibitors, oxazolidinones and chloramphenicol, cause extensive translational inaccuracy in vivo. J Mol Biol 322 273 279.
-
(2002)
J Mol Biol
, vol.322
, pp. 273-279
-
-
Thompson, J.1
O'Connor, M.2
Mills, J.A.3
Dahlberg, A.E.4
-
93
-
-
4644248905
-
Dual effects of MLS antibiotics: Transcriptional modulation and interactions on the ribosome
-
.
-
Tsui W.H. Yim G. Wang H.H. McClure J.E. Surette M.G. Davies J. 2004 Dual effects of MLS antibiotics: transcriptional modulation and interactions on the ribosome. Chem Biol 11 1307 1316.
-
(2004)
Chem Biol
, vol.11
, pp. 1307-1316
-
-
Tsui, W.H.1
Yim, G.2
Wang, H.H.3
McClure, J.E.4
Surette, M.G.5
Davies, J.6
-
94
-
-
17444421169
-
Structures of MLSBK antibiotics bound to mutated large ribosomal subunits provide a structural explanation for resistance
-
.
-
Tu D. Blaha G. Moore P.B. Steitz T.A. 2005 Structures of MLSBK antibiotics bound to mutated large ribosomal subunits provide a structural explanation for resistance. Cell 121 257 270.
-
(2005)
Cell
, vol.121
, pp. 257-270
-
-
Tu, D.1
Blaha, G.2
Moore, P.B.3
Steitz, T.A.4
-
95
-
-
0025328743
-
Ribosomes as sensors of heat and cold shock in Escherichia coli
-
.
-
VanBogelen R.A. Neidhardt F.C. 1990 Ribosomes as sensors of heat and cold shock in Escherichia coli. Proc Natl Acad Sci USA 87 5589 5593.
-
(1990)
Proc Natl Acad Sci USA
, vol.87
, pp. 5589-5593
-
-
Vanbogelen, R.A.1
Neidhardt, F.C.2
-
96
-
-
0035160878
-
Macrolide resistance conferred by base substitutions in 23S rRNA
-
.
-
Vester B. Douthwaite S. 2001 Macrolide resistance conferred by base substitutions in 23S rRNA. Antimicrob Agents Chemother 45 1 12.
-
(2001)
Antimicrob Agents Chemother
, vol.45
, pp. 1-12
-
-
Vester, B.1
Douthwaite, S.2
-
97
-
-
0034886697
-
Crystal structure of paromomycin docked into the eubacterial ribosomal decoding a site
-
.
-
Vicens Q. Westhof E. 2001 Crystal structure of paromomycin docked into the eubacterial ribosomal decoding A site. Structure (Camb) 9 647 658.
-
(2001)
Structure (Camb)
, vol.9
, pp. 647-658
-
-
Vicens, Q.1
Westhof, E.2
-
98
-
-
0037470560
-
Crystal structure of geneticin bound to a bacterial 16S ribosomal RNA a site oligonucleotide
-
.
-
Vicens Q. Westhof E. 2003 Crystal structure of geneticin bound to a bacterial 16S ribosomal RNA A site oligonucleotide. J Mol Biol 326 1175 1188.
-
(2003)
J Mol Biol
, vol.326
, pp. 1175-1188
-
-
Vicens, Q.1
Westhof, E.2
-
99
-
-
6344275448
-
Peptide-mediated macrolide resistance reveals possible specific interactions in the nascent peptide exit tunnel
-
.
-
Vimberg V. Xiong L. Bailey M. Tenson T. Mankin A. 2004 Peptide-mediated macrolide resistance reveals possible specific interactions in the nascent peptide exit tunnel. Mol Microbiol 54 376 385.
-
(2004)
Mol Microbiol
, vol.54
, pp. 376-385
-
-
Vimberg, V.1
Xiong, L.2
Bailey, M.3
Tenson, T.4
Mankin, A.5
-
100
-
-
0028963496
-
Erythromycin resistance by ribosome modification
-
.
-
Weisblum B. 1995a Erythromycin resistance by ribosome modification. Antimicrob Agents Chemother 39 577 585.
-
(1995)
Antimicrob Agents Chemother
, vol.39
, pp. 577-585
-
-
Weisblum, B.1
-
101
-
-
0028914553
-
Insights into erythromycin action from studies of its activity as inducer of resistance
-
.
-
Weisblum B. 1995b Insights into erythromycin action from studies of its activity as inducer of resistance. Antimicrob Agents Chemother 39 797 805.
-
(1995)
Antimicrob Agents Chemother
, vol.39
, pp. 797-805
-
-
Weisblum, B.1
-
102
-
-
29044436081
-
Species-specific antibiotic-ribosome interactions: Implications for drug development
-
.
-
Wilson D.N. Harms J.M. Nierhaus K.H. Schlünzen F. Fucini P. 2005 Species-specific antibiotic-ribosome interactions: implications for drug development. Biol Chem 386 1239 1252.
-
(2005)
Biol Chem
, vol.386
, pp. 1239-1252
-
-
Wilson, D.N.1
Harms, J.M.2
Nierhaus, K.H.3
Schlünzen, F.4
Fucini, P.5
-
103
-
-
0032904341
-
A ketolide resistance mutation in domain II of 23S rRNA reveals the proximity of hairpin 35 to the peptidyl transferase centre
-
.
-
Xiong L. Shah S. Mauvais P. Mankin A.S. 1999 A ketolide resistance mutation in domain II of 23S rRNA reveals the proximity of hairpin 35 to the peptidyl transferase centre. Mol Microbiol 31 633 639.
-
(1999)
Mol Microbiol
, vol.31
, pp. 633-639
-
-
Xiong, L.1
Shah, S.2
Mauvais, P.3
Mankin, A.S.4
-
104
-
-
0033797686
-
Oxazolidinone resistance mutations in 23S rRNA of Escherichia coli reveal the central region of domain V as the primary site of drug action
-
.
-
Xiong L. Kloss P. Douthwaite S. Andersen N.M. Swaney S. Shinabarger D.L. Mankin A.S. 2000 Oxazolidinone resistance mutations in 23S rRNA of Escherichia coli reveal the central region of domain V as the primary site of drug action. J Bacteriol 182 5325 5331.
-
(2000)
J Bacteriol
, vol.182
, pp. 5325-5331
-
-
Xiong, L.1
Kloss, P.2
Douthwaite, S.3
Andersen, N.M.4
Swaney, S.5
Shinabarger, D.L.6
Mankin, A.S.7
-
105
-
-
22244433549
-
Antibiotics targeting ribosomes: Resistance, selectivity, synergism and cellular regulation
-
.
-
Yonath A. 2005 Antibiotics targeting ribosomes: resistance, selectivity, synergism and cellular regulation. Annu Rev Biochem 74 649 679.
-
(2005)
Annu Rev Biochem
, vol.74
, pp. 649-679
-
-
Yonath, A.1
|