Functional insights from the structure of the 30S ribosomal subunit and its interactions with antibiotics

Nature

Volumn 407, Issue 6802, 2000, Pages 340-348

  Carter, Andrew P ^a   Clemons, William M ^a,b   Brodersen, Ditlev E ^a   Morgan Warren, Robert J ^a   Wimberly, Brian T ^a   Ramakrishnan, V ^a  

^a MRC LABORATORY OF MOLECULAR BIOLOGY   (United Kingdom)

^b UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA; PAROMOMYCIN; SPECTINOMYCIN; STREPTOMYCIN;

ANTIMICROBIAL ACTIVITY; ARTICLE; CRYSTAL STRUCTURE; DATA ANALYSIS; GENE EXPRESSION; LIGAND BINDING; PRIORITY JOURNAL; PROTEIN STRUCTURE; PROTEIN SYNTHESIS; RIBOSOME SUBUNIT; RNA TRANSLATION; STRUCTURE ACTIVITY RELATION;

ANTIBIOTICS; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; GENETIC CODE; MACROMOLECULAR SYSTEMS; MODELS, MOLECULAR; MOLECULAR MIMICRY; NUCLEIC ACID CONFORMATION; PAROMOMYCIN; PROTEIN CONFORMATION; RIBOSOMAL PROTEINS; RIBOSOMES; RNA, BACTERIAL; RNA, MESSENGER; RNA, RIBOSOMAL; RNA, RIBOSOMAL, 16S; RNA, TRANSFER; SPECTINOMYCIN; STREPTOMYCIN; STRUCTURE-ACTIVITY RELATIONSHIP; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.; THERMUS THERMOPHILUS;

EID: 0034699519     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/35030019     Document Type: Article

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