-
1
-
-
0036210596
-
Oxazolidinone antibiotics target the P site on Escherichia coli ribosomes
-
Aoki, H., Ke, L., Poppe, S.M., Poel, T.J., Weaver, E.A., Gadwood, R.C., et al. (2002) Oxazolidinone antibiotics target the P site on Escherichia coli ribosomes. Antimicrob Agents Chemother 46: 1080-1085.
-
(2002)
Antimicrob Agents Chemother
, vol.46
, pp. 1080-1085
-
-
Aoki, H.1
Ke, L.2
Poppe, S.M.3
Poel, T.J.4
Weaver, E.A.5
Gadwood, R.C.6
-
2
-
-
0035032997
-
Structural basis for selectivity and toxicity of ribosomal antibiotics
-
Böttger, E.C., Springer, B., Prammananan, T., Kidan, Y., and Sander, P. (2001) Structural basis for selectivity and toxicity of ribosomal antibiotics. EMBO Rep 2: 318-323.
-
(2001)
EMBO Rep
, vol.2
, pp. 318-323
-
-
Böttger, E.C.1
Springer, B.2
Prammananan, T.3
Kidan, Y.4
Sander, P.5
-
3
-
-
0030027833
-
Synthesis and antibacterial activity of U-100592 and U-100766, two oxazolidinone antibacterial agents for the potential treatment of multidrug-resistant gram-positive bacterial infections
-
Brickner, S.J., Hutchinson, D.K., Barachyn, M.R., Manninen, P.R., Ulanowicz, D.A., Garmon, S.A., et al. (1996) Synthesis and antibacterial activity of U-100592 and U-100766, two oxazolidinone antibacterial agents for the potential treatment of multidrug-resistant gram-positive bacterial infections. J Med Chem 39: 673-679.
-
(1996)
J Med Chem
, vol.39
, pp. 673-679
-
-
Brickner, S.J.1
Hutchinson, D.K.2
Barachyn, M.R.3
Manninen, P.R.4
Ulanowicz, D.A.5
Garmon, S.A.6
-
4
-
-
0033674053
-
Clinical and microbiologic efficacy and safety profile of linezolid, a new oxazolidinone antibiotic
-
Corti, G., Cinelli, R., and Paradisi, F. (2000) Clinical and microbiologic efficacy and safety profile of linezolid, a new oxazolidinone antibiotic. Int J Antimicrob Agents 16: 527-530.
-
(2000)
Int J Antimicrob Agents
, vol.16
, pp. 527-530
-
-
Corti, G.1
Cinelli, R.2
Paradisi, F.3
-
5
-
-
0002331708
-
Recognition sites for antibiotics within rRNA
-
Hill, W.E., Dahlberg, A., Garrett, R.A., Moore, P.B., Schlessinger, D., and Warner, J.R. (eds). Washington, DC: American Society for Microbiology Press
-
Cundliffe, E. (1990) Recognition sites for antibiotics within rRNA. In The Ribosome: Structure, Function and Evolution. Hill, W.E., Dahlberg, A., Garrett, R.A., Moore, P.B., Schlessinger, D., and Warner, J.R. (eds). Washington, DC: American Society for Microbiology Press, pp. 479-490.
-
(1990)
The Ribosome: Structure, Function and Evolution
, pp. 479-490
-
-
Cundliffe, E.1
-
6
-
-
0023748768
-
Mechanism of action of DuP 721: Inhibition of an early event during initiation of protein synthesis
-
Eustice, D.C., Feldman, P.A., Zahac, I., and Slee, A.M. (1988) Mechanism of action of DuP 721: inhibition of an early event during initiation of protein synthesis. Antimicrob Agents Chemother 32: 1218-1222.
-
(1988)
Antimicrob Agents Chemother
, vol.32
, pp. 1218-1222
-
-
Eustice, D.C.1
Feldman, P.A.2
Zahac, I.3
Slee, A.M.4
-
7
-
-
0035857967
-
Infections due to vancomycin-resistant Enterococcus faecium resistant to linezolid
-
Gonzales, R.D., Schreckensberger, P.C., Graham, M.B., Kelkar, S., DenBesten, K., and Quinn, J.P. (2001) Infections due to vancomycin-resistant Enterococcus faecium resistant to linezolid. Lancet 357: 1179.
-
(2001)
Lancet
, vol.357
, pp. 1179
-
-
Gonzales, R.D.1
Schreckensberger, P.C.2
Graham, M.B.3
Kelkar, S.4
DenBesten, K.5
Quinn, J.P.6
-
8
-
-
0027996396
-
The ribosomal RNA (rrn) operons of fast-growing mycobacteria: Primary and secondary structures and their relation to rrn operons of pathogenic slow-growers
-
Ji, Y., Colston, M.J., and Cox, R.A. (1994) The ribosomal RNA (rrn) operons of fast-growing mycobacteria: primary and secondary structures and their relation to rrn operons of pathogenic slow-growers. Microbiology 140: 2829-2840.
-
(1994)
Microbiology
, vol.140
, pp. 2829-2840
-
-
Ji, Y.1
Colston, M.J.2
Cox, R.A.3
-
9
-
-
0036177450
-
Linezolid-resistant Enterococcus faecium isolated from a patient without prior exposure to an oxazolidinone: Report from the SENTRY antimicrobial surveillance program
-
Jones, R.N., Della-Latta, P., Lee, L.V., and Biedenbach, D.J. (2002) Linezolid-resistant Enterococcus faecium isolated from a patient without prior exposure to an oxazolidinone: report from the SENTRY antimicrobial surveillance program. Diagn Micobiol Infect Dis 42: 137-139.
-
(2002)
Diagn Micobiol Infect Dis
, vol.42
, pp. 137-139
-
-
Jones, R.N.1
Della-Latta, P.2
Lee, L.V.3
Biedenbach, D.J.4
-
10
-
-
0033584879
-
Resistance mutations in 23S rRNA identify the site of action of protein synthesis inhibitor, linezolid, in the ribosomal peptidyl transferase center
-
Kloss, P., Xiong, L., Shinabarger, D., and Mankin, A.S. (1999) Resistance mutations in 23S rRNA identify the site of action of protein synthesis inhibitor, linezolid, in the ribosomal peptidyl transferase center. J Mol Biol 294: 93-101.
-
(1999)
J Mol Biol
, vol.294
, pp. 93-101
-
-
Kloss, P.1
Xiong, L.2
Shinabarger, D.3
Mankin, A.S.4
-
11
-
-
0030773903
-
The oxazolidinone eperezolid binds to the 50S ribosomal subunit and competes with binding of chloramphenicol and lincomycin
-
Lin, A.H., Murray, R.W., Vidmar, T.J., and Marotti, K.R. (1997) The oxazolidinone eperezolid binds to the 50S ribosomal subunit and competes with binding of chloramphenicol and lincomycin. Antimicrob Agents Chemother 41: 2127-2131.
-
(1997)
Antimicrob Agents Chemother
, vol.41
, pp. 2127-2131
-
-
Lin, A.H.1
Murray, R.W.2
Vidmar, T.J.3
Marotti, K.R.4
-
12
-
-
0013818420
-
The formation of N-formyl-methionyl-tRNA
-
Marcker, K.A. (1965) The formation of N-formyl-methionyl-tRNA. J Mol Biol 14: 63-70.
-
(1965)
J Mol Biol
, vol.14
, pp. 63-70
-
-
Marcker, K.A.1
-
13
-
-
0033032414
-
Ribosomal RNA is the target for oxazolidinones, a novel class of translational inhibitors
-
Matassova, N.B., Rodnina, M.V., Endermann, R., Kroll, H.-P., Pleiss, U., Wild, H., and Wintermeyer, W. (1999) Ribosomal RNA is the target for oxazolidinones, a novel class of translational inhibitors. RNA 5: 939-946.
-
(1999)
RNA
, vol.5
, pp. 939-946
-
-
Matassova, N.B.1
Rodnina, M.V.2
Endermann, R.3
Kroll, H.-P.4
Pleiss, U.5
Wild, H.6
Wintermeyer, W.7
-
14
-
-
0014219393
-
Ribosome-catalysed reaction of puromycin with a formyl-methionine-containing oligonucleotide
-
Monro, R.E., and Marcker, K.A. (1967) Ribosome-catalysed reaction of puromycin with a formyl-methionine-containing oligonucleotide. J Mol Biol 25: 347-350.
-
(1967)
J Mol Biol
, vol.25
, pp. 347-350
-
-
Monro, R.E.1
Marcker, K.A.2
-
15
-
-
0031956779
-
Ribosomes from an oxazolidinone-resistant mutant confer resistance to eperezolid in a Staphylococcus aureus cell-free transcription-translation assay
-
Murray, R.W., Schaadt, R.D., Zurenko, G.E., and Marotti, K.R. (1998) Ribosomes from an oxazolidinone-resistant mutant confer resistance to eperezolid in a Staphylococcus aureus cell-free transcription-translation assay. Antimicrob Agents Chemother 42: 947-950.
-
(1998)
Antimicrob Agents Chemother
, vol.42
, pp. 947-950
-
-
Murray, R.W.1
Schaadt, R.D.2
Zurenko, G.E.3
Marotti, K.R.4
-
16
-
-
0035029364
-
Biological cost and compensatory evolution in fusidJc acid-resistant Staphylococcus aureus
-
Nagaev, I., Bjorkman, J., Andersson, D.I., and Hughes, D. (2001) Biological cost and compensatory evolution in fusidJc acid-resistant Staphylococcus aureus. Mol Microbiol 40: 433-439.
-
(2001)
Mol Microbiol
, vol.40
, pp. 433-439
-
-
Nagaev, I.1
Bjorkman, J.2
Andersson, D.I.3
Hughes, D.4
-
17
-
-
0034637161
-
The structural basis of ribosome activity in peptide bond synthesis
-
Nissen, P., Hansen, J., Ban, N., Moore, P.B., and Steitz, T.A. (2000) The structural basis of ribosome activity in peptide bond synthesis. Science 289: 920-930.
-
(2000)
Science
, vol.289
, pp. 920-930
-
-
Nissen, P.1
Hansen, J.2
Ban, N.3
Moore, P.B.4
Steitz, T.A.5
-
18
-
-
0035001923
-
Linezolid - A review of the first oxazolidinone
-
Norrby, R. (2001) Linezolid - a review of the first oxazolidinone. Exp Opin Pharmacother 2: 293-302.
-
(2001)
Exp Opin Pharmacother
, vol.2
, pp. 293-302
-
-
Norrby, R.1
-
19
-
-
0035942753
-
Ribosomal peptidyl transferase can withstand mutations at the putative catalytic nucleotide
-
Polacek, N., Gaynor, M., Yassin, A., and Mankin, A.S. (2001) Ribosomal peptidyl transferase can withstand mutations at the putative catalytic nucleotide. Nature 411: 498-501.
-
(2001)
Nature
, vol.411
, pp. 498-501
-
-
Polacek, N.1
Gaynor, M.2
Yassin, A.3
Mankin, A.S.4
-
21
-
-
0034962929
-
Resistance to linezolid: Characterization of mutations in rRNA and comparison of their occurrences in vancomycin-resistant enterococci
-
Prystrowsky, J., Siddiqui, F., Chosay, J., Shinabarger, D.L., Millichap, J., Peterson, L.R., and Noskin, G.A. (2001) Resistance to linezolid: characterization of mutations in rRNA and comparison of their occurrences in vancomycin-resistant enterococci. Antimicrob Agents Chemother 45: 2154-2156.
-
(2001)
Antimicrob Agents Chemother
, vol.45
, pp. 2154-2156
-
-
Prystrowsky, J.1
Siddiqui, F.2
Chosay, J.3
Shinabarger, D.L.4
Millichap, J.5
Peterson, L.R.6
Noskin, G.A.7
-
22
-
-
0029800114
-
Introducing mutations into a chromosomal rRNA gene using a genetically modified eubacterial host with a single rRNA operon
-
Sander, P., Prammananan, T., and Böttger, E.C. (1996) Introducing mutations into a chromosomal rRNA gene using a genetically modified eubacterial host with a single rRNA operon. Mol Microbiol 22: 841-848.
-
(1996)
Mol Microbiol
, vol.22
, pp. 841-848
-
-
Sander, P.1
Prammananan, T.2
Böttger, E.C.3
-
23
-
-
0030669088
-
The role of ribosomal RNAs in macrolide resistance
-
Sander, P., Prammananan, T., Meier, A., Frischkorn. K., and Böttger, E.C. (1997) The role of ribosomal RNAs in macrolide resistance. Mol Microbiol 26: 469-480.
-
(1997)
Mol Microbiol
, vol.26
, pp. 469-480
-
-
Sander, P.1
Prammananan, T.2
Meier, A.3
Frischkorn, K.4
Böttger, E.C.5
-
24
-
-
0036237703
-
Fitness cost of chromosomal drug resistance conferring mutations
-
Sander, P., Springer, B., Prammananan, T., Sturmfels, A., Kappler, M., Pletschette, M., and Böttger, E.C. (2002) Fitness cost of chromosomal drug resistance conferring mutations. Antimicrob Agents Chemother 46: 1204-1211.
-
(2002)
Antimicrob Agents Chemother
, vol.46
, pp. 1204-1211
-
-
Sander, P.1
Springer, B.2
Prammananan, T.3
Sturmfels, A.4
Kappler, M.5
Pletschette, M.6
Böttger, E.C.7
-
25
-
-
0035950132
-
Structural basis for the interaction of antibiotics with the peptidyl transferase centre in eubacteria
-
Schluenzen, F., Zaivach, R., Harms, J., Bashan, A., Tocilj, A., Albrecht, R., et al. (2001) Structural basis for the interaction of antibiotics with the peptidyl transferase centre in eubacteria. Nature 413: 814-821.
-
(2001)
Nature
, vol.413
, pp. 814-821
-
-
Schluenzen, F.1
Zaivach, R.2
Harms, J.3
Bashan, A.4
Tocilj, A.5
Albrecht, R.6
-
26
-
-
0032846686
-
Mechanisms of action of the oxazolidinone antibacterial agents
-
Shinabarger, D.L. (1999) Mechanisms of action of the oxazolidinone antibacterial agents. Exp Opin Invest Drugs 8: 1195-1202.
-
(1999)
Exp Opin Invest Drugs
, vol.8
, pp. 1195-1202
-
-
Shinabarger, D.L.1
-
27
-
-
0030793842
-
Mechanism of action of oxazolidinones: Effects of linezolid and eperezolid on translation reactions
-
Shinabarger, D.L., Marotti, K.R., Murray, R.W., Lin, A.H., Melchior, E.P., Swaney, S.M., et al. (1997) Mechanism of action of oxazolidinones: effects of linezolid and eperezolid on translation reactions. Antimicrob Agents Chemother 41: 2132-2136.
-
(1997)
Antimicrob Agents Chemother
, vol.41
, pp. 2132-2136
-
-
Shinabarger, D.L.1
Marotti, K.R.2
Murray, R.W.3
Lin, A.H.4
Melchior, E.P.5
Swaney, S.M.6
-
28
-
-
0025081151
-
Isolation and characterization of efficient plasmid transformation mutants of Mycobacterium smegmatis
-
Snapper, S.B., Melton, R.E., Mustafa, S., Kieser, T., and Jacobs, W.R. (1990) Isolation and characterization of efficient plasmid transformation mutants of Mycobacterium smegmatis. Mol Microbiol 4: 1911-1919.
-
(1990)
Mol Microbiol
, vol.4
, pp. 1911-1919
-
-
Snapper, S.B.1
Melton, R.E.2
Mustafa, S.3
Kieser, T.4
Jacobs, W.R.5
-
29
-
-
0002477677
-
Isolation and analysis of ribosomes from prokaryotes eukaryotes, and organelles
-
Spedding, G. (ed.). Oxford: Oxford University Press
-
Spedding, G. (1990) Isolation and analysis of ribosomes from prokaryotes eukaryotes, and organelles. In Ribosomes and Protein Synthesis, a Practical Approach. Spedding, G. (ed.). Oxford: Oxford University Press, pp. 1-29.
-
(1990)
Ribosomes and Protein Synthesis, a Practical Approach
, pp. 1-29
-
-
Spedding, G.1
-
30
-
-
0031729229
-
The oxazolidinone linezolid inhibits initiation of protein synthesis in bacteria
-
Swaney, S.M., Aoki, H., Ganoza, M.C., and Shinabarger, D.L. (1998) The oxazolidinone linezolid inhibits initiation of protein synthesis in bacteria. Antimicrob Agents Chemother 42: 3251-3255.
-
(1998)
Antimicrob Agents Chemother
, vol.42
, pp. 3251-3255
-
-
Swaney, S.M.1
Aoki, H.2
Ganoza, M.C.3
Shinabarger, D.L.4
-
31
-
-
0035979232
-
Analysis of mutations at residue A2451 and G2447 of 23S rRNA in the peptidyltransferase active site of the 50S ribosomal subunit
-
Thompson, J., Kim, D.F., O'Connor, M., Lieberman, K.R., Bayfield, M.A., Gregory, S.T., et al. (2001) Analysis of mutations at residue A2451 and G2447 of 23S rRNA in the peptidyltransferase active site of the 50S ribosomal subunit. Proc Natl Acad Sci USA 98: 9002-9007.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 9002-9007
-
-
Thompson, J.1
Kim, D.F.2
O'Connor, M.3
Lieberman, K.R.4
Bayfield, M.A.5
Gregory, S.T.6
-
32
-
-
0035928419
-
Linezolid resistance in a clinical isolate of Staphylococcus aureus
-
Tsiodras, S., Gold, H.S., Sakoulas, G., Eliopoulos, G.M., Winnersten, C., Venkataraman, L., and Moellering, R.C. (2001) Linezolid resistance in a clinical isolate of Staphylococcus aureus. Lancet 358: 207-208.
-
(2001)
Lancet
, vol.358
, pp. 207-208
-
-
Tsiodras, S.1
Gold, H.S.2
Sakoulas, G.3
Eliopoulos, G.M.4
Winnersten, C.5
Venkataraman, L.6
Moellering, R.C.7
-
33
-
-
0033797686
-
Oxazolidinone resistance mutations in 23S rRNA of Escherichia coli reveal the central region of domain V as the primary site of drug action
-
Xiong, L., Kloss, P., Douthwaite, S., Andersen, N.M., Swaney, S., Shinabarger, D.L., and Mankin, A.S. (2000) Oxazolidinone resistance mutations in 23S rRNA of Escherichia coli reveal the central region of domain V as the primary site of drug action. J Bacteriol 182: 5325-5331.
-
(2000)
J Bacteriol
, vol.182
, pp. 5325-5331
-
-
Xiong, L.1
Kloss, P.2
Douthwaite, S.3
Andersen, N.M.4
Swaney, S.5
Shinabarger, D.L.6
Mankin, A.S.7
-
34
-
-
0034768574
-
pKa of adenine 2451 in the ribosomal peptidyl transferase center remains elusive
-
Xiong, L., Polacek, N., Sander, P., Böttger. E.C., and Mankin, A. (2001) pKa of adenine 2451 in the ribosomal peptidyl transferase center remains elusive. RNA 7: 1365-1369.
-
(2001)
RNA
, vol.7
, pp. 1365-1369
-
-
Xiong, L.1
Polacek, N.2
Sander, P.3
Böttger, E.C.4
Mankin, A.5
-
35
-
-
0029942573
-
In vitro activities of U-100592 and U-100766, novel oxazolidinone antibacterial agents
-
Zurenko, G.E., Yagi, B.H., Schaadt, R.D., Allison, J.W., Kilburn, J.O., Glickman, S.E. et al. (1996) In vitro activities of U-100592 and U-100766, novel oxazolidinone antibacterial agents. Antimicrob Agents Chemother 40: 839-845.
-
(1996)
Antimicrob Agents Chemother
, vol.40
, pp. 839-845
-
-
Zurenko, G.E.1
Yagi, B.H.2
Schaadt, R.D.3
Allison, J.W.4
Kilburn, J.O.5
Glickman, S.E.6
-
36
-
-
0035491151
-
Oxazolidinones: A new class of antibacterials
-
Zurenko, G.E., Gibson, J.K., Shinabarger, D.L., Aristoff, P.A., Ford, C.W., and Tarpley, W.G. (2001) Oxazolidinones: a new class of antibacterials. Curr Opin Pharmacol 1: 470-476.
-
(2001)
Curr Opin Pharmacol
, vol.1
, pp. 470-476
-
-
Zurenko, G.E.1
Gibson, J.K.2
Shinabarger, D.L.3
Aristoff, P.A.4
Ford, C.W.5
Tarpley, W.G.6
|