The protein synthesis inhibitors, oxazolidinones and chloramphenicol, cause extensive translational inaccuracy in vivo

Journal of Molecular Biology

Volumn 322, Issue 2, 2002, Pages 273-279

  Thompson, Jill ^a   O'Connor, Michael ^a   Mills, Jonathan A ^b   Dahlberg, Albert E ^a  

^a BROWN UNIVERSITY   (United States)

^b Essential Therapeutics Inc   (United States)

Author keywords

Antibiotics; Frameshifting; Nonsense suppression; Ribosomes; Translational fidelity

Indexed keywords

AMINO ACID DERIVATIVE; AMINOGLYCOSIDE ANTIBIOTIC AGENT; CHLORAMPHENICOL; ENZYME INHIBITOR; GENTAMICIN; LINEZOLID; OXAZOLIDINONE DERIVATIVE; PAROMOMYCIN; PEPTIDYLTRANSFERASE; UNCLASSIFIED DRUG; XA 043;

ARTICLE; CONTROLLED STUDY; DRUG MECHANISM; DRUG PROTEIN BINDING; IN VIVO STUDY; NONHUMAN; PRIORITY JOURNAL; REPORTER GENE; RIBOSOMAL FRAMESHIFTING; RIBOSOME SUBUNIT; STOP CODON;

BACTERIA (MICROORGANISMS);

EID: 0036384314     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-2836(02)00784-2     Document Type: Article

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