A novel site of antibiotic action in the ribosome: Interaction of evernimicin with the large ribosomal subunit

Proceedings of the National Academy of Sciences of the United States of America

Volumn 98, Issue 7, 2001, Pages 3726-3731

  Belova, Larissa ^a   Tenson, Tanel ^b   Xiong, Liqun ^a   McNicholas, Paul M ^c   Mankin, Alexander S ^a  

^a UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

^b UNIVERSITY OF TARTU   (Estonia)

^c MERCK RESEARCH LABORATORIES   (United States)

Author keywords

Antibiotics; Drug resistance; L16; Ribosomal protein; rRNA

Indexed keywords

ANTIBIOTIC AGENT; BACTERIAL PROTEIN; EVERNIMICIN; INITIATION FACTOR 2; OLIGOSACCHARIDE; RIBOSOME RNA; RNA 23S;

ARTICLE; DRUG BINDING SITE; DRUG MECHANISM; GENE MUTATION; HALOBACTERIUM SALINARUM; MINIMUM INHIBITORY CONCENTRATION; PRIORITY JOURNAL; RIBOSOME SUBUNIT; RNA GENE; RNA PROBE;

AMINOGLYCOSIDES; ANTI-BACTERIAL AGENTS; BINDING SITES; DRUG RESISTANCE, MICROBIAL; HALOBACTERIUM SALINARUM; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; NUCLEIC ACID CONFORMATION; RNA, ARCHAEAL; RNA, BACTERIAL; RNA, RIBOSOMAL, 23S;

ARCHAEA; BACTERIA (MICROORGANISMS); HALOBACTERIUM SALINARUM;

EID: 0035957387     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.071527498     Document Type: Article

References (50)