Cross-linking in the living cell locates the site of action of oxazolidinone antibiotics

Journal of Biological Chemistry

Volumn 278, Issue 24, 2003, Pages 21972-21979

  Colca, Jerry R ^a   McDonald, William G ^a   Waldon, Daniel J ^a   Thomasco, Lisa M ^a   Gadwood, Robert C ^a   Lund, Eric T ^a   Cavey, Gregory S ^a   Mathews, W Rodney ^a   Adams, Lonnie D ^a   Cecil, Eric T ^a   Pearson, James D ^a   Bock, Jeffrey H ^a   Mott, John E ^a   Shinabarger, Dean L ^a   Xiong, Liqun ^b   Mankin, Alexander S ^b  

^a PFIZER INC   (United States)

^b UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; CROSSLINKING; POLYPEPTIDES; PROTEINS; SYNTHESIS (CHEMICAL);

PROTEIN SYNTHESIS;

ANTIBIOTICS;

ANTIINFECTIVE AGENT; EPEREZOLID; LINEZOLID; OXAZOLIDINONE DERIVATIVE; PNU 107112; PNU 259621; RIBOSOME RNA; TRANSFER RNA; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CROSS LINKING; DRUG MECHANISM; DRUG PROTEIN BINDING; DRUG STRUCTURE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN SYNTHESIS INHIBITION; SEQUENCE HOMOLOGY; STAPHYLOCOCCUS AUREUS;

AMINO ACID SEQUENCE; ANTI-BACTERIAL AGENTS; BINDING SITES; CROSS-LINKING REAGENTS; ELECTROPHORESIS, POLYACRYLAMIDE GEL; MODELS, CHEMICAL; MODELS, GENETIC; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; NUCLEIC ACID CONFORMATION; OXAZOLIDINONES; PEPTIDES; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; PROTEIN SYNTHESIS INHIBITORS; RNA; RNA, RIBOSOMAL, 23S; RNA, TRANSFER; STAPHYLOCOCCUS AUREUS; TRANSCRIPTION FACTORS;

ANIMALIA; STAPHYLOCOCCUS; STAPHYLOCOCCUS AUREUS;

EID: 0037821645     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M302109200     Document Type: Article

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