Structural basis for the interaction of antibiotics with the peptidyl transferase centre in eubacteria

Nature

Volumn 413, Issue 6858, 2001, Pages 814-821

  Schlünzen, Frank ^a   Zarivach, Raz ^b   Harms, Jörg ^a   Bashan, Anat ^b   Tocilj, Ante ^a,c   Albrecht, Renate ^c   Yonath, Ada ^a,b   Franceschi, François ^c  

^a MAX PLANCK UNIT FOR STRUCTURAL MOLECULAR BIOLOGY   (Germany)

^b WEIZMANN INSTITUTE OF SCIENCE   (Israel)

^c MAX PLANCK INSTITUTE FOR MOLECULAR GENETICS   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTICS; DRUG THERAPY; PROTEINS; RNA; STRUCTURAL ANALYSIS; X RAY ANALYSIS;

PEPTIDYL TRANSFERASE;

NATURAL SCIENCES;

ANTIBIOTIC AGENT; CHLORAMPHENICOL; CLINDAMYCIN; ERYTHROMYCIN; MAGNESIUM ION; PEPTIDYLTRANSFERASE; ROXITHROMYCIN;

ANTIBIOTICS; BIOCHEMISTRY; PROTEIN; RNA;

ARTICLE; BINDING SITE; DEINOCOCCUS RADIODURANS; DRUG DESIGN; DRUG PROTEIN BINDING; DRUG TARGETING; EUBACTERIUM; NONHUMAN; PRIORITY JOURNAL; PROTEIN SYNTHESIS; RIBOSOME;

ANTI-BACTERIAL AGENTS; BACTERIA; BASE SEQUENCE; BINDING SITES; CHLORAMPHENICOL; CRYSTALLOGRAPHY, X-RAY; MACROLIDES; MAGNESIUM; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PEPTIDYL TRANSFERASES; PROTEIN CONFORMATION; RIBOSOMAL PROTEINS; RIBOSOMES; RNA, BACTERIAL; RNA, RIBOSOMAL, 23S; STRUCTURE-ACTIVITY RELATIONSHIP;

BACTERIA (MICROORGANISMS); DEINOCOCCUS RADIODURANS;

EID: 0035950132     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/35101544     Document Type: Article

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