-
1
-
-
0034088491
-
Identification and analysis of bacterial protein secretion inhibitors utilizing a SecA-LacZ reporter fusion system
-
Alksne, L.E., Burgio, P., Hu, W., Feld, B., Singh, M.P., Tuckman, M., Petersen, P.J., Labthavikul, P., McGlynn, M., Barbieri, L., et al. 2000. Identification and analysis of bacterial protein secretion inhibitors utilizing a SecA-LacZ reporter fusion system. Antimicrob. Agents Chemother. 44: 1418-1427.
-
(2000)
Antimicrob. Agents Chemother.
, vol.44
, pp. 1418-1427
-
-
Alksne, L.E.1
Burgio, P.2
Hu, W.3
Feld, B.4
Singh, M.P.5
Tuckman, M.6
Petersen, P.J.7
Labthavikul, P.8
McGlynn, M.9
Barbieri, L.10
-
2
-
-
0025786601
-
Construction of cloning vectors for Bacillus thuringiensis
-
Arantes, O. and Lereclus, D. 1991. Construction of cloning vectors for Bacillus thuringiensis. Gene 108: 115-119.
-
(1991)
Gene
, vol.108
, pp. 115-119
-
-
Arantes, O.1
Lereclus, D.2
-
3
-
-
0032702687
-
Stress responses as a tool to detect and characterize the mode of action of antibacterial agents
-
Bianchi, A.A. and Baneyx, F. 1999. Stress responses as a tool to detect and characterize the mode of action of antibacterial agents. Appl. Environ. Microbiol. 65: 5023-5027.
-
(1999)
Appl. Environ. Microbiol.
, vol.65
, pp. 5023-5027
-
-
Bianchi, A.A.1
Baneyx, F.2
-
4
-
-
0033257746
-
The new antibiotics
-
Breithaupt, H. 1999. The new antibiotics. Nat. Biotechnol. 17: 1165-1169.
-
(1999)
Nat. Biotechnol.
, vol.17
, pp. 1165-1169
-
-
Breithaupt, H.1
-
5
-
-
0034780806
-
Bacterial fatty acid biosynthesis: Targets for antibacterial drug discovery
-
Campbell, J.W. and Cronan Jr., J.E. 2001. Bacterial fatty acid biosynthesis: Targets for antibacterial drug discovery. Annu. Rev. Microbiol. 55: 305-332.
-
(2001)
Annu. Rev. Microbiol.
, vol.55
, pp. 305-332
-
-
Campbell, J.W.1
Cronan Jr., J.E.2
-
6
-
-
0033986294
-
β-Ketoacyl-acyl carrier protein synthase III (FabH) is a determining factor in branched-chain fatty acid biosynthesis
-
Choi, K.H., Heath, R.J., and Rock, C.O. 2000. β-Ketoacyl-acyl carrier protein synthase III (FabH) is a determining factor in branched-chain fatty acid biosynthesis. J. Bacteriol. 182: 365-370.
-
(2000)
J. Bacteriol.
, vol.182
, pp. 365-370
-
-
Choi, K.H.1
Heath, R.J.2
Rock, C.O.3
-
7
-
-
0036090890
-
Exploiting current understanding of antibiotic action for discovery of new drugs
-
Chopra, I., Hesse, L., and O'Neill, A.J. 2002. Exploiting current understanding of antibiotic action for discovery of new drugs. J. Appl. Microbiol. 92 Suppl: 4S-15S.
-
(2002)
J. Appl. Microbiol.
, vol.92
, Issue.SUPPL.
-
-
Chopra, I.1
Hesse, L.2
O'Neill, A.J.3
-
8
-
-
0036256037
-
An array of target-specific screening strains for antibacterial discovery
-
DeVito, J.A., Mills, J.A., Liu, V.G., Agarwal, A., Sizemore, C.F., Yao, Z., Stoughton, D.M., Cappiello, M.G., Barbosa, M.D., Foster, L.A., et al. 2002. An array of target-specific screening strains for antibacterial discovery. Nat. Biotechnol. 20: 478-483.
-
(2002)
Nat. Biotechnol.
, vol.20
, pp. 478-483
-
-
DeVito, J.A.1
Mills, J.A.2
Liu, V.G.3
Agarwal, A.4
Sizemore, C.F.5
Yao, Z.6
Stoughton, D.M.7
Cappiello, M.G.8
Barbosa, M.D.9
Foster, L.A.10
-
9
-
-
0035889664
-
The impact of expression profiling technologies on antimicrobial target identification and validation
-
Fischer, H.P. 2001. The impact of expression profiling technologies on antimicrobial target identification and validation. Drug Discov. Today 6: 1149-1150.
-
(2001)
Drug Discov. Today
, vol.6
, pp. 1149-1150
-
-
Fischer, H.P.1
-
10
-
-
0036271625
-
A genome-wide strategy for the identification of essential genes in Staphylococcus aureus
-
Forsyth, R.A., Haselbeck, R.J., Ohlsen, K.L., Yamamoto, R.T., Xu, H., Trawick, J.D., Wall, D., Wang, L., Brown-Driver, V., Froelich, J.M., et al. 2002. A genome-wide strategy for the identification of essential genes in Staphylococcus aureus. Mol. Microbiol. 43: 1387-1400.
-
(2002)
Mol. Microbiol.
, vol.43
, pp. 1387-1400
-
-
Forsyth, R.A.1
Haselbeck, R.J.2
Ohlsen, K.L.3
Yamamoto, R.T.4
Xu, H.5
Trawick, J.D.6
Wall, D.7
Wang, L.8
Brown-Driver, V.9
Froelich, J.M.10
-
11
-
-
0011962697
-
Genome-wide mRNA profiling: Impact on compound evaluation and target identification in anti-bacterial research
-
Freiberg, C. and Brunner, N.A. 2002. Genome-wide mRNA profiling: Impact on compound evaluation and target identification in anti-bacterial research. Targets 1: 20-29.
-
(2002)
Targets
, vol.1
, pp. 20-29
-
-
Freiberg, C.1
Brunner, N.A.2
-
12
-
-
0036334571
-
From genetic footprinting to antimicrobial drug targets: Examples in cofactor biosynthetic pathways
-
Gerdes, S.Y., Scholle, M.D., D'Souza, M., Bernal, A., Baev, M.V., Farrell, M., Kurnasov, O.V., Daugherty, M.D., Mseeh, F., Polanuyer, B.M., et al. 2002. From genetic footprinting to antimicrobial drug targets: Examples in cofactor biosynthetic pathways. J. Bacteriol. 184: 4555-4572.
-
(2002)
J. Bacteriol.
, vol.184
, pp. 4555-4572
-
-
Gerdes, S.Y.1
Scholle, M.D.2
D'Souza, M.3
Bernal, A.4
Baev, M.V.5
Farrell, M.6
Kurnasov, O.V.7
Daugherty, M.D.8
Mseeh, F.9
Polanuyer, B.M.10
-
13
-
-
0035154372
-
Gene expression changes triggered by exposure of Haemophilus influenzae to novobiocin or ciprofloxacin: Combined transcription and translation analysis
-
Gmuender, H., Kuratli, K., Di Padova, K., Gray, C.P., Keck, W., and Evers, S. 2001. Gene expression changes triggered by exposure of Haemophilus influenzae to novobiocin or ciprofloxacin: Combined transcription and translation analysis. Genome Res. 11: 28-42.
-
(2001)
Genome Res.
, vol.11
, pp. 28-42
-
-
Gmuender, H.1
Kuratli, K.2
Di Padova, K.3
Gray, C.P.4
Keck, W.5
Evers, S.6
-
14
-
-
0031736387
-
Multimodular penicillin-binding proteins: An enigmatic family of orthologs and paralogs
-
Goffin, C. and Ghuysen, J.M. 1998. Multimodular penicillin-binding proteins: An enigmatic family of orthologs and paralogs. Microbiol. Mol. Biol. Rev. 62: 1079-1093.
-
(1998)
Microbiol. Mol. Biol. Rev.
, vol.62
, pp. 1079-1093
-
-
Goffin, C.1
Ghuysen, J.M.2
-
15
-
-
0034786939
-
Unfolding of microarray data
-
Goryachev, A.B., Macgregor, P.F., and Edwards, A.M. 2001. Unfolding of microarray data. J. Comput. Biol. 8: 443-461.
-
(2001)
J. Comput. Biol.
, vol.8
, pp. 443-461
-
-
Goryachev, A.B.1
Macgregor, P.F.2
Edwards, A.M.3
-
16
-
-
0032695731
-
Bacterial targets and antibiotics: Genome-based drug discovery
-
Gray, C.P. and Keck, W. 1999. Bacterial targets and antibiotics: Genome-based drug discovery. Cell Mol. Life Sci. 56: 779-787.
-
(1999)
Cell Mol. Life Sci.
, vol.56
, pp. 779-787
-
-
Gray, C.P.1
Keck, W.2
-
17
-
-
0032515066
-
Broad spectrum antimicrobial biocides target the FabI component of fatty acid synthesis
-
Heath, R.J., Yu, Y.T., Shapiro, M.A., Olson, E., and Rock, C.O. 1998. Broad spectrum antimicrobial biocides target the FabI component of fatty acid synthesis. J. Biol. Chem. 273: 30316-30320.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 30316-30320
-
-
Heath, R.J.1
Yu, Y.T.2
Shapiro, M.A.3
Olson, E.4
Rock, C.O.5
-
18
-
-
0034804919
-
Lipid biosynthesis as a target for antibacterial agents
-
Heath, R.J., White, S.W., and Rock, C.O. 2001. Lipid biosynthesis as a target for antibacterial agents. Prog. Lipid Res. 40: 467-497.
-
(2001)
Prog. Lipid Res.
, vol.40
, pp. 467-497
-
-
Heath, R.J.1
White, S.W.2
Rock, C.O.3
-
19
-
-
0036468362
-
Prokaryotic transcription regulators: More than just the helix-turn-helix motif
-
Huffman, J.L. and Brennan, R.G. 2002. Prokaryotic transcription regulators: More than just the helix-turn-helix motif. Curr. Opin. Struct. Biol. 12: 98-106.
-
(2002)
Curr. Opin. Struct. Biol.
, vol.12
, pp. 98-106
-
-
Huffman, J.L.1
Brennan, R.G.2
-
20
-
-
0035929121
-
Identification of critical staphylococcal genes using conditional phenotypes generated by antisense RNA
-
Ji, Y., Zhang, B., Van Horn, S.F., Warren, P., Woodnutt, G., Burnham, M.K., and Rosenberg, M. 2001. Identification of critical staphylococcal genes using conditional phenotypes generated by antisense RNA. Science 293: 2266-2269.
-
(2001)
Science
, vol.293
, pp. 2266-2269
-
-
Ji, Y.1
Zhang, B.2
Van Horn, S.F.3
Warren, P.4
Woodnutt, G.5
Burnham, M.K.6
Rosenberg, M.7
-
21
-
-
0024146365
-
β-Ketoacyl-ACP synthase I of Escherichia coli: Nucleotide sequence of the fabB gene and identification of the cerulenin binding residue
-
Kauppinen, S., Siggaard-Andersen, M., and von Wettstein-Knowles, P. 1988. β-Ketoacyl-ACP synthase I of Escherichia coli: Nucleotide sequence of the fabB gene and identification of the cerulenin binding residue. Carlsbery Res. Commun. 53: 357-370.
-
(1988)
Carlsbery Res. Commun.
, vol.53
, pp. 357-370
-
-
Kauppinen, S.1
Siggaard-Andersen, M.2
von Wettstein-Knowles, P.3
-
22
-
-
0030731108
-
The complete genome sequence of the gram-positive bacterium Bacillus subtilis
-
Kunst, F., Ogasawara, N., Moszer, I., Albertini, A.M., Alloni, G., Azevedo, V., Bertero, M.G., Bessieres, P., Bolotin, A., Borchert, S., et al. 1997. The complete genome sequence of the gram-positive bacterium Bacillus subtilis. Nature 390: 249-256.
-
(1997)
Nature
, vol.390
, pp. 249-256
-
-
Kunst, F.1
Ogasawara, N.2
Moszer, I.3
Albertini, A.M.4
Alloni, G.5
Azevedo, V.6
Bertero, M.G.7
Bessieres, P.8
Bolotin, A.9
Borchert, S.10
-
23
-
-
0027912333
-
Detecting subtle sequence signals: A Gibbs sampling strategy for multiple alignment
-
Lawrence, C.E., Altschul, S.F., Boguski, M.S., Liu, J.S., Neuwald, A.F., and Wootton, J.C. 1993. Detecting subtle sequence signals: A Gibbs sampling strategy for multiple alignment. Science 262: 208-214.
-
(1993)
Science
, vol.262
, pp. 208-214
-
-
Lawrence, C.E.1
Altschul, S.F.2
Boguski, M.S.3
Liu, J.S.4
Neuwald, A.F.5
Wootton, J.C.6
-
24
-
-
0035253676
-
Phylogenetic footprinting of transcription factor binding sites in proteobacterial genomes
-
McCue, L., Thompson, W., Carmack, C., Ryan, M.P., Liu, J.S., Derbyshire, V., and Lawrence, C.E. 2001. Phylogenetic footprinting of transcription factor binding sites in proteobacterial genomes. Nucleic Acids Res. 29: 774-782.
-
(2001)
Nucleic Acids Res.
, vol.29
, pp. 774-782
-
-
McCue, L.1
Thompson, W.2
Carmack, C.3
Ryan, M.P.4
Liu, J.S.5
Derbyshire, V.6
Lawrence, C.E.7
-
25
-
-
0036090929
-
Novel targets for the future development of antibacterial agents
-
McDevitt, D., Payne, D.J., Holmes, D.J., and Rosenberg, M. 2002. Novel targets for the future development of antibacterial agents. J. Appl. Microbiol. 92 Suppl: 28S-34S.
-
(2002)
J. Appl. Microbiol.
, vol.92
, Issue.SUPPL.
-
-
McDevitt, D.1
Payne, D.J.2
Holmes, D.J.3
Rosenberg, M.4
-
26
-
-
0033918228
-
Conservation of DNA regulatory motifs and discovery of new motifs in microbial genomes
-
McGuire, A.M., Hughes, J.D., and Church, G.M. 2000. Conservation of DNA regulatory motifs and discovery of new motifs in microbial genomes. Genome Res. 10: 744-757.
-
(2000)
Genome Res.
, vol.10
, pp. 744-757
-
-
McGuire, A.M.1
Hughes, J.D.2
Church, G.M.3
-
27
-
-
0033565546
-
Computer analysis of transcription regulatory patterns in completely sequenced bacterial genomes
-
Mironov, A.A., Koonin, E.V., Roytberg, M.A., and Gelfand, M.S. 1999. Computer analysis of transcription regulatory patterns in completely sequenced bacterial genomes. Nucleic Acids Res. 27: 2981-2989.
-
(1999)
Nucleic Acids Res.
, vol.27
, pp. 2981-2989
-
-
Mironov, A.A.1
Koonin, E.V.2
Roytberg, M.A.3
Gelfand, M.S.4
-
28
-
-
0033525885
-
Structure of the complex between the antibiotic cerulenin and its target, β-ketoacyl-acyl carrier protein synthase
-
Moche, M., Schneider, G., Edwards, P., Dehesh, K., and Lindqvist, Y. 1999. Structure of the complex between the antibiotic cerulenin and its target, β-ketoacyl-acyl carrier protein synthase. J. Biol. Chem. 274: 6031-6034.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 6031-6034
-
-
Moche, M.1
Schneider, G.2
Edwards, P.3
Dehesh, K.4
Lindqvist, Y.5
-
29
-
-
0035338328
-
Bacterial fatty-acid biosynthesis: A genomics-driven target for antibacterial drug discovery
-
Payne, D.J., Warren, P.V., Holmes, D.J., Ji, Y., and Lonsdale, J.T. 2001. Bacterial fatty-acid biosynthesis: A genomics-driven target for antibacterial drug discovery. Drug Discov. Today 6: 537-544.
-
(2001)
Drug Discov. Today
, vol.6
, pp. 537-544
-
-
Payne, D.J.1
Warren, P.V.2
Holmes, D.J.3
Ji, Y.4
Lonsdale, J.T.5
-
30
-
-
0036783668
-
Discovery of a novel and potent class of FabI-directed antibacterial agents
-
Payne, D.J., Miller, W.H., Berry, V., Brosky, J., Burgess, W.J., Chen, E., DeWolf Jr., W.E., Fosberry, A.P., Greenwood, R., Head, M.S., et al. 2002. Discovery of a novel and potent class of FabI-directed antibacterial agents. Antimicrob. Agents Chemother. 46: 3118-3124.
-
(2002)
Antimicrob. Agents Chemother.
, vol.46
, pp. 3118-3124
-
-
Payne, D.J.1
Miller, W.H.2
Berry, V.3
Brosky, J.4
Burgess, W.J.5
Chen, E.6
DeWolf Jr., W.E.7
Fosberry, A.P.8
Greenwood, R.9
Head, M.S.10
-
31
-
-
0036152265
-
Structure, conformation, and mechanism in the membrane transport of alkali metal ions by ionophoric antibiotics
-
Riddell, F.G. 2002. Structure, conformation, and mechanism in the membrane transport of alkali metal ions by ionophoric antibiotics. Chirality 14: 121-125.
-
(2002)
Chirality
, vol.14
, pp. 121-125
-
-
Riddell, F.G.1
-
32
-
-
0034678055
-
Harnessing the power of the genome in the search for new antibiotics
-
Rosamond, J. and Allsop, A. 2000. Harnessing the power of the genome in the search for new antibiotics. Science 287: 1973-1976.
-
(2000)
Science
, vol.287
, pp. 1973-1976
-
-
Rosamond, J.1
Allsop, A.2
-
33
-
-
0036640105
-
Co-expression pattern from DNA microarray experiments as a tool for operon prediction
-
Sabatti, C., Rohlin, L., Oh, M.K., and Liao, J.C. 2002. Co-expression pattern from DNA microarray experiments as a tool for operon prediction. Nucleic Acids Res. 30: 2886-2893.
-
(2002)
Nucleic Acids Res.
, vol.30
, pp. 2886-2893
-
-
Sabatti, C.1
Rohlin, L.2
Oh, M.K.3
Liao, J.C.4
-
34
-
-
0035026139
-
Response of Bacillus subtilis to cerulenin and acquisition of resistance
-
Schujman, G.E., Choi, K.H., Altabe, S., Rock, C.O., and de Mendoza, D. 2001. Response of Bacillus subtilis to cerulenin and acquisition of resistance. J. Bacteriol. 183: 3032-3040.
-
(2001)
J. Bacteriol.
, vol.183
, pp. 3032-3040
-
-
Schujman, G.E.1
Choi, K.H.2
Altabe, S.3
Rock, C.O.4
de Mendoza, D.5
-
35
-
-
0032752132
-
Interaction of cationic peptides with lipoteichoic acid and gram-positive bacteria
-
Scott, M.G., Gold, M.R., and Hancock, R.E. 1999. Interaction of cationic peptides with lipoteichoic acid and gram-positive bacteria. Infect. Immun. 67: 6445-6453.
-
(1999)
Infect. Immun.
, vol.67
, pp. 6445-6453
-
-
Scott, M.G.1
Gold, M.R.2
Hancock, R.E.3
-
36
-
-
0037315564
-
Global RNA half-life analysis in Escherichia coli reveals positional patterns of transcript degradation
-
Selinger, D.W., Saxena, R.M., Cheung, K.J., Church, G.M., and Rosenow, C. 2003. Global RNA half-life analysis in Escherichia coli reveals positional patterns of transcript degradation. Genome Res. 13: 216-223.
-
(2003)
Genome Res.
, vol.13
, pp. 216-223
-
-
Selinger, D.W.1
Saxena, R.M.2
Cheung, K.J.3
Church, G.M.4
Rosenow, C.5
-
37
-
-
0035991865
-
Stress-based identification and classification of antibacterial agents: Second-generation Escherichia coli reporter strains and optimization of detection
-
Shapiro, E. and Baneyx, F. 2002. Stress-based identification and classification of antibacterial agents: Second-generation Escherichia coli reporter strains and optimization of detection. Antimicrob. Agents Chemother. 46: 2490-2497.
-
(2002)
Antimicrob. Agents Chemother.
, vol.46
, pp. 2490-2497
-
-
Shapiro, E.1
Baneyx, F.2
-
38
-
-
0027524789
-
Temporal activation of β-glucanase synthesis in Bacillus subtilis is mediated by the GTP pool
-
Stulke,J ., Hanschke, R., and Hecker, M. 1993. Temporal activation of β-glucanase synthesis in Bacillus subtilis is mediated by the GTP pool. J. Gen. Microbiol. 139 (Pt 9): 2041-2045.
-
(1993)
J. Gen. Microbiol.
, vol.139
, Issue.PART 9
, pp. 2041-2045
-
-
Stulke, J.1
Hanschke, R.2
Hecker, M.3
-
39
-
-
0036215241
-
A pathway-specific cell based screening system to detect bacterial cell wall inhibitors
-
Sun, D., Cohen, S., Mani, N., Murphy, C., and Rothstein, D.M. 2002. A pathway-specific cell based screening system to detect bacterial cell wall inhibitors. J. Antibiot. (Tokyo) 55: 279-287.
-
(2002)
J. Antibiot. (Tokyo)
, vol.55
, pp. 279-287
-
-
Sun, D.1
Cohen, S.2
Mani, N.3
Murphy, C.4
Rothstein, D.M.5
-
40
-
-
0035950145
-
Gene expression in Pseudomonas aeruginosa biofilms
-
Whiteley, M., Bangera, M.G., Bumgarner, R.E., Parsek, M.R., Teitzel, G.M., Lory, S., and Greenberg, E.P. 2001. Gene expression in Pseudomonas aeruginosa biofilms. Nature 413: 860-864.
-
(2001)
Nature
, vol.413
, pp. 860-864
-
-
Whiteley, M.1
Bangera, M.G.2
Bumgarner, R.E.3
Parsek, M.R.4
Teitzel, G.M.5
Lory, S.6
Greenberg, E.P.7
-
41
-
-
0033607188
-
Exploring drug-induced alterations in gene expression in Mycobacterium tuberculosis by microarray hybridisation
-
Wilson, M., DeRisi, J., Kristensen, H.H., Imboden, P., Rane, S., Brown, P.O., and Schoolnik, G.K. 1999. Exploring drug-induced alterations in gene expression in Mycobacterium tuberculosis by microarray hybridisation. Proc. Natl. Acad. Sci. 96: 12833-12838.
-
(1999)
Proc. Natl. Acad. Sci.
, vol.96
, pp. 12833-12838
-
-
Wilson, M.1
DeRisi, J.2
Kristensen, H.H.3
Imboden, P.4
Rane, S.5
Brown, P.O.6
Schoolnik, G.K.7
|