Binding site of macrolide antibiotics on the ribosome: New resistance mutation identifies a specific interaction of ketolides with rRNA

Journal of Bacteriology

Volumn 183, Issue 23, 2001, Pages 6898-6907

  Garza Ramos, G ^a   Xiong, L ^a   Zhong, P ^a   Mankin, A ^a  

^a UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

A 192803; AZITHROMYCIN; CETHROMYCIN; ERYTHROMYCIN; KETOLIDE; MACROLIDE; RU 69874; TELITHROMYCIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIMICROBIAL ACTIVITY; ARTICLE; BINDING AFFINITY; BINDING SITE; CELL MUTANT; CONTROLLED STUDY; CRYSTAL STRUCTURE; DRUG BINDING; DRUG POTENCY; DRUG RESISTANCE; DRUG SENSITIVITY; ESCHERICHIA COLI; GENE ISOLATION; INHIBITION KINETICS; NONHUMAN; PRIORITY JOURNAL; RIBOSOME; STRUCTURE ANALYSIS;

ANTI-BACTERIAL AGENTS; BASE SEQUENCE; BINDING SITES; DRUG RESISTANCE, BACTERIAL; MACROLIDES; MOLECULAR SEQUENCE DATA; MUTATION; RIBOSOMES; RNA, RIBOSOMAL;

ANIMALIA; ESCHERICHIA COLI; NEGIBACTERIA;

EID: 0035162904     PISSN: 00219193     EISSN: None     Source Type: Journal    
DOI: 10.1128/JB.183.23.6898-6907.2001     Document Type: Article

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