Species-specific antibiotic-ribosome interactions: Implications for drug development

Biological Chemistry

Volumn 386, Issue 12, 2005, Pages 1239-1252

  Wilson, Daniel N ^a   Harms, Jörg M ^a   Nierhaus, Knud H ^a   Schlünzen, Frank ^a   Fucini, Paola ^a  

^a MAX PLANCK INSTITUTE FOR MOLECULAR GENETICS   (Germany)

Author keywords

Antibiotics; Drug; Lincomycin; Macrolides; Protein synthesis; Ribosome; Streptogramin

Indexed keywords

ANTIBIOTIC AGENT; AZITHROMYCIN; CLARITHROMYCIN; CLINDAMYCIN; DALFOPRISTIN; ERYTHROMYCIN; KETOLIDE; LINCOMYCIN; LINCOSAMIDE DERIVATIVE; MACROLIDE; MIKAMYCIN B; QUINUPRISTIN; RIBOSOME PROTEIN; RIBOSOME RNA; ROXITHROMYCIN; STREPTOGRAMIN DERIVATIVE; TELITHROMYCIN; TYLOSIN; VERNAMYCIN; VIRGINIAMYCIN M; VIRGINIAMYCIN S;

BINDING AFFINITY; COMPARATIVE STUDY; CRYSTAL STRUCTURE; DEINOCOCCUS RADIODURANS; DRUG BINDING SITE; HALOARCULA MARISMORTUI; MOLECULAR INTERACTION; NONHUMAN; PRIORITY JOURNAL; REVIEW; RIBOSOME; SPECIES DIFFERENCE; STRUCTURE ANALYSIS;

AMINO ACID SEQUENCE; ANTI-BACTERIAL AGENTS; BASE SEQUENCE; BINDING SITES; DEINOCOCCUS; DRUG RESISTANCE, BACTERIAL; HALOARCULA MARISMORTUI; KETOLIDES; MACROLIDES; MOLECULAR SEQUENCE DATA; MOLECULAR STRUCTURE; RIBOSOMES; RNA, RIBOSOMAL; SPECIES SPECIFICITY; STREPTOGRAMINS;

ARCHAEA; BACTERIA (MICROORGANISMS); DEINOCOCCUS RADIODURANS; HALOARCULA MARISMORTUI;

EID: 29044436081     PISSN: 14316730     EISSN: 14374315     Source Type: Journal    
DOI: 10.1515/BC.2005.141     Document Type: Review

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