Structural basis for the antibiotic activity of ketolides and azalides

Structure

Volumn 11, Issue 3, 2003, Pages 329-338

  Schlünzen, Frank ^a   Harms, Jörg M ^a   Franceschi, Francois ^c,d   Hansen, Harly A S ^a   Bartels, Heike ^a   Zarivach, Raz ^a   Yonath, Ada ^a,b  

^a MAX PLANCK UNIT FOR STRUCTURAL MOLECULAR BIOLOGY   (Germany)

^b WEIZMANN INSTITUTE OF SCIENCE   (Israel)

^c MAX PLANCK INSTITUTE FOR MOLECULAR GENETICS   (Germany)

^d Rib X Pharmaceuticals Incorporated   (United States)

Author keywords

Antibiotics; Azalides; Azithromycin; Ketolides; Peptidyl transferase center; Ribosome

Indexed keywords

ANTIBIOTIC AGENT; AZIDE; AZITHROMYCIN; CETHROMYCIN; ERYTHROMYCIN; KETOLIDE; MACROLIDE;

ANTIMICROBIAL ACTIVITY; ARTICLE; CHEMICAL MODIFICATION; CRYSTAL STRUCTURE; CRYSTALLOGRAPHY; DEINOCOCCUS RADIODURANS; DRUG BINDING; DRUG PROTEIN BINDING; INHIBITION KINETICS; NONHUMAN; PATHOGENESIS; PENICILLIN RESISTANCE; PRIORITY JOURNAL; RIBOSOME; RIBOSOME SUBUNIT; STRUCTURE ACTIVITY RELATION; X RAY DIFFRACTION;

ANTI-BACTERIAL AGENTS; AZITHROMYCIN; ERYTHROMYCIN; KETOLIDES; RIBOSOMES; RNA, RIBOSOMAL; STRUCTURE-ACTIVITY RELATIONSHIP;

DEINOCOCCUS RADIODURANS;

EID: 0037334850     PISSN: 09692126     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0969-2126(03)00022-4     Document Type: Article

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