Structure of the A site of Escherichia coli 16S ribosomal RNA complexed with an aminoglycoside antibiotic

Science

Volumn 274, Issue 5291, 1996, Pages 1367-1371

  Fourmy, Dominique ^a   Recht, Michael I ^a   Blanchard, Scott C ^a   Puglisi, Joseph D ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINOGLYCOSIDE ANTIBIOTIC AGENT; PAROMOMYCIN; RNA 16S;

ANTIMICROBIAL ACTIVITY; ARTICLE; DRUG BINDING; ESCHERICHIA COLI; METHYLATION; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; RNA BINDING; RNA TRANSLATION;

ANTI-BACTERIAL AGENTS; BASE COMPOSITION; BINDING SITES; ESCHERICHIA COLI; HYDROGEN BONDING; MAGNETIC RESONANCE SPECTROSCOPY; METHYLATION; MODELS, MOLECULAR; NUCLEIC ACID CONFORMATION; OLIGORIBONUCLEOTIDES; PAROMOMYCIN; RIBOSOMES; RNA, BACTERIAL; RNA, RIBOSOMAL, 16S;

ESCHERICHIA COLI; PROKARYOTA;

EID: 0029825658     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.274.5291.1367     Document Type: Article

References (46)

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46. We thank H. Noller for encouragement and discussions, A. Pardi for assistance with NMR techniques, E. V. Puglisi for comments and support, and M. Ares and R. Green for reading the manuscript. Supported by grants from the Packard Foundation, the Deafness Research Foundation, National Institute of Health (GM51266-01A1), Lucille P, Markey Charitable Trust (J.D.P.), and a postdoctoral grant from Institut National de la Santé et de la Recherche Médicale (D.F.), The coordinates have been deposited in the Brookhaven Protein Data Bank with access number T9496.