-
1
-
-
0026468180
-
A nuclear factor induced by hypoxia via de novo protein synthesis binds to the human erythropoietin gene enhancer at a site required for transcriptional activation
-
Semenza GL, Wang GL: A nuclear factor induced by hypoxia via de novo protein synthesis binds to the human erythropoietin gene enhancer at a site required for transcriptional activation. Mol Cell Biol 1992;12:5447-5454.
-
(1992)
Mol Cell Biol
, vol.12
, pp. 5447-5454
-
-
Semenza, G.L.1
Wang, G.L.2
-
3
-
-
0142182781
-
HIF-1: An oxygen response sys3 tem with special relevance to the kidney
-
Maxwell PH: HIF-1: An oxygen response sys3 tem with special relevance to the kidney. J Am Soc Nephrol 2003;14:2712-2722.
-
(2003)
J Am Soc Nephrol
, vol.14
, pp. 2712-2722
-
-
Maxwell, P.H.1
-
4
-
-
0036037635
-
From erythropoietin to oxygen: Hypoxia-inducible factor hydroxylases and the hypoxia signal pathway
-
Ratcliffe PJ: From erythropoietin to oxygen: hypoxia-inducible factor hydroxylases and the hypoxia signal pathway. Blood Purif 2002;20:445-450.
-
(2002)
Blood Purif
, vol.20
, pp. 445-450
-
-
Ratcliffe, P.J.1
-
5
-
-
0036320934
-
2- regulated gene expression
-
2- regulated gene expression. FASEB J 2002;16:1151-1162.
-
(2002)
FASEB J
, vol.16
, pp. 1151-1162
-
-
Wenger, R.H.1
-
6
-
-
0042368882
-
The hypoxia-inducible factors: Key transcriptional regulators of hypoxic responses
-
Bracken CP, Whitelaw ML, Peet DJ: The hypoxia-inducible factors: key transcriptional regulators of hypoxic responses. Cell Mol Life Sci 2003;60:1376-1393.
-
(2003)
Cell Mol Life Sci
, vol.60
, pp. 1376-1393
-
-
Bracken, C.P.1
Whitelaw, M.L.2
Peet, D.J.3
-
7
-
-
0037337763
-
Oxygen-dependent regulation of hypoxia-inducible factors by prolyl and asparaginyl hydroxylation
-
Lando D, Gorman JJ, Whitelaw ML, Peet DJ: Oxygen-dependent regulation of hypoxia-inducible factors by prolyl and asparaginyl hydroxylation. Eur J Biochem 2003;270:781-790.
-
(2003)
Eur J Biochem
, vol.270
, pp. 781-790
-
-
Lando, D.1
Gorman, J.J.2
Whitelaw, M.L.3
Peet, D.J.4
-
8
-
-
1642387020
-
Hypoxia-inducible factor (HIF-1)α: Its protein stability and biologic functions
-
Lee JW, Bae SH, Jeong JW, Kim SH, Kim KW: Hypoxia-inducible factor (HIF-1)α: its protein stability and biologic functions. Exp Mol Med 2004;36:1-12.
-
(2004)
Exp Mol Med
, vol.36
, pp. 1-12
-
-
Lee, J.W.1
Bae, S.H.2
Jeong, J.W.3
Kim, S.H.4
Kim, K.W.5
-
9
-
-
3843095197
-
HIF-1's relationship to oxygen: Simple yet sophisticated
-
Maxwell PH: HIF-1's relationship to oxygen: simple yet sophisticated. Cell Cycle 2004;3:156-159.
-
(2004)
Cell Cycle
, vol.3
, pp. 156-159
-
-
Maxwell, P.H.1
-
10
-
-
2542450917
-
HIF hydroxylation and cellular oxygen sensing
-
Metzen E, Ratcliffe PJ: HIF hydroxylation and cellular oxygen sensing. Biol Chem 2004;385:223-230.
-
(2004)
Biol Chem
, vol.385
, pp. 223-230
-
-
Metzen, E.1
Ratcliffe, P.J.2
-
11
-
-
8344237449
-
Hydroxylation of HIF-1: Oxygen sensing at the molecular level
-
Semenza GL: Hydroxylation of HIF-1: oxygen sensing at the molecular level. Physiology 2004;19:176-182.
-
(2004)
Physiology
, vol.19
, pp. 176-182
-
-
Semenza, G.L.1
-
12
-
-
0345491599
-
Differential roles of hypoxia-inducible factor 1α (HIF-1α) and HIF-2α in hypoxic gene regulation
-
Hu CJ, Wang LY, Chodosh LA, Keith B, Simon MC: Differential roles of hypoxia-inducible factor 1α (HIF-1α) and HIF-2α in hypoxic gene regulation. Mol Cell Biol 2003;23:9361-9374.
-
(2003)
Mol Cell Biol
, vol.23
, pp. 9361-9374
-
-
Hu, C.J.1
Wang, L.Y.2
Chodosh, L.A.3
Keith, B.4
Simon, M.C.5
-
13
-
-
9444283176
-
Differentiating the functional role of hypoxia-inducible factor (HIF)-1alpha and HIF-2alpha (EPAS-1) by the use of RNA interference: Erythropoietin is a HIF-2alpha target gene in Hep3B and Kelly cells
-
Warnecke C, Zaborowska Z, Kurreck J, Erdmann VA, Frei U, Wiesener M, Eckardt KU: Differentiating the functional role of hypoxia-inducible factor (HIF)-1alpha and HIF-2alpha (EPAS-1) by the use of RNA interference: erythropoietin is a HIF-2alpha target gene in Hep3B and Kelly cells. FASEB J 2004;18:1462-1464.
-
(2004)
FASEB J
, vol.18
, pp. 1462-1464
-
-
Warnecke, C.1
Zaborowska, Z.2
Kurreck, J.3
Erdmann, V.A.4
Frei, U.5
Wiesener, M.6
Eckardt, K.U.7
-
14
-
-
0035917313
-
2 sensing
-
2 sensing. Science 2001;292:464-468.
-
(2001)
Science
, vol.292
, pp. 464-468
-
-
Ivan, M.1
Kondo, K.2
Yang, H.3
Kim, W.4
Valiando, J.5
Ohh, M.6
Salic, A.7
Asara, J.M.8
Lane, W.S.9
Kaelin Jr., W.G.10
-
15
-
-
0035917808
-
Targeting of HIFalpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation
-
Jaakkola P, Mole DR, Tian YM, Wilson MI, Gielbert J, Gaskell SJ, Kriegsheim A, Hebestreit HF, Mukherji M, Schofield CJ, Maxwell PH, Pugh CW, Ratcliffe PJ: Targeting of HIFalpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation. Science 2001;292:468-472.
-
(2001)
Science
, vol.292
, pp. 468-472
-
-
Jaakkola, P.1
Mole, D.R.2
Tian, Y.M.3
Wilson, M.I.4
Gielbert, J.5
Gaskell, S.J.6
Kriegsheim, A.7
Hebestreit, H.F.8
Mukherji, M.9
Schofield, C.J.10
Maxwell, P.H.11
Pugh, C.W.12
Ratcliffe, P.J.13
-
16
-
-
0035887011
-
FIH-I: A novel protein that interacts with HIF-1alpha and VHL to mediate repression of HIF-1 transcriptionalactivity
-
Mahon PC, Hirota K, Semenza GL: FIH-I : A novel protein that interacts with HIF-1alpha and VHL to mediate repression of HIF-1 transcriptionalactivity. Genes Dev 2001;15:2675-2686.
-
(2001)
Genes Dev
, vol.15
, pp. 2675-2686
-
-
Mahon, P.C.1
Hirota, K.2
Semenza, G.L.3
-
17
-
-
18544386401
-
Hypoxia-inducible factor (HIF) asparagine hydroxylase is identical to factor inhibiting HIF (FIH) and is related to the cupin structural family
-
Hewitson KS, McNeill LA, Riordan MV, Tian YM, Bullock AN, Welford RW, Elkins JM, Oldham NJ, Bhattacharya S, Gleadle JM, Ratcliffe PJ, Pugh CW, Schofield CJ: Hypoxia-inducible factor (HIF) asparagine hydroxylase is identical to factor inhibiting HIF (FIH) and is related to the cupin structural family. J Biol Chem 2002;277:26351-26355.
-
(2002)
J Biol Chem
, vol.277
, pp. 26351-26355
-
-
Hewitson, K.S.1
McNeill, L.A.2
Riordan, M.V.3
Tian, Y.M.4
Bullock, A.N.5
Welford, R.W.6
Elkins, J.M.7
Oldham, N.J.8
Bhattacharya, S.9
Gleadle, J.M.10
Ratcliffe, P.J.11
Pugh, C.W.12
Schofield, C.J.13
-
18
-
-
17944375360
-
C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation
-
Epstein AC, Gleadle JM, McNeill LA, Hewitson KS, O'Rourke J, Mole DR, Mukherji M, Metzen E, Wilson MI, Dhanda A, Tian YM, Masson N, Hamilton DL, Jaakkola P, Barstead R, Hodgkin J, Maxwel PH, Pugh CW, Schofield CJ, Ratcliffe PJ: C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation. Cell 2001;107:43-54.
-
(2001)
Cell
, vol.107
, pp. 43-54
-
-
Epstein, A.C.1
Gleadle, J.M.2
McNeill, L.A.3
Hewitson, K.S.4
O'Rourke, J.5
Mole, D.R.6
Mukherji, M.7
Metzen, E.8
Wilson, M.I.9
Dhanda, A.10
Tian, Y.M.11
Masson, N.12
Hamilton, D.L.13
Jaakkola, P.14
Barstead, R.15
Hodgkin, J.16
Maxwel, P.H.17
Pugh, C.W.18
Schofield, C.J.19
Ratcliffe, P.J.20
more..
-
19
-
-
0035834409
-
A conserved family of prolyl-4-hydroxylases that modify HIF
-
Bruick RK, McKnight SL: A conserved family of prolyl-4-hydroxylases that modify HIF. Science 2001;294:1337-1340.
-
(2001)
Science
, vol.294
, pp. 1337-1340
-
-
Bruick, R.K.1
McKnight, S.L.2
-
20
-
-
0041465022
-
HIF prolyl-hydroxylase 2 is the key oxygen sensor setting low steady-state levels of HIF-1 alpha in normoxia
-
Berra E, Benizri E, Ginouves A, Volmat V, Roux D, Pouyssegur J: HIF prolyl-hydroxylase 2 is the key oxygen sensor setting low steady-state levels of HIF-1 alpha in normoxia. EMBO J 2003;22:4082-4090.
-
(2003)
EMBO J
, vol.22
, pp. 4082-4090
-
-
Berra, E.1
Benizri, E.2
Ginouves, A.3
Volmat, V.4
Roux, D.5
Pouyssegur, J.6
-
21
-
-
4344645563
-
Hypoxia-inducible factor-1 (HIF-1) promotes its degradation by induction of HIF-alpha-prolyl-4-hydroxylases
-
Marxsen JH, Stengel P, Doege K, Heikkinen P, Jokilehto P, Wagner T, Jelkmann W, Jaakkola P, Metzen E: Hypoxia-inducible factor-1 (HIF-1) promotes its degradation by induction of HIF-alpha-prolyl-4-hydroxylases. Biochem J 2004;381:761-767.
-
(2004)
Biochem J
, vol.381
, pp. 761-767
-
-
Marxsen, J.H.1
Stengel, P.2
Doege, K.3
Heikkinen, P.4
Jokilehto, P.5
Wagner, T.6
Jelkmann, W.7
Jaakkola, P.8
Metzen, E.9
-
22
-
-
4644318828
-
Differential function of the prolyl hydroxylases PHD1, PHD2, and PHD3 in the regulation of hypoxia-inducible factor
-
Appelhoff RJ, Tian YM, Raval RR, Turley H, Harris AL, Pugh CW, Ratcliffe PJ, Gleadle JM: Differential function of the prolyl hydroxylases PHD1, PHD2, and PHD3 in the regulation of hypoxia-inducible factor. J Biol Chem 2004;279:38458-38465.
-
(2004)
J Biol Chem
, vol.279
, pp. 38458-38465
-
-
Appelhoff, R.J.1
Tian, Y.M.2
Raval, R.R.3
Turley, H.4
Harris, A.L.5
Pugh, C.W.6
Ratcliffe, P.J.7
Gleadle, J.M.8
-
23
-
-
0043234538
-
Characterization of the human prolyl 4-hydroxylases that modify the hypoxia-inducible factor
-
Hirsilä M, Koivunen P, Günzler V, Kivirikko KI, Myllyharju J: Characterization of the human prolyl 4-hydroxylases that modify the hypoxia-inducible factor. J Biol Chem 2003;78:30772-30780.
-
(2003)
J Biol Chem
, vol.78
, pp. 30772-30780
-
-
Hirsilä, M.1
Koivunen, P.2
Günzler, V.3
Kivirikko, K.I.4
Myllyharju, J.5
-
24
-
-
0037097861
-
FIH-1 is an asparaginyl hydroxylase enzyme that regulates the transcriptional activity of hypoxia-inducible factor
-
Lando D, Peet DJ, Gorman JJ; Whelan DA, Whitelaw ML, Bruick RK: FIH-1 is an asparaginyl hydroxylase enzyme that regulates the transcriptional activity of hypoxia-inducible factor. Genes Dev 2002;16:1466-1471.
-
(2002)
Genes Dev
, vol.16
, pp. 1466-1471
-
-
Lando, D.1
Peet, D.J.2
Gorman, J.J.3
Whelan, D.A.4
Whitelaw, M.L.5
Bruick, R.K.6
-
25
-
-
1642315195
-
Catalytic properties of the asparaginyl hydroxylase (FIH) in the oxygen sensing pathway are distinct from those of its prolyl 4-hydroxylases
-
Koivunen P, Hirsilä M, Günzler V, Kivirikko KI. Myllyharju J: Catalytic properties of the asparaginyl hydroxylase (FIH) in the oxygen sensing pathway are distinct from those of its prolyl 4-hydroxylases. J Biol Chem 2004;279:9899-9904.
-
(2004)
J Biol Chem
, vol.279
, pp. 9899-9904
-
-
Koivunen, P.1
Hirsilä, M.2
Günzler, V.3
Kivirikko, K.I.4
Myllyharju, J.5
-
26
-
-
0038825680
-
2-Oxoglutarate analogue inhibitors of HIF prolyl hydroxylase
-
Mole DR, Schlemminger I, McNeill LA, Hewitson KS, Pugh CW, Ratcliffe PJ, Schofield CJ: 2-oxoglutarate analogue inhibitors of HIF prolyl hydroxylase. Bioorg Med Chem Lett 2003;13:2677-2680.
-
(2003)
Bioorg Med Chem Lett
, vol.13
, pp. 2677-2680
-
-
Mole, D.R.1
Schlemminger, I.2
McNeill, L.A.3
Hewitson, K.S.4
Pugh, C.W.5
Ratcliffe, P.J.6
Schofield, C.J.7
-
28
-
-
7644229277
-
Translation of ischemic preconditioning to the patient: Prolyl hydroxylase inhibition and hypoxia inducible factor-1 as a novel target for stroke therapy
-
Ratan RR, Siddiq A, Aminova L, Lange PS, Langley B, Ayoub I, Gensert JA, Chavez J: Translation of ischemic preconditioning to the patient: prolyl hydroxylase inhibition and hypoxia inducible factor-1 as a novel target for stroke therapy. Stroke 2004;35(suppl):2687-2689.
-
(2004)
Stroke
, vol.35
, Issue.SUPPL.
, pp. 2687-2689
-
-
Ratan, R.R.1
Siddiq, A.2
Aminova, L.3
Lange, P.S.4
Langley, B.5
Ayoub, I.6
Gensert, J.A.7
Chavez, J.8
-
29
-
-
0024273450
-
Regulation of the erythropoietin gene: Evidence that the oxygen sensor is a heme protein
-
Goldberg MA, Dunning SP, Bunn HF: Regulation of the erythropoietin gene: Evidence that the oxygen sensor is a heme protein. Science 1988;242:1412-1415.
-
(1988)
Science
, vol.242
, pp. 1412-1415
-
-
Goldberg, M.A.1
Dunning, S.P.2
Bunn, H.F.3
-
30
-
-
0024639221
-
Protein hydroxylation: Prolyl 4-hydroxylase, an enzyme with four cosubstrates and a multi-functional subunit
-
Kivirikko KI, Myllyla R, Pihlajaniemi T: Protein hydroxylation: Prolyl 4-hydroxylase, an enzyme with four cosubstrates and a multi-functional subunit. FASEB J 1989;3:1609-1617.
-
(1989)
FASEB J
, vol.3
, pp. 1609-1617
-
-
Kivirikko, K.I.1
Myllyla, R.2
Pihlajaniemi, T.3
-
31
-
-
4644260710
-
Depletion of intracellular ascorbate by the carcinogenic metals nickel and cobalt results in the induction of hypoxic stress
-
Salnikow K, Donald SP, Bruick RK, Zhitkovich A, Phang JM, Kasprzak KS: Depletion of intracellular ascorbate by the carcinogenic metals nickel and cobalt results in the induction of hypoxic stress. J Biol Chem 2004;279:40337-40344.
-
(2004)
J Biol Chem
, vol.279
, pp. 40337-40344
-
-
Salnikow, K.1
Donald, S.P.2
Bruick, R.K.3
Zhitkovich, A.4
Phang, J.M.5
Kasprzak, K.S.6
-
32
-
-
23044452937
-
Accumulation of hypoxia-inducible factor-1 is limited by transcription-dependent depletion
-
Demidenko ZN, Rapisarda AM, Garayoa M, Giannakakou P, Melillo G, Blagosklonny M: Accumulation of hypoxia-inducible factor-1 is limited by transcription-dependent depletion. Oncogene 2005;24:4829-4838.
-
(2005)
Oncogene
, vol.24
, pp. 4829-4838
-
-
Demidenko, Z.N.1
Rapisarda, A.M.2
Garayoa, M.3
Giannakakou, P.4
Melillo, G.5
Blagosklonny, M.6
-
33
-
-
4944246547
-
The role of hypoxia inducible factor 1 (HIF-1) in hypoxia induced apoptosis
-
Greijer AE, van der Wall E: The role of hypoxia inducible factor 1 (HIF-1) in hypoxia induced apoptosis. J Clin Pathol 2004;57:1009-1014.
-
(2004)
J Clin Pathol
, vol.57
, pp. 1009-1014
-
-
Greijer, A.E.1
Van Der Wall, E.2
-
34
-
-
16644363476
-
HIF-1 and p53: Communication of transcription factors under hypoxia
-
Schmidt T, Zou J, Brüne B: HIF-1 and p53: communication of transcription factors under hypoxia. J Cell Mol Med 2004;8:423-431.
-
(2004)
J Cell Mol Med
, vol.8
, pp. 423-431
-
-
Schmidt, T.1
Zou, J.2
Brüne, B.3
-
35
-
-
0035855668
-
Dephosphorylated hypoxia-inducible factor 1alpha as a mediator of p53-dependent apoptosis during hypoxia
-
Suzuki H, Tomida A, Tsuruo T: Dephosphorylated hypoxia-inducible factor 1alpha as a mediator of p53-dependent apoptosis during hypoxia. Oncogene 2001;20:5779-5788.
-
(2001)
Oncogene
, vol.20
, pp. 5779-5788
-
-
Suzuki, H.1
Tomida, A.2
Tsuruo, T.3
-
36
-
-
0036216692
-
HIF-1 and tumor progression: Pathophysiology and therapeutics
-
Semenza GL: HIF-1 and tumor progression: pathophysiology and therapeutics. Trends Mol Med 2002;8(4 suppl):S62-S67.
-
(2002)
Trends Mol Med
, vol.8
, Issue.4 SUPPL.
-
-
Semenza, G.L.1
-
38
-
-
21344474796
-
Review: Hypoxia-inducible factor-1 (HIF-1): A novel transcription factor in immune reactions
-
Hellwig-Burgel T, Stiehl DP, Wagner AE, Metzen E, Jelkmann V: Review: Hypoxia-inducible factor-1 (HIF-1): A novel transcription factor in immune reactions. J Interferon Cytokine Res 2005;25:297-310.
-
(2005)
J Interferon Cytokine Res
, vol.25
, pp. 297-310
-
-
Hellwig-Burgel, T.1
Stiehl, D.P.2
Wagner, A.E.3
Metzen, E.4
Jelkmann, V.5
-
39
-
-
22144493866
-
Negative and positive regulation of HIF-1: A complex network
-
Bardos J, Ashcroft M: Negative and positive regulation of HIF-1: a complex network. Biochim Biophys Acta 2005;1755:107-120.
-
(2005)
Biochim Biophys Acta
, vol.1755
, pp. 107-120
-
-
Bardos, J.1
Ashcroft, M.2
-
40
-
-
4644239244
-
Mammalian target of rapamycin inhibition
-
Dutcher JP: Mammalian target of rapamycin inhibition. Clin Cancer Res 2004;10:6382S-6387S.
-
(2004)
Clin Cancer Res
, vol.10
-
-
Dutcher, J.P.1
-
41
-
-
0346848743
-
Sirolimus delays recovery of rat kidney transplants after ischemia-reperfusion injury
-
Fuller TF, Preise CE, Serkova N, Niemann CU, Olson JL, Feng S: Sirolimus delays recovery of rat kidney transplants after ischemia-reperfusion injury. Transplantation 2003;76:1594-1599.
-
(2003)
Transplantation
, vol.76
, pp. 1594-1599
-
-
Fuller, T.F.1
Preise, C.E.2
Serkova, N.3
Niemann, C.U.4
Olson, J.L.5
Feng, S.6
-
42
-
-
0347334750
-
IL-1b mediated up-regulation of HIF-1α via an NF-kB/COX2 pathway identifies HIF as a critical link between inflammation and oncogenesis
-
Jung YJ, Isaacs JS, Lee S, Trepel J, Neckers L: IL-1b mediated up-regulation of HIF-1α via an NF-kB/COX2 pathway identifies HIF as a critical link between inflammation and oncogenesis. FASEB J 2003;17:2115-2117.
-
(2003)
FASEB J
, vol.17
, pp. 2115-2117
-
-
Jung, Y.J.1
Isaacs, J.S.2
Lee, S.3
Trepel, J.4
Neckers, L.5
-
43
-
-
0037444823
-
Hypoxia-inducible factor induction by tumour necrosis factor in normoxic cells requires receptor-interacting protein-dependent nuclear factor kappa B activation
-
Jung Y, Isaacs JS, Lee S, Trepel J, Liu ZG, Neckers L: Hypoxia-inducible factor induction by tumour necrosis factor in normoxic cells requires receptor-interacting protein-dependent nuclear factor kappa B activation. Biochem J 2003;370(Pt 3):1011-1017.
-
(2003)
Biochem J
, vol.370
, Issue.3 PART
, pp. 1011-1017
-
-
Jung, Y.1
Isaacs, J.S.2
Lee, S.3
Trepel, J.4
Liu, Z.G.5
Neckers, L.6
-
44
-
-
0038308573
-
Tumor necrosis factor-α causes accumulation of a ubiquitinated form of hypoxia inducible factor-1α through a nuclear factor-kB-dependent pathway
-
Zhou J, Schmidt T, Brüne B: Tumor necrosis factor-α causes accumulation of a ubiquitinated form of hypoxia inducible factor-1α through a nuclear factor-kB-dependent pathway. Mol Biol Cell 2003;14:2216-2225.
-
(2003)
Mol Biol Cell
, vol.14
, pp. 2216-2225
-
-
Zhou, J.1
Schmidt, T.2
Brüne, B.3
-
45
-
-
22044440743
-
Angiotensin II stimulates hypoxia-inducible factor 1a accumulation in glomerular mesangial cells
-
Chen TH, Wang JF, Chan P, Lee HM: Angiotensin II stimulates hypoxia-inducible factor 1a accumulation in glomerular mesangial cells. Ann NY Acad Sci 2005;1042:286-293.
-
(2005)
Ann NY Acad Sci
, vol.1042
, pp. 286-293
-
-
Chen, T.H.1
Wang, J.F.2
Chan, P.3
Lee, H.M.4
-
46
-
-
2442485795
-
Follicle-stimulating hormone activation of hypoxia-inducible factor-1 by the phosphatidylinositol 3-kinase/Akt/Ras homolog enriched in brain (Rheb)/mammalian target of rapamycin (mTOR) pathway is necessary for induction of select protein markers of follicular differentiation
-
Alam H, Maizels ET, Park Y, Ghaey S, Feigert ZJ, Chandel NS, Hunzicker-Dunn M: Follicle-stimulating hormone activation of hypoxia-inducible factor-1 by the phosphatidylinositol 3-kinase/Akt/Ras homolog enriched in brain (Rheb)/mammalian target of rapamycin (mTOR) pathway is necessary for induction of select protein markers of follicular differentiation. J Biol Chem 2004;279:19431-19440.
-
(2004)
J Biol Chem
, vol.279
, pp. 19431-19440
-
-
Alam, H.1
Maizels, E.T.2
Park, Y.3
Ghaey, S.4
Feigert, Z.J.5
Chandel, N.S.6
Hunzicker-Dunn, M.7
-
47
-
-
0037064010
-
Insulin-like growth factor 1 induces hypoxia-inducible factor 1-mediated vascular endothelial growth factor expression, which is dependent on MAP kinase and phosphatidylinositol 3-kinase signaling in colon cancer cells
-
Fukuda R, Hirota K, Fan F, Jung YD, Ellis LM, Semenza GL: Insulin-like growth factor 1 induces hypoxia-inducible factor 1-mediated vascular endothelial growth factor expression, which is dependent on MAP kinase and phosphatidylinositol 3-kinase signaling in colon cancer cells. J Biol Chem 2002;277:38205-38211.
-
(2002)
J Biol Chem
, vol.277
, pp. 38205-38211
-
-
Fukuda, R.1
Hirota, K.2
Fan, F.3
Jung, Y.D.4
Ellis, L.M.5
Semenza, G.L.6
-
48
-
-
4744365128
-
Induction of hypoxia-inducible factor 1 activity by muscarinic acetylcholine receptor signaling
-
Hirota K, Fukuda R, Takabuchi S, Kizaka-Kondoh S, Adachi T, Fukuda K, Semenza GL: Induction of hypoxia-inducible factor 1 activity by muscarinic acetylcholine receptor signaling. J Biol Chem 2004;279:41521-41528.
-
(2004)
J Biol Chem
, vol.279
, pp. 41521-41528
-
-
Hirota, K.1
Fukuda, R.2
Takabuchi, S.3
Kizaka-Kondoh, S.4
Adachi, T.5
Fukuda, K.6
Semenza, G.L.7
-
49
-
-
1642453685
-
Nitric oxide induces hypoxia-inducible factor 1 activation that is dependent on MAPK and phosphatidylinositol 3-kinase signaling
-
Kasuno K, Takabuchi S, Fukuda K, Kizaka-Kondoh S, Yodoi J, Adachi T, Semenza GL, Hirota K: Nitric oxide induces hypoxia-inducible factor 1 activation that is dependent on MAPK and phosphatidylinositol 3-kinase signaling. J Biol Chem 2004;279:2550-2558.
-
(2004)
J Biol Chem
, vol.279
, pp. 2550-2558
-
-
Kasuno, K.1
Takabuchi, S.2
Fukuda, K.3
Kizaka-Kondoh, S.4
Yodoi, J.5
Adachi, T.6
Semenza, G.L.7
Hirota, K.8
-
51
-
-
4143126432
-
Thyroid hormone induces erythropoietin gene expression through augmented accumulation of hypoxia-inducible factor-1
-
Ma Y, Freitag P, Zhou J, Brüne B, Frede S, Fandrey J: Thyroid hormone induces erythropoietin gene expression through augmented accumulation of hypoxia-inducible factor-1. Am J Physiol 2004;287:R600-R607.
-
(2004)
Am J Physiol
, vol.287
-
-
Ma, Y.1
Freitag, P.2
Zhou, J.3
Brüne, B.4
Frede, S.5
Fandrey, J.6
-
52
-
-
0034282553
-
The Kaposi's sarcoma-associated herpes virus G protein-coupled receptor up-regulates vascular endothelial growth factor expression and secretion through mitogen-activated protein kinase and p38 pathways acting on hypoxia-inducible factor 1alpha
-
Sodhi A, Montaner S, Patel V, Zohar M, Bais C, Mesri EA, Gutkind JS: The Kaposi's sarcoma-associated herpes virus G protein-coupled receptor up-regulates vascular endothelial growth factor expression and secretion through mitogen-activated protein kinase and p38 pathways acting on hypoxia-inducible factor 1alpha. Cancer Res 2000;60:4873-4880.
-
(2000)
Cancer Res
, vol.60
, pp. 4873-4880
-
-
Sodhi, A.1
Montaner, S.2
Patel, V.3
Zohar, M.4
Bais, C.5
Mesri, E.A.6
Gutkind, J.S.7
-
53
-
-
2542443138
-
Epstein-Barr virus latent membrane protein 1 induces synthesis of hypoxia-inducible factor 1 alpha
-
Wakisaka N, Kondo S, Yoshizaki T, Murono S, Furukawa M, Pagano JS: Epstein-Barr virus latent membrane protein 1 induces synthesis of hypoxia-inducible factor 1 alpha. Mol Cell Biol 2004;24:5223-5234.
-
(2004)
Mol Cell Biol
, vol.24
, pp. 5223-5234
-
-
Wakisaka, N.1
Kondo, S.2
Yoshizaki, T.3
Murono, S.4
Furukawa, M.5
Pagano, J.S.6
-
54
-
-
0141532010
-
Hepatitis B virus X protein enhances transcriptional activity of hypoxia-inducible factor-1alpha through activation of mitogen-activated protein kinase pathway
-
Yoo YG, Oh SH, Park ES, ChoiH, Lee N, Park H, Kim DK, Yu DY, Seong JK, Lee MO: Hepatitis B virus X protein enhances transcriptional activity of hypoxia-inducible factor-1alpha through activation of mitogen-activated protein kinase pathway. J Biol Chem 2003;278:39076-39084.
-
(2003)
J Biol Chem
, vol.278
, pp. 39076-39084
-
-
Yoo, Y.G.1
Oh, S.H.2
Park, E.S.3
Choi, H.4
Lee, N.5
Park, H.6
Kim, D.K.7
Yu, D.Y.8
Seong, J.K.9
Lee, M.O.10
-
55
-
-
0038688765
-
Cyclosporin A prevents the hypoxic adaptation by activating hypoxia-inducible factor-1α Pro-564 hydroxylation
-
D'Angelo G, Duplan E, Vigne P, Frelin C: Cyclosporin A prevents the hypoxic adaptation by activating hypoxia-inducible factor-1α Pro-564 hydroxylation. J Biol Chem 2003;278:15406-15411.
-
(2003)
J Biol Chem
, vol.278
, pp. 15406-15411
-
-
D'Angelo, G.1
Duplan, E.2
Vigne, P.3
Frelin, C.4
-
56
-
-
3342955379
-
Novel mechanism of action for hydralazine: Induction of hypoxia-inducible factor-1a, vascular endothelial growth factor, and angiogenesis by inhibition of prolyl hydroxylases
-
Knowles HJ, Tian YM, Mole DR, Harris AL: Novel mechanism of action for hydralazine: induction of hypoxia-inducible factor-1a, vascular endothelial growth factor, and angiogenesis by inhibition of prolyl hydroxylases. Circ Res 2004;95:162-169.
-
(2004)
Circ Res
, vol.95
, pp. 162-169
-
-
Knowles, H.J.1
Tian, Y.M.2
Mole, D.R.3
Harris, A.L.4
-
57
-
-
7244242390
-
Chelation of cellular calcium modulates hypoxia-inducible gene expression through activation of hypoxia-inducible factor-1α
-
Berchner-Pfannschmidt U, Petrat F, Doege K, Trinidad B, Freitag P, Metzen E, de Groot H, Fandrey J: Chelation of cellular calcium modulates hypoxia-inducible gene expression through activation of hypoxia-inducible factor-1α. J Biol Chem 2004;279:44976-44986.
-
(2004)
J Biol Chem
, vol.279
, pp. 44976-44986
-
-
Berchner-Pfannschmidt, U.1
Petrat, F.2
Doege, K.3
Trinidad, B.4
Freitag, P.5
Metzen, E.6
De Groot, H.7
Fandrey, J.8
-
58
-
-
4644317883
-
Hypoxic reduction in cellular glutathione levels requires mitochondrial reactive oxygen species
-
Mansfield KD, Simon MS, Keith B: Hypoxic reduction in cellular glutathione levels requires mitochondrial reactive oxygen species. J Appl Physiol 2004;97:1358-1366.
-
(2004)
J Appl Physiol
, vol.97
, pp. 1358-1366
-
-
Mansfield, K.D.1
Simon, M.S.2
Keith, B.3
-
59
-
-
0034282388
-
Nonhypoxic pathway mediates the induction of hypoxia-inducible factor 1alpha in vascular smooth muscle cells
-
Richard DE, Berra E, Pouyssegur J: Nonhypoxic pathway mediates the induction of hypoxia-inducible factor 1alpha in vascular smooth muscle cells. J Biol Chem 2000;275:26765-26771.
-
(2000)
J Biol Chem
, vol.275
, pp. 26765-26771
-
-
Richard, D.E.1
Berra, E.2
Pouyssegur, J.3
-
60
-
-
0037947590
-
Redox regulation of HIF-1alpha levels and HO-1 expression in renal medullary interstitial cells
-
Yang ZZ, Zhang AY, Yi FX, Li PL, Zou AP: Redox regulation of HIF-1alpha levels and HO-1 expression in renal medullary interstitial cells. Am J Physiol 2003;284:F1207-F1215.
-
(2003)
Am J Physiol
, vol.284
-
-
Yang, Z.Z.1
Zhang, A.Y.2
Yi, F.X.3
Li, P.L.4
Zou, A.P.5
-
61
-
-
0037073695
-
Induction of hypoxia-inducible factor-1alpha by transcriptional and translational mechanisms
-
Page EL, Robitaille GA, Pouyssegur J. Richard DE : Induction of hypoxia-inducible factor-1alpha by transcriptional and translational mechanisms. J Biol Chem 2002;277:48403-48409.
-
(2002)
J Biol Chem
, vol.277
, pp. 48403-48409
-
-
Page, E.L.1
Robitaille, G.A.2
Pouyssegur, J.3
Richard, D.E.4
-
62
-
-
1642581653
-
Hypoxic gene activation by lipopolysaccharide in macrophages: Implication of hypoxia-inducible factor 1alpha
-
Blouin CC, Page EL, Soucy GM, Richard DE: Hypoxic gene activation by lipopolysaccharide in macrophages: implication of hypoxia-inducible factor 1alpha. Blood 2004;103:1124-1130.
-
(2004)
Blood
, vol.103
, pp. 1124-1130
-
-
Blouin, C.C.1
Page, E.L.2
Soucy, G.M.3
Richard, D.E.4
-
63
-
-
0041856168
-
Role of the glucocorticoid receptor for regulation of hypoxia-dependent gene expression
-
Kodama T, Shimizu N, Yoshikawa N, Makino Y, Ouchida R, Okamoto K, Hisada T, Nakamura H, Morimoto C, Tanaka H: Role of the glucocorticoid receptor for regulation of hypoxia-dependent gene expression. J Biol Chem 2003;278:33384-33391.
-
(2003)
J Biol Chem
, vol.278
, pp. 33384-33391
-
-
Kodama, T.1
Shimizu, N.2
Yoshikawa, N.3
Makino, Y.4
Ouchida, R.5
Okamoto, K.6
Hisada, T.7
Nakamura, H.8
Morimoto, C.9
Tanaka, H.10
-
64
-
-
0029858079
-
Identification of hypoxically inducible mRNAs in HeLa cells using differential-display PCR: Role of hypoxia-inducible factor-1
-
O'Rourke JF, Pugh CW, Bartlett SM, Ratcliffe PJ: Identification of hypoxically inducible mRNAs in HeLa cells using differential-display PCR: role of hypoxia-inducible factor-1. Eur J Biochem 1996;241:403-410.
-
(1996)
Eur J Biochem
, vol.241
, pp. 403-410
-
-
O'Rourke, J.F.1
Pugh, C.W.2
Bartlett, S.M.3
Ratcliffe, P.J.4
-
65
-
-
0030611360
-
Characterization of the alpha1B-adrenergic receptor gene promoter region and hypoxia regulatory elements in vascular smooth muscle
-
USA
-
Eckhart AD, Yang N, Xin X, Faber JE: Characterization of the alpha1B-adrenergic receptor gene promoter region and hypoxia regulatory elements in vascular smooth muscle. Proc Natl Acad Sci USA 1997;94:9487-9492.
-
(1997)
Proc Natl Acad Sci
, vol.94
, pp. 9487-9492
-
-
Eckhart, A.D.1
Yang, N.2
Xin, X.3
Faber, J.E.4
-
66
-
-
0032504165
-
Adrenomedullin gene expression is developmentally regulated and induced by hypoxia in rat ventricular cardiac myocytes
-
Cormier-Regard S, Nguyen SV, Claycomb WC: Adrenomedullin gene expression is developmentally regulated and induced by hypoxia in rat ventricular cardiac myocytes. J Biol Chem 1998;273:17787-17792.
-
(1998)
J Biol Chem
, vol.273
, pp. 17787-17792
-
-
Cormier-Regard, S.1
Nguyen, S.V.2
Claycomb, W.C.3
-
67
-
-
0034649507
-
Identification of novel hypoxia dependent and independent target genes of the von Hippel-Lindau (VHL) tumour suppressor by mRNA differential expression profiling
-
Wykoff CC, Pugh CW, Maxwell PH, Harris AL, Ratcliffe PJ: Identification of novel hypoxia dependent and independent target genes of the von Hippel-Lindau (VHL) tumour suppressor by mRNA differential expression profiling. Oncogene 2000;19:6297-6305.
-
(2000)
Oncogene
, vol.19
, pp. 6297-6305
-
-
Wykoff, C.C.1
Pugh, C.W.2
Maxwell, P.H.3
Harris, A.L.4
Ratcliffe, P.J.5
-
68
-
-
0037442536
-
Hypoxic activation of the atrial natriuretic peptide gene promoter through direct and indirect actions of hypoxia-inducible factor-1
-
Chun YS, Hyun JY, Kwak YG, Kim IS, Kim CH, Choi E, Kim MS, Park JW: Hypoxic activation of the atrial natriuretic peptide gene promoter through direct and indirect actions of hypoxia-inducible factor-1. Biochem J 2003;370:149-157.
-
(2003)
Biochem J
, vol.370
, pp. 149-157
-
-
Chun, Y.S.1
Hyun, J.Y.2
Kwak, Y.G.3
Kim, I.S.4
Kim, C.H.5
Choi, E.6
Kim, M.S.7
Park, J.W.8
-
69
-
-
0037374289
-
Regulation of colon carcinoma cell invasion by hypoxia-inducible factor 1
-
Krishnamachary B, Berg-Dixon S, Kelly B, Agani F, Feldser D, Ferreira G, Iyer N, LaRusch J, Pak B, Taghavi P, Semenza GL: Regulation of colon carcinoma cell invasion by hypoxia-inducible factor 1. Cancer Res 2003;63:1138-1143.
-
(2003)
Cancer Res
, vol.63
, pp. 1138-1143
-
-
Krishnamachary, B.1
Berg-Dixon, S.2
Kelly, B.3
Agani, F.4
Feldser, D.5
Ferreira, G.6
Iyer, N.7
LaRusch, J.8
Pak, B.9
Taghavi, P.10
Semenza, G.L.11
-
70
-
-
0028068606
-
Transcriptional regulation of genes encoding glycolytic enzymes by hypoxia-inducible factor 1
-
Semenza GL, Roth PH, Fang HM, Wang GL: Transcriptional regulation of genes encoding glycolytic enzymes by hypoxia-inducible factor 1. J Biol Chem 1994;269:23757-23763.
-
(1994)
J Biol Chem
, vol.269
, pp. 23757-23763
-
-
Semenza, G.L.1
Roth, P.H.2
Fang, H.M.3
Wang, G.L.4
-
71
-
-
0141640863
-
Hypoxia-inducible factor-1 mediates activation of cultured vascular endothelial cells by inducing multiple angiogenic factors
-
Yamakawa M, Liu LX, Date T, Belanger AJ, Vincet KA, Akita GY, Kuriyama T, Cheng SH, Gregory RJ, Jiang C: Hypoxia-inducible factor-1 mediates activation of cultured vascular endothelial cells by inducing multiple angiogenic factors. Circ Res 2003;93:664-673.
-
(2003)
Circ Res
, vol.93
, pp. 664-673
-
-
Yamakawa, M.1
Liu, L.X.2
Date, T.3
Belanger, A.J.4
Vincet, K.A.5
Akita, G.Y.6
Kuriyama, T.7
Cheng, S.H.8
Gregory, R.J.9
Jiang, C.10
-
72
-
-
0344874751
-
Cell type-specific regulation of angiogenic growth factor gene expression and induction of angiogenesis in nonischemic tissue by a constitutively active form of hypoxia-inducible factor 1
-
Kelly BD, Hackett SF, Hirota K, Oshima Y, Cai Z, Berg-Dixon S, Rowan A, Yan Z, Campochiaro PA, Semenza GL: Cell type-specific regulation of angiogenic growth factor gene expression and induction of angiogenesis in nonischemic tissue by a constitutively active form of hypoxia-inducible factor 1. Circ Res 2003;93:1074-1081.
-
(2003)
Circ Res
, vol.93
, pp. 1074-1081
-
-
Kelly, B.D.1
Hackett, S.F.2
Hirota, K.3
Oshima, Y.4
Cai, Z.5
Berg-Dixon, S.6
Rowan, A.7
Yan, Z.8
Campochiaro, P.A.9
Semenza, G.L.10
-
73
-
-
0034671307
-
Hypoxia-inducible expression of tumor-associated carbonic anhydrases
-
Wykoff CC, Beasley NJ, Watson PH, Turner KJ, Pastorek J, Sibtain A, Wilson GD, Turley H, Talks KL, Maxwell PH, Pugh CW, Ratcliffe PJ, Harris AL: Hypoxia-inducible expression of tumor-associated carbonic anhydrases. Cancer Res 2000;60:7075-7083.
-
(2000)
Cancer Res
, vol.60
, pp. 7075-7083
-
-
Wykoff, C.C.1
Beasley, N.J.2
Watson, P.H.3
Turner, K.J.4
Pastorek, J.5
Sibtain, A.6
Wilson, G.D.7
Turley, H.8
Talks, K.L.9
Maxwell, P.H.10
Pugh, C.W.11
Ratcliffe, P.J.12
Harris, A.L.13
-
75
-
-
3142752573
-
Leukocyte adhesion during hypoxia is mediated by HIF-1-dependent induction of b2 integrin gene expression
-
USA
-
Kong T, Eltzschig HK, Karhausen J, Colgan SP, Shelley CS: Leukocyte adhesion during hypoxia is mediated by HIF-1-dependent induction of b2 integrin gene expression. Proc Natl Acad Sci USA 2004;101:10440-10445.
-
(2004)
Proc Natl Acad Sci
, vol.101
, pp. 10440-10445
-
-
Kong, T.1
Eltzschig, H.K.2
Karhausen, J.3
Colgan, S.P.4
Shelley, C.S.5
-
76
-
-
0141828145
-
Chemokine receptor CXCR4 downregulated by von Hippel-Lindau tumour suppressor pVHL
-
Staller P, Sulitjova A, Lisztwan J, Moch H, Oakeley EJ, Krek W: Chemokine receptor CXCR4 downregulated by von Hippel-Lindau tumour suppressor pVHL. Nature 2003;425:307-311.
-
(2003)
Nature
, vol.425
, pp. 307-311
-
-
Staller, P.1
Sulitjova, A.2
Lisztwan, J.3
Moch, H.4
Oakeley, E.J.5
Krek, W.6
-
77
-
-
0032900610
-
Functional role of p35srj, a novel p300/CBP binding protein, during transactivation by HIF-1
-
Battacharya S, Michels CL, Leung MK, Arany ZP, Kung AL, Livingston DM: Functional role of p35srj, a novel p300/CBP binding protein, during transactivation by HIF-1. Genes Dev 1999;13:64-75.
-
(1999)
Genes Dev
, vol.13
, pp. 64-75
-
-
Battacharya, S.1
Michels, C.L.2
Leung, M.K.3
Arany, Z.P.4
Kung, A.L.5
Livingston, D.M.6
-
78
-
-
0034647742
-
Role of hypoxia-inducible factor-1 in transcriptional activation of ceruloplasmin by iron deficiency
-
Mukhopadhyay CK, Mazumder B, Fox PL: Role of hypoxia-inducible factor-1 in transcriptional activation of ceruloplasmin by iron deficiency. J Biol Chem 2000;275:21048-21054.
-
(2000)
J Biol Chem
, vol.275
, pp. 21048-21054
-
-
Mukhopadhyay, C.K.1
Mazumder, B.2
Fox, P.L.3
-
79
-
-
0034640269
-
Hypoxic induction of prolyl 4-hydroxylase alpha (I) in cultured cells
-
Takahashi Y, Takahashi S, Shiga Y, Yoshimi T, Miura T: Hypoxic induction of prolyl 4-hydroxylase alpha (I) in cultured cells. J Biol Chem 2000;275:14139-14146.
-
(2000)
J Biol Chem
, vol.275
, pp. 14139-14146
-
-
Takahashi, Y.1
Takahashi, S.2
Shiga, Y.3
Yoshimi, T.4
Miura, T.5
-
80
-
-
8644229386
-
Hypoxic induction of Ctgf is directly mediated by Hif-1
-
Higgins DE, Biju MP, Akai Y, Wutz A, Johnson RS, Haase VH: Hypoxic induction of Ctgf is directly mediated by Hif-1. Am J Physiol 2004;287:F1223-F1232.
-
(2004)
Am J Physiol
, vol.287
-
-
Higgins, D.E.1
Biju, M.P.2
Akai, Y.3
Wutz, A.4
Johnson, R.S.5
Haase, V.H.6
-
81
-
-
0037214282
-
Hypoxia-inducible factor 1alpha is essential for cell cycle arrest during hypoxia
-
Goda N, Ryan HE, Khadivi B, McNulty W, Rickert RC, Johnson RS: Hypoxia-inducible factor 1alpha is essential for cell cycle arrest during hypoxia. Mol Cell Biol 2003;23:359-369.
-
(2003)
Mol Cell Biol
, vol.23
, pp. 359-369
-
-
Goda, N.1
Ryan, H.E.2
Khadivi, B.3
McNulty, W.4
Rickert, R.C.5
Johnson, R.S.6
-
82
-
-
0035499204
-
Hypoxia in cartilage: HIF-1alpha is essential for chondrocyte growth arrest and survival
-
Schipani E, Ryan HE, Didrickson S, Kobayashi T, Knight M, Johnson RS: Hypoxia in cartilage: HIF-1alpha is essential for chondrocyte growth arrest and survival. Genes Dev 2001;15:2865-2876.
-
(2001)
Genes Dev
, vol.15
, pp. 2865-2876
-
-
Schipani, E.1
Ryan, H.E.2
Didrickson, S.3
Kobayashi, T.4
Knight, M.5
Johnson, R.S.6
-
83
-
-
0037119456
-
Cyclooxygenase-2 and presenilin-1 gene expression induced by interleukin-1beta and amyloid beta 42 peptide is potentiated by hypoxia in primary human neural cells
-
Bazan NG, Lukiw WJ: Cyclooxygenase-2 and presenilin-1 gene expression induced by interleukin-1beta and amyloid beta 42 peptide is potentiated by hypoxia in primary human neural cells. J Biol Chem 2002;277:30359-30367.
-
(2002)
J Biol Chem
, vol.277
, pp. 30359-30367
-
-
Bazan, N.G.1
Lukiw, W.J.2
-
84
-
-
0037033095
-
Identification of functional hypoxia response elements in the promoter region of the DEC1 and DEC2 genes
-
Miyazaki K, Kawamoto T, Tanimoto K, Nishiyama M, Honda H, Kato Y: Identification of functional hypoxia response elements in the promoter region of the DEC1 and DEC2 genes. J Biol Chem 2002;277:47014-47021.
-
(2002)
J Biol Chem
, vol.277
, pp. 47014-47021
-
-
Miyazaki, K.1
Kawamoto, T.2
Tanimoto, K.3
Nishiyama, M.4
Honda, H.5
Kato, Y.6
-
85
-
-
0037113959
-
Endoglin expression is regulated by transcriptional cooperation between the hypoxia and transforming growth factor-beta pathways
-
Sanchez-Elsner T, Botella LM, Velasco B, Langa C, Bernabeu C: Endoglin expression is regulated by transcriptional cooperation between the hypoxia and transforming growth factor-beta pathways. J Biol Chem 2002;277:43799-43808.
-
(2002)
J Biol Chem
, vol.277
, pp. 43799-43808
-
-
Sanchez-Elsner, T.1
Botella, L.M.2
Velasco, B.3
Langa, C.4
Bernabeu, C.5
-
86
-
-
0032576971
-
Hypoxia regulates expression of the endothelin-1 gene through a proximal hypoxia-inducible factor-1 binding site on the antisense strand
-
Hu J, Discher DJ, Bishopric NH, Webster KA: Hypoxia regulates expression of the endothelin-1 gene through a proximal hypoxia-inducible factor-1 binding site on the antisense strand. Biochem Biophys Res Commun 1998;245:894-899.
-
(1998)
Biochem Biophys Res Commun
, vol.245
, pp. 894-899
-
-
Hu, J.1
Discher, D.J.2
Bishopric, N.H.3
Webster, K.A.4
-
87
-
-
0030460724
-
Hypoxia response elements in the aldolase A, enolase 1, and lactate dehydrogenase A gene promoters contain essential binding sites for hypoxia-inducible factor 1
-
Semenza GL, Jiang BH, Leung SW, Passantino R, Concordet JP, Maire P, Giallongo A: Hypoxia response elements in the aldolase A, enolase 1, and lactate dehydrogenase A gene promoters contain essential binding sites for hypoxia-inducible factor 1. J Biol Cem 1996;271:32529-32537.
-
(1996)
J Biol Cem
, vol.271
, pp. 32529-32537
-
-
Semenza, G.L.1
Jiang, B.H.2
Leung, S.W.3
Passantino, R.4
Concordet, J.P.5
Maire, P.6
Giallongo, A.7
-
88
-
-
0035941117
-
Hypoxia induces transcription factor ETS-1 via the activity of hypoxia-inducible factor-1
-
Oikawa M, Abe M, Kurosawa H, Hida W, Shirato K, Sato Y: Hypoxia induces transcription factor ETS-1 via the activity of hypoxia-inducible factor-1. Biochem Biophys Res Commun 2001;289:39-43.
-
(2001)
Biochem Biophys Res Commun
, vol.289
, pp. 39-43
-
-
Oikawa, M.1
Abe, M.2
Kurosawa, H.3
Hida, W.4
Shirato, K.5
Sato, Y.6
-
89
-
-
0035834598
-
Identification of genes differentially induced by hypoxia in pancreatic cancer cells
-
Yoon DY, Buchler P, Saarikoski ST, Hines OJ, Reber HA, Hankinson O: Identification of genes differentially induced by hypoxia in pancreatic cancer cells. Biochem Biophys Res Commun 2001;288:882-886.
-
(2001)
Biochem Biophys Res Commun
, vol.288
, pp. 882-886
-
-
Yoon, D.Y.1
Buchler, P.2
Saarikoski, S.T.3
Hines, O.J.4
Reber, H.A.5
Hankinson, O.6
-
90
-
-
0035937715
-
Regulation of glut-1 mRNA by hypoxia-inducible factor-1: Interaction between H-ras and hypoxia
-
Chen C, Pore N, Behrooz A, Imail-Beigi F, Maity A: Regulation of glut-1 mRNA by hypoxia-inducible factor-1: interaction between H-ras and hypoxia. J Biol Chem 2001;276:9519-9525.
-
(2001)
J Biol Chem
, vol.276
, pp. 9519-9525
-
-
Chen, C.1
Pore, N.2
Behrooz, A.3
Imail-Beigi, F.4
Maity, A.5
-
91
-
-
0032741858
-
Identification of an oxygen responsive enhancer element in the glyceraldehyde-3-phosphate dehydrogenase gene
-
Graven KK, Yu Q, Pan D, Roncarati JS, Farber HW: Identification of an oxygen responsive enhancer element in the glyceraldehyde-3-phosphate dehydrogenase gene. Biochim Biophys Acta 1999;1447:208-218.
-
(1999)
Biochim Biophys Acta
, vol.1447
, pp. 208-218
-
-
Graven, K.K.1
Yu, Q.2
Pan, D.3
Roncarati, J.S.4
Farber, H.W.5
-
92
-
-
0031041377
-
Hypoxia-inducible factor-1 mediates transcriptional activation of the heme oxygenase-1 gene in response to hypoxia
-
Lee PJ, Jiang BH, Chin BY, Iyer NV, Alam J, Semenza GL, Choi AM: Hypoxia-inducible factor-1 mediates transcriptional activation of the heme oxygenase-1 gene in response to hypoxia. J Biol Chem 1997;272:5375-5381.
-
(1997)
J Biol Chem
, vol.272
, pp. 5375-5381
-
-
Lee, P.J.1
Jiang, B.H.2
Chin, B.Y.3
Iyer, N.V.4
Alam, J.5
Semenza, G.L.6
Choi, A.M.7
-
93
-
-
0035900767
-
Glucose catabolism in cancer cells: Identification and characterization of a marked activation response of the type II hexokinase gene to hypoxic conditions
-
Mathupala SP, Rempel A, Pedersen PL: Glucose catabolism in cancer cells: identification and characterization of a marked activation response of the type II hexokinase gene to hypoxic conditions. J Biol Chem 2001;276:43407-43412.
-
(2001)
J Biol Chem
, vol.276
, pp. 43407-43412
-
-
Mathupala, S.P.1
Rempel, A.2
Pedersen, P.L.3
-
94
-
-
1942453828
-
Identification of the hypoxia-inducible factor 1 alpha-responsive HGTD-P gene as a mediator in the mitochondrial apoptotic pathway
-
Lee MJ, Kim JY, Suk K, Park JH: Identification of the hypoxia-inducible factor 1 alpha-responsive HGTD-P gene as a mediator in the mitochondrial apoptotic pathway. Mol Cell Biol 2004;24:3918-3927.
-
(2004)
Mol Cell Biol
, vol.24
, pp. 3918-3927
-
-
Lee, M.J.1
Kim, J.Y.2
Suk, K.3
Park, J.H.4
-
95
-
-
1542300383
-
The von-Hippel-Lindau/hypoxia inducible factor (HIF) pathway regulates the transcription of the HIF-proline hydroxylase genes in response to low oxygen
-
Del Peso L, Castellanos MC, Temes E, Martin-Pulg S, Cuevas Y, Olmos G, Landazuri MO: The von-Hippel-Lindau/hypoxia inducible factor (HIF) pathway regulates the transcription of the HIF-proline hydroxylase genes in response to low oxygen. J Biol Chem 2003;278:48690-48695.
-
(2003)
J Biol Chem
, vol.278
, pp. 48690-48695
-
-
Del Peso, L.1
Castellanos, M.C.2
Temes, E.3
Martin-Pulg, S.4
Cuevas, Y.5
Olmos, G.6
Landazuri, M.O.7
-
96
-
-
0030911247
-
Functional requirement of the hypoxia-responsive element in the activation of the inducible nitric oxide synthase promoter by the iron chelator desferrioxamine
-
Melillo G, Taylor LS, Brooks A, Musso T, Cox GW, Varesio L: Functional requirement of the hypoxia-responsive element in the activation of the inducible nitric oxide synthase promoter by the iron chelator desferrioxamine. J Biol Chem 1997;272:12236-12243.
-
(1997)
J Biol Chem
, vol.272
, pp. 12236-12243
-
-
Melillo, G.1
Taylor, L.S.2
Brooks, A.3
Musso, T.4
Cox, G.W.5
Varesio, L.6
-
97
-
-
4544361863
-
Induction of ID2 expression by hypoxia-inducible factor-1: A role in dedifferentiation of hypoxic neuroblastoma cells
-
Löfstedt T, Jogi A, Sigvardson M, Gradin K, Poellinger L, Pahlman S, Axelson H: Induction of ID2 expression by hypoxia-inducible factor-1: a role in dedifferentiation of hypoxic neuroblastoma cells. J Biol Chem 2004;279:39223-39231.
-
(2004)
J Biol Chem
, vol.279
, pp. 39223-39231
-
-
Löfstedt, T.1
Jogi, A.2
Sigvardson, M.3
Gradin, K.4
Poellinger, L.5
Pahlman, S.6
Axelson, H.7
-
98
-
-
0033566693
-
Reciprocal positive regulation of hypoxia-inducible factor-1 alpha and insulin-like growth factor2
-
Feldser D, Agani G, Iyer NV, Pak B, Ferreira G, Semenza GL: Reciprocal positive regulation of hypoxia-inducible factor-1 alpha and insulin-like growth factor2. Cancer Res 1999;59:3915-3918.
-
(1999)
Cancer Res
, vol.59
, pp. 3915-3918
-
-
Feldser, D.1
Agani, G.2
Iyer, N.V.3
Pak, B.4
Ferreira, G.5
Semenza, G.L.6
-
99
-
-
0035821249
-
Hypoxia-inducible factor 1-dependent induction of intestinal trefoil factor protects barrier function during hypoxia
-
Furuta GT, Turner JR, Taylor CT, Hershberg RM, Comerford K, Narravula S, Podolski DK, Colgan SP: Hypoxia-inducible factor 1-dependent induction of intestinal trefoil factor protects barrier function during hypoxia. J Exp Med 2001;193:1027-1034.
-
(2001)
J Exp Med
, vol.193
, pp. 1027-1034
-
-
Furuta, G.T.1
Turner, J.R.2
Taylor, C.T.3
Hershberg, R.M.4
Comerford, K.5
Narravula, S.6
Podolski, D.K.7
Colgan, S.P.8
-
100
-
-
0037044813
-
Hypoxia-inducible factor 1 transactivates the human leptin gene promoter
-
Grosfeld A, Andre J, Hauguel-De Mouzon S, Berra E, Pouyssegur J, Guerre-Millo M: Hypoxia-inducible factor 1 transactivates the human leptin gene promoter. J Biol Chem 2002;277:42953-42957.
-
(2002)
J Biol Chem
, vol.277
, pp. 42953-42957
-
-
Grosfeld, A.1
Andre, J.2
Hauguel-De Mouzon, S.3
Berra, E.4
Pouyssegur, J.5
Guerre-Millo, M.6
-
101
-
-
0037096732
-
Hypoxia-inducible factor-1-dependent regulation of the multidrug resistance (MDR1) gene
-
Comerford KM, Wallace JT, Karhausen J, Louis NA, Montalto MC, Colgan SP: Hypoxia-inducible factor-1-dependent regulation of the multidrug resistance (MDR1) gene. Cancer Res 2002;62:3387-3394.
-
(2002)
Cancer Res
, vol.62
, pp. 3387-3394
-
-
Comerford, K.M.1
Wallace, J.T.2
Karhausen, J.3
Louis, N.A.4
Montalto, M.C.5
Colgan, S.P.6
-
102
-
-
0034255036
-
Expression of the gene encoding the proapoptotic Nip3 protein is induced by hypoxia
-
USA
-
Bruick RK: Expression of the gene encoding the proapoptotic Nip3 protein is induced by hypoxia. Proc Natl Acad Sci USA 2000;97: 9082-9087.
-
(2000)
Proc Natl Acad Sci
, vol.97
, pp. 9082-9087
-
-
Bruick, R.K.1
-
103
-
-
0035884701
-
HIF-1-dependent regulation of hypoxic induction of the cell death factors BNIP3 and NIX in human tumors
-
Sowter HM, Ratcliffe PJ, Watson P, Greenberg AH, Harris AL: HIF-1-dependent regulation of hypoxic induction of the cell death factors BNIP3 and NIX in human tumors. Cancer Res 2001;61:6669-6673.
-
(2001)
Cancer Res
, vol.61
, pp. 6669-6673
-
-
Sowter, H.M.1
Ratcliffe, P.J.2
Watson, P.3
Greenberg, A.H.4
Harris, A.L.5
-
104
-
-
85047685683
-
Ecto-5′-nucleotidase (CD73) regulation by hypoxia-inducible factor-1 mediates permeability changes in intestinal epithelia
-
Synnestvedt K, Furuta GT, Comerford KM, Louis N, Karhausen J, Eltzschig HK, Hansen KR, Thompson LF, Colgan SP: Ecto-5′-nucleotidase (CD73) regulation by hypoxia-inducible factor-1 mediates permeability changes in intestinal epithelia. J Clin Invest 2002;110:993-1002.
-
(2002)
J Clin Invest
, vol.110
, pp. 993-1002
-
-
Synnestvedt, K.1
Furuta, G.T.2
Comerford, K.M.3
Louis, N.4
Karhausen, J.5
Eltzschig, H.K.6
Hansen, K.R.7
Thompson, L.F.8
Colgan, S.P.9
-
105
-
-
0035877163
-
Hypoxia-inducible factor 1-mediated inhibition of peroxisome proliferator-activated receptor alpha expression during hypoxia
-
Narravula S, Colgan SP: Hypoxia-inducible factor 1-mediated inhibition of peroxisome proliferator-activated receptor alpha expression during hypoxia. J Immunol 2001;166:7543-7548.
-
(2001)
J Immunol
, vol.166
, pp. 7543-7548
-
-
Narravula, S.1
Colgan, S.P.2
-
106
-
-
33644990317
-
-
Erratum
-
Erratum in J Immunol 2002;68:3113.
-
(2002)
J Immunol
, vol.68
, pp. 3113
-
-
-
107
-
-
0036660804
-
Hypoxia up-regulates expression of peroxisome proliferator-activated receptor gamma angiopoietin-related gene (PGAR) in cardiomyocytes: Role of hypoxia inducible factor 1alpha
-
Belanger AJ, Lu H, Date T, Liu LX, Vincent KA, Akita GY, Cheng SH, Gregory RJ, Jiang C: Hypoxia up-regulates expression of peroxisome proliferator-activated receptor gamma angiopoietin-related gene (PGAR) in cardiomyocytes: role of hypoxia inducible factor 1alpha. J Mol Cell Cardiol 2002;34:765-774.
-
(2002)
J Mol Cell Cardiol
, vol.34
, pp. 765-774
-
-
Belanger, A.J.1
Lu, H.2
Date, T.3
Liu, L.X.4
Vincent, K.A.5
Akita, G.Y.6
Cheng, S.H.7
Gregory, R.J.8
Jiang, C.9
-
108
-
-
0037155247
-
Hypoxia-inducible factor-1-mediated expression of the 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase-3 (PFKFB3) gene. Its possible role in the Warburg effect
-
Minchenko A, Leshchinski I, Opentanova I, Sang N, Srinivas V, Armstead V, Caro J: Hypoxia-inducible factor-1-mediated expression of the 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase-3 (PFKFB3) gene. Its possible role in the Warburg effect. J Biol Chem 2002;277:6183-6187.
-
(2002)
J Biol Chem
, vol.277
, pp. 6183-6187
-
-
Minchenko, A.1
Leshchinski, I.2
Opentanova, I.3
Sang, N.4
Srinivas, V.5
Armstead, V.6
Caro, J.7
-
109
-
-
0032795850
-
Induction of the plasminogen activator inhibitor-1 gene expression by mild hypoxia via a hypoxia response element binding the hypoxia-inducible factor-1 in rat hepatocytes
-
Kietzmann T, Roth U, Jungermann K: Induction of the plasminogen activator inhibitor-1 gene expression by mild hypoxia via a hypoxia response element binding the hypoxia-inducible factor-1 in rat hepatocytes. Blood 1999;94:4177-4185.
-
(1999)
Blood
, vol.94
, pp. 4177-4185
-
-
Kietzmann, T.1
Roth, U.2
Jungermann, K.3
-
110
-
-
0035931493
-
Presenilin-2 (PS2) expression up-regulation in a model of retinopathy of prematurity and pathoangiogenesis
-
Lukiw WJ, Gordon WC, Rogaev EI, Thompson H, Bazan NG: Presenilin-2 (PS2) expression up-regulation in a model of retinopathy of prematurity and pathoangiogenesis. Neuroreport 2001;12:53-57.
-
(2001)
Neuroreport
, vol.12
, pp. 53-57
-
-
Lukiw, W.J.1
Gordon, W.C.2
Rogaev, E.I.3
Thompson, H.4
Bazan, N.G.5
-
111
-
-
0035974803
-
Identification of an angiogenic mitogen selective for endocrine gland endothelium
-
LeCouter J, Kowalski J, Foster J, Hass P, Zhang Z, Dillard-Telm L, Frantz G, Rangell L, DeGuzman L, Keller GA, Peale F, Gurney A, Hillan KJ, Ferrara N: Identification of an angiogenic mitogen selective for endocrine gland endothelium. Nature 2001;412:877-884.
-
(2001)
Nature
, vol.412
, pp. 877-884
-
-
LeCouter, J.1
Kowalski, J.2
Foster, J.3
Hass, P.4
Zhang, Z.5
Dillard-Telm, L.6
Frantz, G.7
Rangell, L.8
DeGuzman, L.9
Keller, G.A.10
Peale, F.11
Gurney, A.12
Hillan, K.J.13
Ferrara, N.14
-
112
-
-
0036118562
-
Identification of a novel hypoxia-inducible factor 1 -responsive gene, RTP801, involved in apoptosis
-
Shoshani T, Faerman A, Mett I, Zelin E, Tenne T, Gorodin S, Moshel Y, Elbaz S, Budanov A, Chajut A, Kalinski H, Kamer I, Rozen A, Mor O, Keshet E, Leshkowitz D, Einat P, Skaliter R, Feinstein E: Identification of a novel hypoxia-inducible factor 1 -responsive gene, RTP801, involved in apoptosis. Mol Cell Biol 2002;22:2283-2293.
-
(2002)
Mol Cell Biol
, vol.22
, pp. 2283-2293
-
-
Shoshani, T.1
Faerman, A.2
Mett, I.3
Zelin, E.4
Tenne, T.5
Gorodin, S.6
Moshel, Y.7
Elbaz, S.8
Budanov, A.9
Chajut, A.10
Kalinski, H.11
Kamer, I.12
Rozen, A.13
Mor, O.14
Keshet, E.15
Leshkowitz, D.16
Einat, P.17
Skaliter, R.18
Feinstein, E.19
-
113
-
-
9444283789
-
The gene encoding human retinoic acid-receptor-related orphan receptor alpha is a target for hypoxia-inducible factor 1
-
Chauvet C, Bois-Joyeux B, Berra E, Pouyssegur J, Danan JL: The gene encoding human retinoic acid-receptor-related orphan receptor alpha is a target for hypoxia-inducible factor 1. Biochem J 2004;384:79-85.
-
(2004)
Biochem J
, vol.384
, pp. 79-85
-
-
Chauvet, C.1
Bois-Joyeux, B.2
Berra, E.3
Pouyssegur, J.4
Danan, J.L.5
-
114
-
-
0141890293
-
The role of HIF-1 alpha in transcriptional regulation of the proximal tubular epithelial cell response to hypoxia
-
Leonard MO, Cottel DC, Godson C, Brady HR, Taylor CT: The role of HIF-1 alpha in transcriptional regulation of the proximal tubular epithelial cell response to hypoxia. J Biol Chem 2003;278:40296-40304.
-
(2003)
J Biol Chem
, vol.278
, pp. 40296-40304
-
-
Leonard, M.O.1
Cottel, D.C.2
Godson, C.3
Brady, H.R.4
Taylor, C.T.5
-
115
-
-
4043184065
-
Progenitor cell trafficking is regulated by hypoxic gradients through HIF-1 induction of SDF-1
-
Ceradini DJ, Kulkarni AR, Callaghan MJ, Tepper OM, Bastidas N, Kleinman ME, Capla JM, Galiano RD, Levine JP, Gurtner GC: Progenitor cell trafficking is regulated by hypoxic gradients through HIF-1 induction of SDF-1. Nat Med 2004;10:858-864.
-
(2004)
Nat Med
, vol.10
, pp. 858-864
-
-
Ceradini, D.J.1
Kulkarni, A.R.2
Callaghan, M.J.3
Tepper, O.M.4
Bastidas, N.5
Kleinman, M.E.6
Capla, J.M.7
Galiano, R.D.8
Levine, J.P.9
Gurtner, G.C.10
-
116
-
-
0030792094
-
Oxygen-regulated transferrin expression is mediated by hypoxia-inducible factor-1
-
Rolfs A, Kvietikova I, Gassmann M, Wenger RH: Oxygen-regulated transferrin expression is mediated by hypoxia-inducible factor-1. J Biol Chem 1997;272:20055-20062.
-
(1997)
J Biol Chem
, vol.272
, pp. 20055-20062
-
-
Rolfs, A.1
Kvietikova, I.2
Gassmann, M.3
Wenger, R.H.4
-
117
-
-
0000655498
-
Identification of a hypoxia response element in the transferrin receptor gene
-
Lok CN, Ponka P: Identification of a hypoxia response element in the transferrin receptor gene. J Biol Chem 1999;274:24147-24152.
-
(1999)
J Biol Chem
, vol.274
, pp. 24147-24152
-
-
Lok, C.N.1
Ponka, P.2
-
118
-
-
0036511366
-
Physiologically low oxygen concentrations in fetal skin regulate hypoxia-inducible factor 1 and transforming growth factor-beta3
-
Scheid A, Wenger RH, Schaffer L, Camenisch I, Distler O, Ferenc A, Cristina H, Ryan HE, Johnson RS, Wagner KF, Stauffer UG, Bauer C, Gassmann M, Meuli M: Physiologically low oxygen concentrations in fetal skin regulate hypoxia-inducible factor 1 and transforming growth factor-beta3. FASEB J 2002;16:411-413.
-
(2002)
FASEB J
, vol.16
, pp. 411-413
-
-
Scheid, A.1
Wenger, R.H.2
Schaffer, L.3
Camenisch, I.4
Distler, O.5
Ferenc, A.6
Cristina, H.7
Ryan, H.E.8
Johnson, R.S.9
Wagner, K.F.10
Stauffer, U.G.11
Bauer, C.12
Gassmann, M.13
Meuli, M.14
-
119
-
-
2442430224
-
Hypoxia up-regulates triosephosphate isomerase expression via a HIF-dependent pathway
-
Gess B, Hofbauer KH, Deutzmann R, Kurtz A: Hypoxia up-regulates triosephosphate isomerase expression via a HIF-dependent pathway. Pfluegers Arch 2004;448:175-180.
-
(2004)
Pfluegers Arch
, vol.448
, pp. 175-180
-
-
Gess, B.1
Hofbauer, K.H.2
Deutzmann, R.3
Kurtz, A.4
-
120
-
-
0028859483
-
2-responsive sequences on the tyrosine hydroxylase gene
-
2-responsive sequences on the tyrosine hydroxylase gene. J Biol Chem 1995;270:23774-23779.
-
(1995)
J Biol Chem
, vol.270
, pp. 23774-23779
-
-
Norris, M.L.1
Millhom, D.E.2
-
121
-
-
0029095371
-
Anoxic induction of sarcoma virus-related VL30 retrotransposon is mediated by cis-acting element which binds hypoxia-inducible factor 1 and an anoxia-inducible factor
-
Estes SD, Stoler DL, Anderson GR: Anoxic induction of sarcoma virus-related VL30 retrotransposon is mediated by cis-acting element which binds hypoxia-inducible factor 1 and an anoxia-inducible factor. J Virol 1995;69:6335-6341.
-
(1995)
J Virol
, vol.69
, pp. 6335-6341
-
-
Estes, S.D.1
Stoler, D.L.2
Anderson, G.R.3
-
122
-
-
0029103274
-
Hypoxia regulates vascular endothelial growth factor gene expression in endothelial cells. Identification of a 5′ enhancer
-
Liu Y, Cox SR, Morita T, Kourembanas S: Hypoxia regulates vascular endothelial growth factor gene expression in endothelial cells. Identification of a 5′ enhancer. Circ Res 1995;77:638-643.
-
(1995)
Circ Res
, vol.77
, pp. 638-643
-
-
Liu, Y.1
Cox, S.R.2
Morita, T.3
Kourembanas, S.4
-
123
-
-
0030751493
-
Differential transcriptional regulation of the two vascular endothelial growth factor receptor genes. Flt-1, but not Flk-1/KDR, is upregulated by hypoxia
-
Gerber HP, Condorelli F, Park J, Ferrara N: Differential transcriptional regulation of the two vascular endothelial growth factor receptor genes. Flt-1, but not Flk-1/KDR, is upregulated by hypoxia. J Biol Chem 1997;272:23659-23667.
-
(1997)
J Biol Chem
, vol.272
, pp. 23659-23667
-
-
Gerber, H.P.1
Condorelli, F.2
Park, J.3
Ferrara, N.4
-
124
-
-
0038265455
-
Oxygen-regulated expression of the Wilms' tumor suppressor Wt1 involves hypoxia-inducible factor-1 (HIF-1)
-
Wagner KD, Wagner N, Wellmann S, Schley G, Bondke A, Theres H, Scholz H: Oxygen-regulated expression of the Wilms' tumor suppressor Wt1 involves hypoxia-inducible factor-1 (HIF-1). FASEB J 2003;17:1364-1366.
-
(2003)
FASEB J
, vol.17
, pp. 1364-1366
-
-
Wagner, K.D.1
Wagner, N.2
Wellmann, S.3
Schley, G.4
Bondke, A.5
Theres, H.6
Scholz, H.7
-
125
-
-
0035354579
-
Pleiotropic and tissue-specific expression of erythropoietin
-
Sasaki R, Masuda S, Nagao M: Pleiotropic and tissue-specific expression of erythropoietin. News Physiol Sci 2001;16:110-113.
-
(2001)
News Physiol Sci
, vol.16
, pp. 110-113
-
-
Sasaki, R.1
Masuda, S.2
Nagao, M.3
-
126
-
-
19444372033
-
Erythropoietin mimics ischemic preconditioning
-
Baker JE: Erythropoietin mimics ischemic preconditioning. Vasc Pharmacol 2005;42: 233-241.
-
(2005)
Vasc Pharmacol
, vol.42
, pp. 233-241
-
-
Baker, J.E.1
-
128
-
-
0034788622
-
Hypoxia and hypoxia-inducible factor modulated gene expression in brain: Involvement in neuroprotection and cell death
-
Kietzmann T, Knabe W, Schmidt-Kastner R: Hypoxia and hypoxia-inducible factor modulated gene expression in brain: involvement in neuroprotection and cell death. Eur Arch Psychiatry Clin Neurosci 2001;251:170-178.
-
(2001)
Eur Arch Psychiatry Clin Neurosci
, vol.251
, pp. 170-178
-
-
Kietzmann, T.1
Knabe, W.2
Schmidt-Kastner, R.3
-
129
-
-
11244333356
-
New avenues of exploration for erythropoietin
-
Maiese K, Li F, Chong ZZ: New avenues of exploration for erythropoietin. JAMA 2005;293:90-95.
-
(2005)
JAMA
, vol.293
, pp. 90-95
-
-
Maiese, K.1
Li, F.2
Chong, Z.Z.3
-
130
-
-
4344626952
-
Low-dose therapy with the long-acting erythropoietin analogue darbepoetin alpha persistently activates endothelial Akt and attenuates progressive organ failure
-
Bahlmann FH, Song R, Boehm SM, Mengel M, von Wasielewski R, Lindschau C, Kirsch T, de Groot K, Laudeley R, Niemczyk E, Guler F, Menne J, Haller H, Fliser D: Low-dose therapy with the long-acting erythropoietin analogue darbepoetin alpha persistently activates endothelial Akt and attenuates progressive organ failure. Circulation 2004;110:1006-1012.
-
(2004)
Circulation
, vol.110
, pp. 1006-1012
-
-
Bahlmann, F.H.1
Song, R.2
Boehm, S.M.3
Mengel, M.4
Von Wasielewski, R.5
Lindschau, C.6
Kirsch, T.7
De Groot, K.8
Laudeley, R.9
Niemczyk, E.10
Guler, F.11
Menne, J.12
Haller, H.13
Fliser, D.14
-
131
-
-
23744443462
-
HIF-1 activation attenuates postischemic myocardial injury: Role for heme oxygenase-1 in mod3 ulating microvascular chemokine generation
-
Ockaili R, Natarajan R, Salloum F, Fisher BJ, Jones D, Fowler III AA, Kukreja RC: HIF-1 activation attenuates postischemic myocardial injury: role for heme oxygenase-1 in mod3 ulating microvascular chemokine generation. Am J Physiol 2005;289:H542-H548.
-
(2005)
Am J Physiol
, vol.289
-
-
Ockaili, R.1
Natarajan, R.2
Salloum, F.3
Fisher, B.J.4
Jones, D.5
Fowler III, A.A.6
Kukreja, R.C.7
-
132
-
-
0034529932
-
Heme oxygenase: Colors of defense against cellular stress
-
Otterbein LE, Choi AMK: Heme oxygenase: colors of defense against cellular stress. Am J Physiol 2000;279:L1029-L1037.
-
(2000)
Am J Physiol
, vol.279
-
-
Otterbein, L.E.1
Choi, A.M.K.2
-
133
-
-
9344262366
-
Cobalt chloride induces delayed cardiac preconditioning in mice through selective activation of HIF-1alpha and AP-1 and iNOS signaling
-
Xi L, Taller M, Yin C, Salloum F, Kukreja RC: Cobalt chloride induces delayed cardiac preconditioning in mice through selective activation of HIF-1alpha and AP-1 and iNOS signaling. Am J Physiol 2004;287:H2369-H2375.
-
(2004)
Am J Physiol
, vol.287
-
-
Xi, L.1
Taller, M.2
Yin, C.3
Salloum, F.4
Kukreja, R.C.5
-
134
-
-
0345304232
-
Reactive oxygen species and molecular regulation of renal oxygenation
-
Zou AP, Cowley AW Jr: Reactive oxygen species and molecular regulation of renal oxygenation. Acta Physiol Scand 2003;179:233-241.
-
(2003)
Acta Physiol Scand
, vol.179
, pp. 233-241
-
-
Zou, A.P.1
Cowley Jr., A.W.2
-
135
-
-
0035159670
-
HIF-1 is expressed in normoxic tissue and displays an organ-specific regulation under systemic hypoxia
-
Stroka D. Burkhard T, Desbaillets I, Wenger RH, Neil DAH, Bauer C, Gassmann M, Candinas D: HIF-1 is expressed in normoxic tissue and displays an organ-specific regulation under systemic hypoxia. FASEB J 2001;15:2445-2453.
-
(2001)
FASEB J
, vol.15
, pp. 2445-2453
-
-
Stroka, D.1
Burkhard, T.2
Desbaillets, I.3
Wenger, R.H.4
Neil, D.A.H.5
Bauer, C.6
Gassmann, M.7
Candinas, D.8
-
136
-
-
0347711871
-
Oxygen-dependent expression of hypoxia-inducible factor-1a in renal medullary cells of rats
-
Zou AP, Yang ZZ, Li PL, Cowley AW Jr: Oxygen-dependent expression of hypoxia-inducible factor-1a in renal medullary cells of rats. Physiol Genom 2001;6:159-168.
-
(2001)
Physiol Genom
, vol.6
, pp. 159-168
-
-
Zou, A.P.1
Yang, Z.Z.2
Li, P.L.3
Cowley Jr., A.W.4
-
137
-
-
18444380862
-
Expression of hypoxia-inducible factor-1 alpha and -2alpha in hypoxic and ischemic rat kidneys
-
Rosenberger C, Mandriota S, Juergensen JS, Wiesener MS, Hoerstrup JH, Frei U, Ratcliffe PJ, Maxwell PH, Bachmann S, Eckardt KU: Expression of hypoxia-inducible factor-1 alpha and -2alpha in hypoxic and ischemic rat kidneys. J Am Soc Nephrol 2002;13:1721-1732.
-
(2002)
J Am Soc Nephrol
, vol.13
, pp. 1721-1732
-
-
Rosenberger, C.1
Mandriota, S.2
Juergensen, J.S.3
Wiesener, M.S.4
Hoerstrup, J.H.5
Frei, U.6
Ratcliffe, P.J.7
Maxwell, P.H.8
Bachmann, S.9
Eckardt, K.U.10
-
138
-
-
0042932770
-
Cellular responses to hypoxia after renal segmental infarction
-
Rosenberger C, Griethe W, Gruber G, Wiesener MS, Frei U, Bachmann S, Eckardt KU: Cellular responses to hypoxia after renal segmental infarction. Kidney Int 2003;64:874-886.
-
(2003)
Kidney Int
, vol.64
, pp. 874-886
-
-
Rosenberger, C.1
Griethe, W.2
Gruber, G.3
Wiesener, M.S.4
Frei, U.5
Bachmann, S.6
Eckardt, K.U.7
-
139
-
-
0345707657
-
Peritubular capillary loss after mouse acute nephrotoxicity correlates with down-regulation of vascular endothelial growth factor-a and hypoxia-inducible factor-1a
-
Yuan HAT, Li XZ, Pitera JE, Long DA, Woolf AS: Peritubular capillary loss after mouse acute nephrotoxicity correlates with down-regulation of vascular endothelial growth factor-a and hypoxia-inducible factor-1a. Am J Pathol 2003:163:2289-2301.
-
(2003)
Am J Pathol
, vol.163
, pp. 2289-2301
-
-
Yuan, H.A.T.1
Li, X.Z.2
Pitera, J.E.3
Long, D.A.4
Woolf, A.S.5
-
140
-
-
1942506587
-
Evidence of tubular hypoxia in the early phase in the remnant kidney model
-
Monotham K, Tanaka T, Matsumoto M, Ohse T, Miyata T, Inagi R, Kurokawa K, Fujita T, Nangaku M: Evidence of tubular hypoxia in the early phase in the remnant kidney model. J Am Soc Nephrol 2004;15:1277-1288.
-
(2004)
J Am Soc Nephrol
, vol.15
, pp. 1277-1288
-
-
Monotham, K.1
Tanaka, T.2
Matsumoto, M.3
Ohse, T.4
Miyata, T.5
Inagi, R.6
Kurokawa, K.7
Fujita, T.8
Nangaku, M.9
-
141
-
-
11144337355
-
Mechanism of hypertensive nephropathy in the Dahl/Rapp rat: A primary disorder of vascular smooth muscle
-
Wang PX, Sanders PW: Mechanism of hypertensive nephropathy in the Dahl/Rapp rat: a primary disorder of vascular smooth muscle. Am J Physiol 2004;288:236-242.
-
(2004)
Am J Physiol
, vol.288
, pp. 236-242
-
-
Wang, P.X.1
Sanders, P.W.2
-
142
-
-
19944432424
-
Up-regulation of HIF in experimental acute renal failure: Evidence for a protective transcriptional response to hypoxia
-
Rosenberger C, Heyman SN, Rosen S, Shina A, Goldfarb M, Griethe W, Frei U, Reinke P, Bachmann S, Eckardt KU: Up-regulation of HIF in experimental acute renal failure: evidence for a protective transcriptional response to hypoxia. Kidney Int 2005;67:531-542.
-
(2005)
Kidney Int
, vol.67
, pp. 531-542
-
-
Rosenberger, C.1
Heyman, S.N.2
Rosen, S.3
Shina, A.4
Goldfarb, M.5
Griethe, W.6
Frei, U.7
Reinke, P.8
Bachmann, S.9
Eckardt, K.U.10
-
143
-
-
20144386806
-
A biologic role of HIF-1 in the renal medulla
-
Monotham K, Tanaka T, Ohse T, Kojima I, Miyata T, Inagi R, Tanaka H, Sassa R, Fujita T, Nangaku M: A biologic role of HIF-1 in the renal medulla. J Am Soc Nephrol 2005;67:1428-1439.
-
(2005)
J Am Soc Nephrol
, vol.67
, pp. 1428-1439
-
-
Monotham, K.1
Tanaka, T.2
Ohse, T.3
Kojima, I.4
Miyata, T.5
Inagi, R.6
Tanaka, H.7
Sassa, R.8
Fujita, T.9
Nangaku, M.10
-
144
-
-
16644392596
-
HIF-1a expression follows microvascular loss in advanced murine adriamycin nephrosis
-
Kairaitis LK, Wang Y, Gassmann M, Tay YC, Harris DCH: HIF-1a expression follows microvascular loss in advanced murine adriamycin nephrosis. Am J Physiol 2005;288: F198-F206.
-
(2005)
Am J Physiol
, vol.288
-
-
Kairaitis, L.K.1
Wang, Y.2
Gassmann, M.3
Tay, Y.C.4
Harris, D.C.H.5
-
145
-
-
20944446740
-
Hypoxia-inducible factor-1α is involved in the attenuation of experimentally induced rat glomerulonephritis
-
Kudo Y, Kakinuma Y, Mori Y, Morimoto N, Karashima T, Furihata M, Sato T, Shuin T, Sugiura T: Hypoxia-inducible factor-1α is involved in the attenuation of experimentally induced rat glomerulonephritis. Exp Nephrol 2005;100:e95-e103.
-
(2005)
Exp Nephrol
, vol.100
-
-
Kudo, Y.1
Kakinuma, Y.2
Mori, Y.3
Morimoto, N.4
Karashima, T.5
Furihata, M.6
Sato, T.7
Shuin, T.8
Sugiura, T.9
-
146
-
-
0027410945
-
Co-localization of erythropoietin mRNA and ecto-5′-nucleotidase immunoreactivity in peritubular cells of rat renal cortex indicates that fibroblasts produce erythropoietin
-
Bachmann S, Le Hir M, Eckardt KU: Co-localization of erythropoietin mRNA and ecto-5′-nucleotidase immunoreactivity in peritubular cells of rat renal cortex indicates that fibroblasts produce erythropoietin. J Histochem Cytochem 1993;41:335-341.
-
(1993)
J Histochem Cytochem
, vol.41
, pp. 335-341
-
-
Bachmann, S.1
Le Hir, M.2
Eckardt, K.U.3
|