메뉴 건너뛰기




Volumn 293, Issue 1, 2005, Pages 90-95

New avenues of exploration for erythropoietin

Author keywords

[No Author keywords available]

Indexed keywords

ERYTHROPOIETIN; NOVEL ERYTHROPOIESIS STIMULATING PROTEIN;

EID: 11244333356     PISSN: 00987484     EISSN: None     Source Type: Journal    
DOI: 10.1001/jama.293.1.90     Document Type: Review
Times cited : (485)

References (50)
  • 1
    • 0030699055 scopus 로고    scopus 로고
    • Effect of active oxygen radicals on protein and carbohydrate moieties of recombinant human erythropoietin
    • Uchida E, Morimoto K, Kawasaki N, Izaki Y, Abdu Said A, Hayakawa T. Effect of active oxygen radicals on protein and carbohydrate moieties of recombinant human erythropoietin. Free Radic Res. 1997;27:311-323.
    • (1997) Free Radic Res , vol.27 , pp. 311-323
    • Uchida, E.1    Morimoto, K.2    Kawasaki, N.3    Izaki, Y.4    Abdu Said, A.5    Hayakawa, T.6
  • 2
    • 0036244550 scopus 로고    scopus 로고
    • Hematopoietic factor erythropoietin fosters neuroprotection through novel signal transduction cascades
    • Chong ZZ, Kang JQ, Maiese K. Hematopoietic factor erythropoietin fosters neuroprotection through novel signal transduction cascades. J Cereb Blood Flow Metab. 2002;22:503-514.
    • (2002) J Cereb Blood Flow Metab , vol.22 , pp. 503-514
    • Chong, Z.Z.1    Kang, J.Q.2    Maiese, K.3
  • 3
    • 0036972737 scopus 로고    scopus 로고
    • Angiogenesis and plasticity: Role of erythropoietin in vascular systems
    • Chong ZZ, Kang JQ, Maiese K. Angiogenesis and plasticity: role of erythropoietin in vascular systems. J Hematother Stem Cell Res. 2002;11:863-871.
    • (2002) J Hematother Stem Cell Res , vol.11 , pp. 863-871
    • Chong, Z.Z.1    Kang, J.Q.2    Maiese, K.3
  • 4
    • 3042743888 scopus 로고    scopus 로고
    • Erythropoietin as a novel neuroprotectant
    • Gene S, Koroglu TF, Gene K. Erythropoietin as a novel neuroprotectant. Res Neurol Neurosci. 2004;22: 105-119.
    • (2004) Res Neurol Neurosci , vol.22 , pp. 105-119
    • Gene, S.1    Koroglu, T.F.2    Gene, K.3
  • 5
    • 0028260228 scopus 로고
    • Erythropoietin receptor mRNA expression in human endothelial cells
    • Anagnostou A, Liu Z, Steiner M, et al. Erythropoietin receptor mRNA expression in human endothelial cells. Proc Natl Acad Sci U S A 1994;91:3974-3978.
    • (1994) Proc Natl Acad Sci U S A , vol.91 , pp. 3974-3978
    • Anagnostou, A.1    Liu, Z.2    Steiner, M.3
  • 6
    • 0033561341 scopus 로고    scopus 로고
    • Human erythropoietin induces a pro-angiogenic phenotype in cultured endothelial cells and stimulates neovascularization in vivo
    • Ribatti D, Presta M, Vacca A, et al. Human erythropoietin induces a pro-angiogenic phenotype in cultured endothelial cells and stimulates neovascularization in vivo. Blood. 1999;93:2627-2636.
    • (1999) Blood , vol.93 , pp. 2627-2636
    • Ribatti, D.1    Presta, M.2    Vacca, A.3
  • 7
    • 1642286962 scopus 로고    scopus 로고
    • Modulating the hypoxia-inducible factor signaling pathway: Applications from cardiovascular disease to cancer
    • Hewitson KS, McNeill LA, Schofield CJ. Modulating the hypoxia-inducible factor signaling pathway: applications from cardiovascular disease to cancer. Curr Pharm Des. 2004;10:821-833.
    • (2004) Curr Pharm Des , vol.10 , pp. 821-833
    • Hewitson, K.S.1    McNeill, L.A.2    Schofield, C.J.3
  • 8
    • 11244266064 scopus 로고    scopus 로고
    • Regulation of endothelial cell death and its role in angiogenesis and vascular regression
    • Sakamaki K. Regulation of endothelial cell death and its role in angiogenesis and vascular regression. Curr Neurovasc Res. 2004;1:305-315.
    • (2004) Curr Neurovasc Res , vol.1 , pp. 305-315
    • Sakamaki, K.1
  • 9
    • 3042819409 scopus 로고    scopus 로고
    • Insights into oxidative stress and potential novel therapeutic targets for Alzheimer disease
    • Maiese K, Chong ZZ. Insights into oxidative stress and potential novel therapeutic targets for Alzheimer disease. Restor Neurol Neurosci. 2004;22:87-104.
    • (2004) Restor Neurol Neurosci , vol.22 , pp. 87-104
    • Maiese, K.1    Chong, Z.Z.2
  • 10
    • 2442587705 scopus 로고    scopus 로고
    • Phosphatidylinositol-3-kinase signaling is required for erythropoietin-mediated acute protection against myocardial ischemia/ reperfusion injury
    • Cai Z, Semenza GL. Phosphatidylinositol-3-kinase signaling is required for erythropoietin-mediated acute protection against myocardial ischemia/ reperfusion injury. Circulation. 2004;109:2050-2053.
    • (2004) Circulation , vol.109 , pp. 2050-2053
    • Cai, Z.1    Semenza, G.L.2
  • 11
    • 0036064271 scopus 로고    scopus 로고
    • HIF-1-induced erythropoietin in the hypoxic retina protects against light-induced retinal degeneration
    • Grimm C, Wenzel A, Groszer M, et al. HIF-1-induced erythropoietin in the hypoxic retina protects against light-induced retinal degeneration. Nat Med. 2002;8:718-724.
    • (2002) Nat Med , vol.8 , pp. 718-724
    • Grimm, C.1    Wenzel, A.2    Groszer, M.3
  • 12
    • 0037365196 scopus 로고    scopus 로고
    • Erythropoietin fosters both intrinsic and extrinsic neuronal protection through modulation of microglia, Akt1, Bad, and caspase-mediated pathways
    • Chong ZZ, Kang JQ, Maiese K. Erythropoietin fosters both intrinsic and extrinsic neuronal protection through modulation of microglia, Akt1, Bad, and caspase-mediated pathways. Br J Pharmacol. 2003;138:1107-1118.
    • (2003) Br J Pharmacol , vol.138 , pp. 1107-1118
    • Chong, Z.Z.1    Kang, J.Q.2    Maiese, K.3
  • 13
    • 0037369477 scopus 로고    scopus 로고
    • Erythropoietin prevents early and late neuronal demise through modulation of Akt1 and induction of caspase 1, 3, and 8
    • Chong ZZ, Lin SH, Kang JQ, Maiese K. Erythropoietin prevents early and late neuronal demise through modulation of Akt1 and induction of caspase 1, 3, and 8. J Neurosci Res. 2003;71:659-669.
    • (2003) J Neurosci Res , vol.71 , pp. 659-669
    • Chong, Z.Z.1    Lin, S.H.2    Kang, J.Q.3    Maiese, K.4
  • 14
    • 0037016065 scopus 로고    scopus 로고
    • Erythropoietin is a novel vascular protectant through activation of Akt1 and mitochondrial modulation of cysteine proteases
    • Chong ZZ, Kang JQ, Maiese K. Erythropoietin is a novel vascular protectant through activation of Akt1 and mitochondrial modulation of cysteine proteases. Circulation. 2002;106:2973-2979.
    • (2002) Circulation , vol.106 , pp. 2973-2979
    • Chong, Z.Z.1    Kang, J.Q.2    Maiese, K.3
  • 15
    • 85047691007 scopus 로고    scopus 로고
    • A novel protective effect of erythropoietin in the infarcted heart
    • Parsa CJ, Matsumoto A, Kim J, et al. A novel protective effect of erythropoietin in the infarcted heart. J Clin Invest 2003;112:999-1007.
    • (2003) J Clin Invest , vol.112 , pp. 999-1007
    • Parsa, C.J.1    Matsumoto, A.2    Kim, J.3
  • 16
    • 0035914398 scopus 로고    scopus 로고
    • Erythropoietin receptor-mediated inhibition of exocytotic glutamate release confers neuroprotection during chemical ischemia
    • Kawakami M, Sekiguchi M, Sato K, Kozaki S, Takahashi M. Erythropoietin receptor-mediated inhibition of exocytotic glutamate release confers neuroprotection during chemical ischemia. J Biol Chem. 2001;276:39469-39475.
    • (2001) J Biol Chem , vol.276 , pp. 39469-39475
    • Kawakami, M.1    Sekiguchi, M.2    Sato, K.3    Kozaki, S.4    Takahashi, M.5
  • 17
    • 11144308859 scopus 로고    scopus 로고
    • Activating Akt and the brain's resources to drive cellular survival and prevent inflammatory injury
    • Chong ZZ, Li F, Maiese K. Activating Akt and the brain's resources to drive cellular survival and prevent inflammatory injury. Histol Histopathol. 2005;20:299-315.
    • (2005) Histol Histopathol , vol.20 , pp. 299-315
    • Chong, Z.Z.1    Li, F.2    Maiese, K.3
  • 18
    • 0037338625 scopus 로고    scopus 로고
    • Apaf-1, Bcl-xL, cytochrome c, and caspase-9 form the critical elements for cerebral vascular protection by erythropoietin
    • Chong ZZ, Kang JQ, Maiese K. Apaf-1, Bcl-xL, cytochrome c, and caspase-9 form the critical elements for cerebral vascular protection by erythropoietin. J Cereb Blood Flow Metab. 2003;23:320-330.
    • (2003) J Cereb Blood Flow Metab , vol.23 , pp. 320-330
    • Chong, Z.Z.1    Kang, J.Q.2    Maiese, K.3
  • 19
    • 0042355359 scopus 로고    scopus 로고
    • Critical role for Akt1 in the modulation of apoptotic phosphatidylserine exposure and microglial activation
    • Kang JQ, Chong ZZ, Maiese K. Critical role for Akt1 in the modulation of apoptotic phosphatidylserine exposure and microglial activation. Mol Pharmacol. 2003;64:557-569.
    • (2003) Mol Pharmacol , vol.64 , pp. 557-569
    • Kang, J.Q.1    Chong, Z.Z.2    Maiese, K.3
  • 20
    • 0036703627 scopus 로고    scopus 로고
    • Neuroprotection by hypoxic preconditioning requires sequential activation of vascular endothelial growth factor receptor and Akt
    • Wick A, Wick W, Waltenberger J, Weller M, Dichgans J, Schulz JB. Neuroprotection by hypoxic preconditioning requires sequential activation of vascular endothelial growth factor receptor and Akt. J Neurosci. 2002;22:6401-6407.
    • (2002) J Neurosci , vol.22 , pp. 6401-6407
    • Wick, A.1    Wick, W.2    Waltenberger, J.3    Weller, M.4    Dichgans, J.5    Schulz, J.B.6
  • 21
    • 10744222516 scopus 로고    scopus 로고
    • Erythropoietin protects the developing brain against N-methyl-D-aspartate receptor antagonist neurotoxicity
    • Dzietko M, Felderhoff-Mueser U, Sifringer M, et al. Erythropoietin protects the developing brain against N-methyl-D-aspartate receptor antagonist neurotoxicity. Neurobiol Dis. 2004;15:177-187.
    • (2004) Neurobiol Dis , vol.15 , pp. 177-187
    • Dzietko, M.1    Felderhoff-Mueser, U.2    Sifringer, M.3
  • 22
    • 5644245234 scopus 로고    scopus 로고
    • Erythropoietin in the brain: Can the promise to protect be fulfilled?
    • Maiese K, Li F, Chong ZZ. Erythropoietin in the brain: can the promise to protect be fulfilled? Trends Pharmacol Sci. 2004;25:577-583.
    • (2004) Trends Pharmacol Sci , vol.25 , pp. 577-583
    • Maiese, K.1    Li, F.2    Chong, Z.Z.3
  • 23
    • 3042730681 scopus 로고    scopus 로고
    • The NAD+ precursor nicotinamide governs neuronal survival during oxidative stress through protein kinase B coupled to FOXO3a and mitochondrial membrane potential
    • Chong ZZ, Lin SH, Maiese K. The NAD+ precursor nicotinamide governs neuronal survival during oxidative stress through protein kinase B coupled to FOXO3a and mitochondrial membrane potential. J Cereb Blood Flow Metab. 2004;24:728-743.
    • (2004) J Cereb Blood Flow Metab , vol.24 , pp. 728-743
    • Chong, Z.Z.1    Lin, S.H.2    Maiese, K.3
  • 24
    • 0033582929 scopus 로고    scopus 로고
    • Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor
    • Brunet A, Bonni A, Zigmond MJ, et al. Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor. Cell. 1999;96:857-868.
    • (1999) Cell , vol.96 , pp. 857-868
    • Brunet, A.1    Bonni, A.2    Zigmond, M.J.3
  • 25
    • 85047695408 scopus 로고    scopus 로고
    • Phosphorylation of forkhead transcription factors by erythropoietin and stem cell factor prevents acetylation and their interaction with coactivator p300 in erythroid progenitor cells
    • Mahmud DL, G-Amlak M, Deb DK, Platanias LC, Uddin S, Wickrema A. Phosphorylation of forkhead transcription factors by erythropoietin and stem cell factor prevents acetylation and their interaction with coactivator p300 in erythroid progenitor cells. Oncogene. 2002;21:1556-1562.
    • (2002) Oncogene , vol.21 , pp. 1556-1562
    • Mahmud, D.L.1    G-Amlak, M.2    Deb, D.K.3    Platanias, L.C.4    Uddin, S.5    Wickrema, A.6
  • 26
    • 0035469857 scopus 로고    scopus 로고
    • Growth factor withdrawal from primary human erythroid progenitors induces apoptosis through a pathway involving glycogen synthase kinase-3 and Bax
    • Somervaille TC, Linch DC, Khwaja A. Growth factor withdrawal from primary human erythroid progenitors induces apoptosis through a pathway involving glycogen synthase kinase-3 and Bax. Blood. 2001; 98:1374-1381.
    • (2001) Blood , vol.98 , pp. 1374-1381
    • Somervaille, T.C.1    Linch, D.C.2    Khwaja, A.3
  • 27
    • 0035894847 scopus 로고    scopus 로고
    • Erythropoietin regulates the in vitro and in vivo production of neuronal progenitors by mammalian forebrain neural stem cells
    • Shingo T, Sorokan ST, Shimazaki T, Weiss S. Erythropoietin regulates the in vitro and in vivo production of neuronal progenitors by mammalian forebrain neural stem cells. J Neurosci. 2001;21:9733-9743.
    • (2001) J Neurosci , vol.21 , pp. 9733-9743
    • Shingo, T.1    Sorokan, S.T.2    Shimazaki, T.3    Weiss, S.4
  • 28
    • 0036896201 scopus 로고    scopus 로고
    • Erythropoietin is a paracrine mediator of ischemic tolerance in the brain: Evidence from an in vitro model
    • Ruscher K, Freyer D, Karsch M, et al. Erythropoietin is a paracrine mediator of ischemic tolerance in the brain: evidence from an in vitro model. J Neurosci. 2002;22:10291-10301.
    • (2002) J Neurosci , vol.22 , pp. 10291-10301
    • Ruscher, K.1    Freyer, D.2    Karsch, M.3
  • 29
    • 3042638808 scopus 로고    scopus 로고
    • Erythropoietin improves long-term spatial memory deficits and brain injury following neonatal hypoxia-ischemia in rats
    • Kumral A, Uysal N, Tugyan K, et al. Erythropoietin improves long-term spatial memory deficits and brain injury following neonatal hypoxia-ischemia in rats. Behav Brain Res. 2004;153:77-86.
    • (2004) Behav Brain Res , vol.153 , pp. 77-86
    • Kumral, A.1    Uysal, N.2    Tugyan, K.3
  • 30
    • 1642269715 scopus 로고    scopus 로고
    • Erythropoietin exerts neuroprotection after acute spinal cord injury in rats: Effect on lipid peroxidation and early ultrastructural findings
    • Kaptanoglu E, Solaroglu I, Okutan O, Surucu HS, Akbiyik F, Beskonakli E. Erythropoietin exerts neuroprotection after acute spinal cord injury in rats: effect on lipid peroxidation and early ultrastructural findings. Neurosurg Rev. 2004;27:113-120.
    • (2004) Neurosurg Rev , vol.27 , pp. 113-120
    • Kaptanoglu, E.1    Solaroglu, I.2    Okutan, O.3    Surucu, H.S.4    Akbiyik, F.5    Beskonakli, E.6
  • 31
    • 0242489261 scopus 로고    scopus 로고
    • Central nervous system frontiers for the use of erythropoietin
    • Olsen NV. Central nervous system frontiers for the use of erythropoietin. Clin Infect Dis. 2003;37(suppl 4):S323-5330.
    • (2003) Clin Infect Dis , vol.37 , Issue.SUPPL. 4
    • Olsen, N.V.1
  • 32
    • 2442461973 scopus 로고    scopus 로고
    • Akt1 drives endothelial cell membrane asymmetry and microglial activation through Bcl-x(L) and caspase 1, 3, and 9
    • Chong ZZ, Kang JQ, Maiese K. Akt1 drives endothelial cell membrane asymmetry and microglial activation through Bcl-x(L) and caspase 1, 3, and 9. Exp Cell Res. 2004;296:196-207.
    • (2004) Exp Cell Res , vol.296 , pp. 196-207
    • Chong, Z.Z.1    Kang, J.Q.2    Maiese, K.3
  • 34
    • 0042738942 scopus 로고    scopus 로고
    • Erythropoietin is a potent physiologic stimulus for endothelial progenitor cell mobilization
    • Heeschen C, Aicher A, Lehmann R, et al. Erythropoietin is a potent physiologic stimulus for endothelial progenitor cell mobilization. Blood. 2003;102: 1340-1346.
    • (2003) Blood , vol.102 , pp. 1340-1346
    • Heeschen, C.1    Aicher, A.2    Lehmann, R.3
  • 35
    • 0028901357 scopus 로고
    • Recombinant human erythropoietin stimulates angiogenesis in vitro
    • Carlini RG, Reyes AA, Rothstein M. Recombinant human erythropoietin stimulates angiogenesis in vitro. Kidney Int. 1995;47:740-745.
    • (1995) Kidney Int , vol.47 , pp. 740-745
    • Carlini, R.G.1    Reyes, A.A.2    Rothstein, M.3
  • 37
    • 2442714969 scopus 로고    scopus 로고
    • Cardioprotective effects of erythropoietin in the reperfused ischemic heart: A potential role for cardiac fibroblasts
    • Parsa CJ, Kim J, Riel RU, et al. Cardioprotective effects of erythropoietin in the reperfused ischemic heart: a potential role for cardiac fibroblasts. J Biol Chem. 2004;279:20655-20662.
    • (2004) J Biol Chem , vol.279 , pp. 20655-20662
    • Parsa, C.J.1    Kim, J.2    Riel, R.U.3
  • 38
    • 0141593556 scopus 로고    scopus 로고
    • Erythropoietin reduces myocardial infarction and left ventricular functional decline after coronary artery ligation in rats
    • Moon C, Krawczyk M, Ahn D, et al. Erythropoietin reduces myocardial infarction and left ventricular functional decline after coronary artery ligation in rats. Proc Natl Acad Sci USA. 2003;100:11612-11617.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 11612-11617
    • Moon, C.1    Krawczyk, M.2    Ahn, D.3
  • 39
    • 0026729184 scopus 로고
    • Changes in left ventricular size, wall thickness, and function in anemic patients treated with recombinant human erythropoietin
    • Goldberg N, Lundin AP, Delano B, Friedman EA, Stein RA. Changes in left ventricular size, wall thickness, and function in anemic patients treated with recombinant human erythropoietin. Am Heart J. 1992; 124:424-427.
    • (1992) Am Heart J , vol.124 , pp. 424-427
    • Goldberg, N.1    Lundin, A.P.2    Delano, B.3    Friedman, E.A.4    Stein, R.A.5
  • 40
    • 0035370037 scopus 로고    scopus 로고
    • The effect of correction of mild anemia in severe, resistant congestive heart failure using subcutaneous erythropoietin and intravenous iron: A randomized controlled study
    • Silverberg DS, Wexler D, Sheps D, et al. The effect of correction of mild anemia in severe, resistant congestive heart failure using subcutaneous erythropoietin and intravenous iron: a randomized controlled study. J Am Coll Cardiol. 2001;37:1775-1780.
    • (2001) J Am Coll Cardiol , vol.37 , pp. 1775-1780
    • Silverberg, D.S.1    Wexler, D.2    Sheps, D.3
  • 41
    • 12244284657 scopus 로고    scopus 로고
    • The effect of correction of anaemia in diabetics and non-diabetics with severe resistant congestive heart failure and chronic renal failure by subcutaneous erythropoietin and intravenous iron
    • Silverberg DS, Wexler D, Blum M, et al. The effect of correction of anaemia in diabetics and non-diabetics with severe resistant congestive heart failure and chronic renal failure by subcutaneous erythropoietin and intravenous iron. Nephrol Dial Transplant. 2003;18:141-146.
    • (2003) Nephrol Dial Transplant , vol.18 , pp. 141-146
    • Silverberg, D.S.1    Wexler, D.2    Blum, M.3
  • 42
    • 0037458127 scopus 로고    scopus 로고
    • Effect of erythropoietin on exercise capacity in patients with moderate to severe chronic heart failure
    • Mancini DM, Katz SD, Lang CC, LaManca J, Hudaihed A, And rone AS. Effect of erythropoietin on exercise capacity in patients with moderate to severe chronic heart failure. Circulation. 2003;107:294-299.
    • (2003) Circulation , vol.107 , pp. 294-299
    • Mancini, D.M.1    Katz, S.D.2    Lang, C.C.3    LaManca, J.4    Hudaihed, A.5    Androne, A.S.6
  • 43
    • 0141888206 scopus 로고    scopus 로고
    • Researchers probe anemia-heart failure link
    • Mitka M. Researchers probe anemia-heart failure link. JAMA. 2003;290:1835-1838.
    • (2003) JAMA , vol.290 , pp. 1835-1838
    • Mitka, M.1
  • 44
    • 7444253390 scopus 로고    scopus 로고
    • Beneficial and ominous aspects of the pleiotropic action of erythropoietin
    • Jelkmann W, Wagner K. Beneficial and ominous aspects of the pleiotropic action of erythropoietin. Ann Hematol. 2004;83:673-686.
    • (2004) Ann Hematol , vol.83 , pp. 673-686
    • Jelkmann, W.1    Wagner, K.2
  • 48
    • 0034603608 scopus 로고    scopus 로고
    • Hemodynamic changes during aging associated with cerebral blood flow and impaired cognitive function
    • Ajmani RS, Metter EJ, Jaykumar R, et al. Hemodynamic changes during aging associated with cerebral blood flow and impaired cognitive function. Neurobiol Aging. 2000;21:257-269.
    • (2000) Neurobiol Aging , vol.21 , pp. 257-269
    • Ajmani, R.S.1    Metter, E.J.2    Jaykumar, R.3
  • 49
  • 50
    • 0034674778 scopus 로고    scopus 로고
    • Proteasomes regulate the duration of erythropoietin receptor activation by controlling down-regulation of cell surface receptors
    • Verdier F, Walrafen P, Hubert N, et al. Proteasomes regulate the duration of erythropoietin receptor activation by controlling down-regulation of cell surface receptors. J Biol Chem. 2000;275:18375-18381.
    • (2000) J Biol Chem , vol.275 , pp. 18375-18381
    • Verdier, F.1    Walrafen, P.2    Hubert, N.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.