Catalytic Properties of the Asparaginyl Hydroxylase (FIH) in the Oxygen Sensing Pathway Are Distinct from Those of Its Prolyl 4-Hydroxylases

Journal of Biological Chemistry

Volumn 279, Issue 11, 2004, Pages 9899-9904

  Koivunen, Peppi ^a   Hirsilä, Maija ^a   Günzler, Volkmar ^b   Kivirikko, Kari I ^a   Myllyharju, Johanna ^a  

^a UNIVERSITY OF OULU   (Finland)

^b FIBROGEN INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CATALYSIS; COLLAGEN; DIMERS; ENZYMES; HYDROXYLATION; OXYGEN;

INHIBITORS; PEPTIDES;

BIOCHEMISTRY;

ASPARAGINYL HYDROXYLASE; HYPOXIA INDUCIBLE FACTOR 1; OXYGENASE; PROCOLLAGEN PROLINE 2 OXOGLUTARATE 4 DIOXYGENASE; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

ALPHA CHAIN; ANIMAL CELL; ARTICLE; CATALYSIS; ENDOPLASMIC RETICULUM; ENZYME ACTIVITY; ENZYME METABOLISM; ENZYME SPECIFICITY; GENE TARGETING; HYDROXYLATION; HYPOXIA; MOLECULAR RECOGNITION; NONHUMAN; NUCLEOTIDE SEQUENCE; OXYGEN TRANSPORT; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; TRANSCRIPTION REGULATION;

ANIMALS; ANOXIA; BINDING SITES; CATALYSIS; CELL LINE; DIMERIZATION; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROPHORESIS, POLYACRYLAMIDE GEL; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; INHIBITORY CONCENTRATION 50; INSECTS; KETOGLUTARIC ACIDS; KINETICS; MIXED FUNCTION OXYGENASES; MOLECULAR SEQUENCE DATA; NUCLEAR PROTEINS; OXYGEN; PEPTIDES; PROCOLLAGEN-PROLINE DIOXYGENASE; PROLINE; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS; REPRESSOR PROTEINS; TIME FACTORS; TRANS-ACTIVATORS; TRANSCRIPTION FACTORS;

ANIMALIA;

EID: 1642315195     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M312254200     Document Type: Article

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