Cyclosporin A prevents the hypoxic adaptation by activating hypoxia-inducible factor-1α Pro-564 hydroxylation

Journal of Biological Chemistry

Volumn 278, Issue 17, 2003, Pages 15406-15411

  D'Angelo, Gisela ^a   Duplan, Eric ^a   Vigne, Paul ^a   Frelin, Christian ^a  

^a INSTITUT DE PHARMACOLOGIE MOLÉCULAIRE ET CELLULAIRE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

BIOASSAY; BIODEGRADATION; ENZYME INHIBITION; ENZYMES; GENES; HYDROXYLATION;

MITOCHONDRIA;

BIOCHEMISTRY;

2 OXOGLUTARIC ACID; ALANINE; CYCLOSPORIN A; GLUTATHIONE TRANSFERASE; GREEN FLUORESCENT PROTEIN; HYBRID PROTEIN; HYDROXYPROLINE; HYPOXIA INDUCIBLE FACTOR 1ALPHA; OXYGEN; OXYGENASE; PROCOLLAGEN PROLINE 2 OXOGLUTARATE 4 DIOXYGENASE; PROLINE; PROTEASOME; UBIQUITIN;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL NUCLEUS; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INHIBITION; GENE ACTIVATION; GENE INDUCTION; GENE TARGETING; GENETIC TRANSCRIPTION; HYDROXYLATION; HYPOXIA; NEPHROTOXICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN INTERACTION; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; PROTEIN TRANSPORT; RAT; REPORTER GENE; SIGNAL TRANSDUCTION; VON HIPPEL LINDAU DISEASE;

ADAPTATION, PHYSIOLOGICAL; ANIMALS; ANOXIA; CYCLOSPORINE; HYDROXYLATION; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; KIDNEY; PROCOLLAGEN-PROLINE DIOXYGENASE; PROLINE; RATS; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC;

ANIMALIA;

EID: 0038688765     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M211293200     Document Type: Article

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