-
1
-
-
0033961747
-
Two-year syndromal and functional recovery in 219 cases of first-episode major affective disorder with psychotic features
-
Tohen M., Hennen J., Zarate C. M. Jr., et al. (2000) Two-year syndromal and functional recovery in 219 cases of first-episode major affective disorder with psychotic features. Am. J. Psychiatry 157, 220-228.
-
(2000)
Am. J. Psychiatry
, vol.157
, pp. 220-228
-
-
Tohen, M.1
Hennen, J.2
Zarate Jr., C.M.3
-
2
-
-
0034880213
-
Prevalence and clinical correlates of residual depressive symptoms in bipolar II disorder
-
Benazzi F. (2001) Prevalence and clinical correlates of residual depressive symptoms in bipolar II disorder. Psychother. Psychosom. 70, 232-238.
-
(2001)
Psychother. Psychosom.
, vol.70
, pp. 232-238
-
-
Benazzi, F.1
-
3
-
-
0029834951
-
Prodromal and residual symptoms in bipolar I disorder
-
Keitner G. I., Solomon D. A., Ryan C. E., et al. (1996) Prodromal and residual symptoms in bipolar I disorder. Compr. Psychiatry 37, 362-367.
-
(1996)
Compr. Psychiatry
, vol.37
, pp. 362-367
-
-
Keitner, G.I.1
Solomon, D.A.2
Ryan, C.E.3
-
4
-
-
0028815588
-
Relapse and impairment in bipolar disorder
-
Gitlin M. J., Swendsen J., Heller T. L., and Hammen C. (1995) Relapse and impairment in bipolar disorder. Am. J. Psychiatry 152, 1635-1640.
-
(1995)
Am. J. Psychiatry
, vol.152
, pp. 1635-1640
-
-
Gitlin, M.J.1
Swendsen, J.2
Heller, T.L.3
Hammen, C.4
-
5
-
-
0033806610
-
Functional impairment and cognition in bipolar disorder
-
Zarate C. A. Jr., Tohen M., Land M., and Cavanagh S. (2000) Functional impairment and cognition in bipolar disorder. Psychiatr. Q. 71, 309-329.
-
(2000)
Psychiatr. Q.
, vol.71
, pp. 309-329
-
-
Zarate Jr., C.A.1
Tohen, M.2
Land, M.3
Cavanagh, S.4
-
6
-
-
0035128832
-
A review of psychosocial outcome in patients with bipolar disorder
-
MacQueen G. M., Young L. T., and Joffe R. T. (2001) A review of psychosocial outcome in patients with bipolar disorder. Acta. Psychiatr. Scand. 103, 163-170.
-
(2001)
Acta. Psychiatr. Scand.
, vol.103
, pp. 163-170
-
-
MacQueen, G.M.1
Young, L.T.2
Joffe, R.T.3
-
7
-
-
0031001720
-
Alternative projections of mortality and disability by cause 1990-2020: Global Burden of Disease Study
-
Murray C. J. and Lopez A. D. (1997) Alternative projections of mortality and disability by cause 1990-2020: Global Burden of Disease Study. Lancet 349, 1498-1504.
-
(1997)
Lancet
, vol.349
, pp. 1498-1504
-
-
Murray, C.J.1
Lopez, A.D.2
-
8
-
-
0031822289
-
The relationship of depression to cardiovascular disease: Epidemiology, biology, and treatment
-
Musselman D. L., Evans D. L., and Nemeroff C. B. (1998) The relationship of depression to cardiovascular disease: epidemiology, biology, and treatment. Arch. Gen. Psychiatry 55, 580-592.
-
(1998)
Arch. Gen. Psychiatry
, vol.55
, pp. 580-592
-
-
Musselman, D.L.1
Evans, D.L.2
Nemeroff, C.B.3
-
9
-
-
0029823520
-
Bone mineral density in women with depression
-
Michelson D., Stratakis C., Hill L., et al. (1996) Bone mineral density in women with depression. N. Engl. J. Med. 335, 1176-1181.
-
(1996)
N. Engl. J. Med.
, vol.335
, pp. 1176-1181
-
-
Michelson, D.1
Stratakis, C.2
Hill, L.3
-
10
-
-
0034722749
-
Depression and diabetes: Impact of depressive symptoms on adherence, function, and costs
-
Ciechanowski P. S., Katon W. J., and Russo J. E. (2000) Depression and diabetes: impact of depressive symptoms on adherence, function, and costs. Arch. Intern. Med. 160, 3278-3285.
-
(2000)
Arch. Intern. Med.
, vol.160
, pp. 3278-3285
-
-
Ciechanowski, P.S.1
Katon, W.J.2
Russo, J.E.3
-
11
-
-
0036705074
-
Signaling networks in the pathophysiology and treatment of mood disorders
-
Gould T. D. and Manji H. K. (2002) Signaling networks in the pathophysiology and treatment of mood disorders. J. Psychosom. Res. 53, 687-697.
-
(2002)
J. Psychosom. Res.
, vol.53
, pp. 687-697
-
-
Gould, T.D.1
Manji, H.K.2
-
12
-
-
0033035485
-
Modulation of CNS signal transduction pathways and gene expression by mood-stabilizing agents: Therapeutic implications
-
Manji H. K., Bebchuk J. M., Moore G. J., Glitz D., Hasanat K. A., and Chen G. (1999) Modulation of CNS signal transduction pathways and gene expression by mood-stabilizing agents: therapeutic implications. J. Clin. Psychiatry 60, 27-39; discussion 40-21, 113-116.
-
(1999)
J. Clin. Psychiatry
, vol.60
, pp. 27-39
-
-
Manji, H.K.1
Bebchuk, J.M.2
Moore, G.J.3
Glitz, D.4
Hasanat, K.A.5
Chen, G.6
-
13
-
-
0030455770
-
Regulation of signal transduction pathways by mood-stabilizing agents: Implications for the delayed onset of therapeutic efficacy
-
Manji H. K., Chen G., Hsiao J. K., Risby E. D., Masana M. I., and Potter W. Z. (1996) Regulation of signal transduction pathways by mood-stabilizing agents: implications for the delayed onset of therapeutic efficacy. J. Clin. Psychiatry 57, 34-46; discussion 47-38.
-
(1996)
J. Clin. Psychiatry
, vol.57
, pp. 34-46
-
-
Manji, H.K.1
Chen, G.2
Hsiao, J.K.3
Risby, E.D.4
Masana, M.I.5
Potter, W.Z.6
-
14
-
-
0027944371
-
Chronic sodium valproate selectively decreases protein kinase C alpha and epsilon in vitro
-
Chen G., Manji H. K., Hawver D. B., Wright C. B., and Potter W. Z. (1994) Chronic sodium valproate selectively decreases protein kinase C alpha and epsilon in vitro. J. Neurochem. 63, 2361-2364.
-
(1994)
J. Neurochem.
, vol.63
, pp. 2361-2364
-
-
Chen, G.1
Manji, H.K.2
Hawver, D.B.3
Wright, C.B.4
Potter, W.Z.5
-
15
-
-
0037118050
-
A common mechanism of action for three mood-stabilizing drugs
-
Williams R. S., Cheng L., Mudge A. W., and Harwood A. J. (2002) A common mechanism of action for three mood-stabilizing drugs. Nature 417, 292-295.
-
(2002)
Nature
, vol.417
, pp. 292-295
-
-
Williams, R.S.1
Cheng, L.2
Mudge, A.W.3
Harwood, A.J.4
-
16
-
-
0030454553
-
Myristoylated alanine-rich C kinase substrate (MARCKS): A molecular target for the therapeutic action of mood stabilizers in the brain?
-
Lenox R. H., McNamara R. K., Watterson J. M., and Watson D. G. (1996) Myristoylated alanine-rich C kinase substrate (MARCKS): a molecular target for the therapeutic action of mood stabilizers in the brain? J. Clin. Psychiatry 57, 23-31; discussion 32-33.
-
(1996)
J. Clin. Psychiatry
, vol.57
, pp. 23-31
-
-
Lenox, R.H.1
McNamara, R.K.2
Watterson, J.M.3
Watson, D.G.4
-
17
-
-
0037219341
-
Molecular basis of lithium action: Integration of lithium-responsive signaling and gene expression networks
-
Lenox R. H. and Wang L. (2003) Molecular basis of lithium action: integration of lithium-responsive signaling and gene expression networks. Mol. Psychiatry 8, 135-144.
-
(2003)
Mol. Psychiatry
, vol.8
, pp. 135-144
-
-
Lenox, R.H.1
Wang, L.2
-
18
-
-
0037688084
-
Finding the intracellular signaling pathways affected by mood disorder treatments
-
Coyle J. T. and Duman R. S. (2003) Finding the intracellular signaling pathways affected by mood disorder treatments. Neuron 38, 157-160.
-
(2003)
Neuron
, vol.38
, pp. 157-160
-
-
Coyle, J.T.1
Duman, R.S.2
-
19
-
-
0038771254
-
Search for a common mechanism of mood stabilizers
-
Harwood A. J. and Agam G. (2003) Search for a common mechanism of mood stabilizers. Biochem. Pharmacol. 66, 179-189.
-
(2003)
Biochem. Pharmacol.
, vol.66
, pp. 179-189
-
-
Harwood, A.J.1
Agam, G.2
-
20
-
-
0003123757
-
Psychopharmacology of mood stabilizers
-
Buckley P. F. and Waddington J. L., eds. Oxford: Butterworth-Heinemann
-
Post R. M. (2000) Psychopharmacology of mood stabilizers. In: Schizophrenia and Mood Disorders: The New Drug Therapies in Clinical Practice., Buckley P. F. and Waddington J. L., eds. Oxford: Butterworth-Heinemann, pp. 127-154.
-
(2000)
Schizophrenia and Mood Disorders: The New Drug Therapies in Clinical Practice
, pp. 127-154
-
-
Post, R.M.1
-
21
-
-
0034805180
-
Lithium inhibits glycogen synthase kinase-3 by competition for magnesium
-
Ryves W. J. and Harwood A. J. (2001) Lithium inhibits glycogen synthase kinase-3 by competition for magnesium. Biochem. Biophys. Res. Commun. 280, 720-725.
-
(2001)
Biochem. Biophys. Res. Commun.
, vol.280
, pp. 720-725
-
-
Ryves, W.J.1
Harwood, A.J.2
-
22
-
-
0034306450
-
Specificity and mechanism of action of some commonly used protein kinase inhibitors
-
Davies S. P., Reddy H., Caivano M., and Cohen P. (2000) Specificity and mechanism of action of some commonly used protein kinase inhibitors. Biochem. J. 351, 95-105.
-
(2000)
Biochem. J.
, vol.351
, pp. 95-105
-
-
Davies, S.P.1
Reddy, H.2
Caivano, M.3
Cohen, P.4
-
23
-
-
0033564972
-
Comparison of fluorescence, (31)P NMR, and (7)Li NMR spectroscopic methods for investigating Li(+)/ Mg(2+) competition for biomolecules
-
Amari L., Layden B., Rong Q., Geraldes C. F., and Mota de Freitas D. (1999) Comparison of fluorescence, (31)P NMR, and (7)Li NMR spectroscopic methods for investigating Li(+)/ Mg(2+) competition for biomolecules. Anal. Biochem. 272, 1-7.
-
(1999)
Anal. Biochem.
, vol.272
, pp. 1-7
-
-
Amari, L.1
Layden, B.2
Rong, Q.3
Geraldes, C.F.4
Mota De Freitas, D.5
-
24
-
-
0029036695
-
Definition of a metal-dependent/Li(+)-inhibited phosphomonoesterase protein family based upon a conserved three-dimensional core structure
-
York J. D., Ponder J. W. and Majerus P. W. (1995) Definition of a metal-dependent/Li(+)-inhibited phosphomonoesterase protein family based upon a conserved three-dimensional core structure. Proc. Natl. Acad. Sci. USA 92, 5149-5153.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 5149-5153
-
-
York, J.D.1
Ponder, J.W.2
Majerus, P.W.3
-
25
-
-
0011705053
-
Phosphoglucomutase is an in vivo lithium target in yeast
-
Masuda C. A., Xavier M. A., Mattos K. A., Galina A., and Montero-Lomeli M. (2001) Phosphoglucomutase is an in vivo lithium target in yeast. J. Biol. Chem. 10, 10.
-
(2001)
J. Biol. Chem.
, vol.10
, pp. 10
-
-
Masuda, C.A.1
Xavier, M.A.2
Mattos, K.A.3
Galina, A.4
Montero-Lomeli, M.5
-
26
-
-
0019577307
-
Lithium inhibition of phosphofructokinase
-
Kajda P. K. and Birch N. J. (1981) Lithium inhibition of phosphofructokinase. J. Inorg. Biochem. 14, 275-278.
-
(1981)
J. Inorg. Biochem.
, vol.14
, pp. 275-278
-
-
Kajda, P.K.1
Birch, N.J.2
-
27
-
-
0029776032
-
A molecular mechanism for the effect of lithium on development
-
Klein P. S. and Melton D. A. (1996) A molecular mechanism for the effect of lithium on development. Proc. Natl. Acad. Sci. USA 93, 8455-8459.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 8455-8459
-
-
Klein, P.S.1
Melton, D.A.2
-
28
-
-
0034257051
-
Mechanisms of action of valproate: A commentatory
-
Johannessen C. U. (2000) Mechanisms of action of valproate: a commentatory. Neurochem. Int. 37, 103-110.
-
(2000)
Neurochem. Int.
, vol.37
, pp. 103-110
-
-
Johannessen, C.U.1
-
29
-
-
0018774833
-
Di-n-propylacetate and GABA degradation. Preferential inhibition of succinic semialdehyde dehydrogenase and indirect inhibition of GABA-transaminase
-
van der Laan J. W., de Boer T., and Bruinvels J. (1979) Di-n-propylacetate and GABA degradation. Preferential inhibition of succinic semialdehyde dehydrogenase and indirect inhibition of GABA-transaminase. J. Neurochem. 32, 1769-1780.
-
(1979)
J. Neurochem.
, vol.32
, pp. 1769-1780
-
-
Van Der Laan, J.W.1
De Boer, T.2
Bruinvels, J.3
-
30
-
-
0016730142
-
Effects of anticonvulsant drugs on the cerebral enzymes metabolizing GABA
-
Sawaya M. C., Horton R. W., and Meldrum B. S. (1975) Effects of anticonvulsant drugs on the cerebral enzymes metabolizing GABA. Epilepsia 16, 649-655.
-
(1975)
Epilepsia
, vol.16
, pp. 649-655
-
-
Sawaya, M.C.1
Horton, R.W.2
Meldrum, B.S.3
-
31
-
-
0018084690
-
Effects of the anticonvulsant sodium valproate on gamma-aminobutyrate and aldehyde metabolism in ox brain
-
Whittle S. R. and Turner A. J. (1978) Effects of the anticonvulsant sodium valproate on gamma-aminobutyrate and aldehyde metabolism in ox brain. J. Neurochem. 31, 1453-1459.
-
(1978)
J. Neurochem.
, vol.31
, pp. 1453-1459
-
-
Whittle, S.R.1
Turner, A.J.2
-
32
-
-
0017087116
-
Proceedings: Gamma-aminobutyric acid metabolism and the anticonvulsant action of ethanolamine-o-sulphate and di-n-propylacetate
-
Anlezark G. M., Horton R. W., Meldrum B. S., Sawaya M. C., and Stephenson J. D. (1976) Proceedings: gamma-aminobutyric acid metabolism and the anticonvulsant action of ethanolamine-o-sulphate and di-n-propylacetate. Br. J. Pharmacol. 56, 383P,384P.
-
(1976)
Br. J. Pharmacol.
, vol.56
-
-
Anlezark, G.M.1
Horton, R.W.2
Meldrum, B.S.3
Sawaya, M.C.4
Stephenson, J.D.5
-
33
-
-
18244383806
-
Valproic acid defines a novel class of HDAC inhibitors inducing differentiation of transformed cells
-
Gottlicher M., Minucci S., Zhu P., et al. (2001) Valproic acid defines a novel class of HDAC inhibitors inducing differentiation of transformed cells. Embo. J. 20, 6969-6978.
-
(2001)
Embo. J.
, vol.20
, pp. 6969-6978
-
-
Gottlicher, M.1
Minucci, S.2
Zhu, P.3
-
34
-
-
0037168650
-
An epigenetic mouse model for molecular and behavioral neuropathologies related to schizophrenia vulnerability
-
Tremolizzo L., Carboni G., Ruzicka W. B., et al. (2002) An epigenetic mouse model for molecular and behavioral neuropathologies related to schizophrenia vulnerability. Proc. Natl. Acad. Sci. USA 99, 17,095-17,100.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
-
-
Tremolizzo, L.1
Carboni, G.2
Ruzicka, W.B.3
-
35
-
-
0038380334
-
Valproate administration to mice increases histone acetylation and 5-lipoxygenase content in the hippocampus
-
Yildirim E., Zhang Z., Uz T., Chen C. Q., Manev R., and Manev H. (2003) Valproate administration to mice increases histone acetylation and 5-lipoxygenase content in the hippocampus. Neurosci. Lett. 345, 141-143.
-
(2003)
Neurosci. Lett.
, vol.345
, pp. 141-143
-
-
Yildirim, E.1
Zhang, Z.2
Uz, T.3
Chen, C.Q.4
Manev, R.5
Manev, H.6
-
36
-
-
25844440405
-
In Vivo Evidence in the Brain for Lithium Inhibition of Glycogen Synthase Kinase-3
-
Gould T. D., Chen G., and Manji H. K. (2003) In Vivo Evidence in the Brain for Lithium Inhibition of Glycogen Synthase Kinase-3. In Neuropsychopharmacology.
-
(2003)
Neuropsychopharmacology
-
-
Gould, T.D.1
Chen, G.2
Manji, H.K.3
-
37
-
-
0027351998
-
Molecular machines integrate coincident synaptic signals
-
Bourne H. R. and Nicoll R. (1993) Molecular machines integrate coincident synaptic signals. Cell 72(Suppl), 65-75.
-
(1993)
Cell
, vol.72
, Issue.SUPPL.
, pp. 65-75
-
-
Bourne, H.R.1
Nicoll, R.2
-
38
-
-
0033555859
-
Emergent properties of networks of biological signaling pathways
-
Bhalla U. S. and Iyengar R. (1999) Emergent properties of networks of biological signaling pathways. Science 283, 381-387.
-
(1999)
Science
, vol.283
, pp. 381-387
-
-
Bhalla, U.S.1
Iyengar, R.2
-
39
-
-
0033515888
-
Complexity in biological signaling systems
-
Weng G., Bhalla U. S., and Iyengar R. (1999) Complexity in biological signaling systems. Science 284, 92-96.
-
(1999)
Science
, vol.284
, pp. 92-96
-
-
Weng, G.1
Bhalla, U.S.2
Iyengar, R.3
-
40
-
-
0026623287
-
G proteins: Implications for psychiatry
-
Manji H. K. (1992) G proteins: implications for psychiatry. Am. J. Psychiatry 149, 746-760.
-
(1992)
Am. J. Psychiatry
, vol.149
, pp. 746-760
-
-
Manji, H.K.1
-
41
-
-
1942454938
-
Introduction to neurotransmitters, receptors, signal transduction, and second messengers
-
Nemeroff C., ed. Arlington, VA: American Psychiatric Publishing
-
Szabo S. T., Gould T. D., and Manji H. K. (2003) Introduction to neurotransmitters, receptors, signal transduction, and second messengers. In: Textbook of Psychopharmacology, Nemeroff C., ed. Arlington, VA: American Psychiatric Publishing, pp. 3-52.
-
(2003)
Textbook of Psychopharmacology
, pp. 3-52
-
-
Szabo, S.T.1
Gould, T.D.2
Manji, H.K.3
-
42
-
-
0030454869
-
G protein-mediated signal transduction as a target of antidepressant and antibipolar drug action: Evidence from model systems
-
Rasenick M. M., Chaney K. A., and Chen J. (1996) G protein-mediated signal transduction as a target of antidepressant and antibipolar drug action: evidence from model systems. J. Clin. Psychiatry 57, 49-55; discussion 56-58.
-
(1996)
J. Clin. Psychiatry
, vol.57
, pp. 49-55
-
-
Rasenick, M.M.1
Chaney, K.A.2
Chen, J.3
-
43
-
-
0024341795
-
Neural and developmental actions of lithium: A unifying hypothesis
-
Berridge M. J., Downes C. P., and Hanley M. R. (1989) Neural and developmental actions of lithium: a unifying hypothesis. Cell 59, 411-419.
-
(1989)
Cell
, vol.59
, pp. 411-419
-
-
Berridge, M.J.1
Downes, C.P.2
Hanley, M.R.3
-
44
-
-
0017077904
-
Increased brain myo-inositol 1-phosphate in lithium-treated rats
-
Allison J. H., Blisner M. E., Holland W. H., Hipps P. P., and Sherman W. R. (1976) Increased brain myo-inositol 1-phosphate in lithium-treated rats. Biochem. Biophys. Res. Commun. 71, 664-670.
-
(1976)
Biochem. Biophys. Res. Commun.
, vol.71
, pp. 664-670
-
-
Allison, J.H.1
Blisner, M.E.2
Holland, W.H.3
Hipps, P.P.4
Sherman, W.R.5
-
45
-
-
0015242494
-
Reduced brain inositol in lithium-treated rats
-
Allison J. H. and Stewart M. A. (1971) Reduced brain inositol in lithium-treated rats. Nat. New Biol. 233, 267,268.
-
(1971)
Nat. New Biol.
, vol.233
, pp. 267
-
-
Allison, J.H.1
Stewart, M.A.2
-
46
-
-
0019127799
-
The effects of lithium ion and other agents on the activity of myo- inositol-1-phosphatase from bovine brain
-
Hallcher L. M. and Sherman W. R. (1980) The effects of lithium ion and other agents on the activity of myo- inositol-1-phosphatase from bovine brain. J. Biol. Chem. 255, 10,896-10,901.
-
(1980)
J. Biol. Chem.
, vol.255
-
-
Hallcher, L.M.1
Sherman, W.R.2
-
47
-
-
0016231591
-
Biosynthesis of myo-inositol in rat mammary gland. Isolation and properties of the enzymes
-
Naccarato W. F., Ray R. E., and Wells W. W. (1974) Biosynthesis of myo-inositol in rat mammary gland. Isolation and properties of the enzymes. Arch. Biochem. Biophys. 164, 194-201.
-
(1974)
Arch. Biochem. Biophys.
, vol.164
, pp. 194-201
-
-
Naccarato, W.F.1
Ray, R.E.2
Wells, W.W.3
-
48
-
-
0020465411
-
Lithium amplifies agonist-dependent phosphatidylinositol responses in brain and salivary glands
-
Berridge M. J., Downes C. P., and Hanley M. R. (1982) Lithium amplifies agonist-dependent phosphatidylinositol responses in brain and salivary glands. Biochem. J. 206, 587-595.
-
(1982)
Biochem. J.
, vol.206
, pp. 587-595
-
-
Berridge, M.J.1
Downes, C.P.2
Hanley, M.R.3
-
49
-
-
0033570745
-
Ziskind-Somerfeld Research Award. Protein kinase C signaling in the brain: Molecular transduction of mood stabilization in the treatment of manic-depressive illness
-
Manji H. K. and Lenox R. H. (1999) Ziskind-Somerfeld Research Award. Protein kinase C signaling in the brain: molecular transduction of mood stabilization in the treatment of manic-depressive illness. Biol. Psychiatry 46, 1328-1351.
-
(1999)
Biol. Psychiatry
, vol.46
, pp. 1328-1351
-
-
Manji, H.K.1
Lenox, R.H.2
-
50
-
-
0030272375
-
Modulation of protein kinase C isozymes and substrates by lithium: The role of myo-inositol
-
Manji H. K., Bersudsky Y., Chen G., Belmaker R. H., and Potter W. Z. (1996) Modulation of protein kinase C isozymes and substrates by lithium: the role of myo-inositol. Neuropsychopharmacology 15, 370-381.
-
(1996)
Neuropsychopharmacology
, vol.15
, pp. 370-381
-
-
Manji, H.K.1
Bersudsky, Y.2
Chen, G.3
Belmaker, R.H.4
Potter, W.Z.5
-
51
-
-
0027366278
-
Lithium decreases membrane-associated protein kinase C in hippocampus: Selectivity for the alpha isozyme
-
Manji H. K., Etcheberrigaray R., Chen G., and Olds J. L. (1993) Lithium decreases membrane-associated protein kinase C in hippocampus: selectivity for the alpha isozyme. J. Neurochem. 61, 2303-2310.
-
(1993)
J. Neurochem.
, vol.61
, pp. 2303-2310
-
-
Manji, H.K.1
Etcheberrigaray, R.2
Chen, G.3
Olds, J.L.4
-
53
-
-
0028850086
-
Selective inhibition of the expression of signal transduction proteins by lithium in nerve growth factor-differentiated PC12 cells
-
Li X. and Jope R. S. (1995) Selective inhibition of the expression of signal transduction proteins by lithium in nerve growth factor-differentiated PC12 cells. J. Neurochem. 65, 2500-2508.
-
(1995)
J. Neurochem.
, vol.65
, pp. 2500-2508
-
-
Li, X.1
Jope, R.S.2
-
54
-
-
0026567408
-
Chronic lithium administration alters a prominent PKC substrate in rat hippocampus
-
Lenox R. H., Watson D. G., Patel J., and Ellis J. (1992) Chronic lithium administration alters a prominent PKC substrate in rat hippocampus. Brain. Res. 570, 333-340.
-
(1992)
Brain. Res.
, vol.570
, pp. 333-340
-
-
Lenox, R.H.1
Watson, D.G.2
Patel, J.3
Ellis, J.4
-
55
-
-
0030036555
-
Chronic lithium-induced down-regulation of MARCKS in immortalized hippocampal cells: Potentiation by muscarinic receptor activation
-
Watson D. G. and Lenox R. H. (1996) Chronic lithium-induced down-regulation of MARCKS in immortalized hippocampal cells: potentiation by muscarinic receptor activation. J. Neurochem. 67, 767-777.
-
(1996)
J. Neurochem.
, vol.67
, pp. 767-777
-
-
Watson, D.G.1
Lenox, R.H.2
-
56
-
-
0031981038
-
Sodium valproate down-regulates the myristoylated alanine-rich C kinase substrate (MARCKS) in immortalized hippocampal cells: A property of protein kinase C-mediated mood stabilizers
-
Watson D. G., Watterson J. M., and Lenox R. H. (1998) Sodium valproate down-regulates the myristoylated alanine-rich C kinase substrate (MARCKS) in immortalized hippocampal cells: a property of protein kinase C-mediated mood stabilizers. J. Pharmacol. Exp. Ther. 285, 307-316.
-
(1998)
J. Pharmacol. Exp. Ther.
, vol.285
, pp. 307-316
-
-
Watson, D.G.1
Watterson, J.M.2
Lenox, R.H.3
-
57
-
-
0029199648
-
Neurobiology of depression: Focus on dopamine
-
Fibiger H. C. (1995) Neurobiology of depression: focus on dopamine. Adv. Biochem. Psychopharmacol. 49, 1-17.
-
(1995)
Adv. Biochem. Psychopharmacol.
, vol.49
, pp. 1-17
-
-
Fibiger, H.C.1
-
59
-
-
0043240266
-
The role of the extracellular signal-regulated kinase signaling pathway in mood modulation
-
Einat H., Yuan P., Gould T. D., et al. (2003) The role of the extracellular signal-regulated kinase signaling pathway in mood modulation. J. Neurosci. 23, 7311-7316.
-
(2003)
J. Neurosci.
, vol.23
, pp. 7311-7316
-
-
Einat, H.1
Yuan, P.2
Gould, T.D.3
-
60
-
-
0037106975
-
Preclinical models: Status of basic research in depression
-
Nestler E. J., Gould E., Manji H., et al. (2002) Preclinical models: status of basic research in depression. Biol. Psychiatry 52, 503-528.
-
(2002)
Biol. Psychiatry
, vol.52
, pp. 503-528
-
-
Nestler, E.J.1
Gould, E.2
Manji, H.3
-
61
-
-
0026621687
-
Protein kinase C and dopamine transport - 2. Effects of amphetamine in vitro
-
Giambalvo C. T. (1992) Protein kinase C and dopamine transport - 2. Effects of amphetamine in vitro. Neuropharmacology 31, 1211-1222.
-
(1992)
Neuropharmacology
, vol.31
, pp. 1211-1222
-
-
Giambalvo, C.T.1
-
62
-
-
0027385573
-
Phosphorylation of neuromodulin in rat striatum after acute and repeated, intermittent amphetamine
-
Gnegy M. E., Hong P., and Ferrell S. T. (1993) Phosphorylation of neuromodulin in rat striatum after acute and repeated, intermittent amphetamine. Brain. Res. Mol. Brain Res. 20, 289-298.
-
(1993)
Brain. Res. Mol. Brain Res.
, vol.20
, pp. 289-298
-
-
Gnegy, M.E.1
Hong, P.2
Ferrell, S.T.3
-
63
-
-
0030910710
-
Amphetamine increases the phosphorylation of neuromodulin and synapsin I in rat striatal synaptosomes
-
Iwata S., Hewlett G. H., and Gnegy M. E. (1997) Amphetamine increases the phosphorylation of neuromodulin and synapsin I in rat striatal synaptosomes. Synapse 26, 281-291.
-
(1997)
Synapse
, vol.26
, pp. 281-291
-
-
Iwata, S.1
Hewlett, G.H.2
Gnegy, M.E.3
-
64
-
-
0031443572
-
Enhanced dopamine release and phosphorylation of synapsin I and neuromodulin in striatal synaptosomes after repeated amphetamine
-
Iwata S. I., Hewlett G. H., Ferrell S. T., Kantor L., and Gnegy M. E. (1997) Enhanced dopamine release and phosphorylation of synapsin I and neuromodulin in striatal synaptosomes after repeated amphetamine. J. Pharmacol. Exp. Ther. 283, 1445-1452.
-
(1997)
J. Pharmacol. Exp. Ther.
, vol.283
, pp. 1445-1452
-
-
Iwata, S.I.1
Hewlett, G.H.2
Ferrell, S.T.3
Kantor, L.4
Gnegy, M.E.5
-
65
-
-
7444256727
-
Protein kinase C overactivity impairs prefrontal cortical regulation of working memory
-
Birnbaum S. G., Yuan P. X., Wang M., et al. (2004) Protein kinase C overactivity impairs prefrontal cortical regulation of working memory. Science 306, 882-884.
-
(2004)
Science
, vol.306
, pp. 882-884
-
-
Birnbaum, S.G.1
Yuan, P.X.2
Wang, M.3
-
66
-
-
0032744013
-
Temporal dissociation between lithium-induced changes in frontal lobe myo-inositol and clinical response in manic-depressive illness
-
Moore G. J., Bebchuk J. M., Parrish J. K., et al. (1999) Temporal dissociation between lithium-induced changes in frontal lobe myo-inositol and clinical response in manic-depressive illness. Am. J. Psychiatry 156, 1902-1908.
-
(1999)
Am. J. Psychiatry
, vol.156
, pp. 1902-1908
-
-
Moore, G.J.1
Bebchuk, J.M.2
Parrish, J.K.3
-
67
-
-
0033301364
-
Abnormalities in protein kinase C signaling and the pathophysiology of bipolar disorder
-
Hahn C. G. and Friedman E. (1999) Abnormalities in protein kinase C signaling and the pathophysiology of bipolar disorder. Bipolar Disord. 1, 81-86.
-
(1999)
Bipolar Disord.
, vol.1
, pp. 81-86
-
-
Hahn, C.G.1
Friedman, E.2
-
68
-
-
0027278902
-
Altered platelet protein kinase C activity in bipolar affective disorder, manic episode
-
Friedman E., Hoau Yan W., Levinson D., Connell T. A., and Singh H. (1993) Altered platelet protein kinase C activity in bipolar affective disorder, manic episode. Biol. Psychiatry 33, 520-525.
-
(1993)
Biol. Psychiatry
, vol.33
, pp. 520-525
-
-
Friedman, E.1
Hoau Yan, W.2
Levinson, D.3
Connell, T.A.4
Singh, H.5
-
69
-
-
0030273260
-
Enhanced protein kinase C activity and translocation in bipolar affective disorder brains
-
Wang H. Y. and Friedman E. (1996) Enhanced protein kinase C activity and translocation in bipolar affective disorder brains. Biol. Psychiatry 40, 568-575.
-
(1996)
Biol. Psychiatry
, vol.40
, pp. 568-575
-
-
Wang, H.Y.1
Friedman, E.2
-
70
-
-
0022622039
-
Lithium-induced respecification of pattern in Xenopus-laevis embryos
-
Kao K. R., Masui Y., and Elinson R. P. (1986) Lithium-induced respecification of pattern in Xenopus-laevis embryos. Nature 322, 371-373.
-
(1986)
Nature
, vol.322
, pp. 371-373
-
-
Kao, K.R.1
Masui, Y.2
Elinson, R.P.3
-
71
-
-
0028931511
-
Glycogen synthase kinase-3 and dorsoventral patterning in Xenopus embryos
-
He X., Saint-Jeannet J. P., Woodgett J. R., Varmus H. E., and Dawid I. B. (1995) Glycogen synthase kinase-3 and dorsoventral patterning in Xenopus embryos. Nature 374, 617-622.
-
(1995)
Nature
, vol.374
, pp. 617-622
-
-
He, X.1
Saint-Jeannet, J.P.2
Woodgett, J.R.3
Varmus, H.E.4
Dawid, I.B.5
-
72
-
-
0029776032
-
A molecular mechanism for the effect of lithium on development
-
Klein P. S. and Melton D. A. (1996) A molecular mechanism for the effect of lithium on development. Proc. Natl. Acad. Sci. USA 93, 8455-8459.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 8455-8459
-
-
Klein, P.S.1
Melton, D.A.2
-
73
-
-
0030449964
-
Lithium inhibits glycogen synthase kinase-3 activity and mimics wingless signalling in intact cells
-
Stambolic V., Ruel L., and Woodgett J. R. (1996) Lithium inhibits glycogen synthase kinase-3 activity and mimics wingless signalling in intact cells. Curr. Biol. 6, 1664-1668.
-
(1996)
Curr. Biol.
, vol.6
, pp. 1664-1668
-
-
Stambolic, V.1
Ruel, L.2
Woodgett, J.R.3
-
74
-
-
0036810240
-
Lithium and valproic acid: Parallels and contrasts in diverse signaling contexts
-
Gurvich N. and Klein P. S. (2002) Lithium and valproic acid: parallels and contrasts in diverse signaling contexts. Pharmacol. Ther. 96, 45-66.
-
(2002)
Pharmacol. Ther.
, vol.96
, pp. 45-66
-
-
Gurvich, N.1
Klein, P.S.2
-
75
-
-
3342955475
-
Glycogen synthase kinase-3beta haploinsufficiency mimics the behavioral and molecular effects of lithium
-
O'Brien W. T., Harper A. D., Jove F., et al. (2004) Glycogen synthase kinase-3beta haploinsufficiency mimics the behavioral and molecular effects of lithium. J. Neurosci. 24, 6791-6798.
-
(2004)
J. Neurosci.
, vol.24
, pp. 6791-6798
-
-
O'Brien, W.T.1
Harper, A.D.2
Jove, F.3
-
76
-
-
0038187674
-
GSK-3alpha regulates production of Alzheimer's disease amyloid-beta peptides
-
Phiel C. J., Wilson C. A., Lee V. M., and Klein P. S. (2003) GSK-3alpha regulates production of Alzheimer's disease amyloid-beta peptides. Nature 423, 435-439.
-
(2003)
Nature
, vol.423
, pp. 435-439
-
-
Phiel, C.J.1
Wilson, C.A.2
Lee, V.M.3
Klein, P.S.4
-
77
-
-
0033587742
-
Lithium activates the serine/threonine kinase Akt-1 and suppresses glutamate-induced inhibition of Akt-1 activity in neurons
-
Chalecka-Franaszek E. and Chuang D. M. (1999) Lithium activates the serine/threonine kinase Akt-1 and suppresses glutamate-induced inhibition of Akt-1 activity in neurons. Proc. Natl. Acad. Sci. USA 96, 8745-8750.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 8745-8750
-
-
Chalecka-Franaszek, E.1
Chuang, D.M.2
-
78
-
-
0042357237
-
Inhibitory phosphorylation of glycogen synthase kinase-3 (GSK-3) in response to lithium. Evidence for autoregulation of GSK-3
-
Zhang F., Phiel C. J., Spece L., Gurvich N., and Klein P. S. (2003) Inhibitory phosphorylation of glycogen synthase kinase-3 (GSK-3) in response to lithium. Evidence for autoregulation of GSK-3. J. Biol. Chem. 278, 33,067-33,077.
-
(2003)
J. Biol. Chem.
, vol.278
-
-
Zhang, F.1
Phiel, C.J.2
Spece, L.3
Gurvich, N.4
Klein, P.S.5
-
79
-
-
17044423920
-
Lithium-mediated phosphorylation of glycogen synthase kinase-3b involves PI3 kinase-dependent activation of protein kinase C-alpha
-
Kirshenboim N., Plotkin B., Shlomo S. B., Kaidanovich-Beilin O., and Eldar-Finkelman H. (2004) Lithium-mediated phosphorylation of glycogen synthase kinase-3b involves PI3 kinase-dependent activation of protein kinase C-alpha. J. Mol. Neurosci. 24, 237-245.
-
(2004)
J. Mol. Neurosci.
, vol.24
, pp. 237-245
-
-
Kirshenboim, N.1
Plotkin, B.2
Shlomo, S.B.3
Kaidanovich-Beilin, O.4
Eldar-Finkelman, H.5
-
80
-
-
0035477020
-
GSK3 takes centre stage more than 20 years after its discovery
-
Frame S. and Cohen P. (2001) GSK3 takes centre stage more than 20 years after its discovery. Biochem. J. 359, 1-16.
-
(2001)
Biochem. J.
, vol.359
, pp. 1-16
-
-
Frame, S.1
Cohen, P.2
-
81
-
-
1442284539
-
Glycogen synthase kinase-3: A target for novel bipolar disorder treatments
-
in press
-
Gould T. D., Zarate C. A. J., and Manji H. K. Glycogen synthase kinase-3: a target for novel bipolar disorder treatments. J. Clin. Psychiatry, in press.
-
J. Clin. Psychiatry
-
-
Gould, T.D.1
Zarate, C.A.J.2
Manji, H.K.3
-
82
-
-
0035909112
-
Judging a protein by more than its name: gsk-3
-
Woodgett J. R. (2001) Judging a protein by more than its name: gsk-3. STKE 2001, RE12.
-
(2001)
STKE
, vol.2001
-
-
Woodgett, J.R.1
-
83
-
-
0036788036
-
The wnt signaling pathway in bipolar disorder
-
Gould T. D and Manji H. K. (2002) The wnt signaling pathway in bipolar disorder. Neuroscientist 8, 497-511.
-
(2002)
Neuroscientist
, vol.8
, pp. 497-511
-
-
Gould, T.D.1
Manji, H.K.2
-
85
-
-
0036214603
-
Mood stabilizers, glycogen synthase kinase-3beta and cell survival
-
Jope R. S. and Bijur G. N. (2002) Mood stabilizers, glycogen synthase kinase-3beta and cell survival. Mol. Psychiatry 7(Suppl 1), S35-S45.
-
(2002)
Mol. Psychiatry
, vol.7
, Issue.1 SUPPL.
-
-
Jope, R.S.1
Bijur, G.N.2
-
86
-
-
0032827466
-
Lithium at 50: Have the neuroprotective effects of this unique cation been overlooked?
-
Manji H. K., Moore G. J., and Chen G. (1999) Lithium at 50: have the neuroprotective effects of this unique cation been overlooked? Biol. Psychiatry 46, 929-940.
-
(1999)
Biol. Psychiatry
, vol.46
, pp. 929-940
-
-
Manji, H.K.1
Moore, G.J.2
Chen, G.3
-
87
-
-
1842420631
-
Rapid antidepressive-like activity of specific glycogen synthase kinase-3 inhibitor and its effect on beta-catenin in mouse hippocampus
-
Kaidanovich-Beilin O., Milman A., Weizman A., Pick C. G., and Eldar-Finkelman H. (2004) Rapid antidepressive-like activity of specific glycogen synthase kinase-3 inhibitor and its effect on beta-catenin in mouse hippocampus. Biol. Psychiatry 55, 781-784.
-
(2004)
Biol. Psychiatry
, vol.55
, pp. 781-784
-
-
Kaidanovich-Beilin, O.1
Milman, A.2
Weizman, A.3
Pick, C.G.4
Eldar-Finkelman, H.5
-
88
-
-
10644255687
-
AR-A014418, a selective GSK-3 inhibitor, produces antidepressant-like effects in the forced swim test
-
Gould T. D., Einat H., Bhat R., and Manji H. K. (2004) AR-A014418, a selective GSK-3 inhibitor, produces antidepressant-like effects in the forced swim test. Int. J. Neuropsychopharmacol. 1-4.
-
(2004)
Int. J. Neuropsychopharmacol.
, pp. 1-4
-
-
Gould, T.D.1
Einat, H.2
Bhat, R.3
Manji, H.K.4
-
89
-
-
3242761438
-
In vivo regulation of glycogen synthase kinase-3beta (GSK3beta) by serotonergic activity in mouse brain
-
Li X., Zhu W., Roh M. S., Friedman A. B., Rosborough K., and Jope R. S. (2004) In vivo regulation of glycogen synthase kinase-3beta (GSK3beta) by serotonergic activity in mouse brain. Neuropsychopharmacology 29, 1426-1431.
-
(2004)
Neuropsychopharmacology
, vol.29
, pp. 1426-1431
-
-
Li, X.1
Zhu, W.2
Roh, M.S.3
Friedman, A.B.4
Rosborough, K.5
Jope, R.S.6
-
90
-
-
1842787936
-
Lithium antagonizes dopamine-dependent behaviors mediated by an AKT/glycogen synthase kinase 3 signaling cascade
-
Beaulieu J. M., Sotnikova T. D., Yao W. D., et al. (2004) Lithium antagonizes dopamine-dependent behaviors mediated by an AKT/glycogen synthase kinase 3 signaling cascade. Proc. Natl. Acad. Sci. USA 101, 5099-5104.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 5099-5104
-
-
Beaulieu, J.M.1
Sotnikova, T.D.2
Yao, W.D.3
-
92
-
-
0035965343
-
Histone deacetylase is a direct target of valproic acid, a potent anticonvulsant, mood stabilizer, and teratogen
-
Phiel C. J., Zhang F., Huang E. Y., Guenther M. G., Lazar M. A., and Klein P. S. (2001) Histone deacetylase is a direct target of valproic acid, a potent anticonvulsant, mood stabilizer, and teratogen. J. Biol. Chem. 276, 36,734-36,741.
-
(2001)
J. Biol. Chem.
, vol.276
-
-
Phiel, C.J.1
Zhang, F.2
Huang, E.Y.3
Guenther, M.G.4
Lazar, M.A.5
Klein, P.S.6
-
93
-
-
0033014180
-
The mood-stabilizing agent valproate inhibits the activity of glycogen synthase kinase-3
-
Chen G., Huang L. D., Jiang Y. M., and Manji H. K. (1999) The mood-stabilizing agent valproate inhibits the activity of glycogen synthase kinase-3. J. Neurochem. 72, 1327-1330.
-
(1999)
J. Neurochem.
, vol.72
, pp. 1327-1330
-
-
Chen, G.1
Huang, L.D.2
Jiang, Y.M.3
Manji, H.K.4
-
94
-
-
0036311668
-
Valproate Regulates GSK-3-Mediated Axonal Remodeling and Synapsin I Clustering in Developing Neurons
-
Hall A. C., Brennan A., Goold R. G., et al. (2002) Valproate Regulates GSK-3-Mediated Axonal Remodeling and Synapsin I Clustering in Developing Neurons. Mol. Cell Neurosci. 20, 257-270.
-
(2002)
Mol. Cell Neurosci.
, vol.20
, pp. 257-270
-
-
Hall, A.C.1
Brennan, A.2
Goold, R.G.3
-
95
-
-
0036103182
-
Glycogen synthase kinase 3-beta, mood stabilizers, and neuroprotection
-
Li X., Bijur G. N., and Jope R. S. (2002) Glycogen synthase kinase 3-beta, mood stabilizers, and neuroprotection. Bipolar Disorders 4, 137-144.
-
(2002)
Bipolar Disorders
, vol.4
, pp. 137-144
-
-
Li, X.1
Bijur, G.N.2
Jope, R.S.3
-
96
-
-
0034806590
-
CREB DNA binding activity is inhibited by glycogen synthase kinase-3beta and facilitated by lithium
-
Grimes A. C. and Jope R. S. (2001) CREB DNA binding activity is inhibited by glycogen synthase kinase-3beta and facilitated by lithium. J. Neurochem. 78, 1-15.
-
(2001)
J. Neurochem.
, vol.78
, pp. 1-15
-
-
Grimes, A.C.1
Jope, R.S.2
-
97
-
-
0141497898
-
Neuroimaging studies of mood disorder effects on the brain
-
Sheline Y. I. (2003) Neuroimaging studies of mood disorder effects on the brain. Biol. Psychiatry 54, 338-352.
-
(2003)
Biol. Psychiatry
, vol.54
, pp. 338-352
-
-
Sheline, Y.I.1
-
98
-
-
0034589078
-
Functional anatomical abnormalities in limbic and prefrontal cortical structures in major depression
-
Drevets W. C. (2000) Functional anatomical abnormalities in limbic and prefrontal cortical structures in major depression. Prog. Brain. Res. 126, 413-431.
-
(2000)
Prog. Brain. Res.
, vol.126
, pp. 413-431
-
-
Drevets, W.C.1
-
99
-
-
0035034203
-
The cellular neurobiology of depression
-
Manji H. K., Drevets W. C., and Charney D. S. (2001) The cellular neurobiology of depression. Nat. Med. 7, 541-547.
-
(2001)
Nat. Med.
, vol.7
, pp. 541-547
-
-
Manji, H.K.1
Drevets, W.C.2
Charney, D.S.3
-
100
-
-
0037273905
-
Neuroimaging abnormalities in the amygdala in mood disorders
-
Drevets W. C. (2003) Neuroimaging abnormalities in the amygdala in mood disorders. Ann. N. Y. Acad. Sci. 985, 420-444.
-
(2003)
Ann. N. Y. Acad. Sci.
, vol.985
, pp. 420-444
-
-
Drevets, W.C.1
-
101
-
-
0035295487
-
Impairments of neuroplasticity and cellular resilience in severe mood disorders: Implications for the development of novel therapeutics
-
Manji H. K. and Duman R. S. (2001) Impairments of neuroplasticity and cellular resilience in severe mood disorders: implications for the development of novel therapeutics. Psychopharmacol. Bull. 35, 5-49.
-
(2001)
Psychopharmacol. Bull.
, vol.35
, pp. 5-49
-
-
Manji, H.K.1
Duman, R.S.2
-
102
-
-
0035312686
-
Neuroimaging and neuropathological studies of depression: Implications for the cognitive-emotional features of mood disorders
-
Drevets W. C. (2001) Neuroimaging and neuropathological studies of depression: implications for the cognitive-emotional features of mood disorders. Curr. Opin. Neurobiol. 11, 240-249.
-
(2001)
Curr. Opin. Neurobiol.
, vol.11
, pp. 240-249
-
-
Drevets, W.C.1
-
103
-
-
0036115945
-
tric MRI studies of mood disorders: Do they distinguish unipolar and bipolar disorder?
-
Strakowski S. M., Adler C. M., and DelBello M. P. (2002) tric MRI studies of mood disorders: do they distinguish unipolar and bipolar disorder? Bipolar Disord. 4, 80-88.
-
(2002)
Bipolar Disord.
, vol.4
, pp. 80-88
-
-
Strakowski, S.M.1
Adler, C.M.2
DelBello, M.P.3
-
104
-
-
0036102198
-
tric brain imaging findings in mood disorders
-
Beyer J. L. and Krishnan K. R. (2002) tric brain imaging findings in mood disorders. Bipolar Disorders 4, 89-104.
-
(2002)
Bipolar Disorders
, vol.4
, pp. 89-104
-
-
Beyer, J.L.1
Krishnan, K.R.2
-
105
-
-
0035016906
-
Reduced glial cell density and neuronal size in the anterior cingulate cortex in major depressive disorder
-
Cotter D., Mackay D., Landau S., Kerwin R., and Everall I. (2001) Reduced glial cell density and neuronal size in the anterior cingulate cortex in major depressive disorder. Arch. Gen. Psychiatry 58, 545-553.
-
(2001)
Arch. Gen. Psychiatry
, vol.58
, pp. 545-553
-
-
Cotter, D.1
Mackay, D.2
Landau, S.3
Kerwin, R.4
Everall, I.5
-
106
-
-
0036102199
-
Cell pathology in bipolar disorder
-
Rajkowska G. (2002) Cell pathology in bipolar disorder. Bipolar Disord 4, 129-116.
-
(2002)
Bipolar Disord
, vol.4
, pp. 129-1116
-
-
Rajkowska, G.1
-
107
-
-
0031023930
-
The anatomy of mood disorders - Review of structural neuroimaging studies
-
Soares J. C. and Mann J. J. (1997) The anatomy of mood disorders - review of structural neuroimaging studies. Biol. Psychiatry 41, 86-106.
-
(1997)
Biol. Psychiatry
, vol.41
, pp. 86-106
-
-
Soares, J.C.1
Mann, J.J.2
-
108
-
-
0034666052
-
Neuroimaging in bipolar disorder: What have we learned?
-
Stoll A. L., Renshaw P. F., Yurgelun-Todd D. A., and Cohen B. M. (2000) Neuroimaging in bipolar disorder: what have we learned? Biol. Psychiatry 48, 505-517.
-
(2000)
Biol. Psychiatry
, vol.48
, pp. 505-517
-
-
Stoll, A.L.1
Renshaw, P.F.2
Yurgelun-Todd, D.A.3
Cohen, B.M.4
-
109
-
-
0030638601
-
The effects of stressful life events on depression
-
Kessler R. C. (1997) The effects of stressful life events on depression. Annu. Rev. Psychol. 48, 191-214.
-
(1997)
Annu. Rev. Psychol.
, vol.48
, pp. 191-214
-
-
Kessler, R.C.1
-
110
-
-
0032912252
-
Stress and hippocampal plasticity
-
McEwen B. S. (1999) Stress and hippocampal plasticity. Annu. Rev. Neurosci. 22, 105-122.
-
(1999)
Annu. Rev. Neurosci.
, vol.22
, pp. 105-122
-
-
McEwen, B.S.1
-
111
-
-
0036113348
-
Stress and depression: Possible links to neuron death in the hippocampus
-
Lee A. L., Ogle W. O., and Sapolsky R. M. (2002) Stress and depression: possible links to neuron death in the hippocampus. Bipolar Disorders 4, 117-128.
-
(2002)
Bipolar Disorders
, vol.4
, pp. 117-128
-
-
Lee, A.L.1
Ogle, W.O.2
Sapolsky, R.M.3
-
112
-
-
0035940405
-
Depression, antidepressants, and the shrinking hippocampus
-
Sapolsky R. M. (2001) Depression, antidepressants, and the shrinking hippocampus. Proc. Natl. Acad. Sci. USA 98, 12,320-12,322.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
-
-
Sapolsky, R.M.1
-
113
-
-
0033800486
-
Glucocorticoids and hippocampal atrophy in neuropsychiatric disorders
-
Sapolsky R. M. (2000) Glucocorticoids and hippocampal atrophy in neuropsychiatric disorders. Arch. Gen. Psychiatry 57, 925-935.
-
(2000)
Arch. Gen. Psychiatry
, vol.57
, pp. 925-935
-
-
Sapolsky, R.M.1
-
114
-
-
0141669079
-
Cell proliferation in adult hippocampus is decreased by inescapable stress: Reversal by fluoxetine treatment
-
Malberg J. E. and Duman R. S. (2003) Cell proliferation in adult hippocampus is decreased by inescapable stress: reversal by fluoxetine treatment. Neuropsychopharmacology 28, 1562-1571.
-
(2003)
Neuropsychopharmacology
, vol.28
, pp. 1562-1571
-
-
Malberg, J.E.1
Duman, R.S.2
-
115
-
-
0037293553
-
Repeated restraint stress suppresses neurogenesis and induces biphasic PSA-NCAM expression in the adult rat dentate gyrus
-
Pham K., Nacher J., Hof P. R., and McEwen B. S. (2003) Repeated restraint stress suppresses neurogenesis and induces biphasic PSA-NCAM expression in the adult rat dentate gyrus. Eur. J. Neurosci. 17, 879-886.
-
(2003)
Eur. J. Neurosci.
, vol.17
, pp. 879-886
-
-
Pham, K.1
Nacher, J.2
Hof, P.R.3
McEwen, B.S.4
-
116
-
-
0034667294
-
Regulation of hippocampal neurogenesis in adulthood
-
Gould E., Tanapat P., Rydel T., and Hastings N. (2000) Regulation of hippocampal neurogenesis in adulthood. Biol. Psychiatry 48, 715-720.
-
(2000)
Biol. Psychiatry
, vol.48
, pp. 715-720
-
-
Gould, E.1
Tanapat, P.2
Rydel, T.3
Hastings, N.4
-
117
-
-
0034718421
-
Regulation and localization of tyrosine216 phosphorylation of glycogen synthase kinase-3beta in cellular and animal models of neuronal degeneration
-
Bhat R. V., Shanley J., Correll M. P., et al. (2000) Regulation and localization of tyrosine216 phosphorylation of glycogen synthase kinase-3beta in cellular and animal models of neuronal degeneration. Proc. Natl. Acad. Sci. USA 97, 11,074-11,079.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
-
-
Bhat, R.V.1
Shanley, J.2
Correll, M.P.3
-
118
-
-
0035940752
-
An investigation of the neuroprotective effect of lithium in organotypic slice cultures of rat hippocampus exposed to oxygen and glucose deprivation
-
Cimarosti H., Rodnight R., Tavares A., et al. (2001) An investigation of the neuroprotective effect of lithium in organotypic slice cultures of rat hippocampus exposed to oxygen and glucose deprivation. Neurosci. Lett. 315, 33-36.
-
(2001)
Neurosci. Lett.
, vol.315
, pp. 33-36
-
-
Cimarosti, H.1
Rodnight, R.2
Tavares, A.3
-
119
-
-
0028356703
-
Lithium induces apoptosis in immature cerebellar granule cells but promotes survival of mature neurons
-
D'Mello S. R., Anelli R., and Calissano P. (1994) Lithium induces apoptosis in immature cerebellar granule cells but promotes survival of mature neurons. Exp. Cell. Res. 211, 332-338.
-
(1994)
Exp. Cell. Res.
, vol.211
, pp. 332-338
-
-
D'Mello, S.R.1
Anelli, R.2
Calissano, P.3
-
120
-
-
0032994237
-
Li+ protects nerve cells against destabilization of Ca2+ homeostasis and delayed death caused by removal of external Na+
-
Khodorov B., Pinelis V., Vinskaya N., Sorokina E., Grigortsevich N., and Storozhevykh T. (1999) Li+ protects nerve cells against destabilization of Ca2+ homeostasis and delayed death caused by removal of external Na+. FEBS Lett. 448, 173-176.
-
(1999)
FEBS Lett.
, vol.448
, pp. 173-176
-
-
Khodorov, B.1
Pinelis, V.2
Vinskaya, N.3
Sorokina, E.4
Grigortsevich, N.5
Storozhevykh, T.6
-
121
-
-
0032478088
-
Chronic lithium treatment robustly protects neurons in the central nervous system against excitotoxicity by inhibiting N-methyl-D-aspartate receptor-mediated calcium influx
-
Nonaka S., Hough C. J., and Chuang D. M. (1998) Chronic lithium treatment robustly protects neurons in the central nervous system against excitotoxicity by inhibiting N-methyl-D-aspartate receptor-mediated calcium influx. Proc. Natl. Acad. Sci. USA 95, 2642-2647.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 2642-2647
-
-
Nonaka, S.1
Hough, C.J.2
Chuang, D.M.3
-
122
-
-
0036328597
-
Lithium protection against glutamate excitotoxicity in rat cerebral cortical neurons: Involvement of NMDA receptor inhibition possibly by decreasing NR2B tyrosine phosphorylation
-
Hashimoto R., Hough C., Nakazawa T., Yamamoto T., and Chuang D. M. (2002) Lithium protection against glutamate excitotoxicity in rat cerebral cortical neurons: involvement of NMDA receptor inhibition possibly by decreasing NR2B tyrosine phosphorylation. J. Neurochem. 80, 589-597.
-
(2002)
J. Neurochem.
, vol.80
, pp. 589-597
-
-
Hashimoto, R.1
Hough, C.2
Nakazawa, T.3
Yamamoto, T.4
Chuang, D.M.5
-
123
-
-
25844494008
-
Valproic acid protects against glutamate-induced excitotoxicity in mature cerebellar granule cells
-
94.18
-
Kanai H., Chalecka-Franaszek E., Chen R. W., Hashimoto R., Hiroi T., and Chuang D. M. (2001) Valproic acid protects against glutamate-induced excitotoxicity in mature cerebellar granule cells. Society for Neuroscience Annual Meeting Abstract 94.18.
-
(2001)
Society for Neuroscience Annual Meeting Abstract
-
-
Kanai, H.1
Chalecka-Franaszek, E.2
Chen, R.W.3
Hashimoto, R.4
Hiroi, T.5
Chuang, D.M.6
-
124
-
-
0033525538
-
Long term lithium treatment suppresses p53 and Bax expression but increases Bcl-2 expression. A prominent role in neuroprotection against excitotoxicity
-
Chen R. W. and Chuang D. M. (1999) Long term lithium treatment suppresses p53 and Bax expression but increases Bcl-2 expression. A prominent role in neuroprotection against excitotoxicity. J. Biol. Chem. 274, 6039-6042.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 6039-6042
-
-
Chen, R.W.1
Chuang, D.M.2
-
125
-
-
0032556794
-
Partial lithium-associated protection against apoptosis induced by C2-ceramide in cerebellar granule neurons
-
Centeno F., Mora A., Fuentes J. M., Soler G., and Claro E. (1998) Partial lithium-associated protection against apoptosis induced by C2-ceramide in cerebellar granule neurons. Neuroreport 9, 4199-4203.
-
(1998)
Neuroreport
, vol.9
, pp. 4199-4203
-
-
Centeno, F.1
Mora, A.2
Fuentes, J.M.3
Soler, G.4
Claro, E.5
-
126
-
-
0031870871
-
Lithium protects rat cerebellar granule cells against apoptosis induced by anticonvulsants, phenytoin and carbamazepine
-
Nonaka S., Katsube N., and Chuang D. M. (1998) Lithium protects rat cerebellar granule cells against apoptosis induced by anticonvulsants, phenytoin and carbamazepine. J. Pharmacol. Exp. Ther. 286, 539-547.
-
(1998)
J. Pharmacol. Exp. Ther.
, vol.286
, pp. 539-547
-
-
Nonaka, S.1
Katsube, N.2
Chuang, D.M.3
-
127
-
-
0038066627
-
Valproic acid, a mood stabilizer and anticonvulsant, protects rat cerebral cortical neurons from spontaneous cell death: A role of histone deacetylase inhibition
-
Jeong M. R., Hashimoto R., Senatorov V. V., et al. (2003) Valproic acid, a mood stabilizer and anticonvulsant, protects rat cerebral cortical neurons from spontaneous cell death: a role of histone deacetylase inhibition. FEBS Lett. 542, 74-78.
-
(2003)
FEBS Lett.
, vol.542
, pp. 74-78
-
-
Jeong, M.R.1
Hashimoto, R.2
Senatorov, V.V.3
-
128
-
-
0344517353
-
Lithium protects cultured neurons against beta-amyloid-induced neurodegeneration
-
Alvarez G., Munoz-Montano J. R., Satrustegui J., Avila J., Bogonez E., and Diaz-Nido J. (1999) Lithium protects cultured neurons against beta-amyloid-induced neurodegeneration. FEBS Lett. 453, 260-264.
-
(1999)
FEBS Lett.
, vol.453
, pp. 260-264
-
-
Alvarez, G.1
Munoz-Montano, J.R.2
Satrustegui, J.3
Avila, J.4
Bogonez, E.5
Diaz-Nido, J.6
-
129
-
-
0036116367
-
Neuroprotective effects of lithium in cultured cells and animal models of diseases
-
Chuang D. M., Chen R., Chalecka-Franaszek E., et al. (2002) Neuroprotective effects of lithium in cultured cells and animal models of diseases. Bipolar Disorders 4, 129-136.
-
(2002)
Bipolar Disorders
, vol.4
, pp. 129-136
-
-
Chuang, D.M.1
Chen, R.2
Chalecka-Franaszek, E.3
-
130
-
-
0032956630
-
The mood-stabilizing agents lithium and valproate robustly increase the levels of the neuroprotective protein bcl-2 in the CNS
-
Chen G., Zeng W. Z., Yuan P. X., et al. (1999) The mood-stabilizing agents lithium and valproate robustly increase the levels of the neuroprotective protein bcl-2 in the CNS. J. Neurochem. 72, 879-882.
-
(1999)
J. Neurochem.
, vol.72
, pp. 879-882
-
-
Chen, G.1
Zeng, W.Z.2
Yuan, P.X.3
-
131
-
-
0032557889
-
Neuroprotective effects of chronic lithium on focal cerebral ischemia in rats
-
Nonaka S. and Chuang D. M. (1998) Neuroprotective effects of chronic lithium on focal cerebral ischemia in rats. Neuroreport 9, 2081-2084.
-
(1998)
Neuroreport
, vol.9
, pp. 2081-2084
-
-
Nonaka, S.1
Chuang, D.M.2
-
132
-
-
0037609376
-
Postinsult treatment with lithium reduces brain damage and facilitates neurological recovery in a rat ischemia/reperfusion model
-
Ren M., Senatorov V. V., Chen R. W., and Chuang D. M. (2003) Postinsult treatment with lithium reduces brain damage and facilitates neurological recovery in a rat ischemia/reperfusion model. Proc. Natl. Acad. Sci. USA 100, 6210-6215.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 6210-6215
-
-
Ren, M.1
Senatorov, V.V.2
Chen, R.W.3
Chuang, D.M.4
-
133
-
-
3042651448
-
Valproaic acid reduces brain damage induced by transient focal cerebral ischemia in rats: Potential roles of histone deacetylase inhibition and heat shock protein induction
-
Ren M., Leng Y., Jeong M. R., Leeds P., and Chuang D. M. (2004) Valproaic acid reduces brain damage induced by transient focal cerebral ischemia in rats: potential roles of histone deacetylase inhibition and heat shock protein induction. J. Neurochem. 89, 1358-1367.
-
(2004)
J. Neurochem.
, vol.89
, pp. 1358-1367
-
-
Ren, M.1
Leng, Y.2
Jeong, M.R.3
Leeds, P.4
Chuang, D.M.5
-
134
-
-
0035960005
-
Lithium suppresses excitotoxicity-induced striatal lesions in a rat model of Huntington's disease
-
Wei H., Qin Z. H., Senatorov V. V., et al. (2001) Lithium suppresses excitotoxicity-induced striatal lesions in a rat model of Huntington's disease. Neuroscience 106, 603-612.
-
(2001)
Neuroscience
, vol.106
, pp. 603-612
-
-
Wei, H.1
Qin, Z.H.2
Senatorov, V.V.3
-
135
-
-
0031950413
-
Regulation of neurogenesis by growth factors and neurotransmitters
-
Cameron H. A., Hazel T. G., and McKay R. D. (1998) Regulation of neurogenesis by growth factors and neurotransmitters. J. Neurobiol. 36, 287-306.
-
(1998)
J. Neurobiol.
, vol.36
, pp. 287-306
-
-
Cameron, H.A.1
Hazel, T.G.2
McKay, R.D.3
-
136
-
-
0034712047
-
Mammalian neural stem cells
-
Gage F. H. (2000) Mammalian neural stem cells. Science 287, 1433-1438.
-
(2000)
Science
, vol.287
, pp. 1433-1438
-
-
Gage, F.H.1
-
137
-
-
0036430514
-
Adult brain neurogenesis and depression
-
Jacobs B. L. (2002) Adult brain neurogenesis and depression. Brain. Behav. Immun. 16, 602-609.
-
(2002)
Brain. Behav. Immun.
, vol.16
, pp. 602-609
-
-
Jacobs, B.L.1
-
138
-
-
0033937168
-
Adult brain neurogenesis and psychiatry: A novel theory of depression
-
Jacobs B. L., Praag H., and Gage F. H. (2000) Adult brain neurogenesis and psychiatry: a novel theory of depression. Mol. Psychiatry 5, 262-269.
-
(2000)
Mol. Psychiatry
, vol.5
, pp. 262-269
-
-
Jacobs, B.L.1
Praag, H.2
Gage, F.H.3
-
139
-
-
0035669496
-
Manipulation of neural precursors in situ: Induction of neurogenesis in the neocortex of adult mice
-
Magavi S. S. and Macklis J. D. (2001) Manipulation of neural precursors in situ: induction of neurogenesis in the neocortex of adult mice. Neuropsychopharmacology 25, 816-835.
-
(2001)
Neuropsychopharmacology
, vol.25
, pp. 816-835
-
-
Magavi, S.S.1
Macklis, J.D.2
-
140
-
-
0035672760
-
Regulation of adult neurogenesis by antidepressant treatment
-
Duman R. S., Nakagawa S., and Malberg J. (2001) Regulation of adult neurogenesis by antidepressant treatment. Neuropsychopharmacology 25, 836-844.
-
(2001)
Neuropsychopharmacology
, vol.25
, pp. 836-844
-
-
Duman, R.S.1
Nakagawa, S.2
Malberg, J.3
-
141
-
-
0034671366
-
Chronic antidepressant treatment increases neurogenesis in adult rat hippocampus
-
Malberg J. E., Eisch A. J., Nestler E. J., and Duman R. S. (2000) Chronic antidepressant treatment increases neurogenesis in adult rat hippocampus. J. Neurosci. 20, 9104-9110.
-
(2000)
J. Neurosci.
, vol.20
, pp. 9104-9110
-
-
Malberg, J.E.1
Eisch, A.J.2
Nestler, E.J.3
Duman, R.S.4
-
142
-
-
0035179732
-
Antidepressants alter cell proliferation in the adult brain in vivo and in neural cultures in vitro
-
Manev H., Uz T., Smalheiser N. R., and Manev R. (2001) Antidepressants alter cell proliferation in the adult brain in vivo and in neural cultures in vitro. Eur. J. Pharmacol. 411, 67-70.
-
(2001)
Eur. J. Pharmacol.
, vol.411
, pp. 67-70
-
-
Manev, H.1
Uz, T.2
Smalheiser, N.R.3
Manev, R.4
-
143
-
-
0042528720
-
Requirement of hippocampal neurogenesis for the behavioral effects of antidepressants
-
Santarelli L., Saxe M., Gross C., et al. (2003) Requirement of hippocampal neurogenesis for the behavioral effects of antidepressants. Science 301, 805-809.
-
(2003)
Science
, vol.301
, pp. 805-809
-
-
Santarelli, L.1
Saxe, M.2
Gross, C.3
-
144
-
-
0037451782
-
Lithium stimulates progenitor proliferation in cultured brain neurons
-
Hashimoto R., Senatorov V., Kanai H., Leeds P., and Chuang D. M. (2003) Lithium stimulates progenitor proliferation in cultured brain neurons. Neuroscience 117, 55-61.
-
(2003)
Neuroscience
, vol.117
, pp. 55-61
-
-
Hashimoto, R.1
Senatorov, V.2
Kanai, H.3
Leeds, P.4
Chuang, D.M.5
-
145
-
-
0033817849
-
Enhancement of hippocampal neurogenesis by lithium
-
Chen G., Rajkowska G., Du F., Seraji-Bozorgzad N., and Manji H. K. (2000) Enhancement of hippocampal neurogenesis by lithium. J. Neurochem. 75, 1729-1734.
-
(2000)
J. Neurochem.
, vol.75
, pp. 1729-1734
-
-
Chen, G.1
Rajkowska, G.2
Du, F.3
Seraji-Bozorgzad, N.4
Manji, H.K.5
-
146
-
-
3242788185
-
Mood stabilizer valproate promotes ERK pathway-dependent cortical neuronal growth and neurogenesis
-
Hao Y., Creson T., Zhang L., et al. (2004) Mood stabilizer valproate promotes ERK pathway-dependent cortical neuronal growth and neurogenesis. J. Neurosci. 24, 6590-6599.
-
(2004)
J. Neurosci.
, vol.24
, pp. 6590-6599
-
-
Hao, Y.1
Creson, T.2
Zhang, L.3
-
147
-
-
0036368661
-
Neurotrophins and cortical development
-
McAllister A. K. (2002) Neurotrophins and cortical development. Results Probl. Cell. Differ. 39, 89-112.
-
(2002)
Results Probl. Cell. Differ.
, vol.39
, pp. 89-112
-
-
McAllister, A.K.1
-
149
-
-
0034871475
-
Neurotrophins and neuronal differentiation in the central nervous system
-
McAllister A. K. (2001) Neurotrophins and neuronal differentiation in the central nervous system. Cell. Mol. Life Sci. 58, 1054-1060.
-
(2001)
Cell. Mol. Life Sci.
, vol.58
, pp. 1054-1060
-
-
McAllister, A.K.1
-
150
-
-
0036298493
-
Downregulation of BDNF mRNA in the hippocampal dentate gyrus after re-exposure to cues previously associated with footshock
-
Rasmusson A. M., Shi L., and Duman R. (2002) Downregulation of BDNF mRNA in the hippocampal dentate gyrus after re-exposure to cues previously associated with footshock. Neuropsychopharmacology 27, 133-142.
-
(2002)
Neuropsychopharmacology
, vol.27
, pp. 133-142
-
-
Rasmusson, A.M.1
Shi, L.2
Duman, R.3
-
151
-
-
0030293881
-
Stress-induced changes in brain-derived neurotrophic factor expression are attenuated in aged Fischer 344/N rats
-
Smith M. A. and Cizza G. (1996) Stress-induced changes in brain-derived neurotrophic factor expression are attenuated in aged Fischer 344/N rats. Neurobiol. Aging 17, 859-864.
-
(1996)
Neurobiol. Aging
, vol.17
, pp. 859-864
-
-
Smith, M.A.1
Cizza, G.2
-
152
-
-
0030920788
-
Immobilization stress reduced the expression of neurotrophins and their receptors in the rat brain
-
Ueyama T., Kawai Y., Nemoto K., Sekimoto M., Tone S., and Senba E. (1997) Immobilization stress reduced the expression of neurotrophins and their receptors in the rat brain. Neurosci. Res. 28, 103-110.
-
(1997)
Neurosci. Res.
, vol.28
, pp. 103-110
-
-
Ueyama, T.1
Kawai, Y.2
Nemoto, K.3
Sekimoto, M.4
Tone, S.5
Senba, E.6
-
153
-
-
0029555826
-
Effects of stress on neurotrophic factor expression in the rat brain
-
Smith M. A., Makino S., Kvetnansky R., and Post R. M. (1995) Effects of stress on neurotrophic factor expression in the rat brain. Ann. NY Acad. Sci. 771, 234-239.
-
(1995)
Ann. NY Acad. Sci.
, vol.771
, pp. 234-239
-
-
Smith, M.A.1
Makino, S.2
Kvetnansky, R.3
Post, R.M.4
-
154
-
-
0028815653
-
Regulation of BDNF and trkB mRNA in rat brain by chronic electroconvulsive seizure and antidepressant drug treatments
-
Nibuya M., Morinobu S., and Duman R. S. (1995) Regulation of BDNF and trkB mRNA in rat brain by chronic electroconvulsive seizure and antidepressant drug treatments. J. Neurosci. 15, 7539-7547.
-
(1995)
J. Neurosci.
, vol.15
, pp. 7539-7547
-
-
Nibuya, M.1
Morinobu, S.2
Duman, R.S.3
-
155
-
-
0035881828
-
Increased hippocampal BDNF immunoreactivity in subjects treated with antidepressant medication
-
Chen B., Dowlatshahi D., MacQueen G. M., Wang J. F., and Young L. T. (2001) Increased hippocampal BDNF immunoreactivity in subjects treated with antidepressant medication. Biol. Psychiatry 50, 260-265.
-
(2001)
Biol. Psychiatry
, vol.50
, pp. 260-265
-
-
Chen, B.1
Dowlatshahi, D.2
MacQueen, G.M.3
Wang, J.F.4
Young, L.T.5
-
156
-
-
0037092425
-
Brain-derived neurotrophic factor produces antidepressant effects in behavioral models of depression
-
Shirayama Y., Chen A. C., Nakagawa S., Russell D. S., and Duman R. S. (2002) Brain-derived neurotrophic factor produces antidepressant effects in behavioral models of depression. J. Neurosci. 22, 3251-3261.
-
(2002)
J. Neurosci.
, vol.22
, pp. 3251-3261
-
-
Shirayama, Y.1
Chen, A.C.2
Nakagawa, S.3
Russell, D.S.4
Duman, R.S.5
-
157
-
-
0034795827
-
Chronic lithium treatment increases the expression of brain-derived neurotrophic factor in the rat brain
-
Fukumoto T., Morinobu S., Okamoto Y., Kagaya A., and Yamawaki S. (2001) Chronic lithium treatment increases the expression of brain-derived neurotrophic factor in the rat brain. Psychopharmacology (Berl) 158, 100-106.
-
(2001)
Psychopharmacology (Berl)
, vol.158
, pp. 100-106
-
-
Fukumoto, T.1
Morinobu, S.2
Okamoto, Y.3
Kagaya, A.4
Yamawaki, S.5
-
158
-
-
0036914074
-
Lithium induces brain-derived neurotrophic factor and activates TrkB in rodent cortical neurons: An essential step for neuroprotection against glutamate excitotoxicity
-
Hashimoto R., Takei N., Shimazu K., Christ L., Lu B., and Chuang D. M. (2002) Lithium induces brain-derived neurotrophic factor and activates TrkB in rodent cortical neurons: an essential step for neuroprotection against glutamate excitotoxicity. Neuropharmacology 43, 1173-1179.
-
(2002)
Neuropharmacology
, vol.43
, pp. 1173-1179
-
-
Hashimoto, R.1
Takei, N.2
Shimazu, K.3
Christ, L.4
Lu, B.5
Chuang, D.M.6
-
159
-
-
0037453291
-
Chronic lithium enhances hippocampal long-term potentiation, but not neurogenesis, in the aged rat dentate gyrus
-
Yu I. T., Kim J. S., Lee S. H., Lee Y. S., and Son H. (2003) Chronic lithium enhances hippocampal long-term potentiation, but not neurogenesis, in the aged rat dentate gyrus. Biochem. Biophys. Res. Commun. 303, 1193-1198.
-
(2003)
Biochem. Biophys. Res. Commun.
, vol.303
, pp. 1193-1198
-
-
Yu, I.T.1
Kim, J.S.2
Lee, S.H.3
Lee, Y.S.4
Son, H.5
-
160
-
-
0038587636
-
Lithium enhances long-term potentiation independently of hippocampal neurogenesis in the rat dentate gyrus
-
Son H., Yu I. T., Hwang S. J., et al. (2003) Lithium enhances long-term potentiation independently of hippocampal neurogenesis in the rat dentate gyrus. J. Neurochem. 85, 872-881.
-
(2003)
J. Neurochem.
, vol.85
, pp. 872-881
-
-
Son, H.1
Yu, I.T.2
Hwang, S.J.3
-
161
-
-
0034644539
-
Cell signaling by receptor tyrosine kinases
-
Schlessinger J. (2000) Cell signaling by receptor tyrosine kinases. Cell 103, 211-225.
-
(2000)
Cell
, vol.103
, pp. 211-225
-
-
Schlessinger, J.1
-
162
-
-
0035234670
-
Neurotrophins as synaptic modulators
-
Poo M. M. (2001) Neurotrophins as synaptic modulators. Nat. Rev. Neurosci. 2, 24-32.
-
(2001)
Nat. Rev. Neurosci.
, vol.2
, pp. 24-32
-
-
Poo, M.M.1
-
163
-
-
0035369840
-
Trk receptors: Mediators of neurotrophin action
-
Patapoutian A. and Reichardt L. F. (2001) Trk receptors: mediators of neurotrophin action. Curr. Opin. Neurobiol. 11, 272-280.
-
(2001)
Curr. Opin. Neurobiol.
, vol.11
, pp. 272-280
-
-
Patapoutian, A.1
Reichardt, L.F.2
-
164
-
-
0035943699
-
The mood stabilizer valproic acid activates mitogen-activated protein kinases and promotes neurite growth
-
Yuan P. X., Huang L. D., Jiang Y. M., Gutkind J. S., Manji H. K., and Chen G. (2001) The mood stabilizer valproic acid activates mitogen-activated protein kinases and promotes neurite growth. J. Biol. Chem. 276, 31,674-31,683.
-
(2001)
J. Biol. Chem.
, vol.276
-
-
Yuan, P.X.1
Huang, L.D.2
Jiang, Y.M.3
Gutkind, J.S.4
Manji, H.K.5
Chen, G.6
-
165
-
-
0033659957
-
Neuroplasticity and cellular resilience in mood disorders
-
Manji H. K., Moore G. J., Rajkowska G., and Chen G. (2000) Neuroplasticity and cellular resilience in mood disorders. Mol. Psychiatry 5, 578-593.
-
(2000)
Mol. Psychiatry
, vol.5
, pp. 578-593
-
-
Manji, H.K.1
Moore, G.J.2
Rajkowska, G.3
Chen, G.4
-
166
-
-
0037249456
-
Support of retinal ganglion cell survival and axon regeneration by lithium through a Bcl-2-dependent mechanism
-
Huang X., Wu D. Y., Chen G., Manji H., and Chen D. F. (2003) Support of retinal ganglion cell survival and axon regeneration by lithium through a Bcl-2-dependent mechanism. Invest. Ophthalmol. Vis. Sci. 44, 347-354.
-
(2003)
Invest. Ophthalmol. Vis. Sci.
, vol.44
, pp. 347-354
-
-
Huang, X.1
Wu, D.Y.2
Chen, G.3
Manji, H.4
Chen, D.F.5
-
167
-
-
4243165658
-
Emerging experimental therapeutics for bipolar disorder: Clues from the molecular pathophysiology
-
Quiroz J., Singh J., Gould T. D., Denicoff K. D., Zarate C. A., and Manji H. K. (2004) Emerging experimental therapeutics for bipolar disorder: clues from the molecular pathophysiology. Mol. Psychiatry. 9, 734-755.
-
(2004)
Mol. Psychiatry.
, vol.9
, pp. 734-755
-
-
Quiroz, J.1
Singh, J.2
Gould, T.D.3
Denicoff, K.D.4
Zarate, C.A.5
Manji, H.K.6
-
168
-
-
0036909443
-
Regulation of Akt and glycogen synthase kinase-3beta phosphorylation by sodium valproate and lithium
-
De Sarno P., Li X., and Jope R. S. (2002) Regulation of Akt and glycogen synthase kinase-3beta phosphorylation by sodium valproate and lithium. Neuropharmacology 43, 1158-1164.
-
(2002)
Neuropharmacology
, vol.43
, pp. 1158-1164
-
-
De Sarno, P.1
Li, X.2
Jope, R.S.3
-
169
-
-
0034280096
-
Mitochondrial dysfunction in bipolar disorder
-
Kato T. and Kato N. (2000) Mitochondrial dysfunction in bipolar disorder. Bipolar Disord. 2, 180-190.
-
(2000)
Bipolar Disord.
, vol.2
, pp. 180-190
-
-
Kato, T.1
Kato, N.2
-
170
-
-
0036708175
-
Long-term lithium treatment prevents neurotoxic effects of beta-bungarotoxin in primary cultured neurons
-
Tseng W. P. and Lin-Shiau S. Y. (2002) Long-term lithium treatment prevents neurotoxic effects of beta-bungarotoxin in primary cultured neurons. J. Neurosci. Res. 69, 633-641.
-
(2002)
J. Neurosci. Res.
, vol.69
, pp. 633-641
-
-
Tseng, W.P.1
Lin-Shiau, S.Y.2
-
171
-
-
0037474040
-
Valproate inhibits oxidative damage to lipid and protein in primary cultured rat cerebrocortical cells
-
Wang J. F., Azzam J. E., and Young L. T. (2003) Valproate inhibits oxidative damage to lipid and protein in primary cultured rat cerebrocortical cells. Neuroscience 116, 485-489.
-
(2003)
Neuroscience
, vol.116
, pp. 485-489
-
-
Wang, J.F.1
Azzam, J.E.2
Young, L.T.3
-
172
-
-
0037115108
-
Correlated calcium uptake and release by mitochondria and endoplasmic reticulum of CA3 hippocampal dendrites after afferent synaptic stimulation
-
Pivovarova N. B., Pozzo-Miller L. D., Hongpaisan J., and Andrews S. B. (2002) Correlated calcium uptake and release by mitochondria and endoplasmic reticulum of CA3 hippocampal dendrites after afferent synaptic stimulation. J. Neurosci. 22, 10,653-10,661.
-
(2002)
J. Neurosci.
, vol.22
-
-
Pivovarova, N.B.1
Pozzo-Miller, L.D.2
Hongpaisan, J.3
Andrews, S.B.4
-
173
-
-
0032544637
-
Synaptic activity-dependent modulation of mitochondrial gene expression in the rat hippocampus
-
Williams J. M., Thompson V. L., Mason-Parker S. E., Abraham W. C., and Tate W. P. (1998) Synaptic activity-dependent modulation of mitochondrial gene expression in the rat hippocampus. Brain. Res. Mol. Brain Res. 60, 50-56.
-
(1998)
Brain. Res. Mol. Brain Res.
, vol.60
, pp. 50-56
-
-
Williams, J.M.1
Thompson, V.L.2
Mason-Parker, S.E.3
Abraham, W.C.4
Tate, W.P.5
-
174
-
-
0037427415
-
Mitochondrial potassium channels and uncoupling proteins in synaptic plasticity and neuronal cell death
-
Mattson M. P. and Liu D. (2003) Mitochondrial potassium channels and uncoupling proteins in synaptic plasticity and neuronal cell death. Biochem. Biophys. Res. Commun. 304, 539-549.
-
(2003)
Biochem. Biophys. Res. Commun.
, vol.304
, pp. 539-549
-
-
Mattson, M.P.1
Liu, D.2
-
175
-
-
0029845983
-
Bcl-2 potentiates the maximal calcium uptake capacity of neural cell mitochondria
-
Murphy A. N., Bredesen D. E., Cortopassi G., Wang E., and Fiskum G. (1996) Bcl-2 potentiates the maximal calcium uptake capacity of neural cell mitochondria. Proc. Natl. Acad. Sci. USA 93, 9893-9898.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 9893-9898
-
-
Murphy, A.N.1
Bredesen, D.E.2
Cortopassi, G.3
Wang, E.4
Fiskum, G.5
-
176
-
-
0034518449
-
Mitochondria and Ca(2+)in cell physiology and pathophysiology
-
Duchen M. R. (2000) Mitochondria and Ca(2+)in cell physiology and pathophysiology. Cell Calcium 28, 339-348.
-
(2000)
Cell Calcium
, vol.28
, pp. 339-348
-
-
Duchen, M.R.1
-
177
-
-
0028787686
-
Different localization of tau protein kinase I/glycogen synthase kinase-3 beta from glycogen synthase kinase-3 alpha in cerebellum mitochondria
-
Hoshi M., Sato M., Kondo S., et al. (1995) Different localization of tau protein kinase I/glycogen synthase kinase-3 beta from glycogen synthase kinase-3 alpha in cerebellum mitochondria. J. Biochem. (Tokyo) 118, 683-685.
-
(1995)
J. Biochem. (Tokyo)
, vol.118
, pp. 683-685
-
-
Hoshi, M.1
Sato, M.2
Kondo, S.3
-
178
-
-
0035900197
-
Caspase-3 activation induced by inhibition of mitochondrial complex I is facilitated by glycogen synthase kinase-3beta and attenuated by lithium
-
King T. D., Bijur G. N., and Jope R. S. (2001) Caspase-3 activation induced by inhibition of mitochondrial complex I is facilitated by glycogen synthase kinase-3beta and attenuated by lithium. Brain. Res. 919, 106-114.
-
(2001)
Brain. Res.
, vol.919
, pp. 106-114
-
-
King, T.D.1
Bijur, G.N.2
Jope, R.S.3
-
179
-
-
0037372005
-
The codon 72 polymorphic variants of p53 have markedly different apoptotic potential
-
Dumont P., Leu J. I., Della Pietra A. C. 3rd, George D. L., and Murphy M. (2003) The codon 72 polymorphic variants of p53 have markedly different apoptotic potential. Nat. Genet. 33, 357-365.
-
(2003)
Nat. Genet.
, vol.33
, pp. 357-365
-
-
Dumont, P.1
Leu, J.I.2
Della Pietra III, A.C.3
George, D.L.4
Murphy, M.5
-
180
-
-
0034717014
-
Death signal-induced localization of p53 protein to mitochondria. A potential role in apoptotic signaling
-
Marchenko N. D., Zaika A., and Moll U. M. (2000) Death signal-induced localization of p53 protein to mitochondria. A potential role in apoptotic signaling. J. Biol. Chem. 275, 16,202-16,212.
-
(2000)
J. Biol. Chem.
, vol.275
-
-
Marchenko, N.D.1
Zaika, A.2
Moll, U.M.3
-
181
-
-
0035910385
-
Hypoxia death stimulus induces translocation of p53 protein to mitochondria. Detection by immunofluorescence on whole cells
-
Sansome C., Zaika A., Marchenko N. D., and Moll U. M. (2001) Hypoxia death stimulus induces translocation of p53 protein to mitochondria. Detection by immunofluorescence on whole cells. FEBS Lett. 488, 110-115.
-
(2001)
FEBS Lett.
, vol.488
, pp. 110-115
-
-
Sansome, C.1
Zaika, A.2
Marchenko, N.D.3
Moll, U.M.4
-
182
-
-
0442274617
-
Glycogen synthase kinase-3beta (GSK3beta) binds to and promotes the actions of p53
-
Watcharasit P., Bijur G. N., Song L., Zhu J., Chen X., and Jope R. S. (2003) Glycogen synthase kinase-3beta (GSK3beta) binds to and promotes the actions of p53. J. Biol Chem. 278, 48,872-48,879.
-
(2003)
J. Biol Chem.
, vol.278
-
-
Watcharasit, P.1
Bijur, G.N.2
Song, L.3
Zhu, J.4
Chen, X.5
Jope, R.S.6
-
183
-
-
0346434149
-
Rapid accumulation of Akt in mitochondria following phosphatidylinositol 3-kinase activation
-
Bijur G. N. and Jope R. S. (2003) Rapid accumulation of Akt in mitochondria following phosphatidylinositol 3-kinase activation. J. Neurochem. 87, 1427-1435.
-
(2003)
J. Neurochem.
, vol.87
, pp. 1427-1435
-
-
Bijur, G.N.1
Jope, R.S.2
-
184
-
-
7744227096
-
Glycogen synthase kinase-3beta phosphorylates Bax and promotes its mitochondrial localization during neuronal apoptosis
-
Linseman D. A., Butts B. D., Precht T. A., et al. (2004) Glycogen synthase kinase-3beta phosphorylates Bax and promotes its mitochondrial localization during neuronal apoptosis. J. Neurosci. 24, 9993-10,002.
-
(2004)
J. Neurosci.
, vol.24
-
-
Linseman, D.A.1
Butts, B.D.2
Precht, T.A.3
-
185
-
-
18744435263
-
Lithium increases N-acetyl-aspartate in the human brain: In vivo evidence in support of bcl-2's neurotrophic effects?
-
Moore G. J., Bebchuk J. M., Hasanat K., et al. (2000) Lithium increases N-acetyl-aspartate in the human brain: in vivo evidence in support of bcl-2's neurotrophic effects? Biol. Psychiatry 48, 1-8.
-
(2000)
Biol. Psychiatry
, vol.48
, pp. 1-8
-
-
Moore, G.J.1
Bebchuk, J.M.2
Hasanat, K.3
-
186
-
-
0034619037
-
Lithium-induced increase in human brain grey matter
-
Moore G. J., Bebchuk J. M., Wilds I. B., Chen G., and Manji H. K. (2000) Lithium-induced increase in human brain grey matter. Lancet 356, 1241,1242.
-
(2000)
Lancet
, vol.356
, pp. 1241
-
-
Moore, G.J.1
Bebchuk, J.M.2
Wilds, I.B.3
Chen, G.4
Manji, H.K.5
-
187
-
-
0346034866
-
Chronic treatment with lithium, but not sodium valproate, increases cortical N-acetyl-aspartate concentrations in euthymic bipolar patients
-
Silverstone P. H., Wu R. H., O'Donnell T., Ulrich M., Asghar S. J., and Hanstock C. C. (2003) Chronic treatment with lithium, but not sodium valproate, increases cortical N-acetyl-aspartate concentrations in euthymic bipolar patients. Int. Clin. Psychopharmacol. 18, 73-79.
-
(2003)
Int. Clin. Psychopharmacol.
, vol.18
, pp. 73-79
-
-
Silverstone, P.H.1
Wu, R.H.2
O'Donnell, T.3
Ulrich, M.4
Asghar, S.J.5
Hanstock, C.C.6
-
188
-
-
0037199676
-
Increased gray matter in lithium-treated bipolar disorder patients
-
Sassi R., Nicoletti M., Brambilla P., et al. (2002) Increased gray matter in lithium-treated bipolar disorder patients. Neurosci. Lett. 329, 243.
-
(2002)
Neurosci. Lett.
, vol.329
, pp. 243
-
-
Sassi, R.1
Nicoletti, M.2
Brambilla, P.3
-
189
-
-
0030898340
-
Inositol monophosphatase inhibitors - Lithium mimetics?
-
Atack J. R. (1997) Inositol monophosphatase inhibitors - lithium mimetics? Med. Res. Rev. 17, 215-224.
-
(1997)
Med. Res. Rev.
, vol.17
, pp. 215-224
-
-
Atack, J.R.1
-
190
-
-
0027458537
-
In vitro and in vivo inhibition of inositol monophosphatase by the bisphosphonate L-690,330
-
Atack J. R., Cook S. M., Watt A. P., Fletcher S. R., and Ragan C. I. (1993) In vitro and in vivo inhibition of inositol monophosphatase by the bisphosphonate L-690,330. J. Neurochem. 60, 652-658.
-
(1993)
J. Neurochem.
, vol.60
, pp. 652-658
-
-
Atack, J.R.1
Cook, S.M.2
Watt, A.P.3
Fletcher, S.R.4
Ragan, C.I.5
-
191
-
-
0028339390
-
Effects of L-690,488, a prodrug of the bisphosphonate inositol monophosphatase inhibitor L-690,330, on phosphatidylinositol cycle markers
-
Atack J. R., Prior A. M., Fletcher S. R., Quirk K., McKernan R., and Ragan C. I. (1994) Effects of L-690,488, a prodrug of the bisphosphonate inositol monophosphatase inhibitor L-690,330, on phosphatidylinositol cycle markers. J. Pharmacol. Exp. Ther. 270, 70-76.
-
(1994)
J. Pharmacol. Exp. Ther.
, vol.270
, pp. 70-76
-
-
Atack, J.R.1
Prior, A.M.2
Fletcher, S.R.3
Quirk, K.4
McKernan, R.5
Ragan, C.I.6
-
192
-
-
0028234802
-
Mechanism of inositol monophosphatase, the putative target of lithium therapy
-
Pollack S. J., Atack J. R., Knowles M. R., et al. (1994) Mechanism of inositol monophosphatase, the putative target of lithium therapy. Proc. Natl. Acad. Sci. USA 91, 5766-5770.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 5766-5770
-
-
Pollack, S.J.1
Atack, J.R.2
Knowles, M.R.3
-
193
-
-
0026493674
-
Structure of inositol monophosphatase, the putative target of lithium therapy
-
Bone R., Springer J. P., and Atack J. R. (1992) Structure of inositol monophosphatase, the putative target of lithium therapy. Proc. Natl. Acad. Sci. USA 89, 10,031-10,035.
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
-
-
Bone, R.1
Springer, J.P.2
Atack, J.R.3
-
194
-
-
0031049691
-
Enhanced phosphorylation of the postsynaptic protein kinase C substrate RC3/neurogranin during long-term potentiation
-
Chen S. J., Sweatt J. D., and Klann E. (1997) Enhanced phosphorylation of the postsynaptic protein kinase C substrate RC3/neurogranin during long-term potentiation. Brain. Res. 749, 181-187.
-
(1997)
Brain. Res.
, vol.749
, pp. 181-187
-
-
Chen, S.J.1
Sweatt, J.D.2
Klann, E.3
-
195
-
-
0003060229
-
Protein kinase C in the nervous system
-
Kuo J. F., ed. New York: Oxford University Press
-
Conn P. J. and Sweatt J. D. (1994) Protein kinase C in the nervous system. In: Protein Kinase C, Kuo J. F., ed. New York: Oxford University Press, pp. 199-235.
-
(1994)
Protein Kinase C
, pp. 199-235
-
-
Conn, P.J.1
Sweatt, J.D.2
-
196
-
-
0036220487
-
PKC, MAP kinases and the bcl-2 family of proteins as long-term targets for mood stabilizers
-
Manji H. K. and Chen G. (2002) PKC, MAP kinases and the bcl-2 family of proteins as long-term targets for mood stabilizers. Mol. Psychiatry 7 (Suppl 1), S46-S56.
-
(2002)
Mol. Psychiatry
, vol.7
, Issue.1 SUPPL.
-
-
Manji, H.K.1
Chen, G.2
-
197
-
-
0342445420
-
A preliminary investigation of a protein kinase C inhibitor in the treatment of acute mania
-
Bebchuk J. M., Arfken C. L., Dolan-Manji S., Murphy J., Hasanat K., and Manji H. K. (2000) A preliminary investigation of a protein kinase C inhibitor in the treatment of acute mania. Arch. Gen. Psychiatry 57, 95-97.
-
(2000)
Arch. Gen. Psychiatry
, vol.57
, pp. 95-97
-
-
Bebchuk, J.M.1
Arfken, C.L.2
Dolan-Manji, S.3
Murphy, J.4
Hasanat, K.5
Manji, H.K.6
-
198
-
-
0022892593
-
Inhibition of protein kinase C mediated signal transduction by tamoxifen. Importance for antitumour activity
-
Horgan K., Cooke E., Hallett M. B., and Mansel R. E. (1986) Inhibition of protein kinase C mediated signal transduction by tamoxifen. Importance for antitumour activity. Biochem. Pharmacol. 35, 4463-4465.
-
(1986)
Biochem. Pharmacol.
, vol.35
, pp. 4463-4465
-
-
Horgan, K.1
Cooke, E.2
Hallett, M.B.3
Mansel, R.E.4
-
199
-
-
0023764676
-
Specific and direct binding of protein kinase C to an immobilized tamoxifen analogue
-
O'Brian C. A., Housey G. M., and Weinstein I. B. (1988) Specific and direct binding of protein kinase C to an immobilized tamoxifen analogue. Cancer Res. 48, 3626-3629.
-
(1988)
Cancer Res.
, vol.48
, pp. 3626-3629
-
-
O'Brian, C.A.1
Housey, G.M.2
Weinstein, I.B.3
-
200
-
-
0036247969
-
Potential new medical therapies for diabetic retinopathy: Protein kinase C inhibitors
-
Frank R. N. (2002) Potential new medical therapies for diabetic retinopathy: protein kinase C inhibitors. Am. J. Ophthalmol. 133, 693-698.
-
(2002)
Am. J. Ophthalmol.
, vol.133
, pp. 693-698
-
-
Frank, R.N.1
-
201
-
-
0037293351
-
Ruboxistaurin (Eli Lilly)
-
Wheeler G. D. (2003) Ruboxistaurin (Eli Lilly). IDrugs 6, 159-163.
-
(2003)
IDrugs
, vol.6
, pp. 159-163
-
-
Wheeler, G.D.1
-
202
-
-
0036939182
-
The potential role of PKC beta in diabetic retinopathy and macular edema
-
Aiello L. P. (2002) The potential role of PKC beta in diabetic retinopathy and macular edema. Surv. Ophthalmol. 47 (Suppl 2), S263-S269.
-
(2002)
Surv. Ophthalmol.
, vol.47
, Issue.2 SUPPL.
-
-
Aiello, L.P.1
-
203
-
-
0032987224
-
Inhibition of protein kinase C - Do we, can we, and should we?
-
Parker P. J. (1999) Inhibition of protein kinase C - do we, can we, and should we? Pharmacol. Ther. 82, 263-267.
-
(1999)
Pharmacol. Ther.
, vol.82
, pp. 263-267
-
-
Parker, P.J.1
-
204
-
-
0036398986
-
The role of glycogen synthase kinase-3 in insulin resistance and Type 2 diabetes
-
Kaidanovich O. and Eldar-Finkelman H. (2002) The role of glycogen synthase kinase-3 in insulin resistance and Type 2 diabetes. Expert Opin. Ther. Targets 6, 555-561.
-
(2002)
Expert Opin. Ther. Targets
, vol.6
, pp. 555-561
-
-
Kaidanovich, O.1
Eldar-Finkelman, H.2
-
205
-
-
0036769733
-
GSK3beta signalling: Casting a wide net in Alzheimer's disease
-
Bhat R. V. and Budd S. L. (2002) GSK3beta signalling: casting a wide net in Alzheimer's disease. Neurosignals 11, 251-261.
-
(2002)
Neurosignals
, vol.11
, pp. 251-261
-
-
Bhat, R.V.1
Budd, S.L.2
-
206
-
-
0036276050
-
Regulation of tau phosphorylation and protection against beta-amyloid-induced neurodegeneration by lithium. Possible implications for Alzheimer's disease
-
Alvarez G., Munoz-Montano J. R., Satrustegui J., Avila J., Bogonez E., and Diaz-Nido J. (2002) Regulation of tau phosphorylation and protection against beta-amyloid-induced neurodegeneration by lithium. Possible implications for Alzheimer's disease. Bipolar Disord. 4, 153-165.
-
(2002)
Bipolar Disord.
, vol.4
, pp. 153-165
-
-
Alvarez, G.1
Munoz-Montano, J.R.2
Satrustegui, J.3
Avila, J.4
Bogonez, E.5
Diaz-Nido, J.6
-
207
-
-
0037087220
-
Lithium inhibits amyloid secretion in COS7 cells transfected with amyloid precursor protein C100
-
Sun X., Sato S., Murayama O., et al. (2002) Lithium inhibits amyloid secretion in COS7 cells transfected with amyloid precursor protein C100. Neurosci. Lett. 321, 61-64.
-
(2002)
Neurosci. Lett.
, vol.321
, pp. 61-64
-
-
Sun, X.1
Sato, S.2
Murayama, O.3
-
208
-
-
0037040856
-
Phosphorylation of glycogen synthase kinase-3beta during preconditioning through a phosphatidylinositol-3-kinase - Dependent pathway is cardioprotective
-
Tong H., Imahashi K., Steenbergen C., and Murphy E. (2002) Phosphorylation of glycogen synthase kinase-3beta during preconditioning through a phosphatidylinositol-3-kinase - dependent pathway is cardioprotective. Circ. Res. 90, 377-379.
-
(2002)
Circ. Res.
, vol.90
, pp. 377-379
-
-
Tong, H.1
Imahashi, K.2
Steenbergen, C.3
Murphy, E.4
-
209
-
-
0035477020
-
GSK3 takes centre stage more than 20 years after its discovery
-
Frame S. and Cohen P. (2001) GSK3 takes centre stage more than 20 years after its discovery. Biochem. J. 359, 1-16.
-
(2001)
Biochem. J.
, vol.359
, pp. 1-16
-
-
Frame, S.1
Cohen, P.2
-
210
-
-
0034870853
-
Different expression of glycogen synthase kinase-3beta between young and old rat brains after transient middle cerebral artery occlusion
-
Sasaki C., Hayashi T., Zhang W. R., et al. (2001) Different expression of glycogen synthase kinase-3beta between young and old rat brains after transient middle cerebral artery occlusion. Neurol. Res. 23, 588-592.
-
(2001)
Neurol. Res.
, vol.23
, pp. 588-592
-
-
Sasaki, C.1
Hayashi, T.2
Zhang, W.R.3
-
211
-
-
0036799220
-
Inhibitors of glycogen synthase kinase-3: Future therapy for unmet medical needs
-
Dorronsoro I., Castro A., and Martinez A. (2002) Inhibitors of glycogen synthase kinase-3: future therapy for unmet medical needs. Expert Opin. Ther. Patents 12, 1527-1536.
-
(2002)
Expert Opin. Ther. Patents
, vol.12
, pp. 1527-1536
-
-
Dorronsoro, I.1
Castro, A.2
Martinez, A.3
-
212
-
-
0037075791
-
First non-ATP competitive glycogen synthase kinase 3 beta (GSK-3beta) inhibitors: Thiadiazolidinones (TDZD) as potential drugs for the treatment of Alzheimer's disease
-
Martinez A., Alonso M., Castro A., Perez C., and Moreno F. J. (2002) First non-ATP competitive glycogen synthase kinase 3 beta (GSK-3beta) inhibitors: thiadiazolidinones (TDZD) as potential drugs for the treatment of Alzheimer's disease. J. Med. Chem. 45, 1292-1299.
-
(2002)
J. Med. Chem.
, vol.45
, pp. 1292-1299
-
-
Martinez, A.1
Alonso, M.2
Castro, A.3
Perez, C.4
Moreno, F.J.5
-
213
-
-
0038811796
-
Insulin mimetic action of synthetic phosphorylated Peptide inhibitors of glycogen synthase kinase-3
-
Plotkin B., Kaidanovich O., Talior I., and Eldar-Finkelman H. (2003) Insulin mimetic action of synthetic phosphorylated Peptide inhibitors of glycogen synthase kinase-3. J. Pharmacol. Exp. Ther. 305, 974-980.
-
(2003)
J. Pharmacol. Exp. Ther.
, vol.305
, pp. 974-980
-
-
Plotkin, B.1
Kaidanovich, O.2
Talior, I.3
Eldar-Finkelman, H.4
-
214
-
-
0036273020
-
Glycogen synthase kinase 3 (GSK-3) inhibitors as new promising drugs for diabetes, neurodegeneration, cancer, and inflammation
-
Martinez A., Castro A., Dorronsoro I., and Alonso M. (2002) Glycogen synthase kinase 3 (GSK-3) inhibitors as new promising drugs for diabetes, neurodegeneration, cancer, and inflammation. Med. Res. Rev. 22, 373-384.
-
(2002)
Med. Res. Rev.
, vol.22
, pp. 373-384
-
-
Martinez, A.1
Castro, A.2
Dorronsoro, I.3
Alonso, M.4
-
216
-
-
0036302005
-
Inhibition of glycogen synthase kinase-3beta by bivalent zinc ions: Insight into the insulin-mimetic action of zinc
-
Ilouz R., Kaidanovich O., Gurwitz D., and Eldar-Finkelman H. (2002) Inhibition of glycogen synthase kinase-3beta by bivalent zinc ions: insight into the insulin-mimetic action of zinc. Biochem. Biophys. Res. Commun. 295, 102-106.
-
(2002)
Biochem. Biophys. Res. Commun.
, vol.295
, pp. 102-106
-
-
Ilouz, R.1
Kaidanovich, O.2
Gurwitz, D.3
Eldar-Finkelman, H.4
-
217
-
-
0036272279
-
Antidepressants and neuroplasticity
-
D'Sa C. and Duman R. (2002) Antidepressants and neuroplasticity. Bipolar Disorder 4, 183.
-
(2002)
Bipolar Disorder
, vol.4
, pp. 183
-
-
D'Sa, C.1
Duman, R.2
-
218
-
-
0038147541
-
Enhancing neuronal plasticity and cellular resilience to develop novel, improved therapeutics for difficult-to-treat depression
-
Manji H. K., Quiroz J. A., Sporn J., et al. (2003) Enhancing neuronal plasticity and cellular resilience to develop novel, improved therapeutics for difficult-to-treat depression. Biol. Psychiatry 53, 707-742.
-
(2003)
Biol. Psychiatry
, vol.53
, pp. 707-742
-
-
Manji, H.K.1
Quiroz, J.A.2
Sporn, J.3
-
219
-
-
0021720605
-
Results of a phase II study of the antidepressant effect of rolipram
-
Zeller E., Stief H. J., Pflug B., and Sastre-y-Hernandez M. (1984) Results of a phase II study of the antidepressant effect of rolipram. Pharmacopsychiatry 17, 188-190.
-
(1984)
Pharmacopsychiatry
, vol.17
, pp. 188-190
-
-
Zeller, E.1
Stief, H.J.2
Pflug, B.3
Sastre-y-Hernandez, M.4
-
220
-
-
0024269472
-
Is phosphodiesterase inhibition a new mechanism of antidepressant action? A double blind double-dummy study between rolipram and desipramine in hospitalized major and/or endogenous depressives
-
Bobon D., Breulet M., Gerard-Vandenhove M. A., et al. (1988) Is phosphodiesterase inhibition a new mechanism of antidepressant action? A double blind double-dummy study between rolipram and desipramine in hospitalized major and/or endogenous depressives. Eur. Arch. Psychiatry. Neurol. Sci. 238, 2-6.
-
(1988)
Eur. Arch. Psychiatry. Neurol. Sci.
, vol.238
, pp. 2-6
-
-
Bobon, D.1
Breulet, M.2
Gerard-Vandenhove, M.A.3
-
221
-
-
0024319477
-
Rolipram in major depressive disorder: Results of a double-blind comparative study with imipramine
-
Hebenstreit G. F., Fellerer K., Fichte K., et al. (1989) Rolipram in major depressive disorder: results of a double-blind comparative study with imipramine. Pharmacopsychiatry 22, 156-160.
-
(1989)
Pharmacopsychiatry
, vol.22
, pp. 156-160
-
-
Hebenstreit, G.F.1
Fellerer, K.2
Fichte, K.3
-
222
-
-
0035727846
-
The antidepressant and antiinflammatory effects of rolipram in the central nervous system
-
Zhu J., Mix E., and Winblad B. (2001) The antidepressant and antiinflammatory effects of rolipram in the central nervous system. CNS Drug. Rev. 7, 387-398.
-
(2001)
CNS Drug. Rev.
, vol.7
, pp. 387-398
-
-
Zhu, J.1
Mix, E.2
Winblad, B.3
-
223
-
-
0035755974
-
Histone deacetylases and cancer: Causes and therapies
-
Marks P., Rifkind R. A., Richon V. M., Breslow R., Miller T., and Kelly W. K. (2001) Histone deacetylases and cancer: causes and therapies. Nat. Rev. Cancer. 1, 194-202.
-
(2001)
Nat. Rev. Cancer.
, vol.1
, pp. 194-202
-
-
Marks, P.1
Rifkind, R.A.2
Richon, V.M.3
Breslow, R.4
Miller, T.5
Kelly, W.K.6
-
224
-
-
0037237645
-
The emerging differential roles of GABAergic and antiglutamatergic agents in bipolar disorders
-
Ketter T. A. and Wang P. W. (2003) The emerging differential roles of GABAergic and antiglutamatergic agents in bipolar disorders. J. Clin. Psychiatry 64(Suppl 3), 15-20.
-
(2003)
J. Clin. Psychiatry
, vol.64
, Issue.3 SUPPL.
, pp. 15-20
-
-
Ketter, T.A.1
Wang, P.W.2
-
225
-
-
0031807854
-
Psychoneuroendocrinology of depression. Hypothalamic-pituitary-adrenal axis
-
Plotsky P. M., Owens M. J., and Nemeroff C. B. (1998) Psychoneuroendocrinology of depression. Hypothalamic-pituitary-adrenal axis. Psychiatr. Clin. North. Am. 21, 293-307.
-
(1998)
Psychiatr. Clin. North. Am.
, vol.21
, pp. 293-307
-
-
Plotsky, P.M.1
Owens, M.J.2
Nemeroff, C.B.3
-
226
-
-
0036212671
-
Organization of the stress system and its dysregulation in melancholic and atypical depression: High vs low CRH/NE states
-
Gold P. W. and Chrousos G. P. (2002) Organization of the stress system and its dysregulation in melancholic and atypical depression: high vs low CRH/NE states. Mol. Psychiatry 7, 254-275.
-
(2002)
Mol. Psychiatry
, vol.7
, pp. 254-275
-
-
Gold, P.W.1
Chrousos, G.P.2
-
227
-
-
0037359880
-
The pharmacology of CP-154,526, a non-peptide antagonist of the CRH1 receptor: A review
-
Seymour P. A., Schmidt A. W., and Schulz D. W. (2003) The pharmacology of CP-154,526, a non-peptide antagonist of the CRH1 receptor: a review. CNS Drug Rev. 9, 57-96.
-
(2003)
CNS Drug Rev.
, vol.9
, pp. 57-96
-
-
Seymour, P.A.1
Schmidt, A.W.2
Schulz, D.W.3
-
228
-
-
0030964813
-
Antidepressant-like effects of CP-154,526, a selective CRF1 receptor antagonist
-
Mansbach R. S., Brooks E. N., and Chen Y. L. (1997) Antidepressant-like effects of CP-154,526, a selective CRF1 receptor antagonist. Eur. J. Pharmacol. 323, 21-26.
-
(1997)
Eur. J. Pharmacol.
, vol.323
, pp. 21-26
-
-
Mansbach, R.S.1
Brooks, E.N.2
Chen, Y.L.3
-
229
-
-
12244304183
-
A non-steroidal glucocorticoid receptor antagonist
-
Miner J. N., Tyree C., Hu J., et al. (2003) A non-steroidal glucocorticoid receptor antagonist. Mol. Endocrinol. 17, 117-127.
-
(2003)
Mol. Endocrinol.
, vol.17
, pp. 117-127
-
-
Miner, J.N.1
Tyree, C.2
Hu, J.3
-
230
-
-
0038745558
-
Glucocorticoid receptor antagonism by cyproterone acetate and RU486
-
Honer C., Nam K., Fink C., et al. (2003) Glucocorticoid receptor antagonism by cyproterone acetate and RU486. Mol. Pharmacol. 63, 1012-1020.
-
(2003)
Mol. Pharmacol.
, vol.63
, pp. 1012-1020
-
-
Honer, C.1
Nam, K.2
Fink, C.3
-
231
-
-
0026536597
-
Mania in association with hydrocortisone replacement for Addison's disease
-
Ur E., Turner T. H., Goodwill T. J., Grossman A., and Besser G. M. (1992) Mania in association with hydrocortisone replacement for Addison's disease. Postgrad. Med. J. 68, 41-43.
-
(1992)
Postgrad. Med. J.
, vol.68
, pp. 41-43
-
-
Ur, E.1
Turner, T.H.2
Goodwill, T.J.3
Grossman, A.4
Besser, G.M.5
-
232
-
-
0036182519
-
The influence of hormones and pharmaceutical agents on DHEA and DHEA-S concentrations: A review of clinical studies
-
Salek F. S., Bigos K. L., and Kroboth P. D. (2002) The influence of hormones and pharmaceutical agents on DHEA and DHEA-S concentrations: a review of clinical studies. J. Clin. Pharmacol. 42, 247-266.
-
(2002)
J. Clin. Pharmacol.
, vol.42
, pp. 247-266
-
-
Salek, F.S.1
Bigos, K.L.2
Kroboth, P.D.3
-
233
-
-
0042126365
-
Modulators of the glutamatergic system: Implications for the development of improved therapeutics in mood disorders
-
Zarate C. A., Quiroz J., Payne J., and Manji H. K. (2002) Modulators of the glutamatergic system: implications for the development of improved therapeutics in mood disorders. Psychopharmacol. Bull. 36, 35-83.
-
(2002)
Psychopharmacol. Bull.
, vol.36
, pp. 35-83
-
-
Zarate, C.A.1
Quiroz, J.2
Payne, J.3
Manji, H.K.4
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