Antidepressants alter cell proliferation in the adult brain in vivo and in neural cultures in vitro

European Journal of Pharmacology

Volumn 411, Issue 1-2, 2001, Pages 67-70

  Manev, Hari ^a   Uz, Tolga ^a   Smalheiser, Neil R ^a   Manev, Radmila ^a  

^a UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

Author keywords

Antidepressant; Cerebellar granule; Fluoxetine; Hippocampus; Neurogenesis

Indexed keywords

ANTIDEPRESSANT AGENT; BROXURIDINE; CLOMIPRAMINE; DESIPRAMINE; FLUOXETINE; THYMIDINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL PROLIFERATION; CEREBELLUM; CONTROLLED STUDY; DENTATE GYRUS; DRUG MECHANISM; GRANULE CELL; HIPPOCAMPUS; NERVE CELL CULTURE; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; ANTIDEPRESSIVE AGENTS; BRAIN; CELL DIVISION; CELLS, CULTURED; CEREBELLUM; CLOMIPRAMINE; DESIPRAMINE; DOSE-RESPONSE RELATIONSHIP, DRUG; FLUOXETINE; IMIPRAMINE; NERVOUS SYSTEM; RATS; RATS, INBRED BN; RATS, SPRAGUE-DAWLEY; THYMIDINE;

EID: 0035179732     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(00)00904-3     Document Type: Article

References (14)

1. Peripheral infusion of IGF-I selectively induces neurogenesis in the adult rat hippocampus
2. Potassium chloride inhibits proliferation of cerebellar granule neuron progenitors
3. Differential effects of chronic antidepressant treatment on swim stress- and fluoxetine-induced secretion of corticosterone and progesterone
4. Role of protein kinase C and cAMP in fluoxetine effects on human T-cell proliferation
5. Opiates inhibit neurogenesis in the adult rat hippocampus
6. GABA induces proliferation of immature cerebellar granule cells grown in vitro
7. Differential effects of fluoxetine on murine B-cell proliferation depending on the biochemical pathways triggered by distinct mitogens
8. Opioids intrinsically inhibit the genesis of mouse cerebellar granule neuron precursors in vitro: Differential impact of mu and delta receptor activation on proliferation and neurite elongation
9. Chronic fluoxetine treatment increases hippocampal neurogenesis in rats: A novel theory of depression
10. Serotonin stimulates the production of new hippocampal granule neurons via the 5-HT 1A receptor in the adult rat
11. Adult brain neurogenesis and psychiatry: A novel theory of depression
12. Chronic antidepressant administration increases granule cell genesis in the hippocampus of the adult male rat
13. Primary cultures of rat cerebellar granule cells as a model to study neuronal 5-lipoxygenase and FLAP gene expression
14. Delayed increase of calcium influx elicited by glutamate: Role in neuronal death