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Volumn 46, Issue 10, 1999, Pages 1328-1351

Protein kinase C signaling in the brain: Molecular transduction of mood stabilization in the treatment of manic-depressive illness

Author keywords

AP 1; Lithium; Manic depressive; MARCKS; Protein kinase C; Valproate

Indexed keywords

ANTIESTROGEN; CARBAMAZEPINE; CYTIDINE PHOSPHATE; DIAZEPAM; FLUOXETINE; HALOPERIDOL; IMIPRAMINE; LITHIUM; LITHIUM CHLORIDE; MARCKS PROTEIN; MORPHINE; PHENYTOIN; PHOSPHATIDIC ACID; PHOSPHATIDYLINOSITIDE; PROTEIN KINASE C; PROTEIN KINASE INHIBITOR; TAMOXIFEN; TRANSCRIPTION FACTOR AP 1; VALPROIC ACID; VERAPAMIL; ENZYME ACTIVATOR; GLYCOGEN SYNTHASE KINASE 3; PROTEIN KINASE (CALCIUM,CALMODULIN); TRANQUILIZER;

EID: 0033570745     PISSN: 00063223     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-3223(99)00235-8     Document Type: Review
Times cited : (242)

References (192)
  • 1
    • 0026472164 scopus 로고
    • The MARCKS brothers: A family of protein kinase C substrates
    • Aderem A. The MARCKS brothers A family of protein kinase C substrates . Cell. 71:1992;713-716.
    • (1992) Cell , vol.71 , pp. 713-716
    • Aderem, A.1
  • 2
    • 0028893706 scopus 로고
    • Excess cardiovascular and suicide mortality of affective disorders may be reduced by lithium prophylaxis
    • Ahrens B., Muller-Oerlinghausen B., Schou M., et al. Excess cardiovascular and suicide mortality of affective disorders may be reduced by lithium prophylaxis. J Affective Disord. 33:1995;67-75.
    • (1995) J Affective Disord , vol.33 , pp. 67-75
    • Ahrens, B.1    Muller-Oerlinghausen, B.2    Schou, M.3
  • 3
    • 0015242494 scopus 로고
    • Reduced brain inositol in lithium treated rats
    • Allison J.H., Stewart M.A. Reduced brain inositol in lithium treated rats. Nature. 233:1971;267-268.
    • (1971) Nature , vol.233 , pp. 267-268
    • Allison, J.H.1    Stewart, M.A.2
  • 4
    • 0032456140 scopus 로고    scopus 로고
    • Acute regulation of norepinephrine transport: II. PKC-modulated surface expression of human norepinephrine transporter proteins
    • Apparsundaram S., Schroeter S., Giovanetti E., Blakely R.D. Acute regulation of norepinephrine transport II. PKC-modulated surface expression of human norepinephrine transporter proteins . J Pharmacol Exp Ther. 287:1998;744-751.
    • (1998) J Pharmacol Exp Ther , vol.287 , pp. 744-751
    • Apparsundaram, S.1    Schroeter, S.2    Giovanetti, E.3    Blakely, R.D.4
  • 5
    • 0027268059 scopus 로고
    • Characterization of the effects of lithium on phosphatidylinositol (PI) cycle activity in human muscarinic m1 receptor-transfected CHO cells
    • Atack J.R., Prior A.M., Griffith D., Ragan C.I. Characterization of the effects of lithium on phosphatidylinositol (PI) cycle activity in human muscarinic m1 receptor-transfected CHO cells. Br J Pharmacol. 110:1993;809-815.
    • (1993) Br J Pharmacol , vol.110 , pp. 809-815
    • Atack, J.R.1    Prior, A.M.2    Griffith, D.3    Ragan, C.I.4
  • 6
    • 0030910613 scopus 로고    scopus 로고
    • Increased phosphorylation of myelin basic protein during hippocampal long-term potentiation
    • Atkins C.M., Chen S.J., Klann E., Sweatt J.D. Increased phosphorylation of myelin basic protein during hippocampal long-term potentiation. J Neurochem. 68:1997;1960-1967.
    • (1997) J Neurochem , vol.68 , pp. 1960-1967
    • Atkins, C.M.1    Chen, S.J.2    Klann, E.3    Sweatt, J.D.4
  • 7
    • 0029845056 scopus 로고    scopus 로고
    • Effects of the rate of discontinuing lithium maintenance treatment in bipolar disorders
    • Baldessarini R.J., Tondo L., Faedda G.L., et al. Effects of the rate of discontinuing lithium maintenance treatment in bipolar disorders. J Clin Psychiatry. 57:1996;441-448.
    • (1996) J Clin Psychiatry , vol.57 , pp. 441-448
    • Baldessarini, R.J.1    Tondo, L.2    Faedda, G.L.3
  • 8
    • 0024418268 scopus 로고
    • Second messenger systems and psychoactive drug focus on the phosphoinositide system and lithium
    • Baraban J.M., Worley P.F., Synder S.H. Second messenger systems and psychoactive drug focus on the phosphoinositide system and lithium. Am J Psychiatry. 146:1989;1251-1260.
    • (1989) Am J Psychiatry , vol.146 , pp. 1251-1260
    • Baraban, J.M.1    Worley, P.F.2    Synder, S.H.3
  • 10
    • 0025989384 scopus 로고
    • Preferential release of catecholamine from permeabilized PC12 cells by α and β type protein kinase C subspecies
    • Ben-Schlomo H., Sigmund O., Stabel S., Reiss N., Naor Z. Preferential release of catecholamine from permeabilized PC12 cells by α and β type protein kinase C subspecies. Biochem J. 280:1991;65-69.
    • (1991) Biochem J , vol.280 , pp. 65-69
    • Ben-Schlomo, H.1    Sigmund, O.2    Stabel, S.3    Reiss, N.4    Naor, Z.5
  • 11
    • 0020465411 scopus 로고
    • Lithium amplifies agonist-dependent phosphatidylinositol responses in brain and salivary glands
    • Berridge M.J., Downes C.P., Hanley M.R. Lithium amplifies agonist-dependent phosphatidylinositol responses in brain and salivary glands. Biochem J. 206:1982;587-595.
    • (1982) Biochem J , vol.206 , pp. 587-595
    • Berridge, M.J.1    Downes, C.P.2    Hanley, M.R.3
  • 12
    • 0024341795 scopus 로고
    • Neural and developmental actions of lithium: A unifying hypothesis
    • Berridge M.J., Downes C.P., Hanley M.R. Neural and developmental actions of lithium A unifying hypothesis . Cell. 59:1989;411-419.
    • (1989) Cell , vol.59 , pp. 411-419
    • Berridge, M.J.1    Downes, C.P.2    Hanley, M.R.3
  • 13
    • 0028310794 scopus 로고
    • Visualization of agonist-stimulated inositol phospholipid turnover in individual neurons of the rat cerebral cortex and hippocampus
    • Bevilacqua J.A., Downes C.P., Lowenstein P.R. Visualization of agonist-stimulated inositol phospholipid turnover in individual neurons of the rat cerebral cortex and hippocampus. Neuroscience. 60:1994;945-958.
    • (1994) Neuroscience , vol.60 , pp. 945-958
    • Bevilacqua, J.A.1    Downes, C.P.2    Lowenstein, P.R.3
  • 14
    • 0025356574 scopus 로고
    • The regulation and cellular functions of phosphatidylcholine hydrolysis
    • Billah M.M., Anthes J.C. The regulation and cellular functions of phosphatidylcholine hydrolysis. Biochem J. 269:1990;281-291.
    • (1990) Biochem J , vol.269 , pp. 281-291
    • Billah, M.M.1    Anthes, J.C.2
  • 15
    • 0027392102 scopus 로고
    • The MARCKS family of cellular protein kinase C substrates
    • Blackshear P.J. The MARCKS family of cellular protein kinase C substrates. J Biol Chem. 268:1993;1501-1504.
    • (1993) J Biol Chem , vol.268 , pp. 1501-1504
    • Blackshear, P.J.1
  • 17
    • 0028241634 scopus 로고
    • Peroxisomal proliferators inhibit acyl CoA synthetase and stimulate protein kinase C in vivo
    • Bojes H.K., Thurman R.G. Peroxisomal proliferators inhibit acyl CoA synthetase and stimulate protein kinase C in vivo. Toxicol Appl Pharmacol. 126:1994;233-239.
    • (1994) Toxicol Appl Pharmacol , vol.126 , pp. 233-239
    • Bojes, H.K.1    Thurman, R.G.2
  • 18
    • 0026708132 scopus 로고
    • Expression of four protein kinase C isoforms in rat fibroblasts. Distinct subcellular distribution and regulation by calcium and phorbol esters
    • Borner C., Guadagno S.N., Fabbro D., Weinstein I. Expression of four protein kinase C isoforms in rat fibroblasts. Distinct subcellular distribution and regulation by calcium and phorbol esters. J Bio Chem. 267:1992;12892-12899.
    • (1992) J Bio Chem , vol.267 , pp. 12892-12899
    • Borner, C.1    Guadagno, S.N.2    Fabbro, D.3    Weinstein, I.4
  • 19
    • 0027351998 scopus 로고
    • Molecular machines integrate coincident synaptic signals
    • Bourne HR, Nicoll R (1993): Molecular machines integrate coincident synaptic signals. Cell 72(suppl):65-75.
    • (1993) Cell , vol.72 , Issue.SUPPL. , pp. 65-75
    • Bourne, H.R.1    Nicoll, R.2
  • 20
    • 0043194187 scopus 로고    scopus 로고
    • Valproate in mania
    • (in press) In: Manji HK, Bowden CL, Belmaker RH, editors Washington, DC: American Psychiatric Press
    • Bowden CL (in press): Valproate in mania. In: Manji HK, Bowden CL, Belmaker RH, editors. Bipolar Medications: Mechanisms of Action. Washington, DC: American Psychiatric Press.
    • Bipolar Medications: Mechanisms of Action
    • Bowden, C.L.1
  • 21
    • 0028281080 scopus 로고
    • Efficacy of divalproex vs. lithium and placebo in the treatment of mania
    • Bowden C.L., Brugger A.M., Swann A.C., et al. Efficacy of divalproex vs. lithium and placebo in the treatment of mania. JAMA. 271:1994;918-924.
    • (1994) JAMA , vol.271 , pp. 918-924
    • Bowden, C.L.1    Brugger, A.M.2    Swann, A.C.3
  • 22
    • 0026029808 scopus 로고
    • Activation of protein kinase C decreases phosphorylation of c-Jun at sites that negatively regulate its DNA-binding activity
    • Boyle W.J., Smeal T., Defize L.H., Angel P., Woodgett J.R., Karin M., Hunter T. Activation of protein kinase C decreases phosphorylation of c-Jun at sites that negatively regulate its DNA-binding activity. Cell. 64:1991;573-584.
    • (1991) Cell , vol.64 , pp. 573-584
    • Boyle, W.J.1    Smeal, T.2    Defize, L.H.3    Angel, P.4    Woodgett, J.R.5    Karin, M.6    Hunter, T.7
  • 23
    • 0026092733 scopus 로고
    • Influence of lithium on second messenger accumulation in NG108-15 cells
    • Brami B.A., Leli U., Hauser G. Influence of lithium on second messenger accumulation in NG108-15 cells. Biochem Biophys Res Commun. 174:1991;606-612.
    • (1991) Biochem Biophys Res Commun , vol.174 , pp. 606-612
    • Brami, B.A.1    Leli, U.2    Hauser, G.3
  • 24
    • 0027510506 scopus 로고
    • Elevated phosphatidyl-CMP is not the source of diacylglycerol accumulation induced by lithium in NG108-15 cells
    • Brami B.A., Leli U., Hauser G. Elevated phosphatidyl-CMP is not the source of diacylglycerol accumulation induced by lithium in NG108-15 cells. J Neurochem. 60:1993;1137-1142.
    • (1993) J Neurochem , vol.60 , pp. 1137-1142
    • Brami, B.A.1    Leli, U.2    Hauser, G.3
  • 25
    • 0025907561 scopus 로고
    • Effects of chronic lithium treatment on protein kinase C and cyclic AMP-dependent protein phosphorylation
    • Casebolt T.L., Jope R.S. Effects of chronic lithium treatment on protein kinase C and cyclic AMP-dependent protein phosphorylation. Biol Psychiatry. 29:1991;233-243.
    • (1991) Biol Psychiatry , vol.29 , pp. 233-243
    • Casebolt, T.L.1    Jope, R.S.2
  • 26
    • 0024319364 scopus 로고
    • Phosphoinositide metabolism and hormone action
    • Catt K.J., Balla T. Phosphoinositide metabolism and hormone action. Annu Rev Med. 40:1989;487-509.
    • (1989) Annu Rev Med , vol.40 , pp. 487-509
    • Catt, K.J.1    Balla, T.2
  • 28
    • 0029848644 scopus 로고    scopus 로고
    • Attenuation of adenylyl cyclases by carbamazepine in vitro
    • Chen G., Hawver D., Wright C., Potter W.Z., Manji H.K. Attenuation of adenylyl cyclases by carbamazepine in vitro. J Neurochem. 67:1996;2079-2086.
    • (1996) J Neurochem , vol.67 , pp. 2079-2086
    • Chen, G.1    Hawver, D.2    Wright, C.3    Potter, W.Z.4    Manji, H.K.5
  • 29
    • 0033014180 scopus 로고    scopus 로고
    • The mood stabilizing agent Valproate inhibits the activity of Glycogen Synthase Kinase 3
    • Chen G., Huang L.D., Jiang Y., Manji H.K. The mood stabilizing agent Valproate inhibits the activity of Glycogen Synthase Kinase 3. J Neurochem. 72:1999;1327-1330.
    • (1999) J Neurochem , vol.72 , pp. 1327-1330
    • Chen, G.1    Huang, L.D.2    Jiang, Y.3    Manji, H.K.4
  • 30
    • 0027944371 scopus 로고
    • Chronic sodium valproate selectively decreases protein kinase C α and ε in vitro
    • Chen G., Manji H.K., Hawver D.B., et al. Chronic sodium valproate selectively decreases protein kinase C α and ε in vitro. J Neurochem. 63:1994;2361-2364.
    • (1994) J Neurochem , vol.63 , pp. 2361-2364
    • Chen, G.1    Manji, H.K.2    Hawver, D.B.3
  • 31
    • 0031105918 scopus 로고    scopus 로고
    • Increase in AP-1 transcription factor DNA binding activity by valproic acid
    • Chen G., Yuan P., Hawver D., Potter W.Z., Manji H.K. Increase in AP-1 transcription factor DNA binding activity by valproic acid. Neuropsychopharmacology. 16:1997;238-245.
    • (1997) Neuropsychopharmacology , vol.16 , pp. 238-245
    • Chen, G.1    Yuan, P.2    Hawver, D.3    Potter, W.Z.4    Manji, H.K.5
  • 32
    • 0031930118 scopus 로고    scopus 로고
    • Lithium increases tyrosine hydroxylase levels both in vivo and in vitro
    • Chen G., Yuan P.X., Jiang Y., Huang L.D., Manji H.K. Lithium increases tyrosine hydroxylase levels both in vivo and in vitro. J Neurochem. 70:1998;1768-1771.
    • (1998) J Neurochem , vol.70 , pp. 1768-1771
    • Chen, G.1    Yuan, P.X.2    Jiang, Y.3    Huang, L.D.4    Manji, H.K.5
  • 34
    • 0032956630 scopus 로고    scopus 로고
    • The mood-stabilizing agents lithium and valproate robustly increase the levels of the neuroprotective protein bcl-2 in the CNS
    • Chen G., Zeng W., Yuan P., Huang L., Manji H.K. The mood-stabilizing agents lithium and valproate robustly increase the levels of the neuroprotective protein bcl-2 in the CNS. J Neurochem. 72:1999;879-882.
    • (1999) J Neurochem , vol.72 , pp. 879-882
    • Chen, G.1    Zeng, W.2    Yuan, P.3    Huang, L.4    Manji, H.K.5
  • 35
    • 0032519653 scopus 로고    scopus 로고
    • Inhibition of the membrane translocation and activation of protein kinase C, and potentiation of doxorubicin-induced apoptosis of hepatocellular carcinoma cells by tamoxifen
    • Cheng A.L., Chuang S.E., Fine R.L., Yeh K.H., Liao C.M., Lay J.D., Chen D.S. Inhibition of the membrane translocation and activation of protein kinase C, and potentiation of doxorubicin-induced apoptosis of hepatocellular carcinoma cells by tamoxifen. Biochem Pharmacol. 55:1998;523-531.
    • (1998) Biochem Pharmacol , vol.55 , pp. 523-531
    • Cheng, A.L.1    Chuang, S.E.2    Fine, R.L.3    Yeh, K.H.4    Liao, C.M.5    Lay, J.D.6    Chen, D.S.7
  • 36
    • 0026031035 scopus 로고
    • Recent advances in treatment of acute mania
    • Chou J.C. Recent advances in treatment of acute mania. J Clin Psychopharmacol. 11:1991;3-21.
    • (1991) J Clin Psychopharmacol , vol.11 , pp. 3-21
    • Chou, J.C.1
  • 37
    • 0024513997 scopus 로고
    • Neurotransmitter receptors and phosphoinositide turnover
    • Chuang D.M. Neurotransmitter receptors and phosphoinositide turnover. Annu Rev Pharmacol Toxicol. 29:1989;71-110.
    • (1989) Annu Rev Pharmacol Toxicol , vol.29 , pp. 71-110
    • Chuang, D.M.1
  • 38
    • 0015622215 scopus 로고
    • The 24 hour serum lithium level as a pronosticator of dosage requirements
    • Cooper T.B., Bergner P.E., Simpson G.M. The 24 hour serum lithium level as a pronosticator of dosage requirements. Am J Psychiatry. 130:1973;601-603.
    • (1973) Am J Psychiatry , vol.130 , pp. 601-603
    • Cooper, T.B.1    Bergner, P.E.2    Simpson, G.M.3
  • 39
    • 0025869265 scopus 로고
    • Long-lasting change in the membrane-associated protein kinase C activity in the hippocampal kindled rat
    • Daigen A., Aakiyama K., Otsuki S. Long-lasting change in the membrane-associated protein kinase C activity in the hippocampal kindled rat. Brain Res. 545:1991;131-136.
    • (1991) Brain Res , vol.545 , pp. 131-136
    • Daigen, A.1    Aakiyama, K.2    Otsuki, S.3
  • 40
    • 0002999524 scopus 로고
    • A two-dimensional threshold model of seasonal bipolar affective disorder
    • In: Magnusson D, Ohman A, editors Orlando, FL: Academic Press
    • Depue RA, Karuss SP, Spoont MR (1987): A two-dimensional threshold model of seasonal bipolar affective disorder. In: Magnusson D, Ohman A, editors. Psychopathology: An Interactional Perspective.Orlando, FL: Academic Press, 95-123.
    • (1987) Psychopathology: An Interactional Perspective , pp. 95-123
    • Depue, R.A.1    Karuss, S.P.2    Spoont, M.R.3
  • 41
    • 0022466347 scopus 로고
    • Lithium-induced reduction in intracellular inositol supply in cholinergically stimulated parotid gland
    • Downes C.P., Stone M.A. Lithium-induced reduction in intracellular inositol supply in cholinergically stimulated parotid gland. Biochem J. 234:1986;199-204.
    • (1986) Biochem J , vol.234 , pp. 199-204
    • Downes, C.P.1    Stone, M.A.2
  • 42
    • 0021722729 scopus 로고
    • The interaction of lithium with thyrotropin releasing hormone-stimulated lipid metabolism in GH3 pituitary tumor cells
    • Drummond A.H., Raeburn C.A. The interaction of lithium with thyrotropin releasing hormone-stimulated lipid metabolism in GH3 pituitary tumor cells. Biochem J. 224:1984;129-136.
    • (1984) Biochem J , vol.224 , pp. 129-136
    • Drummond, A.H.1    Raeburn, C.A.2
  • 44
    • 0032924793 scopus 로고    scopus 로고
    • Administration of dexmethasone up-regulates protein kinase C activity and the expression of and protein kinase C isozymes in the rat brain
    • Dwivedi Y., Pandey G.N. Administration of dexmethasone up-regulates protein kinase C activity and the expression of and protein kinase C isozymes in the rat brain. J Neurochem. 72:1999;380-387.
    • (1999) J Neurochem , vol.72 , pp. 380-387
    • Dwivedi, Y.1    Pandey, G.N.2
  • 45
    • 0025815750 scopus 로고
    • Molecular cloning and characterization of the acidic 80-kDa protein kinase C substrate from rat brain
    • Erusalimsky J.D., Brooks S.F., Herget T., et al. Molecular cloning and characterization of the acidic 80-kDa protein kinase C substrate from rat brain. J Biol Chem. 266:1991;7073-7080.
    • (1991) J Biol Chem , vol.266 , pp. 7073-7080
    • Erusalimsky, J.D.1    Brooks, S.F.2    Herget, T.3
  • 46
    • 0025162155 scopus 로고
    • Signaling through phosphatidylcholine breakdown
    • Exton J.H. Signaling through phosphatidylcholine breakdown. J Biol Chem. 265:1990;1-4.
    • (1990) J Biol Chem , vol.265 , pp. 1-4
    • Exton, J.H.1
  • 47
    • 0027156096 scopus 로고
    • Outcome after rapid vs. gradual discontinuation of lithium treatment in bipolar mood disorders
    • Faedda G.L., Tondo L., Baldessarini R.J., et al. Outcome after rapid vs. gradual discontinuation of lithium treatment in bipolar mood disorders. Arch Gen Psychiatry. 50:1993;448-455.
    • (1993) Arch Gen Psychiatry , vol.50 , pp. 448-455
    • Faedda, G.L.1    Tondo, L.2    Baldessarini, R.J.3
  • 48
    • 0026502059 scopus 로고
    • Inositol lipids and signal transduction in the nervous system: An update
    • Fisher S.K., Heacock A.M., Agranoff B.W. Inositol lipids and signal transduction in the nervous system An update . J Neurochem. 58:1992;18-38.
    • (1992) J Neurochem , vol.58 , pp. 18-38
    • Fisher, S.K.1    Heacock, A.M.2    Agranoff, B.W.3
  • 49
    • 0027278902 scopus 로고
    • Altered platelet protein kinase C activity in bipolar affective disorder, manic episode
    • Freidman E., Hoau Y.W., Levinson D., Connell T.A., Singh H. Altered platelet protein kinase C activity in bipolar affective disorder, manic episode. Biol Psychiatry. 33:1993;520-525.
    • (1993) Biol Psychiatry , vol.33 , pp. 520-525
    • Freidman, E.1    Hoau, Y.W.2    Levinson, D.3    Connell, T.A.4    Singh, H.5
  • 50
    • 0030071272 scopus 로고    scopus 로고
    • The relationship between antimanic agent for treatment of classic or dysphoric mania and length of hospital stay
    • Frye M.A., Altshuler L.L., Szuba M.P., et al. The relationship between antimanic agent for treatment of classic or dysphoric mania and length of hospital stay. J Clin Psychiatry. 57:1996;17-21.
    • (1996) J Clin Psychiatry , vol.57 , pp. 17-21
    • Frye, M.A.1    Altshuler, L.L.2    Szuba, M.P.3
  • 52
    • 0026715630 scopus 로고
    • Protein kinase C and dopamine transport - 1. Effects of amphetamine in vivo
    • Giambalvo C.T. Protein kinase C and dopamine transport - 1. Effects of amphetamine in vivo. Neuropharmacology. 31:1992;1201-1210.
    • (1992) Neuropharmacology , vol.31 , pp. 1201-1210
    • Giambalvo, C.T.1
  • 53
    • 0026621687 scopus 로고
    • Protein kinase C and dopamine transport - 2. Effects of amphetamine in vitro
    • Giambalvo C.T. Protein kinase C and dopamine transport - 2. Effects of amphetamine in vitro. Neuropharmacology. 31:1992;1211-1222.
    • (1992) Neuropharmacology , vol.31 , pp. 1211-1222
    • Giambalvo, C.T.1
  • 54
    • 0024349702 scopus 로고
    • Differences in the metabolism of inositol and phosphoinositides by cultured cells of neuronal and glial origin
    • Glanville N.T., Byres D.M., Cook H.W., Spence M.W., Palmer F.B. Differences in the metabolism of inositol and phosphoinositides by cultured cells of neuronal and glial origin. Biochem Biophys Acta. 1004:1989;169-179.
    • (1989) Biochem Biophys Acta , vol.1004 , pp. 169-179
    • Glanville, N.T.1    Byres, D.M.2    Cook, H.W.3    Spence, M.W.4    Palmer, F.B.5
  • 55
    • 0027385573 scopus 로고
    • Phosphorylation of neuromodulin in rat striatum after acute and repeated, intermittent amphetamine
    • Gnegy M.E., Hong P., Ferrell S.T. Phosphorylation of neuromodulin in rat striatum after acute and repeated, intermittent amphetamine. Brain Res Mol Brain Res. 20:1993;289-298.
    • (1993) Brain Res Mol Brain Res , vol.20 , pp. 289-298
    • Gnegy, M.E.1    Hong, P.2    Ferrell, S.T.3
  • 56
    • 0024507366 scopus 로고
    • Potentiation by lithium of CMP-phosphatidate formation in carbachol-stimulated rat cerebral-cortical slices and its reversal by myo-inositol
    • Godfrey P.P., McClue S.J., White A.M., Wood A.J., Grahame-Smith D.G. Potentiation by lithium of CMP-phosphatidate formation in carbachol-stimulated rat cerebral-cortical slices and its reversal by myo-inositol. Biochem J. 258:1989;621-624.
    • (1989) Biochem J , vol.258 , pp. 621-624
    • Godfrey, P.P.1    McClue, S.J.2    White, A.M.3    Wood, A.J.4    Grahame-Smith, D.G.5
  • 57
    • 0028900634 scopus 로고
    • Immunocytochemical localization of eight protein kinase C isozymes overexpressed in NIH 3T3 fibroblasts
    • Goodnight J., Mischak H., Kolch W., Mushinski J.F. Immunocytochemical localization of eight protein kinase C isozymes overexpressed in NIH 3T3 fibroblasts. J Biol Chem. 270:1995;9991-10001.
    • (1995) J Biol Chem , vol.270 , pp. 9991-10001
    • Goodnight, J.1    Mischak, H.2    Kolch, W.3    Mushinski, J.F.4
  • 61
    • 0026733192 scopus 로고
    • Chronic administration of lithium or other antidepressants increases levels of DARPP-32 in rat frontal cortex
    • Guitart X., Nestler E.J. Chronic administration of lithium or other antidepressants increases levels of DARPP-32 in rat frontal cortex. J Neurochem. 59:1992;1164-1167.
    • (1992) J Neurochem , vol.59 , pp. 1164-1167
    • Guitart, X.1    Nestler, E.J.2
  • 62
    • 0019127799 scopus 로고
    • The effects of lithium ion and other agents on the activity of myoinositol-1-phosphatase from bovine brain
    • Hallcher L.M., Sherman W.R. The effects of lithium ion and other agents on the activity of myoinositol-1-phosphatase from bovine brain. J Biol Chem. 255:1980;10896-10901.
    • (1980) J Biol Chem , vol.255 , pp. 10896-10901
    • Hallcher, L.M.1    Sherman, W.R.2
  • 63
    • 0025359658 scopus 로고
    • Rat-brain protein kinase-C-kinetic-analysis of substrate dependence, allosteric regulation and autophosphorylation
    • Hannun Y.A., Bell R.M. Rat-brain protein kinase-C-kinetic-analysis of substrate dependence, allosteric regulation and autophosphorylation. J Biol Chem. 265:1990;2962-2972.
    • (1990) J Biol Chem , vol.265 , pp. 2962-2972
    • Hannun, Y.A.1    Bell, R.M.2
  • 64
    • 0021995234 scopus 로고
    • Diagnostic categorization of psychiatric disturbance in Cushing's syndrome
    • Haskett R.F. Diagnostic categorization of psychiatric disturbance in Cushing's syndrome. Am J Psychiatry. 142:1985;911-916.
    • (1985) Am J Psychiatry , vol.142 , pp. 911-916
    • Haskett, R.F.1
  • 65
    • 0031149476 scopus 로고    scopus 로고
    • Activation of the Wnt signaling pathway: A molecular mechanism for lithium action
    • Hedgepeth C.M., Conrad L.J., Zhang J., Huang H.C., Lee V.M., Klein P.S. Activation of the Wnt signaling pathway A molecular mechanism for lithium action . Dev Biol. 185:1997;82-91.
    • (1997) Dev Biol , vol.185 , pp. 82-91
    • Hedgepeth, C.M.1    Conrad, L.J.2    Zhang, J.3    Huang, H.C.4    Lee, V.M.5    Klein, P.S.6
  • 67
    • 0030019604 scopus 로고    scopus 로고
    • Tamoxifen antagonizes proliferation and invasion of estrogen receptor-negative metastatic follicular thyroid cancer cells via protein kinase C
    • Hoelting T., Duh Q.Y., Clark O.H., Herfarth C. Tamoxifen antagonizes proliferation and invasion of estrogen receptor-negative metastatic follicular thyroid cancer cells via protein kinase C. Cancer Lett. 100:1996;89-93.
    • (1996) Cancer Lett , vol.100 , pp. 89-93
    • Hoelting, T.1    Duh, Q.Y.2    Clark, O.H.3    Herfarth, C.4
  • 68
    • 0022892593 scopus 로고
    • Inhibition of protein kinase C mediated signal transduction by tamoxifen. Importance for antitumour activity
    • Horgan K., Cooke E., Hallett M.B., Mansel R.E. Inhibition of protein kinase C mediated signal transduction by tamoxifen. Importance for antitumour activity. Biochem Pharmacol. 35:1986;4463-4465.
    • (1986) Biochem Pharmacol , vol.35 , pp. 4463-4465
    • Horgan, K.1    Cooke, E.2    Hallett, M.B.3    Mansel, R.E.4
  • 72
    • 0024457676 scopus 로고
    • The mechanism of protein kinase C activation
    • Huang K.P. The mechanism of protein kinase C activation. Trends Neurosci. 12:1989;425-432.
    • (1989) Trends Neurosci , vol.12 , pp. 425-432
    • Huang, K.P.1
  • 73
    • 0029042370 scopus 로고
    • Induction of immediate-early genes and the control of neurotransmitter-regulated gene expression within the nervous system
    • Hughes P., Dragunow M. Induction of immediate-early genes and the control of neurotransmitter-regulated gene expression within the nervous system. Pharmacol Rev. 47:1995;133-178.
    • (1995) Pharmacol Rev , vol.47 , pp. 133-178
    • Hughes, P.1    Dragunow, M.2
  • 74
    • 0030032338 scopus 로고    scopus 로고
    • Initiation and adaptation: A paradigm for understanding psychotropic drug action
    • Hyman S.E., Nestler E.J. Initiation and adaptation A paradigm for understanding psychotropic drug action . Am J Psychiatry. 153:1996;151-162.
    • (1996) Am J Psychiatry , vol.153 , pp. 151-162
    • Hyman, S.E.1    Nestler, E.J.2
  • 75
    • 0032473355 scopus 로고    scopus 로고
    • Axin, a negative regulator of the Wnt signaling pathway forms a complex with GSK-3β and β-catenin
    • Ikeda S., Kishida S., Yamamoto H., Murai H., Koyama S., Kikuchi A. Axin, a negative regulator of the Wnt signaling pathway forms a complex with GSK-3β and β-catenin. Embo J. 17:1997;1371-1384.
    • (1997) Embo J , vol.17 , pp. 1371-1384
    • Ikeda, S.1    Kishida, S.2    Yamamoto, H.3    Murai, H.4    Koyama, S.5    Kikuchi, A.6
  • 76
    • 0032870743 scopus 로고    scopus 로고
    • Molecular mechanisms underlying mood-stabilization in manic-depressive illness: The phenotype challenge
    • (in press)
    • Ikonomov O, Manji HK (in press): Molecular mechanisms underlying mood-stabilization in manic-depressive illness: The phenotype challenge. Am J Psychiatry.
    • Am J Psychiatry
    • Ikonomov, O.1    Manji, H.K.2
  • 77
    • 0025078379 scopus 로고
    • Selective post-transcription down-regulation of protein kinase C isoenzymes in Leukemic T cells chronically treated with phorbol ester
    • Isakov N., McMahon P., Altman A. Selective post-transcription down-regulation of protein kinase C isoenzymes in Leukemic T cells chronically treated with phorbol ester. J Biol Chem. 265:1990;2091-2097.
    • (1990) J Biol Chem , vol.265 , pp. 2091-2097
    • Isakov, N.1    McMahon, P.2    Altman, A.3
  • 78
    • 0031443572 scopus 로고    scopus 로고
    • Enhanced dopamine release and phosphorylation of synapsin I and neuromodulin in striatal synaptosomes after repeated amphetamine
    • Iwata S.I., Hewlett G.H., Ferrell S.T., Kantor L., Gnegy M.E. Enhanced dopamine release and phosphorylation of synapsin I and neuromodulin in striatal synaptosomes after repeated amphetamine. J Pharmacol Exp Ther. 283:1997;1445-1452.
    • (1997) J Pharmacol Exp Ther , vol.283 , pp. 1445-1452
    • Iwata, S.I.1    Hewlett, G.H.2    Ferrell, S.T.3    Kantor, L.4    Gnegy, M.E.5
  • 79
    • 0030910710 scopus 로고    scopus 로고
    • Amphetamine increases the phosphorylation of neuromodulin and synapsin I in rat striatal synaptomosomes
    • Iwata S., Hewlett G.H., Gnegy M.E. Amphetamine increases the phosphorylation of neuromodulin and synapsin I in rat striatal synaptomosomes. Synapse. 26:1997;281-291.
    • (1997) Synapse , vol.26 , pp. 281-291
    • Iwata, S.1    Hewlett, G.H.2    Gnegy, M.E.3
  • 80
    • 0026559568 scopus 로고
    • Regulating transcription factor activity by phosphorylation
    • Jackson S. Regulating transcription factor activity by phosphorylation. Trends Cell Biol. 2:1992;104-108.
    • (1992) Trends Cell Biol , vol.2 , pp. 104-108
    • Jackson, S.1
  • 81
    • 0023004544 scopus 로고
    • Suicide and bipolar disorders
    • Jamison K.R. Suicide and bipolar disorders. Ann N Y Acad Sci. 487:1986;301-315.
    • (1986) Ann N Y Acad Sci , vol.487 , pp. 301-315
    • Jamison, K.R.1
  • 82
    • 0015520940 scopus 로고
    • A cholinergic-adrenergic hypothesis of mania and depression
    • Janowsky D.S., El-Yousef M.K., Davis J.M., Sekerke H.J. A cholinergic-adrenergic hypothesis of mania and depression. Lancet. 2:1972;632-635.
    • (1972) Lancet , vol.2 , pp. 632-635
    • Janowsky, D.S.1    El-Yousef, M.K.2    Davis, J.M.3    Sekerke, H.J.4
  • 83
    • 0030975168 scopus 로고    scopus 로고
    • Altered protein phosphorylation in the rat brain following chronic lithium and carbamazepine treatments
    • Jensen J.B., Mork A. Altered protein phosphorylation in the rat brain following chronic lithium and carbamazepine treatments. Eur Neuropsychopharmacol. 7:1997;173-179.
    • (1997) Eur Neuropsychopharmacol , vol.7 , pp. 173-179
    • Jensen, J.B.1    Mork, A.2
  • 84
    • 0032947795 scopus 로고    scopus 로고
    • Anti-bipolar therapy: Mechanism of action of lithium
    • Jope R.S. Anti-bipolar therapy Mechanism of action of lithium . Mol Psychiatry. 4:1999;117-128.
    • (1999) Mol Psychiatry , vol.4 , pp. 117-128
    • Jope, R.S.1
  • 85
    • 0033013011 scopus 로고    scopus 로고
    • A bimodal model of the mechanism of action of lithium
    • Jope R.S. A bimodal model of the mechanism of action of lithium. Mol Psychiatry. 4:1999;21-25.
    • (1999) Mol Psychiatry , vol.4 , pp. 21-25
    • Jope, R.S.1
  • 86
    • 0028219225 scopus 로고
    • Lithium and brain signal transduction systems
    • Jope R.S., Williams M.B. Lithium and brain signal transduction systems. Biochem Pharmacol. 77:1994;429-441.
    • (1994) Biochem Pharmacol , vol.77 , pp. 429-441
    • Jope, R.S.1    Williams, M.B.2
  • 87
    • 0031968868 scopus 로고    scopus 로고
    • A new intellectual framework for psychiatry
    • Kandel E.R. A new intellectual framework for psychiatry. Am J Psychiatry. 155:1998;457-469.
    • (1998) Am J Psychiatry , vol.155 , pp. 457-469
    • Kandel, E.R.1
  • 88
    • 0031933722 scopus 로고    scopus 로고
    • Protein kinase C inhibitors block amphetamine-mediated dopamine release in rat striatal slices
    • Kantor L., Gnegy M.E. Protein kinase C inhibitors block amphetamine-mediated dopamine release in rat striatal slices. J Pharmacol Exp Ther. 284:1998;592-598.
    • (1998) J Pharmacol Exp Ther , vol.284 , pp. 592-598
    • Kantor, L.1    Gnegy, M.E.2
  • 89
    • 0026661584 scopus 로고
    • Control of transcription factors by signal transduction pathways: The beginning of the end
    • Karin M., Smeal T. Control of transcription factors by signal transduction pathways The beginning of the end . Trends Biochem Sci. 17:1992;418-422.
    • (1992) Trends Biochem Sci , vol.17 , pp. 418-422
    • Karin, M.1    Smeal, T.2
  • 91
    • 0024515583 scopus 로고
    • Limited proteolysis of protein kinase C subspecies by calcium-dependent neutral protease (calpain)
    • Kishimoto A., Mikawa K., Hashimoto K., et al. Limited proteolysis of protein kinase C subspecies by calcium-dependent neutral protease (calpain). J Biol Chem. 264:1989;4088-4092.
    • (1989) J Biol Chem , vol.264 , pp. 4088-4092
    • Kishimoto, A.1    Mikawa, K.2    Hashimoto, K.3
  • 92
    • 0029776032 scopus 로고    scopus 로고
    • A molecular mechanism for the effect of lithium on development
    • Klein P.S., Melton D.A. A molecular mechanism for the effect of lithium on development. Proc Natl Acad Sci USA. 93:1996;8455-8459.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 8455-8459
    • Klein, P.S.1    Melton, D.A.2
  • 93
    • 0024416759 scopus 로고
    • The addition of lithium to carbamazepine: Antidepressant efficacy in treatment-resistant mania
    • Kramlinger K.G., Post R.M. The addition of lithium to carbamazepine Antidepressant efficacy in treatment-resistant mania . Arch Gen Psychiatry. 46:1989;794-800.
    • (1989) Arch Gen Psychiatry , vol.46 , pp. 794-800
    • Kramlinger, K.G.1    Post, R.M.2
  • 94
    • 0024515583 scopus 로고
    • Limited proteolysis of protein kinase C subspecies by calcium-dependent neural protease (calpain)
    • Kuroda T., Nishizuka Y. Limited proteolysis of protein kinase C subspecies by calcium-dependent neural protease (calpain). J Biol Chem. 264:1989;4088-4092.
    • (1989) J Biol Chem , vol.264 , pp. 4088-4092
    • Kuroda, T.1    Nishizuka, Y.2
  • 95
    • 0025441935 scopus 로고
    • Neuronal properties and trophic activities of immortalized hippocampal cells from embryonic and young adult mice
    • Lee H.J., Hammond D.N., Large T.H., Roback J.D., Sim J.A., Brown D.A., Otten U.H., Wainer B.H. Neuronal properties and trophic activities of immortalized hippocampal cells from embryonic and young adult mice. J Neurosci. 10:1990;1779-1787.
    • (1990) J Neurosci , vol.10 , pp. 1779-1787
    • Lee, H.J.1    Hammond, D.N.2    Large, T.H.3    Roback, J.D.4    Sim, J.A.5    Brown, D.A.6    Otten, U.H.7    Wainer, B.H.8
  • 97
    • 0027448160 scopus 로고
    • Differential expression and subcellular localization of protein kinase C alpha, beta, gamma, delta, and epsilon isoforms in SH-SY5Y neuroblastoma cells: Modifications during differentiation
    • Leli U., Shea T.B., Cataldo A., et al. Differential expression and subcellular localization of protein kinase C alpha, beta, gamma, delta, and epsilon isoforms in SH-SY5Y neuroblastoma cells Modifications during differentiation . J Neurochem. 60:1993;289-298.
    • (1993) J Neurochem , vol.60 , pp. 289-298
    • Leli, U.1    Shea, T.B.2    Cataldo, A.3
  • 98
    • 0023461332 scopus 로고
    • Role of receptor coupling to phosphoinositide metabolism in the therapeutic action of lithium
    • Lenox R.H. Role of receptor coupling to phosphoinositide metabolism in the therapeutic action of lithium. Adv Exp Med Biol. 221:1987;515-530.
    • (1987) Adv Exp Med Biol , vol.221 , pp. 515-530
    • Lenox, R.H.1
  • 100
    • 0026567408 scopus 로고
    • Chronic lithium administration alters a prominent PKC substrate in rat hippocampus
    • Lenox R.H., Watson D.G.J.P., Ellis J. Chronic lithium administration alters a prominent PKC substrate in rat hippocampus. Brain Res. 570:1992;333-340.
    • (1992) Brain Res , vol.570 , pp. 333-340
    • Lenox, R.H.1    Watson, D.G.J.P.2    Ellis, J.3
  • 101
    • 0028219446 scopus 로고
    • Lithium and the brain: A psychopharmacological strategy to a molecular basis for manic depressive illness
    • Lenox R.H., Watson D.G. Lithium and the brain A psychopharmacological strategy to a molecular basis for manic depressive illness . Clin Chem. 40:1994;309-314.
    • (1994) Clin Chem , vol.40 , pp. 309-314
    • Lenox, R.H.1    Watson, D.G.2
  • 102
    • 0028850086 scopus 로고
    • Selective inhibition of the expression of signal transduction proteins by lithium in nerve growth factor-differentiated PC12 cells
    • Li X., Jope R.S. Selective inhibition of the expression of signal transduction proteins by lithium in nerve growth factor-differentiated PC12 cells. J Neurochem. 65:1995;2500-2508.
    • (1995) J Neurochem , vol.65 , pp. 2500-2508
    • Li, X.1    Jope, R.S.2
  • 104
    • 0026556947 scopus 로고
    • Phorbol ester-induced down-regulation of the 80-kDa myristoylated alanine-rich C-kinase substrate-related protein in Swiss 3T3 fibroblasts
    • Linder D., Gschwendt M., Marks F. Phorbol ester-induced down-regulation of the 80-kDa myristoylated alanine-rich C-kinase substrate-related protein in Swiss 3T3 fibroblasts. J Biol Chem. 267:1992;24-26.
    • (1992) J Biol Chem , vol.267 , pp. 24-26
    • Linder, D.1    Gschwendt, M.2    Marks, F.3
  • 105
    • 0037742375 scopus 로고    scopus 로고
    • Valproate: A reappraisal of its pharmacodynamic properties and mechanisms of action
    • Loscher W. Valproate A reappraisal of its pharmacodynamic properties and mechanisms of action . Prog Neurobiol. 58:1999;31-59.
    • (1999) Prog Neurobiol , vol.58 , pp. 31-59
    • Loscher, W.1
  • 106
    • 0031469645 scopus 로고    scopus 로고
    • WNT-7a induces axonal remodeling and increases Synapsin I levels in cerebellar neurons
    • Lucas F.R., Salinas P.C. WNT-7a induces axonal remodeling and increases Synapsin I levels in cerebellar neurons. Dev Biol. 192:1997;31-44.
    • (1997) Dev Biol , vol.192 , pp. 31-44
    • Lucas, F.R.1    Salinas, P.C.2
  • 107
    • 0003101634 scopus 로고
    • Animal models for the symptoms of mania
    • In: Bolton A, Baker G, Martin-Iverson M, editors Totowa, NJ: Humana Press Inc.
    • Lyon M (1991): Animal models for the symptoms of mania. In: Bolton A, Baker G, Martin-Iverson M, editors. Neuromethods, Vol. 18: Animal Models in Psychiatry I. Totowa, NJ: Humana Press Inc.
    • (1991) Neuromethods, Vol. 18: Animal Models in Psychiatry , vol.1
    • Lyon, M.1
  • 108
    • 0029057901 scopus 로고
    • Antiepileptic drug mechanisms of action
    • MacDonald R.L., Kelly K.M. Antiepileptic drug mechanisms of action. Epilepsia. 36:(suppl 2):1995;S2-S12.
    • (1995) Epilepsia , vol.36 , Issue.SUPPL. 2
    • MacDonald, R.L.1    Kelly, K.M.2
  • 109
    • 0002066894 scopus 로고
    • The stability of constrained randomness: Lithium prophylaxis at several neurobiological levels
    • R.M. Post, & J.C. Ballenger. Baltimore: Williams & Wilkins
    • Mandell A.J., Knapp S., Ehlers C., et al. The stability of constrained randomness Lithium prophylaxis at several neurobiological levels . Post R.M., Ballenger J.C. Neurobiology of Mood Disorders. 1984;744-776 Williams & Wilkins, Baltimore.
    • (1984) Neurobiology of Mood Disorders , pp. 744-776
    • Mandell, A.J.1    Knapp, S.2    Ehlers, C.3
  • 110
    • 0026623287 scopus 로고
    • G proteins: Implications for psychiatry
    • Manji HK (1992): G proteins: implications for psychiatry. Am J Psychiatry 149:746-460.
    • (1992) Am J Psychiatry , vol.149 , pp. 746-460
    • Manji, H.K.1
  • 111
    • 0027366278 scopus 로고
    • Lithium decreases membrane-associated Protein kinase C in hippocampus: Selectivity for the a isozyme
    • Manji H.K., Etcheberrigaray R., Chen G., Olds J.L. Lithium decreases membrane-associated Protein kinase C in hippocampus Selectivity for the a isozyme . J Neurochem. 61:1993;2303-2310.
    • (1993) J Neurochem , vol.61 , pp. 2303-2310
    • Manji, H.K.1    Etcheberrigaray, R.2    Chen, G.3    Olds, J.L.4
  • 112
    • 0030455770 scopus 로고    scopus 로고
    • Regulation of signal transduction pathways by mood-stabilizing agents: Implications for the delayed onset of therapeutic efficacy
    • Manji H.K., Chen G., Hsiao J.K., et al. Regulation of signal transduction pathways by mood-stabilizing agents implications for the delayed onset of therapeutic efficacy . J Clin Psychiatry. 57:(suppl 13):1996;34-46.
    • (1996) J Clin Psychiatry , vol.57 , Issue.SUPPL. 13 , pp. 34-46
    • Manji, H.K.1    Chen, G.2    Hsiao, J.K.3
  • 113
    • 0027972567 scopus 로고
    • Long-term action of lithium: A role for transcriptional and posttranscriptional factors regulated by protein kinase C
    • Manji H.K., Lenox R.H. Long-term action of lithium A role for transcriptional and posttranscriptional factors regulated by protein kinase C . Synapse. 16:1994;11-28.
    • (1994) Synapse , vol.16 , pp. 11-28
    • Manji, H.K.1    Lenox, R.H.2
  • 114
    • 0031815122 scopus 로고    scopus 로고
    • Lithium: A unique cation in biology and medicine
    • Manji H.K., Lenox R.H. Lithium A unique cation in biology and medicine . Neuropsychopharmacology. 19:1998;161-240.
    • (1998) Neuropsychopharmacology , vol.19 , pp. 161-240
    • Manji, H.K.1    Lenox, R.H.2
  • 115
    • 0032827466 scopus 로고    scopus 로고
    • Lithium at 50: Have the neuroprotective properties of this unique cation been overlooked?
    • (in press)
    • Manji HK, Moore GJ, Chen G (in press): Lithium at 50: Have the neuroprotective properties of this unique cation been overlooked? Biol Psychiatry.
    • Biol Psychiatry
    • Manji, H.K.1    Moore, G.J.2    Chen, G.3
  • 116
    • 0029044932 scopus 로고
    • Signal transduction pathways. Molecular targets for lithium's actions
    • Manji H.K., Potter W.Z., Lenox R.H. Signal transduction pathways. Molecular targets for lithium's actions. Arch Gen Psychiatry. 52:1995;531-543.
    • (1995) Arch Gen Psychiatry , vol.52 , pp. 531-543
    • Manji, H.K.1    Potter, W.Z.2    Lenox, R.H.3
  • 117
    • 0023091203 scopus 로고
    • Down regulation of Protein kinase C in neuronal cells: Effects on neurotransmitter release
    • Matthies H.J.G., Palfrey H.C., Hirning L.D., Miller R.J. Down regulation of Protein kinase C in neuronal cells Effects on neurotransmitter release . J Neuroscience. 7:1987;1198-1206.
    • (1987) J Neuroscience , vol.7 , pp. 1198-1206
    • Matthies, H.J.G.1    Palfrey, H.C.2    Hirning, L.D.3    Miller, R.J.4
  • 118
    • 0029949167 scopus 로고    scopus 로고
    • A randomized comparison of divalproex oral loading versus haloperidol in the initial treatment of acute psychotic mania
    • McElroy S.L., Keck P.E., Stanton S.P., et al. A randomized comparison of divalproex oral loading versus haloperidol in the initial treatment of acute psychotic mania. J Clin Psychiatry. 57:1996;142-146.
    • (1996) J Clin Psychiatry , vol.57 , pp. 142-146
    • McElroy, S.L.1    Keck, P.E.2    Stanton, S.P.3
  • 119
    • 0025828318 scopus 로고
    • Phosphorylation-dependent binding of a synthetic MARCKS peptide to calmodulin
    • McIlroy B.K., Walters J.D., Blackshear P.J., Johnson J.D. Phosphorylation-dependent binding of a synthetic MARCKS peptide to calmodulin. J Biol Chem. 266:1991;4959-4966.
    • (1991) J Biol Chem , vol.266 , pp. 4959-4966
    • McIlroy, B.K.1    Walters, J.D.2    Blackshear, P.J.3    Johnson, J.D.4
  • 120
    • 0032564337 scopus 로고    scopus 로고
    • Effect of reduced myristoylated alanine-rich C kinase substrate expression on hippocampal mossy fiber development and spatial learning in mutant mice: Transgenic rescue and interactions with gene background
    • McNamara R.K., Stumpo D.J., Morel L.M., Lewis M.H., Wakeland E.K., Blackshear P.J., Lenox R.H. Effect of reduced myristoylated alanine-rich C kinase substrate expression on hippocampal mossy fiber development and spatial learning in mutant mice Transgenic rescue and interactions with gene background . Proc Natl Acad Sci USA. 95:1998;14517-14522.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 14517-14522
    • McNamara, R.K.1    Stumpo, D.J.2    Morel, L.M.3    Lewis, M.H.4    Wakeland, E.K.5    Blackshear, P.J.6    Lenox, R.H.7
  • 121
    • 0026602565 scopus 로고
    • The importance of serotonin-dopamine interactions in the action of clozapine
    • Meltzer HY (1992): The importance of serotonin-dopamine interactions in the action of clozapine. Br J Psychiatry 17(suppl):22-29.
    • (1992) Br J Psychiatry , vol.17 , Issue.SUPPL. , pp. 22-29
    • Meltzer, H.Y.1
  • 123
    • 0025959674 scopus 로고
    • Stimulus-transcription coupling in the nervous system: Involvement of the inducible proto-oncogenes Fos and Jun
    • Morgan J.I., Curran T. Stimulus-transcription coupling in the nervous system Involvement of the inducible proto-oncogenes Fos and Jun . Annu Rev Neurosci. 14:1991;421-451.
    • (1991) Annu Rev Neurosci , vol.14 , pp. 421-451
    • Morgan, J.I.1    Curran, T.2
  • 124
    • 0027007777 scopus 로고
    • Effects of lithium on second messenger systems in the brain
    • Mork A., Geisler A., Hollund P. Effects of lithium on second messenger systems in the brain. Pharmacol Toxicol. 71:(suppl 1):1992;4-17.
    • (1992) Pharmacol Toxicol , vol.71 , Issue.SUPPL. 1 , pp. 4-17
    • Mork, A.1    Geisler, A.2    Hollund, P.3
  • 126
    • 0025912111 scopus 로고
    • Lithium and the phosphoinositide cycle: An example of uncompetitive inhibition and its pharmacological consequences
    • Nahorski S.R., Ragan C.I., Challiss R.A.J. Lithium and the phosphoinositide cycle An example of uncompetitive inhibition and its pharmacological consequences . Trends Pharmacol Sci. 12:1991;297-303.
    • (1991) Trends Pharmacol Sci , vol.12 , pp. 297-303
    • Nahorski, S.R.1    Ragan, C.I.2    Challiss, R.A.J.3
  • 127
  • 128
    • 0027817597 scopus 로고
    • The effect of psychotropic drugs on the interaction of protein kinase C with second messenger systems in the rat cerebral cortex
    • Nalepa I. The effect of psychotropic drugs on the interaction of protein kinase C with second messenger systems in the rat cerebral cortex. Pol J Pharmacol. 45:(5-6):1993;521-532.
    • (1993) Pol J Pharmacol , vol.45 , Issue.56 , pp. 521-532
    • Nalepa, I.1
  • 129
    • 0028230897 scopus 로고
    • The effect of psychotropic drugs on the interaction of protein kinase C with second messenger systems in the rat cerebral cortex
    • Nalepa I. The effect of psychotropic drugs on the interaction of protein kinase C with second messenger systems in the rat cerebral cortex. Pol J Pharmacol. 46:(1-2):1994;1-14.
    • (1994) Pol J Pharmacol , vol.46 , Issue.12 , pp. 1-14
    • Nalepa, I.1
  • 131
    • 0028811653 scopus 로고
    • Protein kinase C: Structure, function and regulation
    • Newton AC (1995): Protein kinase C: Structure, function and regulation. J Biol Chem 270:28495-24898.
    • (1995) J Biol Chem , vol.270 , pp. 28495-24898
    • Newton, A.C.1
  • 132
    • 0026451081 scopus 로고
    • Intracellular signaling by hydrolysis of phospholipids and activation of protein kinase C
    • Nishizuka Y. Intracellular signaling by hydrolysis of phospholipids and activation of protein kinase C. Science. 258:1992;607-614.
    • (1992) Science , vol.258 , pp. 607-614
    • Nishizuka, Y.1
  • 133
    • 0023764676 scopus 로고
    • Specific and direct binding of protein kinase C to an immobilized tamoxifen analogue
    • O'Brian C.A., Housey G.M., Weinstein I.B. Specific and direct binding of protein kinase C to an immobilized tamoxifen analogue. Cancer Res. 48:1988;3626-3629.
    • (1988) Cancer Res , vol.48 , pp. 3626-3629
    • O'Brian, C.A.1    Housey, G.M.2    Weinstein, I.B.3
  • 134
    • 0025963046 scopus 로고
    • Synaptosomal protein kinase C subspecies: B. Down-regulation promoted by phorbol ester and its effect on evoked norepinephrine release
    • Oda T., Sherman M.S., Nishizuka Y. Synaptosomal protein kinase C subspecies B. Down-regulation promoted by phorbol ester and its effect on evoked norepinephrine release . J Neurochem. 56:1991;1263-1269.
    • (1991) J Neurochem , vol.56 , pp. 1263-1269
    • Oda, T.1    Sherman, M.S.2    Nishizuka, Y.3
  • 135
    • 0024423978 scopus 로고
    • Imaging of memory-specific changes in the distribution of protein kinase C in the hippocampus
    • Olds J.L., Anderson M.L., McPhie D.L., Olton D., Mishkin M., Alkon D.L. Imaging of memory-specific changes in the distribution of protein kinase C in the hippocampus. Science. 245:1989;866-869.
    • (1989) Science , vol.245 , pp. 866-869
    • Olds, J.L.1    Anderson, M.L.2    McPhie, D.L.3    Olton, D.4    Mishkin, M.5    Alkon, D.L.6
  • 136
    • 0025514412 scopus 로고
    • Discrimination learning alters the distribution of protein kinase C in the hippocampus of rats
    • Olds J.L., Golski S., McPhie D.L., Staten L.D., Alkon D.L. Discrimination learning alters the distribution of protein kinase C in the hippocampus of rats. J Neurosci. 10:1990;3707-3713.
    • (1990) J Neurosci , vol.10 , pp. 3707-3713
    • Olds, J.L.1    Golski, S.2    McPhie, D.L.3    Staten, L.D.4    Alkon, D.L.5
  • 137
    • 0025423954 scopus 로고
    • Localization of the MARCKS (87 kDa) protein, a major specific substrate for the protein kinase C, in rat Brian
    • Ouimet C.C., Wang J.K.T., Walaas S.I., et al. Localization of the MARCKS (87 kDa) protein, a major specific substrate for the protein kinase C, in rat Brian. J Neurosci. 10:1990;1683-1698.
    • (1990) J Neurosci , vol.10 , pp. 1683-1698
    • Ouimet, C.C.1    Wang, J.K.T.2    Walaas, S.I.3
  • 138
    • 0030723121 scopus 로고    scopus 로고
    • Lithium increases transcription factor binding to AP-1 and cyclic AMP-responsive element in cultured neurons and rat brain
    • Ozaki N., Chuang D.M. Lithium increases transcription factor binding to AP-1 and cyclic AMP-responsive element in cultured neurons and rat brain. J Neurochemistry. 69:1997;2336-2344.
    • (1997) J Neurochemistry , vol.69 , pp. 2336-2344
    • Ozaki, N.1    Chuang, D.M.2
  • 141
    • 0029969483 scopus 로고    scopus 로고
    • Phorbol ester intracerebroventricularly induces a behavioral hypoactivity that is not affected by chronic or acute lithium
    • Patishi Y., Bersudsky Y., Belmaker R.H. Phorbol ester intracerebroventricularly induces a behavioral hypoactivity that is not affected by chronic or acute lithium. Eur Neuropsychopharmacol. 6:1996;39-41.
    • (1996) Eur Neuropsychopharmacol , vol.6 , pp. 39-41
    • Patishi, Y.1    Bersudsky, Y.2    Belmaker, R.H.3
  • 144
    • 0026611731 scopus 로고
    • Mechanisms of action of anti-convulsants in affective disorders: Comparisons with lithium
    • Post R.M., Weiss S.R., Chuang D.M. Mechanisms of action of anti-convulsants in affective disorders comparisons with lithium . J Clin Psychopharmacol. 12:1992;42S-52S.
    • (1992) J Clin Psychopharmacol , vol.12
    • Post, R.M.1    Weiss, S.R.2    Chuang, D.M.3
  • 146
    • 0025015267 scopus 로고
    • Role of Phosphoinositides in Transmembrane Signaling
    • Rana R.S., Hokin L.E. Role of Phosphoinositides in Transmembrane Signaling. Physiol Rev. 70:1990;115-164.
    • (1990) Physiol Rev , vol.70 , pp. 115-164
    • Rana, R.S.1    Hokin, L.E.2
  • 147
    • 0018867841 scopus 로고
    • Lithium: A brake in the rising cost of mental illness
    • Reifman A., Wyatt R.J. Lithium A brake in the rising cost of mental illness . Arch Gen Psychiatry. 37:1980;385-388.
    • (1980) Arch Gen Psychiatry , vol.37 , pp. 385-388
    • Reifman, A.1    Wyatt, R.J.2
  • 148
    • 0023185610 scopus 로고
    • Interactions between lithium, calcium, diacylglycerides and phorbol esters in the regulation of ACTH release from AtT-20 cells
    • Reisine T., Zatz M. Interactions between lithium, calcium, diacylglycerides and phorbol esters in the regulation of ACTH release from AtT-20 cells. J Neurochem. 49:1987;884-889.
    • (1987) J Neurochem , vol.49 , pp. 884-889
    • Reisine, T.1    Zatz, M.2
  • 149
    • 0025768357 scopus 로고
    • The mechanisms of action of lithium. II. Effects on adenylate cyclase activity and beta-adrenergic receptor binding in normal subjects
    • Risby E.D., Hsiao J.K., Manji H.K., et al. The mechanisms of action of lithium. II. Effects on adenylate cyclase activity and beta-adrenergic receptor binding in normal subjects. Arch Gen Psychiatry. 48:1991;513-524.
    • (1991) Arch Gen Psychiatry , vol.48 , pp. 513-524
    • Risby, E.D.1    Hsiao, J.K.2    Manji, H.K.3
  • 150
    • 0026291394 scopus 로고
    • The role of protein kinase C and its neuronal substrates dephosphin. B-50, and MARCKS in neurotransmitter release
    • Robinson P.J. The role of protein kinase C and its neuronal substrates dephosphin. B-50, and MARCKS in neurotransmitter release. Mol Neurobiol. 5:1991;87-130.
    • (1991) Mol Neurobiol , vol.5 , pp. 87-130
    • Robinson, P.J.1
  • 151
    • 0025050694 scopus 로고
    • Antiepileptic drugs: Pharmacological mechanisms and clinical efficacy with consideration of promising development stage compounds
    • Rogawski M.A., Porter R.J. Antiepileptic drugs Pharmacological mechanisms and clinical efficacy with consideration of promising development stage compounds . Pharmacol Rev. 42:1990;223-286.
    • (1990) Pharmacol Rev , vol.42 , pp. 223-286
    • Rogawski, M.A.1    Porter, R.J.2
  • 152
    • 0031928243 scopus 로고    scopus 로고
    • Prostate cancer cell growth inhibition by tamoxifen is associated with inhibition of protein kinase C and induction of p21(waf1/cip1)
    • Rohlff C., Blagosklonny M.V., Kyle E., Kesari A., Kim I.Y., Zelner D.J., Hakim F., Trepel J., Bergan R.C. Prostate cancer cell growth inhibition by tamoxifen is associated with inhibition of protein kinase C and induction of p21(waf1/cip1). Prostate. 37:1998;51-59.
    • (1998) Prostate , vol.37 , pp. 51-59
    • Rohlff, C.1    Blagosklonny, M.V.2    Kyle, E.3    Kesari, A.4    Kim, I.Y.5    Zelner, D.J.6    Hakim, F.7    Trepel, J.8    Bergan, R.C.9
  • 153
    • 0025096430 scopus 로고
    • Activation of protein kinase C results in the displacement of its myristoylated, alanine-rich substrate from punctuate structures in macrophage filopodia
    • Rosen A., Keenan K.F., Thelen M., Nairn A.C., Aderem A. Activation of protein kinase C results in the displacement of its myristoylated, alanine-rich substrate from punctuate structures in macrophage filopodia. J Exp Med. 172:1990;1211-1215.
    • (1990) J Exp Med , vol.172 , pp. 1211-1215
    • Rosen, A.1    Keenan, K.F.2    Thelen, M.3    Nairn, A.C.4    Aderem, A.5
  • 154
    • 0024709982 scopus 로고
    • Signal sorting and amplification through G protein-coupled receptors
    • Ross E.M. Signal sorting and amplification through G protein-coupled receptors. Neuron. 3:1989;141-152.
    • (1989) Neuron , vol.3 , pp. 141-152
    • Ross, E.M.1
  • 155
    • 0345085987 scopus 로고
    • Lithium research at the Psychopharmacology Research Unit, Risskov, Denmark: A historical account
    • M. Schou, & E. Stromgren. London: Academic Press
    • Schou M. Lithium research at the Psychopharmacology Research Unit, Risskov, Denmark A historical account . Schou M., Stromgren E. Origin, Prevention and Treatment of Affective Disorders. 1979;1-8 Academic Press, London.
    • (1979) Origin, Prevention and Treatment of Affective Disorders , pp. 1-8
    • Schou, M.1
  • 156
    • 0002276676 scopus 로고
    • Clinical aspects of lithium in psychiatry
    • N.J. Birch. London: Academic Press
    • Schou M. Clinical aspects of lithium in psychiatry. Birch N.J. Lithium and the Cell. 1991;1-6 Academic Press, London.
    • (1991) Lithium and the Cell , pp. 1-6
    • Schou, M.1
  • 157
    • 0026099148 scopus 로고
    • Cloning and molecular characterization of the murine macrophage "68-kDa" protein kinase C substrate and its regulation by bacterial lipopolysaccharide
    • Seykora J.T., Ravetch J.V., Aderem A. Cloning and molecular characterization of the murine macrophage "68-kDa" protein kinase C substrate and its regulation by bacterial lipopolysaccharide. Proc Natl Acad Sci USA. 88:1991;2505-2509.
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 2505-2509
    • Seykora, J.T.1    Ravetch, J.V.2    Aderem, A.3
  • 158
    • 0025267015 scopus 로고
    • The regulation and function c-fos and other immediate early genes in the nervous system
    • Sheng M., Greenberg M.E. The regulation and function c-fos and other immediate early genes in the nervous system. Neuron. 4:1990;477-485.
    • (1990) Neuron , vol.4 , pp. 477-485
    • Sheng, M.1    Greenberg, M.E.2
  • 160
    • 0026543403 scopus 로고
    • Lithium treatment of affective disorders, effects of lithium on the inositol phospholipid and cyclic AMP signaling pathways
    • Sillence D., Downes C.P. Lithium treatment of affective disorders, effects of lithium on the inositol phospholipid and cyclic AMP signaling pathways. Biochem Biophys Acta. 1138:1992;46-52.
    • (1992) Biochem Biophys Acta , vol.1138 , pp. 46-52
    • Sillence, D.1    Downes, C.P.2
  • 161
    • 0026009999 scopus 로고
    • Carbamazepine compared with lithium in the treatment of mania
    • Small J.G., Klapper M.H., Milstein V., et al. Carbamazepine compared with lithium in the treatment of mania. Arch Gen Psychiatry. 48:1991;915-921.
    • (1991) Arch Gen Psychiatry , vol.48 , pp. 915-921
    • Small, J.G.1    Klapper, M.H.2    Milstein, V.3
  • 162
    • 0026763345 scopus 로고
    • Chronic lithium treatment impairs phosphatidylinositol hydrolysis in membranes from rat brain regions
    • Song L., Jope R. Chronic lithium treatment impairs phosphatidylinositol hydrolysis in membranes from rat brain regions. J Neurochem. 58:1992;2200-2206.
    • (1992) J Neurochem , vol.58 , pp. 2200-2206
    • Song, L.1    Jope, R.2
  • 164
    • 0030449964 scopus 로고    scopus 로고
    • Lithium inhibits glycogen synthase kinase-3 activity and mimics wingless signalling in intact cells
    • Stambolic V., Laurent R., Woodgett J.R. Lithium inhibits glycogen synthase kinase-3 activity and mimics wingless signalling in intact cells. Curr Biol. 6:1996;1664-1668.
    • (1996) Curr Biol , vol.6 , pp. 1664-1668
    • Stambolic, V.1    Laurent, R.2    Woodgett, J.R.3
  • 165
    • 0027761105 scopus 로고
    • Injection of the protein kinase inhibitor H7 into the A10 dopamine region blocks the acute responses to cocaine: Behavioral and in vivo microdialysis studies
    • Steketee J.D. Injection of the protein kinase inhibitor H7 into the A10 dopamine region blocks the acute responses to cocaine behavioral and in vivo microdialysis studies . Neuropharmacology. 32:1993;1289-1297.
    • (1993) Neuropharmacology , vol.32 , pp. 1289-1297
    • Steketee, J.D.1
  • 166
    • 0028568329 scopus 로고
    • Intra-A10 injection of H7 blocks the development of sensitization to cocaine
    • Steketee J.D. Intra-A10 injection of H7 blocks the development of sensitization to cocaine. Neuroreport. 30:1994;6:69-6:72.
    • (1994) Neuroreport , vol.30 , pp. 669-672
    • Steketee, J.D.1
  • 167
    • 0027465670 scopus 로고
    • Lithium enhances muscarinic receptor-stimulated CDP-diacylglycerol formation in inositol-depleted SK-N-SH neuroblastoma cells
    • Stubbs E.B., Agranoff B.W. Lithium enhances muscarinic receptor-stimulated CDP-diacylglycerol formation in inositol-depleted SK-N-SH neuroblastoma cells. J Neurochem. 60:1993;1292-1299.
    • (1993) J Neurochem , vol.60 , pp. 1292-1299
    • Stubbs, E.B.1    Agranoff, B.W.2
  • 168
    • 0026339062 scopus 로고
    • Risk of recurrence following discontinuation of lithium treatment in bipolar disorder
    • Suppes T., Baldessarini R.J., Faedda G.L., et al. Risk of recurrence following discontinuation of lithium treatment in bipolar disorder. Arch Gen Psychiatry. 48:1991;1082-1088.
    • (1991) Arch Gen Psychiatry , vol.48 , pp. 1082-1088
    • Suppes, T.1    Baldessarini, R.J.2    Faedda, G.L.3
  • 169
    • 0029053995 scopus 로고
    • Membrane association of the myristoylated alanine-rick C kinase substrate (MARCKS) protein. Mutational analysis provides evidence for complex interactions
    • Swierczynski S.L., Blackshear P.J. Membrane association of the myristoylated alanine-rick C kinase substrate (MARCKS) protein. Mutational analysis provides evidence for complex interactions. J Biol Chem. 270:1995;13436-13445.
    • (1995) J Biol Chem , vol.270 , pp. 13436-13445
    • Swierczynski, S.L.1    Blackshear, P.J.2
  • 170
    • 0025203976 scopus 로고
    • The role of G proteins in transmembrane signaling
    • Taylor C.W. The role of G proteins in transmembrane signaling. Biochem J. 272:1990;1-13.
    • (1990) Biochem J , vol.272 , pp. 1-13
    • Taylor, C.W.1
  • 171
    • 0031590702 scopus 로고    scopus 로고
    • Effect of lithium maintenance on suicidal behavior in major mood disorders
    • Tondo L., Jamison K.R., Baldessarini R.J. Effect of lithium maintenance on suicidal behavior in major mood disorders. Ann N Y Acad Sci. 836:1997;339-351.
    • (1997) Ann N Y Acad Sci , vol.836 , pp. 339-351
    • Tondo, L.1    Jamison, K.R.2    Baldessarini, R.J.3
  • 172
    • 0026536597 scopus 로고
    • Mania in association with hydrocortisone replacement for Addison's disease
    • Ur E., Turner T.H., Goodwin T.J., Grossman A., Besser G.M. Mania in association with hydrocortisone replacement for Addison's disease. Postgrad Med J. 68:1992;41-43.
    • (1992) Postgrad Med J , vol.68 , pp. 41-43
    • Ur, E.1    Turner, T.H.2    Goodwin, T.J.3    Grossman, A.4    Besser, G.M.5
  • 174
    • 0026053717 scopus 로고
    • Five-year mortality in lithium-treated manic-depressive patients
    • Vestergaard P., Aagaard J. Five-year mortality in lithium-treated manic-depressive patients. J Affect Disord. 21:1991;33-38.
    • (1991) J Affect Disord , vol.21 , pp. 33-38
    • Vestergaard, P.1    Aagaard, J.2
  • 175
    • 0029998294 scopus 로고    scopus 로고
    • Cellular phosphorylation of tau by GSK-3beta influences tau binding to microtubules and microtubule organization
    • Wagner U., Utton M., Gallo J.M., Miller C.C.J. Cellular phosphorylation of tau by GSK-3beta influences tau binding to microtubules and microtubule organization. J Cell Sci. 109:1996;1537-1543.
    • (1996) J Cell Sci , vol.109 , pp. 1537-1543
    • Wagner, U.1    Utton, M.2    Gallo, J.M.3    Miller, C.C.J.4
  • 176
    • 0030273260 scopus 로고    scopus 로고
    • Enhanced protein kinase C activity and translocation in bipolar affective disorder brains
    • Wang H., Friedman E. Enhanced protein kinase C activity and translocation in bipolar affective disorder brains. Biol Psychiatry. 40:1996;568-575.
    • (1996) Biol Psychiatry , vol.40 , pp. 568-575
    • Wang, H.1    Friedman, E.2
  • 177
    • 0024397923 scopus 로고
    • Lithium inhibition of protein kinase C activation-induced serotonin release
    • Wang H.Y., Friedman E. Lithium inhibition of protein kinase C activation-induced serotonin release. Psychopharmacology (Berlin). 99:1989;213-218.
    • (1989) Psychopharmacology (Berlin) , vol.99 , pp. 213-218
    • Wang, H.Y.1    Friedman, E.2
  • 178
    • 0033012183 scopus 로고    scopus 로고
    • Increased membrane associated protein kinase C activity and translocation in blood platelets from bipolar affective disorder patients
    • Wang H.Y., Markowitz P., Levinson D., Undie A.S., Friedman E. Increased membrane associated protein kinase C activity and translocation in blood platelets from bipolar affective disorder patients. J Psychiatric Res. 33:1999;171-179.
    • (1999) J Psychiatric Res , vol.33 , pp. 171-179
    • Wang, H.Y.1    Markowitz, P.2    Levinson, D.3    Undie, A.S.4    Friedman, E.5
  • 180
    • 0003474551 scopus 로고
    • Phosphorylation and associated translocation of the 87-kDa protein, a major protein kinase C substrate, in isolated nerve terminals
    • Wang J.K.T., Walaas S.I., Sihra T.S., Aderem A., Greengard P. Phosphorylation and associated translocation of the 87-kDa protein, a major protein kinase C substrate, in isolated nerve terminals. Proc Natl Acad Sci USA. 86:1989;2253-2256.
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 2253-2256
    • Wang, J.K.T.1    Walaas, S.I.2    Sihra, T.S.3    Aderem, A.4    Greengard, P.5
  • 181
    • 0030036555 scopus 로고    scopus 로고
    • Chronic lithium-induced down-regulation of MARCKS in immortalized hippocampal cells: Potentiation by muscarinic receptor activation
    • Watson D.G., Lenox R.H. Chronic lithium-induced down-regulation of MARCKS in immortalized hippocampal cells Potentiation by muscarinic receptor activation . J Neurochem. 67:1996;767-777.
    • (1996) J Neurochem , vol.67 , pp. 767-777
    • Watson, D.G.1    Lenox, R.H.2
  • 182
    • 0027944997 scopus 로고
    • Phorbol ester- And retinoic acid-induced regulation of the protein kinase C substrate MARCKS in immortalized hippocampal cells
    • Watson D.G., Wainer B.H., Lenox R.H. Phorbol ester- and retinoic acid-induced regulation of the protein kinase C substrate MARCKS in immortalized hippocampal cells. J Neurochem. 63:1994;1666-1674.
    • (1994) J Neurochem , vol.63 , pp. 1666-1674
    • Watson, D.G.1    Wainer, B.H.2    Lenox, R.H.3
  • 183
    • 0031981038 scopus 로고    scopus 로고
    • Sodium valproate down-regulates the myristoylated alanine-rich C kinase substrate (MARCKS) in immortalized hippocampal cells. A property of protein kinase C-mediated mood stabilizers
    • Watson D.G., Watterson J.M., Lenox R.H. Sodium valproate down-regulates the myristoylated alanine-rich C kinase substrate (MARCKS) in immortalized hippocampal cells. A property of protein kinase C-mediated mood stabilizers. J Pharmacol Exp Ther. 285:1998;307-316.
    • (1998) J Pharmacol Exp Ther , vol.285 , pp. 307-316
    • Watson, D.G.1    Watterson, J.M.2    Lenox, R.H.3
  • 184
    • 0023499777 scopus 로고
    • Can antidepressants cause mania and worsen the course of affective illness?
    • Wehr T.A., Goodwin F.K. Can antidepressants cause mania and worsen the course of affective illness? Am J Psychiatry. 144:1987;1403-1411.
    • (1987) Am J Psychiatry , vol.144 , pp. 1403-1411
    • Wehr, T.A.1    Goodwin, F.K.2
  • 185
    • 0028625596 scopus 로고
    • Caveats in the use of the kindling model of affective disorders
    • Weiss S.R., Post R.M. Caveats in the use of the kindling model of affective disorders. Toxicol Ind Health. 10:(4-5):1994;421-447.
    • (1994) Toxicol Ind Health , vol.10 , Issue.45 , pp. 421-447
    • Weiss, S.R.1    Post, R.M.2
  • 188
    • 0023655187 scopus 로고
    • Down-regulation of Protein kinase C is due to an increased rate of degradation
    • Young S., Parker P.J., Ullrich A., Stabel S. Down-regulation of Protein kinase C is due to an increased rate of degradation. Biochem J. 24:1987;775-779.
    • (1987) Biochem J , vol.24 , pp. 775-779
    • Young, S.1    Parker, P.J.2    Ullrich, A.3    Stabel, S.4
  • 189
    • 0032527821 scopus 로고    scopus 로고
    • Lithium stimulates gene expression through the AP-1 transcription factor pathway
    • Yuan P.X., Chen G., Manji H.K. Lithium stimulates gene expression through the AP-1 transcription factor pathway. Mol Brain Res. 58:1998;225-230.
    • (1998) Mol Brain Res , vol.58 , pp. 225-230
    • Yuan, P.X.1    Chen, G.2    Manji, H.K.3
  • 191
    • 0021985333 scopus 로고
    • Lithium induces corticotropin secretion and de-sensitization in cultured anterior pituitary cells
    • Zatz M., Reisine T.D. Lithium induces corticotropin secretion and de-sensitization in cultured anterior pituitary cells. Proc Natl Acad Sci USA. 82:1985;1286-1290.
    • (1985) Proc Natl Acad Sci USA , vol.82 , pp. 1286-1290
    • Zatz, M.1    Reisine, T.D.2
  • 192
    • 0032528853 scopus 로고    scopus 로고
    • Expression and regulation of the human dopamine transporter in a neuronal cell line
    • Zhang L., Elmer L.W., Little K.Y. Expression and regulation of the human dopamine transporter in a neuronal cell line. Brain Res Mol Brain Res. 59:1998;66-73.
    • (1998) Brain Res Mol Brain Res , vol.59 , pp. 66-73
    • Zhang, L.1    Elmer, L.W.2    Little, K.Y.3


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