The Mood Stabilizer Valproic Acid Activates Mitogen-activated Protein Kinases and Promotes Neurite Growth

Journal of Biological Chemistry

Volumn 276, Issue 34, 2001, Pages 31674-31683

  Yuan, Pei Xiong ^a   Huang, Li Dong ^a   Jiang, Yi Ming ^a   Gutkind, J Silvio ^b   Manji, Husseini K ^a,c   Chen, Guang ^a,c  

^a WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NATIONAL INSTITUTE OF DENTAL AND CRANIOFACIAL RESEARCH   (United States)

^c NATIONAL INSTITUTE OF MENTAL HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BRAIN; CHEMICAL ACTIVATION; DNA; ENZYME INHIBITION; ENZYMES; GENES; LITHIUM;

GENE EXPRESSION; NEURITE GROWTH;

BIOCHEMISTRY;

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; LITHIUM; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE; NEUROTROPHIN; NORADRENALIN; PROTEIN BCL 2; RAF PROTEIN; RAS PROTEIN; TRANSCRIPTION FACTOR AP 1; VALPROIC ACID; ENZYME INHIBITOR; FLAVONOID; NEUROMODULIN; ONCOPROTEIN; PRIMER DNA; PROTEIN BAX;

ARTICLE; CELL DIFFERENTIATION; CELL SURVIVAL; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA BINDING; GENE EXPRESSION; HUMAN; HUMAN CELL; LEARNING; MEMORY; NERVE CELL PLASTICITY; NERVE FIBER GROWTH; NEUROBLASTOMA CELL; NORADRENALIN RELEASE; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; TRANSACTIVATION; CELL CULTURE; CULTURE MEDIUM; DRUG ANTAGONISM; DRUG EFFECT; ENZYME ACTIVATION; METABOLISM; NEURITE; NUCLEOTIDE SEQUENCE; PHOSPHORYLATION;

BASE SEQUENCE; BCL-2-ASSOCIATED X PROTEIN; CELL SURVIVAL; CULTURE MEDIA, SERUM-FREE; DNA PRIMERS; ENZYME ACTIVATION; ENZYME INHIBITORS; FLAVONOIDS; GAP-43 PROTEIN; HUMANS; MITOGEN-ACTIVATED PROTEIN KINASES; NEURITES; NOREPINEPHRINE; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2; TUMOR CELLS, CULTURED; VALPROIC ACID;

EID: 0035943699     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M104309200     Document Type: Article

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