Valproate inhibits oxidative damage to lipid and protein in primary cultured rat cerebrocortical cells

Neuroscience

Volumn 116, Issue 2, 2003, Pages 485-489

  Wang, J F ^a   Azzam, J E ^a   Young, L T ^a  

^a MCMASTER UNIVERSITY   (Canada)

Author keywords

Glucose regulated protein; Lipid peroxidation; Mood stabilizing drug; Protein oxidation; Reactive oxygen species

Indexed keywords

CYTOCHROME C; FERRIC CHLORIDE; HEAT SHOCK PROTEIN; LIPID; PROTEIN BCL 2; VALPROIC ACID;

ANIMAL CELL; ARTICLE; BRAIN CELL; BRAIN CORTEX; BRAIN MITOCHONDRION; CELL CULTURE; CELL PROTECTION; CONTROLLED STUDY; DRUG ACTIVITY; DRUG EFFECT; LIPID PEROXIDATION; NEUROPROTECTION; NONHUMAN; OXIDATION; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FOLDING; PROTEIN FUNCTION; PROTEIN SECRETION; PROTEIN STABILITY; RAT;

EID: 0037474040     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0306-4522(02)00655-3     Document Type: Article

References (49)

1. Ames B.N., Shigenaga M.K., Hagen T.M. Mitochondrial decay in aging. Biochem Biophys Acta. 1271:1995;165-170.
2. Andoh T., Lee S.Y., Chiueh C.C. Preconditioning regulation of bcl-2 and p66shc by human NOS1 enhances tolerance to oxidative stress. FASEB J. 14:2000;2144-2146.
3. Andrieu-Abadie N., Gouaze V.V., Salvayre R., Levade T. Ceramide in apoptosis signaling relationship with oxidative stress . Free Radic Biol Med. 31:2001;717-728.
4. Bartlett W.P., Banker G.A. An electron microscopic study of the development of axons and dendrites by hippocampal neurons in culture. I. Cells which develop without intercellular contacts. J Neurosci. 4:1984;1944-1953.
5. Benowitzv L.I., Routtenberg A. GAP-43 an intrinsic determinant of neuronal development and plasticity . Trends Neurosci. 1997;84-91.
6. Bogdanov M.B., Ferrante R.J., Mueller G., Ramos L.E., Martinou J.C., Beal M.F. Oxidative stress is attenuated in mice overexpressing BCL-2. Neurosci Lett. 262:1999;33-36.
7. Bowden C.L. Role of newer medications for bipolar disorder. J Clin Psychopharmacol. 16:(suppl):1996;42S-45S.
8. Bown C., Wang J.F., Young L.T. Increased expression of endoplasmic reticulum stress proteins following chronic valproate treatment of rat C6 glioma cells. Neuropharmacol. 39:2000;2162-2169.
9. Bradford M.M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem. 72:1976;248-252.
10. Brewer G.J. Regeneration and proliferation of embryonic and adult rat hippocampal neurons in culture. Exp Neurol. 159:1999;237-247.
11. Brewer G.J., Torricelli J.R., Evege E.K., Price P.J. Optimized survival of hippocampal neurons in B27-supplemented Neurobasal, a new serum-free medium combination. J Neurosci Res. 35:1993;567-576.
12. Cadenas E., Davies K.J. Mitochondrial free radical generation, oxidative stress, and aging. Free Radic Biol Med. 3-4:2000;222-230.
13. Chance B., Sies H., Boveris A. Hydroperoxide metabolism in mammalian organs. Physiol Rev. 1979;527-605.
14. Chiaramonte R., Bartolini E., Riso P., Calzavara E., Erba D., Testolin G., Comi P., Sherbet G.V. Oxidative stress signalling in the apoptosis of Jurkat T-lymphocytes. J Cell Biochem. 82:2001;437-444.
15. Chen B., Wang J.F., Young L.T. Chronic valproate increases expression of endoplasmic reticulum stress proteins in rat cerebral cortex and hippocampus. Biol Psychiatry. 48:2000;658-664.
16. Chen G., Zeng W.Z., Yuan P.X., Huang L.D., Jiang Y.M., Zhao Z.H., Manji H.K. The mood-stabilizing agents lithium and valproate robustly increase the levels of the neuroprotective protein bcl-2 in the CNS. J Neurochem. 72:1999;879-882.
17. Dong G.X., Singh D.K., Dendle P., Prasad R.M. Regional expression of Bcl-2 mRNA and mitochondrial cytochrome c release after experimental brain injury in the rat. Brain Res. 903:2001;45-52.
18. Fernandez-Checa J.C., Garcia-Ruiz C., Colell A., Morales A., Mari M., Miranda M., Ardite E. Oxidative stress Role of mitochondria and protection by glutathione . Biofactors. 8:1998;7-11.
19. Fridovich I. Biological effects of the superoxide radical. Arch Biochem Biophys. 247:1986;1-11.
20. Herken H., Uz E., Ozyurt H., Sogut S., Virit O., Akyol O. Evidence that the activities of erythrocyte free radical scavenging enzymes and the products of lipid peroxidation are increased in different forms of schizophrenia. Mol Psychiatry. 6:2001;66-73.
21. Hyman S.E., Nestler E.J. Initiation and adaptation a paradigm for understanding psychotropic drug action . Am J Psychiatry. 153:1996;151-162.
22. Kane D.J., Sarafian T.A., Anton R., Hahn H., Gralla E.B., Valentine J.S., Ord T., Bredesen D.E. Bcl-2 inhibition of neural death Decreased generation of reactive oxygen species . Science. 262:1993;1274-1277.
23. Kowaltowski A.J., Vercesi A.E., Fiskum G. Bcl-2 prevents mitochondrial permeability transition and cytochrome c release via maintenance of reduced pyridine nucleotides. Cell Death Differ. 7:2000;903-910.
24. Lee J., Bruce-Keller A.J., Kruman Y., Chan S.L., Mattson M.P. 2-Deoxy-D-glucose protects hippocampal neurons against excitotoxic and oxidative injury Evidence for the involvement of stress proteins . J Neurosci Res. 57:1999;48-61.
25. Li R., El-Mallahk R.S. A novel evidence of different mechanisms of lithium and valproate neuroprotective action on human SY5Y neuroblastoma cells Caspase-3 dependency . Neurosci Lett. 2000;147-150.
26. Little E., Ramakrishnan M., Roy B., Gazit G., Lee A.S. The glucose-regulated proteins (GRP78 and GRP94) Functions, gene regulation, and applications . Crit Rev Eukaryotic Gene Expression. 4:1994;1-18.
27. Liu H., Miller E., van de Water B., Stevens J.L. Endoplasmic reticulum stress proteins block oxidant-induced Ca2+ increases and cell death. J Biol Chem. 273:1998;12858-12862.
28. Mahadik S.P., Evans D., Lal H. Oxidative stress and role of antioxidant and omega-3 essential fatty acid supplementation in schizophrenia. Biol Psychiatry. 25:2001;463-493.
29. Manji H.K., Moore G.J., Chen G. Lithium at 50 Have the neuroprotective effects of this unique cation been overlooked? Biol Psychiatry. 46:1999;929-940.
30. Marnett L.J. Oxyradicals and DNA damage. Carcinogenesis. 21:2000;361-370.
31. McCord J.M., Fridovich I. Superoxide dismutase The first twenty years, 1968-1988 . Free Radic Biol Med. 5:1988;363-369.
32. McElroy S.L., Keck P.E. Jr., Pope H.G. Jr., Hudson J.I. Valproate in the treatment of bipolar disorder Literature review and clinical guidelines . J Clin Psychopharmacol. 12:(suppl):1992;42S-51S.
33. Nigam S.K., Goldberg A.L., Ho S., Ghode M.F., Bush K.T., Sherman M.Y.U. A set of endoplasmic reticulum proteins possessing properties of molecular chaperones includes CA2+ binding proteins and member of the thioredoxin superfamily. J Biol Chem. 269:1994;1744-1749.
34. Nonaka S., Katsube N., Chuang D.M. Lithium protects rat cerebellar granule cells against apoptosis induced by anticonvulsants, phenytoin and carbamazepine. J Pharmacol Exp Ther. 286:1998;39-47.
35. Nonaka S., Hough C.J., Chuang D.M. Chronic lithium treatment robustly protects neurons in the central nervous system against excitotoxicity by inhibiting N-methyl-D-aspartate receptor-mediated calcium influx. Proc Natl Acad Sci USA. 95:1998;2642-2647.
36. Ongur D., Drevets W.C., Price J.L. Glial reduction in the subgenual prefrontal cortex in mood disorders. Proc Natl Acad Sci USA. 95:1998;13290-13295.
37. Post R.M. Transduction of psychosocial stress into the neurobiology of recurrent affective disorder. Am J Psychiatry. 149:1992;999-1010.
38. See V., Loeffler J.P. Oxidative stress induces neuronal death by recruiting a protease and phosphatase-gated mechanism. J Biol Chem. 276:2001;35049-35059.
39. Skaper S.D., Floreani M., Ceccon M., Facci L., Giusti P. Excitotoxicity, oxidative stress, and the neuroprotective potential of melatonin. Ann NY Acad Sci. 890:1999;107-118.
40. Soares J.C., Mann J.J. The anatomy of mood disorders - review of structural neuroimaging studies. Biol Psychiatry. 41:1997;86-106.
41. Stadtman E.R. Protein oxidation and aging. Science. 257:1992;1220-1224.
42. Sun F., Hamagawa E., Tsutsui C., Ono Y., Ogiri Y., Kojo S. Evaluation of oxidative stress during apoptosis and necrosis caused by carbon tetrachloride in rat liver. Biochem Biophys Acta. 1535:2001;186-191.
43. Turrens J.F., Boveris A. Generation of superoxide anion by the NADH dehydrogenase of bovine heart mitochondria. Biochem J. 191:1980;421-427.
44. Tyurina Y.Y., Tyurin V.A., Carta G., Quinn P.J., Schor N.F., Kagan V.E. Direct evidence for antioxidant effect of Bcl-2 in PC12 rat pheochromocytoma cells. Arch Biochem Biophys. 344:1997;413-423.
45. Vawter M.P., Freed W.J., Kleinman J.E. Neuropathology of bipolar disorder. Biol Psychiatry. 48:2000;486-504.
46. Wang J.F., Bown C., Young L.T. Differential display PCR reveals novel targets for the mood stabilizing drug valproate including the molecular chaperone GRP78. Mol Pharmacol. 55:1999;521-527.
47. Wooden S.K., Li L.J., Navarro D., Qadri I., Pereira L., Lee A.S. Transactivation of the GRP78 promoter by malfolded proteins, glycosylation block, and calcium ionophore is mediated through a proximal region containing a CCAAT motif which interacts with CTF/NF-I. Mol Cell Biol. 11:1991;5612-5623.
48. Yuan P.X., Huang L.D., Jiang Y.M., Gutkind J.S., Manji H.K., Chen G. The mood stabilizer valproic acid activates mitogen-activated protein kinases and promotes neurite growth. J Biol Chem. 276:2001;31674-31683.
49. Yu Z., Luo H., Fu W., Mattson M.P. The endoplasmic reticulum stress-responsive protein GRP78 protects neurons against excitotoxicity and apoptosis Suppression of oxidative stress and stabilization of calcium homeostasis . Exp Neurol. 155:1999;302-314.