Glycogen synthase kinase-3β haploinsufficiency mimics the behavioral and molecular effects of lithium

Journal of Neuroscience

Volumn 24, Issue 30, 2004, Pages 6791-6798

  O'Brien, W Timothy ^a   Harper, Amber DeAra ^a   Jové, Fernando ^a   Woodgett, James R ^b   Maretto, Silvia ^c   Piccolo, Stefano ^c   Klein, Peter S ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b PRINCESS MARGARET HOSPITAL   (Canada)

^c UNIVERSITY OF PADOVA   (Italy)

Author keywords

Amygdala; Behavior; Bipolar disorder; Forced swim test; Glycogen synthase kinase 3 ; GSK 3; Lithium; Mouse; T cell factor (TCF); Wnt

Indexed keywords

GLYCOGEN SYNTHASE KINASE 3BETA; LITHIUM; T CELL FACTOR PROTEIN; WNT1 PROTEIN;

AMYGDALOID NUCLEUS; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BIPOLAR DISORDER; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; ENZYME INHIBITION; FORCED SWIMMING TEST; GENE EXPRESSION REGULATION; HAPLOTYPE; HETEROZYGOSITY; MOLECULAR MIMICRY; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; BEHAVIOR, ANIMAL; BETA CATENIN; BRAIN; BRAIN CHEMISTRY; CYTOSKELETAL PROTEINS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; EXPLORATORY BEHAVIOR; FEMALE; GLYCOGEN SYNTHASE KINASE 3; GROOMING; HABITUATION, PSYCHOPHYSIOLOGIC; HETEROZYGOTE; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; LITHIUM CHLORIDE; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, MUTANT STRAINS; MOTOR ACTIVITY; NERVE TISSUE PROTEINS; PSYCHOTROPIC DRUGS; RANDOM ALLOCATION; SOCIAL BEHAVIOR; STARTLE REACTION; SWIMMING; TRANS-ACTIVATORS; TRANSCRIPTION, GENETIC; WNT PROTEINS;

EID: 3342955475     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.4753-03.2004     Document Type: Article

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