Oxidative demethylation by Escherichia coli AlkB directly reverts DNA base damage

Nature

Volumn 419, Issue 6903, 2002, Pages 174-178

  Trewick, Sarah C ^a   Henshaw, Timothy F ^b   Hausinger, Robert P ^b   Lindahl, Tomas ^a,b   Sedgwick, Barbara ^a  

^a IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

^b MICHIGAN STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALKYLATION; CELLS; DNA; MUTAGENESIS;

OXIDATIVE DEMETHYLATION;

ESCHERICHIA COLI;

1 METHYLADENINE; 2 OXOGLUTARIC ACID; 3 METHYLCYTOSINE; BACTERIAL DNA; CYTOSINE DERIVATIVE; DNA BINDING PROTEIN; FORMALDEHYDE; PROTEIN ALKB; UNCLASSIFIED DRUG;

DNA;

ARTICLE; DEMETHYLATION; DNA DAMAGE; DNA METHYLATION; DNA REPAIR; ENZYME ACTIVITY; ESCHERICHIA COLI; NONHUMAN; PRIORITY JOURNAL; REACTION ANALYSIS;

ADENINE; ALKYLATION; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CYTOSINE; DNA DAMAGE; DNA METHYLATION; DNA REPAIR; DNA, BACTERIAL; DNA, SINGLE-STRANDED; EDETIC ACID; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; ETHANOL; FORMALDEHYDE; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; HYDROXYLATION; MIXED FUNCTION OXYGENASES; MUTATION; OXIDATION-REDUCTION; OXYGEN;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI;

EID: 0037068446     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/nature00908     Document Type: Article

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