Structural basis for recognition and repair of the endogenous mutagen 8-oxoguanine in DNA

Nature

Volumn 403, Issue 6772, 2000, Pages 859-866

  Bruner, Steven D ^a   Norman, Derek P G ^a   Verdine, Gregory L ^a  

^a HARVARD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

8 HYDROXYGUANINE; DNA; DNA GLYCOSYLTRANSFERASE; MUTAGENIC AGENT;

ARTICLE; BASE MISPAIRING; CARCINOGENESIS; CATALYSIS; CRYSTAL STRUCTURE; DNA CLEAVAGE; DNA DAMAGE; DNA REPLICATION; DNA STRUCTURE; EXCISION REPAIR; GENETIC POLYMORPHISM; HUMAN; MOLECULAR RECOGNITION; NUCLEIC ACID BASE SUBSTITUTION; PRIORITY JOURNAL; SOMATIC MUTATION; X RAY CRYSTALLOGRAPHY;

AMINO ACID SEQUENCE; CATALYSIS; CATALYTIC DOMAIN; CLONING, MOLECULAR; CRYSTALLOGRAPHY, X-RAY; CYTOSINE; DNA; DNA REPAIR; DNA-FORMAMIDOPYRIMIDINE GLYCOSYLASE; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; GUANINE; HUMANS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENS; MUTATION; N-GLYCOSYL HYDROLASES; NUCLEIC ACID CONFORMATION; PROTEIN BINDING; PROTEIN CONFORMATION; SEQUENCE ALIGNMENT; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0034708226     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/35002510     Document Type: Article

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