hUNG2 is the major repair enzyme for removal of uracil from U:A matches, U:G mismatches, and U in single-stranded DNA, with hSMUG1 as a broad specificity backup

Journal of Biological Chemistry

Volumn 277, Issue 42, 2002, Pages 39926-39936

  Kavli, Bodil ^a   Sundheim, Ottar ^a   Akbari, Mansour ^a   Otterlei, Marit ^a   Nilsen, Hilde ^a   Skorpen, Frank ^a   Aas, Per Arne ^a   Hagen, Lars ^a   Krokan, Hans E ^a   Slupphaug, Geir ^a,b  

^a NORWEGIAN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Norway)

^b IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODIES; CELLS; DISSOCIATION; DNA; PHYSIOLOGY;

PLASMIDS;

ENZYMES;

3,N4 ETHENOCYTOSINE; 5 HYDROXYMETHYLURACIL; CYTOSINE DERIVATIVE; DNA GLYCOSYLTRANSFERASE; MAGNESIUM ION; PROTEIN; PROTEIN APE1; PROTEIN HSMUG1; PROTEIN HUNG2; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG; URACIL;

ARTICLE; BINDING SITE; CELL CYCLE S PHASE; CHROMATIN; CONTROLLED STUDY; DEAMINATION; DISSOCIATION; DNA SEQUENCE; ENZYME ACTIVITY; ENZYME SPECIFICITY; EXCISION REPAIR; EXPRESSED SEQUENCE TAG; HUMAN; HUMAN CELL; MISMATCH REPAIR; MOLECULAR MODEL; NUCLEIC ACID BASE SUBSTITUTION; NUCLEOLUS; PLASMID; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PROCESSING;

ANIMALS; BINDING SITES; CATTLE; CELL CYCLE; CELL NUCLEUS; CHROMATIN; CLONING, MOLECULAR; DNA GLYCOSYLASES; DNA REPAIR; DNA, SINGLE-STRANDED; DOSE-RESPONSE RELATIONSHIP, DRUG; HELA CELLS; HUMANS; IMMUNOGLOBULIN G; KINETICS; MAGNESIUM CHLORIDE; MICROSCOPY, FLUORESCENCE; MODELS, BIOLOGICAL; N-GLYCOSYL HYDROLASES; POLYMERASE CHAIN REACTION; PROMOTER REGIONS (GENETICS); PROTEIN BINDING; RECOMBINANT PROTEINS; SALTS; SUBSTRATE SPECIFICITY; TUMOR CELLS, CULTURED; URACIL; URACIL-DNA GLYCOSIDASE;

EID: 18644363009     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M207107200     Document Type: Article

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