Structural basis for removal of adenine mispaired with 8-oxoguanine by MutY adenine DNA glycosylase

Nature Materials

Volumn 427, Issue 6975, 2004, Pages 652-656

  Fromme, J Christopher ^a   Banerjee, Anirban ^b   Huang, Susan J ^a   Verdine, Gregory L ^a,b  

^a HARVARD UNIVERSITY   (United States)

^b HARVARD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIA; CROSSLINKING; CRYSTAL STRUCTURE; DNA; ENZYMES; GENES;

GENOTOXIC PRODUCTS; MUTAGENIC LESIONS;

GENETIC ENGINEERING;

8 HYDROXYGUANINE; ADENINE; CYTOSINE; DNA ADENINE GLYCOSYLASE; DNA GLYCOSYLASE MUTY; DNA GLYCOSYLTRANSFERASE; DNA POLYMERASE; GUANINE; MYH PROTEIN; UNCLASSIFIED DRUG;

DNA;

ARTICLE; BASE MISPAIRING; CROSS LINKING; CRYSTAL STRUCTURE; DISULFIDE BOND; DNA BASE COMPOSITION; DNA PROTEIN COMPLEX; DNA REPAIR; DNA STRUCTURE; EXCISION REPAIR; GENE INSERTION; GENE MUTATION; GENETIC CONSERVATION; GENOTOXICITY; GEOBACILLUS STEAROTHERMOPHILUS; MOLECULAR RECOGNITION; NONHUMAN; OXIDATION; PRIORITY JOURNAL;

ADENINE; BACILLUS STEAROTHERMOPHILUS; BASE PAIRING; BINDING SITES; CATALYSIS; CROSS-LINKING REAGENTS; CRYSTALLOGRAPHY, X-RAY; DISULFIDES; DNA; DNA GLYCOSYLASES; GUANINE; MODELS, MOLECULAR; N-GLYCOSYL HYDROLASES; PROTEIN CONFORMATION; STRUCTURE-ACTIVITY RELATIONSHIP;

GEOBACILLUS STEAROTHERMOPHILUS;

EID: 1342304229     PISSN: 14761122     EISSN: 14764660     Source Type: Journal    
DOI: 10.1038/nature02306     Document Type: Letter

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