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Volumn 57, Issue 5, 2005, Pages 781-802

Approaches to improving the kinetics of adenovirus-delivered genes and gene products

Author keywords

Biodistribution; Cationic liposome; Helper dependent; Immunogenic toxicities; In cis acting element; Integration; PEGylation; Regulatable expression; Targeting

Indexed keywords

DRUG PRODUCTS; REACTION KINETICS; TOXICITY; VECTORS; VIRUSES;

EID: 14844283783     PISSN: 0169409X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.addr.2004.12.010     Document Type: Review
Times cited : (38)

References (188)
  • 1
    • 0024499847 scopus 로고
    • The orientation of the adenovirus fiber and its anchor domain identified through molecular mimicry
    • J.M. Weber, B.G. Talbot, and L. Delorme The orientation of the adenovirus fiber and its anchor domain identified through molecular mimicry Virology 168 1989 180 182
    • (1989) Virology , vol.168 , pp. 180-182
    • Weber, J.M.1    Talbot, B.G.2    Delorme, L.3
  • 2
    • 0021092717 scopus 로고
    • Evidence for a repeating cross-beta sheet structure in the adenovirus fibre
    • N.M. Green, N.G. Wrigley, W.C. Russell, S.R. Martin, and A.D. McLachlan Evidence for a repeating cross-beta sheet structure in the adenovirus fibre EMBO J. 2 1983 1357 1365
    • (1983) EMBO J. , vol.2 , pp. 1357-1365
    • Green, N.M.1    Wrigley, N.G.2    Russell, W.C.3    Martin, S.R.4    McLachlan, A.D.5
  • 3
    • 0028283086 scopus 로고
    • Characterization of the knob domain of the adenovirus type 5 fiber protein expressed in Escherichia coli
    • L.J. Henry, D. Xia, M.E. Wilke, J. Deisenhofer, and R.D. Gerard Characterization of the knob domain of the adenovirus type 5 fiber protein expressed in Escherichia coli J. Virol. 68 1994 5239 5246
    • (1994) J. Virol. , vol.68 , pp. 5239-5246
    • Henry, L.J.1    Xia, D.2    Wilke, M.E.3    Deisenhofer, J.4    Gerard, R.D.5
  • 5
    • 0017710978 scopus 로고
    • Characteristics of a human cell line transformed by DNA from human adenovirus type 5
    • F.L. Graham, J. Smiley, W.C. Russell, and R. Nairn Characteristics of a human cell line transformed by DNA from human adenovirus type 5 J. Gen. Virol. 36 1977 59 74
    • (1977) J. Gen. Virol. , vol.36 , pp. 59-74
    • Graham, F.L.1    Smiley, J.2    Russell, W.C.3    Nairn, R.4
  • 8
    • 0028559768 scopus 로고
    • An efficient and flexible system for construction of adenovirus vectors with insertions or deletions in early regions 1 and 3
    • A.J. Bett, W. Haddara, L. Prevec, and F.L. Graham An efficient and flexible system for construction of adenovirus vectors with insertions or deletions in early regions 1 and 3 Proc. Natl. Acad. Sci. U. S. A. 91 1994 8802 8806
    • (1994) Proc. Natl. Acad. Sci. U. S. A. , vol.91 , pp. 8802-8806
    • Bett, A.J.1    Haddara, W.2    Prevec, L.3    Graham, F.L.4
  • 9
    • 0027260609 scopus 로고
    • Packaging capacity and stability of human adenovirus type 5 vectors
    • A.J. Bett, L. Prevec, and F.L. Graham Packaging capacity and stability of human adenovirus type 5 vectors J. Virol. 67 1993 5911 5921
    • (1993) J. Virol. , vol.67 , pp. 5911-5921
    • Bett, A.J.1    Prevec, L.2    Graham, F.L.3
  • 11
    • 0030915715 scopus 로고    scopus 로고
    • HCAR and MCAR: The human and mouse cellular receptors for subgroup C adenoviruses and group B coxsackieviruses
    • R.P. Tomko, R. Xu, and L. Philipson HCAR and MCAR: the human and mouse cellular receptors for subgroup C adenoviruses and group B coxsackieviruses Proc. Natl. Acad. Sci. U. S. A. 94 1997 3352 3356
    • (1997) Proc. Natl. Acad. Sci. U. S. A. , vol.94 , pp. 3352-3356
    • Tomko, R.P.1    Xu, R.2    Philipson, L.3
  • 12
    • 0031666742 scopus 로고    scopus 로고
    • The coxsackievirus-adenovirus receptor protein can function as a cellular attachment protein for adenovirus serotypes from subgroups A, C, D, E, and F
    • P.W. Roelvink, A. Lizonova, J.G. Lee, Y. Li, J.M. Bergelson, R.W. Finberg, D.E. Brough, I. Kovesdi, and T.J. Wickham The coxsackievirus-adenovirus receptor protein can function as a cellular attachment protein for adenovirus serotypes from subgroups A, C, D, E, and F J. Virol. 72 1998 7909 7915
    • (1998) J. Virol. , vol.72 , pp. 7909-7915
    • Roelvink, P.W.1    Lizonova, A.2    Lee, J.G.3    Li, Y.4    Bergelson, J.M.5    Finberg, R.W.6    Brough, D.E.7    Kovesdi, I.8    Wickham, T.J.9
  • 13
    • 0027166647 scopus 로고
    • Integrins αvβ3 and αvβ5 promote adenovirus internalization but not virus attachment
    • T.J. Wickham, P. Mathias, D.A. Cheresh, and G.R. Nemerow Integrins αvβ3 and αvβ5 promote adenovirus internalization but not virus attachment Cell 73 1993 309 319
    • (1993) Cell , vol.73 , pp. 309-319
    • Wickham, T.J.1    Mathias, P.2    Cheresh, D.A.3    Nemerow, G.R.4
  • 14
    • 0030610717 scopus 로고    scopus 로고
    • Integrin alpha5beta1-mediated adenovirus infection is enhanced by the integrin-activating antibody TS2/16
    • E. Davison, R.M. Diaz, I.R. Hart, G. Santis, and J.F. Marshall Integrin alpha5beta1-mediated adenovirus infection is enhanced by the integrin-activating antibody TS2/16 J. Virol. 71 1997 6204 6207
    • (1997) J. Virol. , vol.71 , pp. 6204-6207
    • Davison, E.1    Diaz, R.M.2    Hart, I.R.3    Santis, G.4    Marshall, J.F.5
  • 16
    • 0034890820 scopus 로고    scopus 로고
    • Heparan sulfate glycosaminoglycans are receptors sufficient to mediate the initial binding of adenovirus types 2 and 5
    • M.C. Dechecchi, P. Melotti, A. Bonizzato, M. Santacatterina, M. Chilosi, and G. Cabrini Heparan sulfate glycosaminoglycans are receptors sufficient to mediate the initial binding of adenovirus types 2 and 5 J. Virol. 75 2001 8772 8780
    • (2001) J. Virol. , vol.75 , pp. 8772-8780
    • Dechecchi, M.C.1    Melotti, P.2    Bonizzato, A.3    Santacatterina, M.4    Chilosi, M.5    Cabrini, G.6
  • 17
    • 0021170531 scopus 로고
    • Role of a low-pH environment in adenovirus enhancement of the toxicity of a Pseudomonas exotoxin-epidermal growth factor conjugate
    • P. Seth, D.J. Fitzgerald, M.C. Willingham, and I. Pastan Role of a low-pH environment in adenovirus enhancement of the toxicity of a Pseudomonas exotoxin-epidermal growth factor conjugate J. Virol. 51 1984 650 655
    • (1984) J. Virol. , vol.51 , pp. 650-655
    • Seth, P.1    Fitzgerald, D.J.2    Willingham, M.C.3    Pastan, I.4
  • 18
    • 0027496645 scopus 로고
    • Stepwise dismantling of adenovirus 2 during entry into cells
    • U.F. Greber, M. Willetts, P. Webster, and A. Helenius Stepwise dismantling of adenovirus 2 during entry into cells Cell 75 1993 477 486
    • (1993) Cell , vol.75 , pp. 477-486
    • Greber, U.F.1    Willetts, M.2    Webster, P.3    Helenius, A.4
  • 19
    • 0033134604 scopus 로고    scopus 로고
    • Angiogenesis and vasculogenesis as therapeutic strategies for postnatal neovascularization
    • J.M. Isner, and T. Asahara Angiogenesis and vasculogenesis as therapeutic strategies for postnatal neovascularization J. Clin. Invest. 103 1999 1231 1236
    • (1999) J. Clin. Invest. , vol.103 , pp. 1231-1236
    • Isner, J.M.1    Asahara, T.2
  • 20
    • 0037049981 scopus 로고    scopus 로고
    • Myocardial gene therapy
    • J.M. Isner Myocardial gene therapy Nature 415 2002 234 239
    • (2002) Nature , vol.415 , pp. 234-239
    • Isner, J.M.1
  • 21
    • 0033926002 scopus 로고    scopus 로고
    • Replicative adenoviruses for cancer therapy
    • R. Alemany, C. Balague, and D.T. Curiel Replicative adenoviruses for cancer therapy Nat. Biotechnol. 18 2000 723 727
    • (2000) Nat. Biotechnol. , vol.18 , pp. 723-727
    • Alemany, R.1    Balague, C.2    Curiel, D.T.3
  • 22
    • 0037790710 scopus 로고    scopus 로고
    • Molecular basis of the inflammatory response to adenovirus vectors
    • Q. Liu, and D.A. Muruve Molecular basis of the inflammatory response to adenovirus vectors Gene Ther. 10 2003 935 940
    • (2003) Gene Ther. , vol.10 , pp. 935-940
    • Liu, Q.1    Muruve, D.A.2
  • 23
    • 0038805302 scopus 로고    scopus 로고
    • Immunity to adenovirus and adeno-associated viral vectors: Implications for gene therapy
    • K. Jooss, and N. Chirmule Immunity to adenovirus and adeno-associated viral vectors: implications for gene therapy Gene Ther. 10 2003 955 963
    • (2003) Gene Ther. , vol.10 , pp. 955-963
    • Jooss, K.1    Chirmule, N.2
  • 24
    • 0038128343 scopus 로고    scopus 로고
    • Adaptive and innate immune responses to gene transfer vectors: Role of cytokines and chemokines in vector function
    • D. Chen, B. Murphy, R. Sung, and J.S. Bromberg Adaptive and innate immune responses to gene transfer vectors: role of cytokines and chemokines in vector function Gene Ther. 10 2003 991 998
    • (2003) Gene Ther. , vol.10 , pp. 991-998
    • Chen, D.1    Murphy, B.2    Sung, R.3    Bromberg, J.S.4
  • 25
    • 0031887537 scopus 로고    scopus 로고
    • High adenoviral loads stimulate NF kappaB-dependent gene expression in human vascular smooth muscle cells
    • G.J. Clesham, P.J. Adam, D. Proudfoot, P.D. Flynn, S. Efstathiou, and P.L. Weissberg High adenoviral loads stimulate NF kappaB-dependent gene expression in human vascular smooth muscle cells Gene Ther. 5 1998 174 180
    • (1998) Gene Ther. , vol.5 , pp. 174-180
    • Clesham, G.J.1    Adam, P.J.2    Proudfoot, D.3    Flynn, P.D.4    Efstathiou, S.5    Weissberg, P.L.6
  • 26
    • 0030756389 scopus 로고    scopus 로고
    • The role of Kupffer cell activation and viral gene expression in early liver toxicity after infusion of recombinant adenovirus vectors
    • A. Lieber, C.-Y. He, L. Meuse, D. Schowalter, I. Kirillova, B. Winther, and M.A. Kay The role of Kupffer cell activation and viral gene expression in early liver toxicity after infusion of recombinant adenovirus vectors J. Virol. 71 1997 8798 8807
    • (1997) J. Virol. , vol.71 , pp. 8798-8807
    • Lieber, A.1    He, C.-Y.2    Meuse, L.3    Schowalter, D.4    Kirillova, I.5    Winther, B.6    Kay, M.A.7
  • 28
    • 0034986416 scopus 로고    scopus 로고
    • Acute cytokine response to systemic adenoviral vectors in mice is mediated by dendritic cells and macrophages
    • Y. Zhang, N. Chirmule, G.P. Gao, R. Qian, M. Croyle, B. Joshi, J. Tazelaar, and J.M. Wilson Acute cytokine response to systemic adenoviral vectors in mice is mediated by dendritic cells and macrophages Molec. Ther. 3 2001 697 707
    • (2001) Molec. Ther. , vol.3 , pp. 697-707
    • Zhang, Y.1    Chirmule, N.2    Gao, G.P.3    Qian, R.4    Croyle, M.5    Joshi, B.6    Tazelaar, J.7    Wilson, J.M.8
  • 30
    • 0028107757 scopus 로고
    • Regulation of TNF-mediated cell death and inflammation by human adenoviruses
    • L.R. Gooding Regulation of TNF-mediated cell death and inflammation by human adenoviruses Infect. Agents Dis. 3 1994 106 115
    • (1994) Infect. Agents Dis. , vol.3 , pp. 106-115
    • Gooding, L.R.1
  • 31
    • 0034986065 scopus 로고    scopus 로고
    • Acute direct adenoviral vector cytotoxicity and chronic, but not acute, inflammatory responses correlate with decreased vector-mediated transgene expression in the brain
    • C.E. Thomas, D. Birkett, I. Anozie, M.G. Castro, and P.R. Lowenstein Acute direct adenoviral vector cytotoxicity and chronic, but not acute, inflammatory responses correlate with decreased vector-mediated transgene expression in the brain Molec. Ther. 3 2001 36 46
    • (2001) Molec. Ther. , vol.3 , pp. 36-46
    • Thomas, C.E.1    Birkett, D.2    Anozie, I.3    Castro, M.G.4    Lowenstein, P.R.5
  • 33
    • 0033579358 scopus 로고    scopus 로고
    • Gene therapy death prompts review of adenovirus vector
    • E. Marshall Gene therapy death prompts review of adenovirus vector Science 286 1999 2244 2245
    • (1999) Science , vol.286 , pp. 2244-2245
    • Marshall, E.1
  • 34
    • 0036147402 scopus 로고    scopus 로고
    • Assessment of adenoviral vector safety and toxicity: Report of the National Institute of Health Recombinant DNA Advisory Committee
    • Assessment of adenoviral vector safety and toxicity: report of the National Institute of Health Recombinant DNA Advisory Committee Hum. Gene Ther. 13 2002 3 13
    • (2002) Hum. Gene Ther. , vol.13 , pp. 3-13
  • 35
    • 0020017266 scopus 로고
    • Interaction of viruses with sinusoidal cells
    • A. Kirn, J.P. Gut, and J.L. Gendrault Interaction of viruses with sinusoidal cells Prog. Liver Dis. 7 1982 377 392
    • (1982) Prog. Liver Dis. , vol.7 , pp. 377-392
    • Kirn, A.1    Gut, J.P.2    Gendrault, J.L.3
  • 36
    • 0017699907 scopus 로고
    • Comparisons among members of the Venezuelan encephalitis virus complex using hydroxylapatite column chromatography
    • P.B. Jahrling, and G.A. Eddy Comparisons among members of the Venezuelan encephalitis virus complex using hydroxylapatite column chromatography Am. J. Epidemiol. 106 1977 408 417
    • (1977) Am. J. Epidemiol. , vol.106 , pp. 408-417
    • Jahrling, P.B.1    Eddy, G.A.2
  • 37
    • 0030623809 scopus 로고    scopus 로고
    • Human adenovirus vectors for gene transfer into mammalian cells
    • M.M. Hitt, C.L. Addison, and F.L. Graham Human adenovirus vectors for gene transfer into mammalian cells Adv. Pharmacol. 40 1997 137 206
    • (1997) Adv. Pharmacol. , vol.40 , pp. 137-206
    • Hitt, M.M.1    Addison, C.L.2    Graham, F.L.3
  • 38
    • 0033756313 scopus 로고    scopus 로고
    • Blood clearance rates of adenovirus type 5 in mice
    • R. Alemany, K. Suzuki, and D.T. Curiel Blood clearance rates of adenovirus type 5 in mice J. Gen. Virol. 81 2000 2605 2609
    • (2000) J. Gen. Virol. , vol.81 , pp. 2605-2609
    • Alemany, R.1    Suzuki, K.2    Curiel, D.T.3
  • 39
    • 0031060294 scopus 로고    scopus 로고
    • Enhancement of in vivo adenovirus-mediated gene transfer and expression by prior depletion of tissue macrophages in the target organ
    • G. Wolff, S. Worgall, N. van-Rooijen, W.R. Song, B.G. Harvey, and R.G. Crystal Enhancement of in vivo adenovirus-mediated gene transfer and expression by prior depletion of tissue macrophages in the target organ J. Virol. 71 1997 624 629
    • (1997) J. Virol. , vol.71 , pp. 624-629
    • Wolff, G.1    Worgall, S.2    Van-Rooijen, N.3    Song, W.R.4    Harvey, B.G.5    Crystal, R.G.6
  • 40
    • 0031034030 scopus 로고    scopus 로고
    • Innate immune mechanisms dominate elimination of adenoviral vectors following in vivo administration
    • S. Worgall, G. Wolff, E. Falck-Pedersen, and R.G. Crystal Innate immune mechanisms dominate elimination of adenoviral vectors following in vivo administration Hum. Gene. Ther. 8 1997 37 44
    • (1997) Hum. Gene. Ther. , vol.8 , pp. 37-44
    • Worgall, S.1    Wolff, G.2    Falck-Pedersen, E.3    Crystal, R.G.4
  • 41
    • 0346872988 scopus 로고    scopus 로고
    • Characterization of in vitro and in vivo gene transfer properties of adenovirus serotype 35 vector
    • F. Sakurai, H. Mizuguchi, T. Yamaguchi, and T. Hayakawa Characterization of in vitro and in vivo gene transfer properties of adenovirus serotype 35 vector Molec. Ther. 8 2003 813 821
    • (2003) Molec. Ther. , vol.8 , pp. 813-821
    • Sakurai, F.1    Mizuguchi, H.2    Yamaguchi, T.3    Hayakawa, T.4
  • 42
    • 0344304662 scopus 로고    scopus 로고
    • Reduction of natural adenovirus tropism to mouse liver by fiber-shaft exchange in combination with both CAR- and αv integrin-binding ablation
    • N. Koizumi, H. Mizuguchi, F. Sakurai, T. Yamaguchi, Y. Watanabe, and T. Hayakawa Reduction of natural adenovirus tropism to mouse liver by fiber-shaft exchange in combination with both CAR- and αv integrin-binding ablation J. Virol. 77 2003 13062 13072
    • (2003) J. Virol. , vol.77 , pp. 13062-13072
    • Koizumi, N.1    Mizuguchi, H.2    Sakurai, F.3    Yamaguchi, T.4    Watanabe, Y.5    Hayakawa, T.6
  • 43
    • 0035158631 scopus 로고    scopus 로고
    • Reducing the native tropism of adenovirus vectors requires removal of both CAR and integrin interactions
    • D.A. Einfeld, R. Schroeder, P.W. Roelvink, A. Lizonova, C.R. King, I. Kovesdi, and T.J. Wickham Reducing the native tropism of adenovirus vectors requires removal of both CAR and integrin interactions J. Virol. 75 2001 11284 11291
    • (2001) J. Virol. , vol.75 , pp. 11284-11291
    • Einfeld, D.A.1    Schroeder, R.2    Roelvink, P.W.3    Lizonova, A.4    King, C.R.5    Kovesdi, I.6    Wickham, T.J.7
  • 45
    • 0034980914 scopus 로고    scopus 로고
    • Sequestration of adenoviral vector by Kupffer cells leads to a nonlinear dose response of transduction in liver
    • N. Tao, G.P. Gao, M. Parr, J. Johnston, T. Baradet, J.M. Wilson, J. Barsoum, and S.E. Fawell Sequestration of adenoviral vector by Kupffer cells leads to a nonlinear dose response of transduction in liver Molec. Ther. 3 2001 28 35
    • (2001) Molec. Ther. , vol.3 , pp. 28-35
    • Tao, N.1    Gao, G.P.2    Parr, M.3    Johnston, J.4    Baradet, T.5    Wilson, J.M.6    Barsoum, J.7    Fawell, S.E.8
  • 47
    • 0028914687 scopus 로고
    • Strain related variations in adenoviral-mediated transgene expression from mouse hepatocytes in vivo: Comparisions between immunocompetent and immunodeficient inbred strains
    • D. Barr, J. Tubb, D. Ferguson, A. Scaria, A. Lieber, C. Wilson, J. Perkins, and M.A. Kay Strain related variations in adenoviral-mediated transgene expression from mouse hepatocytes in vivo: comparisions between immunocompetent and immunodeficient inbred strains Gene Ther. 2 1995 151 154
    • (1995) Gene Ther. , vol.2 , pp. 151-154
    • Barr, D.1    Tubb, J.2    Ferguson, D.3    Scaria, A.4    Lieber, A.5    Wilson, C.6    Perkins, J.7    Kay, M.A.8
  • 48
    • 0033065425 scopus 로고    scopus 로고
    • Implication of interfering antibody formation and apoptosis as two different mechanisms leading to variable duration of adenovirus-mediated transgene expression in immune-competent mice
    • D.B. Schowalter, C.L. Himeda, B.L. Winther, C.B. Wilson, and M.A. Kay Implication of interfering antibody formation and apoptosis as two different mechanisms leading to variable duration of adenovirus-mediated transgene expression in immune-competent mice J. Virol. 73 1999 4755 4766
    • (1999) J. Virol. , vol.73 , pp. 4755-4766
    • Schowalter, D.B.1    Himeda, C.L.2    Winther, B.L.3    Wilson, C.B.4    Kay, M.A.5
  • 51
    • 0034986027 scopus 로고    scopus 로고
    • Generation and characterization of E1/E2a/E3/E4-deficient adenoviral vectors encoding human factor VIII
    • J.L. Andrews, M.J. Kadan, M.I. Gorziglia, M. Kaleko, and S. Connelly Generation and characterization of E1/E2a/E3/E4-deficient adenoviral vectors encoding human factor VIII Molec. Ther. 3 3 2001 329 336
    • (2001) Molec. Ther. , vol.3 , Issue.3 , pp. 329-336
    • Andrews, J.L.1    Kadan, M.J.2    Gorziglia, M.I.3    Kaleko, M.4    Connelly, S.5
  • 53
    • 0035818555 scopus 로고    scopus 로고
    • Lifetime correction of genetic deficiency in mice with a single injection of helper-dependent adenoviral vector
    • I.H. Kim, A. Józkowicz, P.A. Piedra, K. Oka, and L. Chan Lifetime correction of genetic deficiency in mice with a single injection of helper-dependent adenoviral vector Proc. Natl. Acad. Sci. U. S. A. 98 2001 13282 13287
    • (2001) Proc. Natl. Acad. Sci. U. S. A. , vol.98 , pp. 13282-13287
    • Kim, I.H.1    Józkowicz, A.2    Piedra, P.A.3    Oka, K.4    Chan, L.5
  • 56
    • 0141593513 scopus 로고    scopus 로고
    • A gene-deleted adenoviral vector results in phenotypic correction of canine hemophilia B without liver toxicity or thrombocytopenia
    • A. Ehrhardt, H. Xu, A.M. Dillow, D.A. Bellinger, T.C. Nichols, and M.A. Kay A gene-deleted adenoviral vector results in phenotypic correction of canine hemophilia B without liver toxicity or thrombocytopenia Blood 102 2003 2403 2411
    • (2003) Blood , vol.102 , pp. 2403-2411
    • Ehrhardt, A.1    Xu, H.2    Dillow, A.M.3    Bellinger, D.A.4    Nichols, T.C.5    Kay, M.A.6
  • 57
    • 0036592086 scopus 로고    scopus 로고
    • A new adenoviral helper-dependent vector results in long-term therapeutic levels of human coagulation factor IX at low doses in vivo
    • A. Ehrhardt, and M.A. Kay A new adenoviral helper-dependent vector results in long-term therapeutic levels of human coagulation factor IX at low doses in vivo Blood 99 2002 3923 3930
    • (2002) Blood , vol.99 , pp. 3923-3930
    • Ehrhardt, A.1    Kay, M.A.2
  • 59
    • 0030462599 scopus 로고    scopus 로고
    • A helper-dependent adenovirus vector system: Removal of helper virus by Cre-mediated excision of the viral packaging signal
    • R.J. Parks, L. Chen, M. Anton, U. Sankar, M.A. Rudnicki, and F.L. Graham A helper-dependent adenovirus vector system: removal of helper virus by Cre-mediated excision of the viral packaging signal Proc. Natl. Acad. Sci. U. S. A. 93 1996 13565 13570
    • (1996) Proc. Natl. Acad. Sci. U. S. A. , vol.93 , pp. 13565-13570
    • Parks, R.J.1    Chen, L.2    Anton, M.3    Sankar, U.4    Rudnicki, M.A.5    Graham, F.L.6
  • 60
    • 0030054785 scopus 로고    scopus 로고
    • Adenovirus-mediated gene transfer of herpes simplex virus thymidine kinase in an ascites model of human breast cancer
    • D. Yee, S.E. McGuire, N. Brunner, T.W. Kozelsky, D.C. Allred, S.H. Chen, and S.L. Woo Adenovirus-mediated gene transfer of herpes simplex virus thymidine kinase in an ascites model of human breast cancer Hum. Gene Ther. 7 1996 1251 1257
    • (1996) Hum. Gene Ther. , vol.7 , pp. 1251-1257
    • Yee, D.1    McGuire, S.E.2    Brunner, N.3    Kozelsky, T.W.4    Allred, D.C.5    Chen, S.H.6    Woo, S.L.7
  • 61
    • 0035175933 scopus 로고    scopus 로고
    • Systemic vector leakage and transgene expression by intratumorally injected recombinant adenovirus vectors
    • F. Lohr, Q. Huang, K. Hu, M.W. Dewhirst, and C.Y. Li Systemic vector leakage and transgene expression by intratumorally injected recombinant adenovirus vectors Clin. Cancer Res. 7 2001 3625 3628
    • (2001) Clin. Cancer Res. , vol.7 , pp. 3625-3628
    • Lohr, F.1    Huang, Q.2    Hu, K.3    Dewhirst, M.W.4    Li, C.Y.5
  • 62
    • 0036200923 scopus 로고    scopus 로고
    • Enhanced antitumor effect and reduced vector dissemination with fiber-modified adenovirus vectors expressing herpes simplex virus thymidine kinase
    • H. Mizuguchi, and T. Hayakawa Enhanced antitumor effect and reduced vector dissemination with fiber-modified adenovirus vectors expressing herpes simplex virus thymidine kinase Cancer Gene Ther. 9 2002 236 242
    • (2002) Cancer Gene Ther. , vol.9 , pp. 236-242
    • Mizuguchi, H.1    Hayakawa, T.2
  • 63
    • 17344365922 scopus 로고    scopus 로고
    • Adenovirus-mediated herpes simplex virus thymidine kinase/ganciclovir gene therapy in patients with localized malignancy: Results of a phase I clinical trial in malignant mesothelioma
    • D.H. Sterman, J. Treat, L.A. Litzky, K.M. Amin, L. Coonrod, K. Molnar-Kimber, A. Recio, L. Knox, J.M. Wilson, S.M. Albelda, and L.R. Kaiser Adenovirus-mediated herpes simplex virus thymidine kinase/ganciclovir gene therapy in patients with localized malignancy: results of a phase I clinical trial in malignant mesothelioma Hum. Gene Ther. 9 1998 1083 1092
    • (1998) Hum. Gene Ther. , vol.9 , pp. 1083-1092
    • Sterman, D.H.1    Treat, J.2    Litzky, L.A.3    Amin, K.M.4    Coonrod, L.5    Molnar-Kimber, K.6    Recio, A.7    Knox, L.8    Wilson, J.M.9    Albelda, S.M.10    Kaiser, L.R.11
  • 64
    • 17444427673 scopus 로고    scopus 로고
    • Differential susceptibility of primary and established human glioma cells to adenovirus infection: Targeting via the epidermal growth factor receptor achieves fiber receptor-independent gene transfer
    • C.R. Miller, D.J. Buchsbaum, P.N. Reynolds, J.T. Douglas, G.Y. Gillespie, M.S. Mayo, D. Raben, and D.T. Curiel Differential susceptibility of primary and established human glioma cells to adenovirus infection: targeting via the epidermal growth factor receptor achieves fiber receptor-independent gene transfer Cancer Res. 58 1998 5738 5748
    • (1998) Cancer Res. , vol.58 , pp. 5738-5748
    • Miller, C.R.1    Buchsbaum, D.J.2    Reynolds, P.N.3    Douglas, J.T.4    Gillespie, G.Y.5    Mayo, M.S.6    Raben, D.7    Curiel, D.T.8
  • 65
    • 0033556093 scopus 로고    scopus 로고
    • Loss of adenoviral receptor expression in human bladder cancer cells: A potential impact on the efficacy of gene therapy
    • Y. Li, R.C. Pong, J.M. Bergelson, M.C. Hall, A.I. Sagalowsky, C.P. Tseng, Z. Wang, and J.T. Hsieh Loss of adenoviral receptor expression in human bladder cancer cells: a potential impact on the efficacy of gene therapy Cancer Res. 59 1999 325 330
    • (1999) Cancer Res. , vol.59 , pp. 325-330
    • Li, Y.1    Pong, R.C.2    Bergelson, J.M.3    Hall, M.C.4    Sagalowsky, A.I.5    Tseng, C.P.6    Wang, Z.7    Hsieh, J.T.8
  • 66
    • 0034665382 scopus 로고    scopus 로고
    • The dual impact of coxsackie and adenovirus receptor expression on human prostate cancer gene therapy
    • T. Okegawa, Y. Li, R.C. Pong, J.M. Bergelson, J. Zhou, and J.T. Hsieh The dual impact of coxsackie and adenovirus receptor expression on human prostate cancer gene therapy Cancer Res. 60 2000 5031 5036
    • (2000) Cancer Res. , vol.60 , pp. 5031-5036
    • Okegawa, T.1    Li, Y.2    Pong, R.C.3    Bergelson, J.M.4    Zhou, J.5    Hsieh, J.T.6
  • 67
    • 0033541587 scopus 로고    scopus 로고
    • Expression of the primary coxsackie and adenovirus receptor is downregulated during skeletal muscle maturation and limits the efficacy of adenovirus-mediated gene delivery to muscle cells
    • J. Nalbantoglu, G. Pari, G. Karpati, and P.C. Holland Expression of the primary coxsackie and adenovirus receptor is downregulated during skeletal muscle maturation and limits the efficacy of adenovirus-mediated gene delivery to muscle cells Hum. Gene Ther. 10 1999 1009 1019
    • (1999) Hum. Gene Ther. , vol.10 , pp. 1009-1019
    • Nalbantoglu, J.1    Pari, G.2    Karpati, G.3    Holland, P.C.4
  • 68
    • 0029858682 scopus 로고    scopus 로고
    • Adenovirus targeted to heparan-containing receptors increases its gene delivery efficiency to multiple cell types
    • T.J. Wickham, P.W. Roelvink, D.E. Brough, and I. Kovesdi Adenovirus targeted to heparan-containing receptors increases its gene delivery efficiency to multiple cell types Nat. Biotechnol. 14 1996 1570 1573
    • (1996) Nat. Biotechnol. , vol.14 , pp. 1570-1573
    • Wickham, T.J.1    Roelvink, P.W.2    Brough, D.E.3    Kovesdi, I.4
  • 71
    • 0030983936 scopus 로고    scopus 로고
    • Lack of high affinity fiber receptor activity explains the resistance of ciliated airway epithelia to adenovirus infection
    • J. Zabner, P. Freimuth, A. Puga, A. Fabrega, and M.J. Welsh Lack of high affinity fiber receptor activity explains the resistance of ciliated airway epithelia to adenovirus infection J. Clin. Invest. 100 1997 1144 1149
    • (1997) J. Clin. Invest. , vol.100 , pp. 1144-1149
    • Zabner, J.1    Freimuth, P.2    Puga, A.3    Fabrega, A.4    Welsh, M.J.5
  • 72
    • 0031777961 scopus 로고    scopus 로고
    • Limited entry of adenovirus vectors into well-differentiated airway epithelium is responsible for inefficient gene transfer
    • R.J. Pickles, D. McCarty, H. Matsui, P.J. Hart, S.H. Randell, and R.C. Boucher Limited entry of adenovirus vectors into well-differentiated airway epithelium is responsible for inefficient gene transfer J. Virol. 72 1998 6014 6023
    • (1998) J. Virol. , vol.72 , pp. 6014-6023
    • Pickles, R.J.1    McCarty, D.2    Matsui, H.3    Hart, P.J.4    Randell, S.H.5    Boucher, R.C.6
  • 74
    • 0028987384 scopus 로고
    • Upregulation of integrins alpha v beta 3 and alpha v beta 5 on human monocytes and T lymphocytes facilitates adenovirus-mediated gene delivery
    • S. Huang, R.I. Endo, and G.R. Nemerow Upregulation of integrins alpha v beta 3 and alpha v beta 5 on human monocytes and T lymphocytes facilitates adenovirus-mediated gene delivery J. Virol. 69 1995 2257 2263
    • (1995) J. Virol. , vol.69 , pp. 2257-2263
    • Huang, S.1    Endo, R.I.2    Nemerow, G.R.3
  • 76
    • 0034006112 scopus 로고    scopus 로고
    • Efficient gene transfer into human CD34(+) cells by a retargeted adenovirus vector
    • D.M. Shayakhmetov, T. Papayannopoulou, G. Stamatoyannopoulos, and A. Lieber Efficient gene transfer into human CD34(+) cells by a retargeted adenovirus vector J. Virol. 74 2000 2567 2583
    • (2000) J. Virol. , vol.74 , pp. 2567-2583
    • Shayakhmetov, D.M.1    Papayannopoulou, T.2    Stamatoyannopoulos, G.3    Lieber, A.4
  • 79
    • 0033954001 scopus 로고    scopus 로고
    • Targeting adenovirus
    • T.J. Wickham Targeting adenovirus Gene Ther. 7 2000 110 114
    • (2000) Gene Ther. , vol.7 , pp. 110-114
    • Wickham, T.J.1
  • 85
    • 0031755915 scopus 로고    scopus 로고
    • Basic fibroblast growth factor enhancement of adenovirus-mediated delivery of the herpes simplex virus thymidine kinase gene results in augmented therapeutic benefit in a murine model of ovarian cancer
    • C. Rancourt, B.E. Rogers, B.A. Sosnowski, M. Wang, A. Piche, G.F. Pierce, R.D. Alvarez, G.P. Siegal, J.T. Douglas, and D.T. Curiel Basic fibroblast growth factor enhancement of adenovirus-mediated delivery of the herpes simplex virus thymidine kinase gene results in augmented therapeutic benefit in a murine model of ovarian cancer Clin. Cancer Res. 4 1998 2455 2461
    • (1998) Clin. Cancer Res. , vol.4 , pp. 2455-2461
    • Rancourt, C.1    Rogers, B.E.2    Sosnowski, B.A.3    Wang, M.4    Piche, A.5    Pierce, G.F.6    Alvarez, R.D.7    Siegal, G.P.8    Douglas, J.T.9    Curiel, D.T.10
  • 87
    • 77953082198 scopus 로고    scopus 로고
    • Fibroblast growth factor 2-retargeted adenoviral vectors exhibit a modified biolocalization pattern and display reduced toxicity relative to native adenoviral vectors
    • M.A. Printz, A.M. Gonzalez, M. Cunningham, D.L. Gu, M. Ong, G.F. Pierce, and S.L. Aukerman Fibroblast growth factor 2-retargeted adenoviral vectors exhibit a modified biolocalization pattern and display reduced toxicity relative to native adenoviral vectors Hum. Gene Ther. 11 2000 191 204
    • (2000) Hum. Gene Ther. , vol.11 , pp. 191-204
    • Printz, M.A.1    Gonzalez, A.M.2    Cunningham, M.3    Gu, D.L.4    Ong, M.5    Pierce, G.F.6    Aukerman, S.L.7
  • 91
    • 0030831076 scopus 로고    scopus 로고
    • The 'adenobody' approach to viral targeting: Specific and enhanced adenoviral gene delivery
    • S.J. Watkins, V.V. Mesyanzhinov, L.P. Kurochkina, and R.E. Hawkins The 'adenobody' approach to viral targeting: specific and enhanced adenoviral gene delivery Gene Ther. 4 1997 1004 1012
    • (1997) Gene Ther. , vol.4 , pp. 1004-1012
    • Watkins, S.J.1    Mesyanzhinov, V.V.2    Kurochkina, L.P.3    Hawkins, R.E.4
  • 92
    • 0034636793 scopus 로고    scopus 로고
    • Selective targeting of gene transfer to vascular endothelial cells by use of peptides isolated by phage display
    • S.A. Nicklin, S.J. White, S.J. Watkins, R.E. Hawkins, and A.H. Baker Selective targeting of gene transfer to vascular endothelial cells by use of peptides isolated by phage display Circulation 102 2000 231 237
    • (2000) Circulation , vol.102 , pp. 231-237
    • Nicklin, S.A.1    White, S.J.2    Watkins, S.J.3    Hawkins, R.E.4    Baker, A.H.5
  • 95
    • 0034963191 scopus 로고    scopus 로고
    • Targeting of adenovirus to endothelial cells by a bispecific single-chain diabody directed against the adenovirus fiber knob domain and human endoglin (CD105)
    • D.M. Nettelbeck, D.W. Miller, V. Jerome, M. Zuzarte, S.J. Watkins, R.E. Hawkins, R. Muller, and R.E. Kontermann Targeting of adenovirus to endothelial cells by a bispecific single-chain diabody directed against the adenovirus fiber knob domain and human endoglin (CD105) Molec. Ther. 3 2001 882 891
    • (2001) Molec. Ther. , vol.3 , pp. 882-891
    • Nettelbeck, D.M.1    Miller, D.W.2    Jerome, V.3    Zuzarte, M.4    Watkins, S.J.5    Hawkins, R.E.6    Muller, R.7    Kontermann, R.E.8
  • 96
    • 0033925797 scopus 로고    scopus 로고
    • Ectodomain of coxsackievirus and adenovirus receptor genetically fused to epidermal growth factor mediates adenovirus targeting to epidermal growth factor receptor-positive cells
    • I. Dmitriev, E. Kashentseva, B.E. Rogers, V. Krasnykh, and D.T. Curiel Ectodomain of coxsackievirus and adenovirus receptor genetically fused to epidermal growth factor mediates adenovirus targeting to epidermal growth factor receptor-positive cells J. Virol. 74 2000 6875 6884
    • (2000) J. Virol. , vol.74 , pp. 6875-6884
    • Dmitriev, I.1    Kashentseva, E.2    Rogers, B.E.3    Krasnykh, V.4    Curiel, D.T.5
  • 98
    • 0034692421 scopus 로고    scopus 로고
    • Molecular adaptors for vascular-targeted adenoviral gene delivery
    • M. Trepel, M. Grifman, M.D. Weitzman, and R. Pasqualini Molecular adaptors for vascular-targeted adenoviral gene delivery Hum. Gene Ther. 11 2000 1971 1981
    • (2000) Hum. Gene Ther. , vol.11 , pp. 1971-1981
    • Trepel, M.1    Grifman, M.2    Weitzman, M.D.3    Pasqualini, R.4
  • 99
    • 0035097824 scopus 로고    scopus 로고
    • Identification of peptides that target the endothelial cell-specific LOX-1 receptor
    • S.J. White, S.A. Nicklin, T. Sawamura, and A.H. Baker Identification of peptides that target the endothelial cell-specific LOX-1 receptor Hypertension 37 2001 449 455
    • (2001) Hypertension , vol.37 , pp. 449-455
    • White, S.J.1    Nicklin, S.A.2    Sawamura, T.3    Baker, A.H.4
  • 100
    • 0028790770 scopus 로고
    • Addition of a short peptide ligand to the adenovirus fiber protein
    • S.I. Michael, J.S. Hong, D.T. Curiel, and J.A. Engler Addition of a short peptide ligand to the adenovirus fiber protein Gene Ther. 2 1995 660 668
    • (1995) Gene Ther. , vol.2 , pp. 660-668
    • Michael, S.I.1    Hong, J.S.2    Curiel, D.T.3    Engler, J.A.4
  • 101
    • 0031913203 scopus 로고    scopus 로고
    • Characterization of an adenovirus vector containing a heterologous peptide epitope in the HI loop of the fiber knob
    • V. Krasnykh, I. Dmitriev, G. Mikheeva, C.R. Miller, N. Belousova, and D.T. Curiel Characterization of an adenovirus vector containing a heterologous peptide epitope in the HI loop of the fiber knob J. Virol. 72 1998 1844 1852
    • (1998) J. Virol. , vol.72 , pp. 1844-1852
    • Krasnykh, V.1    Dmitriev, I.2    Mikheeva, G.3    Miller, C.R.4    Belousova, N.5    Curiel, D.T.6
  • 109
    • 0035504969 scopus 로고    scopus 로고
    • Efficient antigen gene transduction using Arg-Gly-Asp fiber-mutant adenovirus vectors can potentiate antitumor vaccine efficacy and maturation of murine dendritic cells
    • N. Okada, T. Saito, Y. Masunaga, Y. Tsukada, S. Nakagawa, H. Mizuguchi, K. Mori, Y. Okada, T. Fujita, T. Hayakawa, T. Mayumi, and A. Yamamoto Efficient antigen gene transduction using Arg-Gly-Asp fiber-mutant adenovirus vectors can potentiate antitumor vaccine efficacy and maturation of murine dendritic cells Cancer Res. 61 2001 7913 7919
    • (2001) Cancer Res. , vol.61 , pp. 7913-7919
    • Okada, N.1    Saito, T.2    Masunaga, Y.3    Tsukada, Y.4    Nakagawa, S.5    Mizuguchi, H.6    Mori, K.7    Okada, Y.8    Fujita, T.9    Hayakawa, T.10    Mayumi, T.11    Yamamoto, A.12
  • 110
    • 0035661202 scopus 로고    scopus 로고
    • Ablating adenovirus type 5 fiber-CAR binding and HI loop insertion of the SIGYPLP peptide generate an endothelial cell-selective adenovirus
    • S.A. Nicklin, D.J. Von Seggern, L.M. Work, D.C. Pek, A.F. Dominiczak, G.R. Nemerow, and A.H. Baker Ablating adenovirus type 5 fiber-CAR binding and HI loop insertion of the SIGYPLP peptide generate an endothelial cell-selective adenovirus Molec. Ther. 4 2001 534 542
    • (2001) Molec. Ther. , vol.4 , pp. 534-542
    • Nicklin, S.A.1    Von Seggern, D.J.2    Work, L.M.3    Pek, D.C.4    Dominiczak, A.F.5    Nemerow, G.R.6    Baker, A.H.7
  • 112
    • 0344661722 scopus 로고    scopus 로고
    • Generation of fiber-modified adenovirus vectors containing heterologous peptides in both the HI loop and C terminus of the fiber knob
    • N. Koizumi, H. Mizuguchi, N. Utoguchi, Y. Watanabe, and T. Hayakawa Generation of fiber-modified adenovirus vectors containing heterologous peptides in both the HI loop and C terminus of the fiber knob J. Gene Med. 5 2003 267 276
    • (2003) J. Gene Med. , vol.5 , pp. 267-276
    • Koizumi, N.1    Mizuguchi, H.2    Utoguchi, N.3    Watanabe, Y.4    Hayakawa, T.5
  • 113
    • 0345708273 scopus 로고    scopus 로고
    • CD46 is a cellular receptor for group B adenoviruses
    • A. Gaggar, D.M. Shayakhmetov, and A. Lieber CD46 is a cellular receptor for group B adenoviruses Nat. Med. 9 2003 1408 1412
    • (2003) Nat. Med. , vol.9 , pp. 1408-1412
    • Gaggar, A.1    Shayakhmetov, D.M.2    Lieber, A.3
  • 115
    • 0029869840 scopus 로고    scopus 로고
    • Adenovirus type 5 and 7 capsid chimera: Fiber replacement alters receptor tropism without affecting primary immune neutralization epitopes
    • J. Gall, A. Kass-Eisler, L. Leinwand, and E. Falck-Pedersen Adenovirus type 5 and 7 capsid chimera: fiber replacement alters receptor tropism without affecting primary immune neutralization epitopes. J. Virol. 70 1996 2116 2123
    • (1996) J. Virol. , vol.70 , pp. 2116-2123
    • Gall, J.1    Kass-Eisler, A.2    Leinwand, L.3    Falck-Pedersen, E.4
  • 116
    • 0034915218 scopus 로고    scopus 로고
    • A capsid-modified adenovirus vector devoid of all viral genes: Assessment of transduction and toxicity in human hematopoietic cells
    • H. Stecher, D.M. Shayakhmetov, G. Stamatoyannopoulos, and A. Lieber A capsid-modified adenovirus vector devoid of all viral genes: assessment of transduction and toxicity in human hematopoietic cells Molec. Ther. 4 2001 36 44
    • (2001) Molec. Ther. , vol.4 , pp. 36-44
    • Stecher, H.1    Shayakhmetov, D.M.2    Stamatoyannopoulos, G.3    Lieber, A.4
  • 119
    • 0031000327 scopus 로고    scopus 로고
    • Selective targeting of human cells by a chimeric adenovirus vector containing a modified fiber protein
    • S.C. Stevenson, M. Rollence, J. Marshall-Neff, and A. McClelland Selective targeting of human cells by a chimeric adenovirus vector containing a modified fiber protein J. Virol. 71 1997 4782 4790
    • (1997) J. Virol. , vol.71 , pp. 4782-4790
    • Stevenson, S.C.1    Rollence, M.2    Marshall-Neff, J.3    McClelland, A.4
  • 120
    • 0037227549 scopus 로고    scopus 로고
    • There are two different species B adenovirus receptors: SBAR, common to species B1 and B2 adenoviruses, and sB2AR, exclusively used by species B2 adenoviruses
    • A. Segerman, N. Arnberg, A. Erikson, K. Lindman, and G. Wadell There are two different species B adenovirus receptors: sBAR, common to species B1 and B2 adenoviruses, and sB2AR, exclusively used by species B2 adenoviruses J. Virol. 77 2003 1157 1162
    • (2003) J. Virol. , vol.77 , pp. 1157-1162
    • Segerman, A.1    Arnberg, N.2    Erikson, A.3    Lindman, K.4    Wadell, G.5
  • 123
    • 0036764768 scopus 로고    scopus 로고
    • Dual targeting of adenoviral vectors at the levels of transduction and transcription enhances the specificity of gene expression in cancer cells
    • B.G. Barnett, B.W. Tillman, D.T. Curiel, and J.T. Douglas Dual targeting of adenoviral vectors at the levels of transduction and transcription enhances the specificity of gene expression in cancer cells Molec. Ther. 6 3 2002 377 385
    • (2002) Molec. Ther. , vol.6 , Issue.3 , pp. 377-385
    • Barnett, B.G.1    Tillman, B.W.2    Curiel, D.T.3    Douglas, J.T.4
  • 124
    • 0034830243 scopus 로고    scopus 로고
    • CAR-binding ablation does not change biodistribution and toxicity of adenoviral vectors
    • R. Alemany, and D.T. Curiel CAR-binding ablation does not change biodistribution and toxicity of adenoviral vectors Gene Ther. 8 2001 1347 1353
    • (2001) Gene Ther. , vol.8 , pp. 1347-1353
    • Alemany, R.1    Curiel, D.T.2
  • 126
    • 0035998392 scopus 로고    scopus 로고
    • CAR- or αv integrin-binding ablated adenovirus vectors, but not fiber-modified vectors containing RGD peptide, do not change the systemic gene transfer properties in mice
    • H. Mizuguchi, N. Koizumi, T. Hosono, A. Ishii-Watabe, E. Uchida, N. Utoguchi, Y. Watanabe, and T. Hayakawa CAR- or αv integrin-binding ablated adenovirus vectors, but not fiber-modified vectors containing RGD peptide, do not change the systemic gene transfer properties in mice Gene Ther. 9 2002 769 776
    • (2002) Gene Ther. , vol.9 , pp. 769-776
    • Mizuguchi, H.1    Koizumi, N.2    Hosono, T.3    Ishii-Watabe, A.4    Uchida, E.5    Utoguchi, N.6    Watanabe, Y.7    Hayakawa, T.8
  • 128
    • 0033755728 scopus 로고    scopus 로고
    • Dependence of adenovirus infectivity on length of the fiber shaft domain
    • D.M. Shayakhmetov, and A. Lieber Dependence of adenovirus infectivity on length of the fiber shaft domain J. Virol. 74 2000 10274 10286
    • (2000) J. Virol. , vol.74 , pp. 10274-10286
    • Shayakhmetov, D.M.1    Lieber, A.2
  • 129
    • 0037319968 scopus 로고    scopus 로고
    • Reduction of natural adenovirus tropism to the liver by both ablation of fiber-coxsackievirus and adenovirus receptor interaction and use of replaceable short fiber
    • T. Nakamura, K. Sato, and H. Hamada Reduction of natural adenovirus tropism to the liver by both ablation of fiber-coxsackievirus and adenovirus receptor interaction and use of replaceable short fiber J. Virol. 77 2003 2512 2521
    • (2003) J. Virol. , vol.77 , pp. 2512-2521
    • Nakamura, T.1    Sato, K.2    Hamada, H.3
  • 131
    • 0029558004 scopus 로고
    • Cationic liposome-mediated gene transfer
    • X. Gao, and L. Huang Cationic liposome-mediated gene transfer Gene Ther. 2 1995 710 722
    • (1995) Gene Ther. , vol.2 , pp. 710-722
    • Gao, X.1    Huang, L.2
  • 132
    • 0028850553 scopus 로고
    • Enhancement of liposome-mediated gene transfer into vascular tissue by replication deficient adenovirus
    • R. Raja-Walia, J. Webber, J. Naftilan, G.D. Chapman, and A.J. Naftilan Enhancement of liposome-mediated gene transfer into vascular tissue by replication deficient adenovirus Gene Ther. 2 1995 521 530
    • (1995) Gene Ther. , vol.2 , pp. 521-530
    • Raja-Walia, R.1    Webber, J.2    Naftilan, J.3    Chapman, G.D.4    Naftilan, A.J.5
  • 133
    • 0029888209 scopus 로고    scopus 로고
    • Adenovirus-assisted lipofection: Efficient in vitro gene transfer of luciferase and cytosine deaminase to human smooth muscle cells
    • J. Kreuzer, S. Denger, F. Reifers, C. Beisel, K. Haack, J. Gebert, and W. Kubler Adenovirus-assisted lipofection: efficient in vitro gene transfer of luciferase and cytosine deaminase to human smooth muscle cells Atherosclerosis 124 1996 49 60
    • (1996) Atherosclerosis , vol.124 , pp. 49-60
    • Kreuzer, J.1    Denger, S.2    Reifers, F.3    Beisel, C.4    Haack, K.5    Gebert, J.6    Kubler, W.7
  • 134
    • 0030937585 scopus 로고    scopus 로고
    • Complexes of adenovirus with polycationic polymers and cationic lipids increase the efficiency of gene transfer in vitro and in vivo
    • A. Fasbender, J. Zabner, M. Chillon, T.O. Moninger, A.P. Puga, B.L. Davidson, and M.J. Welsh Complexes of adenovirus with polycationic polymers and cationic lipids increase the efficiency of gene transfer in vitro and in vivo J. Biol. Chem. 272 1997 6479 6489
    • (1997) J. Biol. Chem. , vol.272 , pp. 6479-6489
    • Fasbender, A.1    Zabner, J.2    Chillon, M.3    Moninger, T.O.4    Puga, A.P.5    Davidson, B.L.6    Welsh, M.J.7
  • 135
    • 0034098369 scopus 로고    scopus 로고
    • Transduction efficiency of adenoviral vectors into human glioma cells increased by association with cationic liposomes
    • Y. Ryuke, M. Mizuno, A. Natsume, and J. Yoshida Transduction efficiency of adenoviral vectors into human glioma cells increased by association with cationic liposomes Neurol. Med.-Chir (Tokyo) 40 2000 256 260
    • (2000) Neurol. Med.-Chir (Tokyo) , vol.40 , pp. 256-260
    • Ryuke, Y.1    Mizuno, M.2    Natsume, A.3    Yoshida, J.4
  • 136
    • 0034068970 scopus 로고    scopus 로고
    • Cationic liposome conjugation to recombinant adenoviral vector reduces viral antigenicity
    • A. Natsume, M. Mizuno, Y. Ryuke, and J. Yoshida Cationic liposome conjugation to recombinant adenoviral vector reduces viral antigenicity Jpn. J. Cancer Res. 91 2000 363 367
    • (2000) Jpn. J. Cancer Res. , vol.91 , pp. 363-367
    • Natsume, A.1    Mizuno, M.2    Ryuke, Y.3    Yoshida, J.4
  • 137
    • 0036787809 scopus 로고    scopus 로고
    • Cationic liposomes conjugation to recombinant adenoviral vectors containing herpes simplex virus thymidine kinase gene followed by ganciclovir treatment reduces viral antigenicity and maintains antitumor activity in mouse experimental glioma models
    • M. Mizuno, Y. Ryuke, and J. Yoshida Cationic liposomes conjugation to recombinant adenoviral vectors containing herpes simplex virus thymidine kinase gene followed by ganciclovir treatment reduces viral antigenicity and maintains antitumor activity in mouse experimental glioma models Cancer Gene Ther. 9 2002 825 829
    • (2002) Cancer Gene Ther. , vol.9 , pp. 825-829
    • Mizuno, M.1    Ryuke, Y.2    Yoshida, J.3
  • 139
    • 0032126845 scopus 로고    scopus 로고
    • PEGylation of cytokines and other therapeutic proteins and peptides: The importance of biological optimisation of coupling techniques
    • G.E. Francis, D. Fisher, C. Delgado, F. Malik, A. Gardiner, and D. Neale PEGylation of cytokines and other therapeutic proteins and peptides: the importance of biological optimisation of coupling techniques Int. J. Hematol. 68 1998 1 18
    • (1998) Int. J. Hematol. , vol.68 , pp. 1-18
    • Francis, G.E.1    Fisher, D.2    Delgado, C.3    Malik, F.4    Gardiner, A.5    Neale, D.6
  • 141
    • 0033587174 scopus 로고    scopus 로고
    • PEGylation of adenovirus with retention of infectivity and protection from neutralizing antibody in vitro and in vivo
    • C.R. O'Riordan, A. Lachapelle, C. Delgado, V. Parkes, S.C. Wadsworth, A.E. Smith, and G.E. Francis PEGylation of adenovirus with retention of infectivity and protection from neutralizing antibody in vitro and in vivo Hum. Gene Ther. 10 1999 1349 1358
    • (1999) Hum. Gene Ther. , vol.10 , pp. 1349-1358
    • O'Riordan, C.R.1    Lachapelle, A.2    Delgado, C.3    Parkes, V.4    Wadsworth, S.C.5    Smith, A.E.6    Francis, G.E.7
  • 142
    • 0035033758 scopus 로고    scopus 로고
    • "stealth" adenoviruses blunt cell-mediated and humoral immune responses against the virus and allow for significant gene expression upon readministration in the lung
    • M.A. Croyle, N. Chirmule, Y. Zhang, and J.M. Wilson "Stealth" adenoviruses blunt cell-mediated and humoral immune responses against the virus and allow for significant gene expression upon readministration in the lung J. Virol. 75 2001 4792 4801
    • (2001) J. Virol. , vol.75 , pp. 4792-4801
    • Croyle, M.A.1    Chirmule, N.2    Zhang, Y.3    Wilson, J.M.4
  • 143
    • 0034632396 scopus 로고    scopus 로고
    • Development of a rapid method for the PEGylation of adenoviruses with enhanced transduction and improved stability under harsh storage conditions
    • M.A. Croyle, Q.C. Yu, and J.M. Wilson Development of a rapid method for the PEGylation of adenoviruses with enhanced transduction and improved stability under harsh storage conditions Hum. Gene Ther. 11 2000 1713 1722
    • (2000) Hum. Gene Ther. , vol.11 , pp. 1713-1722
    • Croyle, M.A.1    Yu, Q.C.2    Wilson, J.M.3
  • 145
    • 0031596240 scopus 로고    scopus 로고
    • Inhibition of NF-kappaB activation in combination with bcl-2 expression allows for persistence of first-generation adenovirus vectors in the mouse liver
    • A. Lieber, C. He, L. Meuse, C. Himeda, C. Wilson, and M.A. Kay Inhibition of NF-kappaB activation in combination with bcl-2 expression allows for persistence of first-generation adenovirus vectors in the mouse liver J. Virol. 72 1998 9267 9277
    • (1998) J. Virol. , vol.72 , pp. 9267-9277
    • Lieber, A.1    He, C.2    Meuse, L.3    Himeda, C.4    Wilson, C.5    Kay, M.A.6
  • 146
    • 0141744739 scopus 로고    scopus 로고
    • Adenovirus expression of IL-1 and NF-kappaB inhibitors does not inhibit acute adenoviral-induced brain inflammation, but delays immune system-mediated elimination of transgene expression
    • D. Stone, W. Xiong, J.C. Williams, A. David, P.R. Lowenstein, and M.G. Castro Adenovirus expression of IL-1 and NF-kappaB inhibitors does not inhibit acute adenoviral-induced brain inflammation, but delays immune system-mediated elimination of transgene expression Molec. Ther. 8 2003 400 411
    • (2003) Molec. Ther. , vol.8 , pp. 400-411
    • Stone, D.1    Xiong, W.2    Williams, J.C.3    David, A.4    Lowenstein, P.R.5    Castro, M.G.6
  • 147
    • 0035447558 scopus 로고    scopus 로고
    • Budesonide enhances repeated gene transfer and expression in the lung with adenoviral vectors
    • M. Kolb, M. Inman, P.J. Margetts, T. Galt, and J. Gauldie Budesonide enhances repeated gene transfer and expression in the lung with adenoviral vectors Am. J. Respir. Crit. Care Med. 164 2001 866 872
    • (2001) Am. J. Respir. Crit. Care Med. , vol.164 , pp. 866-872
    • Kolb, M.1    Inman, M.2    Margetts, P.J.3    Galt, T.4    Gauldie, J.5
  • 148
    • 0036208586 scopus 로고    scopus 로고
    • Transplant immunosuppression enhances efficiency of adenoviral-mediated gene retransfection: Inhibition of interferon-gamma and immunoglobin G
    • M. Suga, R. Gladdy, Z. Xing, S.H. Keshavjee, and M. Liu Transplant immunosuppression enhances efficiency of adenoviral-mediated gene retransfection: inhibition of interferon-gamma and immunoglobin G Ann. Thorac. Surg. 73 2002 1092 1097
    • (2002) Ann. Thorac. Surg. , vol.73 , pp. 1092-1097
    • Suga, M.1    Gladdy, R.2    Xing, Z.3    Keshavjee, S.H.4    Liu, M.5
  • 152
    • 0029858387 scopus 로고    scopus 로고
    • TNF- and cancer therapy-induced apoptosis: Potentiation by inhibition of NF-κB
    • C.-Y. Wang, M.W. Mayo, and A.S. Baldwin TNF- and cancer therapy-induced apoptosis: potentiation by inhibition of NF-κB Science 274 1996 784 787
    • (1996) Science , vol.274 , pp. 784-787
    • Wang, C.-Y.1    Mayo, M.W.2    Baldwin, A.S.3
  • 153
    • 0030916669 scopus 로고    scopus 로고
    • The proto-oncogene Bcl-2 and its role in regulating apoptosis
    • G. Kroemer The proto-oncogene Bcl-2 and its role in regulating apoptosis Nat. Med. 3 1997 614 620
    • (1997) Nat. Med. , vol.3 , pp. 614-620
    • Kroemer, G.1
  • 154
    • 0030984335 scopus 로고    scopus 로고
    • Transient immunomodulation with anti-CD40 ligand antibody and CTLA4Ig enhances persistence and secondary adenovirus-mediated gene transfer into mouse liver
    • M.A. Kay, L. Meuse, A.M. Gown, P. Linsley, D. Hollenbaugh, A. Aruffo, H.D. Ochs, and C.B. Wilson Transient immunomodulation with anti-CD40 ligand antibody and CTLA4Ig enhances persistence and secondary adenovirus-mediated gene transfer into mouse liver Proc. Natl. Acad. Sci. U. S. A. 94 1997 4686 4691
    • (1997) Proc. Natl. Acad. Sci. U. S. A. , vol.94 , pp. 4686-4691
    • Kay, M.A.1    Meuse, L.2    Gown, A.M.3    Linsley, P.4    Hollenbaugh, D.5    Aruffo, A.6    Ochs, H.D.7    Wilson, C.B.8
  • 155
    • 0031883333 scopus 로고    scopus 로고
    • Blunting of immune responses to adenoviral vectors in mouse liver and lung with CTLA4Ig
    • K. Jooss, L.A. Turka, and J.M. Wilson Blunting of immune responses to adenoviral vectors in mouse liver and lung with CTLA4Ig Gene Ther. 5 1998 309 319
    • (1998) Gene Ther. , vol.5 , pp. 309-319
    • Jooss, K.1    Turka, L.A.2    Wilson, J.M.3
  • 156
    • 0028937785 scopus 로고
    • Cellular and humoral immune responses to viral antigens create barriers to lung-directed gene therapy with recombinant adenoviruses
    • Y. Yang, Q. Li, H.C. Ertl, and J.M. Wilson Cellular and humoral immune responses to viral antigens create barriers to lung-directed gene therapy with recombinant adenoviruses J. Virol. 69 1995 2004 2015
    • (1995) J. Virol. , vol.69 , pp. 2004-2015
    • Yang, Y.1    Li, Q.2    Ertl, H.C.3    Wilson, J.M.4
  • 157
    • 0034328925 scopus 로고    scopus 로고
    • Gene therapy: Trials and tribulations
    • N. Somia, and I.M. Verma Gene therapy: trials and tribulations Nat. Rev. Genet. 1 2000 91 99
    • (2000) Nat. Rev. Genet. , vol.1 , pp. 91-99
    • Somia, N.1    Verma, I.M.2
  • 158
    • 0038699545 scopus 로고    scopus 로고
    • Woodchuck hepatitis virus post-transcriptional regulation element enhances transgene expression from adenovirus vectors
    • Z.L. Xu, H. Mizuguchi, T. Mayumi, and T. Hayakawa Woodchuck hepatitis virus post-transcriptional regulation element enhances transgene expression from adenovirus vectors Biochim. Biophys. Acta 1621 2003 266 271
    • (2003) Biochim. Biophys. Acta , vol.1621 , pp. 266-271
    • Xu, Z.L.1    Mizuguchi, H.2    Mayumi, T.3    Hayakawa, T.4
  • 159
    • 0037123721 scopus 로고    scopus 로고
    • Strength evaluation of transcriptional regulatory elements for transgene expression by adenovirus vector
    • Z.L. Xu, H. Mizuguchi, A. Ishii-Watabe, E. Uchida, T. Mayumi, and T. Hayakawa Strength evaluation of transcriptional regulatory elements for transgene expression by adenovirus vector J. Control. Release 81 2002 155 163
    • (2002) J. Control. Release , vol.81 , pp. 155-163
    • Xu, Z.L.1    Mizuguchi, H.2    Ishii-Watabe, A.3    Uchida, E.4    Mayumi, T.5    Hayakawa, T.6
  • 160
    • 0034294843 scopus 로고    scopus 로고
    • Strong promoters are the key to highly efficient, noninflammatory and noncytotoxic adenoviral-mediated transgene delivery into the brain in vivo
    • C.A. Gerdes, M.G. Castro, and P.R. Lowenstein Strong promoters are the key to highly efficient, noninflammatory and noncytotoxic adenoviral-mediated transgene delivery into the brain in vivo Molec. Ther. 2 2000 330 338
    • (2000) Molec. Ther. , vol.2 , pp. 330-338
    • Gerdes, C.A.1    Castro, M.G.2    Lowenstein, P.R.3
  • 161
    • 0034904598 scopus 로고    scopus 로고
    • Silencing of gene expression: Implications for design of retrovirus vectors
    • D. Pannell, and J. Ellis Silencing of gene expression: implications for design of retrovirus vectors Rev. Med. Virol. 11 2001 205 217
    • (2001) Rev. Med. Virol. , vol.11 , pp. 205-217
    • Pannell, D.1    Ellis, J.2
  • 162
    • 0036559334 scopus 로고    scopus 로고
    • Adenovirus as an integrating vector
    • K. Mitani, and S. Kubo Adenovirus as an integrating vector Curr. Gene Ther. 2 2002 135 144
    • (2002) Curr. Gene Ther. , vol.2 , pp. 135-144
    • Mitani, K.1    Kubo, S.2
  • 163
    • 0032876839 scopus 로고    scopus 로고
    • Integrating adenovirus-adeno-associated virus hybrid vectors devoid of all viral genes
    • A. Lieber, D.S. Steinwaerder, C.A. Carlson, and M.A. Kay Integrating adenovirus-adeno-associated virus hybrid vectors devoid of all viral genes J. Virol. 73 1999 9314 9324
    • (1999) J. Virol. , vol.73 , pp. 9314-9324
    • Lieber, A.1    Steinwaerder, D.S.2    Carlson, C.A.3    Kay, M.A.4
  • 165
    • 0037225983 scopus 로고    scopus 로고
    • Integration efficiency of a hybrid adenoretroviral vector
    • C. Zheng, J. Wang, and B.J. Baum Integration efficiency of a hybrid adenoretroviral vector Biochem. Biophys. Res. Commun. 300 2003 115 120
    • (2003) Biochem. Biophys. Res. Commun. , vol.300 , pp. 115-120
    • Zheng, C.1    Wang, J.2    Baum, B.J.3
  • 166
    • 0036789403 scopus 로고    scopus 로고
    • Transposition from a gutless adeno-transposon vector stabilizes transgene expression in vivo
    • S.R. Yant, A. Ehrhardt, J.G. Mikkelsen, L. Meuse, T. Pham, and M.A. Kay Transposition from a gutless adeno-transposon vector stabilizes transgene expression in vivo Nat. Biotechnol. 20 2002 999 1005
    • (2002) Nat. Biotechnol. , vol.20 , pp. 999-1005
    • Yant, S.R.1    Ehrhardt, A.2    Mikkelsen, J.G.3    Meuse, L.4    Pham, T.5    Kay, M.A.6
  • 167
    • 0030662074 scopus 로고    scopus 로고
    • Molecular reconstruction of Sleeping Beauty, a Tc1-like transposon from fish, and its transposition in human cells
    • Z. Ivics, P.B. Hackett, R.H. Plasterk, and Z. Izsvak Molecular reconstruction of Sleeping Beauty, a Tc1-like transposon from fish, and its transposition in human cells Cell 91 1997 501 510
    • (1997) Cell , vol.91 , pp. 501-510
    • Ivics, Z.1    Hackett, P.B.2    Plasterk, R.H.3    Izsvak, Z.4
  • 169
    • 0037078985 scopus 로고    scopus 로고
    • A tragic setback
    • E. Check A tragic setback Nature 420 2002 116 118
    • (2002) Nature , vol.420 , pp. 116-118
    • Check, E.1
  • 170
    • 0037449534 scopus 로고    scopus 로고
    • Gene therapy. Second child in French trial is found to have leukemia
    • E. Marshall Gene therapy. Second child in French trial is found to have leukemia Science 299 2003 320
    • (2003) Science , vol.299 , pp. 320
    • Marshall, E.1
  • 172
    • 0038054338 scopus 로고    scopus 로고
    • AAV serotype 2 vectors preferentially integrate into active genes in mice
    • H. Nakai, E. Montini, S. Fuess, T.A. Storm, M. Grompe, and M.A. Kay AAV serotype 2 vectors preferentially integrate into active genes in mice Nat. Genet. 34 2003 297 302
    • (2003) Nat. Genet. , vol.34 , pp. 297-302
    • Nakai, H.1    Montini, E.2    Fuess, S.3    Storm, T.A.4    Grompe, M.5    Kay, M.A.6
  • 173
    • 0042167418 scopus 로고    scopus 로고
    • Positive and negative effects of adeno-associated virus Rep on AAVS1-targeted integration
    • M. Urabe, K. Kogure, A. Kume, Y. Sato, K. Tobita, and K. Ozawa Positive and negative effects of adeno-associated virus Rep on AAVS1-targeted integration J. Gen. Virol. 84 2003 2127 2132
    • (2003) J. Gen. Virol. , vol.84 , pp. 2127-2132
    • Urabe, M.1    Kogure, K.2    Kume, A.3    Sato, Y.4    Tobita, K.5    Ozawa, K.6
  • 174
    • 0034168963 scopus 로고    scopus 로고
    • Stable transduction of actively dividing cells via a novel adenoviral/episomal vector
    • H. Leblois, C. Roche, N. Di Falco, C. Orsini, P. Yeh, and M. Perricaudet Stable transduction of actively dividing cells via a novel adenoviral/episomal vector Molec. Ther. 1 2000 314 322
    • (2000) Molec. Ther. , vol.1 , pp. 314-322
    • Leblois, H.1    Roche, C.2    Di Falco, N.3    Orsini, C.4    Yeh, P.5    Perricaudet, M.6
  • 175
    • 0345734204 scopus 로고    scopus 로고
    • Long-term transgene expression in proliferating cells mediated by episomally maintained high-capacity adenovirus vectors
    • F. Kreppel, and S. Kochanek Long-term transgene expression in proliferating cells mediated by episomally maintained high-capacity adenovirus vectors J. Virol. 78 2004 9 22
    • (2004) J. Virol. , vol.78 , pp. 9-22
    • Kreppel, F.1    Kochanek, S.2
  • 176
    • 0031743088 scopus 로고    scopus 로고
    • Construction and characterization of hexon-chimeric adenoviruses: Specification of adenovirus serotype
    • J.G. Gall, R.G. Crystal, and E. Falck-Pedersen Construction and characterization of hexon-chimeric adenoviruses: specification of adenovirus serotype J. Virol. 72 1998 10260 10264
    • (1998) J. Virol. , vol.72 , pp. 10260-10264
    • Gall, J.G.1    Crystal, R.G.2    Falck-Pedersen, E.3
  • 177
    • 0031903186 scopus 로고    scopus 로고
    • Circumvention of immunity to the adenovirus major coat protein hexon
    • S. Roy, P.S. Shirley, A. McClelland, and M. Kaleko Circumvention of immunity to the adenovirus major coat protein hexon J. Virol. 72 1998 6875 6879
    • (1998) J. Virol. , vol.72 , pp. 6875-6879
    • Roy, S.1    Shirley, P.S.2    McClelland, A.3    Kaleko, M.4
  • 179
    • 0242351068 scopus 로고    scopus 로고
    • Human adenovirus type 35: Nucleotide sequence and vector development
    • W. Gao, P.D. Robbins, and A. Gambotto Human adenovirus type 35: nucleotide sequence and vector development Gene Ther. 10 2003 1941 1949
    • (2003) Gene Ther. , vol.10 , pp. 1941-1949
    • Gao, W.1    Robbins, P.D.2    Gambotto, A.3
  • 182
    • 0037670220 scopus 로고    scopus 로고
    • Efficient gene transfer into human CD34+ cells by an adenovirus type 35 vector
    • F. Sakurai, H. Mizuguchi, and T. Hayakawa Efficient gene transfer into human CD34+ cells by an adenovirus type 35 vector Gene Ther. 10 2003 1041 1048
    • (2003) Gene Ther. , vol.10 , pp. 1041-1048
    • Sakurai, F.1    Mizuguchi, H.2    Hayakawa, T.3
  • 183
    • 0032773548 scopus 로고    scopus 로고
    • Mouse adenovirus (MAV-1) expression in primary human endothelial cells and generation of a full-length infectious plasmid
    • T. Nguyen, J. Nery, S. Joseph, C. Rocha, G. Carney, K. Spindler, and L. Villarreal Mouse adenovirus (MAV-1) expression in primary human endothelial cells and generation of a full-length infectious plasmid Gene Ther. 6 1999 1291 1297
    • (1999) Gene Ther. , vol.6 , pp. 1291-1297
    • Nguyen, T.1    Nery, J.2    Joseph, S.3    Rocha, C.4    Carney, G.5    Spindler, K.6    Villarreal, L.7
  • 184
  • 186
    • 0033989650 scopus 로고    scopus 로고
    • Canine adenovirus vectors: An alternative for adenovirus-mediated gene transfer
    • E.J. Kremer, S. Boutin, M. Chillon, and O. Danos Canine adenovirus vectors: an alternative for adenovirus-mediated gene transfer J. Virol. 74 2000 505 512
    • (2000) J. Virol. , vol.74 , pp. 505-512
    • Kremer, E.J.1    Boutin, S.2    Chillon, M.3    Danos, O.4
  • 187
    • 0034691085 scopus 로고    scopus 로고
    • Circumvention of vector-specific neutralizing antibody response by alternating use of human and non-human adenoviruses: Implications in gene therapy
    • S. Moffatt, J. Hays, H. HogenEsch, and S.K. Mittal Circumvention of vector-specific neutralizing antibody response by alternating use of human and non-human adenoviruses: implications in gene therapy Virology 272 2000 159 167
    • (2000) Virology , vol.272 , pp. 159-167
    • Moffatt, S.1    Hays, J.2    Hogenesch, H.3    Mittal, S.K.4


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