Suppression of TNF-α-induced apoptosis by NF-κB

Science

Volumn 274, Issue 5288, 1996, Pages 787-789

  Van Antwerp, Daniel J ^a,b   Martin, Seamus J ^c,d   Kafri, Tal ^a   Green, Douglas R ^c   Verma, Inder M ^a  

^a SALK INSTITUTE FOR BIOLOGICAL STUDIES   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY   (United States)

^d ST PATRICK S COLLEGE   (Ireland)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; TUMOR NECROSIS FACTOR ALPHA;

APOPTOSIS; ARTICLE; CELL DEATH; CELL TYPE; CYTOTOXICITY; NEGATIVE FEEDBACK; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

ANIMALS; ANNEXIN A5; APOPTOSIS; CELLS, CULTURED; DNA-BINDING PROTEINS; FEEDBACK; HUMANS; I-KAPPA B PROTEINS; JURKAT CELLS; MICE; NF-KAPPA B; PHOSPHATIDYLSERINES; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0029992609     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.274.5288.787     Document Type: Article

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36. We are grateful to B. Sha, A. Beg, and D. Baltimore for p50 and RelA knockout fibroblast cell lines and to D Trono for Jurkat cells We thank members of the Verma laboratory for helpful discussions, P. Charon for help in manuscript preparation, and D. Finucane for assistance with flow cytometry. D.J.V. is a graduate student in the Department of Chemistry and Biochemistry at the University of California, San Diego, and is supported by a fellowship from the Chapman Charitable Trust, S.J.M. is a Wellcome Trust Senior Fellow. T.K. is supported by a European Molecular Biology Organization Fellowship. D.R.G.'s laboratory is supported by grants GM52735 from the National Institutes of Health and CB-82 from the American Cancer Society. I.M.V.'s laboratory is supported by grants from the NIH and American Cancer Society. I.M.V. Is an American Cancer Society Professor of Molecular Biology.