Acute cytokine response to systemic adenoviral vectors in mice is mediated by dendritic cells and macrophages

Molecular Therapy

Volumn 3, Issue 5, 2001, Pages 697-707

  Zhang, Yi ^a   Chirmule, Narendra ^a   Gao, Guang Ping ^a   Qian, Ruth ^a   Croyle, Maria ^a   Joshi, Bindu ^a   Tazelaar, John ^a   Wilson, James M ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Adenovirus; Antigen presenting cells; Gene therapy; Inflammatory cytokines; Innate immunity

Indexed keywords

BETA GALACTOSIDASE; CD86 ANTIGEN; CYTOKINE; GENE PRODUCT; IA ANTIGEN; INTERLEUKIN 12; INTERLEUKIN 6; TUMOR NECROSIS FACTOR ALPHA; VIRUS VECTOR;

ADENOVIRUS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN EXPRESSION; ARTICLE; CELL ACTIVATION; CELL CULTURE; CELL FUNCTION; CELLULAR IMMUNITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DENDRITIC CELL; ESCHERICHIA COLI; FLOW CYTOMETRY; GENE ACTIVATION; GENETIC TRANSDUCTION; IN VITRO STUDY; IN VIVO STUDY; INFLAMMATION; MACROPHAGE; MOUSE; NONHUMAN; SPLEEN; TRANSGENE;

ADENOVIRIDAE; ALPHAVIRUS; ANIMALIA; ESCHERICHIA COLI;

EID: 0034986416     PISSN: 15250016     EISSN: None     Source Type: Journal    
DOI: 10.1006/mthe.2001.0329     Document Type: Article

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