Identification of peptides that target the endothelial cell-specific LOX-1 receptor

Hypertension

Volumn 37, Issue 2 II, 2001, Pages 449-455

  White, Steve J ^a   Nicklin, Stuart A ^b   Sawamura, Tatsuya ^c   Baker, Andrew H ^b  

^a UNIVERSITY OF BRISTOL   (United Kingdom)

^b UNIVERSITY OF GLASGOW   (United Kingdom)

^c NATIONAL CEREBRAL AND CARDIOVASCULAR CENTER   (Japan)

Author keywords

Amino acids; Endothelium; Gene therapy; Hypertension; Peptides

Indexed keywords

OXIDIZED LOW DENSITY LIPOPROTEIN;

ATHEROGENESIS; ATHEROSCLEROSIS; CONFERENCE PAPER; CONSENSUS SEQUENCE; CONTROLLED STUDY; ENDOTHELIUM CELL; GENE OVEREXPRESSION; GENE TARGETING; GENE TRANSFER; HUMAN; HUMAN CELL; HYPERTENSION; LIGAND BINDING; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; VASCULAR ENDOTHELIUM;

EID: 0035097824     PISSN: 0194911X     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.hyp.37.2.449     Document Type: Conference Paper

References (33)

1. Prevention of vein graft failure: Potential applications for gene therapy
2. Gene therapy of restenosis
3. Is gene therapy for hypertension possible?
4. Adenovirus-mediated in vivo gene transfer and expression in normal rat liver
5. Comparison of adenovirus gene transfer to vascular endothelial cells in cell culture, organ culture, and in vivo
6. In vivo gene transfer and expression in normal uninjured blood vessels using replication-deficient recombinant adenovirus vectors
7. Acute host-mediated endothelial injury after adenoviral gene transfer in normal rabbit arteries
8. Selective targeting of gene transfer to vascular endothelial cells by use of peptides isolated by phage display
9. An endothelial receptor for oxidized low-density lipoprotein
10. Expression of lectin-like oxidized low-density lipoprotein receptor-1 in human atherosclerotic lesions
11. Increased expression of lectinlike oxidized LDL receptor-1 in initial atherosclerotic lesions of Watanabe heritable hyperlipidemic rabbits
12. Enhanced expression of endothelial oxidized low-density lipoprotein receptor (LOX-1) in hypertensive rats
13. Induction of the lectin-like oxidized low-density lipoprotein receptor LOX-1 by lysophosphatidylcholine in cultured endothelial cells
14. Episomal vectors rapidly and stably produce high-titer recombinant retrovirus
15. A simple technique for the rescue of early region I mutations into infectious human adenovirus type 5
16. Simple methods for preparing recombinant adenoviruses for high efficiency transduction of vascular cells
17. Constitutive and enhanced expression from the CMV major IE promoter in a defective adenovirus vector
18. Divergent effects of tissue inhibitor of metalloproteinase-1,-2 or -3 overexpression on rat vascular smooth muscle cell invasion, proliferation and death in vitro
19. Serum-induced proliferation of rabbit aortic smooth muscle cells from the contractile state is inhibited by 8-Br-cAMP but not 8-Br-cGMP
20. Cleavage of structural proteins during assembly of the head of bacteriophage T4
21. 1 increases the expression of lectin-like oxidised low-density lipoprotein receptor-1
22. Recombinant human adenovirus: Targeting to the human transferrin receptor improves gene transfer to brain microcapillary endothelium
23. v integrins
24. Cancer treatment by targeted drug delivery to tumor vasculature in a mouse model
25. Molecular heterogeneity of the vascular endothelium revealed by in vivo phage display
26. Organ targeting in vivo using phage display peptide libraries
27. Membrane dipeptidase is the receptor for a lung-targeting peptide identified by in vivo phage display
28. Molecular adaptors for vascular-targeted adenoviral gene deliver
29. Novel peptides selected to bind to vascular endothelial growth factor receptor-binding site
30. Targeting of adenovirus penton base to new receptors through replacement of its RGD motif with other receptor-specific peptide motifs
31. Integrin-mediated transfection with peptides containing arginine-glycine-aspartic acid domains
32. Targeting an adenoviral gene vector to cytokine-activated vascular endothelium via E-selectin
33. Modification of an adenoviral vector with biologically selected peptides: A novel strategy for gene delivery to cells of choice