An advanced generation of adenoviral vectors selectively enhances gene transfer for ovarian cancer gene therapy approaches

Gynecologic Oncology

Volumn 74, Issue 2, 1999, Pages 227-234

  Vanderkwaak, Timothy J ^a   Wang, Minghui ^b   Gómez Navarro, Jesús ^b   Rancourt, Claudine ^b   Dmitriev, Igor ^b   Krasnykh, Victor ^b   Barnes, Mack ^a   Siegal, Gene P ^c,d,e   Alvarez, Ronald ^a   Curiel, David T ^b  

^a UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^b UNIVERSITY OF ALABAMA SCHOOL OF MEDICINE   (United States)

^c University of Alabama at Birmingham   (United States)

^d UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^e University of Alabama at Birmingham   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARGININE; ASPARTIC ACID; GLYCINE; INTEGRIN; LUCIFERASE; VIRUS VECTOR;

ADENOVIRUS; ARTICLE; CANCER CELL CULTURE; CONTROLLED STUDY; FEMALE; GENE THERAPY; GENE TRANSFER; GENETIC ANALYSIS; HUMAN; HUMAN CELL; MESOTHELIUM; NONHUMAN; OVARY CANCER; PRIORITY JOURNAL;

EID: 0032765539     PISSN: 00908258     EISSN: None     Source Type: Journal    
DOI: 10.1006/gyno.1999.5432     Document Type: Article

References (31)

1. Landis SH, Murray T, Bolden S, Wingo PA: Cancer statistics, 1998. CA Cancer J Clin 48:6-29, 1998
2. Ozols RF, Schwartz PE, Eifel PJ: Ovarian cancer, fallopian tube carcinoma and peritoneal carcinoma; in DeVita VT, Hellman S, Rosenberg SA (eds): Cancer: Principles and Practice of Oncology. Philadelphia, Lippincott-Raven, 1998, pp 1502-1540
3. Weinberg RA: How cancer arises. Sci Am 275:62-70, 1996
4. Blaese RM: Gene therapy for cancer. Sci Am 276:111-115, 1997
5. Gomez-Navarro J, Siegal GP, Alvarez RD, Curiel DT: Gene therapy: ovarian carcinoma as the paradigm. Am J Clin Pathol 109:444-467, 1998
6. Anderson WF: Human gene therapy. Nature 392:25-30, 1998
7. Orkin SH, Motulsky AG: Report and Recommendations of the Panel to Assess the NIH Investment in Research on Gene Therapy. http://www. nih.gov/od/orda/panelrep.htm
8. Krasnykh V, Dmitriev I, Mikheeva G, Miller CR, Belousova N, Curiel DT: Characterization of an adenovirus vector containing a heterologous peptide epitope in the HI loop of the fiber knob. J Virol 72:1844-1852, 1998
9. Dmitriev I, Krasnykh V, Miller CR, Wang M, Kashentseva E, Mikheeva G, Belousova N, Curiel DT: An adenovirus vector with genetically modified fibers demonstrates expanded tropism via utilization of a coxsackievirus and adenovirus receptor-independent cell entry mechanism. J Virol 72:9706-9713, 1998
10. Bergelson JM, Cunningham JA, Droguett G, Kurt-Jones EA, Krithivas A, Hong JS, Horwitz MS, Crowell RL, Finberg RW: Isolation of a common receptor for Coxsackie B viruses and adenoviruses 2 and 5. Science 275:1320-1323, 1997
11. Tomko RP, Xu R, Philipson L: HCAR and MCAR: the human and mouse cellular receptors for subgroup C adenoviruses and group B coxsackieviruses. Proc Natl Acad Sci USA 94:3352-3356, 1997
12. Krasnykh VN, Mikheeva GV, Douglas JT, Curiel DT: Generation of recombinant adenovirus vectors with modified fibers for altering viral tropism. J Virol 70:6839-6846, 1996
13. Sterman DH, Treat J, Litzky LA, Amin KM, Coonrod L, Molnar-Kimber K, Recio A, Knox L, Wilson JM, Albelda SM, Kaiser LR: Adenovirus-mediated herpes simplex virus thymidine kinase/ganciclovir gene therapy in patients with localized malignancy: results of a phase I clinical trial in malignant mesothelioma. Hum Gene Ther 9:1083-1092, 1998
14. Keely P, Parise L, Juliano R: Integrins and GTPases in tumour cell growth, motility and invasion. Trends Cell Biol 8:101-106, 1998
15. Sanders RJ, Mainiero F, Giancotti FG: The role of integrins in tumorigenesis and metastasis. Cancer Invest 16:329-344, 1998
16. Liapis H, Adler LM, Wick MR, Rader JS: Expression of alpha(v)beta3 integrin is less frequent in ovarian epithelial tumors of low malignant potential in contrast to ovarian carcinomas. Hum Pathol 28:443-449, 1997
17. Natali PG, Hamby CV, Felding-Habermann B, Liang B, Nicotra MR, Di Filippo F, Giannarelli D, Temponi M, Ferrone S: Clinical significance of alpha(v)beta3 integrin and intercellular adhesion molecule-1 expression in cutaneous malignant melanoma lesions. Cancer Res 57:1554-1560, 1997
18. Liapis H, Flath A, Kitazawa S: Integrin alpha V beta 3 expression by bone-residing breast cancer metastases. Diagn Mol Pahtol 5:127-135, 1996
19. Pignatelli M, Cardillo MR, Hanby A, Stamp GW: Integrins and their accessory adhesion molecules in mammary carcinomas: loss of polarization in poorly differentiated tumors. Hum Pathol 23:1159-1166, 1992
20. Tait DL, Obermiller PS, Jensen RA, Holt JT: Ovarian cancer gene therapy. Hematol Oncol Clin North Am 12:539-552, 1998
21. Bilbao G, Contreras JL, Gomez-Navarro J, Curiel DT: Improving adenoviral vectors for cancer gene therapy. Tumor Targeting 3:59-79, 1998
22. Hitt MM, Addison CL, Graham FL: Human adenovirus vectors for gene transfer into mammalian cells. Adv Pharmacol 40:137-206, 1997
23. Deshane J, Siegal GP, Wang M, Wright M, Bucy RP, Alvarez RD, Curiel DT: Transductional efficacy and safety of an intraperitoneally delivered adenovirus encoding an anti-erbB-2 intracellular single-chain antibody for ovarian cancer gene therapy. Gynecol Oncol 64:378-385, 1997
24. Alvarez RD, Curiel DT: A phase I study of recombinant adenovirus vector-mediated delivery of an anti-erbB-2 single-chain (sFv) antibody gene for previously treated ovarian and extraovarian cancer patients. Hum Gene Ther 8:229-242, 1997
25. Alvarez RD, Curiel DT: A phase I study of recombinant adenovirus vector-mediated intraperitoneal delivery of herpes simplex virus thymidine kinase (HSV-TK) gene and intravenous ganciclovir for previously treated ovarian and extraovarian cancer patients. Hum Gene Ther 8:597-613, 1997
26. Office of Recombinant DNA Activities: List of Human Protocols, http:/ www.nih.gov/od/orda/protocol.htm
27. Louis N, Fender P, Barge A, Kitts P, Chronboczek J: Cell-binding domain of adenovirus serotype 2 fiber. J Virol 68:4104-4106, 1994
28. Bergelson JM, Krithivas A, Celi L, Droguett G, Horwitz MS, Wickham T, Crowell RL, Finberg RW: The murine CAR homolog is a receptor for coxsackie B viruses and adenoviruses. J Virol 72:415-419, 1998
29. Bai M, Harfe B, Freimuth P: Mutations that alter an Arg-Gly-Asp (RGD) sequence in the adenovirus type 2 penton base protein abolish its cell-rounding activity and delay virus reproduction in flat cells. J Virol 67: 5198-5205, 1993
30. Wickham TJ, Mathias P, Cheresh DA, Nemerow GR: Integrins alpha v beta 3 and alpha v beta 5 promote adenovirus internalization but not virus attachment. Cell 73:309-319, 1993
31. Michael SI, Hong JS, Curiel DT, Engler JA: Addition of a short peptide ligand to the adenovirus fiber protein. Gene Ther 2:660-668, 1995